LOCUS       NZ_CP071043            21612 bp    DNA     linear   CON 13-NOV-2023
DEFINITION  Bacillus subtilis isolate ELA2001105 chromosome.
ACCESSION   NZ_CP071043
VERSION     NZ_CP071043.1
KEYWORDS    RefSeq.
SOURCE      Bacillus subtilis
  ORGANISM  Bacillus subtilis
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
REFERENCE   1  (bases 1 to 4089676)
  AUTHORS   Tawari,N.R., Mane,S.P., Susanti,D., Volland,A. and Kumar,A.
  TITLE     Multi-omic analyses and microbiological characterizations of
            animal-origin Bacillus spp. as an alternative to antibiotic growth
            promoter to improve growth performance in broiler chicken
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 4089676)
  AUTHORS   Tawari,N.R., Mane,S.P., Susanti,D., Volland,A. and Kumar,A.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-FEB-2021) Global Computational Sciences, Elanco Animal
            Health, 3rd Cross, Murugeshpallya, Bangalore, Karnataka 560017,
            India
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 28-JAN-2020
            Assembly Method                   :: HGAP v. 3
            Genome Coverage                   :: 126.45X
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 11/13/2023 05:04:14
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,241
            CDSs (total)                      :: 4,120
            Genes (coding)                    :: 4,006
            CDSs (with protein)               :: 4,006
            Genes (RNA)                       :: 121
            rRNAs                             :: 10, 10, 10 (5S, 16S, 23S)
            complete rRNAs                    :: 10, 10, 10 (5S, 16S, 23S)
            tRNAs                             :: 86
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 79 of 114
            Pseudo Genes (incomplete)         :: 48 of 114
            Pseudo Genes (internal stop)      :: 19 of 114
            Pseudo Genes (multiple problems)  :: 26 of 114
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 08:27:42
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 3710873
            Orig. end                         :: 3732485
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP071043.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Annotated at Elanco.
FEATURES             Location/Qualifiers
     region          1..21612
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="sactipeptide"
                     /region_number="11"
                     /rules="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /tool="antismash"
     cand_cluster    1..21612
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /kind="single"
                     /product="sactipeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21612
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:11612](+)"
                     /cutoff="20000"
                     /detection_rule="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /neighbourhood="10000"
                     /product="sactipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11612
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /neighbourhood="10000"
                     /product="sactipeptide"
                     /protocluster_number="1"
     misc_feature    complement(107..121)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 20.21"
                     /tool="antismash"
     gene            complement(199..3884)
                     /gene="narG"
                     /locus_tag="JS609_RS19210"
                     /old_locus_tag="JS609_03777"
                     /pseudo=""
     CDS             complement(199..3884)
                     /GO_component="GO:0009325 - nitrate reductase complex
                     [Evidence IEA]"
                     /GO_function="GO:0008940 - nitrate reductase activity
                     [Evidence IEA]"
                     /GO_process="GO:0009061 - anaerobic respiration [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="narG"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391609.2"
                     /locus_tag="JS609_RS19210"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="JS609_03777"
                     /product="nitrate reductase subunit alpha"
                     /pseudo=""
                     /transl_table=11
                     /translation="MKKKKMSPLFRRLNYFSPIEHHSNKHSQTTREDRDWENVYRNRWQ
                     YDKVVRSTHGVNCTGSCSWNIYVKNGIVTWEGQNLNYPSTGPDMPDFEPRGCPRGPVFH
                     GISTARSV"
     misc_feature    complement(3950..3965)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: strong, score: 19.26"
                     /tool="antismash"
     misc_feature    complement(3974..3987)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 21.07"
                     /tool="antismash"
     misc_feature    3974..3988
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 21.64"
                     /tool="antismash"
     gene            complement(4080..4556)
                     /gene="arfM"
                     /locus_tag="JS609_RS19215"
                     /old_locus_tag="JS609_03779"
     CDS             complement(4080..4556)
                     /codon_start=1
                     /gene="arfM"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391610.1"
                     /locus_tag="JS609_RS19215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JS609_03779"
                     /product="Crp/Fnr family transcriptional regulator ArfM"
                     /protein_id="WP_003243032.1"
                     /transl_table=11
                     /translation="MNQCDYLLFLKQLPMFNEVPLSIVETLLKNGTFIRGSCDQSPSFL
                     HSQSVYIVLKGSVRFMDTRLPEGSKTVALWEKGDVFPIDEKGGLYLSPFISVNATSDIL
                     ILNIPYYIFKKMMSYHPQLQMNFLAMLQQNVFCSYQLFLRYLHTSQDENAEPGS"
     misc_feature    complement(4619..4634)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 17.4"
                     /tool="antismash"
     gene            4705..5424
                     /gene="ywiC"
                     /locus_tag="JS609_RS19220"
                     /old_locus_tag="JS609_03780"
     CDS             4705..5424
                     /codon_start=1
                     /gene="ywiC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391611.1"
                     /locus_tag="JS609_RS19220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JS609_03780"
                     /product="YwiC-like family protein"
                     /protein_id="WP_213414798.1"
                     /transl_table=11
                     /translation="MKALIPKQHGAWAMLLIPFLLGMVKGGPVIWHIPLFLGWLFLYLA
                     VYPVTLALKKNQSKPYQKWMCYYGFPACCFLMISVFHKPPLIWVGVSLLPLFLIHMYFA
                     RRKKERALLNDVAGVLFFCSGGFASCWLGMGTLDGWAWFIFLQSALFFIGSSFYVKSVI
                     RERKNRTFAYWSWGYHLLLPFLSALFGAGWAFLAFIPSSLRAWFFHGRDWPVKTIGILE
                     IVNACFFLAVMCLFITR"
     gene            complement(5455..6171)
                     /gene="fnr"
                     /locus_tag="JS609_RS19225"
                     /old_locus_tag="JS609_03781"
