LOCUS       NZ_JAASJP010000007     21008 bp    DNA     linear   CON 27-SEP-2024
DEFINITION  Enterococcus faecalis strain K58 scaf_7, whole genome shotgun
            sequence.
ACCESSION   NZ_JAASJP010000007
VERSION     NZ_JAASJP010000007.1
KEYWORDS    WGS; RefSeq.
SOURCE      Enterococcus faecalis
  ORGANISM  Enterococcus faecalis
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 212906)
  AUTHORS   Lv,Q. and Li,S.
  TITLE     Detailed information of the 97 whole-genome sequenced gut bacterial
            strains
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 212906)
  AUTHORS   Lv,Q. and Li,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2020) College of Animal Science and Technology,
            Heilongjiang Bayi Agricultural University, Liming Street, Daqing
            163319, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. 3.2
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 100.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_019731285.1-RS_2024_09_27
            Annotation Date                   :: 09/27/2024 07:58:16
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,852
            CDSs (total)                      :: 2,794
            Genes (coding)                    :: 2,742
            CDSs (with protein)               :: 2,742
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 1 (5S, 16S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 2 (5S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 22 of 52
            Pseudo Genes (incomplete)         :: 35 of 52
            Pseudo Genes (internal stop)      :: 13 of 52
            Pseudo Genes (multiple problems)  :: 14 of 52
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 08:25:29
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 16698
            Orig. end                         :: 37706
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JAASJP010000007.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21008
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="darobactin"
                     /region_number="1"
                     /rules="((cds(PF04055 and (TIGR04085 or SPASM)) and
                     darobactin_precursor) or darobactin_rSAM)"
                     /tool="antismash"
     cand_cluster    1..21008
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="((cds(PF04055 and (TIGR04085 or SPASM))
                     and darobactin_precursor) or darobactin_rSAM)"
                     /kind="single"
                     /product="darobactin"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21008
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:11008](-)"
                     /cutoff="5000"
                     /detection_rule="((cds(PF04055 and (TIGR04085 or SPASM))
                     and darobactin_precursor) or darobactin_rSAM)"
                     /neighbourhood="10000"
                     /product="darobactin"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11008)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="((cds(PF04055 and (TIGR04085 or SPASM))
                     and darobactin_precursor) or darobactin_rSAM)"
                     /neighbourhood="10000"
                     /product="darobactin"
                     /protocluster_number="1"
     gene            496..1353
                     /locus_tag="HCH27_RS10200"
                     /old_locus_tag="HCH27_10190"
     CDS             496..1353
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1287: AraC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF014376.5"
                     /locus_tag="HCH27_RS10200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HCH27_10190"
                     /product="AraC family transcriptional regulator"
                     /protein_id="WP_087548465.1"
                     /transl_table=11
                     /translation="MEDFWYHNKSASAPISLSQCGYESYHSDSSIRNYIVQQKWIFHYV
                     LSGKGFLEVDTQHFELKEHDIFFFFQGQKVKYYTDKKAPWTLIWVGIQGDEISEFLKET
                     TLLNIHTANLTETMNKKIKNILLKIVCENRELINEPETVKELRNIASIYNFLYHIKKIF
                     FAPSLITNKPTQVNIIDYINTHYMNDISPKKLAQYFNISYSQLYKICISKFNSSPKKII
                     TNHRIRIAVDLLIDSDNTIKEIAQKIGYKDEFLFSKTFSKTLGYCPSKFRKLNKDQLKK
                     IRFK"
     gene            complement(2059..2301)
                     /locus_tag="HCH27_RS10205"
                     /old_locus_tag="HCH27_10195"
     CDS             complement(2059..2301)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313008.1"
                     /locus_tag="HCH27_RS10205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HCH27_10195"
                     /product="hypothetical protein"
                     /protein_id="WP_065535889.1"
                     /transl_table=11
                     /translation="MRKGIADIEKIRHILATQTSNRIARETGITKSTIEKLKSGERSVE
                     KLNLSYAIKLTEYAEKQVIPVIEIWGKTDINRGSD"
     misc_feature    complement(3182..3197)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.81"
                     /tool="antismash"
     gene            4189..4344
                     /locus_tag="HCH27_RS14445"
                     /old_locus_tag="HCH27_10200"
     CDS             4189..4344
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013753.5"
                     /locus_tag="HCH27_RS14445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HCH27_10200"
                     /product="transposase"
                     /protein_id="WP_376706349.1"
                     /transl_table=11
                     /translation="MARFHIVQHLNHSFNQFRIQIMNYFCASSSEDQKKYQQLKRHRKL
                     LLKRFR"
     gene            4479..4724
                     /locus_tag="HCH27_RS14450"
                     /old_locus_tag="HCH27_10205"
     CDS             4479..4724
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013753.5"
                     /locus_tag="HCH27_RS14450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HCH27_10205"
