LOCUS       NZ_CP079946            10873 bp    DNA     circular CON 18-AUG-2024
DEFINITION  Corallococcus sp. EGB chromosome, complete genome.
ACCESSION   NZ_CP079946
VERSION     NZ_CP079946.1
KEYWORDS    RefSeq.
SOURCE      Corallococcus sp. EGB
  ORGANISM  Corallococcus sp. EGB
            Bacteria; Myxococcota; Myxococcia; Myxococcales; Cystobacterineae;
            Myxococcaceae; Corallococcus.
REFERENCE   1  (bases 1 to 9431171)
  AUTHORS   Zhao,Y. and Cui,Z.
  TITLE     Whole-genome sequencing of Corallococcus sp. strain EGB reveals the
            genetic determinants linking taxonomy and predatory behavior
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 9431171)
  AUTHORS   Zhao,Y. and Cui,Z.
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2021) College of Life Science, Nanjing
            Agricultural University, No.1 Weigang Road, Nanjing, Jiangsu 210095,
            China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: FALCON v. MAY-2020
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 113.0x
            Sequencing Technology             :: PacBio RSII
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_019968905.1-RS_2024_08_18
            Annotation Date                   :: 08/18/2024 04:02:55
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,752
            CDSs (total)                      :: 7,680
            Genes (coding)                    :: 7,614
            CDSs (with protein)               :: 7,614
            Genes (RNA)                       :: 72
            rRNAs                             :: 3, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 3, 3 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 66
            CDSs (without protein)            :: 66
            Pseudo Genes (ambiguous residues) :: 0 of 66
            Pseudo Genes (frameshifted)       :: 12 of 66
            Pseudo Genes (incomplete)         :: 62 of 66
            Pseudo Genes (internal stop)      :: 2 of 66
            Pseudo Genes (multiple problems)  :: 10 of 66
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 09:46:24
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 5350396
            Orig. end                         :: 5361269
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP079946.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from College of Life Science,
            Nanjing Agricultural University, China.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..10873
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="22"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..10873
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..10873
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[5000:5873](+)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..5873
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     tRNA            complement(72..145)
                     /anticodon=(pos:complement(5350505..5350507),aa:Met,
                     seq:cat)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="KYK13_RS22025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /product="tRNA-Met"
     gene            complement(72..145)
                     /locus_tag="KYK13_RS22025"
     misc_feature    160..174
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 21.98"
