LOCUS       NZ_CP084541            21908 bp    DNA     linear   CON 20-NOV-2024
DEFINITION  Streptomyces marincola strain SCSIO 64649 chromosome, complete
            genome.
ACCESSION   NZ_CP084541
VERSION     NZ_CP084541.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces marincola
  ORGANISM  Streptomyces marincola
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Kitasatosporales; Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 6629020)
  AUTHORS   Shi,S.
  TITLE     Strepomyces indimicinicus sp. nov., an antibiotic producing
            actinomycetes isolated from the marine environment
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 6629020)
  AUTHORS   Shi,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (30-SEP-2021) Key Laboratory of Tropical Marine
            Bio-resources and Ecology, South China Sea Institute of Oceanology,
            Chinese Academy of Sciences, 164 Xingang West Road, guangzhou,
            Guangdong 510301, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. V6.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 444.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_020410765.1-RS_2024_11_18
            Annotation Date                   :: 11/18/2024 03:45:19
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,763
            CDSs (total)                      :: 5,689
            Genes (coding)                    :: 5,612
            CDSs (with protein)               :: 5,612
            Genes (RNA)                       :: 74
            rRNAs                             :: 5, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 5, 5, 5 (5S, 16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 21 of 77
            Pseudo Genes (incomplete)         :: 60 of 77
            Pseudo Genes (internal stop)      :: 2 of 77
            Pseudo Genes (multiple problems)  :: 6 of 77
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 16:57:23
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 124875
            Orig. end                         :: 146783
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP084541.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21908
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="2"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21908
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21908
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11908](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11908)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            complement(462..1895)
                     /locus_tag="LC193_RS00520"
                     /old_locus_tag="LC193_00520"
     CDS             complement(462..1895)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1169: sugar
                     transport protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012312.5"
                     /locus_tag="LC193_RS00520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LC193_00520"
                     /product="MFS transporter"
                     /protein_id="WP_226070170.1"
                     /transl_table=11
                     /translation="MSTSQPAVIRRPQDVVDLVNSHPAKRGGTGVALIALGGVLIDAYQ
                     AAMVGFGNSYIADEYDISTGAAAAVNATVLVAALVGGLMARPLIERLGQRRAFLLGMGL
                     CTVAAAAVAFAPSIWFVLLCRVVMGIGLGIDFPLATSAVVELSGSKSSKSGRSVNLWQM
                     GWYISTTVVYLVLLPLHQATSVESDLWRYGIFVGAAFAALVMVLRYVFIGESALWAARR
                     QRYDEAVRILRERYGVHAVVAHDAVGAAPGSERPRVRGAYRVMFNRTYRRRTVLGCVVA
                     TMQAWQYNAVGIYLPVTLGGVLSGGLAGSLGGSALVNAAFGITGGLLGSLWVQRHGARK
                     LSMAGFAVVAASLLVLGALGSGAPWVALFLLGLIIFGHSAGPGGLGMTIATLSYPPSIR
                     PAGVGFARAIMRTGAIAGLVLWPMLWDALGTDAFFWLALVPATGLVTCLVIRWEPIGQP
                     VDDEDADVLRQITVTQRAA"
     gene            complement(1930..2943)
                     /locus_tag="LC193_RS00525"
                     /old_locus_tag="LC193_00525"
     CDS             complement(1930..2943)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1040: alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012335.5"
                     /locus_tag="LC193_RS00525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LC193_00525"
                     /product="zinc-binding dehydrogenase"
                     /protein_id="WP_226070172.1"
                     /sec_met_domain="ADH_N (E-value: 7.1e-28, bitscore: 95.1,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 5.8e-16, bitscore:
                     57.1, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTTVSRILFTAPGEVATETTEEPDAPLPAGHVRIAPQYLGICGS
                     DLHVLHGGHPFAKPPLVPGHELSAVVVETAPDVTGVAVGDRAVIDPIMACGACRACRAG
                     RPNLCEPPRVAGFRAPGFGRTSHIVPAANAHVAPASLPLDQLAFAEPVACAVHCLSRLR
                     DPADREDLLVIGAGTIGLTIVQALRVSGAGRLTVQEPDPAKRDLARRLGADVAVAPGEL
                     PEGAAFTAVIDVVAAQATLNEATTRVLPGGPVVVMGVPSGPREVPLPSMQRFERDLLGS
                     GMYVPGDFDTAIAWLADGRFRTDGLITDTFSLREAAAAYRRAAAPDSIKVLVRLAE"
     gene            complement(3033..3920)
                     /locus_tag="LC193_RS00530"
                     /old_locus_tag="LC193_00530"
     CDS             complement(3033..3920)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013916.5"
                     /locus_tag="LC193_RS00530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LC193_00530"
                     /product="hypothetical protein"
                     /protein_id="WP_226070181.1"
                     /transl_table=11
                     /translation="MTATTDRAAVLADIARPSGGFAMLAVDQREAMRLMFAAAGTAPVP
                     DQVLTDFKVKATEVLSPHASGVLVDRQFAYDAVLDAKAVHPDCGLIVAADAFLPGNGVP
                     VDAVAIDEDVDPAAVRARGGAALKLLVLWRQDEDPEERRAMVADFTARCRAAGLVSIIE
                     PVVRPPRRGWEFDREAAIVAAARELGDSGADLYKGEMPHGGDADDATLLSACRAIDDAV
                     SMPWVILSSGVEADLFGNAVRIACRAGASGFLAGRAVWKSVIGARNTEAVLRDVSVPRL
                     RRLADIVDEAVAAR"
     gene            complement(3949..4893)
                     /locus_tag="LC193_RS00535"
                     /old_locus_tag="LC193_00535"
     CDS             complement(3949..4893)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1276: PfkB domain protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012515.5"
                     /locus_tag="LC193_RS00535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LC193_00535"
                     /product="PfkB family carbohydrate kinase"
                     /protein_id="WP_226070183.1"
                     /transl_table=11
                     /translation="MSGTEAAVVCVGVVTLDALALVDRHPDADERVLAERVAITGGGPA
                     ATAAVVMARQGVRVSFVGRVGTDAEGEQAVELLAREGVDVSRVLRDPATATQSSVVLAA
                     SGTGTRCIATRAVPPLPALDGPAADLVAGADWVHTDHLGFAPVADLLERSARPGARRPA
                     LAVDAGNDVPGLDGRLGLVDLYVPTAASLTARYGATRTTSDALADCAARALAEGAGAVV
                     ATSGGEGSAAWWPGGGHAAAPAARGVEIVSTLGAGDVFHGALLAAVCRGLEWPEALRHA
                     NAAAALSCRALDGRGAVPDLAELTAFLAAAPAA"
     misc_feature    complement(4962..4976)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.38"
                     /tool="antismash"
     misc_feature    5040..5053
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: weak, score: 17.92"
                     /tool="antismash"
     misc_feature    5047..5064
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 15.6"
                     /tool="antismash"
     misc_feature    complement(5050..5063)
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: medium, score: 21.07"
                     /tool="antismash"
     gene            5121..5948
                     /locus_tag="LC193_RS00540"
                     /old_locus_tag="LC193_00540"
     CDS             5121..5948
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012669.5"
                     /locus_tag="LC193_RS00540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LC193_00540"
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="WP_226070185.1"
                     /transl_table=11
                     /translation="MPQDPLKYRAAPARRDEILDALRETGFLSIAEVAARLGVSEMTAR
                     RDIRRLAADAEVLAVRGGVVLPAGPRDRSAPAYSSRSAADVEEKRTVGRVAATCVRDDD
                     VIAVDAGTTAYQLAAALPDSFHGTVVTHSVPVIDLLMDRPSARGIALGGDLFAPSRALV
                     GSLTVDTAKRLKVRTFYLGAAGVDERGIYAAADVERQVKETLMDIAERVVLLIGRRKFT
                     TTAPVLLCGWDRLDAVVTDVEPPPPVHRTLEGNGVRLVLPTTEPATLRPPPAP"
     gene            complement(6024..6899)
                     /locus_tag="LC193_RS00545"
                     /old_locus_tag="LC193_00545"
     CDS             complement(6024..6899)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011031410.1"
                     /locus_tag="LC193_RS00545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LC193_00545"
                     /product="hypothetical protein"
                     /protein_id="WP_226070187.1"
                     /transl_table=11
                     /translation="MPLRTRRRRHAAMTGLLALATAAALATAPPAAAADTWTEVGSDRA
                     RPLTESQGLTSVEVPADSPNRYTGIGTIPADVSLRGWNHVGDPDASYDGHYIEPYQRDS
                     GGAKMFRVQAPDGSWAEYVHALGPGEALNNSWVAVSPDGQWMLAGEYGTMSRFLVFPTP
                     GANPATSPSADLPHVATVHLDRPVRDVQGCDFSGPTTLLCSSDDPAGTLFGMTKPLLQV
                     DLSAAPSGTADVSGQVTALRQLPLRSGCSGAFEAQGVDYDRRSGTLRVIVMSPGFCVLT
                     DSMTYRFTRG"
     gene            7166..7927
                     /locus_tag="LC193_RS00550"
                     /old_locus_tag="LC193_00550"
     CDS             7166..7927
                     /GO_function="GO:0005507 - copper ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0055070 - copper ion homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020551023.1"
                     /locus_tag="LC193_RS00550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LC193_00550"
                     /product="copper homeostasis protein CutC"
                     /protein_id="WP_226070189.1"
                     /transl_table=11
                     /translation="MSPRFEVCVDSARGALTAQDAGADRVELCGALSEGGLTPSAGLVE
                     TVLEAAREIEVFVLIRPRGGDFVYDAHEVRAMERDIETALALGAHGIVLGALTADAGVD
                     MAVCRRLLAATAGRPVTFHRAFDMARGPFDALERLVDLGVKRVLTSGQEVSALEGAPLL
                     ARLVRAAGNRLTVMPGGGVTERNVARVLRLTGAREIHFSAGTTVDGPMTHRNSRVLMGA
                     TLSRSEYARRLTSPEGVRGIMAAARAADTAG"
     gene            8154..9236
                     /locus_tag="LC193_RS00555"
                     /old_locus_tag="LC193_00555"
     CDS             8154..9236
                     /NRPS_PKS="Domain: PKS_ER (105-278). E-value: 6.3e-22.
