LOCUS       NZ_CP071043            20267 bp    DNA     linear   CON 13-NOV-2023
DEFINITION  Bacillus subtilis isolate ELA2001105 chromosome.
ACCESSION   NZ_CP071043
VERSION     NZ_CP071043.1
KEYWORDS    RefSeq.
SOURCE      Bacillus subtilis
  ORGANISM  Bacillus subtilis
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
REFERENCE   1  (bases 1 to 4089676)
  AUTHORS   Tawari,N.R., Mane,S.P., Susanti,D., Volland,A. and Kumar,A.
  TITLE     Multi-omic analyses and microbiological characterizations of
            animal-origin Bacillus spp. as an alternative to antibiotic growth
            promoter to improve growth performance in broiler chicken
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 4089676)
  AUTHORS   Tawari,N.R., Mane,S.P., Susanti,D., Volland,A. and Kumar,A.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-FEB-2021) Global Computational Sciences, Elanco Animal
            Health, 3rd Cross, Murugeshpallya, Bangalore, Karnataka 560017,
            India
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 28-JAN-2020
            Assembly Method                   :: HGAP v. 3
            Genome Coverage                   :: 126.45X
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 11/13/2023 05:04:14
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,241
            CDSs (total)                      :: 4,120
            Genes (coding)                    :: 4,006
            CDSs (with protein)               :: 4,006
            Genes (RNA)                       :: 121
            rRNAs                             :: 10, 10, 10 (5S, 16S, 23S)
            complete rRNAs                    :: 10, 10, 10 (5S, 16S, 23S)
            tRNAs                             :: 86
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 79 of 114
            Pseudo Genes (incomplete)         :: 48 of 114
            Pseudo Genes (internal stop)      :: 19 of 114
            Pseudo Genes (multiple problems)  :: 26 of 114
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 08:27:42
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 3491674
            Orig. end                         :: 3511941
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP071043.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Annotated at Elanco.
FEATURES             Location/Qualifiers
     region          1..20267
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RRE-containing"
                     /region_number="10"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     cand_cluster    1..20267
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20267
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:10267](+)"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10267
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     gene            complement(364..1254)
                     /gene="ftsX"
                     /locus_tag="JS609_RS18020"
                     /old_locus_tag="JS609_03550"
     CDS             complement(364..1254)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /gene="ftsX"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391405.1"
                     /locus_tag="JS609_RS18020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JS609_03550"
                     /product="permease-like cell division protein FtsX"
                     /protein_id="WP_080530089.1"
                     /transl_table=11
                     /translation="MIKILGRHLRESFKSLGRNTWMTFASISAVTVTLILVGVFLVIML
                     NLNNMATKAEKQVEIKVLVDLTADQKAQDKLQNDIKELKGIQSVTFSSKEKELDQLVDS
                     FGDSGKSLTMKDQENPLNDAFVVKTTDPHDTPNVAKKIEKMDHVYKVTYGKEEVSRLFK
                     VVGVSRNIGIALIIGLVFTAMFLISNTIKITIFARRKEIEIMKLVGATNWFIRWPFFLE
                     GLLLGVFGSVIPIALVLSTYQYVIGWVVPKVQGSFVSLLPYNPFVFQVSLVLIAIGAVI
                     GVWGSLTSIRKFLRV"
     gene            complement(1247..1933)
                     /gene="ftsE"
                     /locus_tag="JS609_RS18025"
                     /old_locus_tag="JS609_03551"
     CDS             complement(1247..1933)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /gene="ftsE"
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391406.1"
                     /locus_tag="JS609_RS18025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JS609_03551"
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="WP_014481035.1"
                     /transl_table=11
                     /translation="MIEMKEVYKAYPNGVKALNGISVTIHPGEFVYVVGPSGAGKSTFI
                     KMIYREEKPTKGQILINHKDLATIKEKEIPFVRRKIGVVFQDFKLLPKLTVFENVAFAL
                     EVIGEQPSVIKKRVLEVLDLVQLKHKARQFPDQLSGGEQQRVSIARSIVNNPDVVIADE
                     PTGNLDPDTSWEVMKTLEEVNNRGTTVVMATHNKEIVNTMKKRVIAIEDGIIVRDESRG
                     EYGSYD"
     gene            2379..3995
                     /locus_tag="JS609_RS18030"
                     /old_locus_tag="JS609_03552"
     CDS             2379..3995
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013595.3"
                     /locus_tag="JS609_RS18030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JS609_03552"
                     /product="hypothetical protein"
                     /protein_id="WP_080529856.1"
                     /transl_table=11
                     /translation="MKLIYKDEYGPLYSEKSKNSILKEPTYFEVDSKDNLNRIVDKKGH
                     YTYQNNKLHKIKPKNIGASGSNSGYPLIMDKKGHSLEYGRDLLEVSMRNKLYIRTTEKE
                     YCYEYDTEVEPDTIQIFDDKVLLNLKLRQMVVLVSTSGKVLNSFGLDRYRGEGQKQLNV
                     PMFSVYIEDRNSILISDAINSRVIEVDENGNIIWKYGKDGLLGSDQGLLWKPTCARRLS
                     NGHTIIADSKNNRLVTIDQDKNIVNEIGQTNVSKLFLTYPRSVQMLDKYNWLVTNTHKN
                     SIFIMNQNQKKIIKPINDSYNKLNLFWPRCSIKNSDDEIIIADGKNNRIMFIDDKTLQI
                     KKVIDYYYEQGNRMTIIDPHDIKINPKTNLLLITLSGNNRVIEMTSDGELIESYDNLND
                     PHSAYYFSNGIIIANTEDNNIVIYYFSGKKEIINNFKSTNSCCDAFKRPRYALPYKNGF
                     LILDTDNQRIIFLKKENNEWIGENVPIYFPDGPIMNYLCFPRCITFNNDNELILTDTEN
                     CRILRLVIDDTLIKEEHSNEI"
     gene            3985..4929
                     /locus_tag="JS609_RS18035"
                     /old_locus_tag="JS609_03553"
     CDS             3985..4929
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF039614.2"
                     /locus_tag="JS609_RS18035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JS609_03553"
                     /product="arginine deiminase family protein"
                     /protein_id="WP_080529857.1"
                     /transl_table=11
