LOCUS       NZ_JAIONG010000033     15534 bp    DNA     linear   CON 22-NOV-2024
DEFINITION  Bacillus amyloliquefaciens strain SN_Endo51 sequence33, whole genome
            shotgun sequence.
ACCESSION   NZ_JAIONG010000033
VERSION     NZ_JAIONG010000033.1
KEYWORDS    WGS; RefSeq.
SOURCE      Bacillus amyloliquefaciens
  ORGANISM  Bacillus amyloliquefaciens
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Bacillaceae;
            Bacillus; Bacillus amyloliquefaciens group.
REFERENCE   1  (bases 1 to 29395)
  AUTHORS   Roy,M. and Dutta,T.K.
  TITLE     Community profile and biosynthetic gene analysis from end to end
            microbiomes of the medicinal mangrove Suaeda monoica Forssk. ex J.F.
            Gmel of Indian Sundarbans
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 29395)
  AUTHORS   Roy,M. and Dutta,T.K.
  TITLE     Direct Submission
  JOURNAL   Submitted (03-SEP-2021) Microbiology, Bose Institute, P-1/12, CIT
            Road Scheme VIIM, Kolkata, West Bengal 700054, India
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 30-MAY-2021
            Assembly Method                   :: SPAdes v. 25.05.2021
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 10.0x
            Sequencing Technology             :: Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_020179775.1-RS_2024_11_20
            Annotation Date                   :: 11/20/2024 08:35:12
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,314
            CDSs (total)                      :: 4,259
            Genes (coding)                    :: 4,097
            CDSs (with protein)               :: 4,097
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 46
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 162
            CDSs (without protein)            :: 162
            Pseudo Genes (ambiguous residues) :: 0 of 162
            Pseudo Genes (frameshifted)       :: 91 of 162
            Pseudo Genes (incomplete)         :: 72 of 162
            Pseudo Genes (internal stop)      :: 30 of 162
            Pseudo Genes (multiple problems)  :: 28 of 162
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 19:57:53
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 13861
            Orig. end                         :: 29395
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JAIONG010000033.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..15534
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="terpene"
                     /region_number="1"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..15534
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..15534
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="True"
                     /core_location="[10000:10741](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10741
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    945..960
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: medium, score: 22.1"
                     /tool="antismash"
     misc_feature    complement(1065..1079)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 20.88"
                     /tool="antismash"
     misc_feature    complement(2372..2386)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 18.38"
                     /tool="antismash"
     gene            2897..3190
                     /locus_tag="K8B35_RS19985"
     CDS             2897..3190
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017417418.1"
                     /locus_tag="K8B35_RS19985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_017417418.1"
                     /transl_table=11
                     /translation="MADSAEGTCELCGRHHVRLTEHHLTPKEEGGTFLPTAMLCIPCHK
                     QVHALYTNQELAARLAGIEELRRDPKLARFVKWIRKQPPKKLVKTKKANERT"
     gene            complement(3231..3449)
                     /locus_tag="K8B35_RS19990"
     CDS             complement(3231..3449)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003155143.1"
                     /locus_tag="K8B35_RS19990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="spore germination protein"
                     /protein_id="WP_003155143.1"
                     /transl_table=11
                     /translation="MPAITGPIAINSISGGVVNFGDSFYLSPKSSSKSALGSGAGNTGD
                     FLLLNNVVNATNYIDPDVSDQNVVGNA"
     gene            complement(3489..3884)
                     /locus_tag="K8B35_RS19995"
     CDS             complement(3489..3884)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007610514.1"
                     /locus_tag="K8B35_RS19995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="spore germination protein GerPE"
                     /protein_id="WP_159353992.1"
                     /transl_table=11
                     /translation="MLKRISRLRNAKINSVGIASVFQAGDTNEINMRVTVLADQRSLAV
