LOCUS       NZ_JAIHBQ010000001     20945 bp    DNA     linear   CON 08-NOV-2024
DEFINITION  Streptomyces lateritius strain Z1-26 tig00001, whole genome shotgun
            sequence.
ACCESSION   NZ_JAIHBQ010000001
VERSION     NZ_JAIHBQ010000001.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces lateritius
  ORGANISM  Streptomyces lateritius
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Kitasatosporales; Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 7761152)
  AUTHORS   Yang,Y. and Zhai,F.
  TITLE     The genome of Streptomyces lateritius
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 7761152)
  AUTHORS   Yang,Y. and Zhai,F.
  TITLE     Direct Submission
  JOURNAL   Submitted (17-AUG-2021) Life and Science College, Hunan Normal
            University, Juzizhou Street, Changsha, Hunan 410018, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Flye v. 2.5
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 235.0x
            Sequencing Technology             :: Illumina NovaSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_019733325.1-RS_2024_11_06
            Annotation Date                   :: 11/06/2024 09:08:10
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,226
            CDSs (total)                      :: 7,130
            Genes (coding)                    :: 6,956
            CDSs (with protein)               :: 6,956
            Genes (RNA)                       :: 96
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 175
            CDSs (without protein)            :: 174
            Pseudo Genes (ambiguous residues) :: 0 of 175
            Pseudo Genes (frameshifted)       :: 57 of 175
            Pseudo Genes (incomplete)         :: 135 of 175
            Pseudo Genes (internal stop)      :: 9 of 175
            Pseudo Genes (multiple problems)  :: 27 of 175
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 17:31:25
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 7532494
            Orig. end                         :: 7553439
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JAIHBQ010000001.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..20945
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="29"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..20945
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20945
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:10945](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10945
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            394..567
                     /locus_tag="K4902_RS34100"
                     /old_locus_tag="K4902_34100"
     CDS             394..567
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010982395.1"
                     /locus_tag="K4902_RS34100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K4902_34100"
                     /product="hypothetical protein"
                     /protein_id="WP_198942299.1"
                     /transl_table=11
                     /translation="MSAKEKTKATTEQVVGKVVRKVAHAMGKDTTAAKGAALEARGKAR
                     ATKESAKGGFRH"
     misc_feature    complement(407..421)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.13"
                     /tool="antismash"
     misc_feature    complement(862..871)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 15.37"
                     /tool="antismash"
     gene            928..1770
                     /locus_tag="K4902_RS34105"
                     /old_locus_tag="K4902_34105"
     CDS             928..1770
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015578354.1"
                     /locus_tag="K4902_RS34105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K4902_34105"
                     /product="hypothetical protein"
                     /protein_id="WP_073815209.1"
                     /transl_table=11
                     /translation="MGQPEQRAEGAGPFTTRLTWKRPAGETVVWDSRLARRRGAMSVRG
                     QGDAVSTYAVADAEALGRLRRLNAVASAAFVIGGALFALGAAVSQFGSGGAAESASIYF
                     AGGLFFNLGGYTSLLQVMNAPRHSQEGGPLVTAGWRWWAYEPMRLDWLSTFVLFVGTLV
                     FAVNLLDSFLQGLTVQQINRLIWTPDVIGCVLFLVSGHLAFAEICHRRWPCVRSRSLGW
                     WVVAVNQFGSVLFMISALAAFTRPDTGSLINTDIANWGTLTGALCFSLGGVLQFFERP"
     tRNA            2153..2271
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="K4902_RS34110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="K4902_34110"
                     /product="tRNA-OTHER"
     gene            2153..2271
                     /locus_tag="K4902_RS34110"
                     /old_locus_tag="K4902_34110"
     gene            complement(2432..3229)
                     /locus_tag="K4902_RS34115"
                     /old_locus_tag="K4902_34115"
     CDS             complement(2432..3229)
                     /EC_number="3.1.-.-"
                     /GO_function="GO:0016788 - hydrolase activity, acting on
                     ester bonds [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020132742.1"
                     /locus_tag="K4902_RS34115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K4902_34115"
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="WP_221747397.1"
                     /transl_table=11
                     /translation="MRNGQYLRYVALGDSQTEGVGDGDDTIGLRGFADRLAERISVVSP
                     EVRYANLAVRGRLAGQVRAEQLGPALALRPDVATVIAGVNDLLRPRFDPDETAAHVEAM
                     FAALTAAGARVATVTIPDITRIAPIARPVAPRIAALNDRIRLAAARHDVALAETSPHAA
                     ATDPRFWATDRLHASPLGHDRISAALAHALGLPGSDDSWTQALAPSSSTTVGAMRTAAT
                     ELRWAAGFLGPWLLRRLRGQSSGDGRAARRPELLPVGVPPVGI"
     misc_feature    3230..3244
                     /note="TFBS match to OsdR, Development and stress
                     management regulator, confidence: weak, score: 24.03"
                     /tool="antismash"
     misc_feature    complement(3283..3298)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 18.19"
                     /tool="antismash"
     misc_feature    3671..3686
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 18.33"
                     /tool="antismash"
     gene            3807..4133
                     /locus_tag="K4902_RS34120"
                     /old_locus_tag="K4902_34120"
     CDS             3807..4133
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018565362.1"
                     /locus_tag="K4902_RS34120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K4902_34120"
                     /product="WhiB family transcriptional regulator"
                     /protein_id="WP_073815203.1"
                     /transl_table=11
                     /translation="MAGHDQETWSARALCRTADPDELFVDGAAQNQAKALCTGCPVRTE
                     CLAHALDQRIDHGVWGGMTDRERRALLRRRPTVTSWRRLLDAARMEYERQPHDGNRSLR
                     QAVS"
     misc_feature    complement(4446..4461)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.29"
                     /tool="antismash"
     gene            4552..4995
                     /gene="mscL"
                     /locus_tag="K4902_RS34125"
                     /old_locus_tag="K4902_34125"
     CDS             4552..4995
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0008381 - mechanosensitive monoatomic ion
                     channel activity [Evidence IEA]"
                     /GO_process="GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /gene="mscL"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020124849.1"
                     /locus_tag="K4902_RS34125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K4902_34125"
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="WP_073815199.1"
                     /transl_table=11
                     /translation="MKGFRSFILRGNVVDLAVGIVIGAAFTAVVNGFVGAFLTPLVGLA
                     TGVTGDMSRKSFTLGGTQFPYGAFVNAAISFLLLASALYFLVVLPINKLHERLAPHHDV
                     QAPKRDCPECLSPVPAQARRCASCTAPLPAVPAQAGETTQRAG"
     misc_feature    5146..5161
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 17.89"
                     /tool="antismash"
     misc_feature    5421..5431
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.59"
                     /tool="antismash"
     gene            5512..5820
                     /locus_tag="K4902_RS34130"
                     /old_locus_tag="K4902_34130"
     CDS             5512..5820
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018523379.1"
                     /locus_tag="K4902_RS34130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K4902_34130"
                     /product="hypothetical protein"
                     /protein_id="WP_073815194.1"
                     /transl_table=11
                     /translation="MTTFVITVPGTFTSDITESERVALERKLAPQHTDVSESEGVNLLT
                     LNEDGTFAIRLEVDAADRYEAKLDATKLVSTALKEAGIAEADAPLGQPAVTGIDSDL"
     misc_feature    complement(5850..5867)
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 20.89"
                     /tool="antismash"
     gene            5911..6084
                     /locus_tag="K4902_RS34135"
                     /old_locus_tag="K4902_34135"
     CDS             5911..6084
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013006105.1"
                     /locus_tag="K4902_RS34135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K4902_34135"
                     /product="hypothetical protein"
                     /protein_id="WP_198942298.1"
                     /transl_table=11
                     /translation="MLGIAAAVLFFIAFLINAADISTNEAFSSTNLMLLGLTALALQVA
                     GIGAGRSGRRRS"
     gene            complement(7020..7703)
                     /locus_tag="K4902_RS34140"
                     /old_locus_tag="K4902_34140"
     CDS             complement(7020..7703)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1116:
                     Homoserine/threonine efflux protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010981681.1"
                     /locus_tag="K4902_RS34140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K4902_34140"
                     /product="LysE family translocator"
                     /protein_id="WP_221747398.1"
                     /transl_table=11
                     /translation="MSVDLVGFLGVVLVAYVVPGPDFLVVVRAAAEAPSKGRAAALGAQ
                     AGLCVHMFAAAIGLAVVASRYPVVYDTVKLLGAAYLIYLGVRAVRAARRAVQEQRPGDA
                     AASGGPDVGDCPARRPAVEGKAAARRWRSGFTEGLLTNVLNPKAALFFLSVLPQFVDSN
                     GSLWRQILFLGILDVLIGVAYWFVLVLIAARLRALLARPKVRYRWELTTGCLFIAIGVG
                     LATAA"
     misc_feature    complement(7948..7963)
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 20.27"
                     /tool="antismash"
     gene            8089..8778
                     /locus_tag="K4902_RS34145"
                     /old_locus_tag="K4902_34145"
     CDS             8089..8778
                     /NRPS_PKS="Domain: Abhydrolase_1 (39-145). E-value: 4e-11.