                     Score: 70.0. Matches aSDomain:
                     nrpspksdomains_LC193_RS00555_PKS_ER.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028: crotonyl-CoA reductase / alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024989.5"
                     /locus_tag="LC193_RS00555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LC193_00555"
                     /product="alcohol dehydrogenase catalytic domain-containing
                     protein"
                     /protein_id="WP_226078423.1"
                     /sec_met_domain="ADH_N (E-value: 1.5e-20, bitscore: 71.5,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 1.4e-17, bitscore:
                     62.3, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MISTAVRVPSVTRSMVLRRFGDPETALELTERHPVPAPGRGEVLI
                     AVRAVSVGRTLDLATRAGLPPFAPQVRLPHVLGADHVGEVVAHGDGVDGPALGTRVAAF
                     PVVCCGRCDACAAGRTELCGGMELIGVHRPGAYAGYCRVPAANVRPVPEDMSDGAACAL
                     ALNGPVAHRQLEVAGVEPGDWVLVNGAAGGLGTALCAVALHRGLRVLACARQPWQREAL
                     RALGAQAALDPGADDFAAAVGSLTDGRGVAAVVDNLATRELAAALPAVLAPGGALVCSG
                     ALGAGTARLDLRALYLRSQRVLGVRTARLADVDATWAAAAGGLRPVVDERRAFGVEDAA
                     EAHRYLDEGRNFGRVVLAWS"
     aSDomain        8469..8987
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_LC193_RS00555_PKS_ER.1"
                     /evalue="6.30E-22"
                     /label="LC193_RS00555_PKS_ER.1"
                     /locus_tag="LC193_RS00555"
                     /protein_end="278"
                     /protein_start="105"
                     /score="70.0"
                     /tool="antismash"
                     /translation="VVCCGRCDACAAGRTELCGGMELIGVHRPGAYAGYCRVPAANVRP
                     VPEDMSDGAACALALNGPVAHRQLEVAGVEPGDWVLVNGAAGGLGTALCAVALHRGLRV
                     LACARQPWQREALRALGAQAALDPGADDFAAAVGSLTDGRGVAAVVDNLATRELAAALP
                     AVLAPGGALV"
     CDS_motif       8697..8753
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_LC193_RS00555_0001"
                     /evalue="1.10E-03"
                     /label="PKSI-ER_m5"
                     /locus_tag="LC193_RS00555"
                     /protein_end="200"
                     /protein_start="181"
                     /score="11.7"
                     /tool="antismash"
                     /translation="GDWVLVNGAAGGLGTALCA"
     CDS_motif       8883..8915
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_LC193_RS00555_0002"
                     /evalue="1.70E+01"
                     /label="PKSI-ER_m5"
                     /locus_tag="LC193_RS00555"
                     /protein_end="254"
                     /protein_start="243"
                     /score="-1.3"
                     /tool="antismash"
                     /translation="SLTDGRGVAAV"
     gene            complement(9282..10004)
                     /locus_tag="LC193_RS00560"
                     /old_locus_tag="LC193_00560"
     CDS             complement(9282..10004)
                     /GO_function="GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018384932.1"
                     /locus_tag="LC193_RS00560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LC193_00560"
                     /product="methyltransferase domain-containing protein"
                     /protein_id="WP_226070191.1"
                     /transl_table=11
                     /translation="MTTPLRDTTEYDEWSGQWWDPRGPFSTLSWIARQRASLIPRAPAG
                     TGGTPLLVDVCCGGGLLHPHIADKGYRHVGVDASALSAEVARSHGVDEVIHADVHRVPL
                     PDGCADVVVAGQCLEHVDRPWEVIAECCRLLKPGGLVIADTIADTLLARLAIITLAENV
                     PLSWMAPKGCHDHRMFVNPRRLAFEFARNGVPVQTYGLFPDKRDLLAWALNRTDRVRLR
                     RIASTDVIYQAIGRKPAA"
     gene            complement(10001..11908)
                     /locus_tag="LC193_RS00565"
                     /old_locus_tag="LC193_00565"
     CDS             complement(10001..11908)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T2TS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF024640.5"
                     /locus_tag="LC193_RS00565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LC193_00565"
                     /product="prenyltransferase/squalene oxidase
                     repeat-containing protein"
                     /protein_id="WP_226070192.1"
                     /sec_met_domain="T2TS (E-value: 1.8e-55, bitscore: 186.8,
                     seeds: 58, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDQSHKPNDAQVGAAVSAAVSAAFAAQAEDGAWPGEILTGGTSY
                     EAADIVMRTLLGATTPRHVEELAAWMLADQNEDGGWSLFRGGPSDLSSSAFTHIALQLA
                     GFPLDHEALRRAAAFVRSAGGLEAIDMVPVKFWLAFTGIVSWDEIPRVPPELVLLPSWV
                     PGALGDYEPMAREVVVAVGILTTVRPVRRLDVDVTVLRSGVPHPPSRAESVLTGTLRAV
                     HAATPRTLRAKALRAGEDWLMARQESDGSWGGSWTETLVCVLALWSRGYGIGHPVQRRA
                     LAACDELNVRVDGTRRVQTFRTVVMDSALMMSALDATGRTDVREPLRRAGRWLIDHRAD
                     TSVNTKGVRPLRAWDFEGIPTINADPDDTAMAITALRSAGASDGGADDEAVAATSEAAR
                     WLIACQSPSGGWAGFGVDRWSRLGEKALTGIGFVEGATACVTAHAVEALHAEGLGWHPG
                     CRRAVRWLLDAQDADGSWPSRWGVRLYGTSHVVSALRTAGAPADHPSIVAARRWLLEHQ
                     NPDGGWGENIALSLSDRRRATGESSAIHTAWCLRGLLRAGEVDEEAAAAAAGYLISHQN
                     EAGTWTDPTEWMIVIPDSVYISTPRMTHAFALWALADYQRHLSAVASGAAHPDQGKAAE
                     "
     gene            complement(11985..12524)
                     /locus_tag="LC193_RS00570"
                     /old_locus_tag="LC193_00570"
     CDS             complement(11985..12524)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0070967 - coenzyme F420 binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:TIGR03666.1"
                     /locus_tag="LC193_RS00570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LC193_00570"
                     /product="PPOX class F420-dependent oxidoreductase"
                     /protein_id="WP_226070194.1"
                     /transl_table=11
                     /translation="MSQERVRPLARPVAGRSLPGGRVADRLSLPPARILELLDAAYPAD
                     RAESARRVRETLARGKHALLITFRAGGGRVATPVWAAVEAERVYVRTQRASGKVARVGR
                     RPHVLLGVCSTRGRPLTGVVPATARVLPAGEERHAERLLHRRYGAVRAFCATAQDLMRV
                     DMCYLEITVGDDDPAG"
     gene            12772..13686
                     /locus_tag="LC193_RS00575"
                     /old_locus_tag="LC193_00575"
     CDS             12772..13686
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013226.5"
                     /locus_tag="LC193_RS00575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LC193_00575"
                     /product="prenyltransferase"
                     /protein_id="WP_226070196.1"
                     /transl_table=11
                     /translation="MDADVPPKPPAARESARIWVQAAGPPLVLVLVLQGAFAVTAVRHQ
                     GAVEWWRVALTVLLFVCDGIGRRLVNDFEDHRRGVDRPDRVRPDSSMALGLDMNRVRWA
                     GMGGFAAAWVCLLVLALTSEPLLLLVIPPMYAAYFAYAGGRRPLGHRGFGELLDFVVTG
                     TAVTLVVGRLNGDAFDAALWCAALACGFLFMTLMLHNNARDLAKDREAGKVTLPHLIPP
                     AAVKALYVTGLAGCYGFLALTALGLGAWGPLLPLVTLPWAALLAVRVCRGPLGTGMIDW
                     SGLYLLMLAVFATFTAGGWLPAW"
     gene            complement(13871..15457)
                     /locus_tag="LC193_RS00580"
                     /old_locus_tag="LC193_00580"
     CDS             complement(13871..15457)
                     /GO_function="GO:0046556 - alpha-L-arabinofuranosidase
                     activity [Evidence IEA]"
                     /GO_process="GO:0046373 - L-arabinose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019432016.1"
                     /locus_tag="LC193_RS00580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LC193_00580"
                     /product="non-reducing end alpha-L-arabinofuranosidase
                     family hydrolase"
                     /protein_id="WP_226070198.1"
                     /transl_table=11
                     /translation="MSHHHPAGGRPAPWRRLRALVALVVLALLATGMSATSAGPARAGA
                     APGAPAADHEPYVDTGAWYVLVNRNSGKALDVYNLATNDGARITQWSRNDQAQQRWQFV
                     DSGGGHYRLRSGHSGKVLDVHNWSTADGASVVQWSDHNTANQQFRLSEQGDGYVRLINR
                     HSGKALEVQGAATTDGANIVQYTDWGGANQQWRLVPVDGGEPPDSSLPSSFQWSSSGVL
                     AGPKSDASHDIVAIKDYSVVRHNGQWHVYATTASRSGGWNLVHFAAPDWSGMADARHTF
                     LDTASGVGTGYRAAPQVFYFAPQGLWYLVYQTGLPSYSVSSDPGDPGSWSAPRNFMDSM
                     PEIVRQNIGDGHWLDFWVICDAARCHLFSSDDNGHIYRAQTSLANFPRGFGDTVIALED
                     SNRNNLFEGSAVYRVGDTGTYLLLQEAIGSDGRRWYRSFTSTGLAGPWAPLAATESNPF
                     ARSNNVSFPSGAWTRDFSHGELIRANSDQTLTIDPCRLQFLYQGIDPGAGGEYSQLPWR
                     MGLLTQTNSAC"
     misc_feature    15673..15687
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 14.47"
                     /tool="antismash"
     misc_feature    complement(15750..15764)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 14.99"
                     /tool="antismash"
     misc_feature    15751..15764
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 12.7"
                     /tool="antismash"
     gene            15991..17040
                     /locus_tag="LC193_RS00585"
                     /old_locus_tag="LC193_00585"
     CDS             15991..17040
                     /EC_number="1.1.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_ER (21-297). E-value: 1.2e-14.
