LOCUS       NZ_CP079946            20435 bp    DNA     circular CON 18-AUG-2024
DEFINITION  Corallococcus sp. EGB chromosome, complete genome.
ACCESSION   NZ_CP079946
VERSION     NZ_CP079946.1
KEYWORDS    RefSeq.
SOURCE      Corallococcus sp. EGB
  ORGANISM  Corallococcus sp. EGB
            Bacteria; Myxococcota; Myxococcia; Myxococcales; Cystobacterineae;
            Myxococcaceae; Corallococcus.
REFERENCE   1  (bases 1 to 9431171)
  AUTHORS   Zhao,Y. and Cui,Z.
  TITLE     Whole-genome sequencing of Corallococcus sp. strain EGB reveals the
            genetic determinants linking taxonomy and predatory behavior
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 9431171)
  AUTHORS   Zhao,Y. and Cui,Z.
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2021) College of Life Science, Nanjing
            Agricultural University, No.1 Weigang Road, Nanjing, Jiangsu 210095,
            China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: FALCON v. MAY-2020
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 113.0x
            Sequencing Technology             :: PacBio RSII
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_019968905.1-RS_2024_08_18
            Annotation Date                   :: 08/18/2024 04:02:55
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,752
            CDSs (total)                      :: 7,680
            Genes (coding)                    :: 7,614
            CDSs (with protein)               :: 7,614
            Genes (RNA)                       :: 72
            rRNAs                             :: 3, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 3, 3 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 66
            CDSs (without protein)            :: 66
            Pseudo Genes (ambiguous residues) :: 0 of 66
            Pseudo Genes (frameshifted)       :: 12 of 66
            Pseudo Genes (incomplete)         :: 62 of 66
            Pseudo Genes (internal stop)      :: 2 of 66
            Pseudo Genes (multiple problems)  :: 10 of 66
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 09:46:24
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 7973999
            Orig. end                         :: 7994434
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP079946.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from College of Life Science,
            Nanjing Agricultural University, China.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..20435
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="phenazine"
                     /region_number="33"
                     /rules="phzB"
                     /tool="antismash"
     cand_cluster    1..20435
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="phzB"
                     /kind="single"
                     /product="phenazine"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20435
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[10000:10435](+)"
                     /cutoff="20000"
                     /detection_rule="phzB"
                     /neighbourhood="10000"
                     /product="phenazine"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10435
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="phzB"
                     /neighbourhood="10000"
                     /product="phenazine"
                     /protocluster_number="1"
     misc_feature    405..420
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 19.34"
                     /tool="antismash"
     misc_feature    complement(405..423)
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 22.48"
                     /tool="antismash"
     misc_feature    407..421
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.24"
                     /tool="antismash"
     misc_feature    complement(408..423)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 19.22"
                     /tool="antismash"
     misc_feature    416..430
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 16.76"
                     /tool="antismash"
     gene            424..2655
                     /locus_tag="KYK13_RS32355"
     CDS             424..2655
                     /GO_component="GO:0009279 - cell outer membrane [Evidence
                     IEA]"
                     /GO_function="GO:0015343 - siderophore-iron transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0038023 - signaling receptor activity
                     [Evidence IEA]"
                     /GO_process="GO:0015891 - siderophore transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1051:
                     TonB-dependent siderophore receptor"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002632222.1"
                     /locus_tag="KYK13_RS32355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="TonB-dependent siderophore receptor"
                     /protein_id="WP_223637665.1"
                     /transl_table=11
                     /translation="MPISFRSRPLRLVPGALLGASLSVVAAPALAQEPAAPQTSPAPES
                     PAPAQAPNPESSAAAPGDDEVFDLPTVTVESERATGPVRGYTARRSASGTKTDTAIVDT
                     PQSVSVVGREQMDAQQAQTVMEATRYTPGVRSDTFGADPRNDWFLIRGFTSQEAGYFLD
                     GLQLYSSSFATWRIEPFGLERVEAVRGPASVLYGGTSPGGLLDMEGKRPPVEGSVRHVE
                     VGGNTFANGYAAVDFGGAIDPGNHWRYRVAALARGGGTQVDETDNNRLFIAPALTWAPS
                     ENTSLTLHGSFLADRTQGQNFLPYVGTVVDAPYGRIPTDLFTSDKSLDHFQRNQSWAGY
                     EFSHRFNDTFTLRQNLRFAHLDLDFQTLYGVGYQGEPADAQLSRGNFVTRPRANLFTVD
                     TQGEARFSTGPVRHTVLAGVDFKNYRLDDEQGYEAGAPLDLLNPVRGDYTPTETRYTLG
                     RSTQDQLGVYLQDQLRFADRLSLTLSGRHDWVGMDVDNKLFPTSSYEGSESAFSGRAGL
                     LYHFDFGLAPYVSYSKSFNPVAGTKSDGSLFEPEKGQQLEAGVKYQPDAFPVLVGLSVF
                     ELKRKNFVTTDGAFNQLQIGEVRSRGFEVEANATLIHGLSLVGSASFYSLEITEGADFE
                     LGKRPVGVPEVLASLWLDYTFQDGALRGFGAAAGVRGVGSSYADRENTLDVPGFTLVDA
                     NVHYERGPWRAAINASNLGDRTYVSSCSSATACFYGERRRASATVGYTW"
