LOCUS       NZ_CP079946            26715 bp    DNA     circular CON 18-AUG-2024
DEFINITION  Corallococcus sp. EGB chromosome, complete genome.
ACCESSION   NZ_CP079946
VERSION     NZ_CP079946.1
KEYWORDS    RefSeq.
SOURCE      Corallococcus sp. EGB
  ORGANISM  Corallococcus sp. EGB
            Bacteria; Myxococcota; Myxococcia; Myxococcales; Cystobacterineae;
            Myxococcaceae; Corallococcus.
REFERENCE   1  (bases 1 to 9431171)
  AUTHORS   Zhao,Y. and Cui,Z.
  TITLE     Whole-genome sequencing of Corallococcus sp. strain EGB reveals the
            genetic determinants linking taxonomy and predatory behavior
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 9431171)
  AUTHORS   Zhao,Y. and Cui,Z.
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2021) College of Life Science, Nanjing
            Agricultural University, No.1 Weigang Road, Nanjing, Jiangsu 210095,
            China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: FALCON v. MAY-2020
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 113.0x
            Sequencing Technology             :: PacBio RSII
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_019968905.1-RS_2024_08_18
            Annotation Date                   :: 08/18/2024 04:02:55
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,752
            CDSs (total)                      :: 7,680
            Genes (coding)                    :: 7,614
            CDSs (with protein)               :: 7,614
            Genes (RNA)                       :: 72
            rRNAs                             :: 3, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 3, 3 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 66
            CDSs (without protein)            :: 66
            Pseudo Genes (ambiguous residues) :: 0 of 66
            Pseudo Genes (frameshifted)       :: 12 of 66
            Pseudo Genes (incomplete)         :: 62 of 66
            Pseudo Genes (internal stop)      :: 2 of 66
            Pseudo Genes (multiple problems)  :: 10 of 66
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 09:46:24
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 5460937
            Orig. end                         :: 5487652
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP079946.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from College of Life Science,
            Nanjing Agricultural University, China.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..26715
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="azole-containing-RiPP"
                     /region_number="23"
                     /rules="((YcaO or TIGR03604) and (((thio_amide and (PF06968
                     or PF04055 or PF07366)) or Lant_dehydr_C or Lant_dehydr_N
                     or (PF06968 or PF04055 or PF07366)) or (goadsporin_like or
                     PF00881 or TIGR03605)) or TIGR03882 or TIGR03603 or
                     thiostrepton or TIGR03602)"
                     /tool="antismash"
     cand_cluster    1..26715
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="((YcaO or TIGR03604) and (((thio_amide
                     and (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /kind="single"
                     /product="azole-containing-RiPP"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..26715
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:16715](+)"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..16715
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="1"
     misc_feature    1803..1818
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.27"
                     /tool="antismash"
     gene            complement(1863..2294)
                     /locus_tag="KYK13_RS22560"
     CDS             complement(1863..2294)
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014397419.1"
                     /locus_tag="KYK13_RS22560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="response regulator"
                     /protein_id="WP_223632971.1"
                     /transl_table=11
                     /translation="MTTATAGDRTLHILLVEDDEVDVMNVRRAFQKNHIANPLYVATNG
                     LEGLEMLRNGAVPEGRRLVLLDLNLPKMNGIEFLRVLRADPELRTISVVVLTTSADERD
                     KIDAYNLNVAGYLLKPVTFINFVEVMATLNKYWTLVEMP"
     misc_feature    complement(2358..2369)
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 18.46"
                     /tool="antismash"
     gene            2524..3294
                     /locus_tag="KYK13_RS22565"
     CDS             2524..3294
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF014567.4"
                     /locus_tag="KYK13_RS22565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ATP-binding protein"
                     /protein_id="WP_223632974.1"
                     /transl_table=11
                     /translation="MRRSPPKDDSQKTQQELIEELQGLRRALRQNSADLEQFSYVASHD
                     LRAPLRGISNLSQWLEEDLGPQLPQATRRQMELLRGRVQRMEAMLDGLLDYSRAGRVRD
                     KPEPVRVDRLIHETLERLSPRPSARLEVGSGMPELVTERSALQQVFHHLLSNALKHAGR
                     EDVRIRVEVEATPAAHRFSIADDGQGISPRYHEKIWNPFQTLVSRDKVEGAGMGLCVVR
                     KLVEARGGQAWVESAEGAGATFHFTWPVSEERLT"
     gene            3291..5834
                     /locus_tag="KYK13_RS22570"
     CDS             3291..5834
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF024583.4"
                     /locus_tag="KYK13_RS22570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="response regulator"
                     /protein_id="WP_223632976.1"
                     /transl_table=11
                     /translation="MSLPPASTSSVEVAPVAEHLRLLLVDDDEVDRLRVQRLLGATGLS
                     VDVVEATSGSEALEHLKARAFDVILLDFFLPGEDGFWVLRELGSRGSHAPIVVLTGQGS
                     EQTAVALMKAGASDYIAKGQLSAERLEQSLRQAMRLHLAEQRHRALAEALPQIVWTSGP
                     DGRPDYFNRRWYDYTGLPPAPSLEERGSTAPLLPRDVIHADDVAGCLGKWNETRHAGAA
                     FECEGRIRRHADGAWRWHLIQAVPLRNAHGRILQWLGTCTDIDDQKRAAETLSFLAEAS
                     TMLTASLEMSVTLERLAALILPRLGDWCAVYLQEDDGPVRQVMAAHADPTRVPLLREQH
                     RAFPPSAAARHGVARVLRTGAPELVPELTDAVLQEALGPAGDDERIRPGSWIIVPLWAQ
                     RRVFGALMVCAARAGLRYGARDLELVQELARRAEIAIDNARLFEMAKAEHLVAEQANRA
                     KDEFLAAVSHELRTPLMAMLGWTRMLRTGQLGPEKTARALAAVERNTQVQTQLIEDLLD
                     VSRIITGKMRLEIRPVDPAAFIEAALDSVRHAAEAKGVTLSAELLPGSGSIHGDADRLQ
                     QMVWNLLSNAIKFTPRGGQVTVRLRWVEGHVLIEVQDTGQGIPRAHLGQIFERFWQVDG
                     SSTRKHGGLGLGLAIVRHLTELHGGTIEALSEGEGHGALFRLTLPLSVAASSRGSPPVA
                     QSQARQEAPSLAQEVLKGLQVLVVDDEADALELLSVVLESRGAQVHTASSAREALEKHQ
                     LHRPHVILSDIGMPGEDGYSFIRRLRALPLEQGGQTPAVALTAFARMEDRTRALLAGFQ
                     MHVPKPIEPAELIIVLASLTGRYPRVVDSAFQAVR"
     gene            complement(5885..8077)
                     /gene="katG"
                     /locus_tag="KYK13_RS22575"
     CDS             complement(5885..8077)
                     /EC_number="1.11.1.21"
                     /GO_function="GO:0004096 - catalase activity [Evidence
                     IEA]"
                     /GO_function="GO:0004601 - peroxidase activity [Evidence
                     IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /GO_process="GO:0006979 - response to oxidative stress
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="katG"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020044279.1"
                     /locus_tag="KYK13_RS22575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="catalase/peroxidase HPI"
                     /protein_id="WP_255653962.1"
