LOCUS       NZ_JAIONG010000039     18628 bp    DNA     linear   CON 22-NOV-2024
DEFINITION  Bacillus amyloliquefaciens strain SN_Endo51 sequence39, whole genome
            shotgun sequence.
ACCESSION   NZ_JAIONG010000039
VERSION     NZ_JAIONG010000039.1
KEYWORDS    WGS; RefSeq.
SOURCE      Bacillus amyloliquefaciens
  ORGANISM  Bacillus amyloliquefaciens
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Bacillaceae;
            Bacillus; Bacillus amyloliquefaciens group.
REFERENCE   1  (bases 1 to 18628)
  AUTHORS   Roy,M. and Dutta,T.K.
  TITLE     Community profile and biosynthetic gene analysis from end to end
            microbiomes of the medicinal mangrove Suaeda monoica Forssk. ex J.F.
            Gmel of Indian Sundarbans
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 18628)
  AUTHORS   Roy,M. and Dutta,T.K.
  TITLE     Direct Submission
  JOURNAL   Submitted (03-SEP-2021) Microbiology, Bose Institute, P-1/12, CIT
            Road Scheme VIIM, Kolkata, West Bengal 700054, India
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 30-MAY-2021
            Assembly Method                   :: SPAdes v. 25.05.2021
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 10.0x
            Sequencing Technology             :: Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_020179775.1-RS_2024_11_20
            Annotation Date                   :: 11/20/2024 08:35:12
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,314
            CDSs (total)                      :: 4,259
            Genes (coding)                    :: 4,097
            CDSs (with protein)               :: 4,097
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 46
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 162
            CDSs (without protein)            :: 162
            Pseudo Genes (ambiguous residues) :: 0 of 162
            Pseudo Genes (frameshifted)       :: 91 of 162
            Pseudo Genes (incomplete)         :: 72 of 162
            Pseudo Genes (internal stop)      :: 30 of 162
            Pseudo Genes (multiple problems)  :: 28 of 162
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 19:57:53
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 0
            Orig. end                         :: 18628
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JAIONG010000039.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     gene            <1..785
                     /locus_tag="K8B35_RS20510"
     source          1..18628
                     /altitude="4 m"
                     /collected_by="Dr. Madhumita Roy"
                     /collection_date="2019-01-20"
                     /db_xref="taxon:1390"
                     /geo_loc_name="India: West Bengal"
                     /host="Suaeda monoica"
                     /identified_by="Dr. Madhumita Roy"
                     /isolation_source="Endophyte"
                     /lat_lon="21.5799 N 88.3014 E"
                     /mol_type="genomic DNA"
                     /organism="Bacillus amyloliquefaciens"
                     /strain="SN_Endo51"
                     /submitter_seqid="sequence39"
     region          1..18628
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX) and not
                     alpha_am_amid)"
                     /tool="antismash"
     cand_cluster    1..18628
                     /SMILES="NC(C(C)CC)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX) and not alpha_am_amid)"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..18628
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[790:12242](-)"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(791..12242)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     CDS             <5..785
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=3
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684984.1"
                     /locus_tag="K8B35_RS20510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="transposase"
                     /protein_id="WP_224988963.1"
                     /transl_table=11
                     /translation="HTNSRDAIHVLDGLLHHETDLNIVEYYTDTAGYTDQIFGLTHLLG
                     FKFAPRIRDLSDSKLFTIDKASEYPKLEVILRGQINTKVIKENYEDVLRLAHSIREGTV
                     SASLIMGKLGSYSRQNSLATALREMGRIEKTIFILNYISDESLRRKIQKGLNKGEAMNG
                     LARAIFFGKQGELRERTIQHQLQRASALNIIINAISIWNTLHLTKAVEYQKRSGSFNEE
                     LLHHMSPLGWEHINLLGEYHFNSEKMVSLDSLRPLKLS"
     gene            complement(791..4570)
                     /locus_tag="K8B35_RS20515"
     CDS             complement(791..4570)
                     /NRPS_PKS="Domain: NRPS-COM_Nterm (0-29). E-value: 4.7e-17.
                     Score: 52.9. Matches aSDomain:
                     nrpspksdomains_K8B35_RS20515_NRPS-COM_Nterm.1"
                     /NRPS_PKS="Domain: Condensation_DCL (7-308). E-value:
                     2.5e-114. Score: 373.4. Matches aSDomain:
                     nrpspksdomains_K8B35_RS20515_Condensation_DCL.1"
                     /NRPS_PKS="Domain: AMP-binding (473-866). E-value:
                     4.6e-106. Score: 346.8. Matches aSDomain:
                     nrpspksdomains_K8B35_RS20515_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (970-1037). E-value: 9.7e-22. Score:
                     69.0. Matches aSDomain: nrpspksdomains_K8B35_RS20515_PCP.1"
                     /NRPS_PKS="Domain: Thioesterase (1057-1173). E-value:
                     1.6e-31. Score: 102.5. Matches aSDomain:
                     nrpspksdomains_K8B35_RS20515_Thioesterase.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thioesterase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127: condensation domain-containing protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010334452.1"
                     /locus_tag="K8B35_RS20515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="non-ribosomal peptide synthetase"
                     /protein_id="WP_224988964.1"
                     /sec_met_domain="Condensation (E-value: 1e-88, bitscore:
                     286.3, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 1.3e-113, bitscore:
                     368.7, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 6.5e-15, bitscore:
                     44.6, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Thioesterase (E-value: 6.7e-25, bitscore:
                     77.6, seeds: 16, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKTKNIQNIYPLSRMQEGMLFHSFLQKEGAAYIEQSVFTIKGRL
                     RPELFEQSVQSVISRHDIFRTVFLPHVAQLNGPRQVVLREREFRLHREDLTHLDKAEQS
                     VYLQRFKERDRLKGFDLQKDMLMRVSLFKTADEEYVCVWSHHHILMDGWCLGIVLQEFM
                     HMYRAIESGSPVTLAPAKPYSTYITWLTDQDKDAASEYWKGYLAGCETPSGLPKISARP
                     QEKGYRKKELLFSLDQNLTDRLKTIAKEEGATLAVLMQTVWGLMLQRYNRTDDAVFGAV
                     VSGRPSVIDGVESMIGLFINTVPVRIKTGDESFRELLGRCQKEMLDSEAFSYHPLADIQ
                     SQTELKQDLIDHIIVFENYPVQQQMKDAEKESDAPFRIGNVNVSEQSGYDFNLIIAPGD
                     ELLIKFSYNANVYDEVWIESVKGHLEEALRGAAFNPDVPADRLPMLGQKEKSRIIGEFN
                     DTKTTYERDESIISLFSRQVKKTPDHQALHAGGLTMTYRELDERSTAFARTLLENGLAP