                     YRDDEGSFNKKEYQIFRQPAVMPLPETGVQSAFCHENPSIRVRDVKVQGVSSASVVQIG
                     STSIVLGDSRLKHIRQIFTSSSQSQQP"
     gene            complement(3884..4060)
                     /locus_tag="K8B35_RS20000"
     CDS             complement(3884..4060)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388950.1"
                     /locus_tag="K8B35_RS20000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_003155141.1"
                     /transl_table=11
                     /translation="MIFTVINRNIEVGDIRSTGVSSSSLLLIGDTDSVYLSSIFDTPPE
                     SLIIGPYVPLAPE"
     gene            complement(4057..4674)
                     /locus_tag="K8B35_RS20005"
     CDS             complement(4057..4674)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016938284.1"
                     /locus_tag="K8B35_RS20005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="spore germination protein GerPC"
                     /protein_id="WP_159354698.1"
                     /transl_table=11
                     /translation="MYDQSVSSYLQNLNSFVQQQAQQIQELERQLKEFQNEISTLKQQP
                     STRIDRLEYKFDQLKIERLEGTLNIGLNPTDPNAVQNFEVGQTSPQVGMMQQEQAGQQM
                     QQIRQNVDMYLNEEIPALLEKLETQYESRLDEANKYHIIEDIRKQMDSRIQYYLSHVPK
                     EENTAPAQYAEQIAEHVKRDIVRAVEHFIKHIPGEVKGDDPS"
     gene            complement(4710..4946)
                     /locus_tag="K8B35_RS20010"
     CDS             complement(4710..4946)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015483061.1"
                     /locus_tag="K8B35_RS20010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="spore germination protein GerPB"
                     /protein_id="WP_159353993.1"
                     /transl_table=11
                     /translation="MNFYVNQSIHINYMRVESVSNSSILQIGSAGSIKSLSNLYNTGSY
                     VELAPPVTAGQQTVTTGGGPGTSSFVPLQPPSR"
     misc_feature    complement(4912..4925)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: medium, score: 23.16"
                     /tool="antismash"
     gene            complement(4959..5180)
                     /locus_tag="K8B35_RS20015"
     CDS             complement(4959..5180)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388953.1"
                     /locus_tag="K8B35_RS20015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="spore germination protein"
                     /protein_id="WP_003155135.1"
                     /transl_table=11
                     /translation="MPAIVGAFKINAVGTSGVVHIGDCITISPKAEVKTFAGAGSFNTG
                     DNLTLTNYRNSTNVYDNDVIDQPMAGNA"
     gene            complement(5370..5585)
                     /locus_tag="K8B35_RS20020"
     CDS             complement(5370..5585)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017417420.1"
                     /locus_tag="K8B35_RS20020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="aspartyl-phosphate phosphatase Spo0E family
                     protein"
                     /protein_id="WP_014417374.1"
                     /transl_table=11
                     /translation="MNKIEEKRLTLFETAQKFGINATETIRCSQELDSLLNGCRGGLIQ
                     QTKDSGLNPSVQIEHGRTAGKKEAFS"
     misc_feature    5664..5684
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: medium, score: 26.99"
                     /tool="antismash"
     gene            5803..6708
                     /locus_tag="K8B35_RS20025"
     CDS             5803..6708
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388956.1"
                     /locus_tag="K8B35_RS20025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="fumarylacetoacetate hydrolase family protein"
                     /protein_id="WP_159353994.1"
                     /transl_table=11
                     /translation="MKFATGELNSRTFVGLIIDDDKILDLQKAEKKLFELETIPGSLIE
                     CIQKGDKFVAHAGQLAEWAEKPNDESGSFMYALSDVKLCAPIPRPSKNVICIGKNYRDH
                     AVEMGSEADIPEHPMVFTKAPAAVTGHGETVNSHLDVTEQLDYEGELAVIISKSGSHIS
                     KEHALDHIFGYTIVNDITARDLQKKHKQFFIGKSLDTTCPMGPVIVHKSAVSDPQSLKV
                     ETRVNGELRQSGSTGDMIFPIAELIETLSKGMTLEAGDIIATGTPSGVGKGFKPPKFLK
                     PGDRIDITIEPIGTLSNQIG"
     gene            6801..7157
                     /locus_tag="K8B35_RS20030"
     CDS             6801..7157
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388957.1"
                     /locus_tag="K8B35_RS20030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="YisL family protein"
                     /protein_id="WP_003155128.1"
                     /transl_table=11
                     /translation="MTHWHITSWVVALILVFVSYGLYGAGKAKGAKITHMILRLFYIII
                     ILTGAELFVRFANWNGEYAGKMLLGIITIGLMEMLVIRKKKGKSTGGLWIGFIIVLVLT
                     VLLGLHLPIGFHVF"