                     Score: 34.9. Matches aSDomain:
                     nrpspksdomains_K4902_RS34145_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020122370.1"
                     /locus_tag="K4902_RS34145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K4902_34145"
                     /product="triacylglycerol lipase"
                     /protein_id="WP_221747399.1"
                     /sec_met_domain="PF00561 (E-value: 1.4e-07, bitscore: 30.1,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRNLSRSLCTLLLALVALSPVPASAADGRRGAEAVRPDPVVFVH
                     GWNSDGSTWRTMAGRFQADSWPLDHLDQWTYDATQSNATTAARLAEEIDRVLARTGAAK
                     VDIVTHSMGGLSSRYYLKNLGGTSKVDAWVSLAGPNHGTGAARLCGGDPCVEMRPGSLF
                     LNALNSGDETPGSPRYATWRSPCDLVISPGDSVALAGAVNSTTGCLGHSELQADAAVYE
                     QVKQHIS"
     aSDomain        8206..8523
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_K4902_RS34145_Abhydrolase_1.1"
                     /evalue="4.00E-11"
                     /label="K4902_RS34145_Abhydrolase_1.1"
                     /locus_tag="K4902_RS34145"
                     /protein_end="145"
                     /protein_start="39"
                     /score="34.9"
                     /tool="antismash"
                     /translation="PVVFVHGWNSDGSTWRTMAGRFQADSWPLDHLDQWTYDATQSNAT
                     TAARLAEEIDRVLARTGAAKVDIVTHSMGGLSSRYYLKNLGGTSKVDAWVSLAGPNHGT
                     GA"
     gene            complement(9239..9772)
                     /locus_tag="K4902_RS34150"
                     /old_locus_tag="K4902_34150"
     CDS             complement(9239..9772)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="K4902_RS34150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="K4902_34150"
                     /product="hypothetical protein"
                     /protein_id="WP_221747400.1"
                     /transl_table=11
                     /translation="MDEASDAVGQALCCAAAVRLGGAVQVLTERDGLLDHYIPIMAGVE
                     SISAFLNGHELDDGLLGAAFAGSWYLDARYQTGLPGYALVKDWTSLVFGTAVLTRPEQQ
                     SILAEQTLDFASKAAAAWPSAVRVSSFDSLARFELACQQEAEDRLRKDGLPALWKLTEV
                     RSKPYRQVAEQLIG"
     gene            10001..10945
                     /locus_tag="K4902_RS34155"
                     /old_locus_tag="K4902_34155"
     CDS             10001..10945
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012705.5"
                     /locus_tag="K4902_RS34155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K4902_34155"
                     /product="squalene/phytoene synthase family protein"
                     /protein_id="WP_073815180.1"
                     /sec_met_domain="phytoene_synt (E-value: 2.1e-17, bitscore:
                     61.9, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 5.1e-12,
                     bitscore: 44.3, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MWKRALDRAGVNERRLRRDYTEQRRQVRRYRTAEYAAARLLLPAA
                     LLPHVVAAVAFMHDTDDRIDRGAPQERAAALAEWDALVRKALAEGDSELPALRCLVHTA
                     AQHPDVRAYVDEFLQGCEREVAWRSIADDEELEEYVREYCLPALMLTACLLAPADASER
                     AAFVDGCHRLIRAMQRIDFLEDLPEDVRAGRPGIPADAVARHGADLSRPGAGLGRLVEE
                     QADRAATDLAAAGPLADVVDLAYRPFLRALVGVQHLRLNAVRRAGASLATRSSGPPAPA
                     AAALLLRETAARARQAVRLGSDASRPYSKPANT"
     misc_feature    10046..10048
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(11285..12694)
                     /locus_tag="K4902_RS34160"
                     /old_locus_tag="K4902_34160"
     CDS             complement(11285..12694)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="K4902_RS34160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="K4902_34160"
                     /product="hypothetical protein"
                     /protein_id="WP_221747401.1"
                     /transl_table=11
                     /translation="MTPNQRMTNRFHLSCLATLIPYHQRPAALEAWLDIDPTLFFMGFD
                     PPAPVVEAVLRLGGTRLRAALAHTVGNEGTQRALFDLDVPEVGAALLGNHRLGYATLCL
                     LRVRDPIAAATSRSYHQGHHRRALFSSDAALAAAALLDLRGEHPPTARATAWETVRAAG
                     GTARVRELAGLLPGRGGPTDADADVVAACAEADPEPFLDCAAERRLGTGALLRRLRAAH
                     RPDSPPWKVQQVMRSILEEPYRIDWRLVAAARLGHRLPRTAAEVLRSRPECPPEVAVVL
                     RTGRPAVPGRPLPPPAREAEVRQPPRRPDSHWVPPWQPPGDTGPFGDTAASARQALRTM
                     TVVYDAHRDPEAPHLGHLSAVLERGQLSAAEAVPLMRPASLLTSWVGQHSGWADVSRAA
                     WSGRAALHVETAALLARWSNGGVPAEWWAALLPRLWHFPGTLPELLAEVSGSRSDGREE
                     SGPEDFDEPER"
     gene            complement(12864..13220)
                     /locus_tag="K4902_RS34165"
                     /old_locus_tag="K4902_34165"
     CDS             complement(12864..13220)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020129609.1"
                     /locus_tag="K4902_RS34165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K4902_34165"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_073815174.1"
                     /transl_table=11
                     /translation="MVGVPESHNGWTFVTNHARVLAVIADNPNVRIRDIAAHCRLTERA
                     VQRIISDLEQDGYLSHTRDGRSNTYRIEPGKVLRHPAEAGLPVASLLSLLVQDETHRAQ
                     KAQAQSPRLADTTA"
     misc_feature    complement(13233..13247)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.31"
                     /tool="antismash"
     gene            13403..13750
                     /locus_tag="K4902_RS34170"
                     /old_locus_tag="K4902_34170"