                     KGIAGILAERSPEFIIAVLAVLKAGGTYLPLDAELPTDRIADMLTESGAQLLTVQKGIE
                     TDFDFSHIISIPAAAEKQTADAGKLNTDTAPDDLAYIMYTSGSTGKPKGVMISNRNVVS
                     LVSNSNYTSAGMTDRLILTGSIGFDAVTFEIFGALLNGACLHVVDRSTMLAPERFGNYL
                     SSNRITILFLTTALFNQFAQTDPEMFSGLYTLYVGGEALSPALINKVRHRCPNLSLYNI
                     YGPTENTTFSTFYEIRYDFSQPIPIGKPISNSTAYIIDKNGGLAPIGVPGELCVGGDGV
                     AKGYLNRPDLTSEAFVSHPVHPEEKIYKTGDLAHWLPDGSIGYISRIDRQFKIRGKRIE
                     PAEIEARLTEIDGIREAAVIVSDEGQEAILCAYYTGAHVEERAIRSLLARSLPDYMIPQ
                     YVMKLDRMPLTANGKVDRRGLPAPERKKTSSKAVPPRNWVERELIDIWTPILGCGELGI
                     QDDFFELGGHSLKALQVIHQLKTRQQMDVPIEMIFEYPTIEQLAEKLYSNTLSEAAEQH
                     ISRLNQPKGRNLFCFPPISGFGIFFKDLAAALNGRAAVYGFNFIEEDSRMEQYIDKMLE
                     IQPEGPYILFGYSAGGNTAFEAAKAMEKRGLEISDVIIADAYRKLDALPPQPTNATADN
                     VPEAVREAVIKKTERYQTYWAELINDGQIAANLHFIEAGIKEEHSDKTEPMKWEGATTG
                     LYQEYQGGGAHKGVQSGKCGFTTLSPFPRLFPQF"
     aSDomain        complement(1052..1399)
                     /ASF="active site serine present: True"
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_K8B35_RS20515_Thioesterase.1"
                     /evalue="1.60E-31"
                     /label="K8B35_RS20515_Thioesterase.1"
                     /locus_tag="K8B35_RS20515"
                     /protein_end="1173"
                     /protein_start="1057"
                     /score="102.5"
                     /tool="antismash"
                     /translation="RNLFCFPPISGFGIFFKDLAAALNGRAAVYGFNFIEEDSRMEQYI
                     DKMLEIQPEGPYILFGYSAGGNTAFEAAKAMEKRGLEISDVIIADAYRKLDALPPQPTN
                     ATADNVPEAVRE"
     aSModule        complement(1052..4549)
                     /complete
                     /domains="nrpspksdomains_K8B35_RS20515_Condensation_DCL.1"
                     /domains="nrpspksdomains_K8B35_RS20515_AMP-binding.1"
                     /domains="nrpspksdomains_K8B35_RS20515_PCP.1"
                     /domains="nrpspksdomains_K8B35_RS20515_Thioesterase.1"
                     /final_module
                     /locus_tags="K8B35_RS20515"
                     /monomer_pairings="Ile -> Ile"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(1175..1246)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_K8B35_RS20515_0010"
                     /evalue="4.80E-11"
                     /label="NRPS-te1"
                     /locus_tag="K8B35_RS20515"
                     /protein_end="1132"
                     /protein_start="1108"
                     /score="35.0"
                     /tool="antismash"
                     /translation="QPEGPYILFGYSAGGNTAFEAAKA"
     aSDomain        complement(1460..1660)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_K8B35_RS20515_PCP.1"
                     /evalue="9.70E-22"
                     /label="K8B35_RS20515_PCP.1"
                     /locus_tag="K8B35_RS20515"
                     /protein_end="1037"
                     /protein_start="970"
                     /score="69.0"
                     /tool="antismash"
                     /translation="ERELIDIWTPILGCGELGIQDDFFELGGHSLKALQVIHQLKTRQQ
                     MDVPIEMIFEYPTIEQLAEKLY"
     CDS_motif       complement(1943..2008)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_K8B35_RS20515_0009"
                     /evalue="2.10E-09"
                     /label="NRPS-A_a8"
                     /locus_tag="K8B35_RS20515"
                     /protein_end="876"
                     /protein_start="854"
                     /score="29.5"
                     /tool="antismash"
                     /translation="YISRIDRQFKIRGKRIEPAEIE"
     aSDomain        complement(1973..3151)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_K8B35_RS20515_AMP-binding.1"
                     /evalue="4.60E-106"
                     /label="K8B35_RS20515_AMP-binding.1"
                     /locus_tag="K8B35_RS20515"
                     /protein_end="866"
                     /protein_start="473"
                     /score="346.8"
                     /specificity="substrate consensus: Ile"
                     /tool="antismash"
                     /translation="FSRQVKKTPDHQALHAGGLTMTYRELDERSTAFARTLLENGLAPK
                     GIAGILAERSPEFIIAVLAVLKAGGTYLPLDAELPTDRIADMLTESGAQLLTVQKGIET
                     DFDFSHIISIPAAAEKQTADAGKLNTDTAPDDLAYIMYTSGSTGKPKGVMISNRNVVSL
                     VSNSNYTSAGMTDRLILTGSIGFDAVTFEIFGALLNGACLHVVDRSTMLAPERFGNYLS
                     SNRITILFLTTALFNQFAQTDPEMFSGLYTLYVGGEALSPALINKVRHRCPNLSLYNIY
                     GPTENTTFSTFYEIRYDFSQPIPIGKPISNSTAYIIDKNGGLAPIGVPGELCVGGDGVA
                     KGYLNRPDLTSEAFVSHPVHPEEKIYKTGDLAHWLPDGSIGYISRIDRQFKIR"
     CDS_motif       complement(2090..2179)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_K8B35_RS20515_0008"
                     /evalue="1.40E-17"
                     /label="NRPS-A_a6"
                     /locus_tag="K8B35_RS20515"
                     /protein_end="827"
                     /protein_start="797"
                     /score="55.8"
                     /tool="antismash"
                     /translation="PIGVPGELCVGGDGVAKGYLNRPDLTSEAF"
     CDS_motif       complement(2684..2740)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_K8B35_RS20515_0007"
                     /evalue="3.30E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="K8B35_RS20515"
                     /protein_end="629"
                     /protein_start="610"
                     /score="31.8"
                     /tool="antismash"
                     /translation="AYIMYTSGSTGKPKGVMIS"
     CDS_motif       complement(2924..2965)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_K8B35_RS20515_0006"
                     /evalue="3.10E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="K8B35_RS20515"
                     /protein_end="549"
                     /protein_start="535"
                     /score="17.2"
                     /tool="antismash"
                     /translation="LAVLKAGGTYLPLD"
     CDS_motif       complement(3491..3607)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_K8B35_RS20515_0005"
                     /evalue="1.30E-19"
                     /label="C67_DCL_14fromHMM"
                     /locus_tag="K8B35_RS20515"
                     /protein_end="360"
                     /protein_start="321"
                     /score="62.7"
                     /tool="antismash"
                     /translation="QKEMLDSEAFSYHPLADIQSQTELKQDLIDHIIVFENYP"
     aSDomain        complement(3647..4549)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_K8B35_RS20515_Condensation_DCL.1
                     "
                     /domain_subtypes="Condensation_DCL"
                     /evalue="2.50E-114"
                     /label="K8B35_RS20515_Condensation_DCL.1"
                     /locus_tag="K8B35_RS20515"
                     /protein_end="308"
                     /protein_start="7"
                     /score="373.4"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHILMDG"