                     /transl_table=11
                     /translation="MNDEAKCPVAHGPRRARTNAQWWPEQLNLAMLHQHSSLSDPMVED
                     FNYAAEFQTLDLNAVVKDLHALMTDSQDWWPADYGHYGPFFIRMAWHAAGTYRIFDGRG
                     GARSGEQRFAPLNSWPDNGNLDKARRLLWPIKQKYGRKLSWADLMILSGNVALESMGLK
                     TFGFGGGREDIWEPHTTDWGPESTWLGDERYSGERELAHPLAAVQMGLIYVNPEGPNGK
                     PDPVGSARDIRETFARMAMNDEETVALVAGGHTFGKCHGAGPVHHVGAEPEGANIEELG
                     LGWKSTYESGVGEHATTSGLEGAWTPTPTKWDMTYFEVLFGYEWELTRSPAGAHQWKPV
                     GNTGAGTVPDAHVPGKRHAPMMTTADLALRFDLIYERISRDYMANPAKFADAFARAWFK
                     LTHRDMGPRSRYLGPLVPKEELLWQDPIPAVDHPLIDATDIDALKAELLGSGLSIQQLI
                     KTAWASASTFRGSDMRGGANGARIRLAPQKDWEANEPSELAKVLSKLEAIRQKFNGAQR
                     GGKRVSLADLIVLGGSAGIEAAARAAGHKITVPFTPGRMDASQEQTDVESFLVLEPAAD
                     GFRNYVRAGAEATTAAALIDRASLLTLTAPEMTALVGGLRVLDVNHGHTPHGVFTKRPG
                     QLTPDFFVNLLDMRTAWKRSEKTSNVFEGRDRATGDLRWTATVADLVFGSNSQLRALAE
                     VYAASDGTAHFVQDFVDAWTKVMNADRFDLPGRKTI"
     gene            complement(8221..9906)
                     /locus_tag="KYK13_RS22580"
     CDS             complement(8221..9906)
                     /GO_function="GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012311.4"
                     /locus_tag="KYK13_RS22580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="protease pro-enzyme activation domain-containing
                     protein"
                     /protein_id="WP_223632979.1"
                     /transl_table=11
                     /translation="MAPRIPLAQSARVSPASLHLPLRSRAATGLVEVTLVLRHGAPLPT
                     VEELCANPPRRPLTHEEFEAKYGTPPKHLAAVRRFAKSHRLTITSERRDRGCVTLQGAA
                     AAMCKAFGVDLRRFTQGRTSYLSHTKPVTLPRALRGVVEWVLGLDTRPLVTHNAASLPI
                     PREAAKQVGLRSYTAPQVASLYRYPQNQGEGQCVGVIELAGGYRPSDLEASLKSAGVKR
                     TAPVVNVGPNKVGILHTASDAEVTMDVELVAAVCPAARVVVYNAGSKDYSLRDYHRVLA
                     EALSDRENRPSVLTTSWSFYEGSLIQQGEEGVFERLFVEAALLGITVCAASGDLGSQVP
                     VNAVSPTGAITLAATSYPAASALVLGCGGTTLEAVGDVLHHERVWNRLGEAMSMGLLGR
                     MSTAAGASSGGVSTMNALPLYQQGMGVPDLVRSSWKNGAFDVSRSTGRGVPDVAANADL
                     HTGYQIVFKGQQGVAAGTSAAAPMWAALIVRLNEALGERVGFLNPRLYTLVTEGEAVVR
                     RITQGGNGAYFASEETLWNACTGLGTPDGEALLAGLRKLLRRKH"
     misc_feature    9976..9994
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: weak, score: 22.57"
                     /tool="antismash"
     aSDomain        10001..10294
                     /aSDomain="Goadsporin_CD_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing CD fusion protein in a
                     goadsporin cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_KYK13_RS22585_Goadsporin_CD_RRE.1"
                     /evalue="8.50E-20"
                     /identifier="RREFam013.1"
                     /label="KYK13_RS22585"
                     /locus_tag="KYK13_RS22585"
                     /protein_end="98"
                     /protein_start="0"
                     /score="61.7"
                     /tool="antismash"
                     /translation="MDRVLRIKPHLRAEVLDSRRVFLVGERAQFLLEGELHASIVPLLD
                     GERTVASVIAALAGRASAPEVLYALSLLEERGHVEEAHDVFDASVAGFWESLG"
     gene            10001..12187
                     /locus_tag="KYK13_RS22585"
     CDS             10001..12187
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: TIGR03604"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: YcaO"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Goadsporin_CD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Cyanobactin_D_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NHLP_CD_RRE"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002613718.1"
                     /locus_tag="KYK13_RS22585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="TOMM precursor leader peptide-binding protein"
                     /protein_id="WP_223632981.1"
                     /sec_met_domain="Goadsporin_CD_RRE (E-value: 2.3e-17,
                     bitscore: 61.7, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="Cyanobactin_D_RRE (E-value: 3.6e-23,
                     bitscore: 80.2, seeds: 10, tool: rule-based-clusters)"
                     /sec_met_domain="NHLP_CD_RRE (E-value: 1.1e-19, bitscore:
                     69.1, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="YcaO (E-value: 4.5e-87, bitscore: 291.7,
                     seeds: 127, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR03604 (E-value: 1.5e-74, bitscore:
                     249.9, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDRVLRIKPHLRAEVLDSRRVFLVGERAQFLLEGELHASIVPLLD
                     GERTVASVIAALAGRASAPEVLYALSLLEERGHVEEAHDVFDASVAGFWESLGVGASTA
                     AGRLLDMSVAVRAVAGEDAERLSEALRDAGLDVRDDAERHVLLVDDYLSQEALALARES
                     RGAGAAFLPLKVSGTTCHAGPVVGPERACWTCLTARLLDNRPIEKYLARKGIPPSAIRP
                     PRTGLPTTAQAGLSLAATLVARWVVDGPQAAGQTRLWTLDFATWKLQSHAVTRRPQCPD
                     CGDPHWMDARAKAPLELTSRPKRFTDDGGHRILTPEETWERHRHLISPVTGVVSDLRAV
                     PGDAPLGHIQSAVFRVCPWTDAPASDDFHRVASGKGRTEAQARAGALCEALERYSAVFQ
                     GDEPRVHATASHLGVQAVHPDALQHFSAAQFQARSEGAGRRDMRTAVPRPYADQPMDWS
                     PAWSLTHGVSRYVPTAFAYLFAPTPADGPFCFFNSNGNAAGNCVEEAILQGFLELVERD
                     AVALWWYNRLRRPRVELRSFDEPWFTSVEAHYRSLGLRLSVLDLTHDLGIPVFAALAWS
                     PERGRAWAGCGCHFDAKLAVQRALTEVAQCYDPKDLTPSPWDSRAHDDTHWLFPDDTVP
                     ARVRADFPRVWHDDLRDDVHECVARAERVGLETLVLEQSRPDVGVSAVKVIVPGLRHFW
                     PRLGPGRLYDVPVRMGWLKAPKTEAQLNPVPFYF"
     aSDomain        10004..10237
                     /aSDomain="Cyanobactin_D_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing D protein in a cyanobactin
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_KYK13_RS22585_Cyanobactin_D_RRE.1"
                     /evalue="1.30E-25"
                     /identifier="RREFam007.1"
                     /label="KYK13_RS22585"
                     /locus_tag="KYK13_RS22585"
                     /protein_end="79"
                     /protein_start="1"
                     /score="80.2"
                     /tool="antismash"
                     /translation="DRVLRIKPHLRAEVLDSRRVFLVGERAQFLLEGELHASIVPLLDG
                     ERTVASVIAALAGRASAPEVLYALSLLEERGHV"
     aSDomain        10004..10285
                     /aSDomain="NHLP_CD_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing CD fusion protein in a
                     NHLP/Nif11 LAP cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_KYK13_RS22585_NHLP_CD_RRE.1"
                     /evalue="3.90E-22"
                     /identifier="RREFam015.1"
                     /label="KYK13_RS22585"
                     /locus_tag="KYK13_RS22585"
                     /protein_end="95"
                     /protein_start="1"
                     /score="69.1"
                     /tool="antismash"
                     /translation="DRVLRIKPHLRAEVLDSRRVFLVGERAQFLLEGELHASIVPLLDG
                     ERTVASVIAALAGRASAPEVLYALSLLEERGHVEEAHDVFDASVAGFWE"
     gene            12191..14143
                     /locus_tag="KYK13_RS22590"
     CDS             12191..14143
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: PF04055"
                     /gene_functions="other (smcogs) SMCOG1277: Radical SAM
                     domain protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF015983.4"