     CDS             complement(5455..6171)
                     /codon_start=1
                     /gene="fnr"
                     /gene_functions="regulatory (smcogs) SMCOG1133:
                     Transcription regulator, crp"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391612.1"
                     /locus_tag="JS609_RS19225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JS609_03781"
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="WP_213414797.1"
                     /transl_table=11
                     /translation="MNFLSVRPSDSDHISSDLYELLESISTKRKMEKHTYLFREGMDAE
                     ELYLIQSGLIEIGKLTSDGKDLTLRICQKHDIVGELTLFTEEPRYMLSAKVLEDGEVLV
                     INKNKLEKELIQNGALTFEFMKWMSTHLRKIQSKIRDLLLHGKKGALYSTLIRLSNSYG
                     VERSDGILINIVLTNQDLAKFCAAARESINRMLGDLRKKGVISIDESGKIILHKRDYLR
                     CEIECENCPLEICNID"
     gene            complement(6270..7457)
                     /gene="narK"
                     /locus_tag="JS609_RS19230"
                     /old_locus_tag="JS609_03782"
     CDS             complement(6270..7457)
                     /codon_start=1
                     /gene="narK"
                     /gene_functions="transport (smcogs) SMCOG1106: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391613.2"
                     /locus_tag="JS609_RS19230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JS609_03782"
                     /product="nitrate/nitrite transporter"
                     /protein_id="WP_213414796.1"
                     /transl_table=11
                     /translation="MINRQHIQLSLQSLSLVAGFMVWVLISSLISQITLDIHLSKGEIS
                     LVTAIPVILGSLLRIPLGYLTNRFGARLMFMVSFILLLFPVFWISIADSLFDLIAGGFF
                     LGIGGAVFSIGVTSLPKYYPKEKHGVVNGIYGAGNIGTAVTTFAAPVIAQAVGWKSTVQ
                     MYLILLSVFALLHVLFGDRHEKKVKVSVKTQIKAVYRNHVLWFLSLFYFITFGAFVAFT
                     IYLPNFLVEHFGLNPADAGLRTAGFIAVSTLLRPAGGFLADKMSPLRILMFVFAGLTLS
                     GIILSFSPTIGLYTFGSLTVAVCSGVGNGTVFKLVPFYFSKQAGIANGIVSAMGGLGGF
                     FPPLILASVFQATGQYAIGFMALSEVALASFVLVIWMYWQERMKTHTERNSQSIN"
     misc_feature    complement(7522..7537)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: strong, score: 19.26"
                     /tool="antismash"
     gene            complement(7593..9263)
                     /gene="argS"
                     /locus_tag="JS609_RS19235"
                     /old_locus_tag="JS609_03783"
     CDS             complement(7593..9263)
                     /EC_number="6.1.1.19"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0004814 - arginine-tRNA ligase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006420 - arginyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="argS"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391614.1"
                     /locus_tag="JS609_RS19235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JS609_03783"
                     /product="arginine--tRNA ligase"
                     /protein_id="WP_015250994.1"
                     /transl_table=11
                     /translation="MNIAEQMKDVLKEEIKAAVLKAGLAEESQIPNVVLETPKDKTHGD
                     YSTNMAMQLARVAKKAPRQIAEEIVAHFDKGKASIEKLDIAGPGFINFYMNNQYLTKLI
                     PSVLEAGEAYGETNIGNGERVQVEFVSANPTGDLHLGHARGAAVGDSLCNVLSKAGYDV
                     SREYYINDAGNQINNLALSVEVRYFEALGLEKPMPEDGYRGEDIIAIGKRLAEEYGDRF
                     VNEEESERLAFFREYGLKYELDKLRKDLENFRVPFDVWYSETSLYQNGKIDTALEALRE
                     KGHVYEEDGATWFRSTTFGDDKDRVLIKKDGTYTYLLPDIAYHKDKLDRGFDKLINVWG
                     ADHHGYIPRMKAAIEALGYEKGTLEVEIIQLVHLYKNGEKMKMSKRTGKAVTMRDLIEE
                     VGLDAVRYFFAMRSADTHMDFDLDLAVSTSNENPVYYAQYAHARICSMLRQGEEQGLKP
                     AADLDFSHIQSEKEYDLLKTIGGFPEAVAEAAEKRIPHRVTNYIYDLASALHSFYNAEK
                     VIDPENEEKSRARLALMKATQITLNNALQLIGVSAPEKM"
     gene            complement(9260..9688)
                     /gene="ywiB"
                     /locus_tag="JS609_RS19240"
                     /old_locus_tag="JS609_03784"
     CDS             complement(9260..9688)
                     /codon_start=1
                     /gene="ywiB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391615.1"
                     /locus_tag="JS609_RS19240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JS609_03784"
                     /product="DUF1934 domain-containing protein"
                     /protein_id="WP_003243604.1"
                     /transl_table=11
                     /translation="MKQETPITLHVKSVIEDDGNQEVIEFRTTGFYYVKQNKVYLSYYE
                     EHDLGKVKTIVKVSEGEVLVMRSGAVKMNQRFVTGASTIAKYKMSFGELELKTSTKSIQ
                     SDLDEEKGRISIAYDMHVGDEQEHLHNMTITYEGGTHA"
     misc_feature    9895..9910
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: medium, score: 25.99"
                     /tool="antismash"
     gene            10001..10132
                     /gene="sboA"
                     /locus_tag="JS609_RS19245"
                     /old_locus_tag="JS609_03785"
     CDS             10001..10132
                     /GO_process="GO:0019835 - cytolysis [Evidence IEA]"
                     /codon_start=1
                     /gene="sboA"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     sactipeptide: Subtilosin_A"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391616.1"
                     /locus_tag="JS609_RS19245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JS609_03785"
                     /product="subtilosin A"
                     /protein_id="WP_003222002.1"
                     /sec_met_domain="Subtilosin_A (E-value: 8.9e-29, bitscore:
                     97.4, seeds: 2, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKAVIVENKGCATCSIGAACLVDGPIPDFEIAGATGLFGLWG"
     CDS_motif       10001..10030
                     /prepeptide="leader"
                     /note="peptide class: sactipeptide"
                     /note="predicted sequence: MKKAVIVENK"
                     /locus_tag="JS609_RS19245_sactipeptide"
                     /aSTool="sactipeptides"
                     /tool="antismash"
     CDS_motif       10031..10132
                     /prepeptide="core"
                     /locus_tag="JS609_RS19245_sactipeptide"
                     /peptide="sactipeptide"
                     /predicted_class
                     /score="33.00"
                     /molecular_weight="0.0"
                     /monoisotopic_mass="0.0"
                     /core_sequence="GCATCSIGAACLVDGPIPDFEIAGATGLFGLWG"
                     /aSTool="sactipeptides"
                     /tool="antismash"
                     /leader_sequence="MKKAVIVENK"
                     /leader_location="[10000:10030](+)"
     gene            10089..10241
                     /gene="sboX"
                     /locus_tag="JS609_RS19250"
     CDS             10089..10241
                     /codon_start=1
                     /gene="sboX"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_054594.1"
                     /locus_tag="JS609_RS19250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="bacteriocin-like protein SboX"
