LOCUS       NZ_JAIHBQ010000001     22199 bp    DNA     linear   CON 08-NOV-2024
DEFINITION  Streptomyces lateritius strain Z1-26 tig00001, whole genome shotgun
            sequence.
ACCESSION   NZ_JAIHBQ010000001
VERSION     NZ_JAIHBQ010000001.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces lateritius
  ORGANISM  Streptomyces lateritius
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Kitasatosporales; Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 7761152)
  AUTHORS   Yang,Y. and Zhai,F.
  TITLE     The genome of Streptomyces lateritius
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 7761152)
  AUTHORS   Yang,Y. and Zhai,F.
  TITLE     Direct Submission
  JOURNAL   Submitted (17-AUG-2021) Life and Science College, Hunan Normal
            University, Juzizhou Street, Changsha, Hunan 410018, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Flye v. 2.5
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 235.0x
            Sequencing Technology             :: Illumina NovaSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_019733325.1-RS_2024_11_06
            Annotation Date                   :: 11/06/2024 09:08:10
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,226
            CDSs (total)                      :: 7,130
            Genes (coding)                    :: 6,956
            CDSs (with protein)               :: 6,956
            Genes (RNA)                       :: 96
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 175
            CDSs (without protein)            :: 174
            Pseudo Genes (ambiguous residues) :: 0 of 175
            Pseudo Genes (frameshifted)       :: 57 of 175
            Pseudo Genes (incomplete)         :: 135 of 175
            Pseudo Genes (internal stop)      :: 9 of 175
            Pseudo Genes (multiple problems)  :: 27 of 175
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 17:31:25
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 7327024
            Orig. end                         :: 7349223
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JAIHBQ010000001.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22199
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="26"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..22199
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22199
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:12199](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12199)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            132..2030
                     /locus_tag="K4902_RS33185"
                     /old_locus_tag="K4902_33185"
     CDS             132..2030
                     /EC_number="2.7.11.1"
                     /GO_function="GO:0004674 - protein serine/threonine kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018384451.1"
                     /locus_tag="K4902_RS33185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K4902_33185"
                     /product="serine/threonine-protein kinase"
                     /protein_id="WP_073815532.1"
                     /sec_met_domain="Pkinase (E-value: 1.2e-40, bitscore:
                     138.2, seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSGQQPGRGDTGEIFRPLAADDPTTVAGYRLAAKLGAGGMGKVYL
                     SYTPGGRPVAIKLIRPEFGEDAEFRRRFAQEVRSAQRVQGLFTAPVIDADPEGAQPWLA
                     TAYVPGPSLADAVVAHGALPVETVLLLVAGMAEALHVIHGAGIVHRDLKPSNVLLASDG
                     PRVIDFGIAHAADATSLTGSGVTIGTPSFMAPEQAAGRKVTPATDIFALGQVAAYAATG
                     VPAFGEGTSHGVLYRIVHEEPDLGAVPERLSELVARCLAKDPEARPTLAEVIQLCQEAN
                     AATVLRRPEDWLPAPVSADITARAAAPAPVQTPPPPQTAPAPGYAPTAPSGPPPGHAPT
                     APAGPTAAAYAPTAPAPPAAAPGGYGPPVGQQPGPYRTPPPAHATPVHAYAPTQGPFPT
                     PYQHPGVPGGQPPGAARGKAGRGLLVALAAVLAFGAVGGLTAYVLLKDKGQETTADGGK
                     PTGGTSTGAKPTGDTAGSGPSGQDAGTTPAATGGTPSATPSTGGDPQPADYPGINLTAG
                     YHLTLGDDAMRPQKGEDGGYELSYDTGGYLDAETNGSSMALLDPGQKGSLAACRAETRF
                     TPDVYVNKLSTGRQICVTTGTGHLALVTVRGISPEDSPSTYLTLDVTVWRDAAASS"
     gene            complement(2040..2855)
                     /locus_tag="K4902_RS33190"
                     /old_locus_tag="K4902_33190"
     CDS             complement(2040..2855)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015031493.1"
                     /locus_tag="K4902_RS33190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K4902_33190"
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="WP_073815530.1"
                     /transl_table=11
                     /translation="MPETRESALRGDCANCFGLCCVALPFAKSADFAVDKAPGEPCRNL
                     QEDFRCGIHTRLRPSGFQGCTVYDCFGAGQQVSQVTFGGVSWREAPETAGRMYDVFYVM
                     RQLHELLYYLTEALARPAARPVHADLRGALDRVEALTRSSADTLKQLRVPEVRADVNRL
                     LLRTSELVRATAGGKPRSRRGADLIGKRLRGAKLRGTDLRGALLIAADLTGADLSLADL
                     IGADLRDADLSGADLTGALFLTQPQLNAARGNADTRVPEGFERPAHWTA"
     gene            complement(2957..4597)
                     /locus_tag="K4902_RS33195"
                     /old_locus_tag="K4902_33195"
     CDS             complement(2957..4597)
                     /NRPS_PKS="Domain: AMP-binding (8-441). E-value: 2.8e-66.
                     Score: 215.7. Matches aSDomain:
                     nrpspksdomains_K4902_RS33195_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019884005.1"
                     /locus_tag="K4902_RS33195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K4902_33195"
                     /product="acyl-CoA synthetase"
                     /protein_id="WP_073815528.1"
                     /sec_met_domain="AMP-binding (E-value: 1.3e-68, bitscore:
                     230.2, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEYNLADLFESVVDVVPDREALVYVDHPGTGAERRLTYAELDAAA
                     NRIAHHLTAAGIRPGEHLGLHLYNGVEYLQTVLACLKARIVPVNVNYRYVEEELVYLYR
                     DADLAALVFDAEFTDRVAAALPRTEKLRHLVRVGTPPDRGEGAAALDCVPFAEAEASGS
                     PERGFGARSADDLFIIYTGGTTGMPKGVLWRQEDLFFAGLFGGDPAGEPVKRPEELAER
                     VAAGGSGITFFPAPPLMHGTSTLTAFIALNYGQRVVLHRKYVPEEVLRTLEKEKVSSIS
                     LVGDAMLRPLVDALRGPLRGTDLSALFSLSSSGAIMSDTVRAQLQELMPNVLLLNNFGS
                     TESGSNGRATDDSGPARGFRLHVNERTQVVDPATRAPVAPGEIGRLAQRGHVPLGYHND
                     PAKTAETFFERDGVRWVLLGDMATVDEAGVVTVLGRGSQCINTGGEKVYPEEVEQALKA
                     HPDVYDALVAGVPDARWGSHVAAVVQLRPDAPPLDLEALQTHCRPRLAGYKVPRQLVLT
                     DRIQRSPSGKADYRWARSVAVDADAADTS"
     aSDomain        complement(3275..4573)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_K4902_RS33195_AMP-binding.1"
                     /evalue="2.80E-66"
                     /label="K4902_RS33195_AMP-binding.1"