                     /product="transposase"
                     /protein_id="WP_087548463.1"
                     /transl_table=11
                     /translation="MILPYLELLEKFKIFSCYHSGIQNTFKSPLSNGVTERLSNKIKPI
                     KRITFSYRNFYNFKAFVYLQQGLISLKIKKYELYTF"
     misc_feature    5009..5022
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: medium, score: 20.91"
                     /tool="antismash"
     misc_feature    complement(5058..5072)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: medium, score: 23.81"
                     /tool="antismash"
     misc_feature    6367..6385
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: weak, score: 24.25"
                     /tool="antismash"
     gene            6410..6688
                     /locus_tag="HCH27_RS10220"
                     /old_locus_tag="HCH27_10210"
     CDS             6410..6688
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF022814.5"
                     /locus_tag="HCH27_RS10220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HCH27_10210"
                     /product="DUF3173 family protein"
                     /protein_id="WP_080476180.1"
                     /transl_table=11
                     /translation="MALSKAIQKHLCKYIFRNGENILKEIITKKELIIVGFSEYTSEKL
                     IKQSKQIMVKNGYPFYNNKRIGYVPKKVVESILGCKLELEETTYGKN"
     gene            6675..7883
                     /locus_tag="HCH27_RS10225"
                     /old_locus_tag="HCH27_10215"
     CDS             6675..7883
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1077: phage integrase
                     family protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140786.1"
                     /locus_tag="HCH27_RS10225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HCH27_10215"
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="WP_087548461.1"
                     /transl_table=11
                     /translation="MGKTKYPGVYVDNNGQFYYEAYLGRDKITRKKIRKKSRKNKQGKK
                     FTTARQAYKELTRIKHESLSTNGYANYDMTYNQYMDNVYIPFYKSEVEESTFYVRKKTL
                     ENIRDRFGTIKLREITIADVQFYRTWLLSKNGANYSQAYASLVFGMFRKTLDMAVEMQF
                     LEENISKRVKSIPKGKSIIPYWTKDDFEKVISQICIDDFYEHLCFVMLWIYFMTGIRVS
                     EGTALWWNDVDFKKKRLRIHHTLFIRSKKNWERKNYTKTAEGKRVISIDDDTILILKTW
                     KKRQAKMGIYDFVFSYDGLPMIKSTISRIVNRYATLANVPHIQAKGLRHSHASYLINEF
                     NVSVLILSKRMGHSSPEITLKHYSHMWAGIDETVAQIMSGNIKIHPATKTKINFKGNHV
                     IKK"
     gene            complement(8168..9523)
                     /locus_tag="HCH27_RS10230"
                     /old_locus_tag="HCH27_10220"
     CDS             complement(8168..9523)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010819693.1"
                     /locus_tag="HCH27_RS10230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HCH27_10220"
                     /product="PIN-like domain-containing protein"
                     /protein_id="WP_010819693.1"
                     /transl_table=11
                     /translation="MANLKELFPEFYQSKLDMKDLSSESENLLVLDTNYLLDIIQLPTT
                     VSKKYIEALEKVKENIYIPYLVALEFNFKKSSLKKGKIKKIRKYKNEIEQSVVNINKKI
                     NEIDLVDKEEKEIFTNELLTMTEDYLAELKKVIDSKVSSMITEEENELYERLISVIENK
                     VGNKYSQEWIDEIEKEGEERYKQNIPPGFNDSSKEDEIDSLRMYGDIKYCRKYGDLIIW
                     KDIIEYSKEYTKMGKKVVFITNDGKAKQKRDLLYKVDDFTVGPNIHLMNELYMESNKEL
                     HILNNLRFVQLVNDLSDVEMSKLKKSSEKMYRVKIPHDQIEEERIKLLKKSIENNEYEF
                     GISDDGYLFKKEKNHIDNLYNSTIEDIERKKLIKYINMINHGGNHDRSKEEFYKMYLLN
                     KLTESELKDYKQMELWDKDDRSNKMSYDSESRKFIFNFDDDLEDNFDNEENE"
     gene            complement(10001..11008)
                     /locus_tag="HCH27_RS10235"
                     /old_locus_tag="HCH27_10225"
     CDS             complement(10001..11008)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     darobactin: darobactin_rSAM"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     darobactin: TIGR04085"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     darobactin: PF04055"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     darobactin: SPASM"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PTHR43273"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) QueE"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002394592.1"
                     /locus_tag="HCH27_RS10235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HCH27_10225"
                     /product="radical SAM/SPASM domain-containing protein"
                     /protein_id="WP_260452317.1"
                     /sec_met_domain="PTHR43273 (E-value: 2e-39, bitscore:
                     129.1, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 1.1e-22, bitscore: 74.6,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 9.2e-16, bitscore: 51.9,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="QueE (E-value: 7.4e-13, bitscore: 41.9,
                     seeds: 32, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 2.7e-09, bitscore: 30.9,
                     seeds: 166, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 1.9e-10, bitscore:
                     34.5, seeds: 281, tool: rule-based-clusters)"
                     /sec_met_domain="darobactin_rSAM (E-value: 1.0, bitscore:
                     1.0, seeds: 0, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNSFELRSVYLEVGSLCNLKCKHCYNKSGSGMYRFSEDQILSIFK
                     EISKLKCQNVIISGGEPLLYKNLINLLRIGKQKYGLCIWLVTNGTMVDDYLAQRLSNVV
                     DYVQISIDGTTPEENDAVRGKGTFQKAIYAIELFEKYKIKTVVNFVITGKNTSKLAPFL
                     SALKSKNVSVISFKEIINIGRSKGEKPVSGEFFRSIVKELLLLMEELQDDNFEIKPPYV
                     SNSRCPLYFENNYTPTLEIRISYTGEVFLCQKFETEKVFSLGNVNVDLLTDIMQSEKYV
                     DLFSLIDVSTKFIKKCEGCFFTEMCFRECPATIISNGFFDYQDQLCDIRHFGMD"
     gene            complement(11011..11856)
                     /locus_tag="HCH27_RS10240"
                     /old_locus_tag="HCH27_10230"
