LOCUS       NZ_AP024565            45940 bp    DNA     circular CON 26-SEP-2024
DEFINITION  Microcystis aeruginosa strain NIES-88 chromosome, complete genome.
ACCESSION   NZ_AP024565
VERSION     NZ_AP024565.1
KEYWORDS    RefSeq.
SOURCE      Microcystis aeruginosa
  ORGANISM  Microcystis aeruginosa
            Bacteria; Cyanobacteriota; Cyanophyceae; Oscillatoriophycideae;
            Chroococcales; Microcystaceae; Microcystis.
REFERENCE   1
  AUTHORS   Phan,C.-S., Matsuda,K., Balloo,N., Wakimoto,T. and Okino,T.
  TITLE     Argicyclamide A-C unveil enzymatic basis for guanidine
            bis-prenylation
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 5478552)
  AUTHORS   Matsuda,K. and Wakimoto,T.
  TITLE     Direct Submission
  JOURNAL   Submitted (16-APR-2021) Contact:Kenichi Matsuda Hokkaido University,
            Graduate school of phrmaceutical sciences; Kita 12, Nishi 6,
            Kita-ku, Sapporo, Hokkaido 060-0812, Japan URL
            :https://www.pharm.hokudai.ac.jp/tennen/index.html
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Unicycler v. 0.4.8
            Genome Coverage                   :: 87x
            Sequencing Technology             :: DNBSEQ; Oxford Nanopore
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_019704275.1-RS_2024_09_26
            Annotation Date                   :: 09/26/2024 11:16:24
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,602
            CDSs (total)                      :: 5,550
            Genes (coding)                    :: 5,071
            CDSs (with protein)               :: 5,071
            Genes (RNA)                       :: 52
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 479
            CDSs (without protein)            :: 479
            Pseudo Genes (ambiguous residues) :: 0 of 479
            Pseudo Genes (frameshifted)       :: 110 of 479
            Pseudo Genes (incomplete)         :: 380 of 479
            Pseudo Genes (internal stop)      :: 101 of 479
            Pseudo Genes (multiple problems)  :: 91 of 479
            CRISPR Arrays                     :: 3
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 14:54:59
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 5139240
            Orig. end                         :: 5185180
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            AP024565.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Annotated at DFAST https://dfast.nig.ac.jp/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..45940
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /contig_edge="False"
                     /product="T1PKS"
                     /product="terpene"
                     /region_number="12"
                     /rules="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or
                     hyb_KS or itr_KS or tra_KS))"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..45940
                     /SMILES="CC(=O)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds(PKS_AT and (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS))"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="neighbouring"
                     /product="T1PKS"
                     /product="terpene"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    1..45940
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="False"
                     /core_location="[20000:25940](+)"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      20001..25940
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
     misc_feature    complement(110..124)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: weak, score: 16.89"
                     /tool="antismash"
     gene            complement(858..3785)
                     /locus_tag="LC603172_RS25765"
                     /old_locus_tag="MAN88_50020"
     CDS             complement(858..3785)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1122: ATP-dependent
                     RNA helicase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008200667.1"
                     /locus_tag="LC603172_RS25765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MAN88_50020"
                     /product="RNA helicase"
                     /protein_id="WP_061433192.1"
                     /transl_table=11