                     /translation="MKYKVDSAHGGEGWVPRKQDHSTELGHFWNNCGVKGEFGTLSHVL
                     LRSPGLEVEQNFNPADILWTERIEPSKAREQHNNLIEVYRSQGVEVDLIDDKAAESFPN
                     ILYVRDLFTMTDQGAILSRMASEVRAGEEVIISKKLSELGIPILASLHSDMILEGPDIL
                     IVNPDLVFIGYGIRTNYKAAMYVKQILLGLGYSEVIIIQTTYGCGHLDGVVNILNSRYA
                     AIVPKRVSYELYIGLKRHGFSIIELDDMYEIDQLMSINFVQLNEETLLINKGAKNTVSQ
                     YSSCGFECLEIDISELTKGGGSIHCLTGILRRI"
     gene            4934..5896
                     /locus_tag="JS609_RS18040"
                     /old_locus_tag="JS609_03554"
     CDS             4934..5896
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF025017.3"
                     /locus_tag="JS609_RS18040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JS609_03554"
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="WP_080529858.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 2.3e-05,
                     bitscore: 22.3, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGVSIVIPIKVNSIDEIYIDFINYIIDFSSNVLTKDVEIIIANGS
                     SKNIYIFANEHLKHLKNVIHFIPHRSIRTGDNDKLNGIYSALMYTKHDNILLVDDHYRV
                     SSETLADILKYYEKYDCFKFMPKLHQYPHSALIDTCGMFIVNVLDSRKQYCGHLAFKKS
                     LYSEWGFINRDSLFDEFAMEKHLRKKGSRVGFIKDIALEAKQEIPFKKFLEQRVRYAYE
                     NIATPYRFTFFAMILPLLILLSLIDTNYGLNFAFFLTSWTFVISIVGQFIYGKQITPWY
                     TSLYSPIWFWFYPFTTWIAIYKYLTGGIMFGGNNIRRAG"
     gene            5897..6931
                     /locus_tag="JS609_RS18045"
                     /old_locus_tag="JS609_03555"
     CDS             5897..6931
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="JS609_RS18045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="JS609_03555"
                     /product="hypothetical protein"
                     /protein_id="WP_080529859.1"
                     /transl_table=11
                     /translation="MKITQKIIGPQSIVYFKKDKNREFVEKISTERGEDELVDQIHFYK
                     MLPKEIKPLFPALYDYDIKNRPFRMSMELCDFPTLKEIILYNTKQNKLKEHLYNVIQDI
                     FEKIHNLKQTQATKNYVEHLYIDRCVNRIIETKKLMKEAQWINNDFYLEGSIVSNPIQT
                     VFEIINNNKDLLIPEYLCTVHGQLGPSHLMLNIQKKNSYKLVDPKGFHEFHDPLLDIIK
                     IGRSFLYGMEWLEDDLYNIKYSFKNEYLTIEDFNLINYDEVYMKKSFKPIMDLAINNYK
                     NAALRVYALICCDLIANLPFAYLSGGEKRVVALYNLIYAASLDLSQLNDAVNKEKHIYE
                     SLSK"
     gene            6912..7403
                     /locus_tag="JS609_RS18050"
                     /old_locus_tag="JS609_03556"
     CDS             6912..7403
                     /EC_number="3.6.-.-"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012514.3"
                     /locus_tag="JS609_RS18050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JS609_03556"
                     /product="NUDIX hydrolase"
                     /protein_id="WP_080529860.1"
                     /transl_table=11
                     /translation="MKVFQNNRYNIFNYKESSIFIEDRQPHSVLTIANLKNQLVVVRQM
                     RKGINNETVELPGGQVEDNEKPMDAAKRELEEETGLIANQFIQIGNIYPLPSLINRQIT
                     YFYTENIVGYNKTIKQDEDENIHVEYHKFPKVEYNLKTQKWRDQFLAYGVYICKLKGII
                     "
     gene            7422..8099
                     /locus_tag="JS609_RS18055"
                     /old_locus_tag="JS609_03557"
     CDS             7422..8099
                     /EC_number="3.1.3.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HAD_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1115: HAD-superfamily hydrolase, subfamily IA,
                     variant"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024811.3"
                     /locus_tag="JS609_RS18055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JS609_03557"
                     /product="HAD family hydrolase"
                     /protein_id="WP_080529861.1"
                     /sec_met_domain="HAD_2 (E-value: 9e-30, bitscore: 102.0,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDVQSILFDLDNTLLNRQKTFENYLDSFISKYIFYNSPTEKKDIK
                     NKIIDMDKKGEKDKKELFSELQHRLKWRLTPSVDYLVEEYKTIFAKNSIVMDGTFEVLT
                     FCKNKNLKLGIITNGESFYQKIKLNNTNLTCFFDFILISEEFGKAKPHRSIFKFAIDKM
                     AIDPRKSIFIGDNLISDIYGASRFGFYTVWYNHSNIVKQNPITVKPNKIITSLSELLKI
                     KDW"
     gene            8116..8733
                     /gene="yqeK"
                     /locus_tag="JS609_RS18060"
                     /old_locus_tag="JS609_03558"
     CDS             8116..8733
                     /EC_number="3.6.1.41"
                     /codon_start=1
                     /gene="yqeK"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020061293.1"
                     /locus_tag="JS609_RS18060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JS609_03558"
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="WP_225722120.1"
                     /transl_table=11
                     /translation="MIISVDFLNHLHSIYNKNNDLSENVKRIFKEYKCSNIYEHSVRVA
                     HMAKKLAVRFRANEESAYIAALLHDIGGIVPNGKRIEIANILKIPLFPEEIEFPLIIHQ
                     KISKVIAEKVFLISDHSILNAIECHTTLKSNPSMLDKIVFISDKIEWDQKGSPPYINSL
                     IEALDVSIDCASNVYIKFLMENKNNLKVIHPWLSDSYNYFKK"
     gene            9195..9980
                     /locus_tag="JS609_RS18065"
                     /old_locus_tag="JS609_03559"
     CDS             9195..9980
                     /GO_function="GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF014021.3"
                     /locus_tag="JS609_RS18065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JS609_03559"
                     /product="nucleotidyltransferase domain-containing protein"
                     /protein_id="WP_080529862.1"
                     /transl_table=11
                     /translation="MSKVFDKEEILKLIPCSDKIDYIYLAGSIMEGFGNDASDIDVFVI
                     SENPDRLAYEPTNFTREVNIQVGESFIKNIVIDSIRYDFEYYRSSSFTSLIEKLNNLNF
                     NTENYIPRFTADEIDLLHRLKFAEPLLNKSAFNTILNNINFENLNNYLVITNIESYDGH
                     LEDLQGALSCSDFGTSFVLLKLLLKYSLNAYLAKYGETNPGEKWLFRKLSRYAEKHGDQ
                     HLLDKYLNLLCYPFEKDNIKHYAQKTINFTQPLIIKAQK"
     gene            10001..10267
                     /locus_tag="JS609_RS18070"
                     /old_locus_tag="JS609_03560"
     CDS             10001..10267
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Thurincin_rSAM_RRE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF017239.3"
                     /locus_tag="JS609_RS18070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JS609_03560"