     CDS             complement(11011..11856)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002394593.1"
                     /locus_tag="HCH27_RS10240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HCH27_10230"
                     /product="PqqD family protein"
                     /protein_id="WP_002394593.1"
                     /sec_met_domain="PF05402 (E-value: 1.9e-10, bitscore: 34.5,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLIQKRFLEFKPCLIENYLIYYRFEHGGYVTIKTIVNSQKTELVN
                     STYYYILTMCDGVNSVENIIDKIMAKYIGAPKSLIEKDVIKTIEKLSICGGLKLKDNPF
                     FVKESIHLSNELSISYDISACYSSLLKLILQEKGDCLRIFKNPFYDDLFVNSLILNRDF
                     ELNKSTIVLMIIDNLRKTNCGFMIWNIQNKNNVILQYYCRNKNIEVFDEKILKNGIALT
                     TKLLKQRSLTYKVFCIQNNLESQSLISNIKNLKFRHINSYKKEVRSQNVDEYQFNFGGI
                     "
     gene            complement(11877..12857)
                     /locus_tag="HCH27_RS10245"
                     /old_locus_tag="HCH27_10235"
     CDS             complement(11877..12857)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PTHR43273"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) QueE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF015983.5"
                     /locus_tag="HCH27_RS10245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HCH27_10235"
                     /product="radical SAM/SPASM domain-containing protein"
                     /protein_id="WP_010830586.1"
                     /sec_met_domain="PTHR43273 (E-value: 3.5e-39, bitscore:
                     128.3, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 1.7e-19, bitscore: 64.3,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="QueE (E-value: 8e-08, bitscore: 25.5,
                     seeds: 32, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 1.7e-11, bitscore: 38.1,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNNIVRGPININFDITNRCNLNCLHCYNSSGEGDFSFELSDNEVL
                     NIVDQIIEMKPYNVCICGGETLIRKRLVLKVLEKLTKANISCGMVTNGILLTEELAKSL
                     KKKGINNIQISLDGKKWAHNNLRNNKNAYDGAIRGLKLLSKYNIISGIAFSPTKWNISE
                     FDSVFSLAEELGVHEVRLQDLMPVGRAEKNLHILPSEKEYRQLKKEYNKKILENLNGKT
                     NVNVAWGDPIDHLLVFTESFSNSSYTDTICILSDGSITPSIYLPKTFGNLRKHTLSEYW
                     IGGLNQIWGSEHIISMVSKLTSVKQMTTPSNNTQSNRSTEFDILN"
     misc_feature    complement(12830..12850)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 24.09"
                     /tool="antismash"
     gene            complement(12892..13362)
                     /locus_tag="HCH27_RS10250"
                     /old_locus_tag="HCH27_10240"
     CDS             complement(12892..13362)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002394597.1"
                     /locus_tag="HCH27_RS10250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HCH27_10240"
                     /product="hypothetical protein"
                     /protein_id="WP_010819691.1"
                     /transl_table=11
                     /translation="MYKHVNEGDTGDLMLFLKTLSEEGGSSFFDNTNIMKMQVNSISLA
                     RYYLYKKEQEVIYDESKENFIGLFVENNYRNSASINFIFLKNDSQMKLQEMINYIKNEM
                     VSFLVKEVNKLVIDLDSNTEFFKVWENRILAVGFNKCTLAKESRLFTYELLL"
     gene            complement(13436..13624)
                     /locus_tag="HCH27_RS10255"
                     /old_locus_tag="HCH27_10245"
     CDS             complement(13436..13624)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002394598.1"
                     /locus_tag="HCH27_RS10255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HCH27_10245"
                     /product="hypothetical protein"
                     /protein_id="WP_002394598.1"
                     /transl_table=11
                     /translation="MNEQNFSEEQKKYQSPSSQNFYGSEIQPTSSTVFGIVMVFTVVAA
                     YWVVNSFKPCKCYGNIA"
     gene            13827..15419
                     /locus_tag="HCH27_RS10260"
                     /old_locus_tag="HCH27_10250"
     CDS             13827..15419
                     /EC_number="7.-.-.-"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002394599.1"
                     /locus_tag="HCH27_RS10260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HCH27_10250"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_002394599.1"
                     /transl_table=11
                     /translation="MLLFLSNYFKQAKKKILIFSILNMLIAFISAVVPLISGNFIDSLV
                     SSHDYQIIIKFIIILCLFVFAQLSLGYVVQVQEAVLQAHLTYNIQKDILNQLQKTQIYL
                     ISQYDLANLSQRISSDSSSISSFMISSGSSLLVCCLNFFFSTILLFIVKWEIALFILVF
                     LVLYILYFYKLQNNLTVKQKDVKNDFSYYFSQIFSQLKNLKNLKIFSLYNYYGISLFDS
                     YNKYIYSLKKFKIFSFRLTSGDTLLAFFAQIVIFIFGGVSVINGNMTIGIFSVLLSYFN
                     MMLNSIKYIPSLTSSYAEMFASYSRITELINLEKDNTGKLKYSDNNFLEIKNLTYKYPG
                     SNTYLFSKFNYSFQKGNIYCLKGRNGSGKTTLLDIISKLKFSYNGSIELNQRNIELFDT
                     KYYRDVCLSYMTQDAFVIKAGLKDNILSQNLSEKLSTLIQELGLEKYIDSNYNINTKIS
                     GGEKQKISFLRSITKPFNILLLDEPTNHLDFISKEILMKYLNNIKNDAIIIISSHDNFV
                     LERVDTIIDLNKS"
     misc_feature    15696..15711
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: medium, score: 25.8"
                     /tool="antismash"
     gene            17024..17320
                     /locus_tag="HCH27_RS10265"
                     /old_locus_tag="HCH27_10255"
     CDS             17024..17320
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002408190.1"
                     /locus_tag="HCH27_RS10265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HCH27_10255"
                     /product="hypothetical protein"
                     /protein_id="WP_010819690.1"
                     /transl_table=11
                     /translation="MSKETFLKYGFVVLFIGIFLLRAQKFISEPLSYLFSGILLLIVAY
                     LILVKKMNFFSSLLTITDQPSSTQQRLGQLSGLVSLLIGLLLVILSFIFFLQL"
     gene            17471..18016
                     /locus_tag="HCH27_RS10270"