                     /locus_tag="K4902_RS33195"
                     /protein_end="441"
                     /protein_start="8"
                     /score="215.7"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="FESVVDVVPDREALVYVDHPGTGAERRLTYAELDAAANRIAHHLT
                     AAGIRPGEHLGLHLYNGVEYLQTVLACLKARIVPVNVNYRYVEEELVYLYRDADLAALV
                     FDAEFTDRVAAALPRTEKLRHLVRVGTPPDRGEGAAALDCVPFAEAEASGSPERGFGAR
                     SADDLFIIYTGGTTGMPKGVLWRQEDLFFAGLFGGDPAGEPVKRPEELAERVAAGGSGI
                     TFFPAPPLMHGTSTLTAFIALNYGQRVVLHRKYVPEEVLRTLEKEKVSSISLVGDAMLR
                     PLVDALRGPLRGTDLSALFSLSSSGAIMSDTVRAQLQELMPNVLLLNNFGSTESGSNGR
                     ATDDSGPARGFRLHVNERTQVVDPATRAPVAPGEIGRLAQRGHVPLGYHNDPAKTAETF
                     FERDGVRWVLLGDMATVDEAGVVTVLGRGSQCIN"
     CDS_motif       complement(3377..3424)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_K4902_RS33195_0002"
                     /evalue="3.10E-05"
                     /label="NRPS-A_a6"
                     /locus_tag="K4902_RS33195"
                     /protein_end="407"
                     /protein_start="391"
                     /score="16.4"
                     /tool="antismash"
                     /translation="VPLGYHNDPAKTAETF"
     CDS_motif       complement(4019..4069)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_K4902_RS33195_0001"
                     /evalue="1.00E-05"
                     /label="NRPS-A_a3"
                     /locus_tag="K4902_RS33195"
                     /protein_end="193"
                     /protein_start="176"
                     /score="18.2"
                     /tool="antismash"
                     /translation="FIIYTGGTTGMPKGVLW"
     misc_feature    complement(4690..4704)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 16.75"
                     /tool="antismash"
     misc_feature    complement(4694..4709)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 17.75"
                     /tool="antismash"
     gene            4763..5563
                     /locus_tag="K4902_RS33200"
                     /old_locus_tag="K4902_33200"
     CDS             4763..5563
                     /NRPS_PKS="Domain: ECH (9-258). E-value: 1.3e-54. Score:
                     177.1. Matches aSDomain:
                     nrpspksdomains_K4902_RS33200_ECH.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1023: enoyl-CoA hydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015031486.1"
                     /locus_tag="K4902_RS33200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K4902_33200"
                     /product="crotonase/enoyl-CoA hydratase family protein"
                     /protein_id="WP_221747316.1"
                     /transl_table=11
                     /translation="MGGTEHLTVRREGGTLVLTLNRPEAKNALSLPMLVGLYDGWLEAD
                     ADDSVRSVVLTGAGGAFCAGMDLKALAGEGMEGERYRDRLKADPDLHWKAMLRHHRPRK
                     PVIAAVEGYCVAGGTEILQGTDIRVAAASATFGLFEVRRGLFPIGGSTVRLPRQIARTH
                     ALEMLLTGRPYTAEEAARIGLVGRVVPDGTALDTALDIAERVNACGPLAVEAVKASVYE
                     TAAMSETEGLAAELDRGWPIFDTVDAKEGARAFAEKRAPVYRRE"
     aSDomain        4790..5536
                     /aSDomain="ECH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_K4902_RS33200_ECH.1"
                     /evalue="1.30E-54"
                     /label="K4902_RS33200_ECH.1"
                     /locus_tag="K4902_RS33200"
                     /protein_end="258"
                     /protein_start="9"
                     /score="177.1"
                     /tool="antismash"
                     /translation="RREGGTLVLTLNRPEAKNALSLPMLVGLYDGWLEADADDSVRSVV
                     LTGAGGAFCAGMDLKALAGEGMEGERYRDRLKADPDLHWKAMLRHHRPRKPVIAAVEGY
                     CVAGGTEILQGTDIRVAAASATFGLFEVRRGLFPIGGSTVRLPRQIARTHALEMLLTGR
                     PYTAEEAARIGLVGRVVPDGTALDTALDIAERVNACGPLAVEAVKASVYETAAMSETEG
                     LAAELDRGWPIFDTVDAKEGARAFAEK"
     gene            5637..6605
                     /locus_tag="K4902_RS33205"
                     /old_locus_tag="K4902_33205"
     CDS             5637..6605
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007262478.1"
                     /locus_tag="K4902_RS33205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K4902_33205"
                     /product="Zn-ribbon domain-containing OB-fold protein"
                     /protein_id="WP_073815523.1"
                     /transl_table=11
                     /translation="MTVTPPPEALRAPLVVEFPFTRSLGPVQSAFLTGLRERTVLGVRT
                     GSGEVLVPPVEYDPATAAELRDLVEVAATGTVTTWAWNHEPRPGQPLTTPFAWVLVRLD
                     GADTALLHALDAPGPDAVHTGLRVRIRWAADRIGAITDIACFEPHDSGPAPGPQAHDGL
                     FDAPVTGIVAAARLDYTYSPGRAQTRYLHALAERRTVGERCPSCTKVYVPPRGACPTCG
                     VATTDQVEVGPRGTVTTYCIVNIKARNAGNDAIEVPYVYAHIALDGAGLALHGRIGGIP
                     YDQVRMGLRVEPVWSEDGRYPDHYRPTGEPDADYDTYKELL"
     gene            6602..7672
                     /locus_tag="K4902_RS33210"
                     /old_locus_tag="K4902_33210"
     CDS             6602..7672
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015031484.1"
                     /locus_tag="K4902_RS33210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K4902_33210"
                     /product="thiolase domain-containing protein"
                     /protein_id="WP_073815521.1"
                     /transl_table=11
                     /translation="MTPHRPGREVAIVAFAQSDHRRRTDDLSEVEMVMPVLHEVLRRTG
                     LKTSDIGFTCSGSSDYLAGRAFSFTMALDGVGAWPPISESHVETDGAWALYEAWVKLLT
                     GQADTALVYSYGKSSPGSVRDVLTRQLDPYYLAPLWPDSVALAALQAQALVDAGDTDEP
                     ALAAIAARSREDATANPHAQLPGPRPQGDYVVRPLRTGDCPPIGDGAAAVILAAGDRAR
                     ELCDRPAWIRGMDHRVEAHSLGVRDLTDSPSTRLAAERAGAFERPVDTAELHAPFTSQE
                     VVLAKALRLDDTVRVNPSGGALAANPVMATGLIRLGEAAARIHRGDSDRALAHATSGPC
                     LQQNLVAVLEGENRVR"
     gene            7677..8843
                     /locus_tag="K4902_RS33215"
                     /old_locus_tag="K4902_33215"
     CDS             7677..8843
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019057880.1"
                     /locus_tag="K4902_RS33215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K4902_33215"
                     /product="thiolase domain-containing protein"
                     /protein_id="WP_221747813.1"
                     /transl_table=11
                     /translation="MAKEPVAVVGIGQTKHVAARRDVSIAGLVREAAVRALEGAELTWA
                     DIDAVVIGKAPDFFEGVMMPELYLADALGAVGKPMIRVHTAGSVGGSTALVAADLVAAR
                     VHRTVLTLAFEKQSESNAMWGLSLPVPFQQPLLAGAGGFFAPHVRAYMRRTGAPDTIGS
                     LVAYKDRRNALLNPYAHLHEHDLTLEKVQASPMLWDPIRYSETCPSSDGACAMVLTDRA