                     /product="PqqD family protein"
                     /protein_id="WP_080529863.1"
                     /sec_met_domain="Thurincin_rSAM_RRE (E-value: 2.1e-08,
                     bitscore: 32.0, seeds: 5, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 3.7e-14, bitscore: 50.7,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="PqqD_RRE (E-value: 2.8e-09, bitscore:
                     34.5, seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 8.9e-12,
                     bitscore: 42.8, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIYQKNMFVRFRIIDTKPYLILNDNAFILDDVGVNIWESIDSKKN
                     IEEIINKISNVYSVESNKITKDIKNYLKDLEKNGLIEVCKEIS"
     aSDomain        10016..10237
                     /aSDomain="Thurincin_rSAM_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing rSAM protein in a thurincin
                     sactipeptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_JS609_RS18070_Thurincin_rSAM_RRE.1"
                     /evalue="1.40E-10"
                     /identifier="RREFam019.1"
                     /label="JS609_RS18070"
                     /locus_tag="JS609_RS18070"
                     /protein_end="79"
                     /protein_start="5"
                     /score="32.0"
                     /tool="antismash"
                     /translation="NMFVRFRIIDTKPYLILNDNAFILDDVGVNIWESIDSKKNIEEII
                     NKISNVYSVESNKITKDIKNYLKDLEKNG"
     aSDomain        10070..10246
                     /aSDomain="PqqD_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing protein in a pyrroloquinoline
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_JS609_RS18070_PqqD_RRE.1"
                     /evalue="1.90E-11"
                     /identifier="RREFam006.1"
                     /label="JS609_RS18070"
                     /locus_tag="JS609_RS18070"
                     /protein_end="82"
                     /protein_start="23"
                     /score="34.5"
                     /tool="antismash"
                     /translation="DNAFILDDVGVNIWESIDSKKNIEEIINKISNVYSVESNKITKDI
                     KNYLKDLEKNGLIE"
     aSDomain        10082..10249
                     /aSDomain="Stand_Alone_Lasso_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="Stand-alone RRE protein in a lasso peptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_JS609_RS18070_Stand_Alone_Lasso_RRE.1
                     "
                     /evalue="6.00E-14"
                     /identifier="RREFam002.1"
                     /label="JS609_RS18070"
                     /locus_tag="JS609_RS18070"
                     /protein_end="83"
                     /protein_start="27"
                     /score="42.8"
                     /tool="antismash"
                     /translation="ILDDVGVNIWESIDSKKNIEEIINKISNVYSVESNKITKDIKNYL
                     KDLEKNGLIEV"
     misc_feature    10313..10331
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: medium, score: 24.02"
                     /tool="antismash"
     misc_feature    10421..10439
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: medium, score: 24.02"
                     /tool="antismash"
     gene            10591..11217
                     /locus_tag="JS609_RS18075"
                     /old_locus_tag="JS609_03561"
     CDS             10591..11217
                     /EC_number="3.4.-.-"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0071586 - CAAX-box protein processing
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abi"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF014566.3"
                     /locus_tag="JS609_RS18075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JS609_03561"
                     /product="CPBP family intramembrane glutamic endopeptidase"
                     /protein_id="WP_080529864.1"
                     /sec_met_domain="Abi (E-value: 1.6e-10, bitscore: 39.2,
                     seeds: 823, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLLEEVFTYIVLFVIVKTCMFLIRKIRGNLLFDVLRNLLFFVPFI
                     LPALYLGLPNLIFQGSINYYLLSIFSSFLALSIKYKEFKPYFNKNFYQILPKISFKDFL
                     ILEISLIGSAIFEEFFYRSFAPHSSFIVGMALSGILFSIAHYIQNYTRSFFDLKTYILL
                     FLLGMVWYWSYKNTGTLIPAILGHLVYNLPSMIFTYFHFKSSRFR"
     gene            11238..12044
                     /locus_tag="JS609_RS18080"
                     /old_locus_tag="JS609_03562"
     CDS             11238..12044
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013245.3"
                     /locus_tag="JS609_RS18080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JS609_03562"
                     /product="ABC transporter permease"
                     /protein_id="WP_080529865.1"
                     /transl_table=11
                     /translation="MSRIIIATIKRNYIVSKRVFPWSFIIARVLMGIYVSVFAFFTFKY
                     MFDGKTESHFLKYSNGIDYISFVVLGAGLYTYSISVIMNVGRSLMLENIEGTLESILVS
                     PCSRLGYFLGVFFEQIGRSSLEFLIVIFFSLYLGANIEIENTIPLLIVIIITTISLFSI
                     GIFIATLMLFLRDTYITQNTLFIVMGLVSGVSFPREYLPNILYYLSYLSPLSYALSLFR
                     GVMTGQNILNYTKEILDIFVLSLAYCLFGLLWLKCLEKKILENTFN"
     gene            12057..13064
                     /locus_tag="JS609_RS18085"
                     /old_locus_tag="JS609_03563"
     CDS             12057..13064
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016201577.1"
                     /locus_tag="JS609_RS18085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JS609_03563"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_138322659.1"
                     /transl_table=11
                     /translation="MLIAKDISKTYILNERKGFFIKKKTEINALKKLNLTIKPGSIVGL
                     LGVNGAGKSTTIKILSTILAPTTGSLKVNEVDALKYPVEAKKLLNVITGGERNLYWRLT
                     ARENLEYFGALYGLSKKELKDYIPSSLSLVGLKDSNIPVERYSKGMKQRLQIARGLVNN
                     PKYLFLDEPTLGLDINIAKDLRQYIKKLAHQKNKGILLTTHYLSEVEELCDWVYIIDKG
                     NLLTEGTPSDIVSKIIPEIQLKIELSNLSCELKKELLYYVGAIDAKIHFFKDHTNYSIL
                     LSSKDDLTSDLVNIITKYRTSILSFKTEEPNLEDALLTLTSKQGDSIYELVKGN"
     gene            13042..13851
                     /locus_tag="JS609_RS18090"
                     /old_locus_tag="JS609_03564"
     CDS             13042..13851
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024110.3"
                     /locus_tag="JS609_RS18090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JS609_03564"
                     /product="ABC transporter permease"
                     /protein_id="WP_080529866.1"