                     /locus_tag="KYK13_RS22590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="radical SAM protein"
                     /protein_id="WP_223632983.1"
                     /sec_met_domain="PF04055 (E-value: 1.5e-11, bitscore: 43.7,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAPLPEPKPRVLLIQCGPDRRHVDRETEDFDPERGLVKRATMTPL
                     ACATLAALTPDRFTVDIWDEELHGQLRADTELPDYDIVGVSVMYSALTYQARFLGGHFR
                     DRGATVVAGGPAVSAAPEDYRGFFDALFVNEAERTWPRFLADWLSGEYAPEYRQLDKPS
                     LSESPLPRWDAVAVDLPRYAWGSVQTTRGCPFDCSFCDVIYLYGRKQRHKPVERVLDEV
                     RAHAALGAEGVFFADDEFIGDAAYAKQVLAGLVPLNRALPRPLRFFTQVTMNLSRDAAL
                     LEGMADANFYTVVLGIESFDPAALKEAQKHQNVRADLVGDLLRIQAHGIGPRGSFIVGF
                     DHDTPAVFDSLHANIQRTHLPWVVVAPLQAPRGTKLWTRLRAEGRLATPRKAHAKDRGA
                     IVLNVMPLGMTRPQLLEGFRDLVERLSSWDAACERIRGFISGIQRPPQVREVPWPEAVT
                     DRFLREATAAWALTPPERQALGDTLAQVRRTAPAMVPRAVFFLARNQNERRRHERLFTD
                     FDAVLAAERQGDLVPDSQPVYVPPGFAAAMRDVFPDLFVRLSRDLPDRRDVPEASRDVL
                     VDFVARWGEGFQVLQPQHHEFLRELCDREVAARGGRPGTLEASEEQALRTQARRTGLLE
                     ALLKDVRDELASWGP"
     gene            14147..15304
                     /locus_tag="KYK13_RS22595"
     CDS             14147..15304
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014397426.1"
                     /locus_tag="KYK13_RS22595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="amidohydrolase family protein"
                     /protein_id="WP_223632998.1"
                     /transl_table=11
                     /translation="MRDGLRIFDADRHVLEPLSLWAEQLEPRLRRHAPRPGRLPDETLE
                     ERLERLGPQGLLPVLPLPEVDGKPLWNHMPEKAWVEFSARSYAQLGRNELLQRPDVYLA
                     QMDRDGVDMAALFPTHALLLEGFSPLKPHVATAFASVYNTWLHGFCAHAPERLRGVGLI
                     SRHEPEAMVAEVRRVAGFGWRAVMVRPNPIGGRLLSDAAYEPFWSECERRSLAVVLHGS
                     GHVYVPSAGADRFDTRFANHVCAHPMELMMGLLALLQGGVLERHPALRIGAMEAGCGWL
                     PYWAWRLDEEYRAVGAEVSATIRQLPSSYLRQHCFVSVEPDEPYLADVVRHLPEDRLVF
                     GSDFPHLDHGEDVLGSLLSLRDAMTESRLRKVLWENPTRFYGVEP"
     gene            15315..16715
                     /locus_tag="KYK13_RS22600"
     CDS             15315..16715
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: PF00881"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF013077.4"
                     /locus_tag="KYK13_RS22600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SagB family peptide dehydrogenase"
                     /protein_id="WP_223633001.1"
                     /sec_met_domain="PF00881 (E-value: 5.8e-07, bitscore: 28.5,
                     seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRLSLAEGVALRCPDAEDARVEGPGRSLRLGPLAPGVRAVFESLA
                     DGGIHESEVPAAAGRDTTLAWYWLDLAGDGGLLSWTVEERGNLLLTLTPASASFLRHRA
                     TFDAAQPLQLSRFAHTRMAEGRAVLDCPTVHATAALHDRRVVSLLFDMARPTLLARLNQ
                     FNTGIESFTLRELVRLLAETGILVPNGLDVPASEETQTALKQWEPHDLLFHLRSRGWGH
                     QTRAGATYRFRGELPNPPALKPSIIQEAVELYRPDMEALRAEDRSFTEVLEARRSLRGR
                     GASPLTLRQLGELLYRAARVRDVRTTQDGEITDRPYPGAGAVYALELYPLVGECQGLAP
                     GAYHYDPLGHRLEKLSGPTPEFHALMDEARAPAEPFERPEVLMVVAARVPRLAWKYETL
                     AYSLVLQDTGALVQTLYLVSTALGLRPYALGRSDPDFFQRVAGVDGFGEASVGAFAVSG
                     GDAPARDR"
     gene            complement(16746..17159)
                     /locus_tag="KYK13_RS22605"
     CDS             complement(16746..17159)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR03795"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:TIGR03795.1"
                     /locus_tag="KYK13_RS22605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="BMA_0021/BMA_0022 family TOMM bacteriocin"
                     /protein_id="WP_223633005.1"
                     /sec_met_domain="TIGR03795 (E-value: 3e-21, bitscore: 74.5,
                     seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKKKPESKAAPARARPVARKPTRSTGGQASVNDWQAVWMRAVAL
                     AWKEPEFEAALQKNPREALKKRFDFDLPASIHLKVVPTTEKDAAADGTWKVNSAEVELH
                     LPKKPADVADHAVALSSLTDTYGRSHCCGSPCC"
     gene            complement(17161..21252)
                     /locus_tag="KYK13_RS22610"
     CDS             complement(17161..21252)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014397429.1"
                     /locus_tag="KYK13_RS22610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="TOMM system kinase/cyclase fusion protein"
                     /protein_id="WP_223633008.1"
                     /sec_met_domain="Pkinase (E-value: 2.8e-49, bitscore:
                     166.6, seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDPQLLEAFQGRYELLSELGEGGFGRVYKARQVTTGQNVAVKLLR
                     LTDGATPESVERRSARFEREMKLCAQMHHPNIVRLIDSGRAQGGAVYSIFEFVPGKNLA
                     QVLAEEGALDPVEARHLMLQLLDALACAHAQNVVHRDLKPANIMVVPTGARRNALVLDF
                     GIGSVTDEIAREEGQPRITSTNESLGTPSYAAPEQLRGQAPTPRSDLYAWGLVFLECLT
                     GRRVYEAATVAEVIFQQLSTEPVPIPPVIAAHPLGKLLQRVTAKDPSQRTVAAEVLLRQ
                     LEAVDVSNLPRRQAPVRIQPAAPNAETATVELSSRTPNALSTRSRRWAEGERRQLTVVC
                     CTLSATQTTPGPVDIEELDHVLGAQQEVCIEIARRHNGHIASALGDIVLFYFGYPAARE
                     DDARRAAQAALDMVAEVKRRGRAIEAERGTRVEIRVGLHTGLVVSREQRDPTLSGLGFV
                     VGTTPKLAFRLSTSAPPGVILLTGDTQQLVRKHFPLESVPAAPSELLPPGLETFALQGA
                     DATWSGTDDTLALVGRSRELDLVLSRWEQVRSGQGQAVLLSGEPGIGKSRLMRELGDRL
                     GAEPHTWLEARCTADGSGQAYAPVVELLSRMLDPNRDLSPEARLTGLEALLSGYSFELP
                     ETVPLFAPLLSLPLPPERWAPLDVSPLKHRELTRDALLALLAAMAERQPVVLSLEDLHW
                     ADPSTLELLKALVEEVSSSRLLSVFSARPEFEPPWAASSVTQVQLGTLGRSEVERLATS
                     AVGGPLSPEAVEEIVTRTDGIPLFVEELVRTLRESGALVEREGRFALEAGKAGPAVPGT
                     LRDLLVARLDRLGRAKETAQVASVLGRELTHELLRHVSPLTPEALDADLERLVASGLLH
                     RKRRPKGPVYLFKHALVRDAAYDSMLKRYRQQVHAKTAEALEAHFPEQAESRPDLLAHH
                     LSAANLKRKAIVYAQKAAFAALVRSAYLEAILFARLGLSWLDAIEDPVERAQQELGLNG
                     VLAPALMSSQGWRSQDLRTVAERSLELLFTVGESPYAAPTLWVLSIFYHLGGDQRRVRG
                     LLDRLVALAQHNGDAGQEAVALTILSNIELLEGRLGEAKAKADRCLSLFDPVAHRMHHI
                     LYGQDTRVGGESVLCRGLWLLGFPDQAKAHGEAAVAWGRELKHGTSVGLSFIYLLLMAQ
                     EHGDRTEALNLVAQHSELSHRYGLLEQSAYVGILRGWAAKDLEAMRRGVAMREAFGTEM
                     DQPAYYGMLAELELELGHLEAALATVERGLQRAQALGEAYHESKLLRVKGQVLLQRDGN
                     TALSAESCFRQAADVAHAQGARMRELQAVTALARLLQASGRQEEARQRLQTVYSTFSEG
                     WGTPPISEARALLGALGGDC"
     gene            complement(21261..23039)
                     /locus_tag="KYK13_RS22615"
     CDS             complement(21261..23039)
                     /GO_function="GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014397430.1"
                     /locus_tag="KYK13_RS22615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="FHA domain-containing protein"
                     /protein_id="WP_223633028.1"
                     /transl_table=11
                     /translation="MLVYNPGQPDELSYPLGDAPITIGRADDQGICIPHRSLSRQHARI
                     ESSDGRFFVTDLQSKNGTFVNGVQIRRKELRPGDTLTLGELVFLLTHEPPPVAPSGPPG
                     AAAHEPRPQLTRALTRVPLKTLVQAVSGQEPPPVEAASAATRSRERMRILQEVAKLLSV
                     TDDLEALPGKVLDLAFQILRVDRGVILLMDEATGRLEPRVTKTAEGAAVRGPIYSQNIV
                     DFVLRRSVAALFSDAVNDPRLGAAESVIFSSIRASMCVPLKPRDEVLGVLYVDNVSTPK
                     SFSEDDLDFLVAFAGQAALALENARLYRRIEQETVQRMQLIMDAKLASLAALVGGMAHE
                     LRNPLNFISNFAGLSVGLTEDLAGVLEPQRERLTPDSVRDVDEALVCLRTNVQKIHEHG