     gene            complement(7357..7899)
                     /locus_tag="K8B35_RS20035"
     CDS             complement(7357..7899)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014417377.1"
                     /locus_tag="K8B35_RS20035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF2777 family protein"
                     /protein_id="WP_201448508.1"
                     /transl_table=11
                     /translation="MKRKQFFSEKNKWGRGTLMIEDGICLVENDEGDILLADSLGNADV
                     LMKRGGRWQPARICGGAAEIGADTIPLLGGEEIRYEKAVKRPLLTLLDSLDDETFLLFL
                     SHLHGFGLSVYDCVFSYNQALFSGEGVSFYHFSADDAQCALQHHRGSSGKHDRFEWTAS
                     DGRRSIMYSAAKQDGTA"
     gene            8075..9916
                     /gene="asnB"
                     /locus_tag="K8B35_RS20040"
     CDS             8075..9916
                     /EC_number="6.3.5.4"
                     /GO_function="GO:0004066 - asparagine synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA]"
                     /GO_process="GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="asnB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GATase_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Asn_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177: asparagine synthase (glutamine-hydrolyzing)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016938277.1"
                     /locus_tag="K8B35_RS20040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="WP_159353996.1"
                     /sec_met_domain="GATase_7 (E-value: 6.1e-50, bitscore:
                     159.1, seeds: 307, tool: rule-based-clusters)"
                     /sec_met_domain="Asn_synthase (E-value: 4.3e-101, bitscore:
                     329.8, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MCGIAGWVDFQKQLVQEKHIMNNMIDTLSKRGPDDSNVWGEPHVL
                     FGHKRLSVVDIEGGRQPMACTHQEETYTIIYNGELYNTEELRKELQARGHRFERTSDTE
                     VLLHSYIEWREECVNRLNGIFAFAIWDEKRERLFGARDRLGVKPFFYKEHGSSFLFGSE
                     LKAILAHPDVKARTDSGGLAEVFGLGPSRTPGCGVFKGIHEVRPAHAFTFSKDGLSIWR
                     YWNVKSEKHTDSFDETAAHIRYLFQDAVTRQLVSDVPVCTFLSGGLDSSAITAIAAAHF
                     EKQGRDPLHTYSIDYEENSKFFKASAFQPNDDGPWIDKMTNAYGTQHHKCVITQDQLVE
                     HLEESVLVRDLPGMADVDSSLLWFCREIKKDFVVSLSGECADEIFGGYPWFHTAAEEAG
                     FPWMRSTEERITLLDEKWQKRLNLREYVNARYEETIAETPLLDGETGTDKARRQLFYLN
                     MLWFMTNLLDRKDRMSMGASLEVRVPFADHRLVEYVWNIPWEMKMHGSREKGILRKALE
                     GLLPEDILYRKKSPYPKTHHPKYTQGVTEWLKTILQQKDSVLHTLLDRKKLEMLLETEG
                     SSFQVPWFGQLMKGPQLIAHLAQIHTWFEAYRIDIEE"
     gene            10001..10741
                     /locus_tag="K8B35_RS20045"
     CDS             10001..10741
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014417379.1"
                     /locus_tag="K8B35_RS20045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="squalene/phytoene synthase family protein"
                     /protein_id="WP_053285064.1"
                     /sec_met_domain="phytoene_synt (E-value: 1.9e-26, bitscore:
                     83.6, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 1.7e-32,
                     bitscore: 103.5, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTEYETCAQLAEAHFPLYKRTFSTLPPKNRRAAWAVLALFHEADR
                     LDVQELGGFEQAAQDFLNGARADGFLWEALADVRQQFALEEEPLREFIAGQISDREKVT
                     YQEFDDLLMYAGQTGGALGLLLLPVCARRNQEKLRHAAVSLGAAIQLTRVLLGVHTDER
                     AKKRLPRHVMKQFGYTEEELESHTVNKAFMNVWEYIAFEAEAYFEEASEALELFPLYSR
                     PAVTNLLAYYRSELGDMRKQLSQA"
     gene            complement(10777..12144)
                     /locus_tag="K8B35_RS20050"
     CDS             complement(10777..12144)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0042910 - xenobiotic transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0006855 - xenobiotic transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1086: MATE efflux
                     family protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388962.1"
                     /locus_tag="K8B35_RS20050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MATE family efflux transporter"
                     /protein_id="WP_003155121.1"
                     /transl_table=11
                     /translation="MKQAILKRAAFKQSSDHKLSLYALTWPIFIEVSLYMFMGNADTLM
                     LSQYSDNSVAAVGVSNQILNLIIVMFSFIATGTTIVISQFLGSKQKKEAQEVAYVSIGA
                     NFVISLAISAAIFFAAVPLLHVMGLSNELMPDAKVFLQVVGGLSFIQALIMTFSAILKS
                     YGHTKDTMFVTIGMNILNIAGNFLVIFGPLGLPVLGVAGVAMSTSFARIIGLIAMIVIV
                     KKRIGLGLTWQKIFHVHKEHLRKLLKIGIPSAGEQLSYNISQMVVTYFIAIMGAQALTT
                     KVYTQNITMFILLFGTAISQGTQILIGRYIGAKRFDDAYDRCMKSLYWALGIAALTSVI