                     /transl_table=11
                     /translation="MNWLKVIKAEIYKQHKNSFHSTKAYFSLLIWPILNLINAYLCYKP
                     FNLNDLKLYRINTSDELISFLLIGFFTYISFKSLMQSALQMSYERSNGTLETIFLSPAN
                     RLSLIYGRSLGFIFGNIWMFFAFTFFIMCYIGSIPIYNLVYFPICFILIVISATLWGGL
                     LNTIFLFSRDASILFMIIDDPMMLFSGVRIPLTLFPIWAQVISFIFPLTHVLAVVRDLM
                     LFGDISLSSWNHLLYLLSELLFMYMITLFLLSKAEKHARINGELTFY"
     gene            complement(14039..14377)
                     /gene="cccB"
                     /locus_tag="JS609_RS18095"
                     /old_locus_tag="JS609_03565"
     CDS             complement(14039..14377)
                     /codon_start=1
                     /gene="cccB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391407.1"
                     /locus_tag="JS609_RS18095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JS609_03565"
                     /product="cytochrome c-551"
                     /protein_id="WP_080529867.1"
                     /transl_table=11
                     /translation="MKSKLSILMLVFTLSVLLAACGSNDAKEEKTDTGSKTEASASEGE
                     ELYQQSCVGCHGKDLEGVSGPNLQEVGGKYDEDKIESIIKNGRGNMPKGLVDDKEAAVI
                     AKWLSEKK"
     misc_feature    complement(14358..14372)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: medium, score: 20.1"
                     /tool="antismash"
     gene            complement(14426..15271)
                     /gene="yvjA"
                     /locus_tag="JS609_RS18100"
                     /old_locus_tag="JS609_03566"
     CDS             complement(14426..15271)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /gene="yvjA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019715868.1"
                     /locus_tag="JS609_RS18100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JS609_03566"
                     /product="YitT family protein"
                     /protein_id="WP_003242677.1"
                     /transl_table=11
                     /translation="MDVRNKTLWILRDYVYILIGAAITAVSFNVFLLPNKIAAGGVSGI
                     STILQSYGFEAAYVQWIINIPLFIAGVILLGGKFGLKTLAGSVFLPLVVFLTRDIQPAT
                     HHELLAAIFGGVGIGIGIGIVYLGKGSTGGTALAAQIIHKYSGLSLGKCLAIIDGMIVV
                     TAMIVFNIEQGLYAMLGVYVSSKTIDVVQVGFNRSKMALIITKQEQAVKEAVLQKIDRG
                     VTKISAVGGYTDDDRPILMCVVGQTEFTKLKQIVKQIDESAFVIVADASEVLGEGFKRA
                     "
     gene            complement(15437..16538)
                     /gene="prfB"
                     /locus_tag="JS609_RS18105"
                     /old_locus_tag="JS609_03567"
     CDS             complement(join(15437..16465,16467..16538))
                     /GO_function="GO:0003747 - translation release factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="prfB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391409.1"
                     /locus_tag="JS609_RS18105"
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="JS609_03567"
                     /product="peptide chain release factor 2"
                     /protein_id="WP_010886623.1"
                     /ribosomal_slippage=""
                     /transl_table=11
                     /translation="MELSEIRAELENMASRLADFRGSLDLESKEARIAELDEQMADPEF
                     WNDQQKAQTVINEANGLKDYVNSYKKLNESHEELQMTHDLLKEEPDTDLQLELEKELKS
                     LTKEFNEFELQLLLSEPYDKNNAILELHPGAGGTESQDWGSMLLRMYTRWGERRGFKVE
                     TLDYLPGDEAGIKSVTLLIKGHNAYGYLKAEKGVHRLVRISPFDSSGRRHTSFVSCEVM
                     PEFNDEIDIDIRTEDIKVDTYRASGAGGQHVNTTDSAVRITHLPTNVVVTCQTERSQIK
                     NRERAMKMLKAKLYQRRIEEQQAELDEIRGEQKEIGWGSQIRSYVFHPYSMVKDHRTNT
                     EMGNVQAVMDGDIDTFIDAYLRSKLS"
     gene            complement(16608..19133)
                     /gene="secA"
                     /locus_tag="JS609_RS18110"
                     /old_locus_tag="JS609_03568"
     CDS             complement(16608..19133)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006605 - protein targeting [Evidence IEA]"
                     /GO_process="GO:0006886 - intracellular protein transport
                     [Evidence IEA]"
                     /GO_process="GO:0017038 - protein import [Evidence IEA]"
                     /codon_start=1
                     /gene="secA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391410.1"
                     /locus_tag="JS609_RS18110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JS609_03568"
                     /product="preprotein translocase subunit SecA"
                     /protein_id="WP_213382313.1"
                     /transl_table=11
                     /translation="MLGILNKMFDPTKRTLNRYEKIANDIDAIRGDYENLSDDALKHKT
                     IEFKERLEKGATTDDLLVEAFAVVREASRRVTGMFPFKVQLMGGVALHDGNIAEMKTGE
                     GKTLTSTLPVYLNALTGKGVHVVTVNEYLASRDAEQMGKIFEFLGLTVGLNLNSMSKDE
                     KREAYAADITYSTNNELGFDYLRDNMVLYKEQMVQRPLHFAVIDEVDSILIDEARTPLI
                     ISGQAAKSTKLYVQANAFVRTLKAEKDYTYDIKTKAVQLTEEGMTKAEKAFGIDNLFDV
                     KHVALNHHINQALKAHVAMQKDVDYVVEDGQVVIVDSFTGRLMKGRRYSEGLHQAIEAK
                     EGLEIQNESMTLATITFQNYFRMYEKLAGMTGTAKTEEEEFRNIYNMQVVTIPTNRPVV
                     RDDRPDLIYRTMEGKFKAVAEDVAQRYMTGQPVLVGTVAVETSELISKLLKNKGIPHQV
                     LNAKNHEREAQIIEEAGQKGAVTIATNMAGRGTDIKLGEGVKELGGLAVVGTERHESRR
                     IDNQLRGRSGRQGDPGITQFYLSMEDELMRRFGAERTMAMLDRFGMDDSTPIQSKMVSR
                     AVESSQKRVEGNNFDSRKQLLQYDDVLRQQREVIYKQRFEVIDSENLREIVENMIKSSL
                     ERAIAVYTPREELPEEWKLDGLVDLINTTYLDEGALEKSDIFGKEPDEMLELIMDRIIT
                     KYNEKEEQFGKEQMREFEKVIVLRAVDSKWMDHIDAMDQLRQGIHLRAYAQTNPLREYQ
                     MEGFAMFEHMIESIEDEVAKFVMKAEIENNLEREEVVQGQTTAHQPQEGDDNKKAKKAP
                     VRKVVDIGRNAPCHCGSGKKYKNCCGRTE"
     misc_feature    complement(19158..19174)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: medium, score: 23.45"
                     /tool="antismash"
     gene            complement(19301..19870)
                     /gene="hpf"
                     /gene_synonym="yvyD"
                     /locus_tag="JS609_RS18115"
                     /old_locus_tag="JS609_03569"
     CDS             complement(19301..19870)
                     /codon_start=1
                     /gene="hpf"
                     /gene_synonym="yvyD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391411.1"
                     /locus_tag="JS609_RS18115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JS609_03569"