                     /translation="MKESLNPTSLNLKTIFPFKLDDFQHSAIAALAAGKSVVVCAPTGS
                     GKTLIGEYAIYRALERGKRVFYTTPLKALSNQKFRDFQEKFGRTPTDGDEDSPLLFAEV
                     GLITGDVVINPSALIVVMTTEIFRNMLYKTPIGQVGTSLENVETLVLDECHYISDRGRG
                     TVWEESIIYCPPSIQLVALSATIGNPGELTDWINWVRQLPQPGDNQQTSSCDLINSDFR
                     PVPLRFYFANKEGLFPLLDPKQSKVNPKLRSKVGHGKPRRLKREDCPTIASIVTTLRDK
                     DMLPAIYVIFSRKGCDQAIRELKNLNLVNPEEARAIYYRLLIFFLEDNPNLQELALSFF
                     AVENPPLHQKLLAFFANNPQSDEQLLSLLTADPETKNQLFEFLASASQLVRADQVEPLT
                     RGCGVHHAGILPLWKELVEQLFEAGLIKVVFATATLSAGINMPARTTVISALSKRTDDG
                     HSMLTPSEFVQIAGRAGRRGMDAVGHVVTVQTPFEGAKEAAFLATAQPEPLQSCFAPSY
                     GMVLNLLQKHSLEQAKDLLERSFAEYLARLKLSPERQQITALTTELAKLDMELAGIERE
                     QVFSYEKLRERLREEERLYKIIASQSEAQKRQEIHLKLPNIPVGTILHLKGKHIKVPVP
                     VPAIFVNTLHGAGQVRTLVCLGSDNRWYLAAYADISEIDRGFLTPAELGELIPPSLAAV
                     SLGGWRKGEENTQAIADSIPQQVQGIPPVVELETQAQRIEIVNSQIAAHPLQKRKNPGR
                     LMKLYYDREIARDKLYKAQIKYQKQQSRKSYYWEEFLNLIEILREFQALEGYLPTPLGE
                     AAATIRGENELWLGLAMMSGDLDRLTPSQLAAAISAMITEPPRPDTWCNYPPVPEVIDI
                     LRQGEGNSPGLREVRRLLYQAQSRYDITIPVWLETQLMGIASRWAQGTSWPELCENTSL
                     DEGDLVRLLRRTVDVLWQIPQIPRVSQVLKDNARLAVTAMKRFPL"
     cand_cluster    3191..24123
                     /candidate_cluster_number="2"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    3191..24123
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[13190:14123](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      13191..14123
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="2"
     misc_feature    3885..3900
                     /note="TFBS match to CsoR, Copper-responsive repressor,
                     confidence: weak, score: 20.67"
                     /tool="antismash"
     gene            4119..5051
                     /locus_tag="LC603172_RS25770"
                     /old_locus_tag="MAN88_50030"
     CDS             4119..5051
                     /EC_number="2.7.7.65"
                     /GO_function="GO:0009975 - cyclase activity [Evidence IEA]"
                     /GO_process="GO:0009966 - regulation of signal transduction
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002787322.1"
                     /locus_tag="LC603172_RS25770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MAN88_50030"
                     /product="diguanylate cyclase"
                     /protein_id="WP_061433230.1"
                     /transl_table=11
                     /translation="MINFSAEDCLVLVVDDVSKNLQLAVEILDSAGYATIFASSFKQAI
                     EQVKTANPDLILLDLMMPEMGGIEVCRRLKTDNLYAHIPIIFVTDSKEKEDILNAFNSG
                     AVDYVNKPFHSWELLARVKIHLELKKTQEELKNINSQLEKLVRTDSLTGVNNRREILYL
                     GEKEFQRCRRYHRYFSVLFIDIDHFKHINDTFGHILGNKTLITVAGAIKTCLRQVDSFG
                     RFGGEEFVAILPETNLEDAATTAQRICQVINKLNIELAQQKVPVTASIGVATFSPQDNN
                     LEEVIERADHAMLAAKNQGRNRVSLGKTV"
     gene            5048..5830
                     /locus_tag="LC603172_RS25775"
                     /old_locus_tag="MAN88_50040"
     CDS             5048..5830
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1091: glutamine-binding lipoprotein glnH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002787323.1"
                     /locus_tag="LC603172_RS25775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MAN88_50040"
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="WP_061433191.1"
                     /transl_table=11
                     /translation="MKNLLFILGFLLLGVAPSFSADLDTIIRRGKLIVAVKNNLPPLAF
                     LDSQGNLQGLEIDIAKRLAEEILGSDSAIILKPVSNQERLQVVIDDRVDLAIARVAITP
                     ARQRLVDFSPFYYLDSSGFVTKNLLFQRLEDLANSRIAVLNGSTTIALVRSHLPKATLR
                     GVASYQEALNLLETGEIDAFAADNSLLTGWVQQFPNYRQLPIQLGAIALGVVLPKGLQY
                     QSLRERVNQAIERLESTGWLVERVNYWGLPLRIREMGR"
     gene            complement(5798..5944)
                     /locus_tag="LC603172_RS25780"
     CDS             complement(5798..5944)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002739689.1"
                     /locus_tag="LC603172_RS25780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_155726787.1"
                     /transl_table=11