                     /protein_id="WP_010886632.1"
                     /transl_table=11
                     /translation="MKLPVQQVYSVYGGKDLPKGHSHSTMPFLSKLQFLTKIYLLDIHT
                     QPFFI"
     gene            10266..11612
                     /gene="albA"
                     /locus_tag="JS609_RS19255"
                     /old_locus_tag="JS609_03786"
     CDS             10266..11612
                     /codon_start=1
                     /gene="albA"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     sactipeptide: subtilosin"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Subtilosin_rSAM_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PTHR43273"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) QueE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR04085"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SPASM"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391617.1"
                     /locus_tag="JS609_RS19255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JS609_03786"
                     /product="subtilosin maturase AlbA"
                     /protein_id="WP_015714887.1"
                     /sec_met_domain="subtilosin (E-value: 0.0, bitscore:
                     1083.7, seeds: 6, tool: rule-based-clusters)"
                     /sec_met_domain="Subtilosin_rSAM_RRE (E-value: 5e-29,
                     bitscore: 98.4, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 3.3e-07, bitscore: 28.4,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="PTHR43273 (E-value: 1.1e-44, bitscore:
                     150.8, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="QueE (E-value: 3.5e-06, bitscore: 24.6,
                     seeds: 32, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 5.3e-22, bitscore: 76.9,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 5.2e-10, bitscore:
                     37.5, seeds: 281, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 1.6e-09, bitscore: 36.0,
                     seeds: 166, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFIEQMFPFINESVRVHQLPEGGVLEIDYLRDNVSISDFEYLDLN
                     KTAYELCMRMDGQKTAEQILAEQCAVYDESPEDHKDWYYDMLNMLQNKQVIQLGNRASR
                     HTITTSGSNEFPMPLHATFELTHRCNLKCAHCYLESSPEALGTVSIEQFKKTADMLFDN
                     GVLTCEITGGEIFVHPNANEILDYVCKKFKKVAVLTNGTLMRKESLELLKAYKQKIIVG
                     ISLDSVNSEVHDSFRGRKGSFAQTCKTIKLLSDHGIFVRVAMSVFEKNMWEIHDMAQKV
                     RDLGAKAFSYNWVDDFGRGRDIVHPTKDAEQHRKFMEYEQNVIDEFKDLIPIIPYERKR
                     AANCGAGWKSIVISPFGEVRPCALFPKEFSLGNIFHDSYESIFNSPLVHKLWQAQAPRF
                     SEHCMKDKCPFSGYCGGCYLKGLNSNKYHRKNICSWAKNEQLEDVVQLI"
     aSDomain        10281..10556
                     /aSDomain="Subtilosin_rSAM_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing rSAM protein in a subtilosin
                     sactipeptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_JS609_RS19255_Subtilosin_rSAM_RRE.1"
                     /evalue="3.40E-31"
                     /identifier="RREFam018.1"
                     /label="JS609_RS19255"
                     /locus_tag="JS609_RS19255"
                     /protein_end="97"
                     /protein_start="5"
                     /score="98.4"
                     /tool="antismash"
                     /translation="MFPFINESVRVHQLPEGGVLEIDYLRDNVSISDFEYLDLNKTAYE
                     LCMRMDGQKTAEQILAEQCAVYDESPEDHKDWYYDMLNMLQNKQVIQ"
     gene            11625..11786
                     /gene="albB"
                     /locus_tag="JS609_RS19260"
                     /old_locus_tag="JS609_03787"
     CDS             11625..11786
                     /codon_start=1
                     /gene="albB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391618.1"
                     /locus_tag="JS609_RS19260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JS609_03787"
                     /product="antilisterial bacteriocin subtilosin biosynthesis
                     protein AlbB"
                     /protein_id="WP_003222006.1"
                     /transl_table=11
                     /translation="MSPAQRRILLYILSFIFVIGAVVYFVKSDYLFTLIFIAIAILFGM
                     RARKADSR"
     gene            11783..12502
                     /gene="albC"
                     /locus_tag="JS609_RS19265"
                     /old_locus_tag="JS609_03788"
     CDS             11783..12502
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene="albC"
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391619.1"
                     /locus_tag="JS609_RS19265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JS609_03788"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_017696261.1"
                     /transl_table=11
                     /translation="MSILDIHDVSVWYERDNVILEQVDLHLEKGAVYGLLGVNGAGKTT
                     LINTLTGVNRNFSGRFTLCGIEAEAGMPQKTSDQLKTHRYFAADYPLLFTEITAKDYVS
                     FVHSLYQKDFSEQQFASLAEAFHFSKYINRRISELSLGNRQKVVLMTGLLLRAPLFILD
                     EPLVGLDVESIEVFYQKMREYCEAGGTILFSSHLLDVVQRFCDYAAILDNKQIQKVIPI
                     GEETDLRREFFEVIGHE"
     gene            12495..13805
                     /gene="albD"
                     /locus_tag="JS609_RS19270"
                     /old_locus_tag="JS609_03789"
     CDS             12495..13805
                     /codon_start=1
                     /gene="albD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391620.1"
                     /locus_tag="JS609_RS19270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JS609_03789"
                     /product="antilisterial bacteriocin subtilosin biosynthesis
                     protein AlbD"
                     /protein_id="WP_038829818.1"
                     /transl_table=11
                     /translation="MNNIIPIMSLLFKQLYSRQGKKDAIRIAAGLVILAVFEIGLIRQA
                     GIDESVLRKTYIILALLLMNAYMVFLSVTSQWKESYMKLSCLLPISSRSFWLAQSVVLF
                     VDTCLRRTLFFFILPLFLFGNGTLSGAQTLFWLGRFSFFTVYSIIFGVVLSNHFVKKKN
                     LMFLLHAAIFACVCISAALMPAATLPLCAVHMLWAVIIDFPVFLQAPPQQSKMHSFMRR
                     SEFSFYKREWNRFISSKAMLLNYAVMAAFSGFFSFQMMNTGIFNQQVVYIVISALLLIC
                     SPIALLYSIEKNDRMLLITLPIKRKTMFWAKYRFYSGLLAGGFLLVVMIVGFISGRPIS
                     VLTFLQCIELLLAGAFIRLTADEKRPSFSWQTEQQLWSGFSKYRSYLFCLPLFLATLAG
                     TAVSLAVIPIAGLVIVYYLQKQDGGFFDTSKRERLGS"
     gene            13795..14955
                     /gene="albE"
                     /locus_tag="JS609_RS19275"
                     /old_locus_tag="JS609_03790"
     CDS             13795..14955
                     /codon_start=1
                     /gene="albE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M16_C"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391621.1"
                     /locus_tag="JS609_RS19275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JS609_03790"
                     /product="antilisterial bacteriocin subtilosin biosynthesis
                     protein AlbE"
                     /protein_id="WP_080015532.1"