                     /tool="antismash"
     tRNA            complement(216..289)
                     /anticodon=(pos:complement(5350649..5350651),aa:Met,
                     seq:cat)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="KYK13_RS22030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /product="tRNA-Met"
     gene            complement(216..289)
                     /locus_tag="KYK13_RS22030"
     gene            complement(392..2395)
                     /locus_tag="KYK13_RS22035"
     CDS             complement(392..2395)
                     /GO_function="GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014397285.1"
                     /locus_tag="KYK13_RS22035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="WP_223632647.1"
                     /transl_table=11
                     /translation="MSDEKSGGNSGGPGGFGPKKPKATFGDVMLGIPSGGQGNERGGGR
                     GGRDEKSGPGRGDRGPRDAQSQSRPQGEAPRGGGERGGGRGGERRGGGGERRPSGPMVV
                     VKRASGSIETRALEGEKPAEATATAEQTGADAQASAAPSPAPTPRQVTPAPAPSSPLYD
                     EVPETESFADMFEAQVKDGGAPGRRSVRVGEKVSGTIFQLGADTAFVSLDGAAKSEAMI
                     ELRELKDDEGILRFGVGDRLEAHVVEMGAKGIMLSRALAKGNASFAMLAEARASGMPVE
                     GLVLSVNKGGVEVAIGETRAFCPISQLDIRFVEKPDQFIGEKLQFRVTEVRDRNVVLSR
                     RSLLEDEQRKLAAETRKNLAVGKTVKGKVSGVRDFGVFVDLGGVEGMIPVSELSYTRVG
                     HPSDVVKQGDEVEVEILRMEEGQPNSPDKSKQKERITLSLRSRQEDPFKKALEEIKEGD
                     RMQGKVVRLQPFGAFVELRPGVDGLVHISALSDRRIAHPRDAVKEGETIWVSVEKIDAN
                     EKRIGLRRISEEEAQRPPEERPAKEAQSPAAPKEPAAPRPKVGAVVVGKVDRLEPYGVF
                     LAFPGGKGLIPASETGTDRGTDMRKHFSIGQELKVAIIDIDASGKIRLSIPAAIRAEER
                     AEVEAWQKTQQPQGGGKKGFGTFADLLSKLGK"
     gene            complement(2623..4260)
                     /gene="murJ"
                     /locus_tag="KYK13_RS22040"
     CDS             complement(2623..4260)
                     /GO_process="GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /GO_process="GO:0034204 - lipid translocation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="murJ"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014397286.1"
                     /locus_tag="KYK13_RS22040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="murein biosynthesis integral membrane protein
                     MurJ"
                     /protein_id="WP_223632650.1"
                     /transl_table=11
                     /translation="MLVAIGILASRLMGLVRERVFAHYLGNAEAAAVFKAALRIPNFLQ
                     NLFGEGVLSGSFIPVYAQLLGKKDTDEADRVAGAVFGLLALATGVMVALGMLATPLFVD
                     LIAPGFEGGERDLAVRLVRILFPGTGFLVLSAWCLGILNSHRRFLLSYLAPVVWNVVII
                     ATLLTVGSVHGGAGGRAAEEAVTEWLAYGVVLGSFLQFAVQVPTVMRLLGHFRPVLSLA
                     SASVRQVLKNFGPVVLGRGVVQFSAWVDTAFASLISNRALSSLLYAQTIYLIPVSLFGM
                     AVSAAELPEMARATAEGETQAHAKLRSRIDAGSRRIAFWVVPSAAALLFLGDLVSGALL
                     QTGRFGAADSRYLWYLLMGAAVGLVASTVGRLYASAFYALKDPKTPLRYAIVRVALGTV
                     KAWFLALWLPERLGLPRELGAAFLTLSSGVVAWVETTLLRRKLRSMVGPVGLPSGLLPR
                     LYGAAVVGGLVALAVKQGLTGLLGPMPGVAAEWGGALLVPPRLHPVVGLLATAVPFGVV
                     YFAVAAALGIPEAGAVFRKVGRRLGLAR"
     gene            4461..4940
                     /locus_tag="KYK13_RS22045"