                     /tool="antismash"
                     /translation="QNIYPLSRMQEGMLFHSFLQKEGAAYIEQSVFTIKGRLRPELFEQ
                     SVQSVISRHDIFRTVFLPHVAQLNGPRQVVLREREFRLHREDLTHLDKAEQSVYLQRFK
                     ERDRLKGFDLQKDMLMRVSLFKTADEEYVCVWSHHHILMDGWCLGIVLQEFMHMYRAIE
                     SGSPVTLAPAKPYSTYITWLTDQDKDAASEYWKGYLAGCETPSGLPKISARPQEKGYRK
                     KELLFSLDQNLTDRLKTIAKEEGATLAVLMQTVWGLMLQRYNRTDDAVFGAVVSGRPSV
                     IDGVESMIGLFINTVPVRIK"
     CDS_motif       complement(3653..3748)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_K8B35_RS20515_0004"
                     /evalue="5.90E-19"
                     /label="C5_DCL_263-294"
                     /locus_tag="K8B35_RS20515"
                     /protein_end="306"
                     /protein_start="274"
                     /score="60.5"
                     /tool="antismash"
                     /translation="DAVFGAVVSGRPSVIDGVESMIGLFINTVPVR"
     CDS_motif       complement(4073..4138)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_K8B35_RS20515_0003"
                     /evalue="3.90E-11"
                     /label="C3_DCL_135-156"
                     /locus_tag="K8B35_RS20515"
                     /protein_end="166"
                     /protein_start="144"
                     /score="35.3"
                     /tool="antismash"
                     /translation="HHHILMDGWCLGIVLQEFMHMY"
     CDS_motif       complement(4364..4480)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_K8B35_RS20515_0002"
                     /evalue="8.90E-17"
                     /label="C2_DCL_024-062"
                     /locus_tag="K8B35_RS20515"
                     /protein_end="69"
                     /protein_start="30"
                     /score="53.4"
                     /tool="antismash"
                     /translation="AAYIEQSVFTIKGRLRPELFEQSVQSVISRHDIFRTVFL"
     aSDomain        complement(4484..4570)
                     /aSDomain="NRPS-COM_Nterm"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_K8B35_RS20515_NRPS-COM_Nterm.1"
                     /evalue="4.70E-17"
                     /label="K8B35_RS20515_NRPS-COM_Nterm.1"
                     /locus_tag="K8B35_RS20515"
                     /protein_end="29"
                     /protein_start="0"
                     /score="52.9"
                     /tool="antismash"
                     /translation="MDKTKNIQNIYPLSRMQEGMLFHSFLQKE"
     CDS_motif       complement(4499..4540)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_K8B35_RS20515_0001"
                     /evalue="4.00E-05"
                     /label="C1_DCL_004-017"
                     /locus_tag="K8B35_RS20515"
                     /protein_end="24"
                     /protein_start="10"
                     /score="15.5"
                     /tool="antismash"
                     /translation="YPLSRMQEGMLFHS"
     gene            complement(4589..12242)
                     /locus_tag="K8B35_RS20520"
                     /pseudo=""
     CDS             complement(4589..12242)
                     /NRPS_PKS="Domain: Condensation_Starter (3-299). E-value:
                     2.1e-86. Score: 281.9. Matches aSDomain:
                     nrpspksdomains_K8B35_RS20520_Condensation_Starter.1"
                     /NRPS_PKS="Domain: AMP-binding (463-868). E-value:
                     2.7e-108. Score: 354.1. Matches aSDomain:
                     nrpspksdomains_K8B35_RS20520_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127: condensation domain-containing protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013352476.1"
                     /locus_tag="K8B35_RS20520"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="amino acid adenylation domain-containing protein"
                     /pseudo=""
                     /sec_met_domain="Condensation (E-value: 4.2e-69, bitscore:
                     221.9, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 1.4e-119, bitscore:
                     388.4, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKNTVYSLTHAQRRVWFTELLEPGTSICNLAACVKFRGDIDFDVL
                     RHALDFSISQNDSLRFQLTEGDGSEPQLYLAGHRPISLETVDFTHTDQAERDAWIDTQT
                     RVPFKLFHSPLYHFTLLVMSDEEVWLYSKFHHIIMDGISLNLLGNQLIDIYQKIMRGED
                     LTEHHRPSYLSYMEKEQQYLQSSRFQKDRSFWTETYRTVPEHLSLAERTSHLRQSTAAS
                     RDTITLSHSLEQSIRRFCKENNISIISLFMASLYICISRLTAKKDIAIGTYYGNRGSRL
                     EKDMLGMFVSTLPIRMTADPDAEFLSFVRSVGKEQLSVMRHQKYPYNLFVNELRQTHHD
                     LQNIIGISMQYQPLAWRQAEGFDYETAMFFSGHTANELSILIKERTDTGLIELNFDYQS
                     ALFTKTSIKRIQTHLLTIVENAVRNPNQLIRHIDMADENEKKRVLTAFNRTEAVEPPAP
                     TLHGLFTRRAALSPHRPALRFPGGMLTYAELDQYTDRLAVRLRQKGVRKESMVGVLAER
                     SPEMVVSVLAVLKAGGAYVPLDPEYPEDRLRYMLDDSGACLLLAQPGLSLSGFSGETLE
                     VSLSSLTSETETGDVSEEADADSLAYIIYTSGSTGTPKGVAVEHRQAAAFLSGMQGQFP
                     LTEEDIIVLKSSFSFDASIWQLFWWTMSGASVYLLPAGWEKDPVRMIEAFSSEKVTTAH
                     FIPAMVNSFLDALETEPAETRTRLGRTLTRVFAGGEALSPLTAARFADLLPETVLIHGY
                     GPTEATVDAAFYVCDRKRDSGRTRLPIGKPVPGARLYVLDSGGTIQPAGVAGELYIAGT
                     GVARGYLNRPELTEERFLDDPFYPGERMYQTGDIARWTEDGLVEWLGRSDGQVKVRGYR
                     IEPGEIEAAIRRIDGIREAAVTARTEHGETALYAYIEGRESDDVRAELAARFRPT"
     CDS_motif       complement(9609..9674)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_K8B35_RS20520_0010"
                     /evalue="1.30E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="K8B35_RS20520"
                     /protein_end="878"
                     /protein_start="856"
                     /score="36.4"
                     /tool="antismash"
                     /translation="WLGRSDGQVKVRGYRIEPGEIE"
     aSDomain        complement(9639..10853)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_K8B35_RS20520_AMP-binding.1"
                     /evalue="2.70E-108"
                     /label="K8B35_RS20520_AMP-binding.1"
                     /locus_tag="K8B35_RS20520"
                     /protein_end="868"
                     /protein_start="463"
                     /score="354.1"
                     /specificity="substrate consensus: Glu"
                     /tool="antismash"
                     /translation="FTRRAALSPHRPALRFPGGMLTYAELDQYTDRLAVRLRQKGVRKE
                     SMVGVLAERSPEMVVSVLAVLKAGGAYVPLDPEYPEDRLRYMLDDSGACLLLAQPGLSL
                     SGFSGETLEVSLSSLTSETETGDVSEEADADSLAYIIYTSGSTGTPKGVAVEHRQAAAF
                     LSGMQGQFPLTEEDIIVLKSSFSFDASIWQLFWWTMSGASVYLLPAGWEKDPVRMIEAF
                     SSEKVTTAHFIPAMVNSFLDALETEPAETRTRLGRTLTRVFAGGEALSPLTAARFADLL
                     PETVLIHGYGPTEATVDAAFYVCDRKRDSGRTRLPIGKPVPGARLYVLDSGGTIQPAGV
                     AGELYIAGTGVARGYLNRPELTEERFLDDPFYPGERMYQTGDIARWTEDGLVEWLGRSD
                     GQVKVR"
     aSModule        complement(9639..12233)
                     /domains="nrpspksdomains_K8B35_RS20520_Condensation_Starter
                     .1"
                     /domains="nrpspksdomains_K8B35_RS20520_AMP-binding.1"
