LOCUS       NZ_JAIONG010000001     26354 bp    DNA     linear   CON 22-NOV-2024
DEFINITION  Bacillus amyloliquefaciens strain SN_Endo51 sequence01, whole genome
            shotgun sequence.
ACCESSION   NZ_JAIONG010000001
VERSION     NZ_JAIONG010000001.1
KEYWORDS    WGS; RefSeq.
SOURCE      Bacillus amyloliquefaciens
  ORGANISM  Bacillus amyloliquefaciens
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Bacillaceae;
            Bacillus; Bacillus amyloliquefaciens group.
REFERENCE   1  (bases 1 to 386901)
  AUTHORS   Roy,M. and Dutta,T.K.
  TITLE     Community profile and biosynthetic gene analysis from end to end
            microbiomes of the medicinal mangrove Suaeda monoica Forssk. ex J.F.
            Gmel of Indian Sundarbans
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 386901)
  AUTHORS   Roy,M. and Dutta,T.K.
  TITLE     Direct Submission
  JOURNAL   Submitted (03-SEP-2021) Microbiology, Bose Institute, P-1/12, CIT
            Road Scheme VIIM, Kolkata, West Bengal 700054, India
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 30-MAY-2021
            Assembly Method                   :: SPAdes v. 25.05.2021
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 10.0x
            Sequencing Technology             :: Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_020179775.1-RS_2024_11_20
            Annotation Date                   :: 11/20/2024 08:35:12
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,314
            CDSs (total)                      :: 4,259
            Genes (coding)                    :: 4,097
            CDSs (with protein)               :: 4,097
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 46
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 162
            CDSs (without protein)            :: 162
            Pseudo Genes (ambiguous residues) :: 0 of 162
            Pseudo Genes (frameshifted)       :: 91 of 162
            Pseudo Genes (incomplete)         :: 72 of 162
            Pseudo Genes (internal stop)      :: 30 of 162
            Pseudo Genes (multiple problems)  :: 28 of 162
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 19:57:53
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 250916
            Orig. end                         :: 277270
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JAIONG010000001.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..26354
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-ii"
                     /region_number="2"
                     /rules="cds(LANC_like and DUF4135)"
                     /tool="antismash"
     cand_cluster    1..26354
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..26354
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:16354](-)"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..16354)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     gene            complement(159..1298)
                     /gene="opuCA"
                     /locus_tag="K8B35_RS01315"
     CDS             complement(159..1298)
                     /codon_start=1
                     /gene="opuCA"
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013353644.1"
                     /locus_tag="K8B35_RS01315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="osmoprotectant ABC transporter ATP-binding
                     protein OpuCA"
                     /protein_id="WP_003151651.1"
                     /transl_table=11
                     /translation="MLRLENVSKVYKGGKKAVNSIDLNIEKGEFICFIGPSGCGKTTTM
                     KMINRLIEPSSGKIFIDGENIMEQDPVELRRKIGYVIQQIGLFPHMTIQQNISLVPKLL
                     KWPEQKRKERARELLKLVDMGPEYLDRYPHELSGGQQQRIGVLRALAAEPPLILMDEPF
                     GALDPITRDSLQEEFKKLQRTLNKTIVFVTHDMDEAIKLADRIVILKAGEIVQAGTPDD
                     ILRNPANEFVEEFIGKERLLQSRPDIERVEQMMNKKPVTVTADKTLSQAIQVMREHRVD
                     SLLVVDDLNVLQGYVDVEIIDQNRKKASLVGDVLRSDLYTVEQGTLLRDTVRKILKRGM
                     KYVPVVDEQRHLVGIVTRASLVDIVYDSIWGEEDQLVTG"
     misc_feature    1325..1339
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 23.56"
                     /tool="antismash"
     CDS             1387..1533
                     /gene="allorf_252303_252449"
                     /locus_tag="allorf_252303_252449"
                     /protein_id="allorf_252303_252449"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MLKLYTIYVFFHVIPLTMRMFLQSLPIARISCRIIFFINCKKYDI
                     LSA"
     CDS_motif       1387..1470
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MLKLYTIYVFFHVIPLTMRMFLQSLPIA"
                     /locus_tag="allorf_252303_252449_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       1471..1533
                     /prepeptide="core"
                     /locus_tag="allorf_252303_252449_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.60"
                     /molecular_weight="2367.9"
                     /monoisotopic_mass="2366.3"
                     /core_sequence="RISCRIIFFINCKKYDILSA"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MLKLYTIYVFFHVIPLTMRMFLQSLPIA"
                     /leader_location="[1386:1470](+)"
     misc_feature    1393..1411
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: medium, score: 29.41"
                     /tool="antismash"
     CDS             complement(1419..1502)
                     /gene="allorf_252335_252418"
                     /locus_tag="allorf_252335_252418"
                     /protein_id="allorf_252335_252418"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MMKKMMRQDMRAIGSDCKNIRIVSGIT"
     CDS_motif       complement(1458..1502)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MMKKMMRQDMRAIGS"
                     /locus_tag="allorf_252335_252418_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(1419..1457)
                     /prepeptide="core"
                     /locus_tag="allorf_252335_252418_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.80"
                     /molecular_weight="1282.5"
                     /monoisotopic_mass="1281.7"
                     /core_sequence="DCKNIRIVSGIT"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MMKKMMRQDMRAIGS"
                     /leader_location="[1457:1502](-)"
                     /alternative_weights="1300.5"
     gene            1559..2116
                     /locus_tag="K8B35_RS01320"
     CDS             1559..2116
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014418904.1"
                     /locus_tag="K8B35_RS01320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="GbsR/MarR family transcriptional regulator"
                     /protein_id="WP_159354595.1"
                     /transl_table=11
                     /translation="MEKNALDIIGHAEEHLIERIAENMHTFGMPATLGRVLGIIYMNRK
                     PMTLNELSEATGMSKTRMSQVVREMTDANLAEKVFEKGVRKDLYDVERDYYQTFISLFT
                     ANWTKAVSKNKMLYKKLNRELTELLESENLSPDIEEKARQLLDELKDWLHYYDWLSRLI
                     EFFESEEVFQHVPKIEKSSTRR"
     gene            complement(2137..2769)
                     /locus_tag="K8B35_RS01325"
     CDS             complement(2137..2769)
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014471043.1"
                     /locus_tag="K8B35_RS01325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="NAAT family transporter"
                     /protein_id="WP_159354596.1"
                     /transl_table=11
                     /translation="MFSFIIHVFISLFAVSNPIGNVPIFLSLTEGYSEKERTAIARKAS
                     VLSFIILAAFLIFGHLIFKLFDINIHALRIAGGIFIFGIAYNLLNAKKSHVQSLHHEEK
                     GENKEKADISVTPLSIPIIAGPGTIATVMSLSAGHGGIIHYISVLIGIAAVIAMTFIFF
                     HYSSFISNKLGKTEMNVITRLMGLILAVVAIGMIGAGLKGMFPILVS"
     gene            3205..3915
                     /locus_tag="K8B35_RS01330"
     CDS             3205..3915
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007409971.1"
                     /locus_tag="K8B35_RS01330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_060562556.1"