                     /sec_met_domain="Peptidase_M16_C (E-value: 5.3e-05,
                     bitscore: 21.2, seeds: 139, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEVNLLKTHQFSTISIAASFLKPIESAAEPEEETIYFYGAAAYLK
                     EQIIDAFGCAAGSRFMYSANLFFDQQLKTCGTRLIHPLYNGNLHVDALLKTFADLSFPS
                     SLSFEAVEKARNELLLRIEKKFTDPFSYSAARLAEEVFGNPMYGTGMFGRKDRIKAIHP
                     KRFLDATDFIVDLVSQQKQLNILGQVQACDVRGHAPQTSAVTSERIPVNRHVFETETRS
                     AAGPSVLTLGFDCGEMKDASDYIKIQLIDGLLGKYGHSALFKHFREKDLAVYHVITRYD
                     VMNNLLLVSICTDQLHEIDIPPRVLEAVSAFHTDERELEQAKQFLRNELLLQFDSPEGL
                     LAYMGILRRFSCTKEALLDGISAVTCRDVLQFIATINYIGAHVVRG"
     gene            14960..16240
                     /gene="albF"
                     /locus_tag="JS609_RS19280"
                     /old_locus_tag="JS609_03791"
     CDS             14960..16240
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="albF"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M16"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391622.1"
                     /locus_tag="JS609_RS19280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JS609_03791"
                     /product="pitrilysin family protein"
                     /protein_id="WP_029318696.1"
                     /sec_met_domain="Peptidase_M16 (E-value: 2.5e-13, bitscore:
                     48.2, seeds: 24, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKKAFFQQLDERTDIRYTDSGLKIFRLKFPRAHLRLCNVKIDFG
                     SRDVCIRAESGDTLLPYGTAHFLEHLLFWHNGRNLYSDFFAHGALLNAFTTYTDTNFMF
                     TSLPDRLRQTIPILLDALWNHSFDKKIVAQEKAVITSEIQTAHLNHQLSYHYQLISMLS
                     PSSPAAVFPAGRIEDIEALDISDLQKAYKAAYQAHRMTLFLIGGSENTETLLPPHLQLE
                     KRPDYHAERKIIPACPPALSQKMVLGDEERMEDTWTGLQIGALPGQNDLLAIKLYWDIA
                     ARILFQLDSPFFQEIQQTYRLEIDRLSAETYIYEDGGFLILHSQGTHSSAYIDVASYYV
                     TQKKEQVAAWLQYGKDSLTDAIIYDSDYVRKCFEWAAECDRCDCSFLDMYHIIQDMDAQ
                     VFLSLIDAMASSNKAIIHVSQKEAIRQ"
     gene            16237..16938
                     /gene="albG"
                     /locus_tag="JS609_RS19285"
                     /old_locus_tag="JS609_03792"
     CDS             16237..16938
                     /codon_start=1
                     /gene="albG"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391623.1"
                     /locus_tag="JS609_RS19285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JS609_03792"
                     /product="antilisterial bacteriocin subtilosin biosynthesis
                     protein AlbG"
                     /protein_id="WP_225722130.1"
                     /transl_table=11
                     /translation="MKKSTVFTLLLLLIGMAAYSFGWVQAVAEAAAQYVQMINNDAVRL
                     GLLACTAALLMLPAFLYLHYVTQSVKNMTAAFQKLTQSHQSCCDFQQHNLCSRYAEDVK
                     SLRDSYKNVRQTYVMAAVLCQVIIFGCMFEIVKAVPFRLHTPPALSMGLAMLLILYLLF
                     CMRTYLRQLFRHGSLFRKVFAGALAAAGIWWILSFSISELLFLIILATIQQIGSFIYKR
                     FSYRSTASLDL"
     gene            complement(16944..18320)
                     /gene="ywhL"
                     /locus_tag="JS609_RS19290"
                     /old_locus_tag="JS609_03793"
     CDS             complement(16944..18320)
                     /codon_start=1
                     /gene="ywhL"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391624.1"
                     /locus_tag="JS609_RS19290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JS609_03793"
                     /product="YncE family protein"
                     /protein_id="WP_041351296.1"
                     /transl_table=11
                     /translation="MKKNDLSALQENCFCFCDEEISREAPFQVPIDIPEGFKVDSAEAS
                     AAVTWSTDNVSCISEPCLIQTGPEPEDIGVRYAVRVQGTITLLVSVSPVRNQYGQGNGA
                     VSVIHTEEIDQVVYYAAQSGRCPDFSQITVEDLLIVPPFYGSPLTVTGTLVLPPSPDPQ
                     SYVFTANTGDSTVSVIDADLNTVVKTIPFSDVPTNLGVTFDKAFTYVLHGNTNLVSVID
                     NKTLTIINTITVGGGPRKIEFDPKDEFAYVMAAGSIYVINTASQSVIDVIPIPGALDFA
                     LDPNGQYVYTANGSSWSVDKYDINTGQLVESIIDTFEFPSLIATPYAGNFAYVLNGELW
                     PKGVTEISLSPLSRGGDFSRLFETLRTIVFSLDSTRAYFLEPYSEPFLINNLYVVNTAR
                     QRIIANVSLPGAFDLAVTPDKQYIYAAQPNDNAVTVYRTSDYTAVTVIPVGAGPSAIAM
                     "
     misc_feature    18287..18304
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 21.71"
                     /tool="antismash"
     gene            complement(18359..19714)
                     /gene="ywhK"
                     /locus_tag="JS609_RS19295"
                     /old_locus_tag="JS609_03794"
     CDS             complement(18359..19714)
                     /codon_start=1
                     /gene="ywhK"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391625.1"
                     /locus_tag="JS609_RS19295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JS609_03794"
                     /product="YncE family protein"
                     /protein_id="WP_225722131.1"
                     /transl_table=11
                     /translation="MRKNKLSFKEKAGAEQEECLCFCEGEASREAMFQAPIELPEGFVV
                     DPAEAVANVTWNADSLSCVSDRCLIQTGPEPDEIGVQFAVRLQGTVTLLVSVSPVRNQY
                     GQGDGAVSVIHNAEIDQVVYYSDEPDDCPDISDITIENLVVVPPFYGSPLSVTGTIVLV
                     PEPEPVYAFTANPNDQSVSVIDTNTHSVVTTIALPYNPAGIEITPDKSAVFVLHPNNNV
                     ISVIDYDTLTVTATILLDQPPRLIRFIPNHEFAYVFTGTAIYVIGIDTLTVERSIPVEG
                     FDIAIDPNGLFAYVLNFGLVQKVDLSTGEVLGTIERELIVSSIETDSTERYAYVLEQEF
                     LFNYLTVIDLNTFTIRDTQELEPDGLYVMFTSGSEVYLHDSFTGNLYSVSPNGAGVIGN
                     LPQSATDYAFTPNGDFLYATRFIEQSIIVYNTDDYSEETVISLGVSPGAITI"
     gene            complement(19711..19941)
                     /locus_tag="JS609_RS21240"
     CDS             complement(19711..19941)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009968328.1"
                     /locus_tag="JS609_RS21240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_033883387.1"
                     /transl_table=11
                     /translation="MQIPPFIILYMSYFIINILVRSAKKPQFFLSLHRMFGDIFSKRSV
                     YPQQFVQANTLHFHILLYLREQCMSEKEVKE"
     misc_feature    19895..19911
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 22.81"
                     /tool="antismash"
     gene            19944..21089
                     /locus_tag="JS609_RS19300"
                     /old_locus_tag="JS609_03795"
     CDS             19944..21089
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391626.1"
                     /locus_tag="JS609_RS19300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JS609_03795"
                     /product="tetratricopeptide repeat protein"
                     /protein_id="WP_213414789.1"
                     /transl_table=11
                     /translation="MTGVISSSSIGEKINEWYMYIRRFSIPDAEYLRREIKQELDQMEE
                     DQDLHLYYSLMEFRHNLMLEYLEPLEKMRIEEQPRLSDLLLEIDKKQARLTGLLEYYFN
                     FFRGMYELDRREYVLAIQFFKKAESKLVFVKDKIDKAEFFFKMSEVYYYMKQTYVSMDY