                     Score: 46.1. Matches aSDomain:
                     nrpspksdomains_LC193_RS00585_PKS_ER.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1040: alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007444294.1"
                     /locus_tag="LC193_RS00585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LC193_00585"
                     /product="NAD(P)-dependent alcohol dehydrogenase"
                     /protein_id="WP_226070199.1"
                     /sec_met_domain="ADH_N (E-value: 5e-31, bitscore: 105.2,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 3.9e-21, bitscore:
                     73.8, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSVRAYTATSAAGPLVPGVIERRDVGPRDVRIDIHWAGICHSDI
                     HTVRGDWGPVPYPLTVGHEIAGVVAEVGPEVTRYRVGDRVGVGCMVDSCRKCDNCRAGR
                     EQYCLAGFTDTYNGTDRDGSVTQGGYATGIVVDEHFVLRVPEAIPFEKAAPLLCAGITT
                     YSPLRRWNAGPGTKVAVVGMGGLGHMAVKIAHAMGAEVTVLSQTLGKREDGLRFGADHY
                     WATSDPATFKQLANTFDLIVNTVSAPLDLDAYLALLSFGGTIVSVGAPPEAVPVTLFTL
                     FENQRSFAGSKIGGIAETQEMLDFCAEHGIAPEVEIIPAERINEAWERVLSSDVRYRFV
                     IDAATLDAA"
     aSDomain        16054..16881
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_LC193_RS00585_PKS_ER.1"
                     /evalue="1.20E-14"
                     /label="LC193_RS00585_PKS_ER.1"
                     /locus_tag="LC193_RS00585"
                     /protein_end="297"
                     /protein_start="21"
                     /score="46.1"
                     /tool="antismash"
                     /translation="ERRDVGPRDVRIDIHWAGICHSDIHTVRGDWGPVPYPLTVGHEIA
                     GVVAEVGPEVTRYRVGDRVGVGCMVDSCRKCDNCRAGREQYCLAGFTDTYNGTDRDGSV
                     TQGGYATGIVVDEHFVLRVPEAIPFEKAAPLLCAGITTYSPLRRWNAGPGTKVAVVGMG
                     GLGHMAVKIAHAMGAEVTVLSQTLGKREDGLRFGADHYWATSDPATFKQLANTFDLIVN
                     TVSAPLDLDAYLALLSFGGTIVSVGAPPEAVPVTLFTLFENQRSFAGSKIGGIA"
     gene            17118..18038
                     /locus_tag="LC193_RS00590"
                     /old_locus_tag="LC193_00590"
     CDS             17118..18038
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018544109.1"
                     /locus_tag="LC193_RS00590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LC193_00590"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_226070201.1"
                     /transl_table=11
                     /translation="MSTKDEVREFLISRRANVSPEQAGLTGVGGERRVPGLRREEVAMI
                     AGVSPDYYTRLERGNIRGASESVLNAIARALQLNDVEREYLFDLARTAPAPARSRGGKP
                     ALRSVRASVQRVLDNLTLPALVHNANQDLIAANLMGRALYAPHYDTPHQPNIARFVFLD
                     PRAPDYYVDWPLARRTTAAIMRLEAGRDPLNGELTALIGELSTRSPLFRTDWAGHDVHS
                     HRTGVKSFRHPEVGVLDVSFDVFEMPGEAGLQIVTYSPAPGTRSADAFALLASWAATQG
                     PDSRRPGDGPEGRKARQDEAPRPAR"
     gene            complement(18123..21116)
                     /locus_tag="LC193_RS00595"
                     /old_locus_tag="LC193_00595"
     CDS             complement(18123..21116)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003971264.1"
                     /locus_tag="LC193_RS00595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LC193_00595"
                     /product="family 16 glycoside hydrolase"
                     /protein_id="WP_226070203.1"
                     /transl_table=11
                     /translation="MHARPRRHTAATLGVALVGALILPVAAAEAASRDDLPPQEPGVTL
                     RVFDVGFEPEEICTLTEGQTPNIDVLRPTVDWTSNEDFGGIANNFMGHVIGHLHVPEDG
                     TYHFRLISDDGSRLRLDGEEIIENDRRQPPTAADGSAELTAGAHALRIDYFQGAYDKAL
                     RLEWRPPGADAFGLVPESALTTDAGVTRVTSPGVKTCEDADASPGDGAPLAGVHPNYTL
                     TDLRPEGFEPKVTGMDWFDDGRMVITTWAGRETFDGAVEVVDGTLGEDAGPGRVTTEVV
                     ARDMNEPQGVLVEDGEVIVAEKHQLSRLVDAEGDGFYEAKETIATWPNGGTYHEFGFGL
                     LADEDHYYLNLSVAITPGGKTQVPQPAENRGTSVRIDKETGALDYVAGGLRTPNGIGWG
                     PGGDIFVTDNQGDWLPSSKLVAIEEGAFYNHYTNPPGPFDDQPVTEPVLWLPHGEIANS
                     PTNPVLVEEGVFEGQLVFGDVTYGGIQRAFLEEVEGQRQGAVFRMTQGLESGVSRLAIG
                     PDGSFYTGGIGGGGNWEQPGKVPYGLQKLTPTSEDAMDILSMEVTGTGFDITYTKPVAA
                     DVIENASERYAVEQWSYTPTSQYGGEKKNEEVLAVADASVSADGRTVSLDIPGLREDRV
                     VHVRSPRPFESADGTPLWSTEAWYTVHQIPGWVEPPNETGTYEAEDGELRGSADIDDEH
                     AHYTGGGYVDGFGDVGAELTWDVRVDEAGTYPVTFRYSNGPHPYAGTKTISLGVNGEDK
                     GQLAFESTGTWQTWADHVERLELRAGTNTITLSAGEDDDRHLNWDHLRVQQEPCAPARP
                     DEGYRVLFDGTQETFADWEMAAPGDFILQADCTMRSVGGLGLITHPEELTDYRLELDWK
                     MAGDDNSGVHIGLPDPAGDPEARNRGFEVQIDATDEPERTTGAIYDFQGADIAARDAAL
                     NPPGEWNSYAIEVEDLRVRVYLNDVLINEFDTEGADPDRDLGSGRVGLQNHHTGSDVWF
                     RDVRVRDL"
     misc_feature    complement(21048..21050)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(21392..21403)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 15.36"
                     /tool="antismash"
     misc_feature    21778..21792
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 14.63"
                     /tool="antismash"
     misc_feature    21825..21836
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 16.06"
                     /tool="antismash"
ORIGIN
        1 ctcggcgtgc tggggggtgc gccccagcgt gcaggcgacg aacgaggcgc cgtgcgccgt
       61 cacgcggtcc gccacgcggc gcgaggtggc cgggtcgacg gtcgacaggt ccacggcgac
      121 ggcgcccggc gcgaggtggg gcaggttgtc gccccagaat cccgcgacga gttccggcgt