                     /product="ribosome hibernation promotion factor"
                     /protein_id="WP_003228031.1"
                     /transl_table=11
                     /translation="MNYNIRGENIEVTPALKDHVERKIGKLERYFDHSVDADVNVNLKF
                     YNDKESKVEVTIPMTDLALRSEVHNEDMYNAIDLATNKLERQIRKHKTKVNRKFREQGS
                     PKYLLANGLGSDTDIAVQDDIEEEESLDIVRQKRFNLKPMDSEEAILQMNMLGHNFFVF
                     TNAETNLTNVVYRRNDGKYGLIEPTE"
ORIGIN
        1 agcttttctc tatctacttt ttctacgtac tcattcgata ttaactcata cgctttttcg
       61 attttgtcca tagctttatc ccgttcagag tcagcttgtg ccgtcgcggg aactgctgca
      121 gtctggggct tatccatctc aagcaggttg attcccgcat atacaccgac gcctccgaac
      181 agcatgctcc ctgctgctat cacagccatt attttttgat tcatccttta ctcctcctgt
      241 atgccagact gtctttacca aaacctagag atagtatatg taaaggatgg agatttcatg
      301 taatcataga agaaaaagaa ggcaaatgaa aagccgtccc gaaaacggaa cggctttttc
      361 actttatact cgcaaaaact tgcggatgga agtcagactt ccccatactc caattactgc
      421 gccgattgca atcagcacta gcgaaacttg gaatacaaat ggattataag gaagaagaga
      481 gacaaatgat ccttgaacct ttggaacgac ccatccgatg acgtattggt aagtgctcag
      541 caccagtgca atcggaatca cagaaccgaa tacgcctagc agcaatcctt caaggaaaaa
      601 cggccagcgg ataaaccagt ttgtcgcgcc gacaagcttc atgatttcaa tttcttttct
      661 tcttgcgaaa attgtaattt taatggtgtt ggaaattaag aacatcgccg taaataccag
      721 gccgataatt aacgcgattc cgatgttgcg ggaaacgccg accactttaa acaaacggct
      781 gacctcttct tttccataag tgactttata aacatgatcc attttttcga tctttttcgc
      841 cacgttcggc gtatcatgcg gatctgtcgt tttgacgaca aacgcatcat taagcgggtt
      901 ttcctgatcc ttcattgtca gggattttcc gctgtcacca aaactgtcaa ccagctggtc
      961 aagctctttt tctttagatg aaaaagtgac actctgaatg cccttcagtt ccttaatatc
     1021 gttctgaagc ttgtcctgtg ccttctgatc tgcagtcaga tcaaccagca ctttgatttc
     1081 gacttgtttt tctgctttcg tggccatgtt attcaaattc agcataatca ctaaaaacac
     1141 gccgactaaa atcagcgtaa cggttacagc actaatggat gcaaatgtca tccatgtgtt
     1201 tctcccgaga gatttaaaac tctcacgcaa gtggcgcccg agaattttaa tcatatgaac
     1261 catactcccc tcttgactca tcacgcacaa tgataccatc ttcgattgca atgacacgtt
     1321 tcttcatggt gtttacgatt tctttattat gtgtcgccat cacgactgtt gtcccgcggt
     1381 tattaacttc ctccagcgtc ttcatgactt cccaggacgt atccggatca aggtttcctg
     1441 tcggttcatc agcaatgaca acatcagggt tgttcacaat tgatctggca atagatacac
     1501 gctgctgctc cccgcctgaa agctggtcag gaaattgtcg cgctttatgc ttcagctgca
     1561 cgagatcaag cacttcaagc acccgtttct taataacaga cggctgttct ccaatcactt
     1621 caagggcaaa tgccacattt tcaaaaacag taagtttcgg aagaagcttg aaatcctgaa
     1681 agacaacgcc tattttgcgg cgcacgaaag gaatctcttt ttctttaatt gtcgcgagat
     1741 ctttatgatt gattaaaatt tgtccttttg tcggtttttc ttctctgtaa atcattttaa
     1801 taaaagtaga tttacccgct ccgctcggcc caacaacata cacaaactca ccgggatgaa
     1861 tggtaacaga aatcccattg agcgctttta cgccgttcgg ataggcttta tatacttcct
     1921 tcatctctat catgaaatca cctaatcttt tatatcattt tatctatcac acggtcatac
     1981 tcttcgaatg cattcgacaa tttatgatcc attcatttgt aaaaagatga aaaatctgaa
     2041 agttcccttt ttcaatacac ttcattatac gtcaaattta gacataatac tattacagtt
     2101 tcttttcatt catatttaaa gaataaatat tcatttgggt tggaagtttc gtttattacg
     2161 aaaactgttt ttccatttaa atgaatcaaa tccactactt gacaatcatt gataaataat
     2221 ataaaatttc gtcaaaatta cttttttgta tattaatgtt aatatatcca taaaaatgaa
     2281 cttggtatca ctctcaactt gttatctcat atttacataa tctaagtaga cacgaactaa
     2341 cagaaaaaca tcattaattt atttaagggg tgttataatt gaagctaatt tacaaggacg
     2401 aatacggtcc tctatattct gaaaagtcaa agaattctat ccttaaagag cctacttatt
     2461 ttgaagttga ttccaaagac aacttaaata gaattgttga taaaaaagga cattacactt
     2521 atcaaaacaa taagcttcat aagataaaac ctaaaaatat aggtgcatct ggcagtaata
     2581 gtggataccc tctcattatg gataaaaaag gacactcctt ggaatatggt agagaccttc
     2641 ttgaagtatc aatgagaaat aaactttata ttaggaccac agaaaaagaa tattgttatg
     2701 agtacgatac cgaagttgaa ccagatacta ttcaaatttt tgatgacaaa gtgcttttga
     2761 atttaaaatt aagacaaatg gttgtacttg tatctacttc aggtaaagtt ttaaatagct
     2821 ttggtcttga tagatacaga ggtgaaggac aaaaacaatt aaatgttccc atgttctctg
     2881 tatatataga agatagaaat tctatattaa tttcagatgc cattaattca agagtaattg
     2941 aagtcgacga aaatggaaat ataatttgga aatatggaaa ggatggttta ttaggttcgg
     3001 atcaaggact cttatggaaa ccaacttgcg caagaagact ttccaatggg catactatta
     3061 ttgcagattc caaaaataac cgattagtta ctatagatca agataaaaat attgtaaatg
     3121 agattgggca aacaaatgtt tctaaattgt ttctcacata tcctcgctct gttcaaatgc
     3181 ttgataaata taattggctg gtgacaaata cacacaagaa ttctatcttt atcatgaatc
     3241 aaaatcaaaa gaaaatcata aaacccataa atgattctta taacaagtta aatttatttt
     3301 ggccaagatg tagtataaaa aactcggatg atgaaataat catagcggac ggaaagaata
     3361 atagaataat gtttattgac gataaaacat tacaaataaa aaaagtaatt gattactatt
     3421 atgaacaagg taatagaatg acaattattg atcctcatga tattaaaata aaccctaaaa
     3481 caaaccttct tctcattacc ttatctggaa acaatagggt tatagaaatg actagtgatg
     3541 gcgagttaat tgagagctat gataatctaa acgaccctca ttctgcttat tacttttcaa
     3601 atgggattat tattgctaat acggaagaca acaacatagt tatttattat ttttccggca
     3661 aaaaagaaat cattaataat tttaaatcta ctaattcatg ctgtgatgcc tttaagagac
     3721 ctcgttatgc gctaccttat aaaaatggat ttctaatatt agatacagac aatcaaagaa
     3781 ttatattttt aaaaaaagag aataacgaat ggattggaga aaatgtgcct atctattttc
     3841 ctgatggacc tataatgaat tatctttgtt ttcctcggtg cattacattt aacaatgata
     3901 atgaactaat cttaaccgat actgaaaatt gtaggatttt acgccttgtg attgacgaca
     3961 ctcttattaa ggaggagcat tcaaatgaaa tataaagttg attcggcaca tggtggtgaa
     4021 ggttgggtac ctagaaagca agatcactct acagaactag gtcatttctg gaataactgt
     4081 ggcgtaaagg gcgaattcgg taccctgtca catgttttac ttagaagtcc aggtctagag
     4141 gtagaacaaa attttaatcc tgctgatatc ctatggactg agagaataga accatcgaaa
     4201 gcaagagaac agcataataa tcttattgaa gtttatcgct cccaaggggt agaagtagac
     4261 ttaattgatg ataaagcagc tgaatctttt ccaaatattt tgtatgtcag agatttgttt
     4321 acaatgacag atcaaggagc aatcctatcc aggatggcat cagaggttag ggctggagaa
     4381 gaagtaatta tttctaaaaa actatctgaa ctcggtatac ctattttagc ctctcttcac
     4441 tcggatatga tattagaagg tccagacata ttaatagtca atcctgatct agtatttata
     4501 ggttatggta taagaacaaa ttataaagca gctatgtatg tcaaacagat actattagga
     4561 ttgggatatt ccgaagttat catcattcaa actacttatg gctgcggaca cttggatggt
     4621 gtagtgaata ttttaaattc tcggtatgct gccattgttc caaaaagagt ttcatatgag
     4681 ttgtacatag gattaaagag gcatgggttt tcaattattg aacttgacga catgtatgaa
     4741 atagatcagt tgatgtcaat taatttcgtt cagctaaacg aagagactct tctgattaat