                     /old_locus_tag="HCH27_10260"
     CDS             17471..18016
                     /EC_number="2.5.1.17"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002399092.1"
                     /locus_tag="HCH27_RS10270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HCH27_10260"
                     /product="ATP:cob(I)alamin adenosyltransferase"
                     /protein_id="WP_002385445.1"
                     /transl_table=11
                     /translation="MEKMYRSPYEAYPYLSSKPEDLRCDFELMTDELASMTGLLRGYVQ
                     QLDVPEQPALTEELAKICELIYHVNPTTRTKLTVTEEEIAWLLERVNAMNELTYEENRP
                     FVLPMGTICSSYAHILRAKAKDIVRLLYRMDYGGKKIDPQLYDVVNLLSGYFFMLALYL
                     NQLENGEEVPFVSRNYSI"
     gene            complement(18065..18853)
                     /locus_tag="HCH27_RS10275"
                     /old_locus_tag="HCH27_10265"
     CDS             complement(18065..18853)
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002379870.1"
                     /locus_tag="HCH27_RS10275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HCH27_10265"
                     /product="PhzF family phenazine biosynthesis protein"
                     /protein_id="WP_002379870.1"
                     /transl_table=11
                     /translation="MSYPYYIVDAFAEEVFKGNPAAVYVLEKWLPEAVMQNIAIENNLS
                     ETAFTVKEGQSYALRWFTPEREIDLCGHATLATAFVLFNYYSVAEETLHFTSQSGPLAV
                     TKKEEYYYLDFPYILPERIPILPEYEAALGTKIYEAYLGRDLFFVLKDEETVAKITPDF
                     SALKALDLGVGVIVTASGDSVDFVSRTFFPKLRINEDPVCGSAHANLIPYWGKRLNQTT
                     LSAYQVSPRGGFLTCEVKENRVIIGGTAKLFAKGEAYLFV"
     gene            complement(18855..19820)
                     /locus_tag="HCH27_RS10280"
                     /old_locus_tag="HCH27_10270"
     CDS             complement(18855..19820)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1158: ornithine cyclodeaminase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016630577.1"
                     /locus_tag="HCH27_RS10280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HCH27_10270"
                     /product="ornithine cyclodeaminase family protein"
                     /protein_id="WP_002359267.1"
                     /transl_table=11
                     /translation="MDIISYERVIQQLSFSEAIQVMKRCFAELQKGKISQSERHVEVLP
                     DGENQNLFALMPAYLGKNRFFGAKIITAFPENPQKNLASHLGQILLFDSSTGRPVAMMD
                     ANAITWLRTAAVSALATDYLAAPKAKSIALIGAGQQASSHLAALQSVRAIEKVFIYDRT
                     AERARKLIAKQQHNYPECTFIGCSSVQEAVQEAEIICTLTSSQDAFLEEKDVLPNAHIN
                     AIGTFTPTSRELTSDLVKNSQVFVDEYAAALKESGDLLIPISEGAFSAEKIVGSLGELV
                     TGKVKLKAEQKGRTIFDAVGLAVEDLCCAEYIYQKIQGEN"
     misc_feature    complement(20039..20054)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: medium, score: 24.91"
                     /tool="antismash"
     misc_feature    complement(20745..20759)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 23.01"
                     /tool="antismash"
     misc_feature    20963..20975
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 19.31"
                     /tool="antismash"
ORIGIN
        1 taataaatga cgacaatgca actagtcctg aagacaaagt atctgtttta tatattttgg
       61 caatatttac tcctaaacaa taaataaaga gcaaagctac tatcgaaatg ctacctttaa
      121 aaaccaaatt attaatatct acccaccatt gaaagaagga cgtaatcttt tgtaaattaa
      181 attgatcagg aatatcaacc aaaaaagcat tgattaacaa cgcaactgaa cctgtcatta
      241 ctacaggcat tgtccctata aaagaatctc ttaaagctac taaaaatcgt tgattcccaa
      301 ttttagtagc tataggtaaa actttattct gaatcgtatt cattatcttc tcactcatca
      361 cattcactcc ttcaaaaata attagaaagc gctatctaat tatagtatat aaattttttt
      421 gaccatttga acatgatact ttatacttaa aacatggtat tttcttcata attagttcta
      481 taaaggagga taacaatgga ggatttttgg tatcataata aatcagcttc tgctccaatt
      541 tccctttcac aatgcggata tgaatcttat cattccgact cttctattcg taattatata
      601 gttcagcaaa aatggatatt tcattatgtt ttatctggta agggattctt agaagtagac
      661 actcaacatt ttgaacttaa agaacacgat attttctttt tttttcaagg tcagaaagtg
      721 aaatattata cagataaaaa ggccccttgg acactgattt gggtaggtat acaaggtgat
      781 gagatctctg aatttttaaa agaaacaact ttattaaata tccatacagc taacttgact
      841 gagactatga ataaaaaaat aaaaaacata ctattgaaaa tagtatgtga gaatagagaa
      901 ctaattaatg aaccggaaac tgtaaaagaa ttaagaaata tagcgagtat atataatttt
      961 ttatatcata ttaaaaaaat tttttttgca ccttctttaa tcacaaataa accaactcaa
     1021 gttaacatta ttgactatat taatacccat tatatgaacg atatttctcc taaaaaatta
     1081 gctcaatatt ttaacataag ttacagtcag ctatataaaa tatgtatatc taaatttaac
     1141 tctagtccta aaaaaataat aactaatcat agaattagaa tcgccgtaga tttactaatt
     1201 gattccgata atacaattaa agaaatagct caaaaaattg gctacaaaga tgaattttta
     1261 ttttccaaaa ctttttctaa aactctaggt tactgtcctt ctaaatttag aaagcttaat
     1321 aaagatcagt taaaaaaaat aagatttaaa taaataatac atgctttttt atttttatgt
     1381 ttagagaaaa attatgtaaa aaattttttc atattcctaa gtctaaattt aagaactttg
     1441 aaatccaaaa ctattctgtt ttagatatgc attcaagata tctattaaca ataagagttg
     1501 aaaaaatact actattatct ctaaaggaga aggcaacgac ttttctacta ttattttttt
     1561 aaatgaagaa acaaaagttt tgtgaattac ttacaataga taaaactgtt tattgataat
     1621 aatcgaaaaa tatactttat aggaactata gcagttagtt tagtagaaat aaagtagaaa
     1681 tcttcttagt gaaatacttt agaagattcc tttttaattg aaaaagactt tttattaatc
     1741 cgttttatat ataatagacc agtacttatc ggataagttt tcattaaaag tttctctaag
     1801 tttattagct gaacggctaa aacactaata tcagagtcta ttgttttatc tatttcaatt
     1861 ttttcactgt ttaataagct actctacttt tcttctttca ttccgttgaa gttggagtac
     1921 attatctttt acagtataat tacactttga tttgactaca ataaaagtca aatcaagatc
     1981 gaggtcagca gagtcattat ctaaattatt ttttataaaa tagctttctt cgagaaattc
     2041 atatgtttat gtccataatt aatcacttcc tctatttata tcagtttttc cccagatttc
     2101 tataacagga attacttgtt tttcagcata ttctgttaat ttgattgcat aagaaagatt