                     /transl_table=11
                     /translation="MYCSQCGHHTDGGKFCEKCGAPQPGQGGAGQTQGQAAQAGAAAKQ
                     ASKQFALFVLDVLKRPYQTCKTTGGEQLVSSIINMVLFCLVTPIMFYILLTDGFRDVSF
                     TAIVVKPALTFALCVFCLYLLIFIALKAGGAQVSFKDSLSRFGAFLIPFTAILLLALIF
                     MLLHTTVCFTILAVGLLGAAFAVPPLMLASYQHQLTTKADIIYSVIVIYLIICVTFQFT
                     IKHYIKELMNYFFF"
     gene            complement(3957..5735)
                     /locus_tag="K8B35_RS01335"
     CDS             complement(3957..5735)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014305844.1"
                     /locus_tag="K8B35_RS01335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="WP_159354597.1"
                     /transl_table=11
                     /translation="MFFCKYCGQQNNEEAHFCKECGKPIGKGSRLERQAAESASQPRKP
                     IPKKTLFLWGGIAAALILLIAAYKTGAWLTSEKRLTDQFEQAVHDGDTKKLAALLTPSD
                     KKLKLNETNVKPLLAYAKKHDELLASLRGNSSEKDAVYVKKEGKTLLLFDHYELKVDPV
                     YFRVTSNYKGADLYINSEKTGTVKKADETQIFGPYAPGVYTAEAKLKNETVDVVKKQEA
                     EAAGSRNVEFDLPLDAEDVTFTPADSFKSAKGDLLINGKSVHKDPFTSVTYGPLLTDGS
                     MTAAVEADFPWGKMKTADVPINSTDVDLTLIPDQDTQQTIMDTIVKTTKQYTKAMADGN
                     TDQMTEAGSAWKEQTKEVVSGMKSSGTFLKDQYKETSFDLDSFAISQENGRWQVTVTGK
                     ELHESAYFDGNTKPDMEEAEPSFHYVLSYDTKHKKWVFEKADPASDSSGTNVKKIKNDQ
                     PKTYTSAWASSKGNTASGSVTNEQVTSFMTDYLTNQSSAVSLNNFAIMAGNLEEGSPLY
                     ADQQKLVKKLHSEGTTEVFNEVNVKSFSQKGSHLTIHTYEEFYITKAGGSPKLRTYNWT
                     YGGVVKDGRIYLTSIQ"
     misc_feature    complement(5819..5832)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.2"
                     /tool="antismash"
     gene            5867..6328
                     /locus_tag="K8B35_RS01340"
     CDS             5867..6328
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015714718.1"
                     /locus_tag="K8B35_RS01340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="N-acetyltransferase"
                     /protein_id="WP_159354598.1"
                     /transl_table=11
                     /translation="MQKLSIRKAAEPDEALYELLLLADPSKEIVDDYLVRGECYTAWTS
                     DELAGVYVLLQTRPKTIEIVNIAVKESLQNKGFGKQLVRDAIEKARQSGADTIEIGTGN
                     SSIHQLSLYQKCGFRIQAVDHDFFIRHYDEDIFENGIQCRDMIRLYLDL"
     gene            complement(6388..7328)
                     /locus_tag="K8B35_RS01345"
                     /pseudo=""
     CDS             complement(6388..7328)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611387.1"
                     /locus_tag="K8B35_RS01345"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="IS3 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MRVSDPVEVKQKV"
     misc_feature    complement(7550..7563)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 23.22"
                     /tool="antismash"
     gene            complement(7645..7815)
                     /locus_tag="K8B35_RS01350"
     CDS             complement(7645..7815)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="K8B35_RS01350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_155238646.1"
                     /transl_table=11
                     /translation="MKNYKGDGAVFLVIGFCLGLFLGVVFDILPYGLSIGILIGSLIDL
                     YFYARYKNNNK"
     gene            complement(7839..10004)
                     /locus_tag="K8B35_RS01355"
     CDS             complement(7839..10004)
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012869.5"
                     /locus_tag="K8B35_RS01355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="peptidase domain-containing ABC transporter"
                     /protein_id="WP_021495216.1"
                     /sec_met_domain="Peptidase_C39 (E-value: 3.7e-38, bitscore:
                     124.9, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIVKKKKRVPIVKQLQQTECGLCCCAMLIRFYNSNETLFELRSFL
                     EAGRDGLTIKQLKNLLVHKGFKADIYKSTILGLKKINVPFIAYWNNEHFIVVEKIKENY
                     YYIIDPANGRRKLTEEEFKKGFSSYILYAVPSESFTPNKRKDKNVWFGVLKNITNYKLL
                     FSIIVFLSLISYLLTLYVPILVQKLIDTSIEYNNLNSISNIVWITFLISILYGMFVLFR
                     GLKMISLNIFLSKNLVVDTFAHLLKLPFKFFDLRSPGDLLFRLNSMNGFRELLSTQLIS
                     GLIDLGAVVFILAYMFFKSIPLTLITILIFAINTIFMFLTRPAVAQAIDDEVAEQSKSQ
                     AIQIESIFSIAAIKISGMENEIFSTWNNSFNEVIKRFKKRSILQNVVNTVTQVFQTIAP
                     LVILILELLLFFDNKFTMGEVIAYHSLSVTFFGLTTALFGTYTQFILATSYLERVKDIT
                     ETECEKNIENAVNLKLRGNVKLENVSFSYTKHSPKVLKNISLEIREGQKIAIVGSSGSG
                     KSTLSKLIMGLYDPTEGQICFDSIPLEKLDRKQLYKQMGIVPQDITLFNSSILKNITLN
                     NKNISIEKVRKVAKAAQIDKEIESMPMKYNTPISEMGMNLSGGQRQRIVLARALLNDPK
                     ILILDEATSSLDLVNETLISKYLSEMGCTRVVIAHRLSTIMDSDFIIVLDKGEVVEVGK
                     HEELIALEGVYSNLYRSQTKKQKTYSS"
     gene            complement(10001..12940)
                     /locus_tag="K8B35_RS01360"
     CDS             complement(10001..12940)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR03897.1"
                     /locus_tag="K8B35_RS01360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="type 2 lanthipeptide synthetase LanM family
                     protein"
                     /protein_id="WP_224988018.1"
                     /sec_met_domain="DUF4135 (E-value: 1.3e-88, bitscore:
                     292.2, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 1.7e-62, bitscore:
                     205.7, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDISYENNNFIRDAVINFSSPTNEVEKLRIKNKDYFGNFYTFFLD
                     FYQQKLVNTLENASKENNLKLNKHKIISSALEAFSQELIQLCIRTLIVDINERKENGLL
                     EGKDSRLRYKNYNNLIFKSEYVAGILNKYPVLTYLISSRISNKILYLKEVLENLRKNRQ
                     DIYRELKIEFDEVSNIYFSSGDTHNGGKNVLIIETNQGKIVYKPHSLSPDILFNSIVDY
                     VNNSDKILKKIYKIRTLNYKDYGYQEFIDYKECETSEKLNFYFYRVGVSLSIFHIIGCD
                     DLHHENLIAHGEYPVVIDLETLIKNNSMYKPRNNNLIDNFHEDINYSVLGTMLLPLNLQ
                     TSIFDFDLGGISNDENQTSEIWKSYIIDFEGTDEIQLTKKSVIMNSTQNRAAYNGKAAD
                     PKDYIEEILKGFTDCYNFVLENKSGFYDLVKTVGSSNLEVRQVLRATSIYARFLEASTH
                     PNYLSSFEERKELFKKINIAEGVTDKFSKKNLNELESLMCNDVPYFSTMYNSLDLICNK
                     STSIVNFFRECLLDVVLNKIKSISKTSLKKQQYYIRMSLTTTIKDSWKRTNKHNKKYRP
                     KLFGNNNKNYLECATEIGDLFLETAIWNNDRSKCTWVTPIISENNKVKLGPLNFDLYEG
                     GGVILFLALLGKETGNKEYFDLAFAGMRGIEELFLSDDKMDGRLSLFTGIGSLAYIYYH
                     LYTYTNDYKYYEKFKKYINKINEMNISGDIPLDIVGGVSSLIVFLLNLYKETKLDILNS
                     VCCKLGNTLYQCLEKNGKYNYLTGLSHGYSGFTLALCYLGHITKDEKYTTLGKELLKRE
                     NKFFDLNTSNWKDLREGEGNSDPVYWCHGAGGIALSRAFLKNLLKNKENVVDKEVDKDL
                     NCAISKLLSDGFKKTTDHSLCHGIFGNIDILLKLSELLNDIDLQEVAFKEAQNAINYIR
                     NKGFIPGLQDHFELNTFMLGLGGVGYSLLRLHNPVNPSLLAMEVRSYNE"
     gene            complement(13009..13218)
                     /locus_tag="K8B35_RS01365"
     CDS             complement(13009..13218)
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF038161.1"
                     /locus_tag="K8B35_RS01365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="class II lanthipeptide, LchA2/BrtA2 family"
                     /protein_id="WP_095270659.1"
                     /transl_table=11
                     /translation="MKKDMVKKASGFIEEDELISLANGDNATGGATPATVVLTATIGLT
                     GTTFTVTLSAASCPTSACTKQCNK"
     CDS_motif       complement(13129..13218)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MKKDMVKKASGFIEEDELISLANGDNATGG"
                     /locus_tag="K8B35_RS01365_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(13009..13128)
                     /prepeptide="core"
                     /locus_tag="K8B35_RS01365_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-5.10"
                     /molecular_weight="3579.1"
                     /monoisotopic_mass="3576.9"