     CDS             13403..13750
                     /GO_function="GO:0043856 - anti-sigma factor antagonist
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018104915.1"
                     /locus_tag="K4902_RS34170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K4902_34170"
                     /product="STAS domain-containing protein"
                     /protein_id="WP_241845599.1"
                     /transl_table=11
                     /translation="MSVLERAAVTQYERHGACVVVPRGSYDMESIDPLAAVLAAASAEH
                     RPIVLDASGITFADSALLNLLILTRKEADLRLAAPTPQLQRILEITGVDTILKVRTTVE
                     DAAACPADGRC"
     gene            complement(14252..15106)
                     /locus_tag="K4902_RS34175"
                     /old_locus_tag="K4902_34175"
     CDS             complement(14252..15106)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="K4902_RS34175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="K4902_34175"
                     /product="hypothetical protein"
                     /protein_id="WP_221747402.1"
                     /transl_table=11
                     /translation="MANEPVNTSIQNKYAEQLASDLASNQAEQATLTVRLSQLQEEEKW
                     LTKTLESLPTAVEGETAADVESVGSTAPVAAGTEAAAVPQPRAEKTGGTASVRKSPAKK
                     ATAAKRATAKAPASKKAPAAKKASAAKGVPAAKEAPAEKAPTVEKAAVEETQGAKKAAS
                     GKAPAAKKTAVKKATAASAKKTVKSVGPTLGELLKELLAQQPGEPKKVSEIGSELKAAH
                     PERTTSDQVVRNTLERLVVKDGLEKDTRQGVVLYTWPTPEAHAPAAAQVRDGEPAEAAT
                     AGV"
     misc_feature    complement(15069..15082)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: medium, score: 21.28"
                     /tool="antismash"
     gene            15436..15759
                     /locus_tag="K4902_RS34180"
                     /old_locus_tag="K4902_34180"
     CDS             15436..15759
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006140716.1"
                     /locus_tag="K4902_RS34180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K4902_34180"
                     /product="VOC family protein"
                     /protein_id="WP_241845596.1"
                     /transl_table=11
                     /translation="MKCGFETSAEWGPVQLSNGVTLDFAAVPPETITPQHYAFLVSEEE
                     FEAAYARILHRGIEHYADPHRKQPDAINHHDGGRGVYFVDPVGHLLELITVPYGGWTSS
                     PHT"
     misc_feature    complement(15879..15892)
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: weak, score: 18.12"
                     /tool="antismash"
     gene            16029..17813
                     /locus_tag="K4902_RS34185"
                     /old_locus_tag="K4902_34185"
     CDS             16029..17813
                     /GO_function="GO:0008253 - 5'-nucleotidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1283: 2`,3`-cyclic-nucleotide 2`-phosphodiesterase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020548877.1"
                     /locus_tag="K4902_RS34185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K4902_34185"
                     /product="bifunctional UDP-sugar hydrolase/5'-nucleotidase"
                     /protein_id="WP_221747403.1"
                     /transl_table=11
                     /translation="MRNFLRRIGVIATGTALLGGALSVSPAAADDIVDVQLLSITDFHG
                     YLQPPTAGQGGSIPTGRGTSVTVGGAAYIATHLQRLRGDHPRSVTFATGDSFAGWPFEV
                     DAFQDEPTIEVLNKLGVRFSAMGNHELDVSADFLVQHMEEGRCFGKVDVDSCFTDSTGR
                     RFHGADFDFQSGNIVDARTGRPVVDPYRIEWFRSAGGKRIPVGFISTTVEGSVTNSTSF
                     QPQLRALDQARTIQRYTKELKRRGVEAIVLNVHEGGSPTDPATAGYNACDSVFGPVFEL
                     AKKVPAEIDAIVTGDWHWRFNCMVPDPAGVPRPIVEAGNHGAVINEINLSLDPRTGDVL
                     RDRTRSVNHAVTRDVAPDSAVQKIVDYWVARGARRFAEPLARQTGSFTRTPNAAGESTA
                     ADLYADVQYWNANRTRAGQADLALISARPAKGSNAVRGDLPFGKGSHPADADGRILFGE
                     SWNAYGYGNPVLTVGVRGRQLDAILEQQWQKQADGSVKFAPLAVSRNVSYSYDAARPVG
                     DRVSPRDVVINGRPLDPARTYRVAALAYTVVGADGYGAFAGYTEPVRNGADHESFVEYL
                     KTHKTISPAPLNRIRVKS"
     gene            complement(17938..19446)
                     /locus_tag="K4902_RS34190"
                     /old_locus_tag="K4902_34190"
     CDS             complement(17938..19446)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010474465.1"
                     /locus_tag="K4902_RS34190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K4902_34190"
                     /product="DUF4246 domain-containing protein"
                     /protein_id="WP_221747404.1"
                     /transl_table=11
                     /translation="MTGLSAFPLPFRASRSLSFATPRTLRELQMMQCSAHIRAKPEWFE
                     KMHDADIVARWTREALAQGLTEAQVRHVLAELVHYAGLRDGGTGVEVSAVDGVWQSDTL
                     VDDKLRSRLREAVRVLEQVPEAERDWHPGSDGQVLDLVHPSLFCLVRGVSGAPDRAWQN
                     PADRYSKYEFSERFQWLPTDVDVNDDGDVAFRSYINNVHPEIHHELASVLPDVFARFRP
                     LLENVLTDLRHPRPLRIEADPYGWYDSEPEYPDRSSYSEDGAYAEAVRAWEMAQDDWWE
                     NRRPVVPDAPAFTAPELPDESARVDLRGRRLQVIVKLATIHLTPDKPEYPGGSWHVEGM
                     MNERIVSTGIYYWDSENITESRLSFRTALDDPSYEQNDDNGLREVYGLEDEDALNQVLG
                     AASTPAGRCLAFPNILQHRVGPFSLADPARPGHRKILAFFLVDPSETIVSTSEVPPQQP
                     WSESSTMTLDEAKDYREQLMQERKFFVDEHNEQLYERAFSLCEH"
     gene            complement(19628..20833)
                     /locus_tag="K4902_RS34195"
                     /old_locus_tag="K4902_34195"
     CDS             complement(19628..20833)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019891468.1"