     CDS             4461..4940
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013940154.1"
                     /locus_tag="KYK13_RS22045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ferritin"
                     /protein_id="WP_223632653.1"
                     /transl_table=11
                     /translation="MAGKSDTERSDVARIRAVLARELETINEYEAYAEDSSHPEVKAFF
                     LHLAAEEKEHVSEATHMLRMLDKGQDAHFAKPFVPGHFQAAAGGAPAAEPTVAPPPAPP
                     PAPPSVGRLANEPLTSLPPQRLIYGVPAPPPSANGHPLTIGSLRRGGGGGGGSGR"
     gene            5001..5873
                     /gene="encA"
                     /locus_tag="KYK13_RS22050"
     CDS             5001..5873
                     /codon_start=1
                     /gene="encA"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Linocin_M18"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014397288.1"
                     /locus_tag="KYK13_RS22050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="encapsulin nanocompartment shell protein EncA"
                     /protein_id="WP_223632656.1"
                     /sec_met_domain="Linocin_M18 (E-value: 4.6e-83, bitscore:
                     277.0, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPDFLGHAENPLREEEWARLNETVIQVARRSLVGRRILDIYGPLG
                     AGVQTVAYDEFQGVSPGAVDIVGEQETAMVFTDVRKFKTIPIIYKDFLLHWRDIEAART
                     HNMPLDVSAAAGAAALCAQQEDELIFYGDQRLGYEGLMTANGRLTATLGDWTAPGGGFQ
                     TIVEATRKLNEAGHFGPYAVVLSPRLYSQLHRIYEKTGVLEIQTISQLASDGVYQSNRL
                     RGESGVVVSTGRENMDLAVAMDMVAAYLGASKMNHPFRVLESLLLRIKHPDAICTLEGA
                     VPSAPPARR"
     gene            5898..7322
                     /locus_tag="KYK13_RS22055"
     CDS             5898..7322
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1112: sigma-54
                     dependent trancsriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013940152.1"
                     /locus_tag="KYK13_RS22055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="sigma-54 dependent transcriptional regulator"
                     /protein_id="WP_223632659.1"
                     /transl_table=11
                     /translation="MAKVLVIDDETNLRKVLAALLRRDGFDVTVAENGEQGLAEFHKNG
                     ADIVVTDLVMPKLGGMEVLSAVRAANPDVPVIIITAHGTVDSAVEAIKAGAFDYITKPF
                     DQAELSSVVAKAAKTNESAKRSVRADHKARSAIIGESPQIQDVYKIIDKVADTPSTVLI
                     TGESGTGKELIATALHGESSRRDKPFIKINCAAIPATLLESELFGYEKGAFTGAVTSKP
                     GRFELADEGTLFLDEIGEIPVEMQVKLLRALQEGEFERVGGIKTTRVNVRLVAATNRDL
                     QAEIEAGRFRKDLYYRLAVVPIVLPALRERRGDIPMLAQHFVDKYNRRLHKKIEGIADD
                     ALALLQAYAWPGNIRELENLIERVLLFADGPLITARDLPEPVRGGAGVQAGAPVAASLG
                     TLDVPVGEVGLKDIVRMKAAELERDLIVKKLEETGGNVTRAARLLQISRKSLQTKMKEF
                     GLRDTTPDGQEDGPDE"
     gene            7397..8431
                     /locus_tag="KYK13_RS22060"
     CDS             7397..8431
                     /EC_number="3.4.24.-"
                     /GO_function="GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014397290.1"
                     /locus_tag="KYK13_RS22060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="M23 family metallopeptidase"
                     /protein_id="WP_223632662.1"
                     /transl_table=11