                     MTLFSKQLIGIFTSSPDIIATASMLIAMTIILEPGRSFNVIIINSLRAAGDAKFPVYMA
                     MISMWGIGLPLAYLFGIHFGLGLMGIWISFIADEWVRGILMYRRWRSRIWIQKGIA"
     misc_feature    12197..12210
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 20.16"
                     /tool="antismash"
     gene            12267..13130
                     /locus_tag="K8B35_RS20055"
     CDS             12267..13130
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1287: AraC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388963.1"
                     /locus_tag="K8B35_RS20055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="AraC family transcriptional regulator"
                     /protein_id="WP_007409155.1"
                     /transl_table=11
                     /translation="MSFLEFTVPPFPVFIAAGEGVFKKGETHVRRVFPVFDLLYVKEGV
                     LYITEDENAFSVEAGEYILLSPGLEHYGTKGSEETTSYSWLHFEGAAYEVTETTGNNWS
                     ELRRKKGSFEEPSRYRLSLPQKGKVRRPQFMAGQFSVLTDDSAENSDLPLRKQILFEEL
                     LLHLQKEAFQIPSAKERVAWEAARYLQEHYQEKTTIKALSSALHYNQDYVTRCMQQVLG
                     VTPGQYTNKVRMTEAKRLLSATNDKMGAIADAIGMEDPTYFSKLFKQIEGISPLEYRKF
                     VSRKTD"
     gene            13166..14191
                     /locus_tag="K8B35_RS20060"
     CDS             13166..14191
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /function="Transcriptional regulators"
                     /gene_functions="regulatory (smcogs) SMCOG1078: LacI family
                     transcription regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014417382.1"
                     /locus_tag="K8B35_RS20060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="WP_014417382.1"
                     /transl_table=11
                     /translation="MKMTIYDVAEKAGVSISTVSRVINNTGRISDKTRRMVLRVMEEMD
                     YHPNVHASALTGKKTNMIGLITPDISNPFFGELAKSIEDSAGALGFHIIICSTDYQPEK
                     ETKYFSMLRQKQADGIIFATGLDHDDSVTALDDMVKSGIPLAMITQDKPLAPMDVVIID
                     DFLGGYTAAEHLISLGHKRIACIVGNGSTTGERDRIKGFRKAMREAGMTLDESLIIPTE
                     YSLESGKQAAGELFDRDLPTAVFAFNDVLSCAAIQAARSRGIRVPEDLSVIGFDNTILA
                     EMTAPPLTTISQPIREMGRRVVELLIDEIQGKKKTKSKIILSPELVIRHSTAPAKTRPQ
                     R"
     misc_feature    14208..14222
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 21.27"
                     /tool="antismash"
     misc_feature    14238..14254
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 22.44"
                     /tool="antismash"
     gene            14414..15445
                     /gene="iolG"
                     /locus_tag="K8B35_RS20065"
     CDS             14414..15445
                     /EC_number="1.1.1.18"
                     /GO_function="GO:0050112 - inositol 2-dehydrogenase (NAD+)
                     activity [Evidence IEA]"
                     /GO_process="GO:0019310 - inositol catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="iolG"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GFO_IDH_MocA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GFO_IDH_MocA_C3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1079: oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017417427.1"
                     /locus_tag="K8B35_RS20065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="inositol 2-dehydrogenase"
                     /protein_id="WP_159353997.1"
                     /sec_met_domain="GFO_IDH_MocA (E-value: 1.4e-36, bitscore:
                     116.7, seeds: 39, tool: rule-based-clusters)"
                     /sec_met_domain="GFO_IDH_MocA_C3 (E-value: 2e-27, bitscore:
                     86.5, seeds: 4226, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDQVRCAVLGLGRLGYFHAKHLVSEVRGAELAAVCDPMKGKAEA
                     CAKELGIAKWTENPYDLLEDHTIDAVIIVTPTSTHAEMIMKAAENGKHIFVEKPLTLSL
                     EESKEVMKKIEETGVICQVGFMRRFDPAYADAKRRIDAGEIGRPIYYKGFTRDQGAPPA
                     EFIKHSGGLFIDCSIHDYDIARYLMNAEDTSVCGHGRILKHPFMEECGDVDQALTYLEF
                     DSGAAGDVEASRNSPYGHDIRAEIIGTAGSILVGTLRKSHVTILTESGSSYEIIPDFQA
                     RFKDAYRLELEHFAECVKKGETPIVTDVDATINLEIGIAATESFKTGRPVKLTPGAFGY
                     AGL"
ORIGIN
        1 cctgtttaat ctggaacagt acggggacag gcttgtcaaa aaattgcggc ggcgggcgca
       61 ggaagcggca gcgaaaaaaa atgaaatgct ggccgaacaa tccggcctcg gagacgcagg
      121 agaagatgcg ctgaaacagg ctgaacagca gtttcacgaa gcgaacgaac ggcttgaagc
      181 agctgagaag aaacgggtcc gggcaaaaga gcgttttgag aatcaccagg aaatttggaa
      241 cctgcagaca gaaagagatg aatatgagcg ccgggagaaa aagcttgagg aaagacgccc
      301 gtacatcacg gatttgactg agcgtcttaa agaggctgaa acagctctcg cccttgagcc
      361 gtacgcagac cgctacacag aagccgtccg ccggaagcag cgcgccgaac aggagcacga