      181 gggcagcgac gtgaacacca cgtcggccga ccgcaccgcg tccgcggcgt ccgccgccgc
      241 ctcggcgccc gcggccacgc acgcggcgac ggccgcgtgc gacaggtcga agacgcgtac
      301 gcggtggccg ccggacgcga ggcggcggca cacggcaccg cccatcgcgc ccgcgcccac
      361 gaagccgatg accggtccgt tgcgggtggt cctggacatg gggatctcct cgggacagaa
      421 ggtgggaagg ggaagctgag ggcgtccgcg cgcccgtcgc gtcaggccgc gcgttgcgtg
      481 acggtgatct gccgcaggac gtcggcgtcc tcgtcgtcca ccggctgccc gatgggctcc
      541 cagcggatga ccaggcaggt gacgaggccg gtggcgggga cgagggcgag ccagaagaag
      601 gcgtccgtgc cgagcgcgtc ccacagcatc ggccacagca ccagtcccgc gatggcaccg
      661 gtgcgcatga tggcccgggc gaagccgacc ccggccgggc ggatgctggg cgggtaggac
      721 agcgtggcga tggtcatgcc gagcccgccg ggtcccgccg agtggccgaa gatgatgagc
      781 ccgagcagga acagggccac ccagggggcg ccagacccca gcgcgccgag caccaggagc
      841 gaggccgcga cgaccgcgaa cccggccatg gagagcttgc gggcgccgtg gcgctgcacc
      901 cacagcgagc cgagcaggcc gccggtgatg ccgaaggccg cgttgacgag ggccgagccg
      961 cccaggctgc cggcgagccc tccggagagg acaccgccca gcgtcaccgg gaggtagatg
     1021 ccgaccgcgt tgtactgcca cgcctgcatg gtggcgacca cgcagcccag aacggtgcgc
     1081 cgccggtagg tgcggttgaa catgacccgg tacgcgccgc gcacccgggg gcgttccgag
     1141 ccgggggcgg cgccgaccgc gtcgtgggcg accacggcgt gcacgccgta gcgctcgcgc
     1201 aggatgcgca cggcctcgtc gtaccgctgc cggcgcgcgg cccacagggc cgactccccg
     1261 atgaagacgt agcgcagcac catgacgagc gcggcgaagg cggcgccgac gaagatgccg
     1321 taccgccaca ggtcggactc cacggaggtg gcctggtgca ggggcaggag gacgaggtac
     1381 acgacggtgg tcgatatgta ccagcccatc tgccacaggt tcaccgagcg gccggacttg
     1441 gagctcttgg agccggacag ctcgacgacc gccgaggtgg ccagggggaa gtcgatgccg
     1501 agcccgatgc ccatcaccac ccggcacagc aggacgaacc agatgctcgg ggcgaaggcc
     1561 accgccgccg cggcgacggt gcacagcccc atgcccagca ggaacgcgcg gcgctggccg
     1621 aggcgttcga tcaggggccg ggccatcagc ccgccgacga gggcggcgac gagcacggtg
     1681 gcgttcaccg cggcggcggc gcccgtgctg atgtcgtact cgtcggcgat gtaggagttg
     1741 ccgaagccga ccatggcggc ctggtaggcg tcgatcagca cgccgccgag ggcgatcagc
     1801 gcgacgcccg tgccgccccg cttggcgggg tggctgttga cgaggtcgac gacatcctgc
     1861 gggcggcgga tgacggccgg ttgtgaggtg ctcatgtgcg ttccacggtg cgtgcgtaag
     1921 ggcgggaggt tactcggcga gccgcacgag gaccttgatg gagtcgggtg cggcggcccg
     1981 ccggtaggcg gcggcggcct cccgcaggga gaacgtgtcg gtgatcaggc cgtccgtgcg
     2041 gaacctgccg tcggccagcc aggcgatcgc ggtgtcgaag tcgcccggga cgtacatgcc
     2101 ggagccgagg aggtcgcgtt cgaatcgctg catcgacggc agcgggacct cgcgggggcc
     2161 gctcggcacg cccatgacga cgacggggcc gccggggagg acccgggtgg tggcctcgtt
     2221 cagtgtggcc tgcgccgcca cgacgtcgat gaccgcggtg aacgcggcgc cctccggcag
     2281 ttcgccgggc gccacggcga catcggcgcc gagccggcgc gcgaggtccc gcttggccgg
     2341 gtcgggctcc tgcaccgtca gccgcccggc gccgctgacg cgcagcgcct ggacgatcgt
     2401 gaggccgatg gtcccggcgc cgatcacgag caggtcctcg cggtcggccg ggtcccgcaa
     2461 gcggctcagg cagtgcacgg cgcaggccac gggttccgcg aacgccagct ggtcgagcgg
     2521 cagcgaggcg ggcgcgacgt gcgcgttggc ggcgggcacg atgtgggagg tgcggccgaa
     2581 gccgggggcg cggaagccgg cgacccgcgg gggttcgcac aggttgggcc gcccggcgcg
     2641 gcacgcgcgg cacgcgccgc aggccatgat cgggtcgatg acggcccggt cgcccaccgc
     2701 gacgccggtg acgtcggggg cggtctcgac gacgaccgcg gacagctcgt ggcccggcac
     2761 gagcggcggc ttggcgaacg ggtgcccgcc gtgcaggacg tgcaggtcgc tgccgcagat
     2821 gccgaggtac tgcggcgcga tccgcacgtg gccggccggc agcggcgcgt ccggttcttc
     2881 ggtcgtctcg gtcgcgacct cgcccggggc ggtgaagagg atgcgggaaa cggtggtggt
     2941 catcgtgcgg gtacctccgg aagggggcgg ggcgccgggg cggccgggag cgcgggtcgg
     3001 ggggcgcgtc ccggccgccc cggcgggcgg ggtcagcggg cggcgaccgc ctcgtcgacg
     3061 atgtcggcga ggcggcgcag gcggggcacg gacacgtcgc gcagcaccgc ttcggtgttc
     3121 cgcgcgccga tcacggactt ccacacggcc cgcccggcga ggaatccgga cgccccggcg
     3181 cggcaggcga tgcgcacggc gttgccgaag agatcggcct cgacccccga ggagaggatc
     3241 acccagggca tcgacaccgc gtcgtcgatc gcccggcagg cgctcagcag ggtggcgtcg
     3301 tcggcgtcgc cgccgtgcgg catctcgccc ttgtacaggt cggcgccgct gtcgcccagt
     3361 tcccttgcgg cggccacgat cgccgcctcg cggtcgaact cccagccgcg ccgcggcggg
     3421 cgcaccaccg gttcgatgat gctgaccagg ccggcggcgc ggcagcgcgc ggtgaagtcc
     3481 gcgaccatcg cgcggcgctc ctcggggtcc tcgtcctgcc gccagagcac gaggagtttg
     3541 agcgcggcgc cgccgcgcgc gcggacggcg gccgggtcca cgtcctcgtc gatcgccacg
     3601 gcgtcgacgg ggacgccgtt gcccggcagg aaggcgtcgg cggccacgat caggccgcag
     3661 tccgggtgca cggccttggc gtcgaggacc gcgtcgtagg cgaactgccg gtccaccagc
     3721 acgcccgagg cgtggggcga gagcacctcg gtggccttca ccttgaagtc ggtgaggacc
     3781 tggtcgggca cgggcgccgt gccggccgcg gcgaacatca ggcgcatcgc ctcgcgctgg
     3841 tccaccgcga gcatcgcgaa gcccccggac gggcgggcga tgtcggccag cactgcggcc
     3901 ctgtcggtcg ttgcggtcat cggtgtccta ctccttcgag ggtgggggtc aggcggccgg
     3961 ggcggcggcc aggaaggcgg tcagctcggc caggtccggc acggcgccgc gcccgtcgag
     4021 agcgcggcag gacagggcgg cggcggcgtt ggcgtgccgc agcgcctcgg gccactccag
     4081 gccgcggcag acggcggcga gcagcgcgcc gtggaagacg tctcccgccc cgagggtgga
     4141 gacgatctcc actccccggg cggcgggggc ggcggcgtgc ccgccgcccg gccaccaggc
     4201 ggcgctgcct tcgccgccgc tggtggcgac gaccgccccg gcgccttccg cgagcgcgcg
     4261 ggcggcgcag tcggcgagcg cgtcggaggt ggtgcgcgtg gcgccgtagc gggcggtcag
     4321 cgaggcggcc gtcggcacgt acaggtcgac caggccgagt cggccgtcga ggccgggcac
     4381 gtcgttgccc gcgtcgacgg caagcgccgg gcggcgcgcc cccggccgtg ccgaccgctc
     4441 cagcaggtcg gcgacgggcg cgaaaccgag gtggtcggtg tgcacccagt ccgcgcccgc