                     /incomplete
                     /locus_tags="K8B35_RS20520"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(9756..9845)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_K8B35_RS20520_0009"
                     /evalue="3.60E-18"
                     /label="NRPS-A_a6"
                     /locus_tag="K8B35_RS20520"
                     /protein_end="829"
                     /protein_start="799"
                     /score="57.6"
                     /tool="antismash"
                     /translation="PAGVAGELYIAGTGVARGYLNRPELTEERF"
     CDS_motif       complement(9831..9872)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_K8B35_RS20520_0008"
                     /evalue="4.20E+00"
                     /label="NRPS-A_a3"
                     /locus_tag="K8B35_RS20520"
                     /protein_end="804"
                     /protein_start="790"
                     /score="1.2"
                     /tool="antismash"
                     /translation="VLDSGGTIQPAGVA"
     CDS_motif       complement(10383..10442)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_K8B35_RS20520_0007"
                     /evalue="4.80E-11"
                     /label="NRPS-A_a3"
                     /locus_tag="K8B35_RS20520"
                     /protein_end="620"
                     /protein_start="600"
                     /score="34.4"
                     /tool="antismash"
                     /translation="AYIIYTSGSTGTPKGVAVEH"
     CDS_motif       complement(10626..10667)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_K8B35_RS20520_0006"
                     /evalue="1.70E-06"
                     /label="NRPS-A_a2"
                     /locus_tag="K8B35_RS20520"
                     /protein_end="539"
                     /protein_start="525"
                     /score="20.9"
                     /tool="antismash"
                     /translation="LAVLKAGGAYVPLD"
     CDS_motif       complement(11190..11303)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_K8B35_RS20520_0005"
                     /evalue="9.50E-08"
                     /label="C67_starter_14fromHMM"
                     /locus_tag="K8B35_RS20520"
                     /protein_end="351"
                     /protein_start="313"
                     /score="24.6"
                     /tool="antismash"
                     /translation="KEQLSVMRHQKYPYNLFVNELRQTHHDLQNIIGISMQY"
     aSDomain        complement(11346..12233)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_K8B35_RS20520_Condensation_Start
                     er.1"
                     /domain_subtypes="Condensation_Starter"
                     /evalue="2.10E-86"
                     /label="K8B35_RS20520_Condensation_Starter.1"
                     /locus_tag="K8B35_RS20520"
                     /protein_end="299"
                     /protein_start="3"
                     /score="281.9"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHIIMDG"
                     /tool="antismash"
                     /translation="TVYSLTHAQRRVWFTELLEPGTSICNLAACVKFRGDIDFDVLRHA
                     LDFSISQNDSLRFQLTEGDGSEPQLYLAGHRPISLETVDFTHTDQAERDAWIDTQTRVP
                     FKLFHSPLYHFTLLVMSDEEVWLYSKFHHIIMDGISLNLLGNQLIDIYQKIMRGEDLTE
                     HHRPSYLSYMEKEQQYLQSSRFQKDRSFWTETYRTVPEHLSLAERTSHLRQSTAASRDT
                     ITLSHSLEQSIRRFCKENNISIISLFMASLYICISRLTAKKDIAIGTYYGNRGSRLEKD
                     MLGMFVSTLPIRMTA"
     CDS_motif       complement(11355..11444)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_K8B35_RS20520_0004"
                     /evalue="9.60E-09"
                     /label="C5_starter_265-294"
                     /locus_tag="K8B35_RS20520"
                     /protein_end="296"
                     /protein_start="266"
                     /score="27.7"
                     /tool="antismash"
                     /translation="DIAIGTYYGNRGSRLEKDMLGMFVSTLPIR"
     CDS_motif       complement(11778..11843)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_K8B35_RS20520_0003"
                     /evalue="5.70E-08"
                     /label="C3_starter_134-155"
                     /locus_tag="K8B35_RS20520"
                     /protein_end="155"
                     /protein_start="133"
                     /score="25.6"
                     /tool="antismash"
                     /translation="FHHIIMDGISLNLLGNQLIDIY"
     CDS_motif       complement(12048..12167)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_K8B35_RS20520_0002"
                     /evalue="1.90E-11"
                     /label="C2_starter_024-063"
                     /locus_tag="K8B35_RS20520"
                     /protein_end="65"
                     /protein_start="25"
                     /score="36.6"
                     /tool="antismash"
                     /translation="SICNLAACVKFRGDIDFDVLRHALDFSISQNDSLRFQLTE"
     CDS_motif       complement(12189..12227)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_K8B35_RS20520_0001"
                     /evalue="5.60E-03"
                     /label="C1_starter_004-017"
                     /locus_tag="K8B35_RS20520"
                     /protein_end="18"
                     /protein_start="5"
                     /score="9.7"
                     /tool="antismash"
                     /translation="YSLTHAQRRVWFT"
     misc_feature    complement(12365..12374)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 17.22"
                     /tool="antismash"
     misc_feature    complement(12559..12572)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 20.79"
                     /tool="antismash"
     misc_feature    complement(12560..12573)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 20.09"
                     /tool="antismash"
     misc_feature    complement(12561..12574)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 21.75"
                     /tool="antismash"
     gene            complement(12723..14198)
                     /gene="dacB"
                     /locus_tag="K8B35_RS20525"
     CDS             complement(12723..14198)
                     /EC_number="3.4.16.4"
                     /GO_function="GO:0004175 - endopeptidase activity [Evidence
                     IEA]"
                     /GO_function="GO:0009002 - serine-type D-Ala-D-Ala
                     carboxypeptidase activity [Evidence IEA]"
                     /GO_process="GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="dacB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015388145.1"
                     /locus_tag="K8B35_RS20525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="D-alanyl-D-alanine
                     carboxypeptidase/D-alanyl-D-alanine-endopeptidase"
                     /protein_id="WP_095060664.1"
                     /transl_table=11
                     /translation="MKTYVKRLSAVILLLIIAAVPYIDDAAKAADQKNTLQKELEHILD
                     EEPALKGASAGVSVRSAKTGEVLFGSREDMRLRPASLMKLLTASAALSVLGEDYTFKTE
                     VRADGAVKGKQLRGNLYLRGKGDPTLLVSDFEKMAKQVKARGIHVIKGDLVGDDSWYDD