                     /translation="MRPNLPTLGGPPKRNPFGPVVAVSVILGAAAGGVWWWKQRMADVP
                     MDVASQPASPQDAGTIAAAPVAPPAPTNDPVKAAGLERASIRIEGPLETALIQASDATV
                     GPALAQVVTRTLVWWVRVPGEILRGDTLDVLYQRRPNEEPLVYAVRFVSGKTGQTHRAY
                     RFTPAGEQNAHYYLPNGDELELRMEKSPIDSYEQITSLLRDGRGHKGVDFRAPVGTSVR
                     APFAGVIKRKNWNFGSNGNCFELVESGGKGRSALFLHLSELPKTIQPGLRVSAGQVLAQ
                     SGNTGHSFAPHLHYQLMSGDGRVLDPFDQHKTYRASLVATQKGAFDAEVQRLDGLLGTP
                     VAGK"
     gene            8510..9793
                     /locus_tag="KYK13_RS22065"
     CDS             8510..9793
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011553582.1"
                     /locus_tag="KYK13_RS22065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_223632666.1"
                     /transl_table=11
                     /translation="MHRFRAVIAALTLGVPFAASAAEITRIASAFEEDDPFDLFLDVGF
                     ERTQTRAKIVREQLTGGDVTNVPEVNELWYKGVDARLNLAVAFGLWKDLEFSFKLPIVF
                     QQNETWNFVSGTNQRNSTITNSCFNADGSPYSSEGCVGRLFQVPQESYRGGLGNVHFGL
                     AYAFFNQKKDDTKPTWIVGIDYEAPTAKQRDPSLDNTDPDGDRGNVGDRVHKYQLYTTF
                     SRKMGVAEPYFKASHTIPVRGPGAYSNCDQSGANPPNLGAPGNCYKEPWTRNETGIHAP
                     SQTALTFGMELVPFENATKSQKLILDLRMLGNYVGRGRYYNELTSALRKLLTSDDYFQV
                     GGQVGITARAAQAFTIHASGKFLYNTDHLLTTEAIGQDLNGDGTVDTAVGSPELNPTFD
                     WRYDLVSRRFRAIQSTTFRFDLGATFNF"
     gene            complement(9835..10668)
                     /gene="rsmI"
                     /locus_tag="KYK13_RS22070"
     CDS             complement(9835..10668)
                     /EC_number="2.1.1.198"
                     /GO_function="GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0000451 - rRNA 2'-O-methylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="rsmI"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TP_methylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014397292.1"
                     /locus_tag="KYK13_RS22070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="16S rRNA (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="WP_223632669.1"
                     /sec_met_domain="TP_methylase (E-value: 4.1e-30, bitscore:
                     104.1, seeds: 87, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAGTLYLVATPIGNLGDVTARALETLRTVGFLACEDTRHSRILLD
                     HFGITGKDLVSLPAFAEGQRAGRILDRIEAGEDCALVTDAGSPGISDPGEKLVAEALER
                     GLKVEPVPGPTALVAALSASGLPTGRFHFLGFLPRKGPERRAMLDEVAPLSATCVLYES
                     PRRLAETLVDLQEAWGDRRACVARELTKLHEEFVRGPLSTLVARYAAEETRGEVVVLVE
                     GRTGEQRWSEDEVRRALESGLARGEKLKPLSTELARRAGWPGQEVYRLGLGLKQR"
ORIGIN
        1 gcccctgagc ggcaagaaca gacgctgaaa agcgaaaggg ccccggtgtt tccaccgggg
       61 ccctctcaga gttgcggggg caggatttga acctgcgacc ttcgggttat gagcccgacg
      121 agctaccagg ctgctccacc ccgcgtcacc gtgctgcgat tctcgatttg aacacccggg
      181 atcgaaactt tcatttcgac cccgggctct tcaagttgcg ggggcaggat ttgaacctgc
      241 gaccttcggg ttatgagccc gacgagctac caggctgctc caccccgcgg cgagaacgag
      301 aggctaagta ccgaagcccc tcgctaccgt caacacctat ctcggcgccc gctcgcattg
      361 tcgcgaggcg cgccgagatg gcgtgacgtc actacttgcc caacttgctg agcagatccg
      421 cgaaggtgcc gaagcccttc ttgccaccgc cctgcggctg ctgcgtcttc tgccacgcct