     gene            complement(4253..5809)
                     /locus_tag="KYK13_RS32360"
     CDS             complement(4253..5809)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014399456.1"
                     /locus_tag="KYK13_RS32360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="PepSY domain-containing protein"
                     /protein_id="WP_223637668.1"
                     /transl_table=11
                     /translation="MKLSPRTFRIQFDLHAWAGVVASLFLFVIFFCGVFAMFREELEVW
                     QEPALHVAPPSESPPSFDAMLARVRERGPLPRGAHVGLLTHEETRFITAYLFEPTGMRV
                     LWLDPLTGTALPERSRLASELYWMHFFYRVPWGMELTGLVSVALLVALVSGLWIHLKDL
                     RTQWWRFRHTAKPRFSASDAHKVLGVFGLPFTAMLAWTGAVLCLAGLAAQGFGSTVYRG
                     QADRVTQLRGYSTPVREAAKQDAPMLSLDTVVDRARASVPGAEGTPRYVELHDYGDAKA
                     WAGVYFQLSPLGPDHFTHVDTVTGETFGSSVESRTPNFTVERLLFDLHAGRFAEELMKP
                     LYALLALAMCAVLITGNLIWLERRDPLRTRRGNRVLERLTVGVSAGLVSGTAVYCAANR
                     VLPWTLARRGDWEFGVFLGAWALGVVIALVPRGSSRRVGSVLSAVAAVLFGTVVVGDVL
                     TQDVNLFTALSRGLPRVFVAEAFLASMALGCGGLAWGLRRRKTAEPVPGGAAPEGPLVK
                     A"
     gene            complement(5806..6093)
                     /locus_tag="KYK13_RS32365"
     CDS             complement(5806..6093)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014399457.1"
                     /locus_tag="KYK13_RS32365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_223637671.1"
                     /transl_table=11
                     /translation="MSEGRADKAANHSVARTLAVVLGAPLAAFAAGAAVMAFLPVSGPW
                     AFVLGFQAVLPVWVGLACALPLTRSGRVAWGVCLAVVLPVAVALLLRGPR"
     gene            complement(6090..6377)
                     /locus_tag="KYK13_RS32370"
     CDS             complement(6090..6377)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014399458.1"
                     /locus_tag="KYK13_RS32370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_223646871.1"
                     /transl_table=11
                     /translation="MLSLAALCFCVSAVSWMGAGGRARWGAAVPGLASMACCVGDFGWV
                     AGLLVLGVLAMTAASGLVLVLAPRPSRARTFAWVSGVAGLVPVALMGVAR"
     misc_feature    6413..6428
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 19.76"
                     /tool="antismash"
     misc_feature    complement(6413..6431)
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 21.39"
                     /tool="antismash"
     misc_feature    complement(6415..6428)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 15.79"
                     /tool="antismash"
     misc_feature    complement(6415..6429)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 21.7"
                     /tool="antismash"
     misc_feature    6416..6429
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 16.74"
                     /tool="antismash"
     misc_feature    complement(6416..6431)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: medium, score: 23.95"
                     /tool="antismash"
     misc_feature    6419..6434
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 17.69"
                     /tool="antismash"
     gene            6559..6933
                     /locus_tag="KYK13_RS32375"
     CDS             6559..6933
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="KYK13_RS32375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="GFA family protein"
                     /protein_id="WP_223637673.1"
                     /transl_table=11
                     /translation="MTGTQSLKGSCHCGATRFEVAAPPKDITRCNCTFCSKRGVLWAYY
                     APEHVTFTRRENVGTYARNEPVVHHHCEQCGCGTWTDIPVWENNAPVPGRFKVGLNARL
                     FDDFDLDAVRVVFVDGRNLW"
     misc_feature    6582..6594
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 19.11"
                     /tool="antismash"
     gene            complement(6937..7809)
                     /locus_tag="KYK13_RS32380"
     CDS             complement(6937..7809)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KR (9-165). E-value: 1.2e-19. Score:
                     62.9. Matches aSDomain:
                     nrpspksdomains_KYK13_RS32380_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014399459.1"
                     /locus_tag="KYK13_RS32380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="oxidoreductase"
                     /protein_id="WP_223637676.1"
                     /sec_met_domain="adh_short (E-value: 1.9e-35, bitscore:
                     121.3, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="RmlD_sub_bind (E-value: 5.9e-05, bitscore:
                     21.1, seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSAPHETSRVWLITGSSRGLGRSFAEAVLEAGHRLVATARKPEQL
                     VALVERYGDRVRAVALDVTNPEQARAAVRTAVDAFGRLDVVVNNAGYGNLAPIEQVTDE
                     DFRSQLDTNLFGVMNVTRAALPVLRQQRSGHVIQVSSVGGRLSTPGLGAYQAAKWAVGG
                     FSEVLAKEVAPFGVKVTVLEPGGFRTDWAGASMTIADFLPEYAPTVGVVARNLRSRTGK
                     EAGDPKRAAQVLLQVAAMEQPPLHLVLGSDAFELSQQKLDALKAEDQTWKALSLSTDFP
                     DAHAPAPRS"
     aSDomain        complement(7315..7782)
                     /ASF="KR domain putatively catalyzing L-configuration
                     product formation"
                     /ASF="catalytic triad S,Y,N inconclusive"
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_KYK13_RS32380_PKS_KR.1"
                     /evalue="1.20E-19"
                     /label="KYK13_RS32380_PKS_KR.1"
                     /locus_tag="KYK13_RS32380"
                     /protein_end="165"
                     /protein_start="9"
                     /score="62.9"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="VWLITGSSRGLGRSFAEAVLEAGHRLVATARKPEQLVALVERYGD
                     RVRAVALDVTNPEQARAAVRTAVDAFGRLDVVVNNAGYGNLAPIEQVTDEDFRSQLDTN
                     LFGVMNVTRAALPVLRQQRSGHVIQVSSVGGRLSTPGLGAYQAAKWAVGGFS"
     CDS_motif       complement(7690..7782)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_KYK13_RS32380_0001"