                     RRADAVIQGMLQHARRAPGPREPVDLNALVAESVALGLGGMRGEALTVRLEAEYDPAVG
                     PLELSRADVGRVIINVVDNALYAMRQKRQAQGAAYAPVLKVRTLARPEQVEVRLRDNGP
                     GIPSESARRIFDPFFTTKPPGQGTGLGLSLSHDIIVQGHQGTFRMETVPGEFTEFVITL
                     PRRGGRSSMERGSGAR"
     misc_feature    complement(23065..23083)
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: weak, score: 24.29"
                     /tool="antismash"
     gene            complement(23113..23673)
                     /gene="cysC"
                     /locus_tag="KYK13_RS22620"
     CDS             complement(23113..23673)
                     /EC_number="2.7.1.25"
                     /GO_function="GO:0004020 - adenylylsulfate kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0000103 - sulfate assimilation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="cysC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014397431.1"
                     /locus_tag="KYK13_RS22620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="adenylyl-sulfate kinase"
                     /protein_id="WP_223633032.1"
                     /transl_table=11
                     /translation="MQQRPGFILWFTGMSGAGKSTLSAAVARQLSPVQRVELLDGDEVR
                     TYLSRGLGFSREDREENVRRIGYVARVLAKHEVGVITAAISPYKSSRDEVRALATQAGI
                     PFLECYVQASLDALIARDVKGLYKKALAGEIPHFTGVSDPYEPPESPEITVRSDAETVE
                     AGLERILDTLRDRGLLASAASAA"
     gene            complement(23683..24948)
                     /locus_tag="KYK13_RS22625"
     CDS             complement(23683..24948)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1190: GTP-binding protein LepA"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014397432.1"
                     /locus_tag="KYK13_RS22625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="sulfate adenylyltransferase subunit 1"
                     /protein_id="WP_223633035.1"
                     /transl_table=11
                     /translation="MELLRFATAGSVDDGKSTLIGRLLYDTKSILEDQLAAVERTSQAR
                     GDEYVNLALLLDGLKAEREQGITIDVAYRYFSTQKRKFIIADTPGHLQYTRNMVTGAST
                     ADLALILVDARKGVLEQTRRHAFIASLLRVPHLVLCVNKMDLVDFDPGVFDRIRDEFRQ
                     FSMKLDVTDLSFIPISALGGDNVVTRSEKMPWYQGPTLLHHLENVHIASDRDLIHLRFP
                     VQGVIRPASAKKFHDYRAYSGQLLGGVMRVGDEVMVMPSGFTTRIKALELAGKPLKEAF
                     PPMSVNVSLEEELDISRGDMLCRPGNPPTASQDIDAMVCWLSESSQLSSGSRLAIKHTT
                     RMARAMVKQLHYRLDVNTLHRDEQSPGLKLNEVGRVTLRTTVPLFFDEYRRNRSTGSFI
                     LIDESTNATVGAGMINGPAVDR"
     gene            complement(24948..25853)
                     /gene="cysD"
                     /locus_tag="KYK13_RS22630"
     CDS             complement(24948..25853)
                     /EC_number="2.7.7.4"
                     /GO_function="GO:0004781 - sulfate adenylyltransferase
                     (ATP) activity [Evidence IEA]"
                     /GO_process="GO:0000103 - sulfate assimilation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="cysD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014397433.1"
                     /locus_tag="KYK13_RS22630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="sulfate adenylyltransferase subunit CysD"
                     /protein_id="WP_223633037.1"
                     /transl_table=11
                     /translation="MSYELSHLEALEAESIFIIREVAAELDRPVLLFSGGKDSAVMLHL
                     AVKAFWPAPLPFPLMHVDTGHNFPEVIQYRDERVAELGARLIVASVQEAIDAGKVTEEK
                     GPRASRNRLQTQPLLEAIEKNGFNAVFGGARRDEEKARAKERVYSFRDEFGQWDPKNQR
                     PELWALYNGRHRRGEHLRVFPLSNWTELDIWQYIARENVALPSIYYTHRREVFRRDGML
                     MAWSPFMTMMPGETVTTETVRFRTVGDMTCTACVPSTASTVEQVIAEVTASRVTERGAS
                     RADDKFSETAMEDRKREGYF"
     misc_feature    26028..26041
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 19.25"
                     /tool="antismash"
ORIGIN
        1 tgaggtgggt gcccagctcc tccttgagcc actccgccag gttggcgatg ccccgcagcg
       61 gcgccttgag gtcgtgggag gccacgtagg cgaattgatc cagctcgcgg ttggactgct
      121 ccagcgcctg ggtgagccgc accagctccc gcatccgctc ctccgcctgc tggcgggccc
      181 gcaccatgtc ggtgacctcc accgcgtggg tcatcacgcc gaaggtggcc ccgtcctcgt
      241 cggtgagcgg ctggtagacg aagttgaagt acgtgtcgtc cacccggccg aagcgctcga
      301 cccgcacggg cacctcgttc ccgacgacgg cctgcttcgt ggcgtacacc tgatcataga
      361 gttcgaagag cccctgcccc gccaggtccg ggaaggcgtc cgggatcgtc ttccccacca
      421 ggggccggtt gcccgtcacc tgcgcatagc ccgggttgac gacctggatg acgtgctggg
      481 gcccgcgggc caccatgatg gcggcgggcg cctgcatgaa gacctgcgtc agccggttgc
      541 gctccagctc cagctgctgc tccaggcggt gctgctgggt gatgtcccgc agggtgagca
      601 ccacgcccag atggacgcgg gcgtcggtgt acaccgggac ggcgctgccc tggacgcgca
      661 gcttgtggcc atcaggcgtg cggatgatcc acacctcgtt gaggacgcgc tccccccgcc
      721 ccgcccgcgc cgagggcagc tcgtcggcgg agagcggcgt gccgtccacc cgctcctgcc
      781 ggaagccctg ggtgtcgaag gtctccccct cgcccagccc cgggtagagg gtccgggcca
      841 tctcgttgag gaagctgacc cggcccgccg ggtcgaacgt gagcaccgcg tccgcgatgt
      901 ggcccagcat cgcggcgcgc tcggcggcga gcgcctcgat gctcctgcgg gccagcacct
      961 gctccgtggt ctccaccgcg tgcgccatga tgccgaacac gctgccgctc gcgtccttga
     1021 ggggctggta gacgaagtcc acgtagacgt cctccacgac gccggtgccc ttgcggtcca
     1081 gccggaccag cgcgtcgtgc gcgatgtacg gctggccgct cgtcctcacg gagtcgagca
     1141 gctcccggaa gccctgatcc gcgatctcgg gcagggcctc cgtcaccggc ttgcccagca
     1201 ggtcccggtt gcccgtcagc tgctggtaca gcgggttgga cacgctgaag cggtggtccg
     1261 gcccctccag cacggcgatg atggccggag cctgcatgaa gacctcgtac aggcgctcgc
     1321 gctccgcccg cgcctccgcc agcgcgcggt cgcgctcctt gcgcgcgcgg acctcccggg
     1381 tcacgtcgaa gatggagacg aagacgccgc ccacggcgcc cgtctcgtcg cggaccgggc
     1441 tgtagcagag cgtgaggtag aactcctccg ggtggccgtg cggctcgagc gggtacatcc
     1501 gctcctcgaa cgtgaccgtc tccccgttga agatgcgcgg gtagatggcc tcgttgatgt
     1561 gccacacctc cggccagcac tccttgttgc cctgccccag gcccccaggg tgcttgcggc
     1621 ccatgagcag ccggtaccca tcgttgtaga actggtagag ctccggtccc cacaggacga
     1681 tgagcgggaa ctgggagccc agcaccatgc tcaccgcggt cttcaggctc tggggccagg
     1741 cgtccacggg ccccagcggg tgcgtgctcc agtccttcgc ccggcacagc gcgcccagct
     1801 ctccgccgtt ggcgaagacc cgctcggccg cgtcggctcc cggcttccac tgcacggtca
     1861 tgtcagggca tctccacgag ggtccagtac ttgttgagcg tggccatgac ctccacgaag
     1921 ttgatgaagg tgacgggctt gagcaggtag ccggcgacgt tcaggttgta cgcgtcgatc
     1981 ttgtcgcgct cgtccgcgga cgtggtgagc accaccacgg agatggtccg cagctccgga
     2041 tccgcgcgca gcacgcgcag gaactcgatg ccgttcatct tcgggaggtt caagtccagc
     2101 agcaccagcc ggcgcccctc gggcaccgcg ccgttgcgca gcatctccag gccctccagg
     2161 ccgttggtgg ccacgtagag cgggttggca atgtggttct tctggaaggc gcggcggacg
     2221 ttcatcacgt ccacttcgtc gtcttccacc agcaggatgt gcagcgtccg gtcgccggcg
     2281 gtagcggtgg tcatctcaag cctttcgagc ctgcgcggca tccagaccca agaggagccc
     2341 gagcacgctg gcatctagcg ttcgctttcg ggcggatatc aggcaccttg gggcgactgt
     2401 ccgctttgtg acgcgattcc ccgcacgccc gcccgggagg ccgcctgggg agtgtcgtct
     2461 gctcatcact ccgcgcccgc gggttgaggg cccgcgcgcg gggacggtat ggcgaaaggc
     2521 cctgtgcgcc gttcccctcc caaggatgac tcccagaaga cccagcaaga gctcatcgag
     2581 gagctccagg gcctgcgcag ggccctgcgg cagaacagcg ccgacctgga gcagttcagc
     2641 tacgtggcca gtcacgacct ccgggctccg ctgcggggca tctccaacct gtcccagtgg
     2701 ctggaggagg acctggggcc acagctgccc caggcgacgc gcaggcagat ggagctcttg
     2761 cgagggcgcg tgcagcggat ggaggcgatg ctggatggcc tcctggacta cagccgggcg