      421 actggccaaa cggaaatcag aggcggaaac cgtttcattt acccggcaaa atgaagccta
      481 tgaagcatgg cgggcccata aggccgaaca ggagccgaag cttgtcaagg aagaagagct
      541 gtatcaaaga ctttcagcca tagaacaaaa actgcttgaa gcgaaaaaag aagcggaaaa
      601 aacaaatgcg gaacacagca aaaaagagga agaatacgaa gccgcctcga aacagctggc
      661 cggagtgaaa gaccgcctga cccgcggcca aaacaggcag aatgagctga aagaagagct
      721 gaaagcagtt caagtgaccg ccgatgaacg gaaaaaatgc cagaccgcag cacagctggc
      781 ggcgggcttt cagcagacac aggaacaaat cacgaaagaa cgggccaatc tgacaacgca
      841 gctgaaaaac gtggagaagc tgaacggaga aagcgagtcg ctcacagcga aagcgaaaac
      901 ggaagaggaa gacattacgc gcgcttatca aacgcttcaa accgtttacc atatggtctg
      961 tgaaacggag cgttcactga aagccgcagc cgaacgggct gacaaaacgc aagccgatct
     1021 ccgcaggcgc tcagaggaag cgagaacggc tgcattaaca aaagaattat cggaaaaact
     1081 aatcgaagga aagccttgtc ctgtatgcgg ctcgacgcag catgaccgcc ctcgttccgc
     1141 tcatgaaaca ttctcgcctg atacagctgt acaggaacag ctgcagcagg ttgaagcact
     1201 actttctgag gcggcggctc tttctcagga agtgctgaca gccaaggttg cattagaaga
     1261 acagtcgggg cgttttaccg aagaatgtcc gtttctgcaa agcgcccggg ttccggagct
     1321 ggaagccgct tcctccatca gcggacgccc gcttgatgaa gcgttcagcg ccgtccgctt
     1381 ggagtggaaa caaatgaaac aggatatgct gtcggtaaaa gagaaggtca caagactgat
     1441 cagcgcgcat cagcagacgg tgaaacaagc tgagcagctt gccgaacgaa tccgctacga
     1501 ggaaaaagaa gccgaccgtc tcagacattc attagaagag cttgaatcgc tgtcagaaag
     1561 ccgattgaat cagtacaacg aagtctgcgg tgatattccg ccaaaccgga ttgactcctg
     1621 gcaggcttcg atagatgaga aggacaggca ggcagaagaa tgtgagaagc gcattgaaac
     1681 aagcatcgca ttcctcaagg aacatgaaga ggagaaagaa cgcctgcagg agatgaagca
     1741 tcggcttgaa cgggaacggc tcgagcttca ctatgcgtcg gagcgcctgc agcaggtgat
     1801 tgacggatat gaacaagagc tcggaacagc agctgaagaa acatcaattt ccgcaaagct
     1861 tgaagcggtg cggcaggaat tacagctgtt aaaatcgaaa gaacagtccc tattcgatgc
     1921 gctgaagcgg gcgcagcaat cactgaatga cgcaaaaggc cgggaatccg ggagtctcat
     1981 gtcactcagg gatgctgaga cttcccttga gaaagcgcaa aacgactggc gcgtgaggtc
     2041 aaaagacacc gggtttaccg agccggacca agtcaaaaaa agtctgcttc cgcaagggcg
     2101 tgcagaggaa atgaaaaaag aaattgatga gttcctggac acctcaaaac agctatcggc
     2161 aaatatcagc cgtgttactg ataaattagc cgaccgccgg atatcagagg aagaatggac
     2221 agcatccgtt tctctgctga agcaggcaga ggctgagtca ggcgccgcca tggaggaaaa
     2281 aggagcacag gcaaaagcct tcgcggttat gcaaaaacag cataagcgct ttaaagagat
     2341 tgaagccgaa ctgaaaagct ggcagacaca gattgacagg cttgataagc tccagtctgt
     2401 atgtaaaggc aatacattcg tcgaattttt agcggaagaa cagctggaaa gcgtggctcg
     2461 ggacgcctct gcccgtctcg gagcgctgac aaggcagcgg tatgccatat tagtcgattc
     2521 agaaggcggt ttcgtcatgc gtgatgatgc gaacggaggc gtcaaacggc ccgtatcaag
     2581 cctttccggc ggggagacgt ttctgacatc gctgtcgctt gcgcttgcct tgtccgccca
     2641 gattcagctg cgggggcaat acccgctgca attctttttc ttagatgaag gattcgggac
     2701 tcttgaccaa gggctcttag acaccgttgt cacagcgctc gaaaagctgc aatcggacaa
     2761 cttatccgtc ggagtgatca gccatgtgca ggagctgaga gcgcgtctgc cgaaaaaatt
     2821 aatcgttcat ccgtccgaac cgggcgggaa aggcacccgg gtcacattgg agatcatgta
     2881 gaaaggagaa ggaattatgg ccgattctgc cgagggcaca tgtgaattat gcggccgcca
     2941 tcatgtgcgg ctgacggagc accacttaac gcctaaggaa gaaggcggga cattccttcc
     3001 gaccgcaatg ctctgcatcc cttgtcataa acaggttcac gcgctctata cgaatcagga
     3061 gcttgcggca aggctcgcgg gaatagaaga gctgcggcgt gacccgaaac tcgcgcggtt
     3121 tgtgaaatgg atcagaaaac agccgccaaa aaagcttgta aaaacaaaaa aagcaaatga
     3181 acgaacataa cgcctaaaaa gcagccctct tctgaaagag cggctgcttt ttaggcgttt
     3241 ccgaccacat tttgatcgct gacatcgggg tctatatagt ttgtcgcatt gacaacgttg
     3301 tttaataaca ggaaatctcc ggtattgcct gctcccgaac cgagcgcaga tttagaagag
     3361 ctttttggag aaagataaaa ggaatcacca aagtttacga ctccgcccga tatggaattg
     3421 atagctatag gtccggtaat tgctggcata aacgacaccc tttatagaag tctcaccgtc
     3481 attatatgtc agggctgctg tgattgtgag cttgatgtga agatctgcct aatatgtttc
     3541 agccgcgaat ctcccagaac gattgacgtc gatccgattt gaaccacgga cgctgacgat
     3601 accccttgaa ctttcacatc ccttacccga attgaagggt tttcatggca gaatgcgctt
     3661 tggactcccg tttccggtaa cggcatgacg gccggctgcc gaaagatctg gtattctttt
     3721 ttgttaaatg agccttcatc atctctgtat acagcaagac tacgctgatc ggccaatact
     3781 gtgacccgca tattgatttc attcgtatcg cctgcttgaa agacactcgc aattccgact
     3841 gaattgattt tggcgttccg gaggcgtgaa atgcgcttta acattattcc ggcgccagcg
     3901 gcacataagg cccgataata agagattccg gaggcgtgtc aaagatggaa gacagataga
     3961 cggaatcggt gtcgccgatt aataataagg aagaactgga tacaccggta gaccggatgt
     4021 cgccgacttc aatattccgg ttaatcactg taaaaatcat gacggatcat cacctttcac
     4081 ttcaccaggt atgtgcttaa taaagtgctc gacggccctg acaatatcac gcttcacatg
     4141 ttcggcaatc tgctcggcat attgcgcggg cgccgtattt tcttctttcg ggacatggga