                     /core_sequence="ATPATVVLTATIGLTGTTFTVTLSAASCPTSACTKQCNK"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MKKDMVKKASGFIEEDELISLANGDNATGG"
                     /leader_location="[13128:13218](-)"
                     /alternative_weights="3597.1"
                     /alternative_weights="3615.2"
                     /alternative_weights="3633.2"
                     /alternative_weights="3651.2"
                     /alternative_weights="3669.2"
                     /alternative_weights="3687.2"
                     /alternative_weights="3705.3"
                     /alternative_weights="3723.3"
                     /alternative_weights="3741.3"
                     /alternative_weights="3759.3"
                     /alternative_weights="3777.3"
     gene            complement(13268..16354)
                     /locus_tag="K8B35_RS01370"
     CDS             complement(13268..16354)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR03897.1"
                     /locus_tag="K8B35_RS01370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="type 2 lanthipeptide synthetase LanM family
                     protein"
                     /protein_id="WP_159354600.1"
                     /sec_met_domain="DUF4135 (E-value: 2.6e-98, bitscore:
                     324.2, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 1e-68, bitscore:
                     226.2, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTNKYNLQYWMKMFPEVNNKDELQKIFLNVSGKTIQSLIRDDTN
                     IEQNKSIIDIDRVLDHKKSDFLVRNSEEFLEHNPFFHFFSPFLNCKIEEFLVKVRIEDA
                     VDNEDEFVKKVIKHIMDLMFEKAFRVLVLEVNIARLEGNLEGTTPEERLNHFLVVSLND
                     ESFLKSVYKEYEVLTSLLCVTIDDYFTYVMEIIKNTKREISSLNSKFNSDNDLGAITNI
                     TTGLGDTHQKGKSVSTIYFKSGKKIIYKPRDLTLEQGFQEVLYWLGEKNIPGILNFKRV
                     QIHTVNDSGWMEYIDYKSCFNKNEANDFYTRSGNLLCLLYLLNAVDFHHENLIAHGSFP
                     VLVDLESLFHARLKVDQIDKKSAVVKATELVDNSVQSISLLPTKISKRVGDKDISLDIG
                     GLAAYKEQLSPHKSLVIENAGTDTIKILRKNTFIKPQLNNPSIKTGSYLYSENYTGQIK
                     DGFASLYSWVMLNKDEFWDKISQTFKETNSRFIFRPTYLYTQLLRISSHPDFMRDTYRR
                     KIILHRIGIDYIQEYKDILNSEYKDLLTGDVPFFRSSIEHEHLIDSRGKRIYSILEEPP
                     IKTVKQKIFNLSKEDLKRQIDFIEMSYISNEKRLKEVTDIKFSKAASLNKIKSENWIDE
                     ATQIGEFIVENSVCGINKKQKDRMWIGPSLEGIEEDIWNANVLGFDIYNGNSGIALFLG
                     YLGEILNRKDFKQAAIETMRPIQKFISEIKEDHPYLIGAFQGISGYFYTLNKLSNLFGD
                     SELRKTSLENIGVLSKLGKFDKVYDLIGGSLGSLAVMLSIIPDITEENNKKEILKISHT
                     HCEHILSVAKNFEEQISWPGKFSAAYSGFSHGNSGFIAYLYKYFKLTNDEKLLEVIQRA
                     LRFERRLYSEDHNNWYTTENKDKLANGWCHGAPGILLSKLILKDNGFEDEYIEKEISTA
                     IDSSIRNGIGNNPTYCHGDLGVLSILNYASDLTNNINLKNRCLRTYQDLFENVLTKKWR
                     KRDLVCTRSYSLMIGLSGIGYSMIKNYAPEIVPNFLWLE"
     gene            complement(16427..16657)
                     /locus_tag="K8B35_RS01375"
     CDS             complement(16427..16657)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) mature_ha"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF000539.0"
                     /locus_tag="K8B35_RS01375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="plantaricin C family lantibiotic"
                     /protein_id="WP_021495220.1"
                     /sec_met_domain="mature_ha (E-value: 4.9e-08, bitscore:
                     27.2, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKTKILKTPELKVTKDLNLIDPCGDVLEEIKEHEVSGAFNTWNT
                     TTTSLGGILVSEVLGNKGKVCTGTKECQGTC"
     CDS_motif       complement(16541..16657)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MKKTKILKTPELKVTKDLNLIDPCGDVLEEIKEHEVSGA"
                     /locus_tag="K8B35_RS01375_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(16427..16540)
                     /prepeptide="core"
                     /locus_tag="K8B35_RS01375_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-3.20"
                     /molecular_weight="3669.1"
                     /monoisotopic_mass="3666.9"
                     /core_sequence="FNTWNTTTTSLGGILVSEVLGNKGKVCTGTKECQGTC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MKKTKILKTPELKVTKDLNLIDPCGDVLEEIKEHEVSGA"
                     /leader_location="[16540:16657](-)"
                     /alternative_weights="3687.1"
                     /alternative_weights="3705.2"
                     /alternative_weights="3723.2"
                     /alternative_weights="3741.2"
                     /alternative_weights="3759.2"
                     /alternative_weights="3777.2"
                     /alternative_weights="3795.3"
     misc_feature    16918..16931
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: strong, score: 24.53"
                     /tool="antismash"
     misc_feature    16944..16956
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 19.83"
                     /tool="antismash"
     misc_feature    17527..17538
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 18.71"
                     /tool="antismash"
     misc_feature    complement(17719..17734)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 21.73"
                     /tool="antismash"
     gene            complement(18044..19336)
                     /gene="eno"
                     /locus_tag="K8B35_RS01380"
     CDS             complement(18044..19336)
                     /EC_number="4.2.1.11"
                     /GO_component="GO:0000015 - phosphopyruvate hydratase
                     complex [Evidence IEA]"
                     /GO_function="GO:0000287 - magnesium ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0004634 - phosphopyruvate hydratase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="eno"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391270.1"
                     /locus_tag="K8B35_RS01380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="phosphopyruvate hydratase"
                     /protein_id="WP_007409956.1"
                     /transl_table=11
                     /translation="MPYIVDVYAREVLDSRGNPTVEVEVYTETGAFGRALVPSGASTGE
                     YEAVELRDGDKDRYLGKGVLTAVNNVNEIISPELLGFDVTEQNAIDQLLIELDGTENKG
                     KLGANAILGVSMACARAAADFLQIPLYQYLGGFNSKTLPVPMMNIVNGGEHADNNVDIQ
                     EFMIMPVGAPNFREALRMGAQIFHSLKSVLSAKGMNTAVGDEGGFAPNLGSNEEALQTI
                     VEAIEKAGFKPGEEVKLAMDAASSEFYNKEDGKYHLSGEGVVKTSAEMVDWYEEMVSKY
                     PIISIEDGLDENDWEGHKLLTERLGKKVQLVGDDLFVTNTKKLAEGIKNGVGNSILIKV
                     NQIGTLTETFDAIEMAKRAGYTAVISHRSGETEDSTIADIAVATNAGQIKTGAPSRTDR
                     VAKYNQLLRIEDQLAETAQYHGINSFYNLNK"
     gene            complement(19364..20899)
                     /gene="gpmI"
                     /locus_tag="K8B35_RS01385"
     CDS             complement(19364..20899)
                     /EC_number="5.4.2.12"
                     /codon_start=1
                     /gene="gpmI"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391271.1"
                     /locus_tag="K8B35_RS01385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="2,3-bisphosphoglycerate-independent
                     phosphoglycerate mutase"
                     /protein_id="WP_159354601.1"
                     /transl_table=11
                     /translation="MSKKPAALIILDGFGLRNETVGNAVAQAKKPNFDRYWNQYPHQTL
                     TASGEAVGLPEGQMGNSEVGHLNIGAGRIVYQSLTRVNVAIREGEFERNQTFLDAIKNA
                     KDNDKALHLFGLLSDGGVHSHINHLFALLKLAKSEGLTKVYIHGFLDGRDVGPQTAKTY
                     IQQLNEQIEEIGVGEIASISGRYYSMDRDKRWDRVEKAYRAMAYGEGPSYRNAMDVVDD
                     SYANGIHDEFVIPSVITKENGEPVAKIHDGDSVIFYNFRPDRAIQISNTFTNKDFRDFD
                     RGENHPKNLYFVCLTHFSESVDGYVAFKPVNLDNTVGEVLAQHGLKQLRIAETEKYPHV
                     TFFMSGGREEEFPGEERILINSPKVATYDLKPEMSAYEVKDALVKEIAADKHDAIILNF
                     ANPDMVGHSGMVEPTIKAIEAVDECLGEVVDAIIAKGGHAIITADHGNADILITETGEP