                     GAARSPRPPAWVHGGAMRSEPTLFAGKDFVSPRAGRDCAADVYRQAGVTDPRREIDAVE
                     MYVPFSWYEPMWLENLGFAEEGEGWKLTEAGVTELDGDLPVNPSGGVLSTNPIGASGMI
                     RFAEAALQVRGEAGEHQVDGARRALGHAYGGGAQFFSMWLVGDTPPTS"
     gene            9057..9557
                     /locus_tag="K4902_RS33220"
                     /old_locus_tag="K4902_33220"
     CDS             9057..9557
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018550733.1"
                     /locus_tag="K4902_RS33220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K4902_33220"
                     /product="hypothetical protein"
                     /protein_id="WP_073815519.1"
                     /transl_table=11
                     /translation="MSFLRRRSAATPAGPDFDVLAMDPGDWPGNLGAGLLPAPDGSCQG
                     VFLRYDLFGGRGPAMIIGNLPEGSPARELAEGQIPFEVAQLLAALENDEPVEVLDIEDV
                     PVMQGDNLLIVRRLKLSESRISCVQFDRSDNVLVTIASWDRPITDDLYALLKPLPAELF
                     QQG"
     gene            9575..9940
                     /locus_tag="K4902_RS33225"
                     /old_locus_tag="K4902_33225"
     CDS             9575..9940
                     /GO_function="GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015031477.1"
                     /locus_tag="K4902_RS33225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K4902_33225"
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="WP_073815517.1"
                     /transl_table=11
                     /translation="MSARVDSWIWAVRLTKTRSQAAAACRAGHVKVNGERAKPAQPVKP
                     GDEVRLFHGGRERIVEVKELHTKRVGPPVAVEAYVDNSPPPPPREHVAVAAVRDRGAGR
                     PTKRDRRELDELRGRRP"
     gene            complement(10001..12199)
                     /locus_tag="K4902_RS33230"
                     /old_locus_tag="K4902_33230"
     CDS             complement(10001..12199)
                     /EC_number="4.2.3.-"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012382258.1"
                     /locus_tag="K4902_RS33230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K4902_33230"
                     /product="terpene synthase family protein"
                     /protein_id="WP_221747317.1"
                     /sec_met_domain="T1TS (E-value: 9e-83, bitscore: 277.7,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPQPFVMPDFYVPYPARLNPHVETARTHTRDWAREMGMLEGSGVW
                     EQHDLDSHDYALLCAYTHPDCDSEALDLVTDWYTWVFFFDDHFLEVFKRTQDRAGSKAY
                     LDRLPLFMPADPATGMPEPTNPVEAGLADLWRRTVPSMSGGWRVRFAEATEHLLYESLW
                     ELDNINGGRVANPVEYIEMRRKVGGAPWSAGLVEYAAGAEVPDRVAYSRPLRVLRDAFS
                     DAVHLRNDLFSYQREVEDEGENSNGVLVLERFLGCTTQEAANAVNDLLTSRLQQFENTA
                     LTEVPLLAAEKGLGPEECAAVAAYAKGLQDWQSGGHEWHMRSSRYMNEGMVAGPSRLDG
                     VIGTSALDIRTLFGRPAASRLRTLTHVPHQQVGPSLLPEFDLPYPLTLSPHHQEAKRRS
                     EDWAERMGLLDDIWDRPLMDGFDLALCSAGLDPDATLEELELSAEWLTWGTYGDDYYPL
                     VFGRPRDLAGAKRLTERLKSCMSVKDPAAGRALASHPMEVALADLWARTAGPMGPEARL
                     QLRTALVAMLDSWLWELHNQAQHRVPDPVDYIEMRRTTFGSELTMLLCRLRHTEALPSE
                     IYRTGTVRALEHSVSDYATLLNDLFSYQKEIEVEGEVHNGVLVLQKFFDCDYPTAVAMV
                     DDLMRGRLRQYEHLKETEVPVLYEDFGLDQEGRAAFEAYLRELEDWLAGILNWHRSVRR
                     YRAEDVHGGSGNPLVGRGPTGLGTAAARVASLIGSATR"
     gene            complement(12359..14278)
                     /locus_tag="K4902_RS33235"
                     /old_locus_tag="K4902_33235"
     CDS             complement(12359..14278)
                     /EC_number="3.5.1.28"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /GO_function="GO:0008745 - N-acetylmuramoyl-L-alanine
                     amidase activity [Evidence IEA]"
                     /GO_process="GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019883990.1"
                     /locus_tag="K4902_RS33235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K4902_33235"
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="WP_221747318.1"
                     /transl_table=11
                     /translation="MGLLASAALLLPLLSAAPPAGADAPEAGSLQAQFARAAARHGVPE
                     SVLLAVSYLQSRWDGHGGAPSVTGGYGPMHLTDAVTALAGAAPHHSDGEEDPRGDSSRA
                     VRSGAEAPVPAADSLPPRLRTLERASALSGIPAEELRTGTAANIEGGAALLAAAQREAG
                     LPASTDPADWYGAVARYSGADDSATATTYANDVFDVIRTGESRTTDSGQVVTLPAAPAV
                     APATEQVAALGLRRPAGGPVECPPSVACEWIPAPYEEFGDGDYGNHDKADRPTSQSVDY
                     IVIHDTEAVWDVTLKLVQDPTYVSWQYSLRSSDGHIAQHLPLKDVGWHAGNWFMNAKSV
                     GLEHEGFLTSPDSWYTEAMYRTSARLVRYLAARYGIPLDRQHILGHDNVPGTVTSTIRG
                     MHTDPGPYWDWAHYFRLLGRPITPSAGPDASVVTIRPEYSAHQPVYTGCAVAGEACAPH
                     GSGAVRLHTAPSADAPLVKDVGLRPGGQDSTTGVNDTGARASTGQSYAVAERRGDWTAV
                     WYLGQKAWFHNPGKHPTAVNARGLVLTPREGLASVPVYGRAYPEASAYPAGVPVQAVSP
                     LPYRLLAGQRYVVGDRTPGEYYFAPVFDSSGHTVVRGQEDYYQIQFGHRVAFVKAADVR
                     VSRV"
     misc_feature    14512..14527
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 20.43"
                     /tool="antismash"
     gene            complement(14619..15746)
                     /locus_tag="K4902_RS33240"
                     /old_locus_tag="K4902_33240"
     CDS             complement(14619..15746)
                     /EC_number="2.7.1.-"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010060711.1"
                     /locus_tag="K4902_RS33240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K4902_33240"
                     /product="aminoglycoside phosphotransferase family protein"
                     /protein_id="WP_221747319.1"
                     /sec_met_domain="APH (E-value: 1.3e-16, bitscore: 59.9,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYTASSSVSAPPRPQHRIVPAGTGPYLAPAPQAVRPRRWTGGTGT
                     QPISGRIDLSGPQGAQLKRAIASVHRICPEFNPVQVLRRSGRSVLIVGTTGRTTAVAKC
                     LLDHSPAWVERFQHEIASYRSFVRHRPPVRAPRLIAADPENCTLVIERMPGRAAALSRH
                     PVEAPPRADVRAALGAIARLNAWRPPAGTFDAPLDYGTRIARYHELGLFTDRDRDDLQK
                     LLHGLAHAGGRQGMGQFCHGDALLSNILLSPTGPVLVDWEHAGWYLPGYDLATLWAVLA
                     DAPLARRQISQLAQQAGPASRDAFLVNLMIVLTREIRTYETAVQRTMKEAPPAGSVPVP
                     TGALAPGEEQRLLLRRLHDDCAMARRAVRAAVGTR"
     misc_feature    complement(15432..15434)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            15980..17473
                     /locus_tag="K4902_RS33245"
                     /old_locus_tag="K4902_33245"
     CDS             15980..17473
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015031473.1"
                     /locus_tag="K4902_RS33245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K4902_33245"