     4201 cagataatac tgaatccggc tgtccatctg ctttctgata tcttcaataa tatgatattt
     4261 gttcgcttcg tccagcctgc tctcatactg agtttcgagc ttctctaaaa gcgcggggat
     4321 ttcttcattc agatacatat cgacgttttg gcggatttgc tgcatttgct ggcccgcctg
     4381 ttcctgctgc atcattccga cctgcggaga tgtctggccg acttcgaagt tttgcacggc
     4441 attcggatca gtcggattca atccgatatt cagcgttcct tccagccgtt caattttcag
     4501 ctgatcaaat ttatactcga gccgatcgat tcttgtagaa ggctgctgct tcagcgttga
     4561 aatttcattt tggaattctt tcagctgccg ttcgagctcc tgaatctgct gcgcctgctg
     4621 ctggacgaaa gaatttaaat tctgcaggta ggatgaaacg gattgatcat acatgacatt
     4681 cacctcgcgt ctcgtttcct tcattaaaac taccggcttg gcggctggag cggtacaaat
     4741 gatgaggtgc cgggacctcc ccctgttgtt acagtctgct gccccgcggt gacaggcggc
     4801 gccagctcaa cataactccc tgtattgtac agattggaaa gagatttaat tgaaccggcg
     4861 cttccgattt gcagtatgga ggaattgctg acagattcta cacgcatgta attgatatgg
     4921 atcgactgat tgacgtaaaa attcatacgg cgcctccttt atgcgtttcc tgccatcggc
     4981 tgatcgatta catcattatc gtacacattc gttgaattcc tgtaattcgt cagtgtgaga
     5041 ttgtctccgg tattgaagct gcccgctccg gcaaatgtct taacctctgc ttttggagaa
     5101 atggtgatgc agtcgcctat atgaacgact ccgctcgtac cgacggcatt aattttaaac
     5161 gctccgacaa ttgcgggcat acgagcacat ccttttcgtg aagattttca tgactgcact
     5221 ccaggagctt atctgggctg cctgcctaaa atagcttatg acaaatgcac atttttgtga
     5281 gcggaaaaaa ctttagacgt aaaaacaccg gcgctatacg catgccgggc cttatacata
     5341 aatgatacag atttatatac acatcacgtt tatgagaaag cctctttttt tcctgcggtg
     5401 cggccgtgct caatctgtac ggacgggttc agcccgctgt ctttcgtttg ttggatgagc
     5461 ccgccccggc acccgtttaa aaggctgtcc agctcctggc tacacctgat ggtctccgtc
     5521 gcattgattc cgaatttttg cgctgtctcg aataaagtta atcttttttc ttcaattttg
     5581 ttcatcgtgt gatctccaat tctcgattat tttggaaaac ataggatgat aatagtataa
     5641 cccattttgt ccaagaaggt tttatttcgt caatatgact aaaaaagtga caatttttga
     5701 tactctttta cacttatttt cagcctgttt aaaagaggaa tttcccgcct ggaggaagaa
     5761 tacataaagg aatgccagat ttaaaaatga tgggggatta acatgaaatt tgcgacaggg
     5821 gaactgaaca gccgaacatt tgtcggtctg atcattgatg atgacaaaat cttagatctg
     5881 caaaaggctg aaaaaaaatt gtttgaactt gagacgattc cgggttcgct gatcgagtgc
     5941 attcaaaaag gagataagtt tgtcgcgcat gccggacagc ttgcggaatg ggcggaaaaa
     6001 ccgaatgacg agtcgggttc atttatgtat gcgctgtctg acgtaaagct ttgcgcgcct
     6061 attccgagac cttcaaagaa cgtgatctgc atcgggaaaa attatcgtga tcatgccgtt
     6121 gaaatgggga gtgaggctga tataccggag catcccatgg tttttacgaa agcccccgct
     6181 gccgttacag gacacggaga aacagtgaac agccacttgg acgtaacgga gcagcttgat
     6241 tatgaagggg agcttgcggt aatcatatca aaaagcggat cgcacatctc caaagaacat
     6301 gcgcttgatc atatattcgg ctatacaatt gtaaatgata taacagcgcg cgatctgcag
     6361 aaaaaacata agcagttttt tatcggcaaa agcctggata cgacatgccc gatgggcccg
     6421 gtcattgtac ataagtcggc cgtcagtgat ccgcaaagcc tgaaagttga aacgcgggtg
     6481 aacggagaac tgcgccaatc aggatcaacg ggcgacatga tttttccgat agctgaatta
     6541 atcgagacgc tgtcaaaagg gatgacgctt gaagccggtg acattatagc gacggggacg
     6601 ccgtccggtg tcggaaaagg gtttaagccg ccgaaatttt taaagccggg ggaccgcatt
     6661 gacattacaa ttgaaccgat cggcacgctg tcgaaccaaa tcggataatt gtgtgtcttt
     6721 cgcacgattg ataatgctcc gggtggcttg ttgtggtacc ataagtgagg cagattgatc
     6781 gataggggga attgaacata atgacacatt ggcatattac ttcatgggtc gttgcgctta
     6841 tcctggtgtt tgtcagctac gggctgtacg gtgccggaaa agcgaagggc gcaaaaatta
     6901 cgcatatgat tctgcgctta ttctacatta ttattattct gaccggagct gagcttttcg
     6961 tccgttttgc gaattggaac ggagaatacg ccggaaaaat gctgctcggc atcattacca
     7021 tcggactgat ggaaatgctc gtcatccgta agaaaaaagg caaatcaacc ggcggactgt
     7081 ggatcggttt tattatcgtg ctcgtcctga cggtgctgct cggccttcac ttgccgatcg
     7141 gctttcacgt attttaatca gtcgcttgaa aaacccggat gcatccgggt ttttttagtt
     7201 gcgcatacat tttgcgcaac tgtgccagcg tcaatcactc tcgttaccgc aaaagctacg
     7261 gctgtaaagg gtaaaagcaa acgccgggcg tcaatcagcg tgaaaaacaa agctaaatac
     7321 atcaggcggc acctatttaa aagtgccgcc tgtttgttat gcggtgccgt cttgttttgc
     7381 cgctgaatac ataatggagc gccgcccgtc agatgccgtc cattcaaatc tgtcgtgttt
     7441 acccgagctg ccgcggtgat gctgcagggc gcattgtgcg tcatccgccg agaagtgata
     7501 aaacgaaacg ccttcaccgg aaaacagcgc ctgattgtag gaaaatacgc aatcatatac
     7561 agacaggccg aacccgtgaa gatggctgag aaacagcaga aacgtttcat cgtccagcga
     7621 atcgagcaag gttaacagcg gccgtttgac cgccttttca taacggattt cttccccgcc
     7681 gagcaggggg atggtgtcag cgccgatttc ggccgcaccg ccgcaaatcc gtgccggctg
     7741 ccatctgccg ccgcgtttca tcaatacgtc tgcgtttcct agactgtctg caagcaggat
     7801 atcgccttca tcgttttcga cgaggcagat gccgtcctct atcatcaggg tgccgcgccc
     7861 ccatttgttt ttttctgaga aaaactgttt tcgtttcata accgtgccgg tctcctttgt
     7921 ttgtttcttc tcttccgttc tttccaaatc gggcttgtct catacaactc ttagtgggac