                     TRYSVDLPWSDEGQYYGAQVSALTASPNEDYDTGTVIAEISPAKQPGKKPRISISPHTD
                     VVRVKNEVKTVASDEKKELTVEREHGGNVITIKGTIPVGSAQAREWAAVWDPSSYALDL
                     WKQALTKQGITVKGKIRTGRMPHRTQLVTSRTSMPLSELLIPFMKLSNNGHAEILIKEM
                     GKVKKGEGSWEKGLDVMKSELKSFGLNPDELIARDGSGVSHINGVSAGQIGELLYAVQK
                     EKWYPAFLRSLPVAGASDRMTGGTLRNRLKGTPAEGKIKAKTGSLTSVSSIAGYADTKT
                     GDTLIFSVLQNGLLDEDDGKDIEDKIAVVLANQ"
     gene            complement(14217..15185)
                     /locus_tag="K8B35_RS20530"
     CDS             complement(14217..15185)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003153855.1"
                     /locus_tag="K8B35_RS20530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="aldose 1-epimerase"
                     /protein_id="WP_159354244.1"
                     /transl_table=11
                     /translation="MTIEHTTYLGVSAIKAETDQAECIIVPEWGSNVISLRDKRTGMRL
                     LREPETAEQFRAKPMLYGIPVLFPPNRITDGTFRFDGRAYQFEINEEDKHNHIHGFLHN
                     QHWKVAAAKEEGDGMTVETEIDLSKIPRVHKQFPHDVIVRMTYTLKDNVFTQRALITNK
                     GTEAFPWGLGYHSTFVFNEERSRLFLTADRMWELNERFVPTGRLLDVPDKEAFHHGISL
                     KNKQFDDVFLSSGRNGGNNEAVIYHPDEKLSVLYQADTSFKHWVVYNGDGKQGFVSLEP
                     YTSVTDAFNLNQPASLTGLQILKPGEEAAASSRITILHDEE"
     misc_feature    complement(15255..15264)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 18.31"
                     /tool="antismash"
     gene            complement(15300..16688)
                     /locus_tag="K8B35_RS20535"
     CDS             complement(15300..16688)
                     /codon_start=1
                     /function="Na+-driven multidrug efflux pump"
                     /gene_functions="transport (smcogs) SMCOG1086: MATE efflux
                     family protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003153854.1"
                     /locus_tag="K8B35_RS20535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MATE family efflux transporter"
                     /protein_id="WP_014418076.1"
                     /transl_table=11
                     /translation="MEVQDHLETAEGRGQSVWRSMSLFLVPLLLSNVLQSVGQLVGMVF
                     VGRWLGVDALAAVSSFFPLFFLLISFTIGIGSGSSILIGQAYGAKNEERMKAIVGTTLT
                     FTFMLGVVLAVVGSVFTLDILRLMGTPENVIDVSVRYARILFCAMPLMFLYFAYTTFLR
                     GTGDSKTPFYTLIVSTVINIGLLPLLILGLFGLPKFGIYGSAYATVISNIVTFIVLMVY
                     LRKRKHPLAFDRTALRSLKMDKKLLALLLRLGIPSSINMILVSLSEIAVISFVNHYGSN
                     ATAAYGVVNQVASYVQMPAVSLGIAVSIFAAQSIGANQFGRLKQVIKVGIGLNYLIGGV
                     LILLIYTFSRQILALFLTDQDTLHIARNLIMITLWSYLIFGHAQIVSATMRASGTVLWP
                     TIISIFAIWGIEVPVAFILSHYTNLGILGIWVGYPAAFVVSLLLQYGYYRFVWKKKQIT
                     RLIQ"
     misc_feature    16759..16774
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 22.41"
                     /tool="antismash"
     gene            16917..17459
                     /locus_tag="K8B35_RS20540"
     CDS             16917..17459
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389720.2"
                     /locus_tag="K8B35_RS20540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="IseA DL-endopeptidase inhibitor family protein"
                     /protein_id="WP_053573325.1"
                     /transl_table=11
                     /translation="MKKWLLFLTTITLILSLGTAATAKNAPNDLTQKQALQLALSAREH
                     FWNTMSGGALKTNENCTSEPFEYQNLQYVFMCKDLGTKAKAVKYLTPAFTKQAIDKGLK
                     DYHFTVKDGKLAVPVGDGDNLLNWKKAKMTLLSKKGSAQTYRFTVPTLDGSPSAKRDVT
                     FVKENNVWKVNQFDAVI"
     tRNA            complement(17604..17676)
                     /anticodon=(pos:complement(17641..17643),aa:Arg,seq:cct)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="K8B35_RS20545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /product="tRNA-Arg"
     gene            complement(17604..17676)
                     /locus_tag="K8B35_RS20545"
     gene            complement(17719..18264)
                     /locus_tag="K8B35_RS20550"
     CDS             complement(17719..18264)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1077: phage integrase
                     family protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389721.2"
                     /locus_tag="K8B35_RS20550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="site-specific integrase"
                     /protein_id="WP_003153850.1"
                     /transl_table=11
                     /translation="MHIVQPIRSLEKIQEVKQYLMKKSDRDYFLFIFGMNSALRISDVL
                     PLRVRDVRNKDHVWATESKTRKKRKILILESLKADIYAYTKDMKEDDYLFKSKRTNKPI
                     SRIQAYRILKEAAAACGLEEIGTHTLRKTFGYHFYQRTKDIAELQRILNHSSPSITMRY
                     IGIDEDTTRAAYKVFGGL"
ORIGIN
        1 ttcatactaa ttcaagggat gcgattcatg ttttggatgg tttgttacac catgagacgg
       61 atctaaatat agtagagtat tatacagaca cggctggtta cacagaccaa atattcggac
      121 tgacccattt attaggattt aaatttgctc caagaatacg agatttatca gactcgaaat
      181 tatttacaat agataaggca agtgagtatc caaaattaga agtcatttta cgtggacaaa
      241 taaatacaaa ggtcattaaa gagaattatg aggatgtttt gcgattagct cattctataa
      301 gggaaggaac agtttcagca tcccttatta tggggaaatt aggttcttat tcaagacaaa
      361 acagcttggc tacagcctta cgtgagatgg gccgaataga aaaaacgatc tttattttga
      421 attatatttc ggatgaatca ttaagaagaa aaatacaaaa aggattgaat aaaggagaag
      481 ccatgaatgg actggcaaga gccattttct tcggaaaaca aggagagctt agggaacgaa
      541 ccatacagca tcaattgcaa agagccagtg ccttaaacat cattatcaat gccatcagta
      601 tctggaatac tttacatcta acaaaggcag ttgaatatca aaaacggtca ggtagtttta
      661 atgaagaatt attgcaccat atgtcacctc taggttggga acatattaat ttacttggag
      721 aataccattt taattcggag aaaatggtct cgttagattc tttaagaccc ttgaaacttt
      781 cttaacgttg ttaaaactgg gggaatagtc ggggaaatgg gcttagcgtt gtaaatccgc
      841 attttcctga ctgtacccct ttatgggcgc ccccgccttg atattcctga tagagtcccg
      901 ttgtggcgcc ttcccatttc atcggctcgg tcttatcact gtgttcttcc tttatgccgg
      961 cctcgataaa atggaggttg gccgcgattt ggccgtcatt tatcagttcc gcccagtacg
     1021 tttgatagcg ctctgtcttt ttgatgactg cttctctgac ggcttccggg acgttgtcgg
     1081 ctgttgcgtt tgttggctgc ggcggcagtg cgtcaagctt tctgtacgcg tctgcgataa
     1141 tgacgtcact gatttctaaa ccgcgctttt ccatcgcttt tgccgcctcg aatgccgtat
     1201 tgccgcctgc cgaatatccg aagaggatat aagggccttc cggctggatt tccagcattt
     1261 tatcaatgta ttgttccatt ctgctgtctt cttcaataaa gttaaaaccg tacacagcag
     1321 cccgtccgtt taatgccgcc gcaagatctt taaagaaaat gccgaaacct gagataggcg
     1381 gaaaacagaa aagattgcgg cctttcggct ggttcagtct gctgatatgc tgctctgcag
     1441 cttctgacag tgtgtttgaa tacagctttt cagccaattg ttcaattgtc ggatattcaa
     1501 atatcatttc aatcggcaca tccatctgct gcctggtctt cagctgatga atcacttgca
     1561 atgctttcaa tgaatggccg cccagctcaa agaagtcatc ctgtatgccc agctccccgc
     1621 agccgaggat cggcgtccag atgtcgatca gctcacgctc tacccagttt cgtggcggaa
     1681 cggcttttga tgacgttttt ttccgttctg gcgcaggcag cccgcggcgg tccactttgc
     1741 cgtttgcggt aagcggcata cggtcaagct tcatcacata ctgaggaatc atatagtcgg