      481 ccacctcggc gcgctcctcc gcacggatgg ccgcggggat ggacagacgg atcttcccgg
      541 aggcgtcgat gtcgatgatc gccaccttca gctcctggcc gatggagaag tgcttgcgca
      601 tgtccgtgcc gcggtccgtg cccgtctcgc tggccgggat gagccccttg ccgcccggga
      661 acgcgaggaa cacgccgtag ggctccagcc ggtccacctt gccgacgacg accgcgccca
      721 ccttgggacg gggcgccgcg ggctccttgg gagccgccgg ggactgagcc tccttcgcag
      781 gacgctcctc gggaggacgc tgcgcctcct cctcggagat gcggcgcagg ccgatgcgct
      841 tctcgttcgc gtcgatcttc tcgacggaga cccagatggt ctcgccttcc ttcaccgcgt
      901 cgcgcgggtg cgcgatgcgc cggtcgctca gcgcggagat gtgcaccagg ccgtccacgc
      961 ccggacgcag ctccacgaac gcgccgaagg gctggagccg gacgaccttg ccctgcatcc
     1021 ggtcgccttc cttgatctcc tccagcgcct tcttgaacgg atcctcctgg cgcgaacgca
     1081 gcgacagggt gatgcgctcc ttctgcttgg acttgtccgg ggagttgggc tggccctcct
     1141 ccatgcggag gatctccacc tcgacctcgt ccccctgctt caccacgtcg ctggggtgac
     1201 ccacgcgggt gtaggagagc tcggagacgg ggatcatgcc ctccacgccg cccaggtcca
     1261 cgaacacgcc gaagtcgcgc acgccggaga ccttgccctt gaccgtcttg cccacggcca
     1321 ggttcttgcg cgtctccgcg gccagcttgc gctgctcgtc ctccagcagc gaccggcgcg
     1381 acagcacgac gttgcggtcg cgcacctccg tcacgcggaa ctggagcttc tcgccgatga
     1441 actgatccgg cttctccacg aagcggatgt ccagctggct gatggggcag aaggcgcgcg
     1501 tctcaccgat cgccacctcc acgccgccct tgttcacgct gaggaccagg ccctccaccg
     1561 gcatgccgga ggcgcgggcc tccgcgagca tcgcgaagga cgcgttgccc ttggccagcg
     1621 cgcggctgag catgatgccc ttggcgccca tctccacgac gtgcgcctcc aggcggtccc
     1681 ccacgccgaa gcgcaggatg ccctcgtcgt ccttgagctc gcgcagctcg atcatcgcct
     1741 cggacttggc ggcgccgtcc agcgacacga acgcggtgtc cgcgcccagt tggaagatgg
     1801 tgccggagac cttctcgccc acgcgcacgc tgcggcggcc gggagcgcca ccgtccttga
     1861 cctgcgcctc gaacatgtcc gcgaaggact cggtctccgg gacctcgtcg tacagcgggc
     1921 tggacggggc cggagccggc gtcacctgac gcggcgtcgg ggccggcgag ggagccgcgg
     1981 aggcctgcgc gtcggcgccg gtctgctcgg ccgtcgccgt cgcctcggcg ggcttctcac
     2041 cctccagggc gcgcgtctcg atggagcccg aggcccgctt cacgaccacc atggggccgg
     2101 acggacggcg ctcgccgcca ccgccccggc gctcgccgcc acggccaccg ccgcgctcgc
     2161 cgccaccgcg gggcgcttcg ccctggggac gggactgcga ctgcgcgtcg cgaggcccgc
     2221 ggtcaccgcg gcccggaccg ctcttctcat cgcggccgcc acggccaccg ccgcgctcgt
     2281 tgccctggcc ccccgaaggg atgcccagca tcacgtcgcc aaacgtggcc ttcggcttct
     2341 tgggaccgaa accgccagga ccgcccgaat ttccgccgct cttctcgtcg ctcactgccg
     2401 agaccttccg ttgacgattc cggcccggga cttccttgaa gtcagggcct cttgaaaaag
     2461 gcggcgcact ctacacgcgc gccacgcccg gaggaagccg catgcggcca tcccctgcac
     2521 aaagggcctc ctatcgcaac ggaaaggggc ctgtcctgca ttccgtttga gcccccaggc
     2581 attgcctgga gggcagccat gccgccatgc gccgcgccgc gtctaccggg cgagccccag
     2641 ccgccggccc accttgcgga acaccgcccc cgcctccggg atgcccagcg cggcggccac
     2701 cgcgaagtag acgaccccga agggcaccgc cgtggccagc aggcccacca ccgggtgcag
     2761 gcgcggcggc acgagcagcg ccccgcccca ctccgcggcc actccgggca tggggcccag
     2821 caggccggtg aggccctgtt tgacggccaa cgccacgagc ccgcccacca ccgccgcgcc
     2881 gtacaacctg ggcagcaggc ccgacggcag gcccacagga cccaccatgg agcgcagctt
     2941 gcggcgcagg agcgtggtct ccacccaggc cacgacgccg ctggacaggg tgaggaacgc
     3001 cgcccccagc tcccggggca gccccaaccg ctccggcagc cacagcgcca ggaaccaggc