                     HTAHTTNPVPVIVTKEGVTLREGGILGDLAPTLLDLLGVEKPKEMTGTSLIQK"
     gene            complement(20892..21653)
                     /gene="tpiA"
                     /locus_tag="K8B35_RS01390"
     CDS             complement(20892..21653)
                     /EC_number="5.3.1.1"
                     /GO_function="GO:0004807 - triose-phosphate isomerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="tpiA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391272.1"
                     /locus_tag="K8B35_RS01390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="triose-phosphate isomerase"
                     /protein_id="WP_017418891.1"
                     /transl_table=11
                     /translation="MRKPIIAGNWKMNKTLGEAVSFVEEVKSSIPAADKAEAVVCAPAL
                     FLEKLTSAVKGTDLKVGAQNMHFEENGAFTGEISPVALKDLGVDYCVIGHSERREMFAE
                     TDETVNKKAHAAFKHGIVPIICVGETLEEREAGKTNGLVADQVKKGLAGLSEEQVAASV
                     IAYEPIWAIGTGKSSTAKDANDVCAHIRKVVAESFSQETADKLRIQYGGSVKPANIKEY
                     MAESDIDGALVGGASLEPQSFVQLLEEGQYE"
     gene            complement(21679..22863)
                     /locus_tag="K8B35_RS01395"
     CDS             complement(21679..22863)
                     /EC_number="2.7.2.3"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391273.1"
                     /locus_tag="K8B35_RS01395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="phosphoglycerate kinase"
                     /protein_id="WP_159354602.1"
                     /transl_table=11
                     /translation="MNKKTVKDIDVKGKVVFCRVDFNVPMKDGEVTDDTRIRAALPTIK
                     HLADQGAKVLLASHLGRPKGETVEELRLTPVAARLGELLAKEVKKADEAYGDAVKAQIS
                     DMKDGDVLVLENVRFYPGEEKNDPELAKAFAELADVYVNDAFGAAHRAHASTAGIAEHL
                     PAVAGFLMEKELDVLGKAVTNPERPFTAIIGGAKVKDKIGVIESLLDKVDNLIIGGGLA
                     YTFVKALGYEVGKSLLEEDKIELAKSFMDRAKEKGVTFYMPEDVLVADDFSNDANVQIV
                     PISEIPSDLEAIDIGTKTRETYAEVIKNSKLVVWNGPMGVFEIDLFAQGTKAVAEALAE
                     ANDTYSVIGGGDSAAAVEKFGLADKMSHISTGGGASLEFMEGKELPGVAALNDK"
     CDS             complement(22928..23158)
                     /gene="allorf_273844_274074"
                     /locus_tag="allorf_273844_274074"
                     /protein_id="allorf_273844_274074"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MVLSDRNAIMKADKGRGRTPFPFFHENRLSESAGLLQNVRVLKFP
                     RHFRFLSRLPWLRRRSAPCPEAAICPAAEAS"
     CDS_motif       complement(23054..23158)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MVLSDRNAIMKADKGRGRTPFPFFHENRLSESAGL"
                     /locus_tag="allorf_273844_274074_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(22928..23053)
                     /prepeptide="core"
                     /locus_tag="allorf_273844_274074_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-5.70"
                     /molecular_weight="4707.5"
                     /monoisotopic_mass="4704.6"
                     /core_sequence="LQNVRVLKFPRHFRFLSRLPWLRRRSAPCPEAAICPAAEAS"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MVLSDRNAIMKADKGRGRTPFPFFHENRLSESAGL"
                     /leader_location="[23053:23158](-)"
                     /alternative_weights="4725.5"
     misc_feature    complement(23106..23115)
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 16.98"
                     /tool="antismash"
     gene            complement(23185..24192)
                     /gene="gap"
                     /locus_tag="K8B35_RS01400"
     CDS             complement(23185..24192)
                     /GO_function="GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA]"
                     /GO_function="GO:0050661 - NADP binding [Evidence IEA]"
                     /GO_function="GO:0051287 - NAD binding [Evidence IEA]"
                     /GO_process="GO:0006006 - glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="gap"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391274.1"
                     /locus_tag="K8B35_RS01400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="WP_159354603.1"
                     /transl_table=11
                     /translation="MAVKVGINGFGRIGRNVFRAALNNPEVEVVAVNDLTDANMLAHLL
                     QYDSVHGKLDAEVSVDGNNLVVNGKTIEVSAERDPAKLSWGKQGVEIVVESTGFFTKRA
                     DAAKHLEAGAKKVIISAPANEEDITIVMGVNEDKYDAANHDVISNASCTTNCLAPFAKV
                     LNDKFGIKRGMMTTVHSYTNDQQILDLPHKDYRRARAAAENIIPTSTGAAKAVSLVLPE
                     LKGKLNGGAMRVPTPNVSLVDLVAELNQEVTAEEVNAALKEAAEGDLKGILGYSEEPLV
                     SGDYNGNANSSTIDALSTMVMEGSMVKVISWYDNESGYSNRVVDLAAYIAKQGL"
     gene            complement(24239..25261)
                     /gene="cggR"
                     /locus_tag="K8B35_RS01405"
     CDS             complement(24239..25261)
                     /codon_start=1
                     /gene="cggR"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391275.1"
                     /locus_tag="K8B35_RS01405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="gapA transcriptional regulator CggR"
                     /protein_id="WP_009968188.1"
                     /transl_table=11
                     /translation="MNQLIQAQKKLLPDLLLVMQKRFEILQYIRLTEPIGRRSLSASLG
                     ISERVLRGEVQFLKEQNLVDIKTNGMTLTEEGYELLSVLEDTMKDVLGLTLLEKTLKER
                     LNLKDAIIVSGDSDQSPWVKKEMGRAAVACMKKRFSGKNIVAVTGGTTIEAVAEMMTPD
                     SKNRELLFVPARGGLGEDVKNQANTICAHMAEKASGTYRLLFVPGQLSQGAYSSIIEEP
                     SVKEVLNTIKSASMLVHGIGEAKTMAQRRNTPLEDLKKIDDNDAVTEAFGYYFNADGEV
                     VHKVHSVGMQLDDIDAIPDIIAVAGGSSKAEAIEAYFKKPRNTVLVTDEGAAKKLLRDE
                     "
     misc_feature    25356..25369
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 23.01"
                     /tool="antismash"
     misc_feature    complement(25448..25466)
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 23.66"
                     /tool="antismash"
     misc_feature    complement(25576..25590)
                     /note="TFBS match to OsdR, Development and stress
                     management regulator, confidence: weak, score: 19.59"
                     /tool="antismash"
     misc_feature    complement(25869..25885)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 20.87"
                     /tool="antismash"
     misc_feature    26338..26353
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 22.14"
                     /tool="antismash"
ORIGIN
        1 tctcgtcagc gccactccga gcggaacggc gacgacaatg cctaatatga cggcgatgat
       61 cgaaatgtat aaatgctccc acgttttata taacagttct ccgccgttcg tctgcaaaaa
      121 cttgatcatt tcattcattg taagcgttcc tccccttgtc agcctgtcac cagctggtct
      181 tcctcgcccc agattgaatc gtaaacgatg tcgacaaggc tcgctctcgt gacaattccg
      241 actaaatgcc tttgttcatc aacgacgggt acatatttca ttccgcgctt taaaattttg
      301 cgtacggtat cacgcagcag tgtcccctgc tcgaccgtat acagatcaga gcggagcacg
      361 tcgccgacga gactcgcttt tttccggttc tgatcaatga tttcgacatc cacatatcct
      421 tgcagcacat tcaggtcatc aacgacaagc agggaatcga cacggtgttc ccgcatcacc
      481 tgtatcgcct gcgaaagcgt tttgtccgcc gtaacggtga caggcttttt gttcatcatc
      541 tgctcgacgc gttcaatatc cggtcttgat tgcaataacc gttctttgcc gataaattct
      601 tcgacaaact cattagccgg attccggaga atgtcatcag gagtgccggc ctgaacgatc
      661 tctcccgctt ttaaaatgac gatccggtca gccagcttaa tagcttcatc catatcgtgt
      721 gttacaaaca caatcgtttt attcaatgtt ctttgcagtt ttttgaattc ttcttgaagg
      781 gaatcccgcg taatcggatc aagcgctccg aacggttcat ccatgagaat aagaggcggt
      841 tccgctgcaa gggcgcgcag cacgccgatt ctctgctgct gtccgccgct cagctcgtga
      901 ggatagcggt ctaaatattc cgggcccata tcgacgagct tcaaaagctc ccgcgcccgt
      961 tccttccgct tttgttccgg ccatttcagc agtttcggca cgagggaaat gttctgctga
     1021 atggtcatat gagggaaaag tccgatctgc tgaatgacgt agccgatttt ccgtctcagc
     1081 tccaccgggt cctgctccat aatgttttcg ccatcgataa aaatctttcc ggatgacggc
     1141 tcaatcagtc tgttaatcat tttcatcgtc gtcgtttttc cgcagccgct cggcccgata