     2161 aagtttttca actgaccgtt cgccactttt taatttttca atagtagact ttgtaattcc
     2221 tgtttctctg gcgattcggt tacttgtttg agtggctaaa atatgtcgta ttttttcaat
     2281 atctgctatt ccttttctca ttttttctcc tcgtatatta atattaccag atatattctg
     2341 actggttgtt cctttaaacc ttcttttgga cctaaacttg tagtagacaa aaataggtcg
     2401 tagttatttc cttaaatctt tttcttcctg aaaaagattt acgtctcttc tcttgcgata
     2461 atatataaat atgctagata gatcctggtt tatgaatgtc taaacaaggc tatattgtcc
     2521 aagagtagag aaagccccct ctatctatca aatcattgaa aatatctgat ttgatgtttt
     2581 ttctcagtat tgatattggt aagcaacacc ttaaaggtga attgatcgcc caacacagaa
     2641 atctgattgg aaaaaccatc cgtatctcca ctaccgaatc tagcagtgaa caccatcttg
     2701 ttttcttcaa taaacactca tcacttctag aaaacacctt gattgaaatg aaacccattt
     2761 tatctatcta cactttcgcg cataagatat actttcatac cactttttaa gccgatatga
     2821 tgaatacttt attaatcgcc caagtcattc gattggatcg atgttctgac ttaaaaagta
     2881 aaatttctgc ttgtttaaat cacttttttc ctgaatacga tcagattttt tctaatatgt
     2941 ttggttgtta ttctacacaa attttattaa attcttttat tccatgaatt agactagacg
     3001 ccaaacatct tacaaagacc attaatacat ctagtgagaa gagcttacga ataactcaga
     3061 aaaaaatgat gaaattgaaa gaagtagcac attcttttgg tatttcgatt gttctgatgt
     3121 cttcgagtta aagattcaaa tcatgataga acaaaatgct cgattcttaa atcaaaatca
     3181 ttgaaacaga aattcaagaa aacgtttcaa aacgagaaag cgaggaagtc aaatgaaacc
     3241 actattggta tagtaactag aacactcatg aaaattattt ttgctgttta gaaacaaaac
     3301 aaactttacg aagttcattt cctcgagaat atctcagaga aataaatttt catttgatta
     3361 ttggagattt atttggtgtg ttttcttaaa attccttttt cacttgacta attcatagct
     3421 agattttatg ttgttctaca atcagtatta tatcattttg aaacatatca tggtatgttt
     3481 tttttagaag aataaaaagg aaaatcattt gtagtaacac taatttaact gataaaaaaa
     3541 caacatcgat tattataagc agaaataatc ctttatacat ttgtagatta tagcagaaaa
     3601 agagattcta taatattttc tactaacact tttttcctgt ctttcaatta attaaaaagg
     3661 agctaccgtt gattgaattt agtcgcctaa aaataagccc ctcaaaccag agcatctcaa
     3721 tgaattatca tcatactaaa aaattacttg attaacatac tacacttata tttcgatgat
     3781 aattggttag aaaaaagacg ctacgctata aaggttttca aactcaaatt accaacggaa
     3841 aactaattac ttcgcctagc aaatgttaaa taacaaaaaa gtactttgct tcttatagaa
     3901 caatttaacg tatatcttat gcgaaacgac taaagattat caaccgaatt aaaaatgtat
     3961 atcctctgtt ttatgtatga ataagtttaa atccatcgtt gaagctatga gttttttcgt
     4021 gtgaacggaa taatcaataa gctgttcata attcttgaaa attagaggtt actcaagttc
     4081 acacaataat ttatacgccg cacgattgaa cttgaaatac cttatgatgg atataaatgc
     4141 tagctataaa caactgttag aaaagtattt cccgatgcgt aaatcatcat agctcggttt
     4201 catattgtac agcatctcaa tcatagcttt aatcaattcc gtattcaaat catgaattat
     4261 ttttgcgctt ctagttccga agatcaaaag aaataccagc agctgaaacg ccatcgcaaa
     4321 ctattactaa aaagattcag ataaactaaa accactctca tcggcgaact cctaagctat
     4381 gccaatgaat tacgacaagt ctaccaggtt tgtccaactt ttacgttact actttaataa
     4441 aagggactac aaatgttttc acgaaacact aaagaacatt gatccttcct tacctcgaac
     4501 ttttagaaaa attcaagatt ttctcttgtt atcactctgg tattcaaaat acttttaaaa
     4561 gccctttatc aaacggagta acagaaagac ttagcaataa aatcaagccg attaaacgta
     4621 tcacctttag ttatcgtaat ttttacaatt tcaaagcatt cgtttattta caacaagggc
     4681 tgatatcttt gaaaatcaaa aaatacgagc tctatacttt ctgatgtttg tatttttact
     4741 aacatctttt ttaattcaaa aaaagacacc tcaaaatcct gcaaaattaa agtcgctaat
     4801 cccattttaa agaaggatca agatatccta tactgaactt atcaaagaaa ccttaaatat
     4861 tttagaccta aatgttaaat ttaaagaaaa ttgtttgcga aaagaaaaaa taaacggata
     4921 aatttgtaaa gtttatacag gaaaattaat atacttctca gattcttatg aacattgtaa
     4981 aagtcacgcc gctattatgc gctaaaaagg aacgaacgtt cgattgttgc tgaatgaagt
     5041 cgcagaattc aaaatttatc tcgaattgag aaaacaatgt tttaaatatc atacgtgtca
     5101 acaaactttt gttgcagata caagtattac agaaaagcat tatttcatta atcaatcttt
     5161 caaatggacc attactacac gtttaaaaga aaatacctac atgacaggaa tcgctcgtca
     5221 aaaaatgttg ctgtttctcc tatttatcgt gtgcctaaat gcttctacca accgatgaat
     5281 ccttttaaga caactttatc aacggttctt cattttaatg aatttaaatc cattcgtcat
     5341 gtttccatcg tcatgagttt tatcatttta aatgggcaaa caagaaaatt attggatatt
     5401 gttggaaacc aactacttcc tttaatatta aaaaatcact ttctcccctt tttatttttt
     5461 gcaaatagaa aaaataagta acagattcat ctattttctc tctttctttt aaacaaaaaa
     5521 taaaatttaa ttacctgtaa ataaaaacta actagtatat ttttcaatac tattaaagta
     5581 atattctcta taaaaattca caacatattt atctttattt taaattatca taatactgaa
     5641 cttatggtac ttaatcaatt aatgatcaat attcccctta aattgaaaag tatgctattt
     5701 tcatagttta gttgacgcct ctcttgctgt aatatgtcat agccttcact ttttgagcta
     5761 tatctcatat attagtagtt tataaaaaca acaatcttct ataattattt attcaagcaa
     5821 tcataatatc aatttcccaa tatccaaaac gcgctctttc aattgcttct tttatccact
     5881 cactcataat tacttttccc atctttttca gatactttcc aaagcaaaat atttaacgag
     5941 aaaagtatct gtccaaatca tcgtctaaat atgtttttaa aatttatttc tattatctgt
     6001 gaaattacta aattgatagg taaaagcgca taaaccaata atttgagtgt ctaaaacaat
     6061 tagttctatt tgtcctaata caatctaaaa cacattaatc aatggaaatc ctaaagaaag
     6121 cttacaataa atctaaatat atatagtact tataaaaaag aaagaaattc atatgtcatt
     6181 tttgttcatt aatttgttgt tattagtaga gacttgacct ttgaaaatta aatagttttt
     6241 gaattacgtt tgctattgta tgagcttgat aatagtacgc catgacaatt tgagcgataa
     6301 catactaatt atttctcttg aactaggtat tcaagatgcc atgactataa tagcctataa
     6361 tgatacttcc gtgaggctcg ccataaatta ggggagaggt gaaattccta tggctttatc
     6421 taaagcgatt caaaaacatc tgtgcaaata tattttcaga aacggagaaa acattttgaa
     6481 agagattatt acaaaaaaag aattaataat tgtgggtttt tctgaatata cttcagaaaa
     6541 acttatcaaa caatctaaac aaattatggt aaaaaatggt tatccattct ataataataa
     6601 acgtataggc tatgtaccaa aaaaagttgt tgaatcaatt ctaggatgca aacttgaatt
     6661 ggaggaaaca acatatggga aaaactaagt atcctggtgt atatgtagat aacaatggac
     6721 aattttatta cgaagcatat ttaggaagag ataaaataac taggaaaaaa ataagaaaga
     6781 aaagtaggaa aaataaacaa gggaaaaaat tcaccacagc acgacaagca tataaagagt
     6841 taacccgaat aaaacatgag tcactttcaa ctaatggata tgcaaattat gatatgacat