                     /product="hypothetical protein"
                     /protein_id="WP_073815506.1"
                     /transl_table=11
                     /translation="MTGQTNTRLADLFGLAGWSKGELARLVNRQAAAMGHPQLATDTSR
                     VRRWIDRGETPRDPVPRVLAALFTERLGRVVTIEDLGFVRHGRAGNRQDVRKTDNPDGL
                     PWAPDRTAAVLTEFTGMDLMLNRRGLVGAGAALAAGSVLSNAMHDWLQTDPSRQSVPQR
                     ATDPLHADPAGFDRYEAAPIGSEEIEALEHSVEVFRAWDASRGGGLQRKAVVGQLNEVG
                     GMLAYRHADHLQRRLWGVAANLAVLAGWMSHDVGLEPTAQKYFVIAAHAAREGGDRPRA
                     GEALSRAARQMVHLGRPDDALDLMKLAKDGSGERVLPRTRAMFHTIEAWAQASMGRGQA
                     MRRTLGEAEDLFVSDRRDEETPSWMQNFDEADMHGMQALAYRTLADHDPTAAVPAQRHA
                     RLAIELRHDGHNRSKLFDHISLASACFIADDPEQADRYARLALMAMGETSSHRTWDRLR
                     EMYRLTGQYAGYTRIEHLREEIAEALPQSPVNRPRTGQA"
     misc_feature    16022..16037
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 20.26"
                     /tool="antismash"
     gene            complement(17544..19028)
                     /locus_tag="K4902_RS33250"
                     /old_locus_tag="K4902_33250"
     CDS             complement(17544..19028)
                     /EC_number="3.1.3.16"
                     /GO_function="GO:0004722 - protein serine/threonine
                     phosphatase activity [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1054: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017948354.1"
                     /locus_tag="K4902_RS33250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K4902_33250"
                     /product="PP2C family protein-serine/threonine phosphatase"
                     /protein_id="WP_221747320.1"
                     /transl_table=11
                     /translation="MPSPLFADRPAQQPEPGAVDALISQTRRLRGELVAVRRDAVVDDD
                     DPQQRWQRALCDLAVSQLDDLGAHLGQLRAGVPEQIAPEPLDSDEGPETAPDTGLATDP
                     GTAYGEIPPARTGSLLSRVGSAEWNLLTDEVSWSEELFQIFGRTRESGPMSLDEMPTMV
                     FAEDQPLLQSLVTDCLIDGKPIDGEFRIVRTDGRVRTVHMTGEPVLDADGCTASMWAVL
                     RDVSELRRSQRAVRESRDTLERSRHIEQTERRVAVELQEAVLPPWRGSLRFAHDGPAPL
                     DVAAHYLPAASTGLIGGDWYDALALPDGDALLTVGDLTGHGVAATSSMAMLLGALRGMA
                     VAGIRPAALMGHLNQLLDTSVQPALGSAMCCRYDPVAQTLTWAQAGHPAPLLFRDGTGH
                     LLRRPEGVLLGATTGAVYGEAETRLLPGDLLVLHTDGLTRGSGTGDDTGARRLLALGPR
                     LTGARDAQEGVRAVVEEFGEEQREDDACVMVVRVGR"
     gene            19214..20407
                     /locus_tag="K4902_RS33255"
                     /old_locus_tag="K4902_33255"
     CDS             19214..20407
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019883985.1"
                     /locus_tag="K4902_RS33255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K4902_33255"
                     /product="hypothetical protein"
                     /protein_id="WP_398853704.1"
                     /transl_table=11
                     /translation="MNDDGIGTAGTRTAATGGTGTRTGTGTTGTGTTGTDTRTGTGTTG
                     TGTAVLLAAAPAGRGRAMDAAAVLPALAAVPPGVLTGTATATVVELADPLDPQTVLTRL
                     RAAATTPGPLLVCLAGQLHLDRRQRLPHLALARTTPATLRYTALPWHWLAGELAVRAPG
                     TTTVVADLAADPDVWERLTTAPDLLSLGPGPLLYGRVAPAPRRGEPLAPAYLRSWAELW
                     RSGARLPYATLHAEAAAHAASAVPEAVLLAPAPAPAPVVDQDPHPAILAAAMAGRHGEA
                     ASVAAAWEREALRRHGPRSAQAVHWTEVRADLARLAGEPARSCELWLAAAEARLALGQR
                     TDDPEVEAAVDRAHHQWEQLGDPARARALGPPLIALRQRVPGRQPGALAALTRRMTG"
     gene            complement(20672..21349)
                     /locus_tag="K4902_RS33260"
                     /old_locus_tag="K4902_33260"
     CDS             complement(20672..21349)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) 2-Hacid_dh_C"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015031468.1"
                     /locus_tag="K4902_RS33260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K4902_33260"
                     /product="NADPH-dependent F420 reductase"
                     /protein_id="WP_221747321.1"
                     /sec_met_domain="2-Hacid_dh_C (E-value: 2.2e-06, bitscore:
                     25.8, seeds: 135, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSGMRIGILGTGNVGRALASAWARAGHEVVIGSRRPDDRELRAEL
                     EELTAAGVRIDGSAGAAAHAEVLVNATPGTESVALLTTVGAPALAGRIILDVGVGFLED
                     GTLSHPVVSLGEEIQRAFPGTRVVKTLATVDRKVMVAPHSLAGPGTVFLSGEDATAKKV
                     VRGLVTDLGWSDDAVLDLGGIATARGQEHFALLFIGIAQATGTYEFGIRVVLPAPGGSG
                     PDH"
     misc_feature    21313..21327
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 16.04"
                     /tool="antismash"
     gene            21469..21993
                     /locus_tag="K4902_RS33265"
                     /old_locus_tag="K4902_33265"
     CDS             21469..21993
                     /EC_number="2.3.-.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1111: GCN5-related N-acetyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015031467.1"
                     /locus_tag="K4902_RS33265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K4902_33265"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_241845624.1"
                     /transl_table=11
                     /translation="MAIPPHSAPAPVPAAAPETLGTGRLLLRPVRDSDLDAVTRLWTDP
                     EVRRHLGGPVIESVIRIRRRRIVGAPGFHAVVRAEDGVFLGLVTVEPGARGGETELSYQ
                     FLPEHWGRGYAREAVGAVVARTLEGTPSVVAVTQEANHRSRRLLEAVGLEYAESFVEWD
                     AHQVLYRRHRA"
ORIGIN
        1 cacgaccccg tacacccatg acgtacggac ggacccggct gtccatccgt aggccgcgcg
       61 gcggaccgga ccgccccgcg acggtagggt gccgtccggc aacagaagtc cgcgtgggga
      121 gacaagagtt catgagtggt cagcaaccgg gtcggggcga cacgggcgag atcttccgac
      181 cgctcgcggc ggacgacccc accacggtcg cggggtaccg gctcgcggcc aagctggggg
      241 cgggcggcat ggggaaggtg tacctctcgt acacgcccgg cggccgaccc gtcgcgatca
      301 agctgatccg ccccgagttc ggcgaggacg cggagttccg ccgccgcttc gcgcaggagg
      361 tgcgctccgc acagcgcgtg cagggactct tcacggcgcc cgtgatcgac gccgatcccg
      421 agggcgccca gccgtggctg gccaccgctt atgtccccgg cccgtcgctc gccgacgcgg
      481 tcgtcgcgca cggagcgctg ccggtggaga cggtgctgct gctcgtcgcg gggatggccg
      541 aggccctgca cgtcatccac ggcgccggga tcgtccaccg cgacctcaag ccgtccaacg
      601 tgctgctcgc ctccgacggg ccccgcgtca tcgacttcgg catcgcccac gcggccgacg
      661 cgacctcgct gaccggcagc ggcgtcacca tcggcacccc gtcgttcatg gctcccgagc
      721 aggccgcggg ccgcaaggtg accccggcga cggacatctt cgcgctcggg caggtcgcgg
      781 cctacgcggc gacgggggtc ccggcgttcg gcgagggcac ctcgcacggc gtgctgtacc
      841 gcatcgtgca cgaggagccg gacctcggcg ccgtgccgga gcggctgagc gagctggtcg
      901 cgcggtgcct cgcgaaggac cccgaggcgc ggccgacgct cgccgaggtc atccagctct