     1201 aaacaaataa actcgccttt ttcgatattt aaatcaatgc tgttgacagc tttttttccg
     1261 cctttataga ctttcgatac attttctaat ctcagcaatc cgtgcacctc cgaagggttc
     1321 cgttattttt ctgaaaagta taatctttat tataagatga aatttgtaaa ataaaaagtt
     1381 tacaatgtgt tgaaattata tacaatatac gtattttttc atgttatccc gctgacaatg
     1441 cggatgttct tacaatcgct cccgatagct cgcatatcct gccgcatcat ctttttcatc
     1501 aactgtaaaa aatatgatat attgtcagca tgaaaagcca gtgaagggat gatcagccgt
     1561 ggaaaaaaac gctcttgata tcatcgggca tgctgaagag catctcattg agagaatcgc
     1621 cgagaatatg catacattcg gaatgccggc cacacttgga cgtgtgctcg gtattattta
     1681 tatgaaccgc aagccgatga cgttaaatga gctgtcagag gcgaccggga tgagcaaaac
     1741 gaggatgagc caggtggtcc gcgaaatgac cgatgccaat ctggctgaaa aagtgtttga
     1801 aaaaggcgtt cggaaagacc tttacgacgt cgagcgtgat tattaccaga cgtttatctc
     1861 cctatttacg gcaaattgga caaaggcggt cagcaaaaac aaaatgctct ataaaaagct
     1921 gaaccgcgag ctgactgagc ttctggaatc ggaaaatctc agtcccgata ttgaagaaaa
     1981 agcccgccag cttttggatg aactgaagga ttggctccat tattatgact ggctgagccg
     2041 tttgatagaa ttttttgaga gtgaagaagt gtttcagcat gtgccgaaaa tagaaaaaag
     2101 cagcacccga agataaccgg gcgctgcttt tttaagtcag gaaaccaata tcgggaacat
     2161 gcctttcaga ccggcgccga tcatgccgat cgccaccacc gccaaaatca gccccatcag
     2221 tcgggtaatg acgttcattt cggttttccc gagcttattg ctgatgaaag atgaatagtg
     2281 aaagaagata aacgtcatcg cgatgacggc cgcaatgccg ataagcacgc tgatgtaatg
     2341 gatgatgccg ccatggccgg ccgacagact catcaccgtc gcgatcgtac cgggaccggc
     2401 gataatcgga atcgacaaag gcgtcacgga tatatcggct ttctccttgt tctccccttt
     2461 ctcttcatga tggagagact gtacatgaga tttcttcgcg ttcagaagat tataagcgat
     2521 gccgaaaata aaaatgccgc ccgcaatacg taaggcatga atgttaatgt caaacagttt
     2581 aaagatcaga tggccgaaga ttaaaaaagc cgccaagatg ataaacgaca gcacggaagc
     2641 cttgcgcgcg atcgctgtcc gttctttctc cgagtaccct tccgtcagtg aaagaaaaat
     2701 cggcacgttt ccgatgggat tggagactgc aaacagtgaa atgaagacat gaatgatgaa
     2761 tgaaaacatg cgtacctcct tatggcttgc ggttattgag ttatgttttg ttctccgctg
     2821 tttcttatgc atggttttta ccccggggtc tgctttttat aacctcagcc ggacggtccg
     2881 gaaacagaaa aaaaccgtcc taaggacggt tttttttgtt tgctatctcc ataagccttt
     2941 tccgaatttc aacagccgat aaagcatttt caattttttt agcatgcgtt aatttccttt
     3001 ttcactctga atcaatgcgc cgagagacat gatatctatc agctccatta aaattctacc
     3061 ataatgggta ctttttctct attatcaatt catagagaaa gtgatttgta tatctttaga
     3121 aaactccgtt acatccgccc tattttcttt tataatgtaa atattgaaca aaatccctat
     3181 attacttgta aaaggagttt tagaatgtat tgttctcaat gcggccatca tactgatggc
     3241 ggaaagtttt gtgaaaagtg cggtgcgccc cagcccgggc agggaggcgc aggccaaacg
     3301 caaggccagg ccgctcaggc cggcgctgcg gctaagcagg cttcaaagca atttgcctta
     3361 ttcgtgcttg atgtgttaaa gagaccgtac caaacatgta aaacgacagg cggcgaacag
     3421 cttgtcagca gcatcatcaa catggtgctt ttctgcctgg tgacgccgat tatgttttat
     3481 attctcttaa cagacggctt tcgtgacgtc agttttaccg cgattgtggt caaaccggcg
     3541 cttacctttg cattatgcgt tttttgcctg tatctcttga tttttatcgc tttgaaggcc
     3601 ggcggcgcgc aggtgtcatt taaagattcg ctgtccagat tcggggcctt tttgattccg
     3661 tttacagcta ttttgcttct tgccctcatt tttatgctgc ttcatacaac cgtttgcttc
     3721 accattctgg ctgtcggtct tttaggagcg gcatttgccg tgcctccgct catgctggcg
     3781 agctatcagc atcagctcac tactaaggcg gatatcattt attctgttat cgtcatctat
     3841 ttgatcattt gcgtaacgtt tcaattcacg atcaagcatt atataaaaga actcatgaat
     3901 tatttcttct tttaaaaacg gaaacccccg ccgcctgatt ggtgcggggg ttttttttat
     3961 tgaatggatg ttaaataaat tcttccgtct ttaacaacgc cgccatacgt ccaattgtat
     4021 gttctgagct tcggactgcc gccggctttc gtaatataaa actcctcgta cgtgtgaatc
     4081 gtcaaatggg agcctttctg tgaaaagctt ttgacattca cttcattaaa tacttcggtc
     4141 gtcccctcgc tgtgcagttt tttgaccagt ttctgctgat cagcatacaa agggctcccc
     4201 tcttctaaat tgcccgccat gatggcaaaa ttgttaaggc tgacggcgct tgattgattt
     4261 gtcaggtaat cagtcataaa cgatgtgact tgctcgtttg tcacgctgcc tgaagctgta
     4321 tttcctttgg atgatgccca tgcggatgta taggttttcg gctggtcatt ttttattttt
     4381 tttacatttg tcccggaaga atctgaggca gggtcagctt tttcgaaaac ccatttttta
     4441 tgttttgtat catatgagag tacataatga aagctcggct cagcctcttc catatcaggc
     4501 ttcgtattcc cgtcgaaata agcagactca tgaagctctt tacccgtaac agttacttgc
     4561 cagcggccgt tctcttgaga aatcgcaaat gaatccagat caaagcttgt ctctttatac
     4621 tgatccttca aaaaggtgcc ggaactcttc atgccggata ccacttcttt cgtctgctct
     4681 ttccaggcgg aaccagcctc ggtcatctga tcggtatttc cgtctgccat cgcttttgta
     4741 tactgcttcg ttgttttgac aatcgtgtcc atgattgttt gttgtgtatc ttgatccggg
     4801 ataagcgtta agtccacatc agtactgttg atcggaacat cggcagtttt cattttcccc
     4861 caaggaaaat cagcctccac ggcggctgtc atggaaccgt cagttaagag cggaccgtat
     4921 gtaacggatg taaacggatc tttatggacg gacttgccgt ttatcagcag atcgcctttc
     4981 gcgcttttga agctgtctgc cggagtgaat gtcacatcct cggcgtctaa cggcaggtca
     5041 aactcaacat tccggctgcc ggccgcctct gcctcttgct ttttgacaac gtcaaccgtc
     5101 tcatttttaa gcttggcttc cgccgtgtag acaccgggtg catacgggcc gaagatttgg
     5161 gtttcatcgg cttttttgac cgtacctgtt ttctcgctgt tgatataaag atcggcgcct
     5221 ttataattgc ttgtgacgcg gaaataaacc ggatcgactt tcagttcgta atggtcaaac
     5281 aaaagaaggg tttttccctc ttttttgacg tataccgcat ctttttctga tgaattgccg
     5341 cgaagcgatg ccagcagttc atcgtgtttc tttgcgtatg caaggagcgg tttgacattg
     5401 gtctcattca gcttcagttt tttgtctgaa ggagtgagca gggctgcgag ctttttcgtg
     5461 tccccgtcat gaaccgcctg ttcgaattga tctgtgagcc ttttttcaga tgtcagccag
     5521 gctccggttt tatatgcggc aatcaataag atcagcgctg cggcaatgcc tccccatagg
     5581 aagagcgttt ttttagggat cggctttctc ggctgtgatg cggattcagc cgcctgccgc
     5641 tccagccggc ttcctttccc gatcggtttt ccgcattctt tacagaaatg cgcctcttcg
     5701 ttgttctgct ggccgcaata cttacaaaaa aacatgactt tcctcctatt caatctgcaa
     5761 aacttgtata acttttccta tgtttcatat tttataataa agtagaatga ttttggagtt
     5821 attttgaaaa atagctgtcg atcataacgg aggaggagaa acggacatgc aaaaactgag
     5881 catccgaaaa gccgcggagc cggatgaagc gctgtatgaa ctattgctgc tggccgatcc
     5941 gtcgaaagag attgtcgatg attatcttgt aagaggagaa tgctatacgg cttggacgtc
     6001 agacgagctt gcaggggtct acgttttatt gcaaacaagg cctaaaacga tagaaatcgt
     6061 aaacatcgcg gtaaaagaat cgctgcagaa caagggattc ggaaaacagc tggtgcggga
     6121 tgccattgaa aaagcgagac aatcgggagc tgacacgatt gaaatcggca ccggaaattc
     6181 cagtattcat cagctgtcac tctatcaaaa atgcggattc cgcattcagg ctgtcgacca
     6241 tgattttttt atcagacatt atgatgaaga catttttgaa aacggcattc aatgccggga
     6301 tatgataagg ctttatttgg acctttaata aaagaactgc caatgatgcg attaaacccc
     6361 gttttcgaga cagggataaa aacactttta aacagccaat tgccgctcgt ctatcaatga
     6421 ttggctgttt agttcgtttg aatacgaata ttgttattat aaatgtaatc gttgacagtg
     6481 cattctacga tgacgggcgt ggttttgttt taacagcttt tctgacacta tgcaacacgc
     6541 agctctcagg cagaattggc agctgatcaa gtgtgtgtcc tgtttatctc caatcgtaaa
     6601 agcattcact tctccattgt atacttccaa tatcgcgaac agatacaatt attctgacta
     6661 taaggaaaat ccgggaagtc tgttactatt ttttcaagag ggagattagg atgaaagttc
     6721 catattatca gctacggcat aaatatgctc atttttcttg catccttaat ccggtactgc
     6781 tactgatttt tctgaatgat acgctgaaac gttttatggt taacacgcat ttcctttttt
     6841 attagggaag tgatgatcca atagccctat cgatacccat gctttcggca taatgcgcca
     6901 atgtgttttt ccaaatgccc tttgcactga ttcttcttca catttttctt tcagagacaa
     6961 taagacgctc gtgagatacc taaaagatca cagatatctg caaaaccttc tacaagtccg
     7021 actgaagttt ggctattaac ttcctttcta attcgttgta ctcttttaac acttcattcg
     7081 gctgtcgcaa ataacgattc tctgcttgca gtctctggtt cggaagtaaa ccccagacca
     7141 tttccgtaag tatattgctt ttcaacaggc tgttcgaatg tatatcccca gctttatgct
     7201 atctaatcca agtctgcacg tccgtgtatt cttaatattt aatttctgca tcatctcttt
     7261 catcggcacg cctgccaatc tcatgtctac accttctgtt tgacttcaac cggatcactt
     7321 actcttattc catagaaaaa acacctccaa gtctaatacc ggataacagt catccgtttt
     7381 caaacttgaa agtgtttttt tttttggctc atcttatagg tcagtccctt tgttttttct
     7441 aaagacataa agttgcaatc ttttgttggt aggaacatca agtaatagat taaaacttaa