                     /evalue="1.10E-04"
                     /label="PKSI-KR_m1"
                     /locus_tag="KYK13_RS32380"
                     /protein_end="40"
                     /protein_start="9"
                     /score="14.8"
                     /tool="antismash"
                     /translation="VWLITGSSRGLGRSFAEAVLEAGHRLVATAR"
     misc_feature    complement(7827..7844)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 15.49"
                     /tool="antismash"
     misc_feature    7836..7853
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 15.21"
                     /tool="antismash"
     gene            7906..8496
                     /locus_tag="KYK13_RS32385"
     CDS             7906..8496
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014399460.1"
                     /locus_tag="KYK13_RS32385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_223637678.1"
                     /transl_table=11
                     /translation="MAGDAQKTRQRLLEAAAAEFSEKGIAGARVDRIAAAAGCNKALIY
                     SYFGSKEQLFDAVFEAHVAEVARETPIDAADLPAYAGRLFDGFQARPQVLRLATWYELE
                     HGPTVAIPEPVARSNQHKAAAIAKAQKEGLVSKHFSADEVLALVLALSKTWAFPLSYCA
                     TATPPSPAELRRRRRAVVEAVRLLVTPVREEKA"
     gene            complement(8935..9894)
                     /locus_tag="KYK13_RS32390"
     CDS             complement(8935..9894)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1287: AraC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014399463.1"
                     /locus_tag="KYK13_RS32390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="AraC family transcriptional regulator"
                     /protein_id="WP_223637681.1"
                     /transl_table=11
                     /translation="MKTDVVSDVLETLRFKTLLFGRFELGAPWAVRLPRKANASFYVVA
                     RGSLRLQVEGTAKPVFLSAGDVVLLPRAPAHVLDDGSRRNPVASDDVPAQSLRPPTTRL
                     GGAGPLTTLITGCFQFGVDSAHPLLRTFPSIIRLSTQEGQGTPSLAATVQLITAETAMP
                     GAGSALVLGRLADVLLVHALRAQTALGGAKQAGWKALADPAIGHALSLMHEQPGAPWTV
                     ARLAQSVGVSRSGFAARFHALVGETPLHYLANWRMIRAARWLRESNDSVDTIAERAGYE
                     SAPAFSKAFKRRWGVGPGAYRRTSTEGNPADSVLTHDL"
     misc_feature    9904..9922
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 19.21"
                     /tool="antismash"
     gene            10001..10435
                     /locus_tag="KYK13_RS32395"
     CDS             10001..10435
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phenazine: phzB"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014399464.1"
                     /locus_tag="KYK13_RS32395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="WP_223637685.1"
                     /sec_met_domain="phzB (E-value: 5.9e-25, bitscore: 86.7,
                     seeds: 33, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDRTSPDLIRLMDAHLALIATDVEQWLALFDEHAVVEFPYAPSLG
                     GPSRLEGIDAIRAYFVPITKHFQGLTCTRLQRYTTTDPEVGWMEVHGAATLQPGNIPYE
                     QDYVMRVQVRDGRIVHYREYWNPLAAPQGTFESFAKEQQA"
     gene            10432..11280
                     /locus_tag="KYK13_RS32400"
     CDS             10432..11280
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1199: NmrA family
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014399465.1"
                     /locus_tag="KYK13_RS32400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="NmrA family NAD(P)-binding protein"
                     /protein_id="WP_223637687.1"
                     /transl_table=11
                     /translation="MTRILVIGAAGNTGRSITQGLTAEGFTVRTATREPRPPVAAAEHV
                     RFDWADPSTHGAALEGVDRMYALAPALVDDPSTLMLPVLEQGLAGGVRRVVLLSASIVP
                     EEGPGLGQVHHFLRTRAPEWSVLQPSWFMQNFAAPGHTHGASLRRDGTLVTATGHGRVG
                     FVDAEDIAAVGVRALADAKPHDTAHVITGPQALSHDDLAAILSRVSGRSIRHVHATPEE
                     ATRRHQDSGMPEAYARFLTMLDMRIRDGAEDRVTDTVQRVTGRPARDFESFARARLDVW
                     R"
     gene            complement(11245..11511)
                     /locus_tag="KYK13_RS32405"
     CDS             complement(11245..11511)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="KYK13_RS32405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_223637689.1"
                     /transl_table=11
                     /translation="MADGGGRPIESWAMGPEPKSSEREPGREAHGLLTGRPWDRTPFWV
                     KLPRMILGAVIALTAFIVIGVVGVGALGSDTDSTPDVQAGPGE"
     gene            11661..12995
                     /locus_tag="KYK13_RS32410"
     CDS             11661..12995
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1029: RND family
                     efflux transporter MFP subunit"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF008589.1"
                     /locus_tag="KYK13_RS32410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MdtA/MuxA family multidrug efflux RND transporter
                     periplasmic adaptor subunit"
                     /protein_id="WP_223637693.1"
                     /transl_table=11
                     /translation="MPTPPPPDTAPSSEVSSRPDGGETTSTEAPPPRRRHIRWGWLLLL
                     AGLVIAAIVAARAHRPHASGATAAGGHGGADGGAGAHGPKPVVTAEATTRDVPVSLVGL
                     GAVIPSASVTVRTRVDGQLMRVAFQEGQFVNAGDLLAELDPRPFQSQLEQARGQLMRDE
                     AYLENARLDLRRYTILVEQDSIARQQLDTQRALVRQYEGVVKADKGVVAAAEVNLIYTR
                     IIAPVPGRVGLRLVDPGNIVHAADTNGIVIVNTLQPIYVIFSVPEDNLPEILAKLNTHT
                     PLVVQAYDRSAQRLLATGALDTADNQVDPNTGTVRLKATFSNRDSRLFPQQFVNARLIV
                     DTLRGATVVPTAALQHGVQGTFVYVAQPDNTVSQRAVMTGPTDGDDTVITQGLRPGETV
                     VVEGADTLTNGSAIRRQHALGTGPGVGGGGAGGADGGPGAADGGR"
     gene            12995..16099
                     /locus_tag="KYK13_RS32415"
     CDS             12995..16099
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="resistance (resist) RND_efflux"
                     /gene_functions="transport (smcogs) SMCOG1049:
                     AcrB/AcrD/AcrF family protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002616567.1"
                     /locus_tag="KYK13_RS32415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="multidrug efflux RND transporter permease
                     subunit"
                     /protein_id="WP_223637695.1"
                     /transl_table=11
                     /translation="MSEPFILRPIATSLLMMALLLGGVLSYRLLPVSALPEVDYPTIQV
                     LTFQPGASPDVVASGVTAPLERQFGQMPGLNQMTSSSSSGASVITLQFTLQMSLDVAEQ
                     QVQAAINAANNLLPTDLPNPPIYNKVNPADTPVITLALTSDTVPLTQVEDLADTRIAQK
                     LSQLSGVGLVSISGGQRPAVRIQANGLALAARGLTLEDVRTAIAAANVNSPKGGFDGPR
                     QAYTLNSNDQRLSSAEYAPLIIAYRDGAPLRLSDVAHVFDGAENVRQAAWAGTTPAVIL
                     NVQRQPGANVIAVVDSVRKLLPQLQSTLPATVKVSVLSDRTTTIRASVRDVQRDLMFSV
                     ALVVLVIFLFLRNASATFIPSIAVPLSLVGTFAAMSLLGFSLNNLTLMALTIAAGFVVD
                     DAIVMIENISRYIEGGTPPLEAALRGSKQIGFTIVSLTVSLIAVLIPLLFMGDVVGRLF
                     REFAITLAVTILLSAVVSLTLTPMLCSRLLRRRPPEEANRFERAVGGAFDRLVGHYDVA
                     LTWVLGHRALTLLIAGVTLVLTGLLLYTIPKGFFPVQDTGVLQGISLGPQSISFSAMAE
                     RQQALARVVLEDPAVEGLSSFIGVDGTNTTSNSGRMLVTLKPLSERDASATEVIRRLQP
                     ALDGVPGISLALSPVQDLTLDSRVSRTQYQYSLSSPDAVALETWTQQLVNHLREQPELR
                     DVSSDLQNGGLRLNVILDRDTAARLGITALQVDDALYDAFGQRQVSTIFTQLNQYRVVL
                     EVPPSLQRVDTALKSVYLRSATGGAVPLASIASVTPGLGPLSINRQDQFPVANVSFNPA
                     PGVSLSQAVSAFNGVREKLHIPPSVQTAFAGTARTFQDSLRNEGFLVLAAVVVVYLVLG
                     VLYESYVHPLTILSTLPSAAMGALLALRVFGLELGMIALIGIILLIGIVMKNAIMMIDF
                     ALEAERLEGKAPRDAIHEACLLRFRPILMTTMASMLGAVPLALGGGIGGELRQPLGIAI
                     IGGLMVSQLLTLFTTPVIYLGFAGLSRRLQHLRRHSSPTAPRSPA"
     gene            16096..19197
                     /locus_tag="KYK13_RS32420"
     CDS             16096..19197
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="resistance (resist) RND_efflux"
                     /gene_functions="transport (smcogs) SMCOG1049:
                     AcrB/AcrD/AcrF family protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002616567.1"
                     /locus_tag="KYK13_RS32420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="multidrug efflux RND transporter permease
                     subunit"
                     /protein_id="WP_223637698.1"
                     /transl_table=11
                     /translation="MNPSALFIRRPVATSLLALGIALAGALAFRLLPVAPLPQVEFPTI
                     SVQAALPGASPEIMATSVATPLERQLGRIAGITQMTSSSNLGATSIVVQFDLSRNIDGA
                     ARDVQAAINAARGNLPSNLPNNPSYRKVNPADAPIMLLALTSPHRGRGALYDLGSTVLQ
                     QQVSQVTGVGQVLVGGGALPAVRAEVNPTTLEKYGLGLDAVRTALGAQNANRPKGQLED
                     GPRAYLLRADDQLIRAEQYRSLVIAYSNGAAVRLEDVAHVTDDNVEDVHSLGLANGKEA
                     IILIIFKEPGANVIDTVDALQARLPEFKAILPADVDLTVMMDRTTTIRASLRDVEMTLL
                     ISIGLVILVVFAFLGNLRATLIPSVAVPLSLLGTFAVMKLLGFSLDNLSMMALTISTGF
                     VVDDAIVVLEDIERHIEEGLSPMDAALRGAREVGFTVLSMSISLIAVFIPLLLMQGIVG
                     RLFREFAITLSVAILMSLVVSLTVTPTMCARLLRPKKPRRSRSAFHPFARLNAGYARSL
                     SWSLGHPVLLLLLTLAAIALSGYLFVVIPKGFFPQQDTGRITASIQAEQDISFAAMRQK
                     FTTYVRIIGEDPAVQAVAGSIGGSGPSGSSNAGTLFITLKPLEERKLSADAVIARLRGK
                     VMAVPGAMVYLQSAQDLVIGGRAGSAQYQYTLSSDTLPALNTWAPRVLARLQRVPGLLD
                     VNSDQRNHGLETNVVIDYDTAARFGLTAQQIDGVLYDAFGQRQVSTLYTSRNQYHVVMV
                     VLADFWQRPESLRRIYVTSATGQQVPLSAFARFVDAGTLLSVNHQGQFPSATVSFNLGP
                     GTSLGTVVTRIEAAVRELGLPSEVQGSFSGTAQAFQASLSSEPMLIAAALFAVYIVLGI
                     LYESLIHPITILSTLPSAGVGALLALLLFKLDLSIIALIGIILLIGIVKKNAIMMIDFA
                     LVSEREGHLGSRDAIFHAARLRLRPILMTTMAALLGALPLALGTGVGSELRRPLGIAIA
                     GGLCLSQLLTLYTTPVIYMTLDRMGRRVREWRARRFAPRGPGTA"
ORIGIN
        1 ggcgcgcgtg cagggggccc gcaaggacat ggacctgggc tacaccgacc gcatccgcct
       61 gtgggtggac ggcgatgagc gcgtgaagcg cgtcgtcgac gccgctcgcg acgaaatcgc
      121 ccgcgagacc ctggcctccg aaatccacgt gggcccgcag gggctcaccg gctcggagga
      181 ggaggccaac ctcaacggcc tcccggcgaa gctccgcgtc gagcgcgcct gaatcccgga
      241 cctccggaga gcagggaaag acagctccgg gtagacacct acccggggct ttgaatgcag
      301 acatcaggtg taccggcccg aggaccggga ggacgtgggc gcctcccggg acactcccgg
      361 cttgccgggt caggggacgc gtgttacgcg gacggccccc tgatttcgca aatcattctc
      421 aacatgccca tctcgttccg cagccgtccg ctccgcctgg tcccgggggc gctgcttggc
      481 gcctccctct ccgtcgtcgc agcgcctgcc ctggcacagg agcccgccgc gccccagacg
      541 tctccggctc cggagtcccc ggcccccgcg caggctccga atccggagtc atccgccgcc
      601 gcgcccgggg acgacgaggt cttcgacctg cccacggtga cggtggagag cgagcgcgcc
      661 acaggcccgg tgcggggcta caccgcgcgc cgcagcgcga gcgggacgaa gacggacacc
      721 gcgattgtcg acacgccgca gtcggtgtcg gtggtgggcc gggagcagat ggacgcgcag
      781 caggcgcaga ccgtgatgga ggccacgcgc tacacgccgg gcgtgcgctc ggacacgttc
      841 ggcgcggatc cgcgcaacga ctggttcctc attcgcggct tcacgtcgca ggaggccggc
      901 tacttcctgg acgggctcca gctgtactcc agcagcttcg ccacctggcg catcgagccc
      961 ttcggcctgg agcgcgtgga ggccgtgcgc ggccccgcct ccgtgctgta cggcggcacg
     1021 tctccgggcg gcctgctcga catggagggc aagcgtccgc cggtggaagg ctccgtgcgg
     1081 cacgtggagg tgggcggcaa cacgttcgcc aacggctacg cggccgtgga cttcggcggc
     1141 gccatcgacc cgggcaacca ctggcgctac cgggtggcgg cgctggcgcg cggcggtggc
     1201 acgcaggtgg atgagacgga caacaaccgc ctgttcatcg cgccggccct cacctgggcg
     1261 ccgtcggaga acacctcgct gacgctgcac ggcagcttcc tggcggaccg cacgcagggg
     1321 cagaacttcc tgccgtacgt gggcaccgtg gtggacgcgc cctatggccg catccccacc
     1381 gacctcttca ccagtgacaa gagcctggac cacttccagc gcaaccagtc ctgggcgggc
     1441 tacgagttct cccaccgctt caacgacacc ttcacgctgc ggcagaacct gcgcttcgcg
     1501 cacctggacc tggacttcca gacgctctac ggcgtgggct accagggcga gccggcggac
     1561 gcgcagctct cccgcggcaa cttcgtcacc cggccgcgcg cgaacctctt cacggtggac