                     ARQAFEIYSEQTTYDIRMIQCQSLFGANFLDLKQYEKAIAHFQKAFTLAKTEQKPQLMG
                     RTLYNIALCKQNQNSFESAIEYVKKSIQVFEGSKMLPSLPQAFFLITQIYFKLGKIDNA
                     CEYHKKGKEYSAAAGDTVYLTEFEFLESLYLSGPDEERIEKCFVFLESKMMYADIEDFA
                     LDVAKYYHQQENYKKASHYFLKVEEARQHIQGGVNLYEMEV"
     gene            21073..21192
                     /locus_tag="JS609_RS19305"
                     /old_locus_tag="JS609_03796"
     CDS             21073..21192
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003326489.1"
                     /locus_tag="JS609_RS19305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JS609_03796"
                     /product="PhrC/PhrF family phosphatase-inhibitory
                     pheromone"
                     /protein_id="WP_014665774.1"
                     /transl_table=11
                     /translation="MKWKYKLLLACLAVSAVFITVEVSNSSTEHFDVAQRAMI"
ORIGIN
        1 tttttcaatg tccagccgcc tttatatttg tcctggtcct cccattgctt cgggtagccg
       61 atgcccggct ttgtttctac attattgaag tacatatatt ccgcaccgga acggtttgtc
      121 cacgtgtttt tgcaggtgac gctgcacgtg tggcagccga tgcatttatc caagttcatg
      181 accataccga tttgcgcttt aatcttcaag ccaatcgacc tccttcagct tgcggatgac
      241 gacgttcagg tcgcgctgat tccccgttgg accgtaataa ttaaagccgt agctgagctg
      301 ggcgtagcca ccgatcatct gtgtcggctt gacgtgaatc cttgtcgggc tgttatgggt
      361 gcctccgcgg ttattcgtca gctttgtgcc gggcacgttg atgtggcggt cctgggcatg
      421 gtgcataaac gccattcctt taggaatccg atgagacaaa acggctctcg cgacaacaac
      481 accgtttcgg ttaaagcatt caatccaatc gttgtctttg atatccgtgt cctctgcatc
      541 atctttattc atccacacgg ttggcccacc gcggaacagc gtcagcattg gcagagaatc
      601 aaaatacatg ctgtggacag accatttatt atgcggcgtc aaataattga ggacgatttc
      661 ttttccctct tgatcaggcc gcttgctcag aaacgggcga tgctggagga tcggtttgaa
      721 tgtcgccatc gtttcaccga attccatcat cagttcatga tcgacataat aggattgtct
      781 gcctgtcagc gtccgccacg ggattaattt ttcaacattc gtcgtaaacg gcgaatacct
      841 gcgccctcct ttttcagagc cggaaaacgc tggagacgtg atcaccgttt tcggctgggc
      901 tgtaatttgt tcgaacgtaa agcactcttc ctcgcgttct tccgccaggt ctttcagctt
      961 caggttcgtg atgttttcaa gtgattccca tgctttgacg gcgacctttc cattcgaagt
     1021 ggatgatagg gttaaaaccg cttctgccgc ctgctttgct tcacttatat ttggacatcc
     1081 ctttgccacg ctgtctgagg tgatttctcc cagtctcttt ttgagtgatt catattcatc
     1141 ggctattgac cagctcatcc cttttgttcc gctcggcttt aaagcagcgt taggaccgag
     1201 tgcggtcatt ttatgaaaaa tgtgtttgta atcccgttca acgacttgga tgttcggcat
     1261 cgtttttccc ggaatggctt cacattcgcc cttgctccag tcattgattt tgccgaatgg
     1321 ctgggccaat tcctgcatgg tgtcgtggag gagcggcgtc gcaaccactt ctttcaccgg
     1381 ctccatattg acttcttctg ccagatcgga aacggctttt gacagcgcct tgaaaatatc
     1441 ccagtctgac ttcgattccc acggagctga gatcgccgga gcaaatggat gaatgaacgg
     1501 atgcatatct gtgctgctga gatcgtgttt ttcataccat gtcgccgccg gcagcacgat
     1561 atcggaatac agcgccgtac ccgccattcg aaaatcaaga ttgattaata agtcgagctt
     1621 tccttccggc gcctgctccc gccatttgat ttcttctggg cggatgctgt cgctgtcgtc
     1681 attcattaaa ccgttcgttg tccccagcaa atgcttgaga aaatattcat gcccttttcc
     1741 tgagcttgag atcagatttg cccgccatac aaagagattc cttgggaaat tcacttcatt
     1801 gtcaggatct tcaatcgcga atttcagttt tttctcttgg agctgtgagg ccacgtacgc
     1861 acctacgtct tcaggtgttg ctgcccctgc tttttcagct tctttataca gatcgatgcc
     1921 attttgattg aaagtcgggt aagacggaag ccaccctagc cgcgccgcca gcacattgta
     1981 atcagcgtgg tgcttgtagc gggatgacgc agcaatcggt gatgccaaat cactgatcgg
     2041 ctggtcctca taacgccact gatctgtcgc aaagtagaaa aatgaagtgc cgttttgcag
     2101 cttgggcacg ccctcccagt cctttgcagt tgcaatcgtc tgccatcctt cagcaggtcg
     2161 gagcttttcc tgcccgacgt aatgggccca gcctccgcca tttacgcctt gggcgcctac
     2221 aagcaaaaca agatttaaca ctgctcggta gatcgtgtcg gagttgaacc agtggttaat
     2281 gccggctcct acgataatca tagaccggcc gtctgtatcg atcgcatttt gagcaaactc
     2341 tctggcaatc ttaacgacag cttctttttt gattcctgtc atttgttcct gccaggcagg
     2401 cgtaaacggc tcaggatcat cataggagac agcttgttgt tcgccgatgc cccgatttac
     2461 gccgtagtta gccagtatca agtcaaacac ggtcgtgacg tacgtctctt caccgttcag
     2521 gttcattttt ttaataggaa gatcccgctc gagcactttg tttccgtcat ttgaaaaata
     2581 cgggatgcgc accgtgccga tttcatcctc tattccgagc acagagagac ggggttcaat
     2641 cggttccccg gtttcttcat caatcatgtg caggttccat ttctgctgcc cgtcccagcg
     2701 cgagcccatt gtcccttggg gtatggcaaa tgaacttgtc tgttcatccc aaaccgcagg
     2761 cttccactga tcatgctttg tcttccgccc gatgtccttc gcatgcagaa accgtcccgc
     2821 tgtgtatacg ccattttctt ttgacagagt gacgagaaat ggaaaatcag tgtattgctt
     2881 cgcgtactca ataaaacgtt cagtttcttg gttcacgtaa aattcctgca gaataacgtg
     2941 acccatcgcc atcgcaagcg ccccgtcagt cccttggcga atactcagcc agtcatccgc
     3001 gaactttgag gattccgcaa aatctggact gatcgaaatg accttagcgc ctttatagcg
     3061 ggcctccgcc aaaaaatgcg cgtcaggcgt tctcgttaac ggaacgttgg agccccatgt
     3121 gataatatag ccggaattgt accaatcact gctttccgga acgtccgtct ggtcacccca
     3181 aatttgcggg gatgctggag gaagatccgc ataccagtca taaaaactga gcatagggcc
     3241 tccgattaac gacataaacc gggagcctga tgcgtggctg atcatggaca tggccggaat
     3301 cggagaaaaa ccgacgtttc ggtcaggccc gtatttcatc actgtataca gcagagaggc
     3361 tgaaatcagc ttcagcacct ccggccattc agcgcgcaca aaaccgcctt tccctctcgc
     3421 ctgtttatag gacttcgctt tttcagggtt ttcgacgatc gatttccagg cttccaatgg
     3481 attttgatgc gtctgcaatg cctcccgcca caaattgatc agcacaccgc gcacgtatgg
     3541 atatttcaca cggagcgggc tgtagatata ccatgaaaaa ctggcccccg cgggcagcct
     3601 ctcggttcaa aatcaggcat atccgggcct gttgatggat aattcaaatt ttgcccttcc
     3661 cacgtgacaa ttccgttttt cacataaata ttccagctgc aagaccctgt acagttgacg
     3721 ccgtgggtgg agcgaacgac tttgtcgtac tgccatctgt ttctgtatac attctcccaa
     3781 tcgcgatcct cgcgggtagt ttggctatgt ttatttgaat ggtgttcgat aggagagaaa
     3841 taattcaatc tcctaaacaa cggactcatt ttctttttct tcatgagagt tcactccttc
     3901 cgagtcaggt gatgctaagt tcactataaa cagagacagc gtgttttctt gtgaactatg
     3961 tcacacactc tgcttttttc acaaaatgtt cacacaaagg agaaggaagg ctgagttcag
     4021 gcaggacgct tgggtcatta gctgcctttc attcaaagat caaaaaaaac cggctctatt
     4081 taagaaccgg gctcggcgtt ttcatcctgt gatgtatgca gataccgcaa aaataattga
     4141 taggaacaaa aaacattttg ctgaagcata gccaaaaagt tcatttgcag ctgcggatga
     4201 taagacatca ttttcttaaa tatgtaatat gggatgttga gaatcagaat gtctgaagtg
     4261 gcattgactg agataaaggg cgataaataa agcccgcctt tttcatcaat cggaaacaca
     4321 tcgccttttt cccacagcgc aacggttttc gacccttcag ggagccttgt gtccataaaa
     4381 cggacactgc cttttaatac aatataaaca gattgagaat gaagaaaaga tggagactga
     4441 tcacatgaac cgcggataaa cgtgccgttt ttcagcaagg tttcgacaat ggatagaggc
     4501 acttcattaa acataggaag ttgtttcaga aataataaat agtcacactg attcatagga
     4561 aaacctcctg tgctaagcta aggatagctt tagtgtagct cgactgagcc tgtacagcag
     4621 tgatgtattt cacagcctgt atgatgaatg tcacttatca ggagggtgaa tgcatttata
     4681 atgaaagaaa aaaggaggat ttcgatgaag gcgctgattc cgaagcagca cggggcgtgg
     4741 gcgatgctgc tgatcccatt tttactcggc atggtcaagg gaggccccgt tatttggcat
     4801 attccgctct tcctaggctg gcttttccta tacttagcgg tttatcccgt tacgcttgcc