     6901 ataatcaata tatggataat gtatacattc ctttttacaa atctgaagtt gaggaaagta
     6961 ctttttatgt acgaaaaaaa actttggaaa atattcgcga tcgatttgga actattaaac
     7021 ttcgagaaat tactattgca gacgtgcagt tttatagaac ttggttgcta tctaaaaatg
     7081 gggctaacta ttcacaagcc tacgctagtt tagtatttgg tatgtttaga aaaaccctag
     7141 atatggctgt agaaatgcaa tttcttgaag aaaatatttc aaaacgtgta aaatctattc
     7201 caaaaggcaa atctattatt ccttattgga caaaagatga tttcgaaaaa gtaatatcac
     7261 aaatttgcat agatgatttt tatgaacatc tttgctttgt aatgttatgg atctatttca
     7321 tgacaggtat aagagttagt gaaggtaccg ctctatggtg gaatgatgta gattttaaga
     7381 aaaaaagatt aagaatccac catactttat ttatacgtag taaaaagaac tgggaacgaa
     7441 aaaactatac aaaaactgct gaaggtaaaa gggttatttc tattgatgat gataccatac
     7501 tgattttaaa aacatggaaa aaaagacagg ctaaaatggg gatatatgat tttgttttca
     7561 gctatgacgg cttacctatg ataaaatcaa caatatctcg cattgttaat cgatatgcta
     7621 cgcttgcaaa tgtgccccat atccaagcaa agggattacg tcattcacac gcatcctatt
     7681 taattaacga gtttaatgtt tctgtcttaa ttttatcaaa acgtatgggc cattctagcc
     7741 cagaaattac tctaaaacac tattcacaca tgtgggctgg aattgatgag actgtagcac
     7801 aaataatgtc tggtaatatt aaaattcatc cagctacaaa aacaaaaata aattttaagg
     7861 gaaatcatgt aataaaaaaa taatttccac caaaattcca ccatattttt tcgatatgga
     7921 aaaaatctta ttttacaaag gtttcgtaca gcctgcatac ttggagtggg aataaataat
     7981 gaaaccgtga aacctttgat attagagggt ttcacggtta ttttttattt tgtgcaacca
     8041 atacattcta ggtaaattac tttttccctt cacattgctt tactaataaa atactgcaga
     8101 aaaaagactt attcaaattg taaatctaat taaaataagt ctttgttatt atatattaat
     8161 ttttcaatta ctcgttttct tcattgtcaa aattatcttc taaatcatca tcaaaattaa
     8221 aaatgaactt tctagattca ctatcataag acattttatt cgaacggtca tctttatccc
     8281 aaagttccat ttgcttataa tcttttagtt cagattcggt taatttgttt aataaataca
     8341 ttttataaaa ttcttcttta cttctgtcat gatttccgcc atggtttatc atattgatat
     8401 attttattaa tttttttcgt tctatatctt caatagtaga gttgtataaa ttgtctatat
     8461 gattcttttc ctttttaaat aaatatccat catcagaaat tccaaattca tactcattat
     8521 tttctatact ttttttcagt agtttaattc gttcttcctc tatctgatca tgaggaattt
     8581 tcactctata cattttttcg gaagactttt tcaacttact catctctaca tcacttaagt
     8641 cattcactaa ctggacaaat ctcaaattat ttaaaatatg aagttcttta ttggattcca
     8701 tgtataattc attcattaaa tggatattag gtccaactgt aaaatcatca actttgtaca
     8761 acaaatctct tttctgttta gctttaccgt catttgtaat aaaaacaact ttttttccca
     8821 ttttcgtata ttcttttgaa tactcaataa tatctttcca tattataaga tcaccatatt
     8881 tcctacaata ttttatatca ccatacattc taagtgaatc gatttcgtct tcttttgaag
     8941 agtcattaaa cccaggggga atattttgct tgtatctctc ctctccctcc ttctctattt
     9001 catctatcca ctcttgacta tatttattac ctactttatt ttcaattaca gaaataagtc
     9061 tttcatataa ttcgttttct tcctccgtaa tcatcgaaga taccttacta tctattactt
     9121 tttttaattc agctaagtaa tcttctgtca ttgttagtag ctcattagta aaaatttctt
     9181 tttcctcttt atctactaaa tcaatttcat tgattttttt atttatattt acaactgatt
     9241 gctctatctc atttttatac tttctaatct ttttaatttt tccttttttc aaactactct
     9301 ttttaaaatt gaactccaga gccactaaat aaggtatata aatattttct tttacttttt
     9361 ccaacgcttc tatgtatttc tttgaaacag ttgtaggtaa ttgaattata tctaaaagat
     9421 aatttgtatc tagtactaat aaattctcac tttcactgct caaatctttc atatctaatt
     9481 tagattgata aaactctgga aaaagctctt tcaaatttgc cattaattat ccctcttatt
     9541 aacaataatt ttatatcttg aatattcttt atacaataat attgtaacat atttattaat
     9601 ataaaataga atacaatagc tttaacatgg ttattctaac ttaaaaaatt tgcaaccaat
     9661 agagttggct taaaaaggta aatcatcatc actaaaactt atttttacta catctactgc
     9721 tcctaaccta gttcttaagt tttctaatat tatttttttc ttttgcttac tactgtatta
     9781 ggaaaaagac ctaacataat atagatgaat accgcttaca aacctacact ttttaactta
     9841 tgaaatgctt ggttctcata aaaaatgata tggttcccta gtattttcct accgaaaaaa
     9901 tccttgtctg actaatgctt gacaaggatt tttttgcaat tctccttata attcgtctgt
     9961 aaaaaatata tcttaagatt taaactgcta gttaaaataa tcaatccatt ccaaaatgtc
    10021 gtatatcaca tagttgatct tgataatcga aaaaaccatt tgaaattatt gtagctggac
    10081 actcccgaaa acacatttct gtaaaaaaac agccttcaca tttttttatg aattttgttg
    10141 aaacatcaat caagctaaat aaatcaacat atttctctga ttgcataata tcagttagta
    10201 gatcaacgtt cacatttcct aaactaaata ctttttctgt ttcaaatttt tggcaaagaa
    10261 atacttcgcc ggtataacta attcgaatct ctagagtagg agtataatta ttttcaaaat
    10321 ataacggaca cctactgttg gaaacatatg gtggtttgat ctcaaaattg tcatcttgca
    10381 attcttccat gagaagcaaa agctctttca ctatacttct aaaaaattct cccgaaacag
    10441 gtttctctcc cttggacctt ccgatattga ttatttcttt aaaagatatc actgaaacat
    10501 ttttagattt aagtgcactt aaaaaaggag ctagcttact cgtatttttc ccagttatca
    10561 caaaatttac gactgtttta attttatatt tttcgaatag ttcaattgcg tagatagctt
    10621 tttgaaaagt accttttccc cttacagcat cgttttcttc tggcgttgtt ccgtcaatac
    10681 taatctgaac ataatctacg acattactca acctctgggc aaggtaatca tctaccatag
    10741 ttccattcgt tactaaccaa atgcataaac catatttttg ctttcctatt cttagcaagt
    10801 ttattaaatt tttataaagt aacggctctc ctccagagat aattacattt tgacatttca
    10861 atttcgatat ttctttaaat attgatagaa tctgatcttc gctaaaacga tacattccac
    10921 taccagattt gttgtagcaa tgcttacatt ttagattgca taacgacccc acttctaagt
    10981 atacactcct tagttcaaaa gaattcaagt tcaaatacct ccaaaattaa attggtactc
    11041 atcaacattt tgacttctaa cttctttttt atatgaatta atatgtcgaa atttcaaatt
    11101 tttaatatta ctaatcagac tttgactttc taaattattt tgtatacaga acactttgta
    11161 tgttaacgac ctctgtttta gtagctttgt agtcaaagca atcccatttt ttaaaatttt
    11221 ttcatcgaat acttcaatat ttttatttct gcaataatat tgaagtatta cattgttttt
    11281 attctgaata ttccaaatca tgaacccaca atttgtcttc ctcaagttat ctattatcat
    11341 taaaacaata gtagatttat ttagttcaaa atcacgattt agaatcaaac tatttacaaa
    11401 caaatcatca taaaatggat ttttaaatat tctcaaacaa tccccctttt cttgtaaaat
    11461 aagttttaac aatgatgaat agcaagcact tatatcatag gatatcgaca attcatttga
    11521 taaatgtatg ctttccttca caaaaaaagg attatcttta agttttaaac caccacatat