     4501 gaccaggtcg gcggccgggc cgtcgagcgc gggcagcggc ggaacggcgc gggtggcgat
     4561 gcagcgggtg ccggtgccgg acgcggccag gaccacggac gactgggtgg cggtcgccgg
     4621 gtcgcgcagc acgcggctca cgtcgacgcc ctcgcgggcc agcagctcca cggcctgttc
     4681 gccctcggcg tccgttccca cgcggcccac gaaggagact cgcacgccct gccgggccat
     4741 gaccacggcc gcggtggccg ccgggccgcc gccggtgatg gccacccgtt ccgcgaggac
     4801 gcgctcgtcc gcgtccggat gccgatcgac gagcgcgagt gcgtcgaggg tcacgacccc
     4861 gacacacacc acggcggcct cagtcccgga cattcggtac ctcactgttc cgatacgaca
     4921 gagaaatgtt ctagaagcaa caacacattg actcgatcaa caataatctg tcaagtagcg
     4981 aacaacatgg ccgagggcgc gacgctgggg acggccggtc gcacggctgc gcccgggcgg
     5041 aaaagtttgt tagattcgtt tcaaaccgcg cccggcggcg gcctcgcctc cgcccgcccc
     5101 cgatccgcga cgaggtagcc gtgccgcaag atccgctgaa gtaccgggcg gcccccgctc
     5161 gccgcgacga gatcctcgac gcgttgcgcg agacgggttt cctgtccatc gcggaggtcg
     5221 cggcccggct cggcgtctcc gagatgaccg cccgccgcga catccgccgg ctcgccgccg
     5281 acgcggaggt gctcgccgtg cggggcggcg tggtgctgcc cgccggtccc cgcgaccgct
     5341 ccgcgcccgc ctacagcagc cgctccgccg cggacgtcga ggagaagcgc accgtcggcc
     5401 gggtcgccgc cacctgcgtg cgcgacgacg acgtgatcgc cgtggacgcg ggcaccaccg
     5461 cgtaccagct ggccgccgcg ctgcccgact cgttccacgg caccgtggtc acccactccg
     5521 tgccggtgat cgacctgctc atggaccggc cgagcgcacg gggcatcgcg ctcggcggcg
     5581 acctgttcgc ccccagccgc gcgctcgtcg gctcgttgac cgtggacacc gccaagcgcc
     5641 tgaaggtccg caccttctac ctgggggcgg cgggcgtgga cgagcgcggg atctacgccg
     5701 ccgccgacgt cgaacggcag gtgaaggaaa ccctgatgga catagccgaa cgggtcgtcc
     5761 tgctcatcgg gcggcggaag ttcacgacca ccgctcccgt actgctgtgc ggctgggacc
     5821 ggctggacgc cgtcgtgacg gatgtcgagc ccccgccccc ggtgcaccgc acgcttgagg
     5881 gcaacggcgt gcgcctcgtg ctgcccacca cggagcccgc caccctgcga ccacccccgg
     5941 ccccgtgacc ggccgccgcc cgccaccggc acggcgccgc gcgccccgcc cgccgtcgcg
     6001 ggccgggcgc gcggcgcggt acgtcagccg cgcgtgaagc ggtacgtcat gctgtcggtc
     6061 agcacgcaga agcccggtga catgacgatg acgcgcagcg tgccgctgcg ccggtcgtag
     6121 tcgacgccct gcgcctcgaa cgcgccggag cagccgctgc gaagcgggag ctgccgcagc
     6181 gcggtgacct gccccgagac gtcggccgtt ccgctgggcg cggcggagag gtcgacctgg
     6241 agcagcggct tggtcatgcc gaacagggtg cccgccgggt cgtcggacga gcacagcagc
     6301 gtcgtcggac ccgagaagtc gcagccctgg acgtcgcgca cgggccggtc gaggtggacg
     6361 gtggccacgt gcgggaggtc ggccgagggc gaggtggccg ggttggcgcc cggggtcggg
     6421 aagaccagga accggctcat cgtgccgtac tcgcccgcga gcatccactg gccgtcgggc
     6481 gagacggcga cccaggagtt gttgagcgcc tcgccggggc cgagggcgtg cacgtactcc
     6541 gcccagctcc cgtcgggcgc ctgcacgcgg aacatcttgg caccgcccga gtcccgctgg
     6601 tacggctcga tgtagtggcc gtcgtaggag gcgtcggggt cgccgacgtg gttccagccg
     6661 cgcagggaga catcggcggg aatggtgccg atgccggtat agcggttggg gctgtcggcc
     6721 ggcacctcga ccgaggtcag gccctgactt tcggtcagcg gccgggcgcg gtcggagccg
     6781 acctcggtcc aggtgtccgc cgccgcggcg ggcggcgcgg tggcgagggc ggcggcggtg
     6841 gcgagggcga gcaggccggt catggccgcg tggcgccgtc gccgggtgcg caggggcatg
     6901 aggggtccgt tcgtcggtgg gggcggggga cgcgttcgac cggacggtac gacgcggacg
     6961 gtagccatgt acagaccaat gaggggaacg gcagccgacg gccggatgac cgcccgcggc
     7021 cctcgcccgc ccgccgcgcg ccgcgacgcg gcccttaccc tggtccacgg tccccgcacc
     7081 gaacccgcgc aggaagcccc ggtcgcacga tgagccacgc acccgcaccc gcccctcgcc
     7141 tcacccgcgc cccggcggaa cgccgatgag cccgcgcttc gaggtctgcg tcgactccgc
     7201 gcgcggcgcg ctgaccgccc aggacgccgg cgccgaccgc gtggagctgt gcggcgcgct
     7261 gtccgagggc ggcctcacgc cgagcgcggg cctggtggag acggtgctgg aggcggcgcg
     7321 ggagatcgag gtgttcgtgc tgatccgccc gcgcggcggt gacttcgtct acgacgccca
     7381 cgaagtgcgc gccatggaac gggacatcga gacggcgctc gccctcggcg cccacgggat
     7441 cgtcctgggc gcgctgacgg ccgacgcggg cgtcgacatg gcggtgtgcc gcaggctgct
     7501 ggccgcgacc gccggccgcc cggtgacctt ccaccgggcg ttcgacatgg cccggggccc
     7561 cttcgacgcc ctggagcggc tggtcgacct cggcgtcaag cgcgtcctca cctcgggcca
     7621 ggaggtctcg gccctggaag gcgcgccgct gctcgcccgg ctggtccggg cggcggggaa
     7681 ccgcctcacc gtgatgccgg gcggcggcgt gacggaacgc aacgtggccc gcgtgctgcg
     7741 tctcaccggc gcgcgggaga tccacttcag cgccggcacc acggtcgacg gcccgatgac
     7801 gcaccgcaac tcccgcgtcc tcatgggcgc gacgctgagc aggagcgagt acgcgcgccg
     7861 gctcaccagc ccggaagggg tccgggggat catggccgcc gcccgcgccg ccgacaccgc
     7921 cggctgaccc cgcgcccgct cccgcgtcgg cccgggcgcg ggcggcggtc ccgcggacgc
     7981 ggggagccca cgtgccgacc tgctcccagg cggcagcagt tgaacgcttc cgtccggccg
     8041 gcgcacccgc gccggcggcc ccggtcgggc accggactcc ccggccgccg cggggccgtt
     8101 gaacgccctg gcggacgccg gccgggcggc gacaggatga ccgggtgaag gacatgatct
     8161 cgaccgccgt gcgcgtaccc tctgtcaccc gctccatggt gctgcgccgc ttcggagacc
     8221 cggagacggc actcgaactg accgagcggc accccgttcc cgcaccgggc cggggggagg
     8281 tgctgatcgc ggtgcgggcc gtgagcgtcg ggcggaccct cgacctcgcc acgcgggccg
     8341 ggctgccgcc gttcgccccg caggtgcggc tgccgcacgt gctcggcgcc gaccacgtcg
     8401 gggaggtggt cgcccacggg gacggggtgg acggacccgc gctcggcaca cgggtcgccg
     8461 ccttccccgt cgtctgctgc gggcggtgcg acgcgtgtgc cgcgggcagg acggaactgt
     8521 gcggcggcat ggagctgatc ggcgtgcacc ggcccggcgc gtacgccggg tactgccgcg
     8581 tgcccgcggc caacgtgcgg cccgtgcccg aggacatgtc cgacggcgcg gcctgcgccc
     8641 tggcactcaa cgggccggtg gcgcaccggc agttggaggt cgccggggtg gagccgggcg
     8701 actgggtcct ggtcaacggg gccgccggcg gcctcggcac ggcgctgtgc gcggtggcgc
     8761 tccaccgcgg gctgcgggtg ctcgcctgtg cccggcagcc gtggcagcgg gaggcgctgc
     8821 gggcgctggg cgctcaggcc gcgctcgacc ccggcgccga tgacttcgcc gccgcggtcg