     1621 acgcagggcg aggcgcgctt ctccaccggc cccgtgcgcc acacggtgct ggcgggcgtg
     1681 gacttcaaga actaccgcct ggacgacgaa cagggctacg aggcgggtgc accgctggat
     1741 ctgctcaacc ccgtgcgcgg cgactacacg cccacggaga cgcgctacac gctgggccgc
     1801 tccacgcagg accagctggg cgtctacctc caggaccagc tgcgcttcgc ggaccggctg
     1861 agcctgacgc tgagcgggcg tcatgactgg gtggggatgg acgtggacaa caagctcttt
     1921 cccacctcca gctacgaggg cagcgagagc gccttcagcg gtcgcgcggg cctgctctac
     1981 cacttcgact tcggcctcgc gccgtacgtg agctactcga agtcgttcaa cccggtggcg
     2041 gggacgaagt cggacggctc gctgttcgag ccggagaagg gccagcagct cgaagcggga
     2101 gtgaagtacc agccagatgc gttcccggtg ctggtaggcc tgtcggtgtt cgagctgaag
     2161 cgaaagaact tcgtgaccac ggacggcgcc ttcaaccagc tgcagattgg cgaggtccgt
     2221 tcgcgaggct tcgaggtgga ggccaacgcc acgctgatcc acgggttgag cctggttggc
     2281 tccgcgtcgt tctactcgct ggagatcacc gagggcgcgg acttcgaact gggcaagcgt
     2341 ccggtgggtg tgccggaggt gctggcgtcg ctgtggctgg actacacctt ccaggacgga
     2401 gcgctgcgcg gcttcggcgc ggcggcgggc gtgcgcggcg tgggcagctc ctacgcggat
     2461 cgcgagaaca cgctggacgt gccgggcttc acgctggtgg acgccaacgt gcactacgag
     2521 cgcggcccgt ggcgcgcggc catcaacgcc tccaacctgg gagacaggac ctacgtgtcc
     2581 tcgtgcagct ccgcgacggc ctgcttctac ggcgagcgcc gccgcgcgtc cgccacggtc
     2641 ggctacacct ggtagtcgag acacacgagt gaaaggccct ttcgctggga gggcctgaag
     2701 ccatccccca ccgcggcacc catggggccc gcacctggca cggcttccgc cagcaagggc
     2761 ctcacatcat gcccggccgc cacgtctcgg aacgccggaa gcgtcacggt caaacgttga
     2821 cgagacgcct ctcccagccc agtccctcgg acacgaaagg cgttcccatg ggtgagaagc
     2881 cgagaacccg gccaggacgc ccccgtcgga ggcgcggcac caaaacctgt ccgactgtcg
     2941 gacacgtttg gacgatggcg gcggcctccg agggcggatg aaatcctccg accgacctcg
     3001 tcatccatcg tggctcgggg cgcgccgctc tggccgggca acgaaccgaa acctgtccga
     3061 ctgtccgaca ggttctgcga gcccgctccg gggaaggccg ccccagcagc acgaacctgt
     3121 ccgacaagtg cggaagcccg tgacaaaaga gggaccacag ggccagccgg accgcacgaa
     3181 cccgtccgac tgtcggacaa gttttgaagc ccactcaggg aggaccgtcc ccagcagccc
     3241 gaacctgtcc gactgtccga caggtttcga agcccacggt gatggggtcc accgccccgc
     3301 ccaagccaca tgaacccgtc caactgttca acaggttggg aagtccatgg cgaggggggc
     3361 caccgcgccg cccaggccgc atgaacccgt ccaactgttc aacaggttgg gaagtccatg
     3421 gcgagggggg ccaccgcgcc gcccaggccg catgaacctg tccgaccgtc tgacaagttt
     3481 gcccgtccgt ggcgaggggc ccttcatcgg cgccgtgggg acctgtccaa ctgtcggaca
     3541 ggtctggaag tgcccgcggc gcacggccct tcctcccaga ccgaggaaac cagcccggac
     3601 tgtcggacag gtttggaagt ccgtggcgca cgggcccttc ctcccgggca gagggaacct
     3661 gtccgactgt cggacaggtc ttgaacgtcc gcaccaagga ggagccactg ctccgcctgg
     3721 gcagcagaac cggtccgacc gtccgacagg ctttgagtgt ccgtggaagt ggactccgct
     3781 ctgcccggac agcagaaccg gtccgactgt ccgacaggtt cagaagtccg tggcgcggga
     3841 gttccactcc gcccggacag tagaaccggt ccgactgtcc gacgggtttg gaagtccgtg
     3901 gcgcgagagc tccactccgc ctgggcggct gaagccggtc cgactgtccg acgggttcgg
     3961 aactccgtgg cgcggggcct cgctccgcac gggtagcgga agccggtccg attgtcggac
     4021 aggttttgga ggcccgccgc gacagggctg ccgcctcatc cgacctgcac gaacttgtcc
     4081 gactgtcgga caggttttgg acgaccgcac ccagggggcc cgcctcggat agaggcgagg
     4141 tggatcgcat ggtcatccgg gggcctggcg cacatcgtgc acttcgggcc tcaagccgcg
     4201 cgctgctggg aagtccgtcg ggtgcctcgc cgcgcttcgt gactgctcgg ccttacgcct
     4261 tgacgagggg gccttcgggc gcggcgccac caggcacggg ctccgctgtc ttcctcctgc
     4321 gcaggcccca cgcgagcccg ccgcagccaa gcgccatgga ggccaggaat gcctccgcca
     4381 cgaacacccg gggcaagccg cgcgacagcg ccgtgaacag gttcacgtcc tgcgtcagga
     4441 cgtcgcccac cacgaccgta ccgaacagca ccgcggccac ggcgctcagc acgctgccca
     4501 cccggcgcga tgacccgcgc ggcacgagcg cgatgaccac cccgagcgcc cacgcgccca
     4561 ggaagacgcc gaactcccag tctcctcgcc gcgccagcgt ccacggcagc acgcggttcg
     4621 cggcgcagta caccgccgtg ccggacacga gcccggcgga tacacctacc gtcagccgct
     4681 ccagcactcg gttcccacgg cgcgtgcgca gtgggtctcg gcgctccagc cagatgaggt
     4741 tgccggtgat gagcaccgcg cacatcgcca gcgcgagcaa cgcgtagagc ggcttcatca
     4801 actcctccgc gaaccggccc gcgtgcaggt cgaagagcag ccgctccacc gtgaagttcg
     4861 gcgtgcgcga ctccacgctc gacccgaacg tctcccccgt caccgtatcc acatgcgtga
     4921 aatggtccgg ccccagtggc gacaactgga agtacacgcc cgcccaggcc ttcgcatctc
     4981 cgtagtcatg aagctccacg tagcggggcg tcccctccgc tccgggcacc gacgcgcgcg
     5041 cacggtccac caccgtgtcc agggaaagca tgggcgcgtc ctgcttcgcc gcttcacgca
     5101 cgggcgtgct gtagccgcga agctgcgtca cccggtccgc ctgcccccgg tacaccgtgc
     5161 tcccgaatcc ctgcgccgcc agccccgcca ggcacagcac cgcgcccgtc cacgccagca
     5221 tcgcggtgaa cggcagcccg aagacgccca gcaccttgtg cgcgtccgac gcggagaagc
     5281 gcggcttcgc cgtgtgccgg aaacgccacc actgcgtgcg caggtccttc aggtggatcc
     5341 acaggccgct gaccagcgcc accaggagcg ccaccgatac caggcccgtc agctccatgc
     5401 cccagggcac ccgatagaag aagtgcatcc agtacagctc gctcgccagc cggctgcgct
     5461 cgggcagcgc ggtgccggtg agcggatcca gccacagcac gcgcatcccc gtgggctcga
     5521 agaggtacgc ggtgatgaac cgcgtctcct cgtgcgtgag caggcccacg tgagcgcctc
     5581 gcggcaacgg cccccgctcc cgcacgcgcg cgagcatcgc gtcgaacgac ggcggtgact
     5641 ccgagggcgg cgcgacgtgg agcgcgggct cctgccacac ctccagctcc tcgcggaaca
     5701 tggcgaagac gccgcagaag aagatgacga acaggaacag gctggcgacg acaccggccc
     5761 acgcatgcag gtcgaactgg atgcggaacg tccggggcga cagcttcatc gcggcccccg
     5821 cagcaacagg gccacggcca ccggcagcac caccgccaga cacacgcccc acgccacccg
     5881 accactccgg gtcagcggca gcgcgcacgc gagccccacc cacacgggca gcaccgcctg
     5941 gaagcccagc acgaaggccc acggcccgga caccggcagg aaggccatca ccgccgcccc
     6001 cgccgcgaac gccgccagcg gcgcccccag cacgaccgcc agcgtgcgcg ccaccgagtg
     6061 gttcgccgcc ttgtctgcgc gcccctcgct catcgggcca cgcccatcag cgccaccggc
     6121 accaatcccg ccacgccgct cacccacgcg aaggtgcgcg cacgggaggg ccggggcgcc
     6181 agcaccagca ccagccccga ggccgccgtc atcgccagga cgcccaacac cagcagcccc
     6241 gccacccacc cgaaatcacc cacgcagcac gccatcgacg cgagccccgg cacggccgca