    11581 tgataacttt tcaatagttt taattacgtc tttttcaatt aaagacttag gggctcctat
    11641 atattttgcc attattttat ctataatatt ttcaacacta ttcactccat cacacattgt
    11701 taaaatataa tagtaagtag agtttactaa ctcagtcttc tgagaattga caatagtttt
    11761 aatcgttaca tacccaccat gttcaaaccg ataatagata agataatttt caatcaaaca
    11821 aggtttaaac tctaaaaatc ttttttgtat taacatttta ccaccctatt ctttacttag
    11881 tttaatatat caaactcggt tgaacggtta ctttgtgtat tattacttgg tgtagtcatc
    11941 tgttttactg atgtaagttt tgaaaccata gatataatat gttctgaacc ccatatttga
    12001 tttagccccc caatccagta ttctgacaga gtgtgctttc tcaaatttcc aaaagtcttt
    12061 ggtaaatata tagatggcgt aattgaccca tccgataata tacaaatagt atccgtatat
    12121 gacgaattag aaaaactctc cgtaaatact aacaagtgat cgattggatc accccaagca
    12181 acattaacat tagttttccc gtttaaattt tccaatattt ttttattgta ttcttttttt
    12241 aactgtctat actctttttc agaaggtaaa atgtgtaaat ttttttcagc tctaccgact
    12301 ggcattaaat cttgtagcct aacttcatgc actcccaact cttctgcaag agaaaagaca
    12361 ctatcaaact cagatatatt ccacttagta ggagaaaaag caataccaga aataatatta
    12421 tatttactta ataactttaa ccctctaatc gctccatcat atgcattttt attattacgc
    12481 aaattattat gtgcccattt ttttccatca agactaattt gtatattatt tatccccttt
    12541 ttctttaatg acttagccaa ctcttctgtt aacaatattc catttgttac catgccacaa
    12601 ctaatattag ctttggtcag tttttctaag actttcaaaa ctaacctttt cctaattaaa
    12661 gtttcaccac cacaaataca tacattgtag ggcttcatct ctatgatttg atcaacaata
    12721 tttaacacct cattatcgga aagttcaaaa gagaaatctc cttccccact actattgtag
    12781 caatgtaggc aatttaaatt acatctattc gtaatatcaa aattaatatt tatcggccct
    12841 ctgactatat tattcatata actactcctt ccatccctat ttataaatta gtcaaagcaa
    12901 taattcatac gtaaataacc tactttcttt ggctaacgta catttattga atcccacagc
    12961 taaaatacga ttttcccaca ctttaaaaaa ttcagtattt gagtctaaat caataactaa
    13021 cttatttact tcttttacta aaaatgatac catttcattt tttatataat ttatcatttc
    13081 ctgtaatttc atttgagagt catttttcaa aaaaataaaa tttatactag ctgaattcct
    13141 ataattattc tcaacaaata atcctataaa gttctctttt gattcatcat aaataacttc
    13201 ttgctctttt ttatacaaat aataccgagc taagctgata ctgttaacct gcattttcat
    13261 aatatttgtg ttatcaaaga aagatgaacc accctcttcg gaaagcgttt tcaaaaaaag
    13321 catcaaatct cctgtatcgc cttcattaac atgtttatac acaatagtca ctccttccaa
    13381 attaaaatag aaaaagtaaa acaatttttt gctttacttt ttctgaaact gagtgctacg
    13441 caatattacc atagcacttg catggcttga acgagtttac aacccagtaa gctgcgacaa
    13501 ctgtaaatac cattacaata ccaaaaactg ttgaacttgt cggttggatt tcagaaccat
    13561 aaaaattttg tgaactggga ctctgatatt ttttttgttc ttctgaaaaa ttttgctcat
    13621 tcatattctc tcctcctttc caatactaat ctatataacc catagtcaac gccatttaca
    13681 cattcctctt gacaatggtc atatttctaa agctatgtgc taagtatacc ataactcctc
    13741 ttgtataaaa aatttttttt atcaataaca aataatttgg tgcttttgat ttaaaatatg
    13801 gtacaatgag ctaaaaggag aaaatcatgt tattatttct aagcaactac tttaaacagg
    13861 caaaaaaaaa gattctaatt tttagcatat taaatatgtt aatcgctttc atatcagctg
    13921 ttgttccgct tatttcgggc aatttcatag attcattagt ttcttcgcat gattatcaaa
    13981 ttataataaa atttatcata atactatgtt tatttgtatt tgcacaattg tcacttggat
    14041 atgttgtcca agttcaagaa gccgttttac aagctcactt gacttataac atacaaaaag
    14101 acattctaaa tcaacttcag aaaactcaaa tttatttaat ttcccaatac gatttagcta
    14161 acttaagtca aagaatatca agtgattctt cttcaatatc atcatttatg atatcttcgg
    14221 gaagttcgtt attagtttgt tgccttaatt tcttcttctc aacaattctt ttatttatcg
    14281 taaaatggga gattgcatta tttattttag tattcttagt attgtatata ctatactttt
    14341 acaaattaca aaataattta acagtgaaac agaaggatgt taaaaatgat tttagctatt
    14401 atttctcaca aatcttttct cagctcaaaa atttaaaaaa tttaaaaatt ttttctttgt
    14461 ataattatta tggaatcagc ttatttgact cctataacaa atatatatat tctttaaaaa
    14521 aatttaaaat cttttctttt aggctcactt caggtgatac cttgttagca ttctttgctc
    14581 aaatagtaat tttcatcttt gggggagtat cagtaataaa tggaaatatg acaattggta
    14641 tattctcagt tttactatca tatttcaata tgatgctcaa ctcaataaaa tatattccat
    14701 cattaacatc gtcctacgcc gaaatgtttg cctcatattc taggattact gaattaatta
    14761 atttagaaaa agataatact ggaaaattaa aatattcaga taataatttt cttgaaataa
    14821 aaaatttaac ctataaatat ccaggctcca acacttattt attttcaaaa tttaattatt
    14881 ctttccaaaa aggcaatatt tattgtttaa agggtaggaa tggtagcgga aaaacaaccc
    14941 tactggatat tatttctaag ctaaaatttt cgtataatgg ttccatagaa ttaaatcagc
    15001 gaaatatcga attattcgat acaaaatatt atcgtgacgt atgtctatca tacatgactc
    15061 aagatgcttt tgttattaaa gctggcttaa aggataacat attatcgcaa aatctctctg
    15121 aaaagttaag tactttaata caagaactcg gcttggaaaa gtatattgat tctaactata
    15181 acataaatac aaaaatttct ggtggagaaa aacagaaaat ctctttctta agaagcatca
    15241 caaaaccatt taatattctc ttgctagatg aaccaacaaa tcacttggat tttataagta
    15301 aggaaatact tatgaagtat ttaaataata taaagaatga tgctattatt attatctcga
    15361 gtcacgataa ttttgtgttg gaacgagtag acaccatcat agatttaaat aaatcctaac
    15421 atggaaagaa ggtaaaagtt aatgttaatt attaacatga taaaatcaac ttatgtaaac
    15481 caaataccta tattgatatt tataattgga ttgattgtat ttgccctgtc aaccaaaacc
    15541 ccgcacggag gaattgcata cagaggatta gcatattaca tatacggaaa acgagtctgg
    15601 tacttttcta ataaattagt aggtactttt ctaatggttg tatcaataat aacccttcta
    15661 tgctttaaag ttttatcaat gtccgaaaac acaaaaataa taattattat cctatcatgt
    15721 ttcatatgcc taattgtttc agatatcgta acaattctat ctataaagaa aggaaggcta
    15781 taataagttc attcttaact ttctttacta ttgatagcct atccactata taataagcat
    15841 ttttatttta atatttccca actttgttta accagtacaa attagttaaa gcctctaact
    15901 tttcttaagt aatgtaacca gttcttactc gattttaaaa ctttaaattg ttaaatatag
    15961 gaggaataaa tgatgaacaa gattcttaaa attttattaa ttatttttgt tattttaata
    16021 gtagtcattt ttctgcctac tattatattt ttcataatta aatagaaagg aggaatttga
    16081 aatgaattgg ttaaatttta gtgaaccttc actgcgtggc aattgttcag gtttaacttg
    16141 cggaattaaa acttgtatct cagtttcttg tccaaataat gggggttgcg catggagatg
    16201 gtgttggaat aaatcttgtt atatcaatct ttaaacaata ggaaaggagc atatgaatat
    16261 gaattggtta aaagactata acgaaattaa acctagaggt gcatgtgtca taagagtttg