     8881 ggtcgctgac ggacggcagg ggcgtggccg cggtcgtcga caacctggcc acccgggaac
     8941 tggccgccgc cctgcccgcc gtgctggcac ccggcggtgc cctggtgtgc tcgggcgcgc
     9001 tcggggcggg cacggcgcgc ctcgacctgc gcgcgctcta cctgcgcagc cagcgcgtgc
     9061 tcggcgtgcg gaccgccagg ctcgcggacg tggacgcgac atgggcggcg gcggccggcg
     9121 gcctgcggcc ggtggtggac gaacggcggg cgttcggcgt cgaggacgcc gccgaggcgc
     9181 atcgctacct ggacgagggc cgcaacttcg gccgggtcgt gctggcgtgg agctgacgcg
     9241 ccgccgggcc cggcctgtgc cgccgggccc ggagggatgg ctcaggcggc cggcttgcgg
     9301 ccgatggcct ggtagatgac gtcggtcgag gcgatgcggc gcagcctgac ccggtcggtg
     9361 cggttcagcg cccaggccag gaggtcgcgc ttgtcgggga agagcccgta ggtctggacg
     9421 ggcaccccgt tcctggcgaa ctcgaacgcg agccgcctcg ggttgacgaa catccggtgg
     9481 tcgtggcacc ccttgggcgc catccagctc aacggcacgt tctcggccag ggtgatgatg
     9541 gccagccgcg ccagcagcgt gtccgcgatg gtgtccgcga tcacgagtcc gcccggcttg
     9601 agcaggcggc agcactcggc gatcacctcc caggggcggt ccacgtgctc caggcactgc
     9661 ccggccacca cgacgtccgc gcacccgtcg ggcagcggca cgcggtggac gtccgcgtgg
     9721 atcacctcgt ccacgccgtg gctgcgggcg acctcggcgc tgagcgcgga cgcgtccacg
     9781 cccacgtgcc ggtacccctt gtccgcgatg tgcgggtgga gcaggccgcc gccgcagcag
     9841 acgtccacga gcagaggcgt cccgccggtg cccgcgggcg cccggggaat gagggaggcc
     9901 cgctgcctgg cgatccagga gagcgtggag aagggaccgc gcgggtccca ccactgcccc
     9961 gaccactcgt cgtactcggt cgtgtcgcgc aagggggtgg tcattccgct gcctttccct
    10021 ggtccgggtg cgccgcgccc gacgcgaccg ccgagaggtg gcgctggtag tcggcgagcg
    10081 cccacagggc gaacgcgtgg gtcatcctcg gcgtgctgat gtacacgctg tccgggatga
    10141 cgatcatcca ctccgtgggg tcggtccagg tgccggcctc gttctggtgg gagatcaggt
    10201 acccggccgc ggccgcggcg gcctcctcgt ccacctcgcc ggcccgcagc aggccgcgca
    10261 ggcaccaggc ggtgtggatg gcgctgctct cgccggtcgc gcggcggcgg tcgctgaggc
    10321 tgagggcgat gttctcgccc cagccgccgt cggggttctg gtgttcgagc agccagcggc
    10381 gggcggccac gatcgacgga tggtccgccg gggcgccggc cgtgcgcagc gcggagacga
    10441 cgtggctcgt tccgtacagc ctgacgcccc agcgcgacgg ccacgaaccg tcggcgtcct
    10501 gcgcgtcgag cagccagcgc acggcgcggc ggcagccggg gtgccagccc aggccctcgg
    10561 cgtgcagggc ctcgacggcg tgggcggtga cgcaggcggt ggccccctcg acgaatccga
    10621 tgccggtgag cgccttctcg ccaagacgcg accagcggtc caccccgaag ccggcccagc
    10681 cgcccgaggg ggactggcac gcgatcagcc agcgcgcggc ctccgaggtc gcggccaccg
    10741 cctcgtcgtc cgcgccgccg tcggaggcgc cggcggaccg cagggcggtg atggccatgg
    10801 ccgtgtcgtc cgggtcggcg ttgatcgtcg gaatgccctc gaagtcccag gcgcgcaggg
    10861 gccgtacgcc cttggtgttg acggaggtgt cggccctgtg gtcgatgagc cagcggcccg
    10921 cgcggcgcag cggctcccgt acgtcggtgc ggccggtggc gtccagggcc gacatcatga
    10981 gcgcggagtc catcacgacg gtgcggaacg tctgcacccg ccgcgtgccg tccacccgga
    11041 cgttcagctc gtcgcaggcg gcgagcgcgc ggcgctgcac ggggtgcccg atgccgtagc
    11101 cgcggctcca cagcgccagc acgcagacca gggtctccgt ccagctgccg ccccagctgc
    11161 cgtccgactc ctgccgggcc atcagccagt cctcgcccgc ccgcagggcc ttggcgcgca
    11221 gcgtcctcgg cgtcgccgcg tgcaccgcgc gcagggtgcc ggtcagcacg gactcggccc
    11281 gggacggcgg gtgggggacg ccgctgcgca gcacggtgac gtccacgtcg aggcggcgca
    11341 ccggcctgac ggtcgtcagg atgcccacgg cgacgacgac ctccctggcc atcggctcgt
    11401 agtcgccgag cgcgccgggg acccaggagg gcagcagcac cagttccggc ggcacgcggg
    11461 ggatctcgtc ccagctcacg atgcccgtga aggcgagcca gaacttcacc ggcaccatgt
    11521 cgatcgcctc aaggccgccc gcggaccgca cgaaggccgc ggcccggcgc agcgcctcgt
    11581 ggtcgagcgg gaacccggcc agttgcaggg cgatgtgggt gaaggcactg ctcgacaggt
    11641 cggaggggcc gccgcggaac agggaccagc cgccgtcctc gttctggtcc gcgagcatcc
    11701 aggcggcgag ttcctcgacg tgccgcgggg tcgtggcacc gagcagggtg cgcatcacga
    11761 tgtcggcggc ctcgtaggag gtcccgcccg tgaggatctc ccccggccag gcgccgtcct
    11821 ccgcctgggc ggcgaaggcg gcggagacgg cggccgagac ggccgccccc acctgcgcgt
    11881 cgttcggctt gtgcgattgg tctgtcacca ctgttccttg cgttgcgttc tcgcggtctt
    11941 cgcggttctg gtggttctcc cggctgccac cgcgccgccc gcggtcaccc ggccgggtcg
    12001 tcgtccccga cggtgatctc caggtagcac atgtcgaccc gcatcaggtc ctgggcggtc
    12061 gcgcagaacg cccgcaccgc cccgtacctg cggtgcagca ggcgttcggc atgccgttcc
    12121 tcgcctgcgg gcaggacccg ggcggtggcg ggcaccacgc cggtcagggg gcgcccgcga
    12181 gtggagcaca cgccgagcag cacgtgcggg cggcggccga cgcgggcgac cttccccgag
    12241 gcgcgctggg tccgcacgta cacccgctcg gcctccaccg cggcccacac gggggtggcg
    12301 acgcgaccgc caccggccct gaaggtgatc agcagcgcgt gcttgccgcg cgcgagcgtc
    12361 tcgcggacgc ggcgcgcgct ctcggcgcgg tcggccgggt acgcggcgtc gaggagttcg
    12421 aggatgcggg ccgggggcag gctgagccgg tcggcgacgc gcccgcccgg caggctgcgg
    12481 ccggccaccg gccgggccag aggacgtaca cgctcctggg acacaccact ccttctcccg
    12541 cccccgggag gggacttgcg acgccgccgc atcgtacggg ctcgcggagc ggcctggcga
    12601 cgcgcgcgtt caaccgctcc tgcccgcccc ggcggatgtt gcccgcggac ggacgggtgg
    12661 ggaaagctga ccccccgccg tcggagccgc gttgccccgg tcgaggcggt cccgatgcac
    12721 gatccgagaa tccgagaatc cgagaacctg agaaagaggc ggccgttgcg gttggatgcc
    12781 gacgttcctc cgaagccacc cgccgcgcgg gagtcggcgc ggatctgggt gcaggcggcg
    12841 ggaccgccgc tggtcctcgt gctggtcctc cagggggcgt tcgccgtgac ggccgtgcgc
    12901 caccagggcg ccgtcgagtg gtggcgcgtc gcgctcacgg tgctcctgtt cgtctgcgac
    12961 ggaatcggcc ggcgcctggt gaacgacttc gaggaccaca ggcggggcgt ggacaggccc
    13021 gaccgggtgc gccccgacag ctcgatggcg ctcggtcttg acatgaaccg ggtgcggtgg
    13081 gccggcatgg gcgggttcgc ggcggcgtgg gtctgcctcc tcgtcctcgc gctcacctcc
    13141 gagcccttgc tgctgctggt gatcccgccg atgtacgcgg cctacttcgc ctacgccggc