     7981 aaatcaacta tctgcgtttc tttgcataaa ctgggtaaag tgctgataga aacgaatttg
     8041 ataccgacag aaacgggatt ggagctgata tcacatgtgt ggaattgcgg gttgggtcga
     8101 ttttcaaaag cagctcgtcc aagagaaaca tattatgaac aatatgatag acactctttc
     8161 aaaacgaggg cctgatgatt caaacgtctg gggagagccc catgttttat tcggacataa
     8221 aagactttcg gtcgttgaca ttgaaggcgg ccgccagccg atggcctgca cgcatcaaga
     8281 ggagacgtac accatcattt ataatggcga gctgtataac acggaggaac tgcggaagga
     8341 gcttcaggcg aggggccacc gttttgagag gacctctgat acagaagtgc tgctgcacag
     8401 ctatattgag tggcgggagg agtgcgtgaa ccgcttgaac ggtattttcg cttttgccat
     8461 ctgggatgaa aagcgcgagc ggctgttcgg ggcaagagac cggctcggcg tcaaaccgtt
     8521 tttttataaa gaacacggct cttcctttct gtttgggtcg gaattgaaag ccatccttgc
     8581 tcatcctgat gtgaaagccc gcacagacag cggcggactt gcggaagtat tcggactcgg
     8641 gccgtccaga actccgggct gcggggtgtt taaaggaatt cacgaggtgc gtcccgctca
     8701 tgcgttcact ttctcaaagg acggtttgtc catatggcgt tattggaatg taaagagcga
     8761 aaagcataca gacagcttcg atgaaaccgc ggctcacatt cggtacttat ttcaggatgc
     8821 agtgacacgc cagctcgtat ctgacgtgcc ggtttgcacg tttttatcag gggggcttga
     8881 ttcgagcgcg ataaccgcga tagccgccgc tcattttgag aaacaaggca gagatcccct
     8941 tcatacttat tcaattgatt atgaggagaa cagcaaattt tttaaagcga gcgcctttca
     9001 gccgaatgat gacggcccgt ggatcgataa aatgacaaat gcatacggca cacagcatca
     9061 taagtgcgtg attacgcagg atcagctggt tgaacatctg gaggaatccg ttctcgtcag
     9121 agacctgccg ggcatggctg atgttgattc ctcgctatta tggttctgcc gggaaattaa
     9181 aaaagatttt gtcgtgagcc tttccggaga atgcgcggac gaaattttcg gcggatatcc
     9241 gtggtttcac accgcggcag aagaagccgg atttccttgg atgaggtcga ctgaggagag
     9301 gatcacgctc ttggatgaaa agtggcaaaa acggctgaac cttagagaat acgtgaatgc
     9361 gagatatgaa gaaaccattg cggaaacgcc gctgttagac ggtgagacgg gaacagataa
     9421 agcgagacgg cagctgttct acttaaatat gctttggttt atgacaaatc tgctcgaccg
     9481 taaagaccgc atgagcatgg gcgcaagtct tgaagtaagg gtgccgttcg ccgaccacag
     9541 acttgtggaa tacgtttgga atattccttg ggaaatgaaa atgcatggca gccgggaaaa
     9601 aggcatcttg cggaaagcgc ttgaaggact gcttcctgaa gatattttgt accgcaaaaa
     9661 aagcccttat ccgaaaacgc atcacccgaa atacacgcag ggggtcacag aatggctgaa
     9721 aacgattttg caacagaaag attccgtgct tcacaccctg cttgacagaa agaagctgga
     9781 aatgctgctg gagacagaag gttcatcttt tcaggttccg tggttcggcc agctgatgaa
     9841 aggcccgcag ctgatcgccc atcttgccca gatccataca tggtttgagg cgtaccgtat
     9901 cgatatagaa gaataacagt gccgcgaccg gtttccgctg aggatatcgg tctttttatt
     9961 gtgaaacata tggtacacta aaaaacagag gagtgatacc atgaccgaat acgaaacatg
    10021 cgcccagctt gccgaggcgc actttccttt atataaacgg actttctcaa ccctgccgcc
    10081 aaaaaacagg cgggccgcat gggcggtgct tgctttgttt cacgaagctg accggcttga
    10141 tgtgcaggaa cttgggggat ttgaacaggc ggcacaagac tttctgaacg gggcacgcgc
    10201 cgacggcttt ttgtgggaag cgctcgccga tgtgcggcag caatttgcgc ttgaagaaga
    10261 gccgttacgt gagtttatcg ccggccaaat ctctgacaga gaaaaagtaa cgtatcaaga
    10321 gtttgatgac ctgctgatgt acgcgggcca aacaggcgga gccctcggcc tgcttctgct
    10381 gccggtttgc gcgcgccgga accaagagaa actccgccat gcagccgttt cattaggagc
    10441 agccattcag ctgacccggg tgcttctggg ggtccatacg gatgagcggg cgaaaaagcg
    10501 tctcccgcgc catgtgatga agcaattcgg ctatacggaa gaagagctgg agagccatac
    10561 cgtcaacaaa gcttttatga atgtatggga gtacatcgca ttcgaggccg aggcgtattt
    10621 cgaggaggcg tctgaagcgc tggagctgtt tccgttatac tcaaggcccg ccgttaccaa
    10681 tttgctggca tattaccggt cagagctcgg tgacatgaga aaacagcttt cgcaagcata
    10741 aaaaaacgcc cggcttcata acgaagcttc gggcgtttat gcaatccctt tttgaatcca
    10801 aatccgcgac cgccatcttc tgtacataag aatgcctctg acccattcat ccgcgataaa
    10861 tgaaatccag atgcccataa gccccaatcc gaaatggatg ccgaacagat aagcgagagg
    10921 cagtccgata ccccacatgg aaatcatcgc catgtaaacg gggaattttg catctccggc
    10981 agcccgcagc gagttgatga taatgacatt aaatgaacgg ccgggctcaa gaatgatcgt
    11041 catggcgatc agcatgctcg ccgtcgcaat aatgtcaggg ctgcttgtga aaattccgat
    11101 cagctgcttt gaaaacaagg tcatgatcac ggatgtcaaa gcggcaatgc caagcgccca
    11161 gtacagactt ttcatgcagc ggtcataagc gtcgtcaaac cgtttggcgc cgatatatct
    11221 gccgatcaaa atctgtgtgc cttggctgat cgccgtcccg aacagcagga taaacatggt
    11281 gatattttgt gtataaacct ttgttgtaag cgcctgagcg cccataatgg cgataaaata
    11341 agtaacaacc atttgtgaaa tgttgtaaga cagctgttcg ccggcagacg gaatcccgat
    11401 tttcaggagt ttccgcaagt gctctttatg gacgtgaaaa atcttttgcc atgtcagacc
    11461 gagtccgatg cgttttttga cgatcacaat catcgcgatc agtccgatga tccgagcaaa
    11521 ggacgttgac atcgcaacac cggcgacgcc taacacagga aggccgagcg gcccgaaaat
    11581 gacaagaaag tttccggcaa tatttaaaat attcatcccg atcgtaacga acatcgtatc
    11641 cttcgtatga ccgtagcttt ttaaaatggc gctgaatgtc ataatcaaag cctgaatgaa
    11701 ggacagcccg ccgaccacct gcaaaaagac tttggcatcc ggcatcaatt cattggaaag