     4861 ttaaaaaaga accaaagcaa accttatcaa aagtggatgt gttattacgg ttttcccgcc
     4921 tgctgctttt tgatgatctc ggtctttcat aagccgcctc tcatctgggt gggcgtttct
     4981 ttactgccgc tgtttctcat acatatgtat tttgcccgca gaaaaaaaga acgagcccta
     5041 ttgaatgatg ttgcaggtgt cttgttcttt tgttcgggcg ggtttgcgag ctgctggctg
     5101 gggatgggaa ccctcgacgg ctgggcttgg tttattttct tgcagtctgc tttatttttt
     5161 atcgggagtt ccttttatgt gaaatcggtg attcgtgaaa gaaaaaacag gacatttgca
     5221 tactggtcat ggggatatca cctgctgctc ccctttttat ccgctctttt cggagcagga
     5281 tgggcgtttc tcgcttttat cccgagcagc ttgcgggcat ggttttttca tggaagggat
     5341 tggcccgtaa aaacgattgg cattctggaa atcgtgaatg cctgtttctt tcttgccgtc
     5401 atgtgcctgt ttatcacaag gtaaaaaaac aaggacaccg ctgtccttgt tttttcagtc
     5461 aatattgcaa atctccagcg ggcaattttc acactcaatc tcacatcgta aatagtcccg
     5521 cttgtgcaaa ataatttttc cggattcgtc tatcgaaata accccttttt tgcggagatc
     5581 tcccagcata cggttgatgc tttcccgtgc agccgcacaa aactttgcca aatcctgatt
     5641 tgtcaggaca atgttaatca gaatgccgtc gcttcgctcc actccgtagc tgtttgataa
     5701 gcggataagg gtagaataga gcgccccctt tttgccatga agaagcagat ccctgatttt
     5761 ggactgaatc ttccggaggt gcgtgctcat ccatttcatg aactcaaatg tcaaagcgcc
     5821 gttttggatt aattcttttt ccagcttatt tttattaatg acgagcacct cgccatcctc
     5881 tagtactttt gcactgagca tataccttgg ttcttcagtg aaaagtgtta attctccgac
     5941 gatatcatgc ttttggcaga ttctaagcgt caggtctttt ccgtcagatg tcagcttgcc
     6001 gatttcaatg agtcctgatt gaatcagata aagctcttct gcatccattc cttcccgaaa
     6061 caaatacgtg tgtttttcca tttttctttt cgtgctgatc gattccagca attcatacag
     6121 atcgctggat atatgatcac tatcagatgg tcgaacagag agaaaattca tgagctcacc
     6181 tcgaagaaag tcacgttgtg tgtttattgt aacgtgaatt gatttgtacc catcgagaaa
     6241 aaactaacaa tcttgtgaat gccccagtgt tagttgatgc tctggctgtt tctctccgtg
     6301 tgtgttttca ttctttcctg ccaatacatc catatgacaa ggacaaaact ggctaacgcc
     6361 acctctgaaa gcgccataaa cccgatcgcg tactggcctg ttgcctgaaa tacactcgcc
     6421 aatatgagcg gaggaaaaaa gccgcctaaa ccgcccatgg cagacacaat cccattggca
     6481 atccccgctt gcttcgaaaa atagaaagga accagtttaa aaacagtccc atttcctacg
     6541 cctgagcaga cggccacggt taatgatcca aacgtataaa ggccgattgt cggcgagaac
     6601 gataggataa tgcctgataa tgtaagcccg gcaaaaacaa acatcaagat gcggagcggg
     6661 ctcattttat cagccaggaa tcctcccgca ggcctgagca gcgtagaaac cgcaataaag
     6721 ccagccgtcc gcaagccggc atctgcagga ttcagcccaa aatgctccac cagaaagttc
     6781 ggcagataga tagtgaaggc gacaaaggca ccgaacgtaa taaaataaaa caggctcaga
     6841 aaccatagca catgatttcg gtaaacagct ttgatttgag tcttaacaga aactttgacc
     6901 ttcttctcat gcctgtcgcc aaacaatacg tgcagtaagg caaagacaga cagcaaaatc
     6961 agatacattt gcacggttga tttccacccg acggcttgag cgataaccgg cgctgcaaat
     7021 gtcgtaacgg ctgtcccgat atttcctgca ccgtaaatcc cattgacgac accgtgcttt
     7081 tctttcggat aatatttcgg gagggaggtc accccaatgg aaaacaccgc tcccccgatc
     7141 cctaagaaaa agccgcctgc gattaaatca aacagagaat ccgcgatact gatccaaaat
     7201 acaggaaata aaagcaggat gaaactgacc ataaacatga gccgcgcgcc aaacctgttc
     7261 gttaaatacc ctaaaggaat gcggagaagc gacccgagga tcacaggaat cgccgtcacc
     7321 aaagaaatct cacccttgct taaatgaata tctaatgtga tttgggaaat gagtgatgaa
     7381 atcagcaccc aaaccataaa ccctgccacc aagcttaatg actgtaacga taattgaatg
     7441 tgttgacggt tgatcatttg gcttgcccct ttcaatgatt caataatcag tcttatcata
     7501 caaaaactcg gcaaacagga ttgtgaatta catcacacgt ttttctcata aaaaaaggac
     7561 aaagcccgaa gactttgtcc ttttgatcgt gattacattt tttccggagc cgatacgccg
     7621 atcagctgaa gcgcattgtt cagcgtaatt tgcgttgcct tcattaaagc caggcgcgcg
     7681 cggctcttct cttcattttc agggtcgatg actttctctg cgttgtagaa gctgtgcaga
     7741 gcagaagcca gatcataaat atagtttgtg acacggtgcg gaattcgttt ttccgctgct
     7801 tccgccactg cctctgggaa gccgccgatc gttttcagca gatcgtattc tttttctgat
     7861 tgaatatggc tgaaatcaag atctgccgcc ggtttaagtc cctgctcttc cccttggcga
     7921 agcatgctgc aaatacgggc atgcgcgtat tgtgcataat acacagggtt ttcgttagat
     7981 gttgatacag caagatctaa gtcaaaatcc atatgggtgt ccgcacttcg catcgcaaag
     8041 aagtaacgaa cggcatccaa gccgacttct tctatcaggt cacgcatcgt tacggcttta
     8101 ccggtccgtt tgctcatttt cattttctcg ccgtttttgt aaaggtgaac gagctgaatg
     8161 atttctactt caagcgttcc tttttcatag cccagcgctt caattgccgc tttcatacgc
     8221 gggatgtagc cgtggtgatc ggcgccccaa acgttgatca gcttatcaaa gccgcggtca
     8281 agcttgtcct tatgatacgc gatatcagga agcaggtacg tgtacgtgcc gtccttcttg
     8341 atcaatacgc ggtctttatc atcgccgaac gtcgtggaac ggaaccaagt cgcgccgtct
     8401 tcttcataga catggccttt ttcgcggagc gcttcaagcg ccgtgtcgat ttttccattt
     8461 tggtacagtg aagtttcgga ataccacaca tcaaacggca cacggaagtt ttccaagtcc
     8521 ttgcgaagct tgtccagctc gtatttcagg ccgtattcac ggaaaaacgc gaggcgttca
     8581 ctttcctctt cgttaacgaa acggtcaccg tattcctcag cgagacgctt tccgatcgca
     8641 atgatatcct cgccgcggta gccatcctcc ggcatcggtt tttccaatcc gagcgcttca
     8701 aagtaacgga cttcaacaga aagcgccaga ttgttgattt ggtttcccgc atcgttaatg
     8761 tagtattcgc ggcttacatc gtaacccgct tttgaaagca cgttgcacaa ggaatcgccg
     8821 acagccgccc ctcgcgcatg cccgaggtga aggtctcccg tcggattcgc tgatacgaat
     8881 tctacctgaa ctcgttcacc gtttccgatg ttcgtttccc cgtatgcttc ccctgcttcc
     8941 agtacagacg gaatcagctt tgttaaatat tgattgttca tatagaaatt gataaaaccc
     9001 gggccggcga tatccagttt ttcaatcgaa gcctttcctt tatcaaaatg ggcgacaatc
     9061 tcttcagcga tttggcgcgg cgcttttttt gccactcttg ccagctgcat cgccatattc
     9121 gttgagtagt cgccgtgtgt tttatctttc ggtgtttcta aaacaacatt gggaatctgg
     9181 ctttcttcag ccagtcccgc tttcagaacg gccgctttaa tttcttcttt cagcacgtcc
     9241 ttcatttgtt ccgcaatgtt catgcgtgag ttcctccctc atacgtgatc gtcatattat
     9301 gtaaatgctc ctgctcgtct ccgacatgca tgtcatatgc gatgctgata cggccttttt
     9361 cttcatcgag atcagattga atcgattttg tgcttgtttt cagctcaagc tcaccaaatg
     9421 acattttata tttagcaatt gtggaagctc ccgttacgaa acgctgattc attttgacag
     9481 cgcctgacct catgaccagg acttcgcctt cgcttacttt cacaatcgtt ttgactttgc
     9541 ctaagtcgtg ttcttcataa taagatagat acactttatt ttgttttaca tagtaaaatc
     9601 cggtggtgcg gaattcgatg acttcttggt ttccgtcatc ctcgatcaca gacttcacat
     9661 ggagtgttat cggtgtctct tgcttcattc tgacacgtcc ttttcatcat tccactttga
     9721 cttgaatagt ataatcattc ggtttgtaaa cttcaactgc ttctatctta ccatcattgc
     9781 tcatcagatt tgaagataaa cctcataaaa agcatttcct tatatagaag agaaaatcat
     9841 atcactaatt acctttagga aatgttacat ttttccgaaa tctatcattt ccttttcaca
     9901 tttttttcaa aatatatgta ttgaattagt aatttgatag ttttaagata aaagtacaac
     9961 atagatctgc tagaaaaaca aaaaaaggga ggattcaatt atgaaaaaag ctgtcattgt
    10021 agaaaacaaa ggttgtgcaa catgctcgat cggagccgct tgtctagtgg acggtcctat
    10081 ccctgatttt gaaattgccg gtgcaacagg tctattcggt ctatgggggt aaggatctcc
    10141 caaaagggca tagtcattct actatgccct ttttaagtaa attacaattt ttaactaaaa
    10201 tctacctctt ggatatacat acacaaccgt ttttcatttg aatcatatgt ataggggatg
    10261 gtattttgtt tatagagcag atgtttccat ttattaatga aagtgtaagg gttcaccagc
    10321 ttcctgaggg tggcgtgtta gaaatcgact acttgcgcga taatgtctcc atttctgact
    10381 ttgagtattt ggatctcaac aaaacggctt acgagctttg catgcgcatg gatggccaaa