      961 gccaggaggc gaacgcggcg acggtgctcc gccggcccga ggactggctg ccggccccgg
     1021 tctccgccga catcacggcg cgggcggcgg ctcccgcccc cgtccagacg cctccgcccc
     1081 cgcagaccgc ccccgcgccc ggctacgcac ccaccgctcc ctcgggcccg ccccccggcc
     1141 acgcgcccac cgcgcccgcg ggtccgaccg ccgcggccta cgcgcccacc gcaccggccc
     1201 cgccggccgc cgcgcccggc ggctacgggc cccccgtcgg gcagcagccc ggcccctacc
     1261 gcacgccccc gccggcgcac gccacccccg tccacgcgta cgcgccgacc cagggaccct
     1321 tccccacgcc gtaccagcac cccggcgtcc cgggcgggca gccgccgggc gccgcacggg
     1381 ggaaggccgg gcgaggactg ctggtcgccc tcgccgccgt gctcgccttc ggcgcggtgg
     1441 ggggtctgac ggcgtacgtc ctgctgaagg acaaggggca ggagaccacg gccgacggcg
     1501 gcaagccgac cggcggcacc tcgaccggcg ccaagccgac cggcgacacg gccggctccg
     1561 ggccgagcgg ccaggacgcg gggacgaccc ccgccgccac cggcggcacc ccgagtgcga
     1621 cgccctcgac cgggggcgac ccgcagcccg ccgactaccc gggcatcaac ctcaccgccg
     1681 gctaccacct gaccctcggc gacgacgcca tgcggccgca gaagggcgag gacggcgggt
     1741 acgaactctc ctacgacacc ggcgggtacc tcgacgcgga gaccaacggc agcagcatgg
     1801 ccctcctcga cccgggtcag aagggctccc tcgccgcgtg ccgcgcggag acccggttca
     1861 ctccggacgt ctacgtgaac aagctgtcca cgggccgcca gatctgcgtc acgaccggta
     1921 cggggcacct ggccctcgtc acggtcaggg gcatctcccc ggaggactcg cccagcacgt
     1981 atctgacgct cgacgtcacg gtctggcgcg acgcggccgc ctcctcgtaa gggggtcggt
     2041 caggccgtcc agtgcgcggg gcgctcgaat ccctccggga cgcgggtgtc ggcgttcccg
     2101 cgcgccgcgt tcagctgggg ctgcgtcagg aacagggcgc cggtcaggtc cgcccccgac
     2161 agatcggcgt cccgcaagtc cgcgccgatc agatccgcga gcgacagatc cgctcccgtg
     2221 aggtcggcgg cgatgaggag cgctccgcgc aggtcggtgc cgcgcagttt cgcgccgcgc
     2281 agccgcttgc cgatcaggtc cgcgccgcgc cggctcctcg gcttcccgcc ggccgtggcg
     2341 cggaccagct cgctcgtccg cagcagcagc cggttcacgt cggcgcggac ctcggggacg
     2401 cgcagctgct tcagcgtgtc cgccgaactc cgggtgagcg cctcgacgcg gtcgagcgcc
     2461 cccctcaggt cggcgtggac gggccgggcc gccgggcggg ccagtgcctc ggtgaggtag
     2521 tagagcagtt cgtggagctg gcgcatcacg tagaacacgt cgtacatccg gcccgcggtc
     2581 tccggcgcct cgcgccagga cacgccgccg aaggtcacct gggagacctg ctggcccgcg
     2641 ccgaagcagt cgtacaccgt gcagccctgg aaaccgctgg gccggagccg ggtgtggatg
     2701 ccgcagcgga agtcctcctg gaggttccgg cagggctcgc cgggcgcctt gtccacggcg
     2761 aagtcggccg acttcgcgaa gggcagcgcc acacagcaca ggccgaagca gttcgcgcag
     2821 tcgccgcgca gtgcggattc ccgggtctcg ggcacggtgg gacggttcct tcgctgatcg
     2881 gggacggact gtccaccgta tcgcgatctc ggtgagaccg atcgcgaaga tcgtccgggg
     2941 ccggttcgga cacccctcag gaggtgtcgg ccgcgtccgc gtcgaccgcc accgagcggg
     3001 cccagcggta gtccgccttg ccgctggggg agcgctggat gcggtcggtg aggaccagct
     3061 ggcgggggac cttgtacccg gcgaggcggg ggcggcagtg ggtctggagg gcttccagat
     3121 cgagcggcgg ggcgtcgggg cggagctgga cgaccgccgc gacatggctg ccccagcggg
     3181 cgtcggggac gccggcgacc agcgcgtcgt acacgtcggg gtgggccttc agggcctgct
     3241 ccacctcctc cgggtagacc ttctcgccgc ccgtgttgat gcactgggaa ccgcgcccca
     3301 ggacggtgac caccccggcc tcgtccacgg tcgccatgtc cccgaggagc acccagcgca
     3361 ccccgtcccg ctcgaagaag gtctcggcgg tcttggccgg gtcgttgtgg tagccgagcg
     3421 gcacatggcc gcgctgggcg agccggccga tctcgccggg ggcgacgggg gcgcgcgtcg
     3481 ccgggtcgac cacctgggtg cgttcgttca cgtggaggcg gaagccccgg gcgggaccgg
     3541 agtcgtcggt cgcccggccg ttggaaccgg actcggtgga gccgaagttg ttgaggagca
     3601 ggacgttcgg catgagctcc tggagctggg cccgcacggt gtcggacatg atcgccccgg
     3661 acgaggacag gctgaacagg gcggagagat ccgtgcccct gagcggcccg cgcagcgcgt
     3721 ccaccagcgg ccgcagcatg gcgtccccga ccagggagat gctggacacc ttctccttct
     3781 ccagggtgcg gagcacctcc tccgggacgt acttgcggtg caggacgacc cgctggccgt
     3841 agttgagggc gatgaacgcg gtcagcgtgg acgtgccgtg catgagcggc ggcgcgggga
     3901 agaaggtgat cccggagccg ccggccgcga cccgctcggc cagctcctcg ggccgcttca
     3961 cgggctcgcc cgcggggtcc ccgccgaaga gccccgcgaa gaacaggtcc tcctggcgcc
     4021 acaggacgcc cttcggcatc ccggtcgtcc cgccggtgta gatgatgaag aggtcgtccg
     4081 ccgagcgcgc accgaagccc cgctcgggtg agccggaggc ctccgcctcg gcgaagggca
     4141 cgcagtcgag cgccgcggct ccctcgccac ggtcgggagg ggtccccacc cgcaccaggt
     4201 gccgcagctt ctccgtccgc ggcagcgccg ccgcgacccg gtccgtgaac tcggcgtcga
     4261 agacgagcgc ggccaggtcg gcgtcccggt agaggtagac cagctcctcc tccacgtagc
     4321 ggtagttcac gttgaccggc acgatccgtg ccttgaggca ggcgaggacg gtctggaggt
     4381 actcgacgcc gttgtacagg tggagtccga ggtgctcgcc gggccggatg cccgcggcgg
     4441 tgaggtggtg ggcgatccgg ttggccgccg cgtccagctc ggcgtaggtg aggcgccgtt
     4501 ccgcgcccgt gcccggatgg tcgacgtaca ccagtgcctc gcggtcgggg accacgtcga
     4561 cgaccgattc gaacaggtcg gcaaggttgt actccaccgt tcctcctgac cccggtacgt
     4621 acggactcgg gcggtcatta gagcgccgta cgccgacggg gggaagagtc cgcgcagaag
     4681 aatctgacta ggtgtcagaa aactattgaa ctgggccccg ggctcctgca acctgttcca
     4741 gaactggaga cgggagaacc ccatgggtgg caccgaacac ctcaccgtgc ggcgcgaagg
     4801 cggcacgctc gtactcaccc tgaaccgccc cgaggccaag aacgccctct cgctgccgat
     4861 gctcgtcggc ctctacgacg gctggctcga agccgacgcc gacgacagcg tccgctccgt
     4921 cgtcctcacc ggcgcgggcg gcgccttctg cgccggcatg gacctcaagg ccctggccgg
     4981 cgaggggatg gagggcgagc ggtaccggga ccggctgaag gccgaccccg acctccactg
     5041 gaaggcgatg ctccgccacc accgaccccg caaacccgtc atcgccgccg tcgaggggta
     5101 ctgcgtcgcc ggcggcaccg agatcctcca gggcaccgac atcagggtcg cggccgcctc
     5161 cgccaccttc ggcctcttcg aggtccggcg cggcctcttc cccatcggcg gctccaccgt
     5221 ccgcctgccc cgccagatcg cccgcaccca cgccctggag atgctcctca ccggccgccc
     5281 gtacaccgcc gaggaagccg cccgcatcgg actcgtcgga cgggtggtcc ccgacggcac
     5341 ggccctcgac accgccctcg acatcgccga gcgcgtcaac gcgtgcggcc cgctcgccgt
     5401 cgaggccgtc aaggcctccg tctacgagac cgccgcgatg tccgagacgg aggggctggc
     5461 cgccgaactc gaccggggat ggccgatctt cgacacggtc gacgcgaagg agggagcgcg
     5521 cgcgttcgcg gagaagcggg cgccggtgta ccgccgggag tgacgtcctc cccggaggcc
     5581 ccgcgcagcg gctcgacccg tacgcccacc gaccgtccca cgaaggagcc cgccgcatga
     5641 ccgtcacccc accgccggag gccctccgcg cccccctcgt cgtcgagttc cccttcaccc
     5701 gctccctcgg ccccgtccag tccgccttcc tcaccggact gcgcgaacgg accgtgctcg
     5761 gagtccgcac cgggagcggc gaggtgctcg tcccgcccgt cgagtacgac cccgccaccg
     5821 ccgccgagct gcgcgacctc gtcgaggtcg ccgccacggg caccgtcacc acctgggcct
     5881 ggaaccacga gccccgcccc ggccagcccc tgacgacccc cttcgcctgg gtcctcgtcc
     5941 gcctcgacgg cgccgacacc gccctgctcc acgccctcga cgcgcccggc cccgacgccg
     6001 tgcacaccgg gctgcgggtc aggatccggt gggccgccga ccgcatcggc gccatcacgg
     6061 acatcgcctg cttcgaaccg cacgacagcg gtcccgcgcc cggaccacag gcccacgacg
     6121 gcctgttcga cgcccccgtc accggcatcg tcgccgccgc ccgcctcgac tacacctaca
     6181 gccccggccg cgcccagacc cgctatctgc acgcgctcgc cgagcgccgg acggtcggcg