    13201 gggcggcgcc cgctcggcca ccggggcttc ggcgagctgc tcgacttcgt ggtcaccggc
    13261 acggccgtga cgctggtcgt cgggcggctc aacggtgacg cgttcgacgc cgccctctgg
    13321 tgcgcggcgc tcgcctgcgg gttcctgttc atgacgctga tgctgcacaa caacgcccgc
    13381 gacctggcca aggacaggga ggcgggcaag gtcaccctgc cgcacctgat cccgcccgcg
    13441 gcggtgaagg cgctgtacgt caccggcctc gccggctgct acgggttcct ggcgctgacg
    13501 gcgctcggtc tcggggcgtg gggtccgctg ctgcccctgg tgacgctgcc gtgggcggcc
    13561 cttctcgccg tccgggtgtg ccgggggccg ctgggcaccg gcatgatcga ctggtcgggg
    13621 ctgtacctgc tgatgctcgc ggtcttcgcg accttcacgg cgggcggctg gctcccggcc
    13681 tggtgaccgc ggcgccccgg ccccggcccg ttcccgccgg tgcgcggctg agccggtgcg
    13741 cggggagtgg gggcggtcct gtgagggtgg cgacgcgccg gtgccccagg tctcggcggc
    13801 gcggggcgga ccgctcggtc atcgggcggc ccgccccttc gtcatgcccg ccactggggc
    13861 ccggcctgcc tcagcaggcg gagttggtct gggtgagcag gcccatgcgc cagggcagtt
    13921 ggctgtactc gccgcccgcg ccggggtcga tgccctggta gaggaactgg aggcggcagg
    13981 ggtcgatggt gagtgtctga tcgctgttcg ccctgatcag ctccccgtgg ctgaagtccc
    14041 gggtccacgc gcccgagggg aaggacacgt tgttcgaccg ggcgaagggg ttcgactcgg
    14101 tcgcggccag cggagcccac gggccggcga ggccggtgga ggtgaaggag cggtaccagc
    14161 ggcggccgtc ggagccgatg gcctcctgga gcagcaggta ggttccggtg tccccgaccc
    14221 tgtacaccgc gctgccctcg aagaggttgt tgcggttgga gtcctcaagg gcgatgacgg
    14281 tgtcgccgaa gccgcggggg aagttcgcca gggaggtctg ggcccggtag atgtggccgt
    14341 tgtcgtcgct ggagaacagg tggcagcggg ccgcgtcgca gatgacccag aagtcgagcc
    14401 agtggccgtc gccgatgttc tgccggacga tctccggcat gctgtccatg aagttgcgcg
    14461 gcgccgacca ggacccgggg tcgccggggt cgctgctgac cgagtacgag ggcagtcccg
    14521 tctggtagac caggtaccac agtccctgcg gggcgaagta gaacacctgg ggcgcggcgc
    14581 ggtacccggt gccgacgccg gacgcggtgt cgaggaaggt gtgcctggca tcggccatcc
    14641 ccgaccagtc gggggccgcg aagtgcacca ggttccagcc gccgctccgg ctcgcggtgg
    14701 tggcgtacac gtgccactgg ccgttgtgcc ggacgaccga gtagtccttg atggcgacga
    14761 tgtcgtggct cgcgtccgac ttcggaccgg ccagcacgcc gctcgaactc cactggaacg
    14821 acgagggcag cgacgagtcg ggcggctcgc cgccgtcgac gggcaccagc cgccactgct
    14881 ggttggcccc gccccagtcg gtgtactgga cgatgttcgc gccgtcggtg gtcgcggctc
    14941 cctgcacctc aagcgccttg ccgctgtggc ggttgatcag gcgcacgtac ccgtcgccct
    15001 gctcggacag ccggaactgc tggttggcgg tgttgtggtc cgaccactgg acgacggacg
    15061 cgccgtcggc ggtggaccag ttgtggacgt cgaggacctt ccccgagtgc ccggacctca
    15121 gccggtagtg gcccccgccc gagtcgacga actgccaccg ctgctgcgcc tgatcgttgc
    15181 gcgaccactg cgtgatgcgc gccccgtcgt tcgtcgccag gttgtacacg tccagcgcct
    15241 tgccgctgtt gcggttcacg agcacgtacc aggcgccggt gtcgacgtac ggctcgtggt
    15301 cggccgccgg cgctcccggc gcggcgccgg cccgggccgg gccggcggac gtcgccgaca
    15361 tgccggtggc caggagcgcc aggacgacca gtgcgaccag tgctctcagc cgtcgccacg
    15421 gcgcgggccg tccgcccgcc ggatggtggt gactcatctg tcgtccctcc tgcgagaacg
    15481 atgtgcaagc gctcccggac ggcctcgacc gtcatccgga agccggacac gcggtgcacg
    15541 gcgcccggcg ggtcgccgcc ggcggcggcc agtaccgggc gtggtttcgg gcagctcggc
    15601 gcaaacgtgc ggtacgggtg gggcggaagt gacgagggag ccaattccgt tcgccatgcc
    15661 ggacgttggc cggtttttca gacgagatac gaccaagata ggcgtcggcg gcccgacgtc
    15721 aacacctctc actcccatca gtttcgagga attccaagaa aagatcggtc gcggcagcgg
    15781 acagcgtccg gccgagagac gaccgggagg cggtcgccac caaccgccgc tcagggtgtg
    15841 aggggccctc tcagggcctc ccggaggccg ggcggagggt ggttccctgg agcgtgacgg
    15901 cgctccgccg ccgttcgcgc cggcacgggg gcgaggcccc ggtccaccgg cgcggcaagg
    15961 ttttccatga tcgtcttcgc aaggacagca atgacttccg tacgcgctta caccgccact
    16021 tccgccgcag gaccgctggt ccccggagtg atcgagcggc gcgacgtggg cccgagggac
    16081 gtgcgcatcg acatccactg ggccggaatc tgccactccg acatccacac cgtccgcggc
    16141 gactggggtc cggtgcccta cccgctgacg gtcgggcacg agatcgccgg cgtggtcgcc
    16201 gaggtcggcc ctgaggtcac gcggtaccgg gtcggcgacc gggtgggggt cggctgcatg
    16261 gtcgactcct gccggaagtg cgacaactgc cgcgcgggcc gcgagcagta ctgcctggcg
    16321 ggcttcaccg acacctacaa cgggaccgac cgcgacggaa gcgtcacgca gggcggttac
    16381 gccaccggga tcgtcgtgga cgagcacttc gtgctgcgcg tccccgaggc catcccgttc
    16441 gagaaggccg ccccgctgct gtgcgccggc atcacgacct actcgccgct gcgccgctgg
    16501 aacgccggcc cgggcacgaa ggtcgcggtc gtcggcatgg gcgggctcgg gcacatggcg
    16561 gtcaagatcg cccacgccat gggtgccgag gtgacggtcc tctcgcagac cctcggcaag
    16621 cgcgaggacg ggctgcgctt cggcgcggac cactactggg ccaccagcga cccggcgacg
    16681 ttcaagcagc tggcgaacac cttcgacctc atcgtcaaca ccgtcagcgc cccgctggac
    16741 ctggacgcct acctggcgct gctgtcgttc ggcggcacca tcgtcagcgt cggcgccccg
    16801 ccggaggccg tgcctgtgac gttgttcacg ctgttcgaga accagcggtc cttcgccggt
    16861 tcgaagatcg gcggcatcgc cgagacccag gagatgctcg atttctgcgc agagcacggc
    16921 atagcccccg aggtcgagat catcccggcg gagcggatca acgaggcgtg ggagcgggtg
    16981 ctgtcctccg acgtccgcta ccggttcgtg atcgacgccg cgacgctcga cgccgcctga
    17041 cggcggccgg cccccgggcg cgccgcgggc gcccgggggc accccgaccg accgcggacc
    17101 ggatctacgg tggagtcatg agcacgaagg atgaggtgag ggagttcctg atctcccgcc
    17161 gcgcgaacgt gtcccccgag caggcgggcc tcaccggcgt cggcggggag cggcgcgtcc
    17221 ccgggctgcg ccgcgaggag gtggcgatga tcgccggggt gagcccggac tactacacgc
    17281 gtcttgagcg cggcaacatc cgcggcgcct cggagagcgt gctcaacgcc atcgcgcgcg
    17341 ccctccagct caacgatgtg gagcgcgagt acctgttcga cctggcccgc accgccccgg
    17401 cgcccgccag gtcgcgcggc gggaagcccg ccctgcgctc ggtgcgggcc tcggtccagc
    17461 gggtgctcga caacctgacg ctgccggccc tcgtgcacaa cgcgaaccag gacctgatcg
    17521 cggccaacct catgggccgc gccctgtacg cgccgcacta cgacaccccg caccagccga