    10441 aaacagctga gcagatttta gctgagcaat gtgcagtgta tgatgaatca ccggaagacc
    10501 ataaagattg gtattacgac atgctcaaca tgctccagaa caagcaggtt attcagcttg
    10561 gaaaccgggc cagccgccat acaatcacca cgagcggaag caatgaattt ccgatgcccc
    10621 tgcacgccac ctttgaactg acgcaccgct gtaatttgaa atgcgcccac tgttatttgg
    10681 aaagctcacc tgaagcgctc ggcaccgtgt cgattgagca attcaaaaaa acggctgata
    10741 tgctgtttga taacggtgta ttgacatgcg aaatcacagg cggagaaatt tttgtccatc
    10801 caaacgccaa tgagattctt gactatgtgt gtaaaaagtt caaaaaagtc gctgtcttaa
    10861 caaacggaac actcatgcga aaagagagtt tggagctttt gaaggcttac aagcaaaaaa
    10921 tcatcgtcgg catttctctt gatagtgtca attccgaggt ccatgactcc tttagaggga
    10981 gaaaaggctc ttttgcccaa acttgtaaaa cgataaaatt gttgagtgac cacggtatat
    11041 ttgtcagagt cgccatgtct gtcttcgaaa aaaacatgtg ggaaatccac gatatggccc
    11101 aaaaggttcg ggatctcggg gcgaaggcgt tctcttacaa ttgggttgac gatttcggaa
    11161 gaggcaggga tattgtccat ccaacgaaag acgccgagca gcaccgcaag tttatggaat
    11221 acgagcaaaa tgtgattgat gagtttaaag atctgattcc gattattcct tatgagagaa
    11281 aacgcgcggc aaattgcggc gctggctgga agtccattgt gatcagcccg ttcggcgaag
    11341 tacgtccttg cgccctcttt ccaaaggaat tttcattggg aaatattttt catgattcct
    11401 atgaaagcat ctttaactcc cctctcgtcc ataaactgtg gcaagcgcag gcgccgcgct
    11461 tcagtgaaca ttgcatgaaa gacaaatgcc cgttcagcgg ctattgcgga ggctgttact
    11521 taaaagggct gaactctaac aaatatcacc gaaaaaacat ttgctcttgg gcgaaaaatg
    11581 aacaattaga agacgtggtc cagcttattt aggagggaaa cgatttgtca ccagcacaaa
    11641 gaagaatttt actgtatatc ctttcattta tctttgtcat cggcgcagtc gtctattttg
    11701 tcaaaagcga ttatctgttt acgctgattt tcattgccat tgccattctg ttcgggatgc
    11761 gcgcgcggaa ggctgactcg cgatgagcat tttggatata cacgatgtat ccgtttggta
    11821 tgaacgggac aacgtcatct tagaacaagt agatttacat ttagaaaaag gcgccgttta
    11881 cgggttgctt ggggtaaacg gcgccggaaa aacgacactg attaatacgc tgacaggcgt
    11941 gaaccgcaat ttcagcgggc gctttacact gtgcggaatt gaagcggagg ccggcatgcc
    12001 gcagaaaaca tcagatcagc tgaagactca ccgttacttc gccgccgatt atccgctgct
    12061 atttacagaa attacggcga aggactatgt gtctttcgtc cattcgcttt atcaaaagga
    12121 tttttcagag cagcagtttg ccagtttggc cgaggccttt catttttcga aatacatcaa
    12181 caggagaatt tcggagctgt ccttggggaa caggcaaaag gttgtattga tgacaggctt
    12241 attgctgcgc gctcccctat ttattttgga tgagccgctc gtcggtttgg atgtggaatc
    12301 gatagaggtc ttttatcaga aaatgcgcga gtactgtgaa gcaggcggga ccattttgtt
    12361 ttcttctcat ctgctcgatg tcgtgcaaag attttgtgat tacgcggcta ttcttgacaa
    12421 caaacagatc caaaaggtca ttccgattgg agaggagacc gatctgcggc gggaattttt
    12481 cgaggtgatc ggccatgaat aacataatcc ccatcatgtc tttgctgttc aaacagcttt
    12541 acagccggca agggaaaaag gacgccatcc gcattgccgc aggccttgtc attctggccg
    12601 tgtttgaaat cgggctgatt cgccaggccg gcattgatga atcggtgttg cgcaaaacgt
    12661 atatcatact cgcgcttctc ttaatgaacg catatatggt gtttctttct gtgacatctc
    12721 aatggaagga atcttatatg aaactgagct gcctgctgcc gatttcttca cggagctttt
    12781 ggctcgccca gagtgtcgtt ttgtttgtcg atacctgttt gagaagaact ttattctttt
    12841 ttattttacc gctgttctta tttggaaacg gaacgctgtc aggggcgcaa acattgtttt
    12901 ggctcggcag gttttcgttt tttaccgttt actccattat tttcggagtt gtgctaagca
    12961 accacttcgt caaaaagaag aacttgatgt ttctgctgca tgcggcgata ttcgcctgtg
    13021 tatgtatcag cgccgctttg atgccggccg ccacgcttcc gctttgcgcg gtgcatatgc
    13081 tgtgggcggt gatcattgac tttcctgtct ttctgcaggc gcctccgcag cagagcaaga
    13141 tgcattcatt tatgcggcga tctgaatttt cgttttacaa aagagaatgg aaccgattta
    13201 tctcttctaa agcgatgctg ttaaattacg cggtaatggc ggcgttcagc ggcttctttt
    13261 cgttccagat gatgaatacc ggcatcttca atcagcaagt ggtttatatc gtgatttccg
    13321 cgcttttgct catctgctcg ccgatcgccc ttttgtattc gattgaaaaa aatgaccgga
    13381 tgctgcttat cacgcttccg atcaagcgga aaacgatgtt ttgggcgaaa tatcgctttt
    13441 attcaggcct attggcaggc ggatttctcc ttgtcgtgat gattgtgggt ttcatcagcg
    13501 gccgtccgat ttcagttctc acttttttgc agtgcattga gttgctgctg gcgggagctt
    13561 ttatcaggtt aactgcggat gaaaaaaggc cctccttcag ctggcagacg gagcagcagc
    13621 tatggagcgg tttctcaaaa tatcggtctt atctgttttg tcttccccta ttcttagcca
    13681 cattagccgg caccgctgta tccttggcgg tcattccgat agccggtctg gtcatagtct
    13741 attacctgca aaaacaggat ggtggtttct ttgatacaag caaaagagaa cggcttggaa
    13801 gttaacctgc tgaagactca tcaattttca actatttcaa tcgccgcgag ctttctgaaa
    13861 ccgatcgaaa gcgcggcgga acctgaggaa gaaacgattt atttttacgg cgccgccgca
    13921 tacctgaagg agcaaattat tgacgctttc ggttgtgctg ccggcagccg tttcatgtac
    13981 tcagcgaatc tcttttttga tcagcagctg aaaacctgcg ggacccgttt gattcaccca
    14041 ttatataacg ggaatcttca tgttgacgcc ctgctgaaaa cttttgcaga cttgtctttc
    14101 ccttcttctc tttcattcga agcagttgaa aaggccagga atgagctgct gctgagaatc
    14161 gaaaagaaat tcactgatcc tttctcctac tcggcggcgc gcttggctga ggaggtcttc
    14221 ggaaacccga tgtacggcac aggcatgttt ggccggaaag acaggataaa ggcgattcat
    14281 cctaaacggt ttctcgacgc aacggacttt atcgttgatt tagtgtccca gcaaaaacag
    14341 ctgaacatat tgggacaagt acaagcatgt gatgttcggg gacatgcccc gcaaacgtcc
    14401 gctgtaacgt ccgaaagaat acccgtaaac cggcatgttt ttgaaacaga gacacgcagc
    14461 gctgcaggtc cttccgtctt gacactcgga tttgactgcg gagagatgaa agatgccagc
    14521 gattatatca aaatacagct aatagacgga ttactgggaa agtacggcca ttccgcttta
    14581 ttcaagcact tcagagagaa ggatctggca gtctatcacg ttatcacccg ttacgatgtc
    14641 atgaacaatt tgctgcttgt ttcaatatgt acagatcagc ttcatgagat agacattccc
    14701 ccgcgcgttt tggaagctgt ctcagctttt catacagatg agcgggaact agaacaggca
    14761 aagcagtttt tacgcaatga attgctgctg caattcgatt ctcccgaagg tctattggcc
    14821 tatatgggga tcctgcgccg cttctcctgc acgaaagaag ccttgctgga tggcatctca
    14881 gcggttacat gccgtgatgt attgcaattc atagcgacca tcaattatat cggagctcat
    14941 gtagtaaggg gatgaagaga tggaaaagaa agcctttttt caacaactgg atgaacgaac
    15001 cgatatcaga tacacagaca gcggactaaa aatattcaga ttgaaattcc cccgcgccca
    15061 cctgcggctg tgcaatgtaa aaatcgattt tggaagccgg gatgtatgta tacgggcaga
    15121 atccggtgat acactgcttc cgtatggcac agcgcatttt ttagagcatc ttctcttctg
    15181 gcataacggc cgcaatctgt acagtgattt ttttgcgcat ggcgcgcttt taaacgcatt
    15241 cactacctac accgatacca atttcatgtt tacctcatta ccggatcggc tcagacaaac
    15301 gatccccatc ctgcttgatg ctttatggaa ccactcattt gacaagaaga ttgtcgctca
    15361 ggaaaaagct gtgattacaa gcgaaattca aacagcacac cttaaccatc agctctcata
    15421 tcattatcag ctgatcagca tgctttctcc ctcctcacca gctgccgttt tccccgcagg
    15481 cagaatcgaa gatattgagg cgctggacat cagtgattta caaaaagcct ataaggctgc
    15541 ctaccaagcc catcggatga cgctgttttt gattgggggc tcagaaaata cagaaacgct
    15601 tttgcctcct cacctccagc tggaaaaacg tccggattat catgctgaaa gaaaaatcat
    15661 cccggcatgc cctccagccc tctcacaaaa aatggtgctg ggtgatgagg agcggatgga
    15721 agatacatgg accggattac agatcggcgc acttcccggg caaaacgatc tgttggcgat
    15781 aaagctttat tgggatatcg cggctcgtat tctatttcaa ttagattcac cgttttttca
    15841 agagattcag caaacgtacc gtctggaaat cgatcgcttg tcagccgaga cttatatata
    15901 tgaggatggc ggtttcttga tccttcacag tcaagggacc cattcttcag cttatatcga
    15961 tgtggcttca tactatgtca cacagaagaa agaacaggtt gccgcctggc ttcaatacgg