     6241 aacgctgccc ctcctgcacc aaggtgtacg tgccgccccg cggcgcctgc cccacctgcg
     6301 gcgtcgccac caccgaccag gtcgaggtcg ggccgagggg caccgtcacc acgtactgca
     6361 tcgtcaacat caaggcaagg aacgccggga acgacgccat cgaggtgccg tacgtctacg
     6421 cccacatcgc cctcgacggt gccgggctcg ccctccacgg ccgcatcggc ggcatcccgt
     6481 acgaccaggt ccgcatgggt ctgcgcgtcg aacccgtgtg gagcgaggac ggccgctacc
     6541 ccgaccacta ccgccccacc ggcgagcccg acgccgacta cgacacctac aaggagctgc
     6601 tgtgacgccg caccggccgg gccgagaggt ggcgatcgtc gccttcgccc agagcgacca
     6661 ccgccgccgc accgacgacc tctccgaggt cgagatggtc atgcccgtcc tccacgaggt
     6721 gctccggcgg accgggctca agacctccga catcggcttc acctgctccg gctcctccga
     6781 ctacctcgcc ggccgggcct tctccttcac catggccctc gacggcgtcg gcgcctggcc
     6841 ccccatctcc gagtcccacg tcgagaccga cggcgcctgg gcgctgtacg aggcctgggt
     6901 gaagctcctc accggccagg ccgacaccgc cctcgtctac tcctacggaa agtcctcgcc
     6961 cggctccgtc cgggacgtcc tcacccgcca gctcgacccg tactacctcg ccccgctctg
     7021 gcccgactcc gtcgccctcg ccgccctcca ggcgcaggcg ctcgtcgacg ccggcgacac
     7081 cgacgaaccc gccctcgccg cgatcgccgc ccgcagccgt gaggacgcca ccgcgaaccc
     7141 ccacgcccag ctgcccggcc cccgccccca gggcgactac gtcgtccggc cgctgcgcac
     7201 cggcgactgc ccgcccatcg gcgacggcgc cgccgccgtg atcctggccg ccggggaccg
     7261 ggcccgtgaa ctctgcgacc ggcccgcctg gatccggggc atggaccacc gcgtcgaggc
     7321 ccactccctc ggggtccggg acctcaccga ctcgccctcc acccgcctcg ccgccgaacg
     7381 cgccggagcc ttcgagcggc ccgtcgacac cgccgaactc cacgcgccgt tcacctccca
     7441 ggaggtcgtg ctcgccaagg ccctccgcct cgacgacacc gtccgcgtca atccctccgg
     7501 cggcgccctc gccgccaacc ccgtcatggc caccggcctc atccggctcg gcgaggccgc
     7561 cgcccgcatc caccgcggcg actccgaccg cgccctcgcc cacgcgacct cgggcccctg
     7621 cctccaacag aacctggtcg ccgtcctgga aggggagaac cgtgtccggt gagcccgtgg
     7681 ccaaggaacc ggtggccgtc gtcggcatcg gccagaccaa gcacgtcgcc gcccgccggg
     7741 acgtgtcgat cgccggactc gtccgcgagg ccgcggtccg cgccctggag ggcgccgagc
     7801 tgacctgggc ggacatcgac gccgtcgtca tcggcaaggc ccccgacttc ttcgagggcg
     7861 tgatgatgcc ggagctgtac ctcgcggacg ccctcggcgc ggtcggcaag cccatgatcc
     7921 gggtgcacac cgccggatcg gtcggcggtt ccaccgcgct cgtcgccgcc gacctggtcg
     7981 ccgcgcgcgt ccaccggacc gtcctcaccc tcgcgttcga gaagcagtcc gagtccaacg
     8041 ccatgtgggg cctctccctg cccgtcccct tccagcagcc gctgctcgcg ggcgccggcg
     8101 gcttcttcgc ccctcacgtc cgggcctaca tgcgccgcac cggcgccccc gacaccatcg
     8161 gctccctcgt cgcgtacaag gaccggcgca acgcgctgct caacccgtac gcccacctcc
     8221 acgagcacga cctcaccctg gagaaggtgc aggcgtcccc gatgctctgg gacccgatcc
     8281 gctactcgga gacctgcccc tcgtcggacg gcgcctgcgc gatggtcctc accgaccgtg
     8341 cgggcgcggc ccgttcgccc cggccgcccg cctgggtgca cggcggcgcg atgcgcagcg
     8401 aaccgaccct cttcgccggc aaggacttcg tctcgccgcg ggccggacgg gactgcgccg
     8461 ccgacgtcta ccggcaggcc ggcgtgaccg acccccggcg ggagatcgac gccgtcgaga
     8521 tgtacgtgcc gttctcctgg tacgagccga tgtggctgga gaacctcggc ttcgccgagg
     8581 agggcgaggg ctggaagctc accgaggccg gggtcaccga actcgacggc gacctgcccg
     8641 tgaacccctc cggaggagtg ctctccacca accccatcgg agcctccggg atgatccgct
     8701 tcgccgaggc cgccctgcag gtgcgcgggg aggcgggcga gcaccaggtc gacggcgcgc
     8761 gccgggccct cgggcacgcc tacggaggcg gcgcgcagtt cttctcgatg tggctcgtcg
     8821 gggacacgcc gcccacgagc tgagccacgg ggggcgcggg gcaccgggcg tgctcaccgt
     8881 ccgtgaggac cgcgcccccc aggtcaccgt ccgcgaccgg ggcgggagcc tcggcagcac
     8941 cgcgccggca cggtccggga gcgccgtgcg aggctcccgg accccgccgc gcggggcccg
     9001 ccgcccggag ccgcccggcg cgtcgcgtcg cgcgcccggg cacgtaccat ggccgtatgt
     9061 ccttcctccg ccgccgcagc gccgccacac ccgcgggccc ggacttcgat gtcctggcca
     9121 tggacccggg ggactggccc ggcaacctcg gcgccggcct gctgcccgca cccgacggct
     9181 cctgccaggg cgtcttcctc cgctacgacc tgttcggcgg ccgcggcccc gcgatgatca
     9241 tcggcaacct gccggagggc tccccggcgc gcgagctcgc ggagggccag atccccttcg
     9301 aggtggccca gctcctcgcc gccctcgaga acgacgagcc ggtcgaggtc ctcgacatcg
     9361 aggacgtccc cgtgatgcag ggcgacaacc tcctgatcgt ccgccgcctc aagctctccg
     9421 agagccgtat ctcctgcgtc cagttcgacc gcagcgacaa cgtcctcgtg acgatcgcca
     9481 gttgggaccg gccgatcacg gacgacctgt acgcgctgct caagccgctt cccgccgagc
     9541 tgttccagca gggctgacgg aggagcgggg gccgatgagc gcacgcgtcg acagctggat
     9601 ctgggcggtc cggctcacca agacccgctc ccaggccgcc gcggcctgcc gggccggaca
     9661 cgtcaaggtc aacggcgagc gggccaagcc cgcccagccg gtgaagcccg gcgacgaggt
     9721 caggctcttc cacggcggcc gcgagcggat cgtcgaggtc aaggagctcc acaccaagcg
     9781 ggtgggcccg ccggtcgccg tcgaggcgta cgtggacaac agtccgcccc cgccgccgcg
     9841 cgagcacgtg gccgtcgccg ccgtgcgcga ccggggcgcc gggcgcccca ccaagcgcga
     9901 ccgccgcgaa ctcgacgagc tgcgcggccg acgcccctga tccgtacggc tccgggggcc
     9961 ggccacggga gcacccccgt ggccggcccc cgtccgtgtc tcagcgcgtc gcggacccga
    10021 tgagggaggc cacccgcgcg gccgcggtgc ccagacccgt cggtccacgg cccaccagcg
    10081 ggttgccgct gcccccgtgg acgtcctcgg cacggtaacg ccgcacgctc cggtgccagt
    10141 tgaggatccc ggcgagccag tcctccagct cccgcaggta cgcctcgaac gccgcccggc
    10201 cctcctggtc gagaccgaag tcctcgtaga gcacgggcac ttcggtctcc ttcaggtgct
    10261 cgtactggcg cagccgcccc cgcatcaggt cgtcgaccat cgccaccgcc gtcgggtagt
    10321 cgcagtcgaa gaacttctgc agcaccagca cgccgttgtg cacctcaccc tcgacctcga
    10381 tctccttctg gtacgagaag aggtcgttga ggagcgtcgc gtagtcggag accgagtgct
    10441 ccagggcgcg gaccgtaccg gtccggtaga tctccgacgg cagggcctcg gtgtgccgca
    10501 gccggcacag cagcatcgtc agctcggagc cgaaggtggt ccgccgcatc tcgatgtagt
    10561 ccaccggatc gggcacccgg tgctgcgcct ggttgtgcag ctcccacagc cagctgtcga
    10621 gcatcgcgac cagcgcggtc cggagctgga gccgcgcctc agggcccatc gggcccgcgg
    10681 tccgcgccca caggtcggcg agcgcgacct ccatcggatg ggaggcgagg gcccgcccgg
    10741 ccgccggatc cttcaccgac atgcacgact tgagccgctc cgtgaggcgc ttggcacccg
    10801 ccaggtcgcg cggccgcccg aagacgaggg ggtagtagtc gtccccgtac gtcccccagg
    10861 tcaaccactc ggcgctgagc tccagctcct ccagggtggc gtccgggtcg agccccgccg
    10921 agcagagcgc caggtcgaag ccgtccatca gcggacggtc ccagatgtcg tccaggagcc
    10981 ccatccgctc cgcccagtcc tcggagcgcc gcttggcctc ctggtggtgc gggctgagcg
    11041 tcaacgggta cggcaggtcg aactccggca ggagcgaggg ccccacctgc tggtgcggca
    11101 cgtgcgtgag cgtccgcagc cgggaggcgg ccgggcggcc gaacagggtc cggatgtcga
    11161 gggcggaggt gccgatcacc ccgtcgagcc gcgagggccc ggcgaccatg ccctcgttca
    11221 tgtaccggct ggagcgcatg tgccactcgt gaccgccgga ctgccagtcc tggagcccct
    11281 tggcgtacgc cgccacggcc gcgcactcct ccggccccag ccccttctcg gcggccagca
    11341 gcgggacctc ggtcagggcc gtgttctcga actgctggag ccgcgaggtc agcaggtcgt
    11401 tgacggcgtt cgccgcctcc tgcgtcgtac agccgaggaa ccgctccagg acgaggacgc
    11461 cgttgctgtt ctcgccctcg tcctccacct cgcgctggta cgagaagagg tcgttgcgca
    11521 ggtgcacggc gtcggagaag gcgtccctga ggacgcggag cggccgggag tacgccaccc