     1801 gaagcgacct ggccaacagg gatcgaatgg ctctttcttc aacatgcgcg cccgtataat
     1861 acgcacaaag gattgcttct tgtccttcgt ctgacacgat gactgccgct tccctgattc
     1921 catcaatttc agtcaagcgc gcttcgattt cggccggctc aatccgcttc ccgcgaatct
     1981 tgaattggcg gtcgatacgg ctgatgtatc cgatgcttcc atcaggcagc cagtgtgcca
     2041 aatcgcctgt tttgtagatc ttttcttcag gatgaaccgg gtggctgaca aatgcttcac
     2101 ttgttaagtc aggcctgttt aaatagcctt tggcaacccc gtcaccgccg acacaaagct
     2161 caccgggcac gccgatcggc gcaagtccgc catttttatc aatgatatac gcggttgaat
     2221 tgctgatcgg ttttccgatt gggattggct gagaaaaatc gtacctgatt tcgtaaaagg
     2281 tagaaaatgt cgtattttct gtcggtccgt atatgttata aaggctgaga ttcggacagc
     2341 ggtgtctgac cttattgatg agcgccgggg acaatgcttc tccgccgaca tataaggtgt
     2401 acaatccgga aaacatctcc ggatctgtct gggcaaactg gttaaagagc gccgtcgtca
     2461 aaaacaaaat cgtaatccgg ttggaagaaa gataattgcc gaacctctca ggggcaagca
     2521 ttgtcgagcg gtcaaccaca tgaagacagg ccccgttcaa aagcgctccg aagatttcaa
     2581 acgtcactgc gtcgaaaccg atggaccctg tcagaatgag acggtccgtc atgccggccg
     2641 acgtgtaatt gctgtttgac acgagcgata cgacgtttcg gttggaaatc atcacgccct
     2701 tcggttttcc tgttgaaccg gatgtataca taatataggc aaggtcatca ggtgctgtat
     2761 cggtattcag ttttcccgca tcagcggttt gtttctctgc ggcagccggg atagagatga
     2821 tgtgagaaaa gtcaaagtca gtctcaatcc ctttttgcac cgttaacagc tgtgctccgc
     2881 tctcagtgag catatcggcg atcctgtcgg ttggcagttc tgcatcaaga ggaaggtacg
     2941 tccctcccgc tttcaataca gcgagaacag cgatgataaa ttccggtgag cgttcggcca
     3001 gaatcccggc aattcccttt ggcgccaaac cgttttccag cagggtgcgg gcgaatgcag
     3061 ttgaccgttc atcgagctcc cggtacgtca tcgtcagccc gccggcgtga agcgcctgat
     3121 ggtccggggt tttcttcacc tgtcggctga ataggctgat gatgctttcg tctctttcat
     3181 aagttgtttt cgtgtcatta aattcgccga ttattcttga tttttccttt tgtccgagca
     3241 tcggaagccg atcagcggga acatcgggat tgaaggcggc gccgcgcaga gcttcttcca
     3301 agtgtccttt tacgctctct atccatactt cgtcataaac gttcgcattg tagctgaatt
     3361 tgatgagcag ctcatcgccg ggcgctatga tgaggttaaa atcgtagccc gattgttccg
     3421 acacgttgac attcccgatc cggaacggtg catccgattc cttttccgcg tctttcatct
     3481 gctgctgaac cggataattt tcaaacacga tgatatggtc gattaaatcc tgtttcagct
     3541 cagtctgaga ttggatgtca gcaagcggat ggtagctgaa cgcctctgaa tcaagcattt
     3601 ctttctggca gcggcccagc agttctctaa agctttcatc acccgtttta atgcgtaccg
     3661 gcacggtatt gataaacagc ccgatcatgc tttccacgcc gtcaatgacg gaaggccgcc
     3721 ctgatacgac ggcgccgaat acggcatcgt ccgtccggtt gtagcgctgc agcatcaggc
     3781 cccatacagt ctgcataaga accgcgagcg tagcgccctc ttctttggcg atggttttca
     3841 gcctgtctgt cagattttga tctaaagaaa acagcagctc tttcttacgg tagccttttt
     3901 cctgaggacg ggccgatatt ttcgggagtc ctgagggtgt ctcgcagcct gctaaatatc
     3961 ctttccaata ctcagaagcc gcgtctttgt cctgatcagt cagccatgta atataagtgc
     4021 tgtaaggctt tgcgggcgcc agtgtgacgg gtgagcctga ttcaatcgcc cggtacatat
     4081 gcatgaattc ctgaaggacg atgccgaggc accagccgtc cataaggatg tgatggtggc
     4141 tccagacgca tacatattcc tcgtctgccg ttttaaacaa agaaacacgc atcagcatat
     4201 ccttttgcaa gtcaaagcct tttaagcggt cacgttcctt aaatcgctgt aaatagacgc
     4261 tctgttccgc tttgtccaaa tgtgtaagat cttcgcggtg cagccggaat tccctctcac
     4321 gcagcacaac ttggcggggg ccgttcagct gagcgacatg aggtaaaaaa accgttctga
     4381 aaatatcgtg gcggctgatg acagactgta cgctttgctc aaacaattcc ggacgaagcc
     4441 ggccttttat ggtgaagacg gattgctcga tatatgcagc cccctccttt tgcagaaagg
     4501 aatgaaaaag cattccttcc tgcattcggc tgaggggata aatgttttgg atatttttcg
     4561 ttttgtccat gtgttcctcc cgctcggttt agtggaagct gagtaagtcg gcaatgtcct
     4621 gcaatgcttc ctcagtcagc tcccgatcat caaagtcact gacggtcttc tccgtatcag
     4681 ttttgctgag gcagtgttcc gagcagcttt cggacagccg ttcgatcgta tcttgccgga
     4741 agcgctccgt ttcataggaa atgctgacgg tcatccggcc ttttgccgca atcgcgctga
     4801 tttcaagtga ctgctcccgt ttccatgtat ctgtcacatc atctccgcct cccaaaggag
     4861 aaaactgaaa cgcgtcaggc tgttccgttt ctgccggatt cccgccgggc gcatcgaatt
     4921 gtccgagata attaaagctg atctccggtg ctttcccgaa agtcatcccg gcaagctccg
     4981 gcggtgtcaa atatttgagg acgccgtatc cgttcccttt atccggaatg cgccgcaatg
     5041 tgtctttgac ggttttcaat gtgcgaattt catattcttc atgaggttca taaactccgc
     5101 tccggaaaag caccgggtaa atggaagtga accaccccac cgtcctgctg atgtccgcac
     5161 ctgcctgctc cgattggcgt ccgtgtcctt caagggcgat tttcaacgcg tgccgcggcg
     5221 accacttttg aacggcaagc acggcggaag ccaaaagcac atcttgcgta tccgtattgt
     5281 aggcgctgtg cacatctttc aacagggcgt ccgtttcact ttctgtcaga gtgaaggata
     5341 ccgtgttccg tttttttgca ggagtttgag ataaatctgc ctgctcgtaa ggaagacttt
     5401 ctgtttcata gtgttcaatc tcccgccaat actccgcctg ctgaagaagc tgtctgcttt
     5461 cggcataatc ggccagctgc tccgtatatg ttttgaatga catggttttc ggagggagtt
     5521 tgatttcctg cccagagaag gcctgctcat aaacagaagc caagtcttcc aataaaatcc
     5581 gccatgatat cccgtcgaca gcgagatgat ggaccgtcag aaacaagtaa tcttctgctt
     5641 cagaacggaa tagccccgcc tgtacaagcg gcccgttctc taaatccatg tttctctgaa
     5701 gctctgcgac gcggcgtttt acaaaacgtt ccttctcatg ctcatcgcct tccatttcta
     5761 atatggtcag gctgtaaagc tgctcatctg cgaggtcagc cggtctgttg aagaggagaa
     5821 gacctttctc ttcgtctttt ttgcagacaa ggcgcaagga atcatgatga acggtaatgg
     5881 cttttaacgt tttcctcagg gcctcttcat ctattgaatt tgttctcgtc agcatgacgg
     5941 actggttaaa atggtttgct tccttcatgt cttgtgtgaa gaaccatttg tggaccggcg
     6001 accacttcac ttctccttct gcaggagctt ggctgaccgg ctgccgctct gtacggacat
     6061 aaggcgccag ctctctaatt gtcggccggc tgaaaatatc ttttacggcg atttgttttc
     6121 ctgcctgatg taatcgggct gatacttgca gggctttgat ggaatcgccg cccagttcaa
     6181 aaaatgattg atccgcggca atgttttcag tcccgagcac ttcgctccaa atcgcggaaa
     6241 gctctttttc catgtcgctt tcaggctcgg taaatgcccg tccggtgtgc gcttttttcc
     6301 gcggctcagg aagcgcgcgg cggtcaagct tcccgttcgg tgtgacaggc agggcttcaa
     6361 gtgtttcaaa gaacgccggc accatataag cgggcatttc atttctgagc gcctgctgca
     6421 cggtttcact ttccgttcct tcttctgtca cgatataagc gcatagttcc gtttggcctg
     6481 ctgatgcggg cagagcggtg acggctgctt ctttgacacc ttttatgcct gttaaggcgg
     6541 attcaatttc tttcagttcc acccggtagc ctctgatttt gacttgctcg tccattcggc
     6601 cgatatattg cagcgtgccg tccggcagcc attttgccag gtcgcccgtg cggtacatgc
     6661 gccggttctt ccggaacggg tcttggacaa aggcttgagc cgtttgctta ggaagattgc
     6721 ggtaccctct tgcaaggccg gaacccgaaa tgcaaagttc tcccgttaca ccgatcggct
     6781 gcgggtgatc cccgtttaaa atataaacgt gtgaatgctc aatcggacgg ccgatcgtaa
     6841 tgttctcact ttgttctata tgtcttgccg ctgtagtggc gacgctgttt tccgtcggtc
     6901 cgtactcatt ggcaagctca gtgtgtggac aaactgataa actgcggctg ataacgtttt
     6961 ggtcgacggc ttctcccgct aatgtgacaa tccggagaga ctcggcatca cccggctcca
     7021 gtacgtcaag cagtgtgcga tacagcacgg gaacaatgat catgtgagtg atgcggtaag
     7081 atgcaagata gtgtttaata gcaagaatat ctcttgcttc atcttcggct aaaacggccg
     7141 ctttcgcacc ggaaaccagc ggtgtgaaca tacttgttac aaaaccgtca aatgaaaatg
     7201 aaaagagctg aagaatcgta tctttctcat tcagatcata aaatccgctc cgccattgaa
     7261 gggtttggct gacggaacga tgttcgacca taaccccttt cggcctgcct gtcgtcccgg
     7321 acgtgtaaat gagtaagcca aatcttccgg tgctgataat gactgaaccg gtgatgcgtc
     7381 ttgttcttgg atatcctcca gtgcgagcac ttcaccttta aaatgatcag gcacttgatc