     6301 ccccaccgcg ctcggccgcc cgcgcccatc cacgacaccg ccgacacgca gaagcacagc
     6361 gcggcgaggc tcagcatcgc ggccaccgcg cgaccccatc tcttggctca aagttgataa
     6421 tgatttgcat cctcacgaga gcccccgggc gtgtcaaggc aggcgagagg gccccatgct
     6481 cgcggtgcga gcgtcggcgc acgaacaccg tccgcgcccc ccgcttccag gaaatgtcgt
     6541 gcgctggata atggcgggat gaccggaacc cagtccctga agggaagctg tcactgcgga
     6601 gcgacgcggt tcgaggtggc cgcgccgccc aaggacatca cccgctgcaa ctgcacgttc
     6661 tgctccaagc gcggtgtgct ctgggcctac tacgcgccag agcacgtgac gttcacgcgc
     6721 cgggagaacg tgggcaccta cgcgcgcaac gagcccgtgg tgcaccacca ctgcgagcag
     6781 tgcggctgcg gcacgtggac ggacattccc gtctgggaga acaacgcacc tgtgcccggc
     6841 aggttcaagg tgggcctcaa cgcgcgcctg ttcgacgact tcgacctgga cgcggtgcgc
     6901 gtggtgttcg tggacggccg caacctctgg tagccgtcac gagcgtggag ccggggcgtg
     6961 ggcgtccggg aagtcggtgg acagcgacag ggccttccac gtctggtcct ccgccttgag
     7021 cgcgtccagc ttctgctgcg acagctcgaa cgcgtcgctg cccagcacca ggtgcagcgg
     7081 cggctgctcc atcgccgcca cctggagcag cacctgggcc gctcgtttcg gatcccccgc
     7141 ctccttgcct gtgcgcgaac gcaagttccg cgcgaccacg cccaccgtgg gcgcgtactc
     7201 cggcaggaag tccgcgatgg tcatggacgc gcccgcccag tccgtgcgga agccgcccgg
     7261 ctccagcacc gtcaccttca cgccgaaggg ggccacctct ttcgccagca cctcggagaa
     7321 gcctcccacc gcccacttcg cggcctggta cgcgcccagc cctggcgtgg acaggcgccc
     7381 tcccacggac gacacctgga tgacgtgccc ggagcgctgc tgacgcaaga cgggcagcgc
     7441 ggcgcgtgtg acgttcatga cgccgaagag gttcgtgtcg agttgcgagc ggaagtcttc
     7501 gtccgtgacc tgctcgatgg gcgcgaggtt gccgtagccc gcattgttca ccaccacgtc
     7561 caggcggccg aacgcatcca cggcggtccg gaccgcggcc cttgcctgct cggggttcgt
     7621 cacgtccagg gccaccgcac ggacccggtc cccgtaacgc tccaccagcg cgaccagctg
     7681 ctccggcttg cgcgcggtgg ccaccagccg gtgcccggcc tccaatacgg cctccgcgaa
     7741 gctgcgcccc aggcctcggg aagagccggt gatgagccag acgcgggacg tctcatgggg
     7801 agcactcatg gcgggattcc tctcaactaa ctggttggtt acatggatat aaacggcgac
     7861 ctctcccggt gcaacctgga gtgggctgag gcatgttggg gtggcatggc tggcgacgcg
     7921 cagaagaccc ggcagcgcct cttggaggcg gccgcggcgg agttctcgga gaagggcatc
     7981 gcgggcgcgc gcgtggaccg catcgcggcg gcggccggct gcaacaaggc gctcatctat
     8041 tcgtacttcg gcagcaagga gcagctgttc gacgcggtct tcgaggcgca cgtcgcggag
     8101 gtggcgcgcg agacgcccat cgacgctgcg gacctgcccg cctacgcggg gaggctgttc
     8161 gacggcttcc aggcccgccc acaggtgctg cgcctggcca cctggtacga gttggagcac
     8221 ggccccacgg tggccatccc ggagccggtc gcgcgcagca accagcacaa ggcggccgcc
     8281 atcgcgaagg cgcagaagga ggggctggtg tccaagcact tctcggcgga tgaggtgctc
     8341 gcgctcgtgc tggcgctctc caagacgtgg gccttcccgc tgtcgtactg cgccacggcc
     8401 accccgccct cgccggcgga gctccgcaga cggcgccgcg ccgtcgtgga ggcggtccgg
     8461 ttgctggtga cgcccgtccg ggaggagaag gcctgagccg gacccgcctc cgttcgcggt
     8521 gaacgtcgtg ccgtcgccgt acagcagcgc ccgcgacccg tccgcggtgc aggcgagcgt
     8581 gtccacgcgg cgggtgcccg cgctcagcga tacagggagg gtgaacgcgg acgcgcagct
     8641 tcgcgcctgg cccgcaagtg aaggcctgtt tcgtgtacgc cccactcggg cacggacagc
     8701 tacttgtcgt gggcccgggc ggaggccttg aacttcgcca gcgctggccc gccttccccc
     8761 acctacgcca cgagcccaac tgccacagcg gctccgccga cacggtcagc ccccgcgcac
     8821 ggcgtggaca tcaggaccag tgaggaggtg acggagtagg acaagcgcgg gaggcgcggc
     8881 tgcatggggg gacgctcccg gagaggaggc aaggcatttc caacgcccca ggagctacaa
     8941 atcatgggtc aacacggagt ccgctggatt cccctcggtt gacgtgcgcc gatacgcgcc
     9001 ggggcccacg ccccagcggc gcttgaaggc cttgctgaag gcgggcgcgc tctcatagcc
     9061 ggcgcgctcg gcgatggtgt ccacgctgtc gttggattca cgcagccagc gcgcggcgcg
     9121 gatcatccgc cagttggcca ggtagtgcag gggcgtctct cccaccagcg cgtggaagcg
     9181 cgcggcgaaa ccggagcggg acacgcccac ggactgcgcc agccgcgcca ccgtccacgg
     9241 cgcgccgggc tgttcgtgca tcagcgagag cgcgtggcca atggccggat ccgccagcgc
     9301 cttccacccc gcctgcttcg cccccccgag cgccgtctgg gcccgcagcg cgtgcacgag
     9361 cagcacgtcc gccagccggc ccagcaccag cgcgctcccc gcgcccggca tggcggtctc
     9421 cgcggtgatg agctgcacgg tggcggcgag cgaaggcgtc ccctgcccct cctgcgtgga
     9481 caggcggatg atggagggga aggtccgcag cagcggatgc gcggagtcca cgccgaactg
     9541 gaagcagccg gtgatgagcg tggtgagcgg ccccgcaccg cccagccgcg tggtgggcgg
     9601 acgcagcgac tgcgccggga catcgtcgct cgcgacgggg ttgcggcggc tgccgtcatc
     9661 cagcacgtgc gcgggggccc ggggcagcag caccacgtca ccggcggaaa ggaacaccgg
     9721 cttcgccgtg ccctccacct ggaggcgcag gctcccgcgc gccaccacgt agaaggatgc
     9781 attggccttg cggggcaggc gcaccgccca gggtgcgccc agctcgaagc ggccgaagag
     9841 cagcgtcttg aaccgcagcg tctccagcac gtcggagacc acgtcggtct tcacgtccgg
     9901 aggcattgga cggaaagaca gttcttttgg acgcagtggc atggagcgtc cataacgggc
     9961 ggcctatccc tggtccatct cctctcgctg gaggccgtac atggaccgca cctcccctga
    10021 cctcatccgg ctgatggacg cgcacctggc gctcatcgcc acggacgtcg aacagtggct
    10081 cgccctgttc gacgagcacg ccgtcgtcga gttcccctat gccccctcgc tcggtgggcc
    10141 ttcacggctg gagggcatcg acgccatccg cgcctatttc gtccccatca cgaagcactt
    10201 ccaggggctc acctgtacgc gcctccagcg ctacaccacc acggaccccg aggtgggctg
    10261 gatggaggtc cacggcgcgg cgacgctgca gcccgggaac atcccctacg aacaggacta
    10321 cgtgatgcgc gtgcaggtgc gcgacggccg catcgtgcac taccgcgaat actggaaccc
    10381 gctggccgcg ccccagggca ccttcgagtc cttcgcgaag gagcagcagg catgacgcgc
    10441 atcctcgtca ttggcgcggc cggcaacacg gggcgctcca tcacacaggg cctcacggcc
    10501 gagggcttca cggtgcgcac cgccacgcgc gaaccgcggc cgcccgtcgc cgccgccgag
    10561 catgtgcgct tcgactgggc ggatccgtcc acacacgggg ccgcgctgga gggcgtggac
    10621 cgcatgtacg ccctggcccc cgcgttggtg gacgacccgt ccaccctcat gcttcccgtc
    10681 ctggagcagg ggctggccgg cggcgtgcgg cgggtcgtcc tgctctccgc gtccatcgtc
    10741 ccggaggaag ggccgggcct gggccaggtg caccacttcc tgcgcacgcg cgcgccggag
    10801 tggagcgtgc tccagccctc gtggttcatg cagaacttcg ccgcccccgg ccacacgcac
    10861 ggcgccagcc tccgccgcga cgggacgctg gtgacggcca cggggcatgg gcgggtgggc
    10921 ttcgtggacg cggaggacat cgcggcggtg ggggtcagag cgctcgcgga cgcgaagccg
    10981 cacgacaccg cgcacgtcat caccggcccc caggcgctga gccatgacga cctcgcggcc