     7501 taatccataa aactcttatg ttctttatac cattctaatt ttaaattcat taaaataatt
     7561 ttaaagttta acacaaattt ctcagttgct gcccaaagga ataaaatctc ctcattgatc
     7621 ttgatgttta agatataatt atacttattt attattattt ttgtatctag cataaaaata
     7681 aaggtcaatt aacgatccaa tcaatattcc tatggaaaga ccatacggta aaatatcaaa
     7741 aacaactcct aaaaaaagac ctaaacaaaa acctattact agaaataccg ctccatctcc
     7801 tttatagttt ttcaaatcaa acaactcctt aatagtgatt atgatgaata tgttttttgt
     7861 tttttcgttt gtgaacgata tagattacta tatacccctt ctaaagcaat cagttcttca
     7921 tgtttaccaa cctccaccac ttcaccttta tctaggacaa ttataaaatc cgaatccata
     7981 attgttgaca atctatgcgc gataaccact cttgtgcatc ccatttcact taaatattta
     8041 gaaatcaatg tttcattcac caaatctaat gaacttgtag cctcatctaa aattaaaatt
     8101 ttagggtcat ttaaaagtgc tctggctagt acaatccttt gtcgctggcc acctgataaa
     8161 ttcataccca tttctgaaat aggtgtatta tatttcattg gcatactttc aatttcttta
     8221 tctatttgtg ctgctttcgc tacttttctc actttttcta tactaatatt tttattattc
     8281 aatgtgatat ttttcagtat agaactatta aacaaggtaa tatcctgggg tacaattccc
     8341 atttgtttgt ataactgttt tctatctaat ttttcaagag ggatactatc aaaacaaatt
     8401 tgtccttcag tcggatcata aagccccatt attaacttac taagtgtact tttaccagaa
     8461 ccagatgaac ctactatagc aattttctgc ccttctctta tttccaaaga aatattctta
     8521 agcacctttg gagaatgttt agtataagaa aaagagacgt tttcaagctt tacatttcct
     8581 cttaatttaa ggtttactgc attttcaata tttttttcac attcagtctc tgtaatatct
     8641 ttaactcttt ctaagtaaga agtagctaag ataaactgag tataagtacc aaataaagca
     8701 gttgttaatc caaaaaaagt aacagataaa gaatgatatg cgataacctc tcccattgta
     8761 aatttattat caaaaaataa tagcagttct aatattaaaa taaccaaggg agcaattgtt
     8821 tgaaaaacct gagttactgt attaactaca ttttgtaaaa tggatctttt tttgaatcgc
     8881 tttattactt cattaaaact gttattccaa gttgagaaaa tttcattttc cattcccgaa
     8941 attttaatgg ctgcgataga aaaaatagac tcgatttgaa tggcttgaga tttactttgc
     9001 tcagctactt catcatcgat ggcctgcgcg acagcaggtc tagtcaaaaa catgaatata
     9061 gtgttaattg caaatattaa tattgttatc aaggttaatg gtatagattt aaagaacata
     9121 tacgctaaaa taaaaactac cgctcctaaa tcaattaggc cagaaattag ttgagttgat
     9181 aaaagctctc tgaatccatt catgctattt aacctaaata acaagtcacc aggtgatcta
     9241 agatcaaaga atttaaaagg aagttttaga agatgagcaa atgtatcaac aacaagattt
     9301 ttactaagga atatattgag gcttatcatt ttgagccctc taaacaaaac aaacattcca
     9361 tacaatattg atattaaaaa tgttatccaa acaatattac ttattgaatt taaattatta
     9421 tactcaatac ttgtatctat aagcttctgt accaaaatag gtacatacaa cgtcaataaa
     9481 taacttatta gagataaaaa tactataata gaaaataaca atttatagtt tgtaatattt
     9541 tttaatacac caaaccatac attcttatct tttcgtttat tgggagtgaa actttctgaa
     9601 ggaactgcgt ataaaatata ggacgagaaa cctttcttaa actcttcttc tgttaatttt
     9661 cttcgtccat tagccggatc tataatataa taataatttt cctttatttt ttcaacgact
     9721 ataaaatgtt cattattcca atatgcaata aaaggaacat taattttttt taaccctaga
     9781 atagtggatt tatatatatc cgccttaaat cctttatgaa ctaataagtt ttttaactgc
     9841 ttaatagtaa gtccgtctct tccagcctcc aaaaatgacc ttaactcaaa aagagtttcg
     9901 ttactgttat aaaaacggat caacatagca caacagcaaa gtccacattc agtttgttgc
     9961 aattgtttta caataggtac tctctttttt ttcttcacta tcattcattg taactcctta
    10021 cttccattgc taacaatgaa ggattgacag gattgtgtaa ccttaataag ctgtagccta
    10081 cgcctccaag tcccagcata aatgtattta attcaaaatg atcctgtaaa cctggaataa
    10141 aacctttatt tctaatataa ttaattgcat tttgagcttc tttaaatgct acttcctgaa
    10201 gatcaatatc attgagaagt tcacttaatt tcaataatat atctatatta ccaaaaatac
    10261 catgacataa gctatgatca gttgtttttt taaatccatc ggaaaggagc ttgcttatag
    10321 cgcaatttaa atctttatca acttctttat caactacgtt ctctttgttc tttaacagat
    10381 tttttaaaaa agctcttgat agagctatac ctcccgcacc atgacaccaa tatactggat
    10441 cagagttccc ctctccttct cttaaatcct tccaattaga ggtattcaaa tcaaaaaact
    10501 tattttctct tttcaataac tcttttccta aagttgtgta tttttcgtct ttagtaatgt
    10561 gacccagata acaaagagcc aacgtaaaac cagaatatcc atgtgaaagt cctgttagat
    10621 aattatattt accattcttt tctaagcatt gatataaagt attacctagt ttacaacaca
    10681 cggagtttaa aatatctaat ttagtttcct tatataggtt taataaaaaa acaataagac
    10741 tagatactcc ccctacaata tccaatggta tatctcctga aatattcatt tcatttattt
    10801 tattaatata ttttttaaat ttttcatagt atttataatc atttgtataa gtgtataggt
    10861 ggtaatatat ataggctaag gaacctatcc ctgtaaataa tgataaccgg ccatccatct
    10921 tatcatcact caaaaaaagt tcttcaatac ctctcattcc tgcaaaggct aaatcaaagt
    10981 actctttatt accagtttct tttccaagta aagctaagaa taatattact cctccacctt
    11041 catataagtc aaagttcaat ggacccaatt ttactttatt attctcagat attataggtg
    11101 ttacccaagt acatttgctt ctatcattat tccatattgc tgtttctaaa aataagtctc
    11161 ctatttctgt tgcgcactct aaataatttt tattattatt tccaaataat ttaggacgat
    11221 atttcttatt gtgtttgttt gttcttttcc aactgtcttt tatagttgta gtaagtgaca
    11281 ttcgaatata atattgctgt ttttttaaac ttgttttact tatactttta attttgttta
    11341 atacaacatc aagtaaacac tctctaaaaa aatttactat acttgtactt ttattacaaa
    11401 tcaaatccaa agaattatac attgttgaaa aatacggaac atcattacac attaaagatt
    11461 ccaactcatt taaattcttc ttgctaaatt tatctgttac tccttccgca atatttattt
    11521 ttttaaataa ttcctttctt tcctcaaaac tagataaata atttggatga gtggaagctt
    11581 ctaaaaacct tgcatatata ctggtagctc ttaaaacttg ccttacttcc aggttgctgc
    11641 ttcctactgt ttttaccaaa tcataaaaac cacttttatt ttctaaaaca aaattataac
    11701 aatctgtaaa accttttaat atttcttcaa tataatcttt agggtctgcg gctttcccat
    11761 tatatgcagc tctgttttga gtactgttca ttattactga ttttttagtt aactgaattt
    11821 catcagttcc ttcgaaatct ataatatacg atttccatat ttctgatgtt tgattttcat
    11881 catttgatat tccgccaagg tcaaaatcaa atatagaagt ttgtaaattt aatgggagaa
    11941 gcatagtgcc aagaactgag taattaatat cctcatgaaa attatcaatt aaattattat
    12001 ttcttggttt atacatagaa ttatttttta tcagagtctc caagtcaata acaacaggat
    12061 attcgccatg tgcaattaag ttttcatgat gcaaatcatc gcatcctata atgtgaaaaa
    12121 tagataaact tacacctact ctataaaaat agaagttcag tttttcggaa gtctcacatt
    12181 ctttataatc aataaactct tgatagccat agtctttata attaagtgtt ctaattttat
    12241 aaattttttt tagaatttta tctgaattat taacatagtc aactatacta ttaaataaga
    12301 tatcaggaga taaactatgc ggcttatata caattttccc ttggtttgtt tcaattatta
    12361 agacattttt ccctccatta tgagtgtctc cgctgctaaa ataaatattg gagacttcat
    12421 caaattcaat ttttagttct ctataaatgt cttgacgatt ttttcttaaa ttctctagaa
    12481 cttctttcaa gtacaagatt ttatttgata ttctactaga aattaaatag gttaaaacag
    12541 gatacttatt caaaattcca gccacatatt cactcttaaa aattaaatta ttataattct
    12601 tatagcgtaa ccttgaatct tttccttcta ataaaccatt ttcttttctt tcattaatat
    12661 caacgattaa agttcttata cataactgaa ttaattcctg gctaaaagcc tctaacgcac
    12721 tacttataat tttatgtttg ttaagtttta aattattttc cttacttgcg ttttctaaag
    12781 tattaactaa tttttgttga taaaaatcta aaaagaatgt ataaaagttg ccaaagtaat
    12841 ctttgttttt tattcttaat ttttctactt cgtttgtcgg cgaactgaaa ttaattacag
    12901 catctctgat gaaattattg ttttcatagc taatatccat ttataacctc tccaaaagat
    12961 ttaatagaga attgtttgtt aaaacaattc tctattaaca cattatgttt atttgttaca
    13021 ctgttttgta cacgctgatg ttggacatga tgctgcactt aaagtaactg taaaagtcgt
    13081 tccagtgagt ccaatagttg cagttaaaac gactgttgct ggagtagctc ctccagtagc
    13141 attatcacca ttagctaacg atataagttc gtcttcttca ataaaacctg aagccttttt
    13201 gaccatatct ttcttcataa ttctctcacc tcctttcaag tatgactttg aataagagta
    13261 ttaaagctta ttctaaccat aaaaaattgg gaacaatttc cggagcataa tttttgatca
    13321 ttgagtaacc tattcctgat aatccgatca ttaaactata tgatctagta cagactaagt
    13381 ctctctttct ccatttcttg gtcaaaacat tttcaaatag gtcttgataa gttcttaaac
    13441 atctattctt caaattaata ttgttagtta aatcagaagc ataattcaat atagaaagca
    13501 cacctaaatc tccatgacaa tatgtagggt tattgccaat gccattacga atagaagaat
    13561 ctattgcagt cgatatttct ttttcaatgt actcgtcttc aaaaccatta tcttttaaaa
    13621 tcaatttact taaaagtata cctggagctc cgtgacacca tccattagct aacttatctt
    13681 tattttctgt ggtataccaa ttattgtggt cttcagagta caatctcctt tcaaatctta
    13741 aggccctttg aatgacttcc aataattttt catcatttgt taacttaaaa tatttatata