     7441 tattgcgccg tgtacggtaa ggagaagcgc tgtgccgctg tctgagatga tatattgctt
     7501 gcgttcctcc ggatattcag gatctatcgg gacgtaggcg cccccggctt tcaaaacccc
     7561 gaagactgcc gcgacttgtt ccggtgatct tggtatcaca atgccgacgg cggcatccgg
     7621 tccgatctgc cgtttttgca gagctctggc gattttattc gaccattcat ctaattcttt
     7681 atatgtgatt aaagtttccc cgctgataag ggctgccgca tccggtgttt ttcgcgcctg
     7741 ggtgatgaac agttcatgaa ctgttttttc aggcagctgt tgatccgcca tgccgttaaa
     7801 gtccgaaaga atccggttcc gttccggagc agtcagcatg ctgatcgctt gtatagaagt
     7861 ttccggttca cggacaatgt gttcaagcat cgtcataaag tgggaagccc agcgctgcat
     7921 cgtttctttc cggaataatg acgccgcata ttcaaacaga aaatgaatct gtcccccgcc
     7981 ttcagaagcc tgcaaagtga catcaaattt ggaaaccgga cgggacacgt ccgcaggctg
     8041 aatatgcaaa ccgtccaaca gcagttcctc atgctccata ttctgaacga caagcatggc
     8101 gtcaaacagc ggattgcggc ttgtgtcccg ctgcacgccg agccgttcca caagctcttc
     8161 aaacgggtag tcctgatgct catacgcttc aagcgcggcc tggcggactt ccgccaaata
     8221 atcggtaaac cgtttgtctc ctttcggctc cgttctgatg gccagcgtgt tgacgaacat
     8281 gccgagaatc ggttcaaggt ctttgtgcgg acgcccggca atcggcgagc cgacgatgat
     8341 gtcttcctga ccgctcaatc tcgcgagtaa cgcattgtac gcggcgagaa gcaccatata
     8401 caaagtggag ccgtgatccc gggcgatgcg gtgaaggccg gatgcggttt cagcgtcaag
     8461 cgtgcacgat acgctgccgc ccgcaaagct tctgacagcc ggacggggct tgtcagccgg
     8521 aagctcaagc accggaagct ctccttctag ccgcttcagc caatacgctt cctgcttctg
     8581 atatccttct ttctcctgaa acgaccgctg ccagacggca tagtctttat attgaaggcg
     8641 catcggcgca agcgaacggc ctgcgtacag ctcgccgaat tctttaatca aggtgttgac
     8701 ggacacaccg tcagaaataa tatgatgcat atccgttaat aaaagatgac gttcgtctga
     8761 ttctttcacg agggccgcac ggaagagcgg cgcttcctcc agacaaaacg gccggacgaa
     8821 tgcgtcagct gactcggcct catccagctg aaacggtacg ctgtcatgga agcgctgcac
     8881 cggttcgccg tcaggccccg tttcaaagga cgttctgagc gactcatgcc gctccacaag
     8941 ctgccggaac gtctcctcca gccggccgcg gtcaagcggg cccgtcagtt ccagcacagc
     9001 cggcatattg tagccgacac cgccgtcttc aagctgctgg agcacataca tccgtttctg
     9061 cgccgaagac accggatagg tgtcctgttt ttgcgcaggc tgaatcgatt catacgggct
     9121 ctcttccaag tcctgaataa ccgaagcgag ctcttccacc gtcggccggg cgaagatgtc
     9181 ctgtaacggc acctgaacac cgaactcttt ggcgatgcgg gagacgagag ccgtcgcttt
     9241 taacgaatgg ccgccccgct caaaaaagtg atcccggatg ccgacggggc cgtttttcag
     9301 cacctcttcc caaagggcgc aaagcttcat ttccgtgacg ttccgcgggg cggtgtacgc
     9361 ctgtctgtct gccgctccgc cgggagccgg cagcgcgcgg cggtcaagtt ttccgttcgg
     9421 cgtgaccggc cactcggtca tctttatgaa ctgagccggc atcatgtagg ccggaagcgt
     9481 gccgcaagct ccgcccgcac gtcatcgctt tcccgtcctt cgatataggc ataaagcgcg
     9541 gtttcgccgt gttcggtccg ggcggtgacc gccgcctcac gaatgccgtc gatgcgccgg
     9601 atcgccgctt cgatttcccc cggttcaatc cggtagccgc ggactttcac ctgtccgtct
     9661 gaacgtccga gccattcaac aaggccgtct tctgtccagc gtgcgatatc tcccgtctga
     9721 tacatgcgtt ctcccggata aaacggatca tcgagaaaac gctcctccgt cagctcaggc
     9781 cggttcagat agccgcgggc cacccctgtc cccgcgatgt acagctctcc tgccacgccc
     9841 gcaggctgga tggttcctcc gctatctaat acatacagac gggcaccagg aacgggttta
     9901 ccaatcggaa gccttgtccg tccgctgtcc cgttttcggt cacagacgta aaacgccgca
     9961 tcaaccgtcg cttccgtcgg cccgtagccg tgaatgagca cggtctccgg cagaagatcg
    10021 gcaaaccggg cagccgtaag cggggaaaga gcttcccctc cggcaaacac gcgtgtcagt
    10081 gttctgccga ggcgtgttct tgtttctgca ggctctgttt ccagcgcgtc taaaaagctg
    10141 ttgaccatcg ccggaataaa atgcgcggtc gtcacctttt cagaagaaaa agcttcaatc
    10201 atccgcacag gatctttctc ccatccggca ggaagcagat acacggaggc gccggacatc
    10261 gtccaccaaa acaattgcca gatggaagca tcgaaagaaa aggatgattt cagcacgata
    10321 atatcctctt ccgtcaacgg gaactgccct tgcatccctg ataaaaaggc ggcggcctga
    10381 cggtgttcaa cagccactcc cttcggtgtt cccgtcgaac cggacgtata aatgatataa
    10441 gcgagcgaat cagcatccgc ttcttcagag acatcccctg tctccgtctc acttgtcaga
    10501 gaagaaagag acacttctag cgtttctccg gaaaaaccgg aaagggataa ccccggctgt
    10561 gcaagcagaa ggcaggcgcc ggagtcgtcg agcatatagc gcagcctgtc ctcaggatac
    10621 tccgggtcaa gcggcacata ggcgccgccc gcttttaaca cggcaagcac agaaaccacc
    10681 atctccggcg agcgttcggc gagtacgccg accatgcttt ctttgcggac gcctttttgg
    10741 cggagccgaa cagcgagcct gtctgtgtac tgatcgagct cagcgtacgt cagcatgccg
    10801 cccggaaaac ggagcgccgg acgatgcggc gaaagcgcgg cgcggcgggt gaacagcccg
    10861 tgaagcgtcg gagccggcgg ttcaaccgct tctgtacggt taaacgcagt taacacccgt
    10921 ttcttttcat tttcatccgc catatcaata tgccgaatca gctggtttgg atttctaacg
    10981 gcattttcaa cgatcgtcag caaatgagtt tgaattcgtt taatcgatgt tttagtaaat
    11041 aaagcggatt gataatcaaa attcagctca atcaatcccg tatctgtccg ctccttaatt
    11101 aaaatggaca gctcatttgc cgtatgtccg ctgaaaaaca tcgccgtttc ataatcgaaa
    11161 ccttctgcct gacgccacgc gagaggctgg tattgcatcg aaatcccgat gatattttgc
    11221 aggtcgtgat gagtctgcct taattcattc acaaaaagat tgtaaggata tttctggtgc
    11281 cgcataacag acagctgctc ttttcctacg ctgcggacaa aggacaggaa ctccgcatca
    11341 ggatctgccg tcattctgat cggcagtgtg ctgacgaaca tgccgagcat atccttttcg
    11401 agcctggagc cccggtttcc gtaataagtg ccgatggcaa tatccttttt agccgtcaga
    11461 cggctgatgc atatgtataa cgaagccata aacagagaga tgatgctgat attattttct
    11521 ttgcaaaaac gccggataga ttgttctaag gagtgagaaa gagtgattgt atctctggaa
    11581 gccgcagtgc tttgtctaag atgagaggtt cgttccgcca gtgaaaggtg ttccggaacg
    11641 gttcggtatg tttcagtcca aaatgaacgg tctttttgaa aacgggaaga ctgtaagtat
    11701 tgctgttctt tttccatgta gctgagatag gaaggtctgt gatgttcagt taaatcctcg
    11761 ccccgcatga tcttttggta gatatcaatg agctggttgc cgagaaggtt gagcgagatg
    11821 ccgtccatga taatatggtg aaattttgaa taaagccaaa cttcttcgtc tgacatgaca
    11881 agcagagtaa agtgatacag aggtgaatga aacagcttga acggaacacg ggtctgcgtg
    11941 tcaatccatg cgtcccgctc tgcctgatca gtatgagtaa aatcaacagt ctctagagaa
    12001 atcggccgat gccccgccag atacagctgg ggttctgatc cgtccccttc tgtcagttga
    12061 aacctgagcg aatcattttg cgagatagaa aaatctaaag catggcgcag tacgtcaaaa
    12121 tcgatgtccc ccctgaattt gacgcatgcc gcgagattgc agatacttgt gcccggttcg
    12181 agcagctccg taaaccacac tcttctttgg gcgtgagtta aagaataaac agtgttcttc
    12241 aatggaatcc ctccgcttca atttaagagg ataagaaagt gaaataatta caattaaatt
    12301 tcgacagcat atgactaaat catccatata agcattattt taaaacatat tttagaaatc
    12361 acaataaaaa attaaatttt ctctaacatt ttttagaata tagtatatat tcctcacttc
    12421 atttcttcat ttctataatc tttataccat gtaaaacggt atgtatgcac actgtaaact
    12481 ggttcttaaa cactataata aggaataaaa tgtataatta attgcgcttt taaaaaggtt
    12541 ttgcctcctg aaaagaagtt ttatgttaaa aaatgaaaaa tcggtgaaca agtaagaaag
    12601 tagcatgtaa aaaaaaggaa ggatattgcc gatattactt tttgaaaaga ttgattcata
    12661 atcgcaatat aatgttttac agacatcgaa aaaagccgaa tcctctaagg attcggccct
    12721 tcttattgat ttgccagcac gactgcgatt ttgtcttcaa tgtcttttcc gtcatcttcg
    12781 tcaagcagcc cgttttgaag cacggaaaaa ataagcgtat ctcctgtttt tgtgtctgca
    12841 tagccggcaa tcgaactgac tgatgttagt gacccggttt tcgctttaat tttgccctcc
    12901 gccggggtgc ccttcagccg gttccgaagg gttcctcccg tcattctgtc acttgcgccg
    12961 gcgacaggga gcgaccgaag gaaagccggg taccactttt ctttctgaac cgcatacaaa