    11041 atcctgtccc gggtgtcggg ccgctccatc cggcacgtgc acgcgacgcc cgaggaggca
    11101 acacggcgcc atcaggactc cggcatgccg gaagcctacg cgcgcttcct cacgatgctc
    11161 gacatgcgca tccgcgacgg agcggaggac cgcgtgacgg acaccgtgca gcgggttacc
    11221 ggccggcccg cgcgggactt cgagtcattc gcccgggccc gcctggacgt ctggcgttga
    11281 gtccgtgtcc gagccaaggg cgcccacgcc cacgacaccg atgacgatga acgccgtcag
    11341 cgcgatgacg gcgccgagga tcatcctcgg cagcttcacc cagaagggcg tgcggtccca
    11401 cgggcgcccc gtcaggaggc cgtgtgcttc gcggccgggc tcgcgctcgg aggacttcgg
    11461 ctcggggccc atggcccatg actcgatggg ccttccgccg ccgtccgcca tcgcgcgcac
    11521 tccccctggc ccatggagga cgtccgctgg agggcagccc cccctccctt cggactggtt
    11581 gagggcgctc gcgacaagac acacgttggg ggccccgaaa cagcggctcc tcctcggtgg
    11641 gttccctggc ggtccttcgc atgcccacgc ctcctcctcc cgatacggcc ccctcttcgg
    11701 aggtgtcgtc gcggcccgac ggaggggaga ccacgtcaac cgaggccccc ccgccccggc
    11761 gccgccacat ccgttggggc tggctcctgc tgctcgctgg tctggtcatc gcggccatcg
    11821 tcgcagcgcg ggctcaccgt ccccacgcct ctggggccac ggccgcgggt gggcatggcg
    11881 gcgcggatgg aggcgcgggc gctcatggcc ccaagcccgt ggtgacggcc gaggcgacga
    11941 cgcgcgacgt gccggtatcg ctcgtgggcc tgggcgcggt gatcccttcc gcatccgtga
    12001 ccgtgcgcac ccgggtggat ggacagctca tgcgcgtggc cttccaggag ggccagttcg
    12061 tcaacgcagg cgacctcctg gcggagctcg acccgcgccc cttccagagc cagttggagc
    12121 aggcccgcgg ccagctcatg cgcgacgagg cgtacctgga gaacgcccgg ctggacctgc
    12181 gccgctacac catcctcgtg gagcaggact ccatcgcgcg ccagcaactg gacacccagc
    12241 gcgcgctcgt gcgccagtac gagggcgtcg tgaaggcgga caagggcgtg gtcgccgccg
    12301 ccgaggtcaa cctcatctac acacgcatca tcgcgcccgt ccccggccgc gtcggcctcc
    12361 ggctcgtcga ccccggcaac atcgtccacg cagcggacac gaacggcatc gtcatcgtca
    12421 acaccctgca gcccatctac gtgatcttct ccgtgccgga ggacaacctg ccggagatcc
    12481 tggcgaagct gaacacgcac acgccgctcg tcgtccaggc ctatgaccgc agcgcccaac
    12541 gcctgctggc caccggcgcc ttggacaccg cggacaacca ggtcgacccc aacaccggca
    12601 ccgtgcggct caaggcgacg ttctccaacc gcgactcgcg gctgttcccc cagcagttcg
    12661 tcaacgcgcg gctcatcgtc gacacgctgc gcggcgccac ggtggtgccc accgcggcgc
    12721 tccagcacgg cgtccagggg acgttcgtct atgtcgcgca gcccgacaac accgtcagcc
    12781 agcgcgcggt gatgacgggc ccgacggacg gcgacgacac cgtcatcacc cagggcctgc
    12841 ggccggggga gaccgtggtc gtggagggcg cggacaccct caccaacggc tccgccatcc
    12901 ggcgccagca cgccctgggc acgggccccg gagtgggtgg cggcggagcc ggaggcgccg
    12961 acggcggccc gggggcggcg gacggtgggc gctgatgtcc gaacccttca tcctgcggcc
    13021 catcgcgacg tccctgctga tgatggccct gctcctgggc ggcgtgctgt cgtaccgcct
    13081 gctgcccgtg tccgcgcttc cggaggtgga ctaccccacc atccaggtcc tcaccttcca
    13141 gcctggcgcg agcccggacg tggtggcctc cggcgtcacc gcgcccctgg agcggcagtt
    13201 cgggcagatg ccaggcctca accagatgac gtcgtccagc tccagcggcg cgtccgtcat
    13261 cacgctccag ttcacgctcc agatgagcct ggacgtcgcg gagcagcagg tccaggccgc
    13321 catcaacgcc gccaacaacc tcctgcccac cgacctgccc aacccgccca tctacaacaa
    13381 ggtcaacccc gcggacacgc ccgtcatcac cctggccctc acctccgaca ccgtgccgct
    13441 cacccaggtg gaggacctgg cggatacgcg catcgcgcag aagctctcac agctgtccgg
    13501 cgtggggctg gtgagcatca gcggcggcca gcgccccgcc gtccgcatcc aggccaacgg
    13561 gctcgcgctg gccgcgcggg gcctgacgct ggaggacgtc cgcaccgcca tcgccgccgc
    13621 caacgtgaac agccccaagg gcggcttcga cggcccccgc caggcctaca ccctcaactc
    13681 caatgatcag cgcctgtcga gcgcggagta cgccccgctc atcatcgcgt accgcgacgg
    13741 cgccccgctg cgcctgtccg acgtggcgca cgtcttcgac ggcgcggaga acgtacgcca
    13801 ggccgcctgg gccggcacca cgcccgccgt catcctcaac gtgcagcgcc aaccgggcgc
    13861 caacgtcatc gccgtcgtgg acagcgtccg caagctgctg ccccagctgc agtccaccct
    13921 gcccgcgacg gtcaaggtgt ccgtgctcag cgaccgcacc accaccatcc gcgcctccgt
    13981 gcgcgacgtg cagcgcgacc tgatgttctc cgtcgcgctc gtcgtgctcg tcatcttcct
    14041 cttcctgcgc aacgcctccg ccaccttcat ccccagcatc gcggtgccgc tgtcgctggt
    14101 gggcaccttc gccgcgatgt cgctgctggg cttctccctc aacaacctga ccctgatggc
    14161 gctcaccatc gccgcgggct tcgtcgtcga cgacgccatc gtgatgatcg agaacatcag
    14221 ccgctacatc gaaggcggca cgccgcccct ggaggccgcg ctcaggggct ccaagcagat
    14281 cggcttcacc atcgtctccc tcacggtgtc gctcatcgcc gtgctcatcc ccctgctctt
    14341 catgggggac gtggtggggc gcctgttccg cgagttcgcc atcaccctgg ccgtgaccat
    14401 cctgctgtcc gcggtcgtgt ccctgaccct cacgcccatg ctctgctcgc ggctgctgcg
    14461 ccggcgcccg cccgaagagg ccaaccgctt cgagcgcgcc gtgggcggcg cgttcgaccg
    14521 cctggtgggc cactacgacg tcgcgctcac gtgggtgctg ggccaccgcg cgctgacgct
    14581 gctcatcgcc ggggtgacgc tcgtgctcac cggcctgctc ctctacacca tccccaaggg
    14641 cttcttcccc gtgcaggaca ccggcgtgct gcagggcatc tccctggggc cccagtccat
    14701 ctccttctcc gccatggcgg agcgccagca ggccctggcc cgggtggtgc tggaagaccc
    14761 ggccgtggag gggctgtcgt cgttcatcgg cgtggatggc accaacacca catccaacag
    14821 cggccggatg ctcgtcaccc tcaagccgct gtcggagcgc gacgcctccg ccacggaggt
    14881 catccgccgc ctccagccgg cgctggacgg cgtgcccggc atctccctgg ccctgtcacc
    14941 cgtgcaggac ctcacgctgg acagccgcgt gagccgcacc cagtaccagt acagcctcag
    15001 ctcgccggac gccgtggcgc tggagacctg gacccagcag ctcgtcaacc acctgcgcga
    15061 gcagcccgag ctgagggacg tctccagcga cctgcagaac ggcggcctgc ggctcaacgt
    15121 catcctggac cgggacaccg ccgcccggct gggcatcacg gccctgcagg tcgacgacgc
    15181 cctctacgac gccttcggcc agcgccaggt gtccaccatc ttcacccagc tcaaccagta
    15241 ccgcgtggtg ctggaggtgc cgccctcgct ccagcgcgtg gacaccgccc tgaagtccgt
    15301 ctacctgcgg tccgccaccg gcggcgccgt gcccctcgcg tccatcgcca gcgtgacgcc
    15361 gggcctgggg ccgctcagca tcaaccggca ggaccagttc cccgtcgcca acgtctcctt
    15421 caaccccgcg cccggcgtgt cgctgtccca ggcggtgagc gccttcaacg gggtgcggga
    15481 gaagctccac atcccccctt ccgtgcagac cgccttcgcg ggcaccgcgc gcacgttcca
    15541 ggactcgctc aggaacgagg gcttcctcgt gctggcggcg gtggtggtcg tctacctggt
    15601 gctgggcgtg ctgtatgagt cctacgtcca cccgctcacc atcctgtcca cgctgccgtc
    15661 cgcggccatg ggcgcgctcc tggcgttgag ggtgttcggg ctggagctgg ggatgatcgc