     4801 aagggtgcca aaaatacagt gtctcaatat agctcatgtg gctttgaatg tctagaaata
     4861 gacattagtg aattaacaaa aggaggcggc tcaattcatt gtttaacagg gattttaagg
     4921 aggatttaac gagatgggcg tttctatagt aattccaatt aaagttaact caatcgatga
     4981 aatatatatt gatttcatca attacatcat tgatttttct tccaatgtat taactaaaga
     5041 cgttgaaata ataatagcca atggaagttc taaaaatatt tatatatttg ctaatgaaca
     5101 tcttaaacat ttgaaaaatg ttatacattt tatcccacat cgttcaatta gaacaggaga
     5161 caacgataaa ctaaacggga tatactctgc tttaatgtac actaagcatg ataacatttt
     5221 attagttgat gatcactata gagtatcaag tgaaacgctt gcagatatat taaaatacta
     5281 tgaaaaatat gattgtttta agtttatgcc taaactacat caatacccac attcagcttt
     5341 aattgataca tgtggaatgt ttattgttaa tgtattagat agtagaaagc aatattgcgg
     5401 ccatttagcc tttaaaaaaa gtttatatag tgaatgggga tttatcaata gagattctct
     5461 atttgatgag tttgctatgg aaaaacattt acgaaaaaag ggaagcagag tcggatttat
     5521 aaaagatatc gctctggaag ccaaacaaga aattccgttt aaaaaatttc ttgagcagag
     5581 agtacgttat gcttatgaaa acattgctac tccctatcgc tttacctttt tcgccatgat
     5641 cttaccactt ttaatactgt taagcctgat agacacgaac tatggtctga attttgcatt
     5701 ttttctaaca agctggacct ttgtcatatc aatagtaggt caattcattt atggtaaaca
     5761 aatcacccct tggtacactt cactatatag tcctatttgg ttctggtttt atccttttac
     5821 tacgtggata gcaatttaca agtaccttac cggaggaatc atgtttggcg ggaataatat
     5881 taggagggca ggatagatga aaatcactca aaagattata gggccacaaa gtattgtata
     5941 cttcaaaaaa gataaaaata gagaatttgt tgaaaaaatt tccactgaac gaggagaaga
     6001 tgaattagtt gatcaaattc acttttataa aatgttacca aaagagatta agcctctttt
     6061 tccagcccta tatgattatg atattaaaaa caggccgttt cgcatgtcaa tggaattatg
     6121 tgattttcca acattaaaag agattatttt atacaatact aagcaaaaca agttgaagga
     6181 acacttatat aatgttatac aggacatatt tgaaaaaata cacaacttaa aacaaacaca
     6241 ggcaacaaaa aattatgtag aacatttgta tatagatcgt tgcgtcaata gaataataga
     6301 aacaaagaaa ttaatgaaag aagcacaatg gataaacaac gacttttact tagagggttc
     6361 aattgtatcc aacccaattc aaacggtttt tgaaattata aataataata aggatttatt
     6421 aatacctgaa tatctatgca ctgtacatgg acagctaggt ccttctcact taatgttaaa
     6481 cattcaaaag aagaatagtt acaaactagt tgatccaaag ggatttcatg aatttcatga
     6541 tccattgttg gatattataa aaataggtag gtccttcctc tatgggatgg agtggttaga
     6601 agatgacttg tataatatta aatattcttt taaaaatgaa tatcttacaa tagaagattt
     6661 taatttaatt aactatgatg aagtatatat gaagaagtca tttaaaccta taatggattt
     6721 agccataaat aattacaaaa atgctgccct aagagtatat gccttaattt gctgtgatct
     6781 aatagcaaat ttaccttttg catatttatc aggtggtgaa aagagagtag tagctttata
     6841 taatctcata tatgctgcta gtttagattt gtctcaatta aatgatgctg taaataagga
     6901 gaaacatata tatgaaagtc tttcaaaata acagatataa tatatttaat tacaaggaaa
     6961 gttctatctt tatagaagat agacaacccc attctgttct tacaatagca aatttaaaaa
     7021 atcaattagt tgtggtgaga caaatgcgaa aaggaataaa taatgaaacc gtcgaattgc
     7081 ccgggggaca ggttgaagat aatgaaaaac ctatggacgc agcaaaaaga gagctagagg
     7141 aagaaactgg actaatagca aatcaattta ttcaaatagg taatatttat cctctcccta
     7201 gtttaattaa tcgccaaatc acatattttt atactgaaaa tattgttggt tataataaga
     7261 ctattaaaca ggatgaagat gaaaatatac atgtagaata tcacaaattt ccaaaagtcg
     7321 agtataatct taaaacccaa aagtggaggg atcaatttct tgcttatgga gtatatatct
     7381 gcaaattgaa aggaataata taaaaatttt agaggttaaa aatggatgtc caatctatat
     7441 tatttgatct tgataacact ttgttaaata gacaaaaaac ttttgaaaat tatttagatt
     7501 catttatctc caagtatatt ttctataact ccccgaccga aaagaaagat ataaaaaata
     7561 aaataataga tatggataaa aagggagaaa aagataaaaa ggaattgttt tcagaattac
     7621 aacatagatt aaagtggaga ttaacccctt ccgttgatta tttagttgaa gaatataaaa
     7681 caatattcgc aaaaaacagt atagttatgg atggaacttt tgaggttcta acattttgca
     7741 agaataaaaa tttaaaatta gggattataa ctaatggaga atcattttat cagaagatta
     7801 aactaaataa cacaaacctt acatgttttt ttgattttat cttaatctca gaggaattcg
     7861 gtaaagctaa gcctcatcgc tctatcttta aattcgctat tgataagatg gccattgatc
     7921 cacgaaaatc aattttcatt ggagacaatc ttatttctga tatttatggt gcttctaggt
     7981 ttggatttta tactgtttgg tataatcact ctaatatagt caaacaaaat cccataactg
     8041 taaaacctaa taaaattata actagtttaa gtgaattgtt gaaaataaaa gactggtagc
     8101 cgaaaggaga aaaaagtgat tattagtgtt gattttctaa atcatttaca cagtatttat
     8161 aataaaaata acgatctatc cgaaaatgtt aaaagaatat tcaaagaata taaatgcagt
     8221 aatatttatg aacacagtgt aagggtagca catatggcaa aaaaattagc tgtacggttt
     8281 cgagccaatg aagaatcagc atatatagca gccttattac atgatattgg aggtattgtt
     8341 cctaatggaa aaagaattga aattgccaat atactaaaaa tccctctttt tcctgaagag
     8401 atagagttcc cactaattat tcatcaaaaa atctctaagg ttattgctga aaaagttttt
     8461 ttaataagtg accattctat tcttaatgcg atagaatgtc atacaacttt aaagtcgaac
     8521 cctagtatgt tggataaaat tgtatttata tcagacaaaa ttgaatggga tcaaaagggt
     8581 tctcctcctt acataaatag tctaatagaa gccttagatg tttcaattga ttgtgcttca
     8641 aatgtctata ttaagtttct tatggaaaat aaaaataatc taaaggttat tcacccttgg
     8701 cttagtgact cttataacta ttttaaaaaa taaccctcaa ctcaatacta tatataatat
     8761 tatgtattta aatccatcaa agttgtgtaa atattggcaa gattctctta agatagcctt
     8821 gtattttttg tttaacactc ttagacctag gattaataac tgaaatatta atggtctaag
     8881 agtgttgatt atattgaacg attaattaac atgttttatg tcggaaacaa ggcattcaat
     8941 ttacactatt atctttattt accttattaa actaatatat attctattcc cccccctgat
     9001 tcacatccaa tcgaactaag tcttggttga atgctttaat tttattaatt ctttttataa
     9061 tgaataacta taaacaatat tattagtgta gaagattaaa taatttcatt tttattacaa
     9121 tatgaattaa taattgtttt tcaaaaaatt ccatgttata atttggtaaa ccactgaaat
     9181 ttaaggaggg ttttatgagt aaagtatttg ataaagaaga aatccttaaa ttgattccgt
     9241 gttctgacaa aattgactat atatacttag cggggtcaat aatggaaggt ttcggaaatg
     9301 atgcttcaga tattgatgtt tttgttataa gtgaaaatcc agatagacta gcttatgaac
     9361 ctactaattt tacaagagaa gtaaacatac aagtaggaga atcattcata aaaaatattg
     9421 ttatagacag tattagatat gattttgagt actatcgttc ttctagtttt acttctttaa
     9481 tagaaaagtt gaataatttg aattttaata cagaaaatta tattccaagg tttacagcag
     9541 atgaaataga tcttttacat agattaaaat ttgctgagcc gcttctgaat aaaagtgctt
     9601 ttaatactat tctaaacaat ataaattttg aaaatttaaa taattattta gtaataacta
     9661 atattgagtc atatgatgga catttagaag acttacaggg agctctttct tgttctgatt
     9721 ttggtacttc atttgtgctt ttaaaattat tattaaaata ttctcttaat gcttatttag
     9781 cgaaatatgg agagacaaat ccaggagaaa aatggttatt tagaaaatta agtagatacg
     9841 ccgaaaaaca tggtgatcaa catttacttg ataagtatct taatttatta tgttatcctt
     9901 ttgagaaaga taatatcaaa cattatgctc aaaaaactat taattttact caaccattaa