    16021 caaggactct ttgacagacg cgatcattta tgacagcgat tatgtgcgta aatgcttcga
    16081 gtgggcagcc gagtgtgaca ggtgcgattg ctcgtttctt gacatgtacc acatcattca
    16141 agatatggat gcgcaggttt tcttgtctct cattgatgca atggcatctt ctaacaaagc
    16201 gatcattcac gtttctcaga aagaggcgat cagacaatga aaaaaagcac tgtctttacc
    16261 cttttattgc tgcttatagg tatggcggct tattccttcg gatgggttca ggccgttgcc
    16321 gaagccgccg cccaatatgt acagatgatc aacaatgatg ctgttcggct cggactgctg
    16381 gcttgtaccg ctgccctcct gatgctgcct gcttttctat atcttcatta tgtcacccaa
    16441 tccgtgaaaa acatgacagc agcttttcag aaactcacac agtctcatca aagctgctgt
    16501 gactttcagc aacacaactt gtgcagccga tatgcagaag acgtcaaatc gctgcgtgac
    16561 agctataaaa acgtccgcca aacatacgtg atggctgccg tgttgtgcca agtcatcata
    16621 ttcggctgca tgttcgaaat cgttaaagcc gtccctttcc gccttcacac gccccctgcc
    16681 ctttcaatgg gacttgcgat gctactgatt ctgtatttat tgttttgcat gcgaacttat
    16741 ttgcggcagc ttttccggca cggcagcctg ttcagaaaag tgtttgcggg agcgctggca
    16801 gcagccggga tttggtggat actcagtttc tctataagtg aactgctgtt tctgattatc
    16861 ctggctacca ttcagcaaat cggatcattt atttataaac gattctctta tcgcagcacc
    16921 gcttctcttg atctataaaa tagctacatc gcaatcgcag acggacccgc gccaaccgga
    16981 atcaccgtca cggctgtata atcacttgtg cggtacacgg tcacagcatt gtcgttgggc
    17041 tgtgccgcat aaatatactg tttgtccggc gttacggcga ggtcaaaagc gccggggaga
    17101 gacacgtttg caatgatcct ctgtctggcc gtattaacta catataagtt attaataaga
    17161 aacggttcac tatatggctc tagaaaataa gctctagtgc tatcgagaga aaatacaatc
    17221 gtcctcagcg tttcaaataa acggctgaag tcccctcccc tgcttaatgg agacaaacta
    17281 atctccgtta cacctttcgg ccacagctca ccattcaaca cgtacgcaaa atttccagcg
    17341 taaggagttg caattaaact gggaaattca aatgtatcta tgatactttc taccaactgc
    17401 ccagtattta tatcatattt atcaaccgac caactgcttc cattagcggt atagacatac
    17461 tgtccattcg gatcaagagc aaagtctaaa gcgccgggta tcggaatgac atcaatgacc
    17521 gattgagagg ccgtgttaat cacatatata gatccggcgg ccatcacgta tgcgaactca
    17581 tcttttggat caaattcgat ctttctcggc cctcctccaa cagtaatggt atttatgatg
    17641 gttaatgttt tattatcaat cactgagaca aggttggtat ttccatggag gacatacgtg
    17701 aatgctttat cgaaagtaac gcctagatta gttggcacgt cagaaaaagg gattgttttt
    17761 acaacagtgt ttaaatctgc atcaataacc gaaaccgtgc tgtctccagt attggcagta
    17821 aacacatacg attgagggtc tggtgatggc ggtaaaacaa gtgtcccggt caccgtaagc
    17881 ggactgccgt agaaaggcgg tacaatgagc agatcttcca ctgttatttg actgaaatca
    17941 ggacagcggc cagactgtgc tgcataataa acaacttgat caatctcttc ggtatgaatc
    18001 acagaaaccg ccccattgcc ttgtccatat tgatttcgca caggcgacac actgacaaga
    18061 agcgtaatgg tcccttgtac tctcacagca tatcgaacac cgatatcttc tggttccggc
    18121 ccagtctgga ttaagcaagg ctcactgata caggacacat tgtctgtact ccatgtaaca
    18181 gccgctgacg cttcggccga atcaaccttg aagccctcag ggatatctat cggcacttga
    18241 aacggcgctt ctcggctaat ttcctcatca caaaaacaga aacaattttc ctgtaaagca
    18301 gaaagatcat tctttttcat gatttcacgt ccttttagaa atgcacaaca tgcagcggtt
    18361 aaatcgtaat ggcacccggt gaaaccccaa gagatatcac agtttcctca gaataatcat
    18421 ctgtgttgta aacaatgatg ctctgctcta taaaacgagt tgcatacaga aaatcgccat
    18481 tcggggtaaa cgcatagtct gttgctgatt gcggaagatt tccaattaca cctgctccat
    18541 tcggactgac agaatataaa ttgccagtga agctgtcatg taaatacacc tctgatccac
    18601 tcgtaaacat tacatatagc ccgtcaggct ccagctcttg ggtatccctg atcgtaaacg
    18661 tatttaaatc aataaccgtc aaataattga ataagaattc ttgttctaat acatacgcat
    18721 accgctccgt agaatctgtt tctatggatg atacgataag ctctcgttca atcgttccta
    18781 agacttcacc ggtagataag tccacttttt gcactaaccc aaaattaaga acataggcga
    18841 acaacccatt ggggtcaatt gcaatatcaa aaccttctac aggaatagac ctctcaacag
    18901 tcaacgtatc aattccaatc acataaatgg cagtaccggt gaaaacataa gcaaactcat
    18961 gattagggat aaatctaatc aatcgaggcg gctgatccag caatatagtt gctgtcactg
    19021 ttaatgtgtc ataatcgatg acagaaatca cattattgtt gggatgtaag acaaacacag
    19081 cgcttttatc tggcgtaatt tcaatacctg ccggattgta cggaagagca atcgttgtca
    19141 caacagaatg agtgtttgta tcaatcacag aaactgattg atcatttgga ttcgctgtaa
    19201 acgcataaac gggttccggc tccggtacaa gcacaatcgt ccccgtcacc gataaaggac
    19261 tgccgtaaaa cggcggaaca acaacaaggt tctcaatcgt gatgtcactg atatccgggc
    19321 aatcatccgg ttcatcggaa taatagacga cttgatcgat ttctgcattg tgaatgacgg
    19381 aaacagcccc gtccccttgt ccatattgat ttcgcacagg tgagacactg acgagtagcg
    19441 taacggttcc ctgcaggcgc actgcaaatt gaacaccgat ctcatcaggc tctggccccg
    19501 tttgaattaa gcaacggtca ctgacacaag aaaggctgtc tgcattccac gtcacgtttg
    19561 caacagcttc agccggatca acgacaaatc cttcaggtaa ttcaatcggc gcttgaaaca
    19621 tggcttctcg gcttgcttct ccctcacaaa aacataagca ctcttcttgt tctgctcctg
    19681 ctttttcttt aaaggaaagc ttgttttttc tcattccttc acttcctttt cagacataca
    19741 ctgctcacgc agatataaca gaatatggaa gtgtaacgtg tttgcttgta caaattgctg
    19801 agggtaaacg cttctttttg aaaatatatc tccaaacatg cggtgtaacg aaagaaaaaa
    19861 ttgcggtttt tttgcgcttc tcacaagaat gttgatgata aaatatgaca tatatagaat
    19921 tatgaaggga gggatttgca aacgtgacag gtgtcatatc ttcttcttcc atcggagaaa
    19981 agattaacga atggtatatg tacatacgcc gatttagcat acccgatgca gaatatttgc
    20041 gacgagaaat caagcaagag ctggatcaaa tggaagaaga tcaagacctt catttgtact
    20101 attcactgat ggagtttcgg cacaacctga tgcttgagta ccttgaaccg ttagaaaaaa
    20161 tgagaattga ggaacagccg agactgtctg atctgctgct tgagattgat aaaaaacagg
    20221 ctcgtttaac tggtctgctt gagtactatt ttaatttctt cagaggcatg tatgagctgg
    20281 atcgccgtga atatgtatta gccattcaat tctttaaaaa agctgagagc aagctggttt
    20341 ttgtgaaaga taaaatcgat aaagctgaat tctttttcaa aatgtcagaa gtctattatt
    20401 atatgaaaca aacttatgtc tccatggact atgcacgtca agcattcgaa atatacagtg
    20461 aacagactac atatgatatc agaatgattc aatgccagtc cttattcgga gccaactttt
    20521 tggatttaaa acaatacgaa aaagcaattg cccattttca aaaagccttt acacttgcaa
    20581 aaacagagca gaagccccaa ttaatgggaa gaacacttta taacatagca ctctgcaagc
    20641 aaaaccaaaa cagttttgaa tcagcgatag agtatgtaaa aaaatctatt caagtatttg
    20701 aaggatctaa aatgctccct tcactgccac aagctttttt cctaattaca caaatttatt
    20761 ttaaattagg taagattgat aacgcctgtg aatatcataa aaaaggaaaa gagtattctg
    20821 cagctgcggg agataccgtg tatctaacgg agtttgaatt tttggaatct ttatacttgt
    20881 ctggaccgga tgaggaacgg atagaaaaat gttttgtttt tcttgaaagt aaaatgatgt
    20941 atgcagatat tgaggacttc gcacttgatg ttgctaaata ttatcatcaa caggaaaatt
    21001 acaaaaaagc atctcattac tttttaaagg ttgaagaagc aagacagcac attcaagggg
    21061 gggtgaattt atatgaaatg gaagtataaa ttattactcg cttgtttagc tgtgagtgct
    21121 gtatttatca cagtcgaagt atcaaattca tcaacagaac attttgatgt tgcgcaacgc
    21181 gccatgatct aaaccgccgt ccatcggcgg tttttttgtc ccctctttac ccaatctccc
    21241 aattcatgct gtgatttttt tcaataatct tgaagagagt ggaaatgcag catgtctctg
    21301 taaagtgtga gaacccactt tacacagtgg aatcgagaaa atgatgtgac ggagttcgaa
    21361 acgtcgagcg cgacagtgtt gaacagacag ctgagacgat cggcgtaagc ccgactagaa
    21421 tcgccaagac cctgtccttc agaggggaag gagatcaggc gattctgatt gtggcagccg
    21481 gcgatgccaa gattaataac aaaaagttca ggcaaacatt tggctttaaa gcaagaatgc
    21541 tctctcctaa tgaggtactg gagcagacag gccatgaaat tggaggtgtt tgcccatttg
    21601 ggttggctca tg
//