                     /locus_tag="K4902_RS34195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K4902_34195"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_221747405.1"
                     /transl_table=11
                     /translation="MNKLTHAAAAVLLACAVALPATTATAVAAPASSYAPATTPDRSAD
                     GVRLPAPTGPHRVGSSVLYLVDRSRTDPWVPEADGREIMVTLHYPAARSSAAGHTPGRP
                     APYATQEEARLLLQGVPVEDPASVRQVARARTHSAVNVRPAPGRHPLVVLSPGFGMPRF
                     TLTSLAVDLASRGYVVASLDHAYESSGTSVPGGRTLTCVACTAMEESGWSKGHLVTGAR
                     AADTRFVLDRLTGPRSAWRYASSIDRTRIGMAGHSIGGASAVSAMAADRRIDAGVNMDG
                     SFWDTLPADGLGGRPFLLLGTDESHRPGGEDTSWDTTWTALGGEKHWLTVDGADHLGFS
                     DAPVLLGHFGLPGGDLPAERAVALTRTYVAAFFDEHLRGKDQPLLDGPDETYPEVRFHR
                     PE"
     misc_feature    complement(20777..20779)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
ORIGIN
        1 tcgaggcggt gaaggccgtc gtgacggcca acggcggcac tctccccgac aacgcccggg
       61 cgaagctgcc gcaggccgtc gccgggctgg ccttcgacgg tgtcaccggc cgcgtcgcct
      121 tcaacgagaa cggcgacacg gtccaccgcc gactgacggt gtacgaggtg aacgccggca
      181 actggaagcc cgtgacgagc ggccccgcca ccccctgaca cctggccgcg gaagcccggc
      241 gggcgtctcg ccgcgtggcg ggcggcgcgc cgcccccacc ggatcgatcc gccgccgccg
      301 gacccaccgc gccctggcgt gctcaccttc cggactggtt tccccttgcg gcgcacgggc
      361 aggcgcacga caggcgtcga tgaagggacc gtcatgagtg ccaaggagaa gacgaaggcc
      421 acgaccgagc aggtcgtcgg aaaggtggtg cgaaaggtgg cccatgcgat ggggaaggac
      481 accacggccg ccaagggcgc ggcactggag gcgcggggca aggcccgagc gacaaaggag
      541 agcgcgaagg gcggcttccg ccactgatcg cgtcgcctgc actggtcccg cacctgctgc
      601 gatggctggc cgagagcagc gaggagcgtg tgtacgacgc ccgcggtggc gcgggacctc
      661 gtcgtcgaat ccggcgcacg gacggcggcc cggatggact gcaggagccg gctgctgccg
      721 tacggctgcc gggtctgacg gcgaagctgc gggcgaccag gaacgggcga ggcactgtct
      781 ccatccgaac acagtgagcc gaccagaacc agcaaccgag ggagcccgcg ctacgcccgc
      841 ccgccgaggg aaccgaggcg atcaaaaagt aagaacaggt acgtttcgct gttcgtcgat
      901 catcacacgc gggactaggc tcggcccgtg ggacagcctg agcagcgcgc cgaaggtgca
      961 ggaccgttca ccacccggct cacgtggaag cgccctgcag gggaaacggt ggtgtgggat
     1021 tcgcggctcg cgcgcaggcg gggagcgatg tcggtccgcg gtcagggtga cgcggtcagc
     1081 acgtacgccg tggccgacgc ggaggccctc ggccgccttc gaagactcaa tgccgtggcc
     1141 tcggctgcgt tcgtcatcgg cggagcgctg ttcgctctcg gggcggccgt ctcccagttc
     1201 ggctcgggcg gcgccgccga gagcgcctcg atctatttcg cggggggcct gttcttcaac
     1261 ctcgggggct acacctcgct cctccaggtg atgaacgcgc ctcgccactc ccaagagggc
     1321 ggtccgctgg tgacggccgg ctggcggtgg tgggcgtacg agccgatgcg tctggactgg
     1381 ctgagcacgt tcgtcctgtt cgtcgggact ctcgtgttcg ccgtcaatct gctggactcc
     1441 ttcctgcagg ggctcaccgt ccagcagatc aaccggctga tctggactcc cgatgtgatc
     1501 ggatgcgtgc tgttcctggt ctccgggcat ctcgcgttcg ccgagatctg ccatcggcgc
     1561 tggccctgcg tccgctcgcg cagcctcggc tggtgggtcg tcgccgtgaa tcagttcggc
     1621 tcggtgctct tcatgatctc ggccctcgcc gcgttcaccc gcccggacac gggaagcctc
     1681 atcaacaccg acatcgccaa ctggggaacg ctgacgggcg cgctgtgctt ctcgctcggg
     1741 ggcgtcctcc aattcttcga gcgcccctga ggggtgcggt cgccgtcggc acggcgcccg
     1801 ggaagtgctg gccgggatcg cgttcgtgac cacgtccaga cgcacgtgac agctgctgtc
     1861 ttacgcgtcg tgtcttcgac gaactcggcg ctcaccacga gctgaactgg tcccgctgcg
     1921 cgatcgaccc ggtgaacatg ctgacagtga agagggggct gacggttccg aatcagacgg
     1981 accgggtgca cggccgagcg gtcactgctc ggcggggagt cagatcacgg tcctcgcacg
     2041 actgttgtgg ccccacgaca gccttcacca cgtcacagaa atggactcgt gcacggcgaa
     2101 cgatttctct atcttgggcc gcagcgggac tgcgcgtggt cccgcaggtt gcgtgccgtg
     2161 gcagagtggt ctattgcgat cgccgtgggg gaggccccct ccacggcgag tgacggagac
     2221 ggggtggccc tgcccctgtc tgtctcgcgg gttcgaatcc cgtcggcatc gcagccgctc
     2281 cgaggtgtgg ccgagcgcgg aggaatcacc ccgccggaaa gagaacaccc gcgtcgtccg
     2341 gctgcgcgct cagcggctag tgctacgcct cgttcttacc cgccaccgcg agtgcggcga
     2401 gctctctcgg cgctttttcg ctctcagatg ttcatatgcc gaccggcggc accccgacag
     2461 gcaacagctc cgggcgtcgg gcggcgcggc cgtcgccgga ggactggccg cgaaggcgtc
     2521 gcagcagcca ggggccgagg aacccggcgg cccagcgcag ttcggtcgca gccgtgcgca
     2581 tcgcgccgac ggtcgtggac gaggagggcg ccagcgcctg ggtccacgag tcgtcgctgc
     2641 ccggcaggcc gagcgcgtgc gcgagcgcgg cggagatccg gtcgtgaccc agcgggctcg
     2701 cgtgcagtcg gtccgtggcc cagaagcgtg gatcagtggc agcggcatgc ggggaggtct
     2761 ctgccagagc gacgtcgtgc cgcgccgccg ccagccggat gcggtcgttg agggcggcga
     2821 tccgaggtgc cacgggtcgg gctatgggcg cgattcgggt gatgtccggg atcgtgacgg
     2881 tcgcgacgcg tgcccccgcg gcggtgagcg cggcgaacat cgcctccacg tgggcggcgg
     2941 tctcgtccgg gtcgaaccgg ggcctcagca ggtcgttgac tccggcgatc acggtggcta
     3001 cgtcgggccg gagagcgagc gcggggccga gctgctccgc gcgaacctgt ccggcgagcc
     3061 ggccccggac ggccaggttg gcgtaacgga cctcagggct caccaccgag atccgttcgg
     3121 cgagtcggtc cgcgaaacca cgtagcccga tggtgtcgtc gccgtcgccg accccctccg
     3181 tctggctgtc gcccagcgcg acgtaacgca ggtactgacc gttcctcatg ggccgtccgt
     3241 ctctccctgg cactcctgta ccgcatccga aagtacatgg tactcaaaaa aatgagtaat
     3301 cgttctgatg ggtatctggg gtgggggccc cgccgtgctg acgtgtcagc ggtgccctgc
     3361 ggcgggtctg ggtgtccccc tgccggaggt ggcggcacct gcccgatgcg tgttgcgcgg
     3421 gcacggcgta ctcaccttcc gcgtagccga ccctggcgaa ccgaccgacc tcgggcgccg
     3481 gattggcggc ggcacccccg ggctcagcct cctcgccggt acgcgggccg gcgtcggcgg
     3541 tgagcagccc cgccccagcc ccgacgactg ccgacccggt cactcccgcg cttctcgtct