    11761 acccatcaca tgaagcagcg gaacggccgc aaaaaatatg gcggcgctga tggcgagact
    11821 gatgacaaag ttcgctccta ttgatacata agccacttcc tgcgcctctt ttttctgttt
    11881 agatcctaaa aactgtgaaa tcacaattgt cgtacccgta gcgataaagc tgaacatcac
    11941 gataattaaa tttaaaatct gattgctgac acccacggcc gccacactgt tgtcagagta
    12001 ttggctaagc ataagagtgt cggcgtttcc cataaacata tataatgaaa cctcaataaa
    12061 tatcggccaa gtcagcgcgt ataatgagag tttgtgatca gaggattgtt tgaacgcagc
    12121 ccgttttaaa atcgcttgtt tcatttcttt taaccccttt cctgacaaaa tcaacgttta
    12181 aaagtgtacc tccattttct tataataaaa agggagagaa acgaaacttc ttgcaaaaat
    12241 ccgacttaaa aaggagggcc gaaaatatgt cctttctcga gttcacagtt cctccgttcc
    12301 cggtctttat cgctgcggga gaaggagtgt tcaaaaaagg cgaaacccat gtgagacggg
    12361 tcttcccggt gtttgatctg ctgtatgtga aagaaggcgt cctctacatt acagaagacg
    12421 aaaacgcctt ttccgttgaa gcgggagaat atattctgct ttctcccggc cttgaacatt
    12481 acgggacaaa aggcagtgaa gaaacgacat cctattcgtg gcttcatttt gagggagcgg
    12541 cttatgaggt gacggaaaca accgggaaca attggtcgga gctgaggcga aaaaaaggga
    12601 gctttgaaga accgtcccgc taccgcctgt ccctgccgca aaaagggaag gtgagacgcc
    12661 cgcagtttat ggccgggcaa ttcagtgtgc tgaccgatga cagcgccgag aactccgatc
    12721 tgccgctcag aaagcagatt ctgtttgaag agctgctgct ccatcttcag aaagaagcgt
    12781 tccaaatccc gtccgcaaag gaaagagtcg catgggaggc cgcccggtac ctgcaggagc
    12841 actatcagga gaaaacaacc atcaaagcgc tctcttcggc tcttcattac aaccaagact
    12901 acgtgacccg ctgtatgcag caggtgctcg gcgtcacgcc cggccagtat acgaacaaag
    12961 tcagaatgac ggaggcgaaa cgtcttttgt ccgcaaccaa tgacaaaatg ggggcaatcg
    13021 cggacgccat cggcatggag gacccgacct atttttccaa actgtttaaa cagattgaag
    13081 gcatttcgcc gcttgaatac cgcaaattcg taagccggaa aacggactga cctaaaacca
    13141 gagaacaaaa gagggatcag taagcatgaa aatgacaatt tacgatgtgg ccgaaaaagc
    13201 gggcgtctcc atctcgacgg tctcgcgggt catcaacaat acggggagga tcagtgacaa
    13261 aacccgccgg atggtgctcc gtgtcatgga ggagatggac tatcatccga atgttcacgc
    13321 atccgctttg acgggcaaaa agacgaatat gatcggcctg atcaccccgg atatttcaaa
    13381 cccgtttttc ggggaactgg cgaaaagcat tgaagacagc gccggtgcac tgggatttca
    13441 tatcattatc tgcagcaccg attatcagcc tgaaaaagaa acgaagtatt tttcgatgct
    13501 gcggcagaag caggcggacg gcattatttt cgcgacggga cttgatcatg atgacagcgt
    13561 cacagcgctt gatgatatgg tgaaatcggg catcccgctt gcgatgatta cgcaggataa
    13621 accgctcgcg ccgatggacg tcgtcattat cgatgacttt ctcggcggct atacggcggc
    13681 tgagcatctc atatctttag gccataaaag aattgcctgt atcgtcggca acggttcgac
    13741 gacgggtgaa agagacagaa tcaaaggctt tcgaaaagcg atgcgggaag cggggatgac
    13801 actagatgaa tcgctgatca taccgacgga atattcgctg gaaagcggaa aacaggcagc
    13861 gggcgagctg tttgacagag accttccgac cgccgttttc gcctttaatg acgtcttgtc
    13921 atgcgcggcg atacaggcgg cgcgctcccg gggcattcgg gtgccggaag acttgtcggt
    13981 catcggcttt gacaatacca ttctcgctga aatgacggca ccgccgctca cgacgatttc
    14041 tcagcccata cgcgaaatgg ggcggcgtgt cgttgaactt ctcattgatg agattcaagg
    14101 gaagaaaaaa acaaaaagca aaatcatttt atctccggaa ctcgtcatca ggcattctac
    14161 ggcaccggca aaaacgcgcc ctcagcgata aggcgcgttt ttttctatga aaaacattgt
    14221 caaacgagcg aaaagcattg taaaattaaa acagctttga gaaagcgctt gcgcaaactg
    14281 cggattgcaa gaaaagaaag caaacagctt gggttataaa taaagcgctt tcaaaatgat
    14341 gatttctgtt taataaggga aaccgcttgc gcaattgcgg catgcggcct caagaaaaaa
    14401 ggagcggtga tagatgacag atcaagtcag atgtgcggtg ctgggattag gacgattagg
    14461 gtattttcat gcgaagcatt tagtcagcga agtgcgggga gccgagcttg cggccgtctg
    14521 tgacccgatg aagggaaagg cggaagcgtg tgcgaaagaa ttaggaatcg ccaaatggac
    14581 ggagaatccg tatgacctgt tggaagatca cacgattgac gccgtcatca ttgtcacacc
    14641 gacaagcaca catgcggaaa tgatcatgaa ggctgctgaa aacggcaagc acatctttgt
    14701 tgaaaagccg ctcaccctga gtcttgagga atctaaagaa gtcatgaaaa aaatcgaaga
    14761 aacgggcgtc atctgccagg tcggttttat gaggcggttt gatccggcat acgccgacgc
    14821 gaaaagaaga atcgacgccg gggaaatcgg caggcccatt tattataaag gatttacaag
    14881 agatcaaggc gcaccgcccg cggaatttat caaacatagc ggagggcttt tcattgactg
    14941 ttcgattcat gattacgaca tcgcgagata tctcatgaat gccgaagata cgtccgtctg
    15001 cgggcacggg agaattttaa agcacccgtt catggaggag tgcggcgacg ttgatcaggc
    15061 attaacgtat cttgaatttg attcgggcgc ggccggcgat gtggaggcaa gccgaaattc
    15121 tccgtacggg catgatatcc gcgccgaaat tatcgggacg gcgggaagca tcttggtcgg
    15181 aacgctgcgg aaaagccatg tcaccatttt aacggagtca ggcagcagct acgaaattat
    15241 tccggatttt caagcccgct ttaaagacgc ttaccgtctg gagcttgagc actttgccga
    15301 atgtgtgaaa aaaggggaaa cgccgattgt gacagacgtc gatgccacga ttaacttaga
    15361 aatcgggatc gccgcgacgg aatcgtttaa aaccggaagg cctgtaaagc ttaccccggg
    15421 cgccttcggc tatgccggac tatgatagat tcgaagtgaa aaagtggctg ggacaaaact
    15481 agcttcaaat aatgagaaag gtgaatttgg gggtactcaa attcatcttt cttt
//