     2821 ggccgcgtcc gcgacaagcc ggagccggtg cgggtggacc ggctgatcca cgagacgctg
     2881 gagcggctgt ccccgcgtcc gtccgctcgg ctggaggtcg gctccgggat gccggagctc
     2941 gtcacggagc gctccgcgtt gcagcaggtc ttccaccacc tgctctcgaa cgcgctgaag
     3001 cacgcgggcc gcgaggacgt gcggatccgc gtggaggtgg aggccacgcc cgctgcccat
     3061 cgcttctcca tcgcggatga cggccagggg atctcccccc gctaccacga gaagatctgg
     3121 aacccgttcc agacgctcgt ctcgcgcgac aaggtggagg gcgccggcat gggcctgtgt
     3181 gtcgtcagga agctcgtgga ggctcgcggc ggccaggcct gggtcgagtc ggccgaaggc
     3241 gcaggcgcca cgttccactt cacctggccc gtgtcagagg aacgcctcac gtgagtctcc
     3301 cccctgcctc cacctcctcc gtggaagtcg cccccgtggc ggagcacctc cggctgctgc
     3361 tcgtggatga cgacgaggtc gaccggctcc gggtccagcg gctcctgggc gcgacgggac
     3421 tctcggtgga cgtggtggag gccacgagcg ggagcgaggc gctggagcac ctgaaggcgc
     3481 gcgccttcga cgtcatcctc ctggacttct tcctgccggg ggaggacggg ttctgggtgc
     3541 tgcgcgagct gggcagccgg ggctcgcacg cccccatcgt cgtcctcacc ggacagggca
     3601 gtgagcagac ggccgtcgcg ctgatgaagg cgggcgcgtc cgactacatc gccaagggtc
     3661 agctgtccgc ggagcggctg gagcagagcc tgcgccaggc gatgcggctg cacctggcgg
     3721 agcagcggca ccgggcgctc gcggaggccc tgccgcagat tgtctggacg tcgggcccgg
     3781 acgggcgccc cgactacttc aaccggcgct ggtacgacta caccggcctg ccccccgcgc
     3841 cttcactgga ggagcgcggg agcaccgccc ccctgctccc gcgggacgtc atccacgccg
     3901 acgacgtggc gggctgtctg ggcaagtgga acgagacccg ccatgcgggg gcggcgttcg
     3961 agtgcgaggg ccgcatccgg cgtcacgcgg acggcgcgtg gcgctggcac ctcatccagg
     4021 ccgtgccgct gcgcaacgcg catggccgca tcctccagtg gctgggcacc tgcaccgaca
     4081 tcgatgatca gaagcgcgcc gcggagacgc tgagcttcct ggcggaggcg agcaccatgc
     4141 tcaccgcctc gctggagatg tccgtcacgc tcgagcggct cgccgcgctg atcctcccgc
     4201 ggctgggcga ctggtgcgcc gtctacctcc aggaggacga cggccccgtg cgccaggtga
     4261 tggcggccca cgccgacccc acccgggtgc ccctgctgcg agaacagcac cgcgcctttc
     4321 ctccgtccgc cgccgcccgc cacggcgtcg cgcgggtgct gcgcacgggc gcgccggagc
     4381 tggtgcccga gctcaccgac gccgtcctcc aggaggcgct gggcccggcg ggggacgacg
     4441 agcggatccg cccggggtcg tggatcatcg tcccgctgtg ggcgcagcgc cgcgtcttcg
     4501 gcgcgctgat ggtctgcgcc gcccgtgccg gcctgcgcta cggcgcgcgg gacctggagc
     4561 tcgtgcagga gctggcgcgg cgggcggaga tcgccatcga caacgcgcgg ctgttcgaaa
     4621 tggccaaggc ggaacacctg gtcgccgagc aggccaaccg cgccaaggac gagttcctgg
     4681 ccgcggtctc ccacgagctg cgcaccccgc tgatggcgat gctggggtgg acgcggatgc
     4741 tgcgcacggg ccagctgggg ccggagaaga ccgcccgcgc cctggcggcg gtggagcgca
     4801 acacgcaggt gcagacgcag ctcatcgagg acctgctcga cgtgtcgcgg atcatcaccg
     4861 gcaagatgcg gctggagatc cgcccggtgg accccgccgc cttcatcgag gcggcgctgg
     4921 attcggtgcg gcacgcggcc gaggcgaagg gcgtcacgct ctccgccgag ctgctcccag
     4981 gctccggctc catccatggc gacgcggacc ggctgcagca gatggtctgg aacctgctct
     5041 ccaacgccat caagttcacg ccccggggcg gccaggtcac cgtgcgcctg cggtgggtgg
     5101 agggccacgt cctcatcgag gtccaggaca cgggccaggg catcccccgg gcgcacctgg
     5161 ggcagatctt cgagcgcttc tggcaggtcg acggcagctc tacccggaag catggcggcc
     5221 tgggactggg gctggccatc gtgcggcacc tcacggagct gcacgggggc accatcgagg
     5281 cgctgagcga gggcgaggga catggcgccc tcttccggtt gacgctgccg ctgtcggtcg
     5341 cggcctcgtc gcggggaagc cctcccgtcg cccagtccca ggcgcggcag gaggcgccat
     5401 cgctcgcgca ggaggtgctg aaggggctgc aggtgctggt ggtggacgac gaggccgacg
     5461 cgctcgagct gctctccgtc gtgctggaga gccgcggcgc ccaggtccac acggcctcca
     5521 gcgcccgcga agccctggag aagcaccagc tccaccgccc gcacgtcatc ctctccgaca
     5581 tcggcatgcc tggagaggac ggctactcct tcatccgcag gctgcgtgcc cttccgctgg
     5641 aacagggagg ccagacaccg gccgtcgcgc tcaccgcctt cgcgcggatg gaggaccgca
     5701 cccgggcgct gctcgccggc ttccagatgc acgttcccaa gcccatcgag ccggcggagc
     5761 tgatcatcgt cctggcctcg ctcaccgggc ggtacccgcg ggtggtggac tcggcgttcc
     5821 aggccgtccg ctagaaggac cgggcaggcg ccggcggggg tgccgccggc gcctcatgcc
     5881 gcgctcagat cgtcttcctg cccggcaggt cgaagcgatc cgcgttcatc accttggtcc
     5941 aggcgtcgac gaagtcctgc acgaagtgcg cggtgccgtc gctggccgcg tagacctccg
     6001 ccagcgcgcg cagctgcgag ttggagccga agacgaggtc ggctacggtc gccgtccagc
     6061 gcaggtcacc cgtggcgcgg tcgcggcctt cgaacacgtt cgacgtcttc tccgagcgct
     6121 tccacgcggt gcgcatgtcg agcaggttga cgaagaagtc cggcgtcagc tggcccgggc
     6181 gcttcgtgaa caccccgtgc ggcgtgtggc cgtggttgac gtccagcacg cgcagcccgc
     6241 ccacgagcgc cgtcatctcc ggcgcggtga gcgtgagcag gctcgcgcgg tcgatgagcg
     6301 ccgcggcggt cgtcgcctcg gcgcccgccc ggacgtagtt gcggaacccg tccgccgcgg
     6361 gctccaggac caggaacgat tcgacgtccg tctgctcctg cgacgcgtcc atgcggcccg
     6421 gcgtgaaggg cacggtgatc ttgtgaccgg cggcgcgcgc ggcggcttcg atgcccgcgc
     6481 tgccgcccag cacgatcagg tccgccagcg acacccgctt gccgccgcgc tgcgcgccgt
     6541 tgaacttctg ccggatggct tcgagcttgg agagcacctt cgcgagctcc gagggctcat
     6601 tggcctccca gtccttctgc ggcgccaggc ggatgcgcgc gccgttcgcg ccgccgcgca
     6661 tgtcgctccc ccggaacgtc gacgccgagg cccaggccgt cttgatcagc tgctggatcg
     6721 acaggccgga gccgagcagc tcggccttga gcgcgtcgat gtccgtggcg tcgatcagcg
     6781 ggtggtcgac ggccggaatc gggtcctgcc agagcagctc ctccttgggc accagcgggc
     6841 ccaggtagcg ggacctggga cccatgtcgc ggtgggtgag cttgaaccag gcgcgcgcga
     6901 aggcgtccgc gaacttcgcc gggttggcca tgtagtcgcg ggagatgcgc tcatagatga
     6961 ggtcgaagcg cagcgccagg tcagcggtgg tcatcatcgg cgcgtggcgc ttcccgggca
     7021 cgtgcgcgtc cggcacggtg ccggcgccgg tgttgcccac gggcttccac tggtgcgcgc
     7081 ctgcggggct ccgggtcagc tcccactcat agccgaacag cacctcgaag taggtcatgt
     7141 cccacttcgt cggcgtgggc gtccacgcgc cctccaggcc gctcgtggtg gcgtgctcgc
     7201 cgacgccgct ctcgtaggtg ctcttccaac ccagccccag ctcctcgatg ttcgcgccct
     7261 cgggctccgc gcccacgtgg tgcaccggac ctgcgccgtg gcatttgccg aaggtgtggc
     7321 cgcccgcgac gagcgcgacg gtctcctcgt cgttcatcgc catgcgcgcg aacgtctcgc
     7381 ggatgtcgcg cgcggagccg acggggtcgg gcttgccgtt cgggccttcg gggttgacgt
     7441 agatgaggcc catctgcacg gccgccaggg ggtgtgccag ctcgcgctcg ccgctgtagc
     7501 gctcgtcgcc cagccaggtg gactccggcc cccagtccgt ggtgtgcggc tcccagatgt
     7561 cctcgcggcc gccgccgaag ccgaacgtct tcaggcccat ggactccagc gccacgttgc
     7621 ccgagaggat catcaggtcc gcccacgaca gcttgcggcc gtacttctgc ttgatgggcc
     7681 acagcaggcg gcgcgccttg tccaggttcc cgttgtcagg ccagctgttg aggggcgcga
     7741 agcgctgctc acccgagcgc gcgccgccgc gcccgtcgaa gatgcgatag gtgcccgccg
     7801 cgtgccacgc catgcggatg aagaacgggc cgtagtgccc gtagtccgcc ggccaccagt
     7861 cctgcgagtc cgtcatcaac gcgtgcaggt ccttcaccac cgcgttgagg tcgagcgtct
     7921 ggaactccgc cgcgtagttg aagtcctcga ccatcggatc cgacagcgag gaatgctggt
     7981 gcagcatcgc gaggttgagc tgctccggcc accactgcgc gttcgtgcgc gcgcggcggg
     8041 gtccgtgcgc gacagggcac ttcgcttcgt cgttcatgcg ggtctcctct gcggctggcg
     8101 cgcgggttcg tagcgcgccg ccgcgaccgc cgggggccgc gtggccgcag aggcccggga
     8161 ggcgttcgct accggaccca ctccccacgg cccgcgtggg agaccgttac gtggtgggca
     8221 tcaatgcttg cggcgcagga gcttgcgcag gcccgcgagc agcgcctcgc cgtcgggcgt
     8281 gcccaggccc gtgcacgcgt tccacagcgt ctcctcgctg gcgaagtacg cgccgttgcc
     8341 gccctgggtg atgcgccgga cgacggcctc cccctcggtg acgagcgtgt acagccgggg
     8401 gttgaggaag cccacgcgct cccccagcgc ctcgttgagg cggacgatga gcgcggccca
     8461 catgggcgcg gcggcgctcg tgcccgcggc cacgccctgc tggcccttga agacgatttg
     8521 atagccggtg tgcaggtccg cgttcgccgc gacgtccggc acgccacggc cggtgctccg
     8581 cgagacgtcg aacgcgccgt tcttccatga tgacctcacc aggtccggca cgcccatgcc
     8641 ctgctggtac aacggcagcg cgttcatggt gctgaccccg ccgctgctcg cccccgcggc
     8701 cgtggacatg cgccccagaa ggcccatgga catcgcctcg cccaggcggt tccacacgcg
     8761 ctcgtggtgg aggacgtcgc ccaccgcctc cagcgtcgtg ccgccgcagc ccagcaccag