     3601 cggttcgcct gcttcgaact ccggatcccg ggcaaaggaa cgagcgtcgg cggagcgcgg
     3661 caccctggcc gtcacgtctc cttcactcga aagagctacg gaagcgtgga cacgaaccag
     3721 gcagcgcgcg tccccgccgt accgtgtgcg aactgtgccc gcccagggga gtgcggcggg
     3781 ccgaacaggg gagaggacga cgccgggtgg ctggacacga tcaggagaca tggagcgcgc
     3841 gagcgctgtg ccggaccgct gaccccgacg aactcttcgt ggacggagcc gcccagaacc
     3901 aggccaaggc gctctgcacc ggctgccccg tccgcaccga atgcctggct cacgccctcg
     3961 atcagcgcat cgaccacggc gtgtggggcg gaatgacgga cagggaacgg cgtgccctgc
     4021 tgcgccgacg gcccaccgtt acgtcgtggc ggcgcctgct ggacgcggcg cgcatggaat
     4081 acgagaggca gccgcacgac ggcaaccgat cgctccgaca agccgtcagc tgacactggc
     4141 ggaagcgttc gtgggctcga agaccatcgc cacgcgaaag agcccgaccc gacccgacca
     4201 ggagcggggc gatgcgtggg cttcatgcgc ggggtgctga gccgtctgca gcatcggtgt
     4261 cgtacggccc gtagccaccc gccgacggcc ctcgccacca ccggtgccgg agccctcgta
     4321 cgcctggctg atcagctcat acgacaccgg ctccctcagc gcgccgcagc cgaactccca
     4381 agccgggtga tcagccttgg cgcgcccccg catcagcatg ccgacaggcc aagccacgga
     4441 ttgcgtcgca cgggcattgg tcgggagtgg cggggcaacc ggaaaggggg gcggcttcac
     4501 cgcgcccgcg ggatccgccc gtcgacatcg aagaggctga ggagtgagaa ggtgaagggc
     4561 ttccgcagct tcatcctgcg aggcaacgtg gtcgacctgg ccgtcggtat cgtcatcggg
     4621 gccgcgttca ccgccgtcgt gaacggtttc gtcggcgcct ttctgacccc actggtcggg
     4681 ctggccaccg gtgtcaccgg agacatgagt cgcaagagct tcaccctggg cggcacccaa
     4741 ttcccctacg gcgctttcgt caacgctgcg atcagtttcc tcctcctcgc cagcgccctg
     4801 tacttcctgg tcgtcctgcc gatcaacaag ctgcacgagc gcctcgcccc gcaccacgac
     4861 gtccaggcgc ccaaacggga ctgccccgaa tgcctcagcc cggtccccgc gcaggcccgc
     4921 cggtgcgcct cctgcaccgc ccccctgccc gccgtacccg cccaagcggg ggagacgacc
     4981 cagcgcgccg ggtgaccggt ctgcagaccc gtgcttggaa gcgcggaccg tgcagcggct
     5041 cccgacaatc cgctgattgg tctcgcgaat cggggtacac ggcgggcatg ccatcgaaga
     5101 ccgaaagcct catgtccttg cgggccgtac ggcagctgag ccgggttcgc gtcttctaca
     5161 cggccggcgc cctgctgtgg gcggcagccg cgacgtggac gggatggacg catcccggga
     5221 gtcggcagat gtgggtttcc cttctcctca tggcggtctt cgccggcctc ctcgccacgg
     5281 cgtccgtctg gctacggcgt ctcaaggcca ccccggcccg gaggcccgca catcacgccg
     5341 ccccgcgacg cgtagccgct ccacgtcacg cgagcgcctg aatcccggac ctccacgcgc
     5401 cagggctcgt cgcggtccga tgccatgtca gaaaccctct aggcggggtt catcacggag
     5461 gatgagggaa gcagaacgac gctcacactc cgttccatgc gaggagtcgc catgaccacc
     5521 ttcgtcatca ccgttcccgg cacattcacc tcggacatca ccgagtccga gcgggtcgct
     5581 ctcgaacgga agctggcccc ccagcacaca gacgtgagcg agagcgaagg cgtgaacctc
     5641 ctcacgctga acgaggacgg cactttcgcc atcaggctcg aggtcgacgc cgccgaccga
     5701 tacgaggcca aactcgatgc cacgaagttg gtctcgaccg cgctgaagga ggcgggaatc
     5761 gcggaagccg atgccccgct cggccagccg gccgtcaccg gcatcgacag cgacctctga
     5821 catctccgac acgccaggga gtcgtccggt atcggcttac aaggatgatg cgggggcata
     5881 cggacagcac ccttcgagag gagcttgttc atgcttggca tagctgcggc ggtgctgttc
     5941 ttcatcgcct tcctgatcaa cgcggcggac atcagcacca atgaggcgtt ctcctcgacg
     6001 aacttgatgc tgctcgggct cacggccctg gctctacagg ttgcgggcat aggcgccggc
     6061 cggagcggta gacggcgctc ctgacaccat gccgcgacag ccgctcgaac ccccgcgtag
     6121 tcgcggccag cggggcccac tgagtgatga cgggtaagac ttcccgccac gcgagggggt
     6181 agccctgcat cgaagtacac ccccgccccg gggtgccctc cagccgccat cggtctggag
     6241 ggcaccccgg ggcgggtccg catggaccta cgtcacgacg tacgacggtg acgtggatgc
     6301 gggttgatga ctttgcaggg cggagggccc gtcggcgccc ccacagccag caccacacgg
     6361 agacgttgct gggggagcaa cagggtgatc gacaacgagg cgtgagtact cacccactga
     6421 acgccccgca agctccaacg acatgctcag caccccagga acggcaagtc ccgtggcttt
     6481 acccgctcgc gcggcccggc ccggagcacc acgtccagcc ctcgcgccgg ggcagcggca
     6541 tacgcagggg agaaccacgc catgttggcc tccaccacgg cccaccggta gccgcccggt
     6601 atgggtcgag cagttgcccg acgtccacca cggcggtgct cggcatggcg gcccccgccg
     6661 cagccaccag gcggtcgacg acgtcggcga tctccacgcc agccaggcat ccggcggctc
     6721 gagcaacgcg aacccaacct gtcccgccag ccgtgccccc gccgtcggcc cgccggcccc
     6781 acggtcgcac tgatctcctc cgccgccagg accgtcattc cccgccccac agcctcaacg
     6841 gccaacagcc ccatcgtcga agcccgccga ccaggcatga caagcaccgg aaccctcccc
     6901 gcgatgtgcc cccgccccgc cccagccgca gccgagtatc cgatccgacc cgacccgtgg
     6961 agcaggcggt ggagctgagc ggtcgcctac gactcgtaca gcgccgtgcg ccggtcgggt
     7021 caggcggcgg tggcgaggcc gacaccgatg gcgatgaaca gacagcctgt ggtcagctcc
     7081 cagcgatacc gcaccttcgg ccgggccagc aaagctcgca gccgtgcggc gatcaggacg
     7141 aggacgaacc agtaggcgac gccgatgagc acgtcgagaa tcccgagaaa gaggatctgc
     7201 cgccacagcg aaccattgct gtcgacgaac tgcggcagga cgctcaggaa gaacagcgca
     7261 gccttggggt tgaggacatt cgtgaggagc ccctcggtga agccggaacg ccatcgcctt
     7321 gcagcggcct tgccctccac ggccggacga cgtgcaggac agtcgcccac gtccggtccg
     7381 ccagatgccg ccgcgtcacc gggccgctgc tcctgcacgg cccgcctggc ggcgcgaacc
     7441 gcccgtacgc cgagatagat cagataggca gcgccgagga gcttgaccgt gtcgtacacg
     7501 acgggatagc gggaggctac gacggcgaga ccgatggcgg cagcgaacat gtgcacgcac
     7561 aggccggctt gcgcacccag cgcagcggcc cgccccttcg acggggcctc cgccgccgcc
     7621 cgcaccacga cgagaaagtc cgggccgggg accacatacg ccaccagcac gacgccgagg
     7681 aatccgacga ggtcgaccga cattcgttcc cccgttcgtc tgtccccagc aaccttcttg
     7741 gcggtacgag ttcggctacc ccgtcgtgac gcttcgaccc cggccagacg gggacgacag
     7801 ccagctgcgg ttccgccccc accgcgctgt acccggttcg acgggccccg cggtcacccc
     7861 cggagctggg accaggggtg ccgtgagggt gaaaagggct ggcgcccgga gagagcgccg