    11581 ggtccgggac ctccgccccc gccgcgtact ccacgagccc cgccgaccag ggcgcgccgc
    11641 ccaccttgcg gcgcatctcg atgtactcca cggggttggc gacgcgcccc ccgttgatgt
    11701 tgtcgagttc ccagagcgac tcgtacagca ggtgctcggt cgcctccgcg aaccgcaccc
    11761 gccagccccc ggacatcgag gggacggtac gccgccacag gtcggcgaga cccgcctcca
    11821 cggggttggt gggctcgggc atgcccgtcg ccgggtcggc cggcatgaac agcggcagcc
    11881 ggtccaggta ggccttgctg ccggcccggt cctgggtccg cttgaagacc tccaggaagt
    11941 ggtcgtcgaa gaagaacacc cacgtgtacc agtccgtgac gaggtcgagg gcctcgctgt
    12001 cgcagtcggg atgcgtgtac gcgcagagca gcgcgtagtc gtgggagtcg aggtcgtgct
    12061 gctcccagac gcccgaaccc tccagcatcc ccatctcccg cgcccagtcc cgggtgtgcg
    12121 tgcgggcggt ctccacatgg gggttgagcc gcgccggata cggaacatag aaatccggca
    12181 tgacgaaggg ctgaggcatg tgcggagggg ccttccggtg agcaagtgcg gtgtccggcc
    12241 cacctttacc cgtcgcccgt acggcgcacg cgatctcttg aatagtccta tgaacgccga
    12301 aggggtggtg ccggccccct cctccggcac caccccgcgc gtttcggcca cgcctccgtc
    12361 agacccggga aacccgcacg tcagcggcct tcacaaaggc cacccgatgg ccgaactgga
    12421 tctggtagta atcctcctgg ccgcgcacga ccgtatggcc gctgctgtcg aacaccggcg
    12481 cgaagtagta ctcgcccggg gtccggtcac ccaccacgta ccgctgaccc gcgagcagcc
    12541 ggtacggcag cggagagacc gcctgcaccg gcacacccgc cgggtacgcc gacgcctcag
    12601 ggtaggcccg cccgtacacc ggcaccgagg cgagaccctc ccggggggtc aggacgagcc
    12661 cccgcgcgtt caccgcggtc gggtgcttcc ccggattgtg gaaccacgcc ttctgcccga
    12721 ggtaccagac cgccgtccag tcgcccctgc gctcggccac cgcgtagctc tgccccgtcg
    12781 aggcccgcgc cccggtgtcg ttgaccccgg tcgtcgagtc ctgcccgccc ggccgcaggc
    12841 cgacgtcctt caccaggggc gcgtcggcgc tcggcgcggt gtgcaggcgc accgccccgc
    12901 tcccgtgcgg cgcacacgcc tcgcccgcca ccgcgcagcc cgtgtacacc ggctgatggg
    12961 cgctgtactc gggccggatc gtcaccaccg aggcgtccgg accggcgctc ggcgtgatcg
    13021 gacggccgag cagccggaag tagtgggccc agtcccagta cggccccggg tccgtgtgca
    13081 tgcccctgat ggtggacgtc accgtgcccg gcacgttgtc gtgccccagg atgtgctgcc
    13141 ggtcgagcgg gatgccgtac cgggcggcca ggtaccgcac gagccgcgcc gacgtccggt
    13201 acatcgcctc cgtgtaccag gagtccggcg aggtcaggaa gccctcgtgc tccaggccca
    13261 ccgacttggc gttcatgaac cagttgcccg cgtgccagcc gacgtccttg agcggcaggt
    13321 gctgggcgat gtgcccgtcg gaggaacgca gcgagtactg ccaggacacg tacgtcgggt
    13381 cctgcaccag cttcagggtg acgtcccaga cggcctcggt gtcatggatg acgatgtagt
    13441 cgaccgactg ggaggtgggc cggtccgcct tgtcgtggtt gccgtagtcg ccgtcaccga
    13501 actcctcgta cggcgcgggg atccactcgc aggccaccga gggcggacac tccacgggac
    13561 cgccggccgg ccgccgcagc ccgagggcgg ccacctgctc cgtggcgggc gcgaccgcgg
    13621 gcgcggccgg gagcgtcacc acctgcccgc tgtccgtcgt ccgggattcc ccggtccgga
    13681 tcacgtcgaa cacgtcgttc gcgtacgtcg tcgccgtcgc cgagtcgtcc gcgccggagt
    13741 accgggccac cgccccgtac cagtcggccg ggtccgtgct cgccggcagc ccggcctccc
    13801 gttgcgcggc ggcgagcagc gccgccccgc cctcgatgtt cgccgccgtg ccggtccgca
    13861 gctcctcggc cgggatcccg gacagcgcgg aagcccgctc cagggtccgc agccgcgggg
    13921 gcagcgagtc cgccgccggg accggcgcct ccgcaccgga acgcaccgcg cgggacgagt
    13981 cgccgcgagg atcctcctca ccgtccgagt ggtgcggggc ggcaccggcg agcgcggtca
    14041 ccgcgtccgt cagatgcatc ggcccgtagc cgccggtcac actcggcgca ccgccgtgcc
    14101 cgtcccagcg cgactggagg tacgagacgg cgagcaggac gctctccggt acaccgtgcc
    14161 tcgcggccgc ccgcgcgaac tgcgcctgga gggaacccgc ctcgggcgcg tcggcaccgg
    14221 ccggaggggc cgcggagagc agcgggagca acagggcggc ggatgcgagc agtcccaccg
    14281 cccggggtgg acggagggac gatggacgtc cgggggacgc ggaacggagc aaggcagcct
    14341 ccaggggcgg ggggtgacac cggggcgtgc gggaccgaac ccgtacaggg gtatcggctc
    14401 ccggacgatc cgtcaatcac gcgtccctgg aagcaacttc gcacgtcaga ggcgaaatgg
    14461 gggcggtacg gcggagtttc acggagacgg gcccccggcc agggacccgt cagtggagtg
    14521 gaccactggc tcggtcccca catgccggtg cgccgcgtcc cggtgtgtcg gcaccgggcg
    14581 cacggcgcac cccccgttcc gttggccggc cccgcccttc agcgcgtccc gaccgccgcg
    14641 cgcacggccc gccgtgccat ggcgcagtcg tcgtgcagcc gcctcaggag cagccgctgt
    14701 tcctcacccg gggcgagcgc ccccgtgggc accggcacgg agccggccgg cggagcctcc
    14761 ttcatcgtgc gctgcaccgc cgtctcgtac gtccggatct cccgcgtcag cacgatcatc
    14821 aggttcacca ggaaggcgtc ccgggaggcc gggcccgcct gctgggcgag ctgactgatc
    14881 tgccgcctgg cgagcggcgc gtcggcgagc accgcccaga gcgtcgccag gtcgtacccc
    14941 gggaggtacc agcccgcgtg ttcccagtcc acgaggacgg gcccggtggg ggagagcagg
    15001 atgttggaga gcagggcgtc cccgtgacag aactgcccca tgccctgacg gccgcccgcg
    15061 tgcgccagac cgtgcagcag cttctgcagg tcgtcccggt cccggtcggt gaagagaccg
    15121 agctcgtggt agcgcgcgat ccgcgtgccg tagtccagcg gggcgtcgaa cgtcccggcc
    15181 ggcggccgcc aggcgttgag ccgggcgatc gcgccgagcg cggcccgcac gtcggcccgg
    15241 ggcggcgcct cgacggggtg gcgcgagagc gccgccgccc gtccgggcat ccgctcgatc
    15301 accagcgtgc agttctccgg gtccgccgcg atcagccgcg gcgcccgcac cggcggacgg
    15361 tggcggacga aggagcggta ggacgctatc tcgtgctgga accgctcgac ccacgcgggg
    15421 gagtggtcca gtaaacactt cgcgaccgcc gtggtccgcc cggtcgtccc gacgatcagt
    15481 acggagcgtc cgctgcgccg cagcacctgc accgggttga actccgggca gatgcggtgg
    15541 accgaggcga tcgccctctt cagctgcgcc ccctgagggc ccgacagatc gatgcgtcca
    15601 ctgatcggct gggtgccggt gccgcccgtc cagcgccgcg gccggacggc ctggggcgcg
    15661 ggagcgaggt agggcccggt gccggccggg acgatgcggt gctgcggccg gggcggggcg
    15721 gacacggagg acgatgctgt gtacatggag gtgacagatc ccttcgtgtg ccgacgagtt
    15781 gcgtgcgtcg ccccgcccgc ccccggtccg caccctgggg aatgagggcc ggtcggcggg
    15841 gcggggtggc gctttcctac ctgacacccg ggcgcgggtg gcggaacatc gggcgcaccc
    15901 tggcgaaccc tggcgaatag tcgccagccc tatgacagga ggttactgtc aactcagccg
    15961 agaacctggg ggcttagacg tgaccggaca aaccaacacc cgcctggcag acctgttcgg
    16021 cctggccggc tggtccaagg gcgaacttgc gagactcgtc aaccggcagg cggcggccat
    16081 gggccacccc cagctggcga ccgacacctc gcgggtccgg cgctggatcg accgcggtga
    16141 gaccccgcgc gatcccgtcc cccgggtgct ggcagcactg ttcaccgagc gactcggccg
    16201 tgtcgtgacc atcgaggacc tcgggttcgt acgacacggg cgcgccggaa accggcagga
    16261 cgtcaggaag acggacaacc ctgacgggct gccctgggca cccgatcgta cggcggcggt
    16321 cctcaccgaa ttcacgggaa tggacctcat gctcaaccga cgcggtctgg tgggcgcggg
    16381 tgccgcgctt gccgccggct ccgtactcag caacgccatg cacgactggc tgcagaccga
    16441 cccctcacgc cagtccgtcc cccagcgggc caccgatccc ctccacgccg accccgccgg
    16501 gttcgaccgc tacgaggccg cccccatcgg gtcggaggag atcgaggctc tggagcactc
    16561 ggtggaggtg ttccgtgcct gggacgcctc acggggtggc ggtctccagc gcaaggccgt
    16621 ggtgggccag ctcaacgagg tgggaggcat gctcgcctac cgccacgccg accacctcca
    16681 gcggcgcctg tggggcgtcg ccgccaatct ggccgtcctc gccggctgga tgtcgcacga
    16741 cgtgggcctc gaacccacgg cgcagaagta cttcgtgatc gccgcccacg cggcccgcga
    16801 gggcggcgac cggccccggg ccggcgaggc gctctcccgc gccgcccgcc agatggtgca
    16861 cctgggcagg cccgacgacg ccctcgacct gatgaagctg gccaaggacg gctcgggcga