     9961 ttatcaaagc tcaaaaataa aaacggaggg aagtaatcac atgatttatc aaaaaaatat
    10021 gtttgtgaga ttccgtatca tcgatactaa accttatctt attcttaatg acaatgcatt
    10081 tatcttagac gatgtaggcg ttaatatttg ggaatcaatt gatagcaaaa aaaatattga
    10141 agaaataata aataaaatct caaatgttta ctcagtagag tctaataaaa taactaaaga
    10201 tattaagaat tatttaaaag atcttgaaaa aaacggatta attgaagtgt gtaaagaaat
    10261 ctcataggta gttaataatg tctggaatgg gctcctttag tggaggtgag attaatgtat
    10321 aaaaagcctg tattaattaa ggtgaagctt cctgttgcgt tagagtttgt ttaattacta
    10381 cttaactgat tgacctatct tttatgaatt gaggtgagat taatgtataa aaagcctgta
    10441 ttaattaagg tgaagcttcc tgttgcgtta gagtttgttt aaatctaaaa ccagactaaa
    10501 ataattgatc aaaaaatcaa aggagcccat ccctaacatt attattaaat caacaactac
    10561 tcataaaatt ttaggagtaa ggtatacatt atgctattag aagaagtttt cacgtatata
    10621 gttctttttg ttatagttaa aacatgtatg tttcttataa ggaaaattag gggtaatctt
    10681 ttatttgatg tgctaaggaa tttattattt ttcgtccctt ttattttacc agcactttat
    10741 ttaggcttac ctaatttaat ttttcaaggt tcgattaatt attatttatt atccattttt
    10801 tcatcatttt tagctttaag cattaagtat aaagaattta aaccttactt caataaaaat
    10861 ttttaccaaa tcctcccgaa aatttctttt aaagactttt taatattgga aatatctttg
    10921 ataggaagcg ctatttttga agagtttttt tacaggagtt ttgctcctca ctcctctttt
    10981 attgtaggca tggcattgtc aggaatccta tttagtattg ctcattatat acagaactat
    11041 acaagaagtt ttttcgattt aaagacatat attttattgt ttttattagg aatggtttgg
    11101 tattggagtt ataaaaatac tgggacttta attccagcaa ttttaggtca tttagtatat
    11161 aaccttccta gtatgatttt cacctatttt cactttaaat catcaagatt tcggtgagga
    11221 aaaagggggt tataatagtg agtagaatca taattgcaac tataaaaaga aattatatag
    11281 tttcaaagag agtttttcct tggtctttta ttatagccag agttcttatg ggaatctatg
    11341 tttctgtatt tgcttttttt acttttaaat atatgtttga tggaaaaaca gaaagtcatt
    11401 ttttaaagta tagtaatggg atagactata taagctttgt agttctagga gccggtcttt
    11461 atacatattc tatatctgta ataatgaatg taggtagatc tcttatgtta gaaaatatag
    11521 aaggtacttt agaaagtata cttgtctcac cgtgttcacg tttagggtac tttttaggag
    11581 ttttttttga acaaataggt agatcaagtt tagagtttct aatagttata tttttcagtt
    11641 tatatttagg tgccaatatt gaaattgaga acactattcc acttttaata gtaatcatta
    11701 ttactacaat atctcttttc agtattggta tatttatagc tactctaatg ttatttctac
    11761 gcgacaccta tataacacag aatactttat ttatagttat gggattagtt agtggagtat
    11821 cttttccgag ggagtactta cctaatatcc tctactattt atcctatttg tccccattat
    11881 cttatgcact ttctttattc cgaggtgtta tgacaggaca aaacatttta aattacacaa
    11941 aggaaatctt ggacatattt gtcttgagcc tagcttattg tctttttggt ttactttggc
    12001 ttaaatgtct ggaaaaaaaa atattagaaa atacatttaa ctaagggtga tagtaaatgc
    12061 taattgccaa ggatattagt aaaacttata tattgaatga gagaaaaggt ttttttataa
    12121 aaaaaaaaac agagattaat gccttgaaaa agctgaactt aacaattaag ccgggtagta
    12181 ttgtagggtt attaggagtt aatggcgcgg gaaaaagcac aactattaaa atattatcga
    12241 ccattctagc gccaactact ggctccttga aagttaatga agtcgatgca ttaaaatatc
    12301 ctgtagaagc aaaaaaattg ttaaacgtaa taactggtgg tgaaagaaat ttatattgga
    12361 ggttaactgc tagagaaaac ctcgaatact ttggagcatt atatggacta tctaaaaaag
    12421 aacttaaaga ctatatacca tcatcactta gtttggttgg attaaaagac tcaaatatac
    12481 cagtcgagag atattcaaaa gggatgaaac aaagattaca aattgctagg gggctagtaa
    12541 ataatcctaa atatttattt ttagatgaac ctacattagg cttagacata aatattgcaa
    12601 aagatttaag gcaatacata aaaaaattag ctcaccaaaa aaacaagggg atattattaa
    12661 ctacccacta tttatctgaa gttgaggagc tatgcgattg ggtttatata attgacaaag
    12721 gaaatttgct cacagaaggc actccttcag atattgtatc aaaaataata ccagaaattc
    12781 aattgaaaat agaattgtca aatctaagtt gtgaattaaa aaaagaatta ttgtactatg
    12841 ttggtgcaat agatgctaaa atacattttt tcaaagatca tactaattac tcgattttat
    12901 tatcatcgaa agacgattta acttctgatt tggttaatat tataacaaaa tacagaactt
    12961 ccattctaag ttttaaaacc gaagaaccta atcttgagga tgcattatta acattaacaa
    13021 gtaaacaagg tgattcaatt tatgaattgg ttaaaggtaa ttaaagctga aatatataaa
    13081 caacataaga attcatttca ttcaacaaaa gcttattttt cattattaat atggccaata
    13141 ttaaacttaa ttaatgccta cttatgttac aagcctttta atttaaacga tttaaaatta
    13201 tatagaatta atacatctga cgaattaata tcctttttat taataggttt tttcacttat
    13261 atttctttta agtcgttaat gcaaagtgct ttacaaatga gttatgaaag atcaaatgga
    13321 actttggaaa caatattctt atccccagca aatcgtttat cattaatata cggaagaagc
    13381 ttaggattta tattcggtaa tatatggatg ttttttgcgt ttactttttt tataatgtgt
    13441 tatatcggat caatacctat atataattta gtctattttc caatatgttt cattctaatc
    13501 gtcatttcag caactttatg gggaggctta ttaaatacta tctttctttt ttctcgagat
    13561 gcttcgatat tgtttatgat tattgatgat cctatgatgt tattttcagg tgtgagaatt
    13621 cctctaactc ttttcccaat atgggcacaa gtaatttctt ttatatttcc tctcactcat
    13681 gttttagctg tagtcagaga cttaatgtta tttggagata tctcgttatc ctcatggaat
    13741 catttattat acttattatc agaattatta tttatgtata tgataacttt atttttgcta
    13801 tcaaaagctg aaaaacatgc ccgtattaat ggagaattaa ccttttattg aataggttaa
    13861 aaaaaagtaa aaaatactta attaaagtat tttttactaa atttatttct tatagtttat
    13921 tttttaaact acatgttttt tatactttta tttagcttga ttacattgtt aactaaggag
    13981 aaataccttt gtctaaaggt gtttctttcc ttagttaaca aatcaatctc caatcatctt
    14041 actttttttc tgacagccat ttggcaataa cggcggcttc cttatcatct acaagcccct
    14101 tcggcatatt gccgcggccg tttttaataa tgctttcaat tttgtcttcg tcgtatttgc
    14161 ctccgacctc ttgaagatta ggccctgaca caccttctaa atccttgccg tggcagccta
    14221 cgcagctttg ctgatataat tcttcccctt cagatgcaga ggcttcagtc ttgctgcctg
    14281 tatctgtctt ctcttctttt gcatcatttg aaccgcaggc agccaaaaga actgaaagcg
    14341 taaatacaag cattagtatc gataactttg atttcatgtt gagaagcaca actcctttac
    14401 gatctcttcc atattataac ctcgtttaag cacgtttgaa accctcgccc agcacctcac
    14461 ttgcatccgc cacaatcaca aaagctgact catcaatctg tttgacgatt tgtttcaatt
    14521 tggtgaattc agtttgccca accacgcaca ttaaaatcgg acggtcatcg tcagtatatc
    14581 cgccgactgc agagattttt gtcacgcctc tgtcaatctt ctgtaagaca gcctccttga
    14641 cagcctgctc ctgctttgta atgatgagcg ccatttttga acgattaaag ccgacttgca
    14701 caacatcaat ggttttgctg gacacataga cgccaagcat ggcatataag ccttgctcaa
    14761 tattaaatac aatcatagcc gtaacaacga tcattccgtc aatgatggcg agacacttcc
    14821 ccaatgacag accggagtac ttatgaatga tctgtgcagc caaggctgtt cctcccgtcg
    14881 atcctttccc taagtacaca ataccaattc cgatacctat cccgacaccg ccaaaaatcg
    14941 ccgccaggag ttcatgatga gtggcgggct gaatatccct tgtcagaaac actactagcg
    15001 gcaaaaacac agaacctgca agcgtcttta gtccaaattt cccgccgagc aaaatgacgc
    15061 cagcaataaa taaagggata ttaataatcc actgtacata cgctgcttca aaaccatatg