     7921 cttgggttct gccccgatgt cgtggtgtct ggtgtcgacc tggatatcgt ccacttatgt
     7981 gtccggcctc gggctgtcac gtttctgcgg tgaaatgctg cctccgggcg ggtgaggcta
     8041 tgcgtccaga cctgttggca cgggccccct gagcattaca aaccgggcat gatcaggaat
     8101 ctgtcgagga gcttgtgcac gctcctcctc gcgctcgtgg ccctctcgcc cgtacccgcc
     8161 tccgcagccg acggccggcg cggggccgag gccgtccgcc ccgaccccgt cgtcttcgtc
     8221 cacggctgga actctgacgg gtcgacctgg cggaccatgg ccggccgctt ccaagcagat
     8281 agctggccgc tcgaccacct ggatcagtgg acctatgacg ccacgcagtc caatgccaca
     8341 accgctgcgc ggctggccga ggagatcgac cgggtcctgg cgcgcaccgg cgcggccaag
     8401 gtcgacatcg tcacccactc gatgggcggg ctgtcctccc gctactacct caagaacctc
     8461 gggggcactt ccaaggtcga cgcgtgggtc tccctggcag ggcccaacca cggcaccggt
     8521 gccgcacgct tgtgcggcgg cgatccgtgc gtcgaaatgc gaccggggtc cctcttcctg
     8581 aacgccctca actccggtga cgagactccc ggctcccccc gctacgccac ctggcgctcc
     8641 ccgtgcgact tggtcatcag ccccggggac agcgtcgccc tcgccggtgc ggtcaacagc
     8701 acgaccggat gcctcggcca cagcgagctg caggccgacg cagcggtata cgagcaggtc
     8761 aagcagcaca tcagctagac gatggccctg tgggtgcgga accggcccag ccctggcgct
     8821 gttgagaagg cggcatcggg gctcggatgt gaccggggca tccgggaaag ctccttcgga
     8881 tgcccgcccg ccggcggtcg gcggaccaat ggcgcgccgg cgcgctaccc gtggctggcg
     8941 aaggcggccg cgtgcctccc cccgcggcaa ccgaggggga gggccgcgca cctgccggcc
     9001 gccataccga aagcgcgccg agcgcccgcc ggttcgtctc atgcgggcgc gtcggccggt
     9061 tccctggtca ggccgcccag tcggctcttc gtagcgacgt cggccaaagg ggaggccacc
     9121 gaccggaccg agtccgaccg gctgcggcac gtagggatcg aagccacatg atctccaacc
     9181 accggaaggg actgctgccg tccctgggct tggccggcgc gaacgactga gacgctgact
     9241 acccgatgag ctgttccgcc acttggcgat acggcttcga ccggacttcc gtcagtttcc
     9301 acagagcagg caggccgtcc ttccgtagcc ggtcctccgc ctcctgctga caagccagtt
     9361 caaagcgggc caggctgtcg aaggagctga cacggacggc ggacggccag gctgccgccg
     9421 ccttcgaggc gaagtccagc gtctgctcgg ccaggatgct ctgttgttcc ggcctggtca
     9481 gcaccgctgt gccgaaaacc agagacgtcc aatccttgac gagtgcatag cccgggagcc
     9541 ctgtctggta cctggcatcc aggtaccagc tcccggcaaa cgcagcgccg agcaagccgt
     9601 cgtcgagttc gtggccgttg agaaatgccg agatgctctc cactcccgcc atgatcggga
     9661 tgtagtgatc aagtaggccg tcccgctcgg tcagcacctg caccgctccg cccagccgga
     9721 cggctgcggc gcagcacagc gcttgtccca cggcgtcaga cgcctcgtcc acgttccccg
     9781 tcccttctcc aaccccgacg tgggccccag gcacgataac cgcaagagcg ccctgagaag
     9841 cgaggcgctc gacgacccga acacgggagc gtccaggccg agtacagagg cgacccgcaa
     9901 ggagtcggcc cacggcgagc cgacgaagac atcgggagct cagccggact tccggcccgg
     9961 gcgcccgtag gctcacagcc gacgacgaca ggagatcggc atgtggaagc gggcgctcga
    10021 ccgagccggg gtcaacgagc ggcggttacg gcgggattac acggagcagc ggcggcaggt
    10081 gcggaggtac aggaccgccg agtacgcggc cgcgcggttg ctgcttccag ccgcgctgct
    10141 gccgcatgtc gtggcagccg tcgcgttcat gcacgacacc gacgaccgga tcgaccgcgg
    10201 tgcgccgcag gaacgggcgg ccgcgctcgc ggaatgggac gcgctcgtac ggaaggccct
    10261 tgccgaaggc gactccgaac tgcccgcgct ccgttgtctg gtgcacaccg ccgcgcagca
    10321 cccggacgta cgcgcctacg tggacgagtt cctgcagggc tgcgagcgtg aggtcgcgtg
    10381 gcggagcatc gcggacgacg aggagctgga ggagtacgta cgggagtact gcctgcccgc
    10441 gctgatgctc acggcctgcc tcctcgcgcc ggcggacgcg tcggaacggg ccgcgttcgt
    10501 ggacggctgc catcggctca tccgcgccat gcagcgcatc gacttcctgg aggacctccc
    10561 ggaggacgtg cgcgcgggcc ggccaggtat ccccgccgac gcggtggccc gccacggcgc
    10621 ggacctctcc cggcccggcg ccgggctggg ccggctcgtc gaggagcagg cggaccgggc
    10681 cgccaccgac ctggcggcgg ccggtcccct cgcggatgtc gtcgaccttg cgtatcggcc
    10741 tttcctccgg gcgctcgtag gcgtccagca cctccggctc aacgcggtac gccgcgcggg
    10801 cgcgtccctt gcgacgagga gctccggccc cccggcaccg gcggccgccg ctctcctgct
    10861 gcgcgagacg gcggcacggg cccggcaggc cgtacgcctc gggtccgacg cctcacggcc
    10921 ctactcgaag cccgccaaca cctgatccgt tgccgttgaa catggcttgg cccatgagat
    10981 gagacagctc tgcgacagca gggccgccgg cacctagcca cggcgccggc gagccgtgcc
    11041 caagggattc gactgcggct cactccgaga gggggctgac cgagcgcgac gacagtcgtg
    11101 cgggggctgt cgcacccacc ggaaccgtct cgagtgcccg agccgatttg gcgcggcctc
    11161 gccccctcct cgtcatgggc cgggcgcgcc aaggggcgga tgcgagccga cgtcagtgtc
    11221 gggggaggcc cgcagcttcc tcccggccgg gcccctgcgg tcggtcccat ccctccggtc
    11281 cgtcctatcg ctccggttcg tcgaaatcct ccgggccgga ctcttcccgt ccgtccgacc
    11341 gcgagcccga cacctcggcc agcagttcgg gcagcgtgcc cgggaagtgc cacagccggg
    11401 gtaggagcgc tgcccaccac tcggcgggga cacccccgtt gctccagcgg gccagcaggg
    11461 cggccgtctc cacgtggagg gctgcacggc cgctccaggc tgcgcgcgag acgtcggccc
    11521 agccggagtg ttgtccgacc cacgaggtca gcaggctcgc gggacgcatc agggggaccg
    11581 cctccgccgc cgacagctgc ccgcgttcga gaaccgcgct gagatggccg aggtgggggg
    11641 cttccgggtc ccggtgggcg tcgtagacga cggtcatcgt ccgcagcgcc tggcgggccg
    11701 aggcggcggt gtcgccgaac ggtcccgtgt cgccgggcgg ctgccacggg gggacccagt
    11761 ggctgtcggg gcgccggggc ggctgtcgta cctctgcctc gcgagcgggc ggcggcaatg
    11821 ggcgaccggg gacggccggt cggccggtcc tgagaacgac tgcgacctcg ggcgggcact
    11881 cggggcgcga gcgcaggact tccgctgccg tacgcggcag ccgatggcct aggcgggccg
    11941 ccgcgaccag gcgccaatcg atgcggtacg gctcctcaag gatcgaccgc atgacctgtt
    12001 gcaccttcca tggcggggag tccgggcgat gcgcggcgcg caggcggcgc agcagcgcgc
    12061 ccgtcccgag ccgtcgctcg gccgcgcagt cgaggaacgg ctccggatcg gcctcggcgc
    12121 aggccgcgac gacatcggcg tcggcatctg tcggaccgcc gcggccgggc agcagtccgg
    12181 ccagttctcg tactcgtgcc gttcctcccg cggcgcgtac ggtctcccag gcggtggcgc
    12241 gagccgtagg cgggtgctcg ccacgcaggt cgaggagggc ggccgccgca agggcggcgt