     3061 cttcacggtg cccagggcca cgcgcacgat ggcgtagcgc aggggcgtct tggggtcctt
     3121 cagcgcgtag aaggcggagg cgtagagccg gcccacggtg gacgcgacca ggcccaccgc
     3181 cgcgcccatc agcaggtacc agaggtagcg cgagtccgcc gcgccgaagc ggcccgtctg
     3241 caggagcgcc ccgctcacca ggtcccccag gaagaggagc gcggcggcgg acggcaccac
     3301 ccagaaggcg atgcggcgcg agcccgcgtc gatgcggctt cgcagcttcg cgtgcgcctg
     3361 ggtctccccc tccgccgtgg cgcgcgccat ctccggcagc tccgcggcgg acaccgccat
     3421 gccgaagagg ctcaccggga tgaggtagat ggtctgcgcg tagagcagcg aggacagcgc
     3481 ccggttggag atgagcgacg cgaaggcggt gtccacccac gcgctgaact gcaccacgcc
     3541 gcgccccagc accaccggcc cgaagttctt cagcacctga cgcacggagg cgctggccag
     3601 ggacagcacc gggcggaagt ggcccagcag gcgcatcacc gtgggcacct gcaccgcgaa
     3661 ctggaggaag ctgcccagca ccacgccgta ggccagccac tccgtcacgg cctcttccgc
     3721 ggcgcggccg ccggcgcccc catgcacgct gcccaccgtc agcagcgtgg cgatgatgac
     3781 gacgttccag accacgggcg ccaggtagga cagcaggaag cgccggtggc tgttgaggat
     3841 gcccaggcac cacgcgctca agacgaggaa gcccgtgccg gggaagagga tgcgcaccag
     3901 gcgcaccgcc aggtcgcgct cgccgccttc gaagcccggc gcgatgaggt ccacgaacag
     3961 cggcgtggcc agcatgccca gcgccaccat cacgcccgtg gccagggcca gcagcccgaa
     4021 caccgcgccc gcgacccggt ccgcctcgtc cgtgtccttc ttgcccagca gctgggcgta
     4081 gacggggatg aaggagcccg acagcacgcc ctccccgaag aggttctgga ggaagttggg
     4141 gatgcgcagc gcggccttga agacggcggc ggcctccgcg ttgcccaggt agtgcgcgaa
     4201 gacccgctcg cgcaccaggc ccatcagccg cgacgccagg atgccgatgg ccaccagcat
     4261 ggcgccccgg cctcccgcgc tgcgttcagg gacggacggc ggggggacgg ccggagaggc
     4321 gggctgggac ggtgaagcag gcgcgggggc ggtcacgaag gggcggactc tacgtccggc
     4381 gttcttcggc atgcagcagg aaacccttcg accgctgttt ctcttgacgc tcaccccaca
     4441 ggttgcgagg ttccgcccca atggccggaa agtccgacac cgagcggtcc gacgtcgcga
     4501 gaatccgcgc cgtgctggca cgcgaactcg agacgatcaa cgagtacgag gcgtacgccg
     4561 aggactcctc ccatccggag gtgaaggcct tcttcctcca cctggcggcg gaggagaagg
     4621 agcacgtgtc cgaggccacc cacatgctcc ggatgctcga caagggacag gacgcacact
     4681 tcgccaaacc cttcgtcccg ggccacttcc aggccgccgc ggggggggcc cccgccgcgg
     4741 agcccaccgt ggcccctccg cccgcgccgc caccggcccc gccctcggtg ggccgcctgg
     4801 cgaacgaacc cctgacgtcc ctgccgcccc agcgcctcat ctatggcgtc cccgcgccgc
     4861 cgccttccgc caacggccat cccctcacca tcggcagcct gcgccgcggc ggtggaggcg
     4921 gtggcggttc cggtcgttga caagccttcc gttgcctttc ctcctcccct cctctgccgc
     4981 cgctcgtgac ggagacacag atgcctgact tccttggaca tgccgagaac ccgctgcgcg
     5041 aagaggaatg ggcgcgcctc aacgagacgg tgatccaggt ggcgcgccgt tcactggtgg
     5101 gccgccgcat cctggacatc tacgggccgc tgggcgcggg cgtgcagacc gtggcctacg
     5161 acgagttcca gggcgtgtcc ccgggcgcgg tggacatcgt cggtgagcag gagaccgcca
     5221 tggtcttcac cgacgtccgc aagttcaaga ccatccccat catctacaag gacttcctgc
     5281 tgcactggcg ggacatcgag gcggcgcgca cgcacaacat gccgctggac gtgtccgccg
     5341 ccgccggcgc cgcggcgctg tgcgcccagc aggaggacga gctcatcttc tacggcgatc
     5401 agcgcctggg ctacgagggc ctgatgacgg ccaacggccg cctcaccgcc acgctggggg
     5461 attggacggc gccgggcggc ggcttccaga ccatcgtgga ggccacgcgc aagctcaacg
     5521 aggccggcca cttcgggccc tacgccgtgg tgctgtcgcc gcgcctgtac tcgcagctgc
     5581 accgcatcta cgagaagacg ggcgtgctgg agatccagac catcagccag ctcgcgtccg