    15721 cctcatcggc atcatcctgc tcatcggcat cgtgatgaag aacgccatca tgatgatcga
    15781 cttcgcgctg gaggcggagc gcctggaggg caaggccccc cgggacgcca tccacgaggc
    15841 gtgcctcctg cgcttccgtc ccatcctgat gaccacgatg gcgtccatgc tgggcgccgt
    15901 gcccctggcg ctcggcggag gcattggcgg agagctgcga cagcccctgg gcatcgccat
    15961 catcggcggg ttgatggtca gccagctgct gacgctcttc accacgccgg tcatctacct
    16021 gggcttcgcg gggctgtcgc gccggctcca gcacctgcgg cggcactcct cccccacggc
    16081 gccgcggagc ccggcatgaa cccctccgcg ctcttcatcc ggcgccccgt ggccacgtcg
    16141 ctgctggcgc tgggcatcgc gctggcgggg gcgctggcct tcaggctcct gccggtcgcg
    16201 ccgctgcccc aggtggagtt ccccaccatc agcgtgcagg cggcccttcc gggcgcgagc
    16261 ccggagatca tggccacgtc ggtcgcgacg ccgctggagc ggcaactggg acgcatcgcg
    16321 ggcatcaccc agatgacgtc gtccagcaac ctgggcgcca ccagcatcgt cgtgcagttc
    16381 gacctgtcgc ggaacatcga cggggcggcg cgcgacgtcc aggccgccat caacgccgcc
    16441 cggggcaacc tgccttcgaa cctgcccaac aacccctcct accggaaggt gaaccccgcg
    16501 gacgcgccca tcatgctgct ggcgctcacc tcgccccacc ggggccgcgg cgcgctctat
    16561 gacctggggt ccaccgtcct ccagcagcag gtgtcccagg tgacgggcgt gggacaggtg
    16621 ctggtgggcg ggggcgcgct gcccgcggtg cgcgcggagg tgaaccccac cacgctggag
    16681 aagtacggcc tggggctgga cgcggtccgc accgcgctgg gcgcgcagaa cgccaaccgc
    16741 cccaagggcc agctggagga cgggccccgg gcctacctgc tgcgcgcgga tgatcagctc
    16801 atccgcgcgg agcagtaccg gtcgctcgtc atcgcctact ccaacggcgc cgccgtgcgg
    16861 ctcgaggacg tggcccacgt caccgacgac aacgtggagg acgtgcacag cctggggctc
    16921 gccaatggca aggaggccat catcctcatc atcttcaagg agccgggggc caacgtcatc
    16981 gacacggtgg atgcgctcca ggcgcggctc cccgagttca aggccatcct gcccgcggac
    17041 gtggacctga cggtgatgat ggaccgcacc accaccatcc gcgcgtcgct gcgcgacgtg
    17101 gagatgacgc tgctcatctc catcgggctg gtcatcctgg tggtgttcgc cttcctgggc
    17161 aacctgcgcg ccacgctgat ccccagcgtc gccgtgccgc tgtcgctgct gggcaccttc
    17221 gcggtgatga agctcttggg gttcagcctg gacaacctgt ccatgatggc gctcaccatc
    17281 tccaccggct tcgtggtgga tgacgccatc gtcgtgctgg aggacatcga acggcacatc
    17341 gaggaaggcc tgtcccccat ggacgcggcg ctgcgcggcg cgcgcgaggt gggcttcacc
    17401 gtgctgtcga tgagcatctc cctcatcgcc gtcttcatcc ccctgctgct catgcagggc
    17461 atcgtgggcc ggctgttccg cgagttcgcc atcacgctgt cggtggccat cctcatgtcg
    17521 ctggtggtgt cgctcaccgt gacgcccacc atgtgcgccc ggctgctgag gcccaagaag
    17581 ccccggcgct cgcgctccgc cttccacccc ttcgcgcggc tgaacgcggg ctatgcccgc
    17641 agcctgtcct ggtccctggg gcacccggtg ctgctgctgc tgctcacctt ggccgccatc
    17701 gcgctcagcg gctacctgtt cgtggtcatc cccaaggggt tcttcccgca gcaggacacc
    17761 ggccgcatca ccgccagcat ccaggcggag caggacatct ccttcgcggc gatgcgccag
    17821 aagttcacca cctacgtgcg catcatcggc gaggacccgg ccgtccaggc ggtggcgggg
    17881 tccattggcg gctccggccc cagcggctcg tccaacgcgg gcacgctgtt catcacgctc
    17941 aagccgctgg aggagcgcaa gctgtccgcg gacgccgtca tcgcgcggct ccggggcaag
    18001 gtgatggccg tgcccggcgc catggtgtac ctccagtccg cgcaggacct ggtgattggc
    18061 gggcgggcgg gcagcgcgca gtaccagtac accctgtcct cggacacgct gccggcgctg
    18121 aacacgtggg cgccgcgggt gctggcgcgg ttgcagcggg tgcccgggct gctggacgtc
    18181 aacagcgacc agcgcaacca cgggctggag accaacgtcg tcatcgacta cgacacggcg
    18241 gcccgcttcg gcctcaccgc ccagcagatc gacggcgtgc tgtatgacgc cttcggccag
    18301 cggcaggtgt ccaccctgta caccagccgc aaccagtacc acgtggtgat ggtggtgctg
    18361 gcggacttct ggcagcggcc ggagagcctg cgccgcatct acgtgacgag cgccaccggc
    18421 cagcaggtgc cgctgtcggc gttcgcccgc ttcgtggacg cgggcacgct gctgtccgtc
    18481 aaccaccagg gccagttccc gtccgcgacg gtgtccttca acctggggcc ggggacgtca
    18541 ctggggaccg tggtcacccg cattgaagcc gccgtgcgcg agctgggcct cccctcggag
    18601 gtgcagggca gcttcagcgg cacggcccag gcgttccagg cctcactgtc ctccgaaccc
    18661 atgctcatcg ccgcggccct gttcgccgtc tacatcgtgc tgggcatcct ctacgagagc
    18721 ctcatccacc ccatcaccat cctgtccacg ctgccgtccg cgggcgtggg cgcgctgctg
    18781 gccctgctgc tgttcaagct ggacctgtcc atcatcgcgc tcatcggcat catcctgctc
    18841 atcggcatcg tgaagaagaa cgccatcatg atgatcgact tcgcgctggt gtcggagcgc
    18901 gagggccacc tgggttcacg cgacgccatc ttccacgccg cccggctgcg gctgcgcccc
    18961 atcctgatga cgacgatggc ggcgctgctg ggcgcgctgc cgctggcgct gggcaccggc
    19021 gtgggctccg agctgcgcag gccgctgggc atcgccatcg cgggggggct gtgcctcagc
    19081 cagcttttga cgctctacac caccccggtc atctacatga ccctggaccg gatgggccgg
    19141 cgcgtccgcg agtggcgggc gcgccgcttc gcgccccgcg ggcccggcac ggcctgaggc
    19201 ccggaactgg agccgaccat gcgccttcgc ttccatgccg ttgtcctgtc cgccctgggc
    19261 ctcctgcccg cgtgcgcggt gggcccgacc taccaccgcc ccaaggtcgt ggtgcccgcg
    19321 cacttcaagg aggccgcgga gggctggaag cccgccgagc ccaatgacag acatgaccgg
    19381 ggcgcctggt ggaagcgctt cggagacgcg gagctggacg cgctggagac gaaggtcgcg
    19441 agcgccaacc agacggtggc cagctacgag gccgcgtatc gcagcgcgcg cgccctggtg
    19501 gcccaggccc gcgcgtcgct gttccccacc ctgggcgcct ccgtgtcggc gtctcgggcg
    19561 aagggcgccg gccgcaccac caacaccccg gccggcgtca acgcgggcac cagcaccgtg
    19621 ggcaacatcc tggacctgtc gctggatgcg tcctgggagc cggacctctg gggcggcgtg
    19681 cgccggcagc tctccgaagc gaaggcctcc gctcaagccg cgggctccga cctggacaac
    19741 gcgaagctgg ccgcgcaggg gctgctcgcg cagtactact tccagctgcg cgcgctggat
    19801 gccctgcaac tgctgctgaa cgacgccgtc gccggctacc agaagtccct ccagctcacc
    19861 cagaaccgct acgcccaggg cgtggcggcg cggccggacg tgctccaggc ccagacgcag
    19921 ctcgccctgg cgcaggcctc cgcgacggag aatgagattg cccgggccac ctacgagcac
    19981 gccatcgcgg tcctcgtggg ccaacccgcg tccaccttct ccgtgccccg cgtgccgctg
    20041 accgcggcgc cgccgccgct gccgctggag ttcccctcca cgttgctgga gcgccggccg
    20101 gacatcgccg cggcggagcg ccgggccgcc gccgcgaacg agcggatcgg cgtggccatc
    20161 gccgcgtggt ttccctctct cacgctgagc gcgtccggag gcttcgtcag ctccgccctg
    20221 tcgcagtggc tgtcggcccc ccacctggtc tggtcgctgg gaccgcagct ggtggcgagc
    20281 ctcttcgacg gcgggttgcg cgcggcacag acgcggcagg cccgcgcgga gtacgaccag
    20341 gccgtcgcca actaccgggc cacggtgctg gccgcgttcc aggacgtgga ggacaacctc
    20401 gtctcgctgc gcgtgctggc gcaggaggtc gtcat
//