    13021 agctctccga tttggccggc ggatacgccg ttaatatgag aaacgccgga tccgtctctt
    13081 gcaatcaatt catccggatt cagcccgaac gatttaagct ccgatttcat cacgtccaag
    13141 cccttttccc agctgccctc cccttttttc acttttccca tttccttgat cagaatttcg
    13201 gcgtgcccgt tgttgctcag tttcataaac ggaatcaata attctgaaag aggcatggat
    13261 gtccgtgatg tgacaagttg ggtgcggtgc ggcattcgcc ctgttctgat tttccctttt
    13321 acagttatac cctgtttagt aagcgcttgt ttccataaat ctaaagcata ggacgacgga
    13381 tcccacaccg ccgcccattc tcttgcctgt gccgagccga caggtatggt tccctttatc
    13441 gtaatcacat tgccaccgtg ctcccgttca accgtcaatt ctttcttttc atcagaagcg
    13501 acggttttca cttcattttt cacacgaacg acgtccgtat ggggagaaat cgaaatgcgc
    13561 ggctttttac cgggctgttt tgccgggctg atttccgcaa tcaccgttcc ggtatcataa
    13621 tcctcatttg gggaagcggt aagagctgat acttgcgcac cataatattg gccttcatcg
    13681 ctccacggaa gatcaactga atacctggta tcgtcatacc acgagtcatc cccgaccaga
    13741 tctcctttaa tgacatggat gcctctggct ttgacctgtt tagccatctt ctcaaaatca
    13801 gaaaccaata gggtcggatc gccttttccc ctgagataaa ggtttccgcg cagctgtttt
    13861 cctttcacgg cgccgtctgc ccgtacttct gtcttaaagg tgtaatcttc tccgagaacg
    13921 gaaagcgccg cagatgccgt cagcagcttc atcagtgatg caggcctcag ccgcatatct
    13981 tcccggctgc cgaacagcac ctcccctgtt tttgctgacc ggacactgac gcccgctgaa
    14041 gcccccttta aagcaggttc ttcatccaga atgtgttcca gctctttttg caaagtattt
    14101 ttttgatcag ccgccttagc cgcatcatca atataaggaa ctgcggcaat gatcaaaagc
    14161 agaatcaccg cgctcaagcg tttcacatat gttttcaatg ttatcccgcc tctttcctat
    14221 tcttcgtcat gcaaaatggt gatcctggat gacgcagccg cttcttcgcc cggtttcaga
    14281 atctgaagcc ctgtcagtga tgcaggctga ttcagattaa atgcatctgt aacggaagta
    14341 taaggctcaa gactgacaaa cccctgcttt ccgtcaccgt tatataccac ccaatgcttg
    14401 aaagacgtgt ctgcctgata caaaacggat aatttctcat ccggatgata aataacagct
    14461 tcgttattgc cgccgttccg tccggaagaa agaaaaacat cgtcaaactg tttatttttc
    14521 aaagagatcc catgatggaa cgcttcttta tcaggcacat ccaataaacg gcccgtcggc
    14581 acgaaacgtt catttaattc ccacatgcgg tcagccgtca gaaaaagacg ggatcgctct
    14641 tcattgaaaa caaatgtgga atgatagccg agcccccaag gaaaagcctc cgttcccttg
    14701 ttggtaatca gcgcccgctg cgtaaacaca ttgtctttta atgtataggt catccggaca
    14761 atgacatcgt gcggaaattg tttatgaaca cggggaatct ttgaaagatc aatttctgtt
    14821 tcgactgtca ttccatcccc ctcttctttc gctgccgcca ctttccaatg ctgattgtga
    14881 agaaagccgt gaatatgatt atgtttatcc tcttcgttta tctcgaattg atacgcgcgg
    14941 ccgtcaaaac gaaacgtccc gtccgtaatc cggttcggcg ggaataaaac gggaatgccg
    15001 tacagcatcg gttttgcgcg gaattgctcc gcagtttccg gttctctgag aagccgcata
    15061 ccggttcttt tatcccgaag cgatatgaca tttgatcccc actccggcac aatgatgcat
    15121 tcagcctgat cagtctccgc ttttatggct gaaaccccta aataagtcgt atgttcaatc
    15181 gtcataagca cctgcccttt ccttgttttc tagcatgtat aggaattcca ttttctaaac
    15241 tcattttcct gctctaaaaa aacatcgccc gtatgaactg agcgatgtgc ggtaaaacct
    15301 tattgaatca gccgggtaat ctgttttttc ttccatacaa accggtaata tccgtattgc
    15361 agcagcaggc tgacgacaaa agccgccgga taaccgaccc aaatgccgag aatgccgaga
    15421 ttcgtataat gagaaagaat aaaggccaca ggcacttcaa ttccccaaat cgcaaaaatg
    15481 ctgataatcg tcggccataa caccgtaccg ctcgcccgca ttgttgctga aacgatctga
    15541 gcgtgaccga aaatcaaata gctccaaagg gtaatcataa tcagattgcg ggcaatgtgg
    15601 agtgtatcct gatctgttaa aaacaaagcc agtatctgcc gggagaaggt gtaaatcagc
    15661 aggatcaaca ccccgccgat caaataattc aggccgatgc cgactttgat gacctgtttc
    15721 agccggccga attgattggc gccaatggat tgggcggcaa aaattgaaac ggcgataccg
    15781 aggcttaccg ccggcatctg cacataactc gccacttggt tgacgacccc gtaagcagcc
    15841 gtcgcgtttg atccgtaatg attgacaaat gaaatgaccg caatttcaga aagtgacacg
    15901 agaatcatat tgatgctcga cggaataccg agacggagta aaagcgcgag cagctttttg
    15961 tccattttaa gagaacggag cgcagtccgg tcaaatgcca atggatgttt ccttttccgc
    16021 aaataaacca tgagtacgat aaatgtcacg atgtttgaaa tcacggttgc atacgccgaa
    16081 ccgtaaatgc cgaacttcgg aagtccgaaa agcccgagaa tcaataaagg caaaagcccg
    16141 atgtttatga ctgtactgac gattaacgta taaaacggag tctttgaatc tcccgttccg
    16201 cgtaaaaatg tcgtatacgc aaaatataaa aacatcagcg gcattgcgca aaacaaaatg
    16261 cgcgcatatc ggacactgac atctattacg ttttccggcg ttcccatcag ccgcagaata
    16321 tcaagcgtaa acacactgcc gacaactgcc agaacaacac cgagcataaa ggtaaaagtc
    16381 agtgtagtgc cgacaatcgc cttcatcctc tcttcgtttt tcgcgccgta agcctgcccg
    16441 atcaaaatgg aacttcccga accgattccg atcgtaaagg agatcagcag aaaaaacagc
    16501 ggaaaaaaag acgatacggc ggcaagcgca tcaactccga gccaccttcc gacaaatacc
    16561 attccgacca attggccgac agattgcaat acattgctta aaagcagcgg cactaaaaac
    16621 agtgacatcg atcgccagac agactggccg cggccttccg ctgtttctaa atgatcttgt
    16681 acttccatat gtaggactcc ttttttgatt ttcttccatt ttattattca gcagacagct
    16741 tgtaaaaacc ttttgttcaa tgaaactctt tatctttttc tcacgtctta catggaaata
    16801 aaccataaaa ataaaaagtc cggaaaatat ttctgaaaag gtattgtaat cttaacgtaa
    16861 ttattgtaac atttgtaaca taagagaaag agattgattg aaggagagat tatatcatga
    16921 aaaaatggct attattcctc actactatta cattgattct gtcattgggc actgcggcga
    16981 ccgcaaaaaa tgcacctaat gaccttacac aaaaacaagc gcttcagctg gccctgtcag
    17041 cgagagaaca tttctggaac acgatgagcg gcggtgcgct taaaacaaac gaaaattgca
    17101 cttctgaacc gtttgaatat caaaatctgc aatatgtatt tatgtgcaaa gacctcggaa
    17161 caaaagcaaa agccgtaaaa tatctgacac ccgcttttac aaagcaagcg attgacaaag
    17221 ggctcaaaga ttaccacttc actgtaaaag acggcaaatt ggctgttccg gtcggcgacg
    17281 gagataacct cctgaattgg aaaaaagcaa aaatgactct tctttctaaa aaaggaagcg
    17341 ctcaaacata ccgcttcact gtgccgactc ttgacggttc tccgtcagct aaacgcgatg
    17401 taacattcgt aaaagaaaac aacgtttgga aagtcaatca atttgatgct gtcatataag
    17461 aaaaagcccg cttgcttaca gcgggctttt ttcacatcat ttccaccagg ttctcacaaa
    17521 atattcaact caaaaacccc ttgtataaca aggggttttt gttttaccga cattattcag
    17581 ctgcgccttt ctcatacaaa aaacgctcta ggagagattc gaactcccga cctgcagttt
    17641 aggaaactgc tgcactatcc gctgtgctac tagagcctgc ttctattata gtaacgctgg
    17701 cggccgtttt tttcaagtct acagccctcc gaacacttta taggcggctc tcgtcgtatc
    17761 ttcatctatt ccgatataac gcattgtaat agacggagaa gaatgattca aaatcctctg
    17821 cagttcagca atgtcttttg tcctctgata aaaatgatac ccgaacgtct ttctaagcgt
    17881 atgcgtcccg atttcctcca acccgcaagc ggcagccgct tcctttaata ttctgtatgc
    17941 ctgaatccgg gatatgggct tattcgtccg tttcgattta aacaaatagt catcctcttt
    18001 catgtctttt gtataagcgt atatgtcggc ctttaaagac tccagtatca gaatttttct
    18061 tttctttctc gttttgcttt cggttgccca cacatggtct ttgttcctta catccctcac
    18121 gcgaagcggc agaacatctg aaatccgcag tgcgctgttc atgccgaaaa taaataaaaa
    18181 ataatcacga tcactttttt tcattaaata ctgtttgact tcctggatct tctccaaact
    18241 tcggatcggc tgtacgatat gcatcaaaaa accccttata attggtaaag taacatattg
    18301 agcattatgt tactattata accgaaaccc gttgaatgat aaaggataaa gggtcttatg
    18361 taacataata tacatagtgt tacataaggt gaatcagata agcagtttca acgaattcct
    18421 caaaaacatc attttcagcc cgttgacaag cttttaaaca aatagatact taaggtatta
    18481 aaaaatgaaa acaacggcct taaaatgaaa tctgagcatc cgtttttttg tgagcaaccg
    18541 aaaaaaatga aaaaaaaggg gctgggacaa aacccacctc taagacgaaa aaaacggtga
    18601 aattttacga cgagtaaact ttcaccgt
//