    16921 acgggtcctg ccccggaccc gggccatgtt ccacacgatc gaggcctggg cgcaggcgtc
    16981 gatgggccgt ggccaggcta tgcgccgcac cctcggcgag gccgaggacc tgttcgtgtc
    17041 ggaccggcgc gacgaggaga cgccgagctg gatgcagaac ttcgacgagg ccgacatgca
    17101 cggcatgcag gccctcgcct accgcaccct cgccgaccac gacccgaccg ccgccgtccc
    17161 cgcccagcgc cacgcccggc tggcgatcga gctgcggcac gacggtcaca accgctcgaa
    17221 gctcttcgac cacatctcgc tcgcctcggc ctgcttcatc gccgacgacc cggagcaggc
    17281 cgaccgctac gcccggctcg ccctgatggc catgggggag acctcgtccc accgcacctg
    17341 ggaccggctg cgggagatgt accggctcac cgggcagtac gccggctaca cgaggatcga
    17401 gcacctgcgc gaggagatcg cggaggccct gccgcagtcg ccggtcaacc gcccgaggac
    17461 gggacaggcc tgagcggggg ccacggcccc cgctccacgg tcggtacgag ggcgcgccgg
    17521 tcaggcgacc gccgtcgggt gcctcagcgg ccgacccgga ccaccatcac gcaggcgtcg
    17581 tcctcgcgct gctcctcgcc gaactcctcg accaccgcgc gcacaccctc ctgggcgtcc
    17641 cgcgccccgg tgaggcgggg gccgagggcg agcagccgtc gtgcgccggt gtcgtcgccc
    17701 gtaccgctgc cacgggtcag cccgtcggtg tgcaggacga gcaggtcacc ggggagcagc
    17761 cgggtctcgg cctcgccgta cacggccccg gtcgtcgctc cgaggagcac tccctcgggc
    17821 cggcggagca ggtgccccgt cccgtcacgg aacagcagcg gggcggggtg tcctgcctgc
    17881 gcccaggtca gcgtctgggc gaccgggtcg tagcggcagc acatcgcgct gccgagcgcg
    17941 ggctgtacgg aggtgtccag gagctggttg aggtggccca tcagggcggc ggggcggatg
    18001 cccgcgaccg ccatcccgcg cagggcgccg aggagcatgg ccatcgagga ggtcgcggcg
    18061 accccgtggc ccgtcaggtc accgacggtg agcagcgcgt ccccgtcggg cagggcgagc
    18121 gcgtcgtacc agtcgccgcc gatgaggccg gtactcgcgg ccgggaggta gtgggccgcc
    18181 acgtcgagcg gggcggggcc gtcgtgggcg aagcggagcg agccgcgcca cggcgggagc
    18241 accgcctcct ggagctcgac ggcgacccgg cgctcggtct gctcgatgtg gcggctgcgc
    18301 tccagggtgt cccggctctc ccggaccgcc cgctggctgc gacgcagttc gctgacgtcg
    18361 cggagcaccg cccacatcga ggcggtgcac ccgtcggcgt cgaggacggg ctcgcccgtc
    18421 atgtgcaccg tccggacacg tccgtcggtg cggacgatcc tgaactcgcc gtcgatcggc
    18481 ttcccgtcga tcagacagtc cgtcaccagg ctctggagga gcggctggtc ctcggcgaag
    18541 accatcgtgg gcatctcgtc cagcgacatc gggccgctct cgcgcgtacg tccgaagatc
    18601 tggaacagct cttcggacca gctgacctcg tcggtcagca ggttccactc ggcactgccg
    18661 acgcgggaga gcaacgagcc cgtgcgcgcc ggcgggatct cgccgtaggc ggtgccgggg
    18721 tcggtcgcga ggccggtgtc gggcgcggtc tcgggaccct cgtcggagtc gagcggctcc
    18781 ggggcgatct gctccgggac gcccgcccgc agctgtccca agtgggcgcc gagatcgtcg
    18841 agttggctca ccgcgagatc gcagagggca cgctgccagc gctgctgcgg gtcgtcgtcg
    18901 tccaccacgg cgtcccggcg cacggcgacc agctcgccgc gcaggcggcg ggtctgcgag
    18961 atcagtgcgt ccaccgcgcc cggctccggc tgctgggcgg ggcggtccgc gaacaggggg
    19021 gacggcatgt ggtactccga tacaggcgcg gaacggccag gccgggtgtg aagggtaggc
    19081 ccggatacga ctgttgcaca gcccgggaga gcccgtaagg gatttggcaa cactcgatcc
    19141 ggtggtgctt ctggcatatg tcaacggccc ggcgattacc ggccagtgca caaggcgtta
    19201 cggtgcgggg gtggtgaacg acgacggaat cggcacggcg ggcacgcgta cggcggccac
    19261 gggcgggacg ggtacgcgca cggggacggg cacgacggga acgggtacga cggggacgga
    19321 tacgcgcacg gggacgggta cgaccgggac gggtaccgcc gtcctgctcg cggcggcgcc
    19381 cgccgggcgg gggcgcgcca tggacgccgc cgccgtgctg ccggccctcg ccgccgtgcc
    19441 gcccggggtc ctcaccggca ccgccaccgc cacggtcgtc gaactcgccg atccgctcga
    19501 cccgcagacc gtgctcaccc gcctgcgggc cgccgcgacg acccccggcc cgctgctcgt
    19561 ctgcctcgcg gggcaactcc acctcgaccg ccggcagcgg ctgccgcacc tggcgctcgc
    19621 ccgcacgacc ccggcgaccc tccgctacac cgcgctgccc tggcactggc tcgccggtga
    19681 actcgcggtg cgggcccccg gcaccacgac cgtcgtcgcg gacctcgccg cggaccccga
    19741 cgtgtgggag cgcctcacca ccgcacccga cctcctgtcc ctggggcccg gaccgctcct
    19801 ctacgggcgg gtcgcccccg ccccccggcg cggtgaaccc ctggcccccg cctatctgcg
    19861 gtcatgggcg gaactctggc gttccggcgc gcgcctcccg tacgccacgc tccacgcgga
    19921 agccgccgcc cacgccgcct ccgccgtacc ggaggcggtc cttctcgcac ccgcgcccgc
    19981 tcccgccccg gtggtggacc aggacccgca ccccgcgatc ctggccgccg ccatggccgg
    20041 gcggcacggg gaggcggcgt cggtggcggc ggcctgggag cgcgaggccc tccgccgtca
    20101 cgggccccgg tccgcgcagg ccgtccactg gacggaggta cgggccgacc tcgcccgcct
    20161 cgccggggaa cccgcccgta gctgcgaact gtggctcgcc gccgccgagg cccggctcgc
    20221 actcggacag cggaccgacg accccgaggt cgaagcggcc gtggaccggg cccaccacca
    20281 gtgggaacag ctcggcgacc cggcgcgggc ccgcgcactc ggccctccgc tcatcgccct
    20341 gcggcaacgg gtcccgggcc gccagcccgg agccctggcc gcgctgaccc gccgcatgac
    20401 gggctgagtc ccggtcacgg cggactgggg agccgtaccg acagtcctgg tcgtccacga
    20461 cggaccgggg agccgcaccg gagtcctggt cgtccaccac ggaccgggag cgccggagtc
    20521 ctcctgatcg tccatgacgc gaacccacca ccccatgagc tcccgaagga cccgcgtgac
    20581 ctcgctcgcg ccgacgcccc cggaccggcc gtcgatcgaa gccgccctgg cggacgggcg
    20641 ggcgccccgc gacccgcccg cccgacaccc cctagtggtc gggaccgctc ccgcccggcg
    20701 ccgggaggac cacccggata ccgaactcgt aggtgccggt cgcctgcgcg atgccgatga
    20761 agagcagggc gaagtgctcc tggccccgcg ccgtcgcgat gccgcccagg tcgagcaccg
    20821 cgtcgtcgga ccagccgaga tcggtgacca ggccgcgcac caccttcttc gccgtggcgt
    20881 cctcaccgga gaggaacacc gtgccgggac ccgccaggga gtgcggcgcg accatcacct
    20941 tccggtcgac cgtcgcgagc gtcttcacca cccgcgtccc cgggaacgcc cgctggatct
    21001 cctcgccgag gctgaccacc ggatgcgaga gcgtcccgtc ctccaggaag ccgaccccga
    21061 cgtccaggat gatcctcccg gccagcgcgg gcgccccgac ggtggtcagg agggccacgg
    21121 actccgtgcc cggggtggcg ttcaccagca cctccgcgtg tgccgcggcg cccgccgaac
    21181 cgtcgatccg tacgcccgcc gcggtgagtt cctccagctc cgcccgcagc tcccggtcgt
    21241 cgggccgacg tgacccgatg accacctcat gaccggcccg cgcccacgcc gacgcgagcg
    21301 cccgtcctac gtttcccgtt ccgagaattc cgattcgcat gccgctcatc gtggccgcgc
    21361 gggccgcacc cgcacctcgg tcccggaacc cgacctcggt cggcccttcg gtctaggacc
    21421 gccgacgcgg ttccttgcga agccggcggt cctgcgatga tcggagttgt ggccatcccc
    21481 ccgcactccg ccccggcccc cgtgccggcc gccgcccccg agacgctcgg caccgggcgt
    21541 ctgctcctgc ggcccgtccg ggactccgac ctggacgccg tgacccgcct gtggaccgac
    21601 cccgaggtac ggcgccacct cggtggcccc gtcatcgagt cggtgatccg gatcaggcgg
    21661 cgccggatcg tcggggcgcc cggtttccac gccgtggtcc gggccgagga cggtgtcttc
    21721 ctcggcctcg tcacggtcga gccgggcgcg cggggcgggg agacggagct gtcgtaccag
    21781 ttcctgcccg agcactgggg gaggggctac gcacgggagg cggtcggtgc cgtcgtcgcg
    21841 aggaccctgg agggcacgcc gagcgtcgtc gccgtcaccc aggaggcgaa ccaccgctca
    21901 cgccggctcc tggaggccgt cggcctggag tacgccgagt ccttcgtgga gtgggacgcc
    21961 caccaggtgc tgtaccgccg ccaccgggcc tgaccccgac gtccgcccgg aggagcaccc
    22021 gccgtcagcg gggcggctcg cccgccgcga gccgggcaac cgcccgttcg agacgcgccg
    22081 tcctggtctt cgcggtgcgc gcctgcagca ggccgaggat caccaggtag cggtcggtct
    22141 tccccagcgc ctcgaaggcc tcggtggccc tcggctgcgc cgccagggcc gccgcgagg
//