    13801 agtatgcgat aaaaccagaa ttaccatggg aaaaccctga atatgctgct gaaaatttcc
    13861 ctggccacga tatttgctcc tcaaaatttt ttgctacact taatatatgt tcacaatgag
    13921 tatgtgaaat ctttaaaatt tcctttttgt tattctcttc agtaatatct ggtattatgg
    13981 aaagcataac tgctaaacta cctaaagacc ctcctattaa atcgtatact ttatcgaatt
    14041 tacctaactt cgataaaaca ccgatgtttt caagcgaggt cttccttaat tctgaatctc
    14101 caaataaatt agataactta tttaatgtat aaaaatatcc tgatatacct tgaaatgcac
    14161 ctattaaata tgggtgatct tcttttattt cagagataaa cttctgtatt ggtctcatag
    14221 tttcgatagc tgcttgctta aaatcctttc tgttgaggat ttcgcccaag taccctaaaa
    14281 atagagcaat ccctgaatta ccattatata tatcgaatcc caatacattt gcattccaaa
    14341 tgtcttcctc aataccctca agactaggac ctatccacat tctatctttt tgttttttat
    14401 ttataccaca tacactgttt tcaactataa attcgcctat ctgggttgct tcatctatcc
    14461 aattttctga cttaatttta tttaagcttg cagctttaga gaattttata tcagtaactt
    14521 ctttcaatct tttttcatta ctaatgtaag acatttcaat aaaatcaatc tgtcttttca
    14581 aatcttcttt cgaaagattg aaaatctttt gctttactgt ttttattgga ggttcttcca
    14641 gaatgctgta aattcttttc cctctagaat ctattaaatg ttcatgttca atagaggatc
    14701 taaaaaatgg aacgtcccca gttaataaat ctttatattc tgagttcaat atatctttat
    14761 actcttgtat ataatcaatg ccgattctat gtaaaataat cttacgtcta taggtatctc
    14821 tcataaaatc tggatgactt gagattctta aaagctgagt gtataagtaa gtgggtctga
    14881 agataaacct gctatttgtt tctttaaaag tttgagaaat tttatcccag aattcatctt
    14941 tatttaacat cacccaacta tataaacttg caaaaccatc tttaatttgt cccgtataat
    15001 tttctgaata taagtaagac cctgttttaa tggaagggtt gtttaattga ggtttaatga
    15061 aagtattttt tcttaaaatt ttaatcgtat ctgttcctgc attttcaatt actaatgatt
    15121 tatgaggaga gagttgttcc ttataggcag ctaatccccc tatatctaga cttatgtctt
    15181 tgtctcctac tctcttagaa atttttgtag gcaataaact tattgactgt acagagttat
    15241 caactaattc agttgcttta acaacagctg actttttatc aatttggtca acctttagtc
    15301 ttgcatgaaa taatgattct aagtcaacta atactgggaa agaaccatgg gctattaaat
    15361 tttcatgatg aaaatctact gcatttagaa gatacagtaa acaaagaaga ttacctgaac
    15421 gagtatagaa atcatttgct tcgtttttat taaaacaact tttataatct atgtactcca
    15481 tccaacctga atcatttact gtatgtattt gaactctttt gaaatttaaa attcccggta
    15541 tgtttttctc gcccaaccaa tataatactt cctggaaacc ttgttcaagc gttaaatctc
    15601 tgggtttata aattattttc ttgccacttt taaaatatat tgttgaaaca gattttcctt
    15661 tttgatgagt atctcctaga ccggtggtta tatttgttat tgcacctaaa tcgttatcag
    15721 agttgaattt agagtttaat gaactaattt ctcgttttgt gttttttatt atttccatta
    15781 catatgtgaa ataatcatca atcgttacac ataataaact tgttaatact tcatattctt
    15841 tataaacact ttttaaaaat gattcatcat ttaaagatac aactaaaaaa tgatttagtc
    15901 tttcttccgg ggtagtcccc tctaaattcc cctctaatct tgcaatattc acttccaaaa
    15961 caagaaccct aaaagctttt tcaaacatta aatccattat atgtttaatt acctttttca
    16021 caaattcatc ctcattatct actgcatctt caattcttac ttttactaag aattcttcaa
    16081 ttttgcagtt aagaaaagga gaaaaaaaat gaaaaaatgg attatgctct aaaaattctt
    16141 cagaatttct cactaaaaaa tcactttttt tatgatctaa gactctatca atatctataa
    16201 tacttttatt ttgctcaata ttagtatcgt ctctaattaa tgattgaatc gtcttaccag
    16261 atacatttaa aaaaatcttt tgcaattcat ctttattgtt aacctcagga aacattttca
    16321 tccagtattg gagattatat ttgttagttt tcaaagttaa tgatcctacc ttaatatatt
    16381 ttttgcaaaa taggcagtta attacactgc ctattttata cttatttcag caagtacctt
    16441 gacattcttt agtacctgta caaactttgc ctttatttcc aagaacctca cttactaaaa
    16501 tcccccccag gctagtagtt gttgtattcc aggtattgaa agctcctgaa acttcatgtt
    16561 ctttaatttc ttcaagaaca tctccacatg ggtctatcaa atttaaatct tttgtcactt
    16621 tcaattctgg tgtttttaat atctttgtct tcttcatact atctacctcc tcatttttta
    16681 ctggataaaa tctctattaa cctgttcaat aataatctac catattttcc tatagtaaac
    16741 aatgggtttt atgtaatttt tttattttat gagattctcg gggggggggt attttatact
    16801 ttattttaac agggcagttt tttatactac caaaaagaag tcctttgttt ttaggaatgt
    16861 aatttttaaa atgctttagg aaagaaataa aacggttttc acattactgc attacaaatt
    16921 ttaaaataaa aaatatcgta atcctgcctt ttgcaagtaa aagaacaaca gttatgttac
    16981 acaggaactc ttatttaaag gagagaatac tttcttttgg agttgtcatc aaaattattt
    17041 agattaataa ggaattaagt aactattatt ttgttctgag agggcgtcaa cacaatcagc
    17101 tactacctta acttttataa gtattatatg cagctaaatt ccgggcagct gtagaccatt
    17161 gttttttatc tagggcacag ctaatgacta tccgttctgt atctgagatg gctgaattaa
    17221 ggatataagt atctgtgatc acaagattgt ttacttctcg ttttaggaat attgaaaggg
    17281 tcagaccatg ctttgtcatt aactaaatac tagttatact cacaacctta cattaattga
    17341 atgttttcat taaatttgaa gaagtgtccg agttggtgag ttttattgag cggatactat
    17401 gatccaatgt atacagttgt tcaaacatgg tttatttttc aatacttctc tcggggtcta
    17461 agagagtttt ctcctgatgc agtaaccagg ttcctactag ataccgggag ttccatatca
    17521 taaaatgaaa atgttatcat ttcttgtatg ttttcttgat tccaagcgtc tgctattcgc
    17581 taaaccgaca gttactccgt aaaatgtaat aaccatcctc ctgtaagctt taaagcttca
    17641 ctgtcctttt tcaagatcgg ctagtgaaat ttttagcctc agatattcga tccgagtaat
    17701 attagtaggt ctgtactctc gaacatccat tcatcaaggg agatatctgg ttttatgcgc
    17761 taagctcgag cgtagttatc atttctttat tcaccctatt gtcatgactt ttaaaagtgc
    17821 ggcatcttat ttgaaacttt gcaagttcag tttggtctta attatccata ttcccaacct
    17881 aacattgtag gaaatgcgta aagataaact gattttgatc attcaaacac tccaactcaa
    17941 aaaaaccctg actgcttttg tcagggtaat agaaattata gaaattcagc tctcccacac
    18001 ttaaaagggc ttggctgcag atgcagccaa gcccttttta tgcttactta ttcaagttat
    18061 agaaagagtt gataccgtgg tattgagcag tttcagccaa ctgatcttcg atgcgaagaa
    18121 gctggttgta tttcgcaaca cggtccgtac gggacggagc acctgttttg atttgtcctg
    18181 cattagttgc cacagcgata tcagcgattg tgctgtcttc agtttcacct gaacggtgag
    18241 agataacggc agtgtagccc gcgcgtttcg ccatttcgat cgcatcgaat gtttcagtca
    18301 atgtaccgat ttggtttact ttgatcagga tagagttgcc tacgccgttt ttgatacctt
    18361 cagcaagctt tttcgtgttt gtaacgaaaa ggtcgtcacc gacaagctga acttttttgc
    18421 caagacgctc tgtaagaagt ttgtggcctt cccagtcgtt ctcgtcaagt ccgtcttcga
    18481 tagagatgat tgggtattta gaaaccattt cttcgtacca gtcaaccatt tcagcagatg
    18541 ttttcacaac gccttcgcca gacagatggt atttgccgtc ttctttgttg tagaactcag
    18601 aagatgcagc atccatagca agtttcactt cttcgccagg tttgaagccg gctttttcga
    18661 ttgcttcaac gattgtttga agcgcttctt cgttagaacc aaggttcgga gcgaatccgc
    18721 cttcgtcacc tacagctgtg ttcattcctt tagcagaaag aacggatttc aggctgtgga
    18781 agatttgagc gcccatgcga agcgcttcac ggaagttagg cgcgcctaca ggcataatca
    18841 tgaattcttg aatgtctacg ttgttgtcag catgttctcc gccgtttacg atgttcatca
    18901 tcggtacagg aagcgttttt gagttgaatc ctccaaggta ttggtaaaga ggaatctgta
    18961 agaaatcagc agctgcgcgc gcacaagcca tagatacgcc aaggattgcg ttcgcaccga
    19021 gtttgccttt gttttcagtt ccgtcaagct cgattaaaag ctgatcgatt gcgttttgtt
    19081 cagttacgtc aaagccgaga agctctggag aaatgatttc gtttacgttg ttaacagcag
    19141 ttaacacgcc ttttccaagg taacggtctt tgtcgccgtc acgaagctca accgcttcgt
    19201 attcacctgt agaagctccg cttggcacta atgcgcggcc gaaagctcct gtttctgtat
    19261 atacttcaac ttcaactgtt gggttgccgc gggagtcaag gacttcgcgt gcataaacat
    19321 caacaatgta tggcatgagt ttgtctctcc ttttgattta cgcttatttt tgaattaaag
    19381 atgttcctgt catttctttc ggtttttcaa caccgagaag gtctaataac gttggtgcga
    19441 ggtcgcctag gattccgcct tcgcgcagcg tcacgccttc tttcgtcaca atgacaggga
    19501 ctgggtttgt cgtatgggca gtgtgcggtt cgcctgtttc tgtaatcaga atgtccgcat
    19561 taccgtgatc agcggtaatg atggcatgtc cgcctttagc gatgatggcg tcaaccactt
    19621 cgcctaagca ttcgtccact gcttcaattg ctttaatcgt cggttcgacc attccggagt
    19681 ggccgaccat gtcagggttt gcaaagttca ggatgatcgc gtcgtgcttg tcagccgcga
    19741 tttcttttac aagagcatcc ttcacttcat acgcgctcat ttcaggcttc aggtcatatg
    19801 tcgcgacctt cggcgagtta atgaggatgc gctcttcgcc cgggaattct tcttcgcggc
    19861 cgccgctcat aaagaacgta acgtgcggat acttttcagt ttctgcaatg cgaagctgtt
    19921 ttaacccgtg ctgtgctaat acttcaccca ccgtattgtc aaggtttacc ggtttaaaag
    19981 ccacatatcc gtcaacagat tcactgaagt gagtcaggca gacgaaatac aggtttttcg
    20041 gatgattttc accgcggtcg aaatcgcgga aatctttgtt ggtaaacgtg tttgaaatct