     8821 cgcgctcgcg gcggggtagc tcgtcgcggc cagggtgatg gcgcccgtgg gcgacacggc
     8881 attcaccggc acctgcgagc ccaggtcgcc ggacgcggcg cacacggtga tgcccagcag
     8941 cgcggcctcg acgaagagcc gctcgaagac cccctcctcg ccctgctgga tgagcgaccc
     9001 ttcgtagaag gaccagctgg tggtcagcac cgacggccgg ttctcccggt cgctgagggc
     9061 ctccgccagc acgcggtggt agtcgcgcag cgagtagtcc ttcgagcccg cgttgtagac
     9121 gacgacgcgc gcggccggac acaccgcggc caccagctcc acgtccatgg tgacctccgc
     9181 gtcggaggcg gtgtggagga tccccacctt gttcggcccc acgttcacca ccggcgccgt
     9241 gcgcttcacc cccgcggact tcagggacgc ctccaggtcc gacggcctgt agccacccgc
     9301 cagctcgatg acgcccacgc actggccttc gccctggttc tgggggtagc ggtagaggct
     9361 ggccacctgc ggcgccgtgt acgagcgcaa cccgacctgc ttcgccgcct cgcgagggat
     9421 gggcagggac gccgcgttgt gggtgacgag cggccgggtg tccaggccca gcacccactc
     9481 caccacaccc cgcagcgcgc gcggcagggt caccggcttc gtgtggctca ggtaggacgt
     9541 ccgcccctgg gtgaagcgcc gcaggtccac gccgaaggcc ttgcacatcg cggccgcggc
     9601 cccctggagc gtgacgcagc cccggtcacg ccgctcggag gtgatggtca ggcggtggga
     9661 cttcgcgaag cgccgcacgg cggccaggtg cttggggggc gtgccgtact tcgcctcgaa
     9721 ctcctcgtgg gtgagggggc ggcgcggggg gttcgcgcac aactcctcca cggtgggcag
     9781 cggcgcccca tgtcgcagca ccagggtcac ctccacgagg ccggtggcgg cgcggctccg
     9841 gagcgggagg tggagagacg ccggagacac acgcgcgctc tgcgccaggg ggatgcgagg
     9901 ggccatgcgc ggcgttctac cacgcgcggc ccgggcgccc ggaaggcggg ccgggtcata
     9961 tccatggacg cgggccccgg ttaggctcgc ccgcctgccc atggaccgag tcctccgcat
    10021 caagccccac ctgcgcgccg aggtgctcga ctcgcgacgc gtcttcctcg tcggggagcg
    10081 cgcccagttc ctgctcgagg gcgagctgca cgcgagcatc gtgcccctcc tggatggcga
    10141 gcgcaccgtg gcgagcgtca tcgccgcgct ggcggggcgg gcctccgcgc cggaggtgct
    10201 ctacgcgctg tcgctcctgg aagagcgcgg gcacgtggag gaggcgcatg acgtcttcga
    10261 cgccagcgtc gccggattct gggagtcgct gggagtgggc gcttccaccg cggccgggcg
    10321 gctgttggac atgtccgtcg ccgtgcgcgc ggtggcaggc gaggacgcgg agcggctgtc
    10381 ggaggcgctg cgcgacgccg gcctggacgt gcgcgacgac gccgagcgcc acgtgctgct
    10441 ggtggacgac tacctgtcgc aggaggcgct cgcgctggcg cgcgagtccc ggggcgccgg
    10501 cgccgcgttc ctcccgctga aggtgtccgg caccacgtgt catgcggggc cggtggtggg
    10561 ccccgagcgc gcctgctgga cgtgcctcac cgcgcggctg ctggacaacc gtcccatcga
    10621 gaagtacctc gcgcgaaagg gcattccccc gagcgccatc cgcccgccac gcacgggcct
    10681 gcccaccacc gcgcaggcgg gactgtccct cgcggcgacg ctcgtggccc gctgggtggt
    10741 ggacgggccc caggccgcgg gacagacgcg gctgtggacg ctggacttcg ccacctggaa
    10801 gctgcagtcg cacgcggtga cgcggcgtcc gcagtgtccg gactgcggag acccgcattg
    10861 gatggacgcg cgcgcgaagg cgcccctgga gctgacctca cgtcccaagc gcttcacgga
    10921 cgacggcggc caccgcatcc tcacgcccga ggagacctgg gagcgccacc gccacctcat
    10981 cagcccggtg acgggcgtgg tgagcgacct gcgcgcggtg ccgggcgacg caccgctggg
    11041 ccacatccag tccgcggtct tccgcgtgtg cccgtggacg gacgcgccgg cctccgacga
    11101 cttccaccgc gtggccagcg gcaagggccg cacggaggcc caggcccgcg cgggcgcgct
    11161 gtgcgaggcc ttggagcgct acagcgcggt gttccagggc gacgagccgc gcgtccacgc
    11221 gacggcctca cacctgggcg tccaggccgt gcacccggac gcgctccagc acttcagcgc
    11281 cgcgcagttc caggcccggt ccgaaggcgc gggccgccgc gacatgcgca ccgcggtgcc
    11341 gcgtccgtac gcggatcaac ccatggactg gagccccgcg tggtcgctca cgcatggcgt
    11401 ctcccggtac gtgcccacgg cgttcgcgta cctcttcgcg cccacgcccg cggacgggcc
    11461 gttctgcttc ttcaactcca acgggaacgc ggcgggcaac tgcgtggagg aggccatcct
    11521 ccagggcttc ctggagctgg tggagcgcga tgcggtggcg ctctggtggt acaaccgcct
    11581 gcgccgcccg cgcgtggagc tgcgctcctt cgacgagccc tggttcacgt ccgtggaggc
    11641 gcattaccgg tcgctgggcc tccggttgtc ggtgttggac ctgacgcatg acctgggcat
    11701 tccggtgttc gccgcgctcg cgtggtcgcc ggagcgcggg cgggcctggg ccgggtgcgg
    11761 ctgccacttc gacgcgaagc tcgccgtgca gcgcgcgctc acggaggtgg cccagtgcta
    11821 cgacccgaag gacctgaccc cgtcgccctg ggactcccgg gcgcatgacg acacccactg
    11881 gctcttcccc gacgacacgg tccccgcgcg cgttcgcgcc gacttcccgc gcgtatggca
    11941 cgacgacctg cgggacgacg tgcacgagtg cgtggcccgg gccgagcgcg tggggctgga
    12001 gacgctggtg ctggagcaat cacggccgga cgtgggcgta tccgcggtga aggtcatcgt
    12061 cccggggctg aggcacttct ggccccggct ggggcctggc cggctgtatg acgtccccgt
    12121 gcggatgggg tggctgaagg ccccgaagac cgaggcgcag ctcaaccccg tgcccttcta
    12181 cttctgagcg atggcaccgc ttcccgaacc caagccccgc gtcctgctga tccaatgcgg
    12241 ccccgaccgg cgccacgtgg accgcgagac cgaggacttc gaccccgagc gcggcctggt
    12301 gaagcgcgcg acgatgacgc cgctggcctg cgcgacgctc gcggcgctca cgccggaccg
    12361 cttcacggtg gacatctggg acgaggagct gcacggacag ctgcgcgcgg acaccgagct
    12421 gccggactac gacatcgtcg gcgtgtcggt catgtactcc gcgctcacgt accaggcgcg
    12481 cttcctgggc ggccatttcc gggaccgggg cgccaccgtg gtcgcggggg gccccgccgt
    12541 ctccgccgcg ccggaggact accggggctt cttcgacgcc ctcttcgtca acgaggccga
    12601 gcgcacctgg ccgcgcttcc tcgcggactg gctgagcggt gagtacgcgc ccgagtaccg
    12661 gcagctggac aagccgtcgt tgagcgaaag ccccctgccc cgctgggacg ccgtcgcggt
    12721 ggacctcccg cgctacgcgt ggggctccgt gcagacgacg cgcggctgtc ccttcgactg
    12781 ctccttctgc gacgtcatct acctgtacgg ccgcaagcag cggcacaagc cggtggagcg
    12841 cgtcctggac gaggtgcgcg cccacgcggc gctcggggcg gagggcgtct tcttcgcgga
    12901 cgacgagttc atcggggacg cggcgtacgc gaagcaggtg ctcgcggggc tggtgcccct
    12961 caaccgcgcc ctgccccgcc cgctgcgctt cttcacccag gtgacgatga acctgagccg
    13021 cgacgccgcg ctcctggaag gcatggcgga cgcgaacttc tacaccgtcg tcctgggcat
    13081 cgagtccttc gaccccgccg cgctcaagga ggcgcagaag caccagaacg tgcgcgcgga
    13141 cctggtggga gacctgctgc gcatccaggc tcacggcatc gggccccggg gcagcttcat
    13201 cgtcgggttc gaccacgaca cgcccgcggt gttcgactcg ctgcacgcga acatccagcg
    13261 cacgcacctg ccctgggtgg tggtcgcgcc cctccaggcc ccccgtggca cgaagctgtg
    13321 gacgcggctg cgcgcggagg gccggctcgc cacgccccgc aaggcgcacg cgaaggaccg
    13381 gggcgccatc gtgctcaacg tgatgcccct gggcatgacg cggccccagc tgctcgaagg
    13441 cttccgggac ctggtggagc ggctgtcctc ctgggacgcc gcctgcgagc gcatccgcgg
    13501 cttcatctcc ggcatccagc gcccgcccca ggtgcgggaa gtcccctggc cggaggccgt
    13561 caccgaccgc ttcctgcgcg aagccaccgc cgcctgggcc ctgactccac cggagcgcca
    13621 ggccctggga gacacgctcg cgcaggtgcg ccgcaccgcc ccggcgatgg tgccgcgcgc
    13681 ggtgttcttc ctcgcgcgca accagaacga gcgccgccgg cacgagcgcc tcttcacgga
    13741 cttcgacgcg gtgctcgccg ccgagcgaca gggcgacctc gtcccggact cgcagcccgt
    13801 ctacgtccct cccggcttcg ccgcggcgat gcgcgacgtg ttcccggacc tcttcgtgcg
    13861 cctgagccgc gacctgccgg accgccgcga cgtgccggag gcctcgcgcg acgtgctggt
    13921 ggacttcgtc gcgcgctggg gtgaaggctt ccaggtgctc cagccgcagc accatgaatt
    13981 cctgcgcgag ctgtgcgacc gcgaggtggc ggcgcggggc ggacggccgg gcacgctgga
    14041 ggcctcggag gagcaggccc tgcgcacgca ggcgcgccgc accggcctcc tggaagcgct
    14101 gctcaaggac gtgcgcgatg aactggcgag ctggggaccc tgacgcatgc gcgacggcct
    14161 tcgcatcttc gacgcggacc ggcatgtcct ggagccgctg agcctctggg cggagcagtt
    14221 ggagccccgc ctgcgccgcc acgcgccccg cccgggccgc ctccccgacg aaacgctgga
    14281 ggagcgcctg gagcggctgg gcccccaggg cctcctgccc gtgttgccgc tgcccgaggt
    14341 ggacggcaag ccgctgtgga accacatgcc ggagaaggcg tgggtggagt tctccgcgcg
    14401 ctcctacgcg cagctggggc gcaatgaact gttgcagcgg ccagacgtgt acctggccca
    14461 gatggatcgc gacggcgtgg acatggcggc cctcttcccc acccatgcgc tgctcctgga
    14521 gggcttctcc cccctgaagc cccacgtcgc caccgcgttc gcgtccgtct acaacacctg
    14581 gctgcacggc ttctgcgcgc acgccccgga gcgcctgcgc ggcgtggggc tcatcagccg
    14641 gcacgaaccg gaggccatgg tcgcggaggt ccgccgcgtc gcgggcttcg gctggcgcgc
    14701 cgtgatggtg cgccccaacc ccatcggcgg ccggctcctg tccgacgccg cgtacgagcc