    12301 cgctcgagaa cagggcccgc cgatgatggc cctggtggta cgaacggctg gtcgcggcgg
    12361 cgatgggatc ccgtacccgc aacaggcaca gcgtcgcgta ccccagccgg tggttgccca
    12421 gcagtgccgc gccgacctcg ggtacgtcga ggtcgaacag tgcccgctgg gtgccttcgt
    12481 ttccgacggt gtgcgcgagg gcggcccgca gccttgtgcc gcccagccgc aggacggcct
    12541 ccacgacggg ggcgggcggg tcgaacccca tgaagaacag ggtcgggtcg atgtccaacc
    12601 aggcctccag ggcggcgggc cgctggtggt acgggatcag cgtcgccagg caggagaggt
    12661 ggaaccggtt ggtcatccgc tggttcgggg tcatgtcctc gtacgcacac gccccagccc
    12721 gcttctccgg taccgcaacc accgagcccc cgttccgccg accccccaca ggtccggcct
    12781 gtacgcatac gtcgggcccg caaccgccta ccgaccccac acaccgcggg atccgccgca
    12841 gtcgccccgg ataccgctct gccttacgcg gtggtgtccg cgagacgcgg cgactgcgcc
    12901 tgcgccttct gggcccggtg agtctcgtcc tggacgagca gggagagcag ggaggcgacg
    12961 ggcaggcccg cttccgccgg gtggcgcagc actttgccgg gctcgatgcg gtaggtgttg
    13021 ctgcgcccgt cgcgggtgtg ggagaggtaa ccgtcctgct cgagatcgga aatgatccgc
    13081 tggacggccc gctccgtgag ccggcagtgg gcggcgatgt cgcggatccg gacgttcggg
    13141 ttgtcggcga tcaccgccag cacgcgtgcg tggttggtga cgaacgtcca tccgttgtgt
    13201 gattcaggca ctccgaccat gacctcattc tacggaacat ctttgccgga cacctcatac
    13261 atgacatact tttcgcgtaa cggatggcat gattccgcgt gagagccaca ggaggggtcc
    13321 gaagatgcct ttgggcgatg ccgtcaccac accacgttgc gcggacggtg cgggcgggga
    13381 ccgagcaggt gagcagggcg tcgtgagcgt cctggagcgg gctgcggtga cgcagtacga
    13441 gagacacggc gcgtgcgtcg tcgtccctcg tggctcctac gacatggagt cgatcgaccc
    13501 tctggcagct gtgctggccg ccgcgtccgc ggagcaccgg ccgatcgtcc tggacgcctc
    13561 cggcatcacc ttcgcggact cggcgctgtt gaacctgctg atcctcaccc gcaaggaggc
    13621 cgaccttcgc ctggccgcgc cgacaccaca gctgcaacgg atcctcgaga tcaccggagt
    13681 cgacaccatc ctgaaggtgc gtacgacggt ggaggacgcc gctgcatgcc cggccgacgg
    13741 acggtgctga gaaccgtgat ggcgcccgcg cgccggctcg gccggtgtcg ccatcgagtg
    13801 ggcgacactc ggtgaaagag ccgtccggtt gcggcaggtg atctctacgc cgggatgctt
    13861 gcccagccag ccagccagcc agccagccag ccagccagcc agccagccag ccagccagcc
    13921 agccgggccg acaggcgcgt ccggtgaggt gcagtggcac ggcgcggcac ggcacggcac
    13981 gacaagctgg ccggccagcg atccggtcgg ccttgctctc ggcgacaccc gcagaccgct
    14041 gctgacgaca ccaacagcca ttcttgtact tgctgccgca gggcccccgc gcacattcgc
    14101 cgggaggcct gcggcagcaa gtacacgcgc caagcgcgcg tgggccagtc ggatatgtgg
    14161 ccgtaggagg cagcttacga acggcttccg gtgccgtccg gccagctggt ggcgctcacg
    14221 cctgcggtgg cagcccctac ggccgcgccg ctcagactcc ggccgtggcc gcctcggcgg
    14281 gctctccgtc tcgtacctgc gccgcggcag gggcgtgggc ctcgggcgtg ggccaggtgt
    14341 agaggacgac cccctgccgg gtgtccttct ccagaccgtc cttcaccacc agcctctcca
    14401 gggtgttgcg gacaacctgg tccgacgtcg tgcgctcggg gtgggccgcc ttcagctcgg
    14461 agccgatctc gctgaccttc ttcggctcac cgggctgctg ggccagaagc tccttgagga
    14521 gctcgccgag cgtggggccc acggacttca cggtcttctt ggccgaagcc gccgtggcct
    14581 tcttgacggc cgtcttcttg gccgccggcg cctttccgga cgcagccttc ttcgctccct
    14641 gagtctcctc gaccgcagcc ttctcgacgg tcggcgcctt ttcggccgga gcctccttgg
    14701 cggccggaac ccccttggcg gccgaagcct tcttggccgc gggagccttc ttactggccg
    14761 gagccttcgc ggtggcacgc ttggccgccg tggccttctt cgccggcgac ttcctcaccg
    14821 aagcggtgcc cccggtcttc tccgccctcg gctgcggaac ggccgccgcc tccgtgccag
    14881 cggcaaccgg agcggtgctg cccaccgact cgacatctgc agccgtttca ccctcgacgg
    14941 ccgtcggcag agactccagc gtcttggtga gccacttctc ctcctcctga agctgactca
    15001 gccgcactgt gagcgtcgcc tgttccgcct ggttggaggc gagatcagag gcgagctgct
    15061 ccgcgtactt gttctggatc gaggtgttga ccggctcgtt ggccatgcaa tccacactcc
    15121 ttttcgggat cggtactgct gccggatgct actcgccaca accccgcatt cgggtggaac
    15181 ggcccacaac actcgttaga ggatgcctgc gtgctgcgca gacagccaag gcaccagacc
    15241 gcgccgggta actccacgac cgaccgacgg gcccgccttc ctctcggaag aggcactgct
    15301 gtcgcctgac ggcatcagga cccgtatgtc ggagaacggg cagctgtcca agcccggttg
    15361 cgtatcacct gtgcgggagc gggatgcctg ccccttgctc aaatcccaat gtttgagagc
    15421 catttgggcc gggtgatgaa atgcggcttc gagacctccg ccgagtgggg ccctgtccaa
    15481 ctgagcaacg gggtcacact ggacttcgcc gccgttccgc cggagacgat caccccccag
    15541 cactacgcct ttctggtctc cgaggaggaa ttcgaggcgg cgtacgcgcg gatcctgcac
    15601 cgtggtatcg agcactacgc cgatccccac cggaagcagc cggacgcgat caaccaccac
    15661 gacggcggcc gcggggtgta cttcgtggac ccggtgggtc atctcctcga gttgatcacg
    15721 gtgccgtacg gcggttggac ctcgtcgccg catacctagg gctgcacccc aggaacgcgg
    15781 tctgcggaac gcaaccgctg aagagaggcc ggccgggcgg ccggaagcgt cgccgccgcc
    15841 cgtggtcggc tctgggatca cggcagttgg cgcatcggcc aacctgcgtt tctgtgactt
    15901 gccctccatg aggggcgtcg ttgaagaggt cattccccat gccttggagc gcagcacctc
    15961 gttcatggcc atgacaccga cgcggagtgg gatgagttcg ctcgtcccac tccgaaggag
    16021 tcatcgcctt gagaaacttc cttcgccgga tcggcgtcat cgccacgggc accgcccttc
    16081 tcggcggcgc actgtccgtc tcaccggcag ccgcagacga catcgtcgac gtccaactcc
    16141 tcagcatcac cgacttccac ggctatctgc agccgcccac ggccgggcag ggcggctcca
    16201 tccccaccgg gcgcggtacc tcggtcaccg tcggcggcgc cgcctatatc gccacccatc
    16261 tccagcggct ccgtggcgac cacccccgtt ccgtcacctt cgccaccggt gacagcttcg
    16321 ccggctggcc cttcgaagtg gacgccttcc aggacgaacc gacgatcgag gtcctcaaca
    16381 agctgggcgt gcgcttctcg gccatgggca accacgagct cgacgtctcc gcggacttcc
    16441 tggttcagca catggaagag ggccggtgct tcggcaaggt cgacgtggac agctgcttca
    16501 cggacagcac cggccggcgc ttccacggcg ccgacttcga cttccagtcg ggcaacatcg
    16561 tcgacgcgcg gaccgggcgg ccggtggtgg atccgtaccg catcgagtgg ttccgctccg