     5641 acggtgtcta ccagtccaac cgcctgcgcg gcgagtcggg cgtggtggtg tccacgggcc
     5701 gggagaacat ggacctggcg gtggccatgg acatggtcgc ggcatacctg ggcgccagca
     5761 agatgaacca cccgttccgc gtgctggagt cgctgctgct gcgcatcaag cacccggacg
     5821 ccatctgcac gctggaaggc gccgtcccct ccgcgccccc ggcgcgccgc taggtcgcgt
     5881 tcctcgcgcg gaggcttatg gcgaaggtcc tggtcatcga cgacgagacg aacctgcgca
     5941 aggtgctggc cgccctgctg cgccgcgacg ggttcgacgt caccgtggcg gagaacggcg
     6001 agcagggcct ggccgagttc cacaagaacg gcgcggacat cgtcgtcacc gacctggtga
     6061 tgccgaagct gggcggcatg gaggtgctgt ccgccgtgcg cgccgccaac ccggacgtgc
     6121 cggtgatcat catcaccgcg cacggcaccg tggactccgc cgtggaggcc atcaaggcgg
     6181 gcgcgttcga ctacatcacc aagcccttcg accaggcgga gctgtcctcc gtcgtggcca
     6241 aggccgccaa gacaaacgag agcgccaagc gctccgtgcg cgcggaccac aaggcccgct
     6301 ccgccatcat cggcgagtcg ccgcagatcc aggacgtcta caagatcatc gacaaggtgg
     6361 cggacacgcc gtccacggtg ctgatcacgg gtgagagcgg cacgggcaag gagctcatcg
     6421 ccaccgcgct ccacggcgag tccagccgcc gcgacaagcc gttcatcaag atcaactgcg
     6481 ccgccatccc cgccacgctc ctggagagcg agctgttcgg ctacgagaag ggcgccttca
     6541 ccggcgccgt cacctccaag ccaggccgct tcgagctggc cgacgaaggc accctcttcc
     6601 tggacgagat cggcgagatc cccgtcgaga tgcaggtgaa gctcctgcgt gccctccagg
     6661 agggcgagtt cgagcgcgtg ggcggcatca agacgacgcg ggtgaacgtg cgcctggtgg
     6721 ccgccaccaa ccgcgacctc caggcggaga tcgaagcggg ccgcttccgc aaggacctct
     6781 actaccggct ggcggtggtg cccatcgtgc tgcccgcgct gcgcgagcgc cgcggcgaca
     6841 tcccgatgct cgcccagcac ttcgtggaca agtacaaccg gcgcctccac aagaagatcg
     6901 aaggcatcgc cgacgacgcg ctcgcgctgc tccaggcgta cgcgtggccg ggcaacatcc
     6961 gcgagttgga gaacctcatc gagcgcgtgc tgctcttcgc ggacggcccc ctcatcaccg
     7021 ccagggatct gccggagccg gtgcgcggag gagcgggcgt acaggcgggg gcaccggtcg
     7081 ccgcctcgct gggcacgctg gatgtccccg tgggcgaggt aggcctcaag gacatcgtgc
     7141 gcatgaaggc cgccgagctc gagcgggacc tcatcgtcaa gaagctggag gagacgggcg
     7201 gcaacgtcac gcgcgccgcg cgcctcctgc agatcagccg caagtcgctc cagacgaaga
     7261 tgaaggagtt cggcctgcgc gacaccaccc cggacggtca ggaagacggc ccggacgagt
     7321 agcctggggg ccgaaatatc gcctttttgc cggcggtttc ggcccccgcg taccttctta
     7381 ccctcaggga gcctgaatgc ggccgaatct tcccaccctc ggtggaccac cgaagcgcaa
     7441 tcccttcgga ccggtggttg ccgtctccgt catcctcggc gcggccgcgg gtggcgtgtg
     7501 gtggtggaaa cagcgcatgg cggacgtccc catggacgtc gcctctcaac cggcgtcccc
     7561 gcaggacgcc ggcaccatcg ccgcggcccc cgtggcccca cccgcgccca ccaacgaccc
     7621 cgtgaaggcc gcgggcctgg agcgcgcgtc catccgcatc gagggtccgc tggagaccgc
     7681 cctcatccag gcctccgacg ccaccgtggg gcccgccctg gcccaggtgg tgacgcgcac
     7741 cctggtgtgg tgggtgcgcg tacccggcga aatcctccgg ggagacaccc tggacgtgct
     7801 ctaccagcgc cgccccaacg aggagccgct ggtgtacgcg gtgcgcttcg tgagcggcaa
     7861 gacgggccag acgcaccgcg cctaccgctt cacgcccgcg ggtgagcaga acgcccacta
     7921 ttacctcccc aacggcgacg agctggagct gcggatggag aagtccccca tcgacagcta
     7981 cgagcagatc acctcgctcc tgcgcgacgg ccgtggccac aagggcgtgg acttccgcgc
     8041 cccggtgggc accagcgtcc gggccccctt cgcgggtgtc atcaagcgca agaactggaa
     8101 cttcggcagc aacggcaact gcttcgagct ggtggagtcc ggaggcaagg gccgcagcgc
     8161 cctcttcctg cacctgtcgg agctgcccaa gacgatccag cccgggctgc gcgtgtccgc
     8221 cggccaggtg ctggcccaga gcggcaacac gggccactcc ttcgcccccc acctgcacta