    15121 attgtaaaat cgtactgatc ccgctgacac cgccggcggc aatcttgttc ggaagcaaaa
    15181 atacattaaa ggacacggcc gtaatcgctg ctcctatcaa tatgtataca taatcccgca
    15241 aaatccacaa tgttttattc cgtacgtcca tcatatatcc tccgtttctt ccaatgctct
    15301 ccgatagcat tttaatcctt ccctgattag atgtaaataa cacccaaata cagtggtaat
    15361 atgctaaagc agcagtgaaa tcaaggatat aaggaattaa aaaaacacac ccgttgcatc
    15421 aggtgtgttt ttcagcttat gaaagcttag aacgcaggta ggcatcaata aacgtatcaa
    15481 tgtcaccatc cattacagct tgaacgttcc ccatttctgt attggtccga tgatctttta
    15541 ccatggaata cggatggaat acataagaac ggatttggct gccccagccg atttcttttt
    15601 gttcaccgcg aatttcatcc agctctgcct gctgctcttc aattctgcgc tgatacagct
    15661 tggccttcag cattttcatg gctctttcac ggtttttaat ttgtgagcgc tccgtttggc
    15721 atgtcacaac tacgttcgtc ggcaagtgag taatccgaac ggctgaatcc gtcgtattga
    15781 cgtgctgtcc gcccgcgccg cttgcacggt acgtgtcaac tttaatatcc tccgtacgaa
    15841 tatcaatatc aatttcatcg ttaaattcag gcatgacttc acatgaaacg aaagatgtgt
    15901 ggcggcggcc tgatgaatca aatggtgaga tccgcacaag acgatggaca cctttttctg
    15961 ctttgagata cccgtaagcg ttgtgtcctt tgatgagcaa tgtcactgac ttgattccag
    16021 cctcgtcacc tggaaggtaa tcgagtgttt ctactttaaa gccgcggcgc tctccccatc
    16081 ttgtatacat tctaagaagc atagagcccc agtcctgtga ctctgtaccg ccagcaccag
    16141 ggtgcagttc taaaatcgcg ttatttttat catacggctc gctgagaaga agctgaagct
    16201 caaactcatt gaactctttt gttaatgatt ttagttcttt ttcaagctca agctggagat
    16261 cagtgtccgg ctcttctttc aaaagatcat gagtcatttg taattcttcg tgggattcat
    16321 tcaatttttt atacgaattg acataatcct ttaaaccgtt tgcttcattt ataaccgttt
    16381 gagctttttg ctgatcattc cagaattccg gatcagccat ttgttcatct agctcagcaa
    16441 tgcgggcctc ctttgattcg aggtcaaaga gaccccctaa agtccgctaa acgagaagcc
    16501 atattttcga gctctgctct gatttctgat aattccattt cattcacctc attaaaagat
    16561 ccgcaggcgc ctgcacgcgc cgcggtcagt aaacttgccg gggcgaacta ttcagtacgg
    16621 ccgcagcaat ttttatattt tttcccgctt ccgcagtggc atggggcatt tcgtccgata
    16681 tcaaccactt tgcgaaccgg tgctttcttt gcttttttgt tatcgtcgcc ttcttgcggc
    16741 tgatgagctg ttgtttggcc ttgtacaacc tcttcacgct ccagattgtt ttcaatctca
    16801 gctttcatca caaattttgc gacttcgtcc tcaattgatt caatcatatg ctcaaacatc
    16861 gcaaagcctt ccatttgata ctcacgaagc gggttcgtct gcgcgtaagc acgaaggtga
    16921 atcccttggc ggagctgatc catcgcatca atatgatcca tccatttaga atcaacggca
    16981 cgaagaacga taactttttc gaattcgcgc atttgctctt tgccgaattg ctcttccttc
    17041 tcattatatt ttgtgatgat gcgatccata atgagctcaa gcatttcatc cggttctttc
    17101 ccgaagatat cgctcttctc aagcgcacct tcatcaagat aagttgtgtt gataagatca
    17161 actagaccgt caagcttcca ctcctcagga agctcttctc ttggcgtata gactgcaatt
    17221 gcgcgttcga gagaagactt gatcatattt tcaacgattt cacgcaggtt ttcagagtca
    17281 atgacttcaa agcgctgctt ataaatgacc tcacgctgct ggcggagaac atcatcatat
    17341 tgcagaagct gtttacgcga atcgaagtta ttgccttcga cacgtttttg tgacgattca
    17401 accgcgcgag ataccatttt gctttggatt ggagtagagt cgtccatgcc gaagcggtcc
    17461 agcatcgcca ttgtccgctc agctccgaat ctgcgcatca attcatcttc catagaaaga
    17521 taaaattgag taatccccgg gtctccctga cgtccggaac gacctcgaag ctgattgtca
    17581 atccggcgtg attcatgtcg ttctgttccg acaacagcga gcccgccaag ctcttttaca
    17641 ccttcgccaa gcttaatgtc cgttccgcgc cccgccatgt tagtcgcaat cgtaactgcg
    17701 cctttttggc cggcctcttc aatgatctgc gcttcacgtt catggttttt ggcatttaac
    17761 acttgatgcg gaattccttt gtttttaagc agcttagaaa tcaattcaga tgtttcaacg
    17821 gcaaccgtac cgacgagaac aggctgtccc gtcatgtaac gctgtgcgac atcctccgca
    17881 actgccttaa actttccttc catcgtgcgg taaattaaat ccggtcggtc atcacggaca
    17941 acaggcctgt tggtagggat cgtgacaacc tgcatgttgt agatgttgcg gaattcttct
    18001 tcctctgtct tagctgtacc cgtcataccg gcaagttttt cgtacatccg gaagtagttt
    18061 tggaatgtaa tcgtcgccaa ggtcatgctt tcgttttgaa tctcaagccc ttccttcgct
    18121 tcaatcgctt ggtgaagccc ctcactgtag cggcggcctt tcatcagacg tcccgtgaag
    18181 gaatcaacaa taacaacctg tccgtcttcc actacatagt caacgtcctt ttgcatcgca
    18241 acgtgagctt ttaaggcctg gttgatatgg tggttgagcg cgacatgctt cacatcaaag
    18301 aggttatcga tgccgaatgc tttttccgcc ttcgtcattc cttcttcagt aagctgtaca
    18361 gcttttgttt tgatatcgta cgtgtaatcc ttctccgctt ttaacgtgcg gacaaaagca
    18421 tttgcctgta cgtacagctt agtggatttt gcagcttgtc cagaaatgat aagcggtgtt
    18481 cttgcttcat caattaaaat agagtcaact tcatctatta ccgcaaaatg aagcgggcgc
    18541 tgaaccatct gctctttata aagaaccata ttgtcacgca aatagtcgaa gccaagctcg
    18601 ttgtttgtgg agtaagtaat atcagcggca taagcttccc gtttttcgtc ttttgacatt
    18661 gagtttaaat tcaaaccgac agtcaaaccg agaaactcga aaattttccc catttgctca
    18721 gcgtcacggc ttgccaagta ttcgttgaca gtcacgacgt gtacgccttt accggttaac
    18781 gcatttaaat aaacaggcag ggtagacgtt aatgttttcc cttcccctgt tttcatttcc
    18841 gctatatttc cgtcatgaag cgccacgccc cccatgagct ggactttaaa cggaaacatg
    18901 cctgttacgc ggcgtgaagc ttctcgaaca acagcgaaag cttcaacaag aagatcatcc
    18961 gttgtcgccc ctttttcaag acgctcttta aattcaattg ttttatgttt caacgcgtcg
    19021 tcagagagat tttcatagtc tccgcgaatc gcatcaatat cgttagcaat tttttcgtat
    19081 ctattcagcg tacgttttgt tggatcaaac attttattta aaattccaag catttataac
    19141 gctcctctat cttcacatgc ctattttaga ggcatgtata aataatttac tagtccatgt
    19201 atacctctca ttatcatatc ataccttttg ttatttccaa agaatttgca aataagaaaa
    19261 acaaaaacct tccgcggaca tcacggaagg cttctcttca ttattcagtc ggttcaatta
    19321 agccatattt cccgtcattt ctgcggtaca cgacatttgt aaggtttgtt tccgcatttg
    19381 tgaaaacaaa gaaattatgg ccgagcatat tcatttgcaa gatcgcttct tcactatcca
    19441 tcggctttaa attaaagcgt ttctgacgga cgatgtccaa gctctcctcc tcttctatgt
    19501 catcctgaac cgcaatatct gtatcagagc caagaccgtt tgccaataaa tattttggag
    19561 agccctgctc acggaattta cggtttactt tcgttttatg cttacggatt tgacgttcca
    19621 gtttgtttgt tgcgagatca attgcgttgt acatatcctc gttatgcacc tcggaccgaa
    19681 gcgccagatc tgtcatcgga atcgtaacct caaccttaga ctccttgtca ttgtaaaact
    19741 tcaagttgac gttcacatca gcatccacgc tatggtcaaa atagcgctcc agcttgccga
    19801 tcttcctctc gacatgatcc tttaacgcgg gtgtcacttc aatattttct cctctgatgt
    19861 tatagttcat caaagaacgc ctccctttta ttaaggatat gtatctattt ctcttttacc
    19921 ctttacaatt cctgctgaaa cataaatctt ttgtgaaaat tcagtgaact ttgtcgaatt
    19981 ttgtttgtat ttgctctgtt attggcggtt cggaggtata tgtatatgct gattgaacga
    20041 aacaaatacc tcacacacgc ctaattgatt aaaaagggtt ccatacattg atgaatagac
    20101 agcatccatt ttctataatg aatcagaaaa tgttccttta aatactcaca gaactcatga
    20161 gagggaaaag agaaagagac caattgatca aactccgcaa aaatttggtc aaatgctttc
    20221 acacaaattt cagcacaccg cgaatccata atgaagagaa gtgttga
//