    16321 tactcagtat aatggttgta accctctgta ctggtgttgg agattagaag gtaactaact
    16381 gaaagagagg tgttttgtta atgatttggc tttcgcaaaa atcaatagaa cctagatggt
    16441 gtttcttccg taccgcatgt cctagaaaac aaaatgatac ttgtataatt catataactt
    16501 aaatgggaat tgtgttgttc atagtttgaa tagtaacaat atgtttttaa tcacaaaccc
    16561 ttaatacaag tccgaatgaa aagtttcttt ataatcaact aatttttggt gataaaatta
    16621 agtttctacg aaataattat tatgtaatta ttggaaaagc cctattacca aaatcattac
    16681 tgatgttgaa atattttatt ttataaaacc taaatatcta aagacttatt taaccttagt
    16741 tgataatatt ctaaatgaac atgcctattt taaattactt tacatctgca taaatatcac
    16801 ctctcctatt accaaagttg ttggcttttg ggagggaata acaatcaacc cgctagaaaa
    16861 cctataaatt aggttttcta gcgggttttc ttttgtgtta tcacactttc ctcccaccat
    16921 tctccgtttt tcctttgctc caccgccctc aaagtcctat aatttaatca taagaataat
    16981 ggctattaat aaaatttatc aataaaaagg aagcgatttc aacatgtcaa aagaaacttt
    17041 tcttaagtat ggttttgttg tcctcttcat aggaattttt ttacttcgtg cccaaaaatt
    17101 tatttctgag cccctttcgt accttttttc gggtattctt ttgcttattg ttgcgtattt
    17161 aatactcgtg aaaaaaatga actttttctc aagtttgctc acaattaccg accagccttc
    17221 ttctacccaa caacgattag gtcaactttc tggtcttgtc agtttattga ttggtttact
    17281 tctggtaatt cttagcttca ttttctttct ccaactttga ttcccccttg actctccctt
    17341 cactcttggc tatgattacc ttagcaagta caatggtgta ctgtgaacag tcgagcaacg
    17401 gcgctcaaaa agattggctt tcgtgcattc tttttgaggg ctttttattt ttagaaagta
    17461 gggaaattga atggaaaaaa tgtaccgcag tccgtatgaa gcgtacccgt atctatcttc
    17521 taaaccagaa gatttacgat gtgattttga attaatgact gatgaattgg cctcgatgac
    17581 aggtcttcta cgaggatacg tgcaacaatt agacgtccct gaacagcctg cactaacaga
    17641 agaactagcc aaaatttgcg agttaatcta ccatgtcaat ccaacgaccc gaacaaaatt
    17701 aacagtcaca gaggaagaaa tagcatggct tttggaacgt gtcaatgcta tgaatgaact
    17761 gacatacgaa gaaaatcgtc cttttgtttt accgatgggc acaatctgtt cctcttatgc
    17821 acacatttta agagccaaag ccaaagatat tgttcgttta ctttatcgca tggactatgg
    17881 tggtaaaaaa attgatccgc agctgtatga tgtagtcaac ttactctcag gttacttttt
    17941 catgttagct ttgtatctaa atcagctcga aaatggtgaa gaagttccct ttgtttctcg
    18001 caactattct atttaaaaag tacaccgacc gctaacgacg aattgctagc ggtcggtgta
    18061 ctttttatac aaacaagtaa gcttctcctt ttgcaaatag tttagcagta ccaccaataa
    18121 tgactcgatt ttctttcact tcacaagtta aaaagccgcc tcttggggac acttgatagg
    18181 ccgaaagggt cgtttgattg agccgttttc cccaataagg aattaaattg gcgtgcgcag
    18241 aaccacaaac tgggtcttcg ttaattctta gtttcgggaa aaaagttcgt gaaacaaaat
    18301 ccaccgagtc tcctgatgcc gttacaatga ctcctactcc taaatccaat gcttttaatg
    18361 cagaaaaatc tggtgtgatt tttgccactg tctcttcgtc ttttaagaca aaaaataaat
    18421 cgcgacccaa ataagcttca taaattttcg tgcctaaagc ggcttcatac tctggcaaaa
    18481 ttggaatcct ttccggtagg atataaggaa aatctagata atagtattcc tcttttttgg
    18541 tcactgcgag cggtccactt tgactagtaa aatggagtgt ttcttccgca acggaataat
    18601 agttaaataa cacaaaagcc gtcgctaatg tagcatgtcc acagagatcg atttctcgtt
    18661 ccggcgtaaa ccagcgcagg gcgtaacttt gtccctcctt gaccgtaaaa gcagtctctg
    18721 acaaattatt ttcaatcgca atgttttgca tcaccgcttc tggcaaccat ttttccaaaa
    18781 cataaacagc ggcgggattg cctttaaaaa cttcctccgc aaaagcatcg acaatataat
    18841 agggataact cattttaatt ctctccttgt attttttgat aaatgtattc cgcgcaacac
    18901 aaatcctcaa ctgctaagcc aaccgcatca aaaatcgtgc ggcctttctg ctccgccttt
    18961 agtttaactt tgccagtgac taattcgccg agagaaccta caattttttc agctgaaaag
    19021 gcaccttctg aaatcggaat taaaagatcc ccgctttctt ttaatgcagc cgcgtactca
    19081 tctacaaaca cttgactgtt tttaacaagg tcgcttgtta attctctgga agtcggcgtg
    19141 aatgtgccaa tcgcattgat atgggcattc ggcaaaacgt ctttttcttc taaaaatgcg
    19201 tcctgactgg aagttagtgt acagataatt tccgcttcct ggacggcttc ttggacagaa
    19261 gaacaaccaa taaaggtaca ttcggggtaa ttgtgctgtt gcttagcgat taattttcgt
    19321 gcgcgttctg ctgtgcggtc atatataaaa accttttcaa tcgcccgaac gctttgtagc
    19381 gctgcgagat gagatgaagc ttgttgacct gcaccaatca aagcgatact ttttgccttt
    19441 ggagctgcta aataatcggt tgccaaagca gaaacagctg ccgtgcgaag ccacgtaatc
    19501 gcattggcgt ccatcatcgc aactggtctt ccagtagaac tatcaaacaa taaaatttga
    19561 ccaagatgtg aggccaaatt tttttgtgga ttttctggaa aagctgtaat gatttttgcc
    19621 ccaaaaaagc gattttttcc taagtaagca ggcattaatg caaaaagatt ctgattttcc
    19681 ccatctggta aaacctctac atggcgctca ctttgcgaaa tttttccttt ttgcaactct
    19741 gcaaagcaac gtttcatcac ttgaattgct tcggaaaacg acaattgttg aatgaccctc
    19801 tcataagaaa taatgtccat ctgaattcct ccctttgcgc tatcataaac cagacaaaca
    19861 atacactcaa tgttataatt gtatggaata caattttata gaaaggaagt tcccctcatg
    19921 ccgattaatt cctatgagaa ctatgcgttg tcatggcgcc ctgttaaaga acgtttaaca
    19981 agaccttatt accaatcatt ggttcaacaa ttagaagcgg atatcttatc tggtgcgctt
    20041 caaaaaaatg tgaaattgcc ttcgcaaaga gaattagctg attacttgga tctgaatttc
    20101 acgacgattg gtcaagccta taaacacgct atggaaaaag gcttacttta taccaacatc
    20161 ggtagcggca ctttcgtttc tcccaacgcg tttcactcaa ttacaatctc taccaaccaa
    20221 gtagcggacc atctaattga tttagggctg gttagttcct ttgatatgtg taatcagcgg
    20281 attttacctt ttattgaatc cgttagtaaa aatgcggccc ttaacagttt gctaaattat
    20341 cgcgatcctt taggtacgca ctttcaacga gcaaccgctg ccgaatggct tcagacacaa
    20401 ggcgttcgga ccaatgccga agaagttgcc attgtatctg gtgtccagaa tgggctggcc
    20461 gtgacgttag ccgccgcttt ttctccaggt cagcggattg ccgtagatcg atacacgtat
    20521 tcaaatttta ttgaactcgc ccagctttat catttagaaa tcgtcccgat tggctatgat
    20581 tccgagggga tggacccaga gcatttactg caagaatgca aaaagaaaaa aatacacggt
    20641 attttcttaa tgcccgcatg taataacccg attggtttcc aaatgtctag cgcccgccga
    20701 atgactttag ctgaaatcat tcagcaagaa cacttatggg taattgaaga tgacattcat
    20761 tcttttttaa caacttatgc acagcaagca gttttaccaa cgtttcaaga actcttacct
    20821 caacaaacga tttacttagc ggggatgaca aagtttgtct gtacaggctt acgcattgcg
    20881 taccttgttt tccctccgct tcttcgccaa gaaatagagc gtgcgatttt taacattaac
    20941 gttaaaactt ctggctttga tgctgaaatt gtcacccaag tcttacgctc accagttgca
    21001 gaagaatt
//