    14761 cttctggtcc gagtgcgaga gacgctcact cgcggtggtg ctccacggca gcggccacgt
    14821 ctacgtgccg tccgcgggcg cggaccgctt cgacacccgc ttcgccaacc acgtctgcgc
    14881 ccaccccatg gagctgatga tggggctgct cgcgctgctc caggggggcg tgctggagcg
    14941 gcaccccgcg ctgcgcattg gcgccatgga ggccgggtgc ggctggctgc catactgggc
    15001 gtggcggctg gacgaggaat atcgcgctgt gggtgcagag gtctccgcca ccatccgaca
    15061 gctcccttcc tcctacttgc gccagcactg cttcgtttcc gtggagccgg acgaaccgta
    15121 cctggctgac gtggtgcgcc acctcccgga ggaccgcctc gtcttcggca gcgacttccc
    15181 gcacctggac cacggcgagg atgtgctggg gtccctgctg tccttgcgtg acgcgatgac
    15241 cgaaagtcgt ctacgaaagg ttctctggga aaacccgact cggttctacg gtgtggaacc
    15301 gtgaggccgc acgaatgaga ttgtcgctcg ccgaaggtgt ggcgctgcgt tgccccgacg
    15361 cggaggacgc acgcgtggag ggccctggcc gctcgctgcg gttggggccg ctggcgcccg
    15421 gcgtgcgcgc cgtcttcgag tcgctggcgg atggaggcat ccacgagtcg gaggtgcccg
    15481 ccgccgcggg ccgggacacg acgctcgcgt ggtactggct ggacctggcc ggcgacgggg
    15541 gcctgctgtc gtggacggtg gaggagcggg gcaacctgct gttgacgctg acgcccgcgt
    15601 ccgcgtcctt cctgcgccac cgcgccacgt tcgacgccgc ccagccgctg cagctgtccc
    15661 gcttcgcgca cacgcgcatg gccgagggcc gcgccgtgct ggactgcccc acggtgcacg
    15721 ccaccgccgc gctgcatgac cggcgcgtgg tgtcgctgct cttcgacatg gcccggccca
    15781 cgctgctggc gcggctcaac cagttcaaca ccggcatcga gtccttcacc ctgcgcgagc
    15841 tggtgcgcct gttggcggag acgggcatcc tggtccccaa cggcctggac gtgccggcgt
    15901 cggaagagac gcagacggcg ctcaagcagt gggagccgca cgacctgctc ttccacctgc
    15961 gctcacgcgg ctggggccac cagacgcgcg cgggggccac ctaccgcttc cggggcgagc
    16021 tgcccaaccc tcccgccctc aagccctcca tcatccagga ggcggtggag ctgtaccgcc
    16081 cggacatgga ggcgctgcgc gccgaagacc gctccttcac ggaggtgctg gaggcacgcc
    16141 gcagcctgcg gggccgtggc gccagtccgc tcaccctgcg gcaattggga gagctgctct
    16201 accgggccgc gcgcgtgcgc gacgtgcgga ccacccagga cggtgaaatc acggaccggc
    16261 cctacccggg cgcgggcgcg gtgtacgcgc tggagctgta cccgctggtg ggcgagtgcc
    16321 agggcctggc ccccggcgcc taccactacg acccgctggg ccaccggctg gagaagctga
    16381 gcggccccac gccggagttc cacgcgctga tggatgaagc ccgcgcgccg gcggagccct
    16441 tcgagcggcc ggaggtgctg atggtggtgg ccgcgcgcgt gccccggctc gcgtggaagt
    16501 acgagacgct ggcgtactcg ctggtgctgc aggacacggg agcgctggtg cagacgctct
    16561 acctggtgtc caccgcgctg ggcctgcggc cctacgcgct gggccggagc gatccggact
    16621 tcttccagcg cgtggcgggc gtggacggct tcggtgaggc ctccgtgggc gccttcgcgg
    16681 tgtcgggggg agacgctccc gcccgggatc gctgaggcgc ccccccggcg ccgctcacgc
    16741 cggcttcagc agcaggggct gccgcagcag tgcgagcggc cgtaggtgtc ggtgaggctg
    16801 gagagcgcca cggcgtggtc cgccacgtcc gccggcttct tgggcaggtg cagctccacc
    16861 tccgcgctgt tcaccttcca ggtgccgtcc gccgcggcgt ccttctccgt ggtggggacg
    16921 accttcaggt ggatgctggc cggcaggtcg aagtcgaagc gcttcttgag ggcctcgcgc
    16981 gggttcttct gcagcgccgc ctcgaactcg ggctccttcc acgcgagcgc gacggcgcgc
    17041 atccacacgg cctgccagtc attcaccgag gcctggcccc ccgtgctccg cgtgggcttg
    17101 cgcgccaccg gacgggcccg agcgggcgcg gccttcgact ccggcttctt cttgctcatg
    17161 tcagcagtct cctcccagcg ctcccaacaa cgcgcgggcc tctgagatgg gcggggttcc
    17221 ccatccttcg gagaaggtac tgtagaccgt ttgcagccgc tgccgggctt cttcctgccg
    17281 ccccgaggcc tggagcagcc gtgccaatgc cgtcacggcc tgcagctccc gcatccgagc
    17341 cccttgtgcg tgcgccacgt ccgcggcctg ccggaagcac gactccgcgg acagtgcagt
    17401 gtttccatcc cgctggagca gcacctgtcc cttgacgcgc agcagcttgg actcgtggta
    17461 cgcctcgccc agggcctgcg cgcgctggag gccgcgctcc acggtggcga gcgccgcctc
    17521 caggtggccc agctccagct ccagctccgc gagcatgccg tagtaggccg gctggtccat
    17581 ctccgtgccg aacgcctcgc gcatcgccac gccgcgccgc atggcctcca ggtccttcgc
    17641 cgcccagccg cgcaggatgc ccacgtaggc ggactgctcc agcaggccgt agcggtgcga
    17701 cagctccgag tgctgcgcga cgaggttgag cgcctccgtc cggtcgccgt gctcctgcgc
    17761 catcagcagc aggtagatga acgacaggcc cacgctggtg ccgtgcttca actcgcggcc
    17821 ccacgccacc gcggcctcgc cgtgcgcctt cgcctggtcc gggaagccca acagccacag
    17881 cccccggcac agcacggact cgccgcccac gcgcgtgtcc tggccgtaga ggatgtggtg
    17941 catccggtgc gcgaccgggt cgaacagcga caggcaccgg tccgccttcg ccttcgcctc
    18001 gcccaggcgg ccttccagca gctcgatgtt ggagaggatg gtgagcgcca ccgcctcctg
    18061 ccccgcgtcg ccattgtgct gcgccagtgc caccagccgg tccagcagcc cgcgcacccg
    18121 gcgctgatct ccccccaggt ggtagaagat ggagaggacc cacagcgtcg gggccgcgta
    18181 ggggctctcc cccacggtga agagcagctc cagcgagcgc tcggccacgg tgcgcaggtc
    18241 ctgtgagcgc cagccctgcg aggacatcag cgccggcgcg agcacgccgt tgaggcccag
    18301 ctcctgctgc gcgcgctcca ccgggtcttc gatggcgtcc agccacgaca ggcccagccg
    18361 ggcgaagagg atggcctcca ggtacgcgga gcgcaccagc gcggcgaacg cggccttctg
    18421 cgcgtagacg atggccttgc gcttcaggtt cgcggcggac aggtgatgcg cgagcaggtc
    18481 cgggcgcgac tccgcctgct ccgggaagtg cgcctccagc gcctccgccg tcttcgcgtg
    18541 cacctgctgc cggtaccgct tgagcatgga gtcgtaggcc gcgtcgcgca ccagcgcgtg
    18601 cttgaagagg tagacgggcc ccttcggccg gcgcttgcgg tgcaggagcc ccgaggccac
    18661 cagccgctcc aggtccgcgt ccagcgcctc gggcgtcagc gggctcacgt ggcgcaagag
    18721 ctcatgggtc agctcgcggc ccagcacgga ggccacctgc gcggtctcct tggcgcggcc
    18781 cagccggtcc aggcgggcga cgagcaggtc gcgcagcgtg ccgggcaccg cggggcccgc
    18841 cttgcccgct tccagcgcga agcggccctc gcgctccacc agcgcgccgg actcgcgcag
    18901 cgtgcgcacc agctcctcca cgaacagcgg gatgccgtcc gtgcgggtga cgatctcctc
    18961 caccgcctcc ggcgacagcg gaccgcccac ggcggaggtg gccagccgct ccacctccga
    19021 gcgccccagg gtgcccagct gcacctgcgt cacggacgac gcggcccatg gcggctcgaa
    19081 ctccggccgg gcgctgaaca cggagagcag gcgcgacgag gacacctcct ccaccagcgc
    19141 cttgagcagc tccagcgtgg acgggtccgc ccagtgcagg tcctccagcg acagcaccac
    19201 gggctggcgc tcggccatcg cggcgaggag cgcgagcagc gcgtcgcgcg tgagctcccg
    19261 gtgcttcagg ggcgacacgt ccagcggtgc ccagcgctcc ggcggcagcg gcagggacag
    19321 gagcggcgcg aacaggggca ccgtctccgg cagctcgaag ctgtagccgg acagcagcgc
    19381 ctccaggccc gtgagccggg cctccggcga caggtcgcgg ttcgggtcca gcatccgtga
    19441 gagcagctcc accacggggg cgtacgcctg gccggagccg tccgccgtgc agcgggcctc
    19501 cagccacgtg tggggctccg cgcccagccg gtcacccagc tcgcgcatca ggcgcgactt
    19561 gccgatgccc ggctcgccgg agagcagcac cgcctgcccc tgccccgagc gcacctgctc
    19621 ccagcgcgac agcaccaggt ccagctctcg cgagcggccc accagcgcca gcgtgtcgtc
    19681 ggtgccgctc cacgtcgcgt ccgcgccctg gagcgcgaac gtctccagcc ccgggggcaa
    19741 cagctcgctg ggcgccgcgg gcacgctctc cagcgggaag tgcttgcgca ccagctgctg
    19801 cgtgtcgccg gtgaggagga tgacgcccgg cggcgcggag gtggacagcc ggaacgccag
    19861 cttcggcgtg gtgccgacga cgaagcccag gccggagagc gtggggtccc gctgctctcg
    19921 cgacaccacc aggcccgtgt gcaggcccac gcggatctcc acccgcgtgc cgcgctcggc
    19981 ctcgatggcc cggccgcgcc gcttcacctc ggcgaccatg tccagcgccg cctgggccgc
    20041 gcgccgcgcg tcgtcctcgc gcgccgccgg atagccgaag tagaagagga cgatgtcgcc
    20101 cagcgcgctg gcgatgtggc cgttgtggcg ccgggcgatc tcgatgcaga cctcctgctg
    20161 ggcgcccagc acgtggtcca gctcctcgat gtccaccggc cccggcgtcg tctgcgtggc
    20221 ggacagcgtg cagcagacca ccgtgagctg gcggcgctcg ccctccgccc accggcgcga
    20281 ccgcgtggac agcgcgttgg gcgtgcggct ggacagctcc accgtcgccg tctccgcgtt
    20341 gggggccgcg ggctggatgc gcaccggagc ctgccggcgc ggcaggttgg acacgtccac
    20401 cgcctccagc tggcgcagca gcacctccgc ggccacggtg cgctgggacg ggtccttcgc
    20461 ggtgacgcgc tggagcagct tgcccagcgg gtgcgcggcg atgaccggcg gaatgggcac
    20521 cggctccgtg gacagctgct ggaagatgac ctccgccacc gtggcggcct cgtagacgcg
    20581 ccggccggtg aggcactcca ggaacaccag gccccacgcg tacaggtccg agcgcggcgt
    20641 gggcgcctgc ccgcgaagct gctccggcgc cgcgtacgac ggcgtgccca gcgactcgtt
    20701 ggtggacgtg atgcgcggct gtccctcctc gcgcgcgatc tcatccgtca ccgacccgat