    20101 ggatagcgcg gtccggtctg aaattataga aaatcacaga atcgccgtca tgaattttcg
    20161 caacgggttc accgttttct tttgtgatga cggacggaat gacgaattca tcatgaatgc
    20221 cgttcgcata agaatcatcg actacatcca tcgcgttgcg gtaagacggg ccttcgccgt
    20281 aagccattgc gcggtacgct ttttccacac ggtcccagcg tttgtcgcgg tccatggagt
    20341 agtagcgtcc ggaaatgctg gcgatttcgc cgacaccgat ttcttcgatc tgctcattca
    20401 gctgctgaat gtaagttttc gctgtttgcg gacctacatc gcggccgtcg aggaaaccgt
    20461 gaatatacac cttcgtcagt ccttcacttt tcgcaagctt cagcagcgcg aataaatgat
    20521 tgatatgact gtgtacgcct ccgtcagaaa gaaggccgaa caggtgcagc gctttgtcgt
    20581 tgtctttcgc gtttttgatg gcgtcaagga acgtttgatt gcgttcgaat tcgccttcgc
    20641 ggatggcaac gttcacgcgt gttaagcttt ggtacacaat acgtcctgcg ccgatattca
    20701 aatgaccgac ttcagagttc cccatctgtc cttcaggcag tccgactgct tcgcctgatg
    20761 ccgtcagcgt ctgatgaggg tattggttcc aataacggtc gaaattcggt tttttcgctt
    20821 gtgcgactgc gtttccgact gtttcattgc gtaatccgaa cccatcaaga atgatgagtg
    20881 cagctggttt tttactcata ttgaccttcc tccaataatt gaacgaatga ctgcggttca
    20941 aggcttgcgc cgccgaccaa agcaccgtca atatcggact ctgccatata ttctttaata
    21001 tttgcaggtt ttacgctgcc gccgtattga atgcggagct tgtcagcagt ttcctggctg
    21061 aagctttcag caacgacttt acggatatgc gcgcagacgt cgttagcatc tttcgctgta
    21121 gaagatttgc ctgttccgat tgcccagatt ggctcgtacg caataacgga agcggcaact
    21181 tgctcttcag aaagacccgc aagacctttt ttcacttgat cggcaacaag accatttgtt
    21241 tttccggctt cgcgctcttc aagtgtttca cctacgcaaa tgatcggcac aatgccgtgt
    21301 ttgaaagcgg catgcgcttt tttgttaact gtttcatcag tttcagcgaa catttcacgg
    21361 cgctcagagt ggccgatgac gcagtaatcc acgccaaggt ctttcagagc gaccgggctg
    21421 atttcacctg tgaacgcacc gttttcttca aaatgcatgt tttgggcgcc gactttcagg
    21481 tcagttcctt taacagcaga agtcagcttt tctaagaaaa gagctggtgc gcaaacaacg
    21541 gcttccgctt tgtctgctgc tggaatggaa gatttcactt cttcaacgaa gctgacagct
    21601 tcgccgagtg ttttgttcat tttccagtta ccggctataa ttggttttct catctgttcc
    21661 acttccttat agcagttttt atttatcgtt cagcgcagct acacccggaa gctctttgcc
    21721 ttccatgaat tcaagggatg cgccgccgcc tgttgagata tggctcattt tgtcagcaag
    21781 gccgaatttt tcaacggctg ccgcagagtc tcctccgccg atgacagagt atgtatcgtt
    21841 tgcctctgcc aatgcttcag ccactgcttt tgtgccttga gcgaacaagt cgatttcgaa
    21901 tacgcccatc ggtccgttcc atacgacaag tttgctgttt ttgataactt cagcatacgt
    21961 ttcgcgggtt ttcgttccga tgtcgatcgc ttctaaatca cttggaatct cagagatcgg
    22021 cacgatttga acgtttgcat cgttagagaa atcatcagca acgagcacgt cttccggcat
    22081 atagaatgta acgccttttt ctttcgcgcg gtccatgaat gattttgcaa gttcgatttt
    22141 atcttcttca agcaaagatt taccgacttc atagccaagc gcttttacga atgtgtaagc
    22201 aagacctccg ccgatgatca ggttgtccac tttatcaagc agactttcga ttacgccgat
    22261 tttgtctttt actttcgcgc cgccgatgat tgccgtaaac gggcgctcag gatttgtcac
    22321 ggctttgccg agaacgtcaa gctctttttc catcaggaat cctgcaaccg ccggcagatg
    22381 ctcggcaatt ccggctgtag atgcgtgagc acggtgggca gcaccgaatg cgtcattgac
    22441 atatacatcc gcaagctcag caaatgcttt agcaagctca ggatcgtttt tctcttcacc
    22501 agggtagaaa cgtacgtttt ccaatacaag aacgtctccg tccttcatat cagaaatttg
    22561 tgcttttaca gcatcgccgt aagcttcatc cgcttttttc acttctttgg cgagcagttc
    22621 gcctaagcgt gcagcgacag gagttaaacg aagctcctca accgtttcgc ctttcgggcg
    22681 gcctaagtgg ctcgcaagaa ggactttcgc gccttggtct gcaaggtgtt tgattgttgg
    22741 aagcgcagcg cggatacgag tatcgtctgt tacttccccg tctttcattg gaacgttaaa
    22801 gtcaacgcgg cagaatacga ctttgccttt tacgtcgatg tcttttactg tttttttatt
    22861 catgccttag gagatcctcc ttcaaaatgg tttgcatagc acgaaaaacg tgaaacgtga
    22921 aaccgcctca tgatgcttcc gccgcggggc agattgcagc ttccgggcac ggggcagatc
    22981 gtcttctgag ccagggcagg cggctaagaa aacgaaagtg ccgcggaaac ttcaaaacgc
    23041 ggacgttctg cagcaatccg gcgctttctg aaagccggtt ctcatggaaa aagggaaagg
    23101 gagtccgtcc ccttcccttg tccgctttca ttatagcgtt tctgtccgaa agaaccaagt
    23161 ccggcccttt ccgggagcta tgaattaaag accttgtttt gcgatgtaag ctgcaaggtc
    23221 aacaacgcgg ttagagtagc cgctttcgtt atcgtaccaa gagattactt ttaccatgct
    23281 gccttccata accattgtag aaagagcatc gattgtagaa gagttagcat tgccgttgta
    23341 gtctccggat actaatggct cttcgctgta gccaaggatt cctttaaggt cgccttcagc
    23401 cgcttcttta agagctgcgt ttacttcttc agctgttact tcttggttca gttcagcaac
    23461 caagtcaact agagaaacgt ttggagttgg aacacgcatt gctccaccgt tcagtttgcc
    23521 ttttagttca ggaagaacta gagaaactgc tttagcagca ccagttgatg ttgggatgat
    23581 gttttcagct gctgcacgcg cacgacggta gtctttgtgc ggaagatcaa ggatttgctg
    23641 atcgtttgtg taagagtgaa cagttgtcat cataccgcgt ttgatgccga atttatcgtt
    23701 aagtactttt gcaaacggcg caaggcagtt tgttgtgcaa gatgcgttag agataacatc
    23761 gtggttagcc gcatcgtatt tatcttcgtt aacacccata acgattgtga tatcttcttc
    23821 gttagcagga gcagagatga ttactttttt cgcgccagct tctaagtgtt tcgcagcgtc
    23881 tgcgcgtttt gtgaagaaac cagtagattc aactacgatt tcaacgcctt gtttgcccca
    23941 gctaagttta gcaggatcgc gttctgcaga aacttcaatt gttttgccgt taacaacaag
    24001 gttgttaccg tcaactgaaa cttcagcgtc taattttccg tgtacagaat catattgtaa
    24061 aaggtgagcc agcatgttag catctgttaa atcgttaacc gctactacct caacttcagg
    24121 attgtttaat gctgcgcgga atacgttacg tccaatacga ccaaaaccgt taataccgac
    24181 ttttactgcc atgattgttt cctcctttaa ataagtgaga gatatttata ttgagggatt
    24241 attcatccct taataacttc tttgcggctc cttcgtctgt gacgagaacc gtgttgcgtg
    24301 gctttttaaa gtaagcctcg atcgcctcgg cttttgatga tccgcccgct accgcaataa
    24361 tatcagggat ggcgtctatg tcatccagct gcattccgac agaatgcact ttgtgaacca
    24421 cttcgccgtc cgcgttaaaa tagtagccga acgcttctgt caccgcgtcg ttatcatcta
    24481 ttttctttaa gtcttctaaa ggcgtgtttc tgcgctgagc catagtttta gcttcgccga
    24541 ttccatgaac cagcatactc gctgatttaa tggtgttcag cacctctttg acagaaggct
    24601 cttcaataat agatgaatag gcgccttgtg acagctgtcc cggaacaaac aaaagccggt
    24661 aagtgcctga agccttctcc gccatatgcg cgcatatggt gttcgcctgg tttttcacat
    24721 cttcgcctaa accgcctctt gcaggcacaa acaaaagctc gcggttttta gaatccggcg
    24781 tcatcatttc ggcgacagct tcaattgtcg taccgccagt tacagcgacg atatttttgc
    24841 ctgaaaatct ttttttcata catgcgacag ccgctcttcc catttctttt ttgacccatg
    24901 gggattgatc gctgtctccg gatacgataa tggcatcctt cagatttaaa cgttctttta
    24961 atgtcttttc caaaagagtc aaacctaaaa catctttcat cgtatcttcc aaaacagaaa
    25021 gcagttcata gccctcttct gtcaatgtca tgccgtttgt cttaatatcg accaggttct
    25081 gttcctttaa aaactgaacc tcgcccctca gcacacgctc gctgattccg agactggcag
    25141 acaggcttct tcgcccgatg ggttctgtca gcctgatata ctgcaagatt tcaaacctct
    25201 tttgcataac gagcagaaga tcaggcaata attttttttg agcttgtatt aactggttca
    25261 tgactcaaac gttccttcct tttttgctgg acattatacg tcccgctatg acaaaaaacg
    25321 tcccgtcata gccaaaaaaa attatgtctg ctttctttaa ttattttaac aggatgacat
    25381 tgttaattca actgttaaag gtcaattcct cgacattctt cgcaggattt tccagtatct
    25441 ccttgataca gtcattatat acagaaacgg aatgaaggtg acagacaaaa gcccgccgga
    25501 gctgactttt gtcgtaaaac gctttcattt tatccaaagt ttttctattt cttctaatga
    25561 tttatttttc gtctcagggc agatcgtcac gacaaacaag aaacagagaa tattaatgac
    25621 ggcgaatatc cagaaggtgt acgcgagccc caacccgctg acatcatcgg cacgaactgg
    25681 ccgatcgccc agttggcccc ccataagaat atcgtcgcaa taccggcggc gcgtgcgcgg
    25741 aggtggttcg gaaagatttc cgaaatcatg atccacgtaa tcggcccgac tgatacgcag
    25801 aaagcggcga cgaatcccaa tatgatgacg actaaagccg gaccgctcgc cagcttaaaa
    25861 taaaaggatg ccccgattaa gatcatgaac agcgccataa aggcagatcc gacccccatc
    25921 agctttttcc ggcccacctt atcgactaaa agaaccgcga taatggtgaa aatcacttca
    25981 acgacaccga cgatgcatgt cgtgataaac cccgcattct gtccgaagcc catcattttg
    26041 aaaatttccg gcccgtaata cgtaattgcg ttcatgccga tgacctgatt gaataaagcc
    26101 agcagaatcc cgatcacaag cgcttttctc agccccggtt taaacagctg agacaatgac
    26161 cccatttttt ctaattgtaa agacgtttcg atttgtttga tttcttcttt cgcggtctgc
    26221 tcgccgttaa tgcgcgtcag cacggcgagg gcttcattcc ggcgccctgc tttcgcaagc
    26281 cagcgcggac tttccggcac gataagcagc acgataaaaa agatgacgga cggaatcatg
    26341 ccgtaagcga gcat
//