     8281 ccagctcatg tcgggcgatg gccgggtcct ggaccccttc gaccagcaca agacctaccg
     8341 cgcgtcgctc gtggccaccc agaagggcgc cttcgacgcc gaggtccagc ggctggacgg
     8401 cctgctcggc acccccgtcg cggggaagta aagctccacc catttcttga cactcctccg
     8461 acggcacggc tagctggcag gcctgggccg tggtcgtcgg aggtagtgga tgcacaggtt
     8521 tcgcgccgtc atcgccgcgc tgacgctggg cgtgccgttc gccgccagcg cggcggagat
     8581 cacccggatc gcttccgcct tcgaggagga tgatccgttc gatctcttcc tcgacgtggg
     8641 cttcgagcgc acgcagacgc gagcgaagat cgtccgcgag cagctcaccg gcggcgacgt
     8701 caccaacgtc ccggaggtga acgagctctg gtacaagggc gtggacgcgc ggctgaacct
     8761 ggccgtggcc ttcggcctgt ggaaggacct ggagttcagc ttcaagctgc ccatcgtctt
     8821 ccagcagaac gagacctgga acttcgtgtc cggcacgaac cagcgcaact ccaccatcac
     8881 caacagctgc ttcaacgcgg acggctcgcc ctactcctcc gagggctgcg tgggccggct
     8941 gttccaggtg ccccaggaga gctaccgcgg cggcctgggc aacgtgcact tcgggctggc
     9001 gtatgccttc ttcaaccaga agaaggacga caccaagccc acgtggatcg tcggcatcga
     9061 ctacgaggcg cccaccgcca agcagcgcga cccgagcctg gacaacaccg acccggacgg
     9121 cgaccgcggc aacgtgggcg accgcgtgca caagtaccag ctctacacga ccttctcgcg
     9181 caagatgggc gtggcggagc cgtacttcaa ggcgtcccac accatcccgg tgcggggccc
     9241 cggcgcatac tcgaactgcg accagtccgg cgccaacccg cccaacctgg gggcgccggg
     9301 caactgctac aaggagccgt ggacccgcaa cgagacgggc attcacgccc cctcgcagac
     9361 ggcgctcacc ttcggcatgg agctggtgcc cttcgagaac gcgacgaagt cccagaagct
     9421 catcctggac ctgcgcatgt tgggcaacta cgtgggccgc ggccggtact acaacgagct
     9481 gacctccgcg ctgcgcaagc tgctcacctc ggacgactac ttccaggtgg gtggacaggt
     9541 gggcatcacc gcccgcgccg cgcaggcctt caccatccac gcctccggca agttcctcta
     9601 caacacggac cacctgctca cgaccgaggc cattggccag gacctgaacg gcgacggcac
     9661 cgtggacacc gccgtgggct cgccggagct gaaccccacg ttcgactggc gctacgacct
     9721 ggtgtcccgg cgtttccggg ccatccagag caccacgttc cgcttcgacc tgggcgcgac
     9781 cttcaacttc tgaaggcccg cccctgacga cgacgcggca gcggcggggc tcccctaccg
     9841 ctgcttcagc cccaggccca gccggtacac ctcctggccg ggccaccccg cgcgccgggc
     9901 cagctccgtg ctcagcggct tgagcttctc cccgcgagcc aggcccgact ccagcgcccg
     9961 gcgcacctcg tcctcgctcc agcgctgctc gccggtgcgg ccctccacca gcaccaccac
    10021 ctcgccccgg gtctcctcgg ccgcgtagcg cgccacgagc gtggacagcg ggccccggac
    10081 gaactcctcg tgcagcttgg tcagctcgcg cgccacgcac gcgcggcggt cgccccaggc
    10141 ctcctggagg tccaccagcg tctccgccag gcggcgcggg gattcgtaga ggacgcaggt
    10201 ggcggacagg ggggccacct cgtccagcat ggcgcggcgc tccggcccct tgcgcggcag
    10261 gaagcccagg aagtggaagc gcccggtggg cagccccgac gcgctcagcg cggccaccag
    10321 cgccgtgggc ccgggcaccg gctccacctt caggccgcgc tccagcgcct ccgccaccag
    10381 cttctccccg gggtcgctga tgccggggct gcccgcgtcg gtgacgagcg cgcagtcctc
    10441 ccccgcctcg atgcggtcca ggatgcgccc ggcgcgctgc ccctccgcga aggcaggcag
    10501 gctcaccagg tccttcccgg tgatgccgaa gtggtccagc aggatgcgcg agtgccgggt
    10561 gtcctcgcac gcgaggaagc ccacggtgcg cagcgtctcc agggcccggg cggtgacatc
    10621 ccccaggttc ccgatgggcg tggccacgag gtagagcgtt ccagccaagg gacggattcc
    10681 tttacatgcc agcgtcgaag gcggcgggca ggtgctccac ccgggcgtgt tcgccctgcc
    10741 ccacgacgga gatgacgtcg aagcgcacca tgcgcccgtc gatgccgttc tggaagagat
    10801 agtgcagcgc ggccttcacc acccggcgct gcttggcgaa ggacacggtg tgcgacgggt
    10861 caccccaggc cgc
//