    20761 gccgaagtcc agcaccagcg cgttgcgccg ggcgcccgtg ggcacgacca tgatgttcgc
    20821 gggcttcagg tcgcggtgca ccacgttctg cgcgtgcgcg cacgccagcg cgtccagcag
    20881 ctggagcatc aggtggcgcg cctccaccgg atccagcgcg ccctcctccg cgagcacctg
    20941 cgccaggttc ttgcccggca cgaactcgaa gatggagtag acggcgccgc cctgcgcccg
    21001 gcccgaatcg atgagccgca cgatgttcgg gtggtgcatc tgcgcgcaca gcttcatctc
    21061 gcgctcgaag cgcgcgctgc ggcgctccac ggactccggc gtcgcgccgt ccgtcagacg
    21121 caggagcttc accgccacgt tctggccggt ggtcacctgg cgggccttgt agacgcggcc
    21181 gaagccgcct tcgcccagct ccgacagcag ctcataccgg ccctggaagg cttccagcag
    21241 ctggggatcc atgaggttct tcatcgcgct cccgagcctc gctccattga tgaccgtccc
    21301 ccccgcctgg gcagggtgat gacgaactcc gtgaactcac ccggcaccgt ctccatgcgg
    21361 aacgtgccct ggtggccctg cacgatgatg tcatgactga gcgacagccc cagccccgtc
    21421 ccctgccccg gcggcttcgt cgtgaagaag gggtcgaaga ttcttctcgc actctccgag
    21481 gggatgcccg gcccgttgtc gcgcagccgg acctccacct gctcaggacg cgcgagggtg
    21541 cgaaccttga ggaccggcgc gtacgccgcg ccctgcgcct ggcgcttctg acgcatggcg
    21601 tagagcgcgt tgtccacgac gttgatgatg acgcggccca cgtccgcgcg gctgagctcc
    21661 agcggcccca cggccgggtc gtactcggcc tccaggcgga cggtcagggc ctcgccgcgc
    21721 atgccgccca gccccagggc cacgctctcc gccaccaggg cgttcaggtc caccggctcg
    21781 cgcgggccgg gggcgcggcg cgcgtgctgg agcatgccct ggatgaccgc gtccgcgcgg
    21841 cggccgtgct cgtggatctt ctggacgttg gtgcgcaggc acacgagcgc ctcgtccacg
    21901 tcgcgcacgc tgtccggcgt cagccgctcc cgctgcggct ccagcacgcc ggccaggtcc
    21961 tccgtgaggc ccacggagag cccggcgaag ttgctgatga agttgagcgg gttgcgcagc
    22021 tcgtgcgcca tgccgcccac cagcgccgcg agcgaggcca gcttcgcgtc catgatgagc
    22081 tgcatgcgct gcaccgtctc ctgctcgatg cggcggtaga gccgcgcgtt ctccagcgcg
    22141 agcgccgcct gtcccgcgaa cgcgacgagg aagtccaggt cgtcctcgga gaagctcttg
    22201 ggcgtggaga cgttgtccac gtacagcacg cccagcacct cgtcgcgcgg cttgagcggc
    22261 acgcacatgg aggcgcggat ggagctgaag atgacggact ccgcggcgcc caggcgcgga
    22321 tcattcaccg cgtcggagaa gagcgccgcc acgctccggc gcagcacgaa gtccacgatg
    22381 ttctggctgt agatgggccc gcgcacggcc gcgccctccg ccgtcttggt cacgcgcggc
    22441 tccagcctcc cggtggcctc gtccatcagc aggatgacgc cccggtccac gcggaggatc
    22501 tggaacgcca ggtccagcac cttgccgggc agcgcctcca ggtcgtccgt gacggagagc
    22561 agcttcgcca cctcctggag gatgcgcatc cgctcgcgcg agcgcgtggc cgcgctggcg
    22621 gcctccaccg ggggcggctc ctgcccggac accgcctgca ccagcgtctt cagcggcacg
    22681 cgggtgagcg cgcgcgtgag ctgcgggcgg ggctcgtggg ccgccgcgcc gggcgggccc
    22741 gagggcgcga ccgggggcgg ctcgtgggtg agcaggaaga cgagctcgcc cagggtcagc
    22801 gtgtcgccgg ggcgcagctc cttgcggcgg atctgcacgc cgttgacgaa ggtgccgttc
    22861 ttgctctgga ggtcggtgac gaagaagcgc ccgtcggagg actcgatgcg ggcgtgctgc
    22921 cgcgacaggc tgcggtgggg gatgcagatg ccctggtcgt ccgcgcggcc aatggtgatg
    22981 ggcgcgtccc ccagcgggta ggacagctca tccggctgcc ctggattgta gacgagcatc
    23041 ggcacggcct tcggaccccc tccgggtcgc gagcctaacc gaaaagcggc ggccggaacc
    23101 ggcccggccg cctcaggcgg cgctggcggc gctggccagc agcccccggt cccgcagcgt
    23161 gtcgaggatg cgctccagcc ccgcctccac cgtctccgcg tcggagcgga cggtgatttc
    23221 gggggactcg ggcggctcgt aagggtccga cacgccggtg aagtggggaa tctccccggc
    23281 cagggccttc ttgtagagcc ccttcacgtc gcgggcgatg agcgcgtcca ggctggcctg
    23341 gacgtagcac tccaggaacg ggatgccggc ctgggtggcc agggcgcgca cctcgtcccg
    23401 ggagctcttg tacggggaga tggcggcggt gatgacgccc acctcgtgct tcgcgagcac
    23461 ccgcgccacg tagccgatgc gccggacgtt ctcctcgcgg tcctcgcggc tgaagcccag
    23521 accgcgggag aggtacgtgc gcacctcgtc cccgtcgagc agctccacgc gctgcacggg
    23581 cgagagctgc cgcgccaccg cggcggacag cgtgctcttg cccgcgccgg acatgccggt
    23641 gaaccagagg atgaagcccg gacgctgttg catggccact ccctacctgt ccaccgcggg
    23701 gccgttgatc atcccggcgc ccacggtggc gttggtgctt tcgtcgatga ggatgaagct
    23761 gccggtgctg cggttgcggc ggtactcgtc gaagaacagc ggcaccgtcg tgcgcagcgt
    23821 cacccggccc acctcgttga gcttcaggcc cgggctctgc tcgtcgcggt gcagggtgtt
    23881 gacgtccagc cggtagtgca gctgcttcac catggcgcgc gccatgcggg tggtgtgctt
    23941 gatggccagc cgggaaccgc tgctgagctg cgaggactcc gacagccagc acaccatcgc
    24001 gtcgatgtcc tggctcgcgg tgggcgggtt gcccgggcgg cacagcatgt cgccgcggct
    24061 gatgtccagc tcctcctcca gcgacacgtt caccgacatg ggcgggaacg cttccttcag
    24121 cggcttgccc gccagctcca gcgccttgat gcgcgtggtg aagccggacg gcatcaccat
    24181 cacctcgtcg cccacgcgca tcactccgcc caggagctgc ccggagtacg cgcggtagtc
    24241 gtggaacttc ttcgcggacg ccggacggat cacgccctgc acggggaagc gcaggtggat
    24301 gaggtcgcgg tcggacgcga tgtgcacgtt ctccaggtgg tgcaggagcg tggggccctg
    24361 gtaccagggc atcttctccg agcgcgtcac cacgttgtcc ccgcccagcg cggagatggg
    24421 gatgaacgac aggtccgtca cgtccagctt catggagaac tggcggaact cgtcccggat
    24481 gcggtcgaag acgcccgggt cgaagtccac cagatccatc ttgttcacgc acagcaccag
    24541 gtgcggcacg cgcaagagcg acgcgatgaa cgcgtggcgg cgcgtctgct ccagcacgcc
    24601 cttgcgcgcg tccaccagga tgagcgccag gtccgccgtg gacgcgcccg tcaccatgtt
    24661 gcgcgtgtac tgcaggtgtc cgggcgtgtc cgcgatgatg aacttgcgct tctgggtgga
    24721 gaagtagcgg tacgccacgt cgatggtgat gccctgctcc cgctcggcct tcaggccgtc
    24781 caggagcagc gccaggttga cgtactcgtc accccgggcc tggctcgtgc gctccactgc
    24841 ggcgagctgg tcctcgagaa tggacttcgt gtcgtacaac agccgcccga tgagggtgct
    24901 cttgccgtca tccacggagc ccgcggtcgc gaatctcagc agttccacta gaagtatccc
    24961 tcgcgcttgc ggtcttccat cgccgtctca gagaacttgt cgtccgcgcg gctggcgccg
    25021 cgctcggtca cgcgggaggc cgtcacctcc gcgatgacct gctccaccgt ggacgcggtg
    25081 gacggcacgc acgcggtgca cgtcatgtcg cccacggtgc ggaagcgcac cgtctccgtc
    25141 gtcaccgtct cgccgggcat catggtcatg aagggcgacc aggccatcag catgccgtcc
    25201 cggcggaaca cctcgcgccg gtgcgtgtag tagatggacg gcagcgccac gttctcccgg
    25261 gcgatgtact gccagatgtc cagctcggtc cagttggaca gggggaagac gcgcaggtgc
    25321 tcgccccggc ggtggcggcc gttgtagagc gcccacagct ccggccgctg gttcttcgga
    25381 tcccactggc cgaactcgtc gcggaaggaa tacacgcgct ccttcgcgcg ggccttctcc
    25441 tcgtcgcgcc gggcgccgcc gaagacggcg ttgaagccgt tcttctcgat ggcctccagc
    25501 aggggctgcg tctgcaaccg gttgcgggac gcgcggggcc ccttctcctc cgtcaccttc
    25561 ccggcgtcga tggcctcctg cacggacgcg acgatgagcc gcgcgcccag ctccgccacc
    25621 cgttcatcgc gatactggat gacctccggg aagttgtgac ccgtgtccac gtgcatcagc
    25681 ggaaacggca gcggcgcggg ccagaaggcc ttcaccgcca ggtgcagcat caccgcggag
    25741 tccttgcctc cggagaagag cagcaccggc cggtccagct ccgccgcgac ttcccggatg
    25801 atgaagatgg actcggcttc cagcgcctca agatgtgaaa gctcgtagct cacggccaag
    25861 caagctacca caacccgtcc cacgcccaac cgtgcccatg aaagtttccg cgtccaccgg
    25921 cgctgagaca cgccggatgc gacatgccgg agggggcggt gaaacatggc cggacgacct
    25981 gacgggatgg atgtttcacg catccttccg cgtgcccgtc cccggccttc accctgcgtg
    26041 cgcgggggag tttcgcgcgg ggggcgcatg gtatagacgg ccgcgccatg gcaagcgcct
    26101 cccctcccgt cctcgaccgc tggttcccgt cccgcaagcc gcttccggag ccgcgcctgc
    26161 gcctgttctg cctgcccttc gctggcggca gcgcggccat ctacaccccg tggttgcatg
    26221 cgctgcccac gggcgtggag ctgtgcgcgg tgcagctgcc cgggcgtgag cggcgcctga
    26281 tggagcccgc gctcaagacg ctgccggagc tgatggacgt gctgatgccc gcgctgacgc
    26341 cgctgatgga ccggcccttc gcgctgttcg gctacagcat gggggcgcgc atcggcctgg
    26401 aggtggcgcg caggctgaag cgccagggcg gcccgaagcc gctgggcttc atcgccgcgg
    26461 cggcgccccc gccgtcgcac aacgaccgcg agcccatcca cacgctgcct gacgcggggt
    26521 tcatcgcgaa gctgcgcgag tacgacggca cgcccgagga ggtcctccag cacaaggagc
    26581 tgctggagct catcctcccc acgctgcgcg cggacttcgg gctggcctgg gcggagaacg
    26641 gccaggactc gggcccgctg gacatcccgc tgtccgtgta cgcgggcaag ggggacaagc
    26701 acgtgggcct ggaca
//