    16621 ccggtggcaa gcggatcccg gtcggcttca tcagcaccac ggtggagggt tccgtcacga
    16681 actcgacgtc cttccagccg cagctgcgcg ccctcgacca ggcacggacc atccagcgct
    16741 acaccaagga actcaagcgg cgcggcgtcg aggccatcgt cctcaacgtg cacgaagggg
    16801 gttcgccgac ggatcccgcc accgcgggct acaacgcgtg cgactccgta ttcggcccgg
    16861 tcttcgaact ggcgaagaag gtccccgccg agatcgacgc gatcgtcacg ggagactggc
    16921 actggcgctt caactgcatg gtgcccgacc cggccggggt accccggccg atcgtggaag
    16981 cgggcaacca cggcgctgtg atcaacgaga tcaacctgtc tctcgatccg aggaccggcg
    17041 atgtcctcag ggaccgcacc cggtccgtga accacgcggt gacgcgtgac gtggcgccgg
    17101 acagcgccgt ccagaagatc gtcgactact gggtcgcgcg cggagcccga cggttcgccg
    17161 agccgctggc ccggcagacg ggttccttca cccgtacacc gaacgcggcg ggggagagca
    17221 cggctgccga cctgtacgcc gacgtgcagt actggaacgc caaccgcacc cgcgcggggc
    17281 aggccgatct ggcgctgatc tccgcgcggc cagccaaggg cagcaacgcc gtacggggcg
    17341 acctgccgtt cggcaagggg agccaccccg ccgacgcgga cggacgcatc ctgttcggcg
    17401 agtcctggaa cgcgtacggc tacggaaacc cggtcctcac cgtcggcgta cgaggacgtc
    17461 agctcgacgc gatcctcgaa cagcagtggc agaagcaggc cgacggctcg gtgaagttcg
    17521 cgccgctcgc cgtgtcccgc aacgtctcgt acagctacga cgcggcccgg cccgtcggtg
    17581 accgcgtctc ccctcgcgac gtggtgatca acggccggcc tctcgatccc gcccgaacgt
    17641 accgggtggc cgctctcgcc tacacggtcg tcggagccga cggatacggg gccttcgccg
    17701 gctacaccga acccgtccgc aacggcgccg accacgaaag cttcgtggag tacctcaaga
    17761 cccacaagac gatctccccc gcacccctca accgcatccg cgtcaagagc tgacgcgaca
    17821 gagcatcccc gccgccgcac gcgcacgcgt gctgaccctg ggagggggcg gacgccggta
    17881 cccccgctgc cccgtcgacg gagcgagggg taccggcgcc tgcggcattc gagaggttca
    17941 gtgctcgcag agggagaacg ctcgttcgta gagctgctcg ttgtgttcgt cgacgaagaa
    18001 cttgcgctcc tgcatgagct gctcgcggta gtccttggct tcgtcaagcg tcattgtcga
    18061 ggattcggac caaggttgtt gcggcggcac ctcggatgtc gagacgatcg tttccgacgg
    18121 gtcgaccagg aagaacgcga gaattttacg gtgtcccggg cgggcggggt ccgcgaggct
    18181 gaacgggccg acgcggtgtt gcaggatgtt cgggaacgcc aggcagcggc ccgcaggcgt
    18241 cgatgccgct ccgagtacct ggttcagtgc gtcttcgtcc tccaggccgt agacctcacg
    18301 caggccgttg tcgtcgttct gctcgtagga cgggtcgtcg agtgccgtcc ggaagctcag
    18361 ccggctctcg gtgatgttct cgctgtccca gtagtagatg ccggtcgaga cgatgcgctc
    18421 gttcatcatc ccctcgacat gccaggaacc gccggggtac tcaggcttgt ccggggtcag
    18481 atgaatggtg gcgagcttga cgatgacctg gagacgacgg ccgcgcaggt cgacccgggc
    18541 ggattcatca ggcaactcgg gcgcggtgaa ggccggcgcg tccgggacga ccgggcggcg
    18601 gttctcccac cagtcgtcct gagccatttc ccacgcacgg acggcttccg cgtaggcccc
    18661 gtcctcactg taggaggacc tgtccggata ctccggctcc gagtcgtacc acccgtaggg
    18721 atcggcctcg atccgcagcg gtcgcggatg gcgcagatcc gtgagcacgt tctccagcag
    18781 cgggcggaag cgggcgaaca cgtccggcag gacagacgcc agttcgtgat ggatctcggg
    18841 gtggacgttg ttgatgtacg agcggaaggc gacgtcgccg tcatcgttga cgtcgacatc
    18901 cgtgggcagc cactggaacc tttcggagaa ttcgtacttc gaatagcggt ccgccgggtt
    18961 ctgccacgcc cggtccggcg caccgctcac acccctcacc aggcagaaca gtgagggatg
    19021 aaccagatca agtacctggc cgtcggatcc gggatgccag tcccgctctg cttcgggaac
    19081 ctgctccaga acccgcacgg cttcgcgcag ccgggacctg agcttgtcgt cgaccagcgt
    19141 gtccgactgc cacaccccgt cgactgcgga tacctcgacg ccggtccctc cgtcccgcaa
    19201 cccggcgtaa tgcacgagtt cggcaagcac atgacgaacc tgcgcttcgg tgaggccctg
    19261 ggcgagagcc tcccgcgtcc acctggcgac gatgtcggca tcgtgcatct tctcgaacca
    19321 ttccggcttc gcccgaatgt gtgcgctgca ctgcatcatc tgaagttccc tcagcgttcg
    19381 cggtgtcgcg aacgacaggg aacgggaggc acgaaagggc agcgggaaag cggacaggcc
    19441 ggtcaattct ccggatcctc ccagtcggtg tgcggtgccg ggaaggatac gtgggccgac
    19501 tgacaccgca gccgtggtcc ctgtccccac gggtccgggg gtcaggtctt cgccgcggtc
    19561 gtgcggtgtc cctccgggcc gctctcatcg ccgacgggag acgtacgcga gccatcggcg
    19621 ccccgggtca ctcagggcgg tggaaccgca cctccgggta ggtctcgtcc gggccgtcga
    19681 ggagtggttg gtccttgccc cgcaggtgct cgtcgaagaa cgcggcgacg taggtgcggg
    19741 tgagggccac cgcgcgctcg gccggcaggt ccccgccggg gaggccgaag tggccgagga
    19801 gcacgggtgc gtcggagaag cccaggtggt cggcgccatc gacggtcagc cagtgcttct
    19861 cgccgcccag agccgtccag gtggtgtccc aggaggtgtc ctcgccgccc ggccggtggg
    19921 actcgtcggt gcccagcagc aggaacggac gcccgccgag cccgtcggca ggaagcgtgt
    19981 cccagaacga gccgtccatg ttcacaccgg cgtcgatacg ccggtcggcg gccatcgcgc
    20041 tgacggcgct cgcgccgccg atcgagtggc cggccatgcc gatccgcgtc cggtcgatgg
    20101 aggacgcgta ccgccatgcg gaccgggggc cggtcagccg gtccaggacg aagcgggtgt
    20161 cggcggcgcg agccccggtc accaggtgcc ccttggacca gccgctctcc tccatggcgg
    20221 tgcacgcgac gcaggtcagg gtgcgcccgc ccggcaccga cgtaccggac gactcgtagg
    20281 catggtcgag cgaggcgacg acgtagccgc gggaggcgag gtccacggcg aggctggtga
    20341 gagtgaagcg cggcatgccg aagcctggcg agagcaccac cagcgggtgt cggcccggag
    20401 cggggcgcac attcaccgcg ctgtgcgtac gggcccgcgc cacctgccgc acggatgccg
    20461 ggtcctcgac cggcacgccc tgcagcagca gccgggcctc ctcctgtgtg gcgtacgggg
    20521 cggggcggcc cggcgtgtgc cccgcggccg atgaacgagc cgcggggtag tgcagggtga
    20581 ccatgatttc ccggccgtcg gcctcgggca cccaggggtc ggtgcgggag cggtccacga
    20641 ggtacaggac ggaactcccc accctgtgcg gcccggtggg ggccggcagc cgcacgccgt
    20701 cggccgaccg gtcgggggtg gtggcggggg cgtatgacga ggcgggagcg gcgacggcgg
    20761 tggcggtggt ggccggtaac gcgacggcgc aggcgagaag gacggcggcg gccgcatggg
    20821 tcagtttgtt catgtcgggg acgctacggt cccggccccg ggaccgcgtc cccccacggt
    20881 cgcacccctc gccgggaccg tacacccctg gtcggatgcc ggccttccca gagggcgggg
    20941 aggac
//