    17581 acatcgcccg tttcgtcttc ctcgaccccc gcgcccctga ctactacgtc gactggccgc
    17641 tggcccgccg caccacggcg gcgatcatgc gccttgaggc cgggcgcgac ccgctgaacg
    17701 gcgagctgac cgcgctcatc ggggagctgt ccacccgcag tccgctgttc cgcacggact
    17761 gggccggcca cgacgtgcac tcccaccgca ccggagtgaa gtcgttccgg caccccgagg
    17821 tcggtgtcct cgacgtgtcg ttcgacgtgt tcgagatgcc gggcgaggcg ggcttgcaga
    17881 tcgtgaccta cagccccgcc ccgggaacgc ggtccgcgga cgcgttcgcg ctgctggcgt
    17941 cctgggccgc gacccagggg ccggacagcc ggcggccggg cgatggcccc gagggccgga
    18001 aggcccgcca ggacgaggcg ccccgcccgg cccggtgacg cccggcgccg ggagggcgga
    18061 cacggtaccg cgtgtccgcc ctcccgctgc tcaccctccg gcgcgtgcgc cgcgcgccgc
    18121 cgtcacaggt ccctcacccg cacatcgcgg aaccagacgt cggaaccggt gtggtggttc
    18181 tgcaacccga cgcgtcccga gccgaggtcc cggtcggggt cggcgccctc ggtgtcgaac
    18241 tcgttgatca gcacgtcgtt gaggtacacc ctgacgcgca ggtcctcgac ctcgatcgcg
    18301 tagctgttcc actcccccgg cgggttcagc gccgcgtccc tggccgcgat gtcggcgccc
    18361 tggaagtcgt agatcgcgcc ggtcgtgcgc tcgggctcgt ccgtcgcgtc gatctgcacc
    18421 tcgaaccccc ggttgcgcgc ctcggggtcg ccggccgggt ccggcaggcc gatgtgcacg
    18481 ccggagttgt cgtccccggc catcttccag tccagttcga gacggtagtc ggtcagttcc
    18541 tccgggtggg tgatcagccc gagtccgccg acggaccgca tggtgcagtc ggcctggagg
    18601 atgaagtcac cgggagcggc catctcccag tcggcgaacg tctcctgggt gccgtcgaac
    18661 agcacgcggt agccctcgtc cggccgggcg ggggcgcagg gctcctgctg gacgcgcagg
    18721 tggtcccagt tcagatgccg gtcgtcgtcc tcccccgcgg agagggtgat ggtgttcgtc
    18781 cccgcgcgca gttcgagccg ctcgacatga tcggcccatg tctgccaggt cccggtgctc
    18841 tcgaacgcca gctgcccctt gtcctcgccg ttgacgccga gcgagatcgt cttggtgccg
    18901 gcgtacgggt gggggccgtt ggaatagcgg aaggtcaccg ggtaggtgcc ggcctcatcg
    18961 acgcgcacgt cccaggtcag ctccgcgccg acgtcgccga acccgtccac gtagcccccg
    19021 cccgtgtagt gcgcgtgctc gtcgtcgatg tccgcggagc cgcgcagctc cccgtcctcg
    19081 gcctcgtacg tgccggtctc gttgggcggc tcgacccagc cggggatctg gtgaacggtg
    19141 taccaggcct cggtgctcca cagcggggtg ccgtcggcgg actcgaacgg ccgcggcgag
    19201 cgcacgtgca cgacccggtc ctcgcgcagc cccgggatgt ccaggctcac cgtgcgcccg
    19261 tcggcggaga ccgaggcatc cgcgacggcc aggacctcct cgttcttctt ctccccgccg
    19321 tactgcgagg tcggggtgta cgaccactgc tccaccgcgt accgctcgct cgcgttctcg
    19381 atcacgtccg ccgcgaccgg cttggtgtac gtgatgtcga acccggtccc cgtgacctcc
    19441 atcgacagga tgtccatggc gtcctcggac gtgggcgtca gcttctggag cccgtagggg
    19501 accttgcccg gctgctccca gttgccgcca ccgccgatgc cgcctgtgta gaacgagccg
    19561 tccgggccga tcgcgagacg gctgacgccc gattcgagcc cctgggtcat ccggaagacc
    19621 gcgccctgcc gctgcccttc gacctcctca aggaacgccc gctggatgcc gccgtaggtg
    19681 acgtcgccga agaccagctg cccctcgaac acgccctcct cgaccagcac cggattggtc
    19741 ggcgagttcg ctatctcgcc gtgcggcagc cacagcaccg gctcggtgac cggctggtcg
    19801 tcgaacggcc ccggcgggtt cgtgtagtgg ttgtagaacg ccccctcctc gatcgcgacc
    19861 agcttcgacg agggcagcca gtcgccctgg ttgtccgtca cgaagatgtc gccgccgggc
    19921 ccccagccga tgccgttcgg ggtgcgcagg ccgccggcga cgtagtcgag cgcgccggtc
    19981 tccttgtcga tccggaccga ggtgccgcgg ttctcggcgg gctgggggac ctgggtcttg
    20041 ccgcccgggg tgatggccac cgacaggttc aggtagtagt ggtcctcgtc ggccaggaga
    20101 ccgaacccga actcgtggta ggtaccgccg ttgggccagg tcgcgatggt ttccttggcc
    20161 tcgtagaagc cgtcgccttc ggcgtcgacc agcctgctga gctggtgctt ctccgcgacg
    20221 atcacctcgc cgtcctcgac gagcacgccc tgcggctcgt tcatgtccct cgcgacgacc
    20281 tcggtggtga ccctcccggg tcccgcgtcc tctccgaggg tgccgtcgac gacctcgacg
    20341 gcgccgtcga aggtctccct gcccgcccag gtggtgatga ccatgcggcc gtcgtcgaac
    20401 cagtccatgc cggtgacctt cggctcgaac ccctcgggcc gcaggtcggt cagcgtgtag
    20461 ttcgggtgga ccccggcgag cggcgccccg tcccccgggc tcgcgtcggc gtcctcgcag
    20521 gtcttcaccc cgggcgaggt cacgcgggtg acgccggcgt cggtggtcag cgcggactcg
    20581 ggcacgagcc cgaacgcgtc cgcgcccggc ggcctccact ccaggcgcag cgccttgtcg
    20641 taggcgccct ggaagtagtc tatgcgcagg gcgtgggcgc ccgcggtcag ctcggccgag
    20701 ccgtcggccg ccgtcggcgg ctggcgccgg tcgttctcga tgatctcctc gccgtcgagg
    20761 cgcagccggg agccgtcgtc actgatgagg cggaagtggt aggtgccgtc ctcgggcacg
    20821 tggagatggc cgatcacatg gcccatgaag ttgttggcga tgccgccgaa atcctcgttc
    20881 gacgtccagt cgacggtcgg ccgcaggaca tcgatgttcg gcgtctgccc ctcggtcagg
    20941 gtgcagatct cctccggctc gaatccgacg tcgaagaccc ggagtgtgac gcccggctcc
    21001 tggggcggca ggtcgtcccg cgacgcggcc tcggccgcgg ccaccggtaa gatcagcgcg
    21061 ccgaccaggg cgacccccag ggtcgccgcc gtatggcgac gtggccttgc atgcatggaa
    21121 ccgactcctt cgcgcggctc ggggcaattc cgttcttcgt gcggtgcgcg tttcgccggg
    21181 ggcgggcagg acgccgttcc acgggcgtgc ggattgccgt ttcccggcgt gggacctcac
    21241 gtcccggcgg cgtggcgagg ctcgggcgaa cccggaaaaa ggggaaatac ggcaggggga
    21301 accacgccat gggccaccgc tgccgcgcgg cggactccgc ccttctcgaa cgtttcctgg
    21361 tgcccgactc gcgatcgcac ggcggccggg cataaacgtt gtcttttgca gggaaattag
    21421 ggtttccgtg gattcctgtc aacacggcga gcgacgcgaa agacgaaacg cgttgcgaca
    21481 atccactgga gaacccccca taccggcacg ggccgccgac ccatgcgccc gcccgcacga
    21541 ggccgcacgt ccaccgcgcc gcgccggtgt gacttatcac ctgcgcgggt ggcgcggccg
    21601 acgggcccgg ccggacgcgg ccgcgttgcg ctacaagggc tccatgacga caaggcgccg
    21661 gttccgcgcc gcggtggcca ccgcgtccgc cgttcgtgct ttccgcacgg ccgcgccggg
    21721 ggccgcgcgc acggacccgg ggcgccggga gggagaccgg tgacgggatt cggcaggtat
    21781 ttcgaggaat ttgaggtcgg cgcggtctac cggcactggc cggggaaaac ggtgaccgaa
    21841 tacgaccacc acttgttctc cctgctcacc atggtgcggc atcccctgca caccgacgcc
    21901 cactacgc
//