                     /translation="MSFQFTVHCSQQKTPHTPHPTPHFPHPTPHTPHPTPHTLSPHFPN
                     SQG"
     gene            6033..6569
                     /locus_tag="LC603172_RS25785"
                     /old_locus_tag="MAN88_50050"
     CDS             6033..6569
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1272: TPR
                     repeat-containing protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002795535.1"
                     /locus_tag="LC603172_RS25785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MAN88_50050"
                     /product="tetratricopeptide repeat protein"
                     /protein_id="WP_002795535.1"
                     /transl_table=11
                     /translation="MEDTLPLIYVSGLLIFVIGLGIFVIVQIFKTRRVEGTFNKLQKKL
                     QKEKGTAKEYYELGSLYLDKKLYVQALSLLQKALKISEEESIEPENQALIYNALGFSYF
                     AQEQLELAIRNYKEAIKLYPEYSIALNNLGNVYEKKQMAKKALETYEETLKFDPNNTVA
                     KKRAESLRKRFAESK"
     gene            complement(6624..8423)
                     /locus_tag="LC603172_RS25790"
                     /old_locus_tag="MAN88_50060"
     CDS             complement(6624..8423)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016516128.1"
                     /locus_tag="LC603172_RS25790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MAN88_50060"
                     /product="SLC13 family permease"
                     /protein_id="WP_061433190.1"
                     /transl_table=11
                     /translation="MPTPIILTLTVLVVALVAFVAEWLPVDLTALCVAIVLILLGLVTP
                     EEGIAGFSNSATVTVMAMFVLSAGITRTGVIQVIRDRLLVWGGKNPHQQVFVLGALVGP
                     ISAFINNTAVVAIFLPIVEDWCKKQKISPSKLLIPLSYATVLAGMITVVGTSTNILASG
                     ISAKLGYGEFSLFQFTALGLVTFLAGLIYLTIFAPKLLPDRKSSTGEFLEDDYGSKVYL
                     SEVIITPRSNLIGQTLSQSGLQRKFNFDVLELIRNKVHLSQPLADKVLNAADILIVHSS
                     REELLKIKDERGLEIFADVKFQKVDIESTITTGEEKLAEVLILSNSRLIGTTLKDLKFR
                     QRYNATVLAIRRGSELLQGRLGKIPLKFGDLLLVQGPKQSFIGLQTTRELLVLEEKEIE
                     SLRQDKGIIALMITLLVIIIAAFDIQPILVTSLVGVVLMVITGCLKPGEVYGSIRWDII
                     FLLAGLIPLGTAMDNSGTTKWLADNLVAIGGHLSGFWILVFFYLITSVLTEILSNNAAV
                     VLMIPVAVEVAKTLGLNPLAFMYAVTFAASNSYLTPIGYQTNTMVYAPGGYKFLDFTRL
                     GAPLNLILTILTPVLIVVFYGLK"
     gene            complement(8428..11208)
                     /locus_tag="LC603172_RS25795"
                     /old_locus_tag="MAN88_50070"
     CDS             complement(8428..11208)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1037: heavy metal
                     translocating P-type ATPase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012264728.1"
                     /locus_tag="LC603172_RS25795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MAN88_50070"
                     /product="cation-translocating P-type ATPase"
                     /protein_id="WP_061433189.1"
                     /transl_table=11
                     /translation="MTFPTTSPQVSEIENNRAWHNLTGEQTLEILRTNGETGLNEAEIV
                     KRKDFFGLNELKETGGRSPLMILWEQFTNIMLVMLIAVAVVSAVLDLKKGEFPKDAIAI
                     FTIVILNGILGYLQESRAEKALAALKQLSSPKVRVIRNGSTFEVTAKELVPGDIMLLEA
                     GVQIAADGRLLEAQNLQIREAALTGEAESVNKQAQKVLPEDASLGDRINLVYQGTEVVQ
                     GRGKVAITKTGMDTEIGKIAAMLQGVESEPTPLQQRMSQLGNVLVSGSLALVAVVVLWG
                     VISSGWQFFESLLETSLSMAVAVVPEGLPAVVTVTLAIGTQRMVRRQALIRKLPAVETL
                     GSVTTICSDKTGTLTQNKMVVQKVNTSEQTITVTGEGYAPIGEFNGASESDPELQAILT
                     ACVLCNDALLQNKAQEWSILGDPTEGALLTLAGKGGLYREALAPQSPRLGEFPFSSERK
                     RMSVICENAQLGLGDSAYLMFTKGSPELILERCSLIQVGAESQPLTAEQRSRILAQNDE
                     MAGNGLRVLGFSYKPMTEVPEAEREDSEEQSLVWLGLVGMLDAPRKEVKEAVALCRQAG
                     IRPIMITGDHQLTAKAIAIELGIAAPGERVITGKELEKMSQNDLEGEVDGVSVYARVSP
                     EHKLRIVQALQKRGKFVAMTGDGVNDAPALKQADIGIAMGITGTDVSKEASDMILLDDN
                     FATIVAATEEGRVVYSNIRRFIKYILGSNIGEVLTIAAAPLLGLGGVPLSPLQILWMNL
                     VTDGLPALALAMEPAEPNVMKRPPFSPRESIFARGLGWYMIRIGIVFAILTIIMMYWAY
                     QYTQATPEIGDPGRWKTMVFTTLCLAQMGHALAVRSHTQLAVQMNPFSNPYIIAAVGLT
                     TILQLLLIYAPPLQSFFGTQWISGTELLICFGFSALMFVWIELEKLFIRWFMTKK"
     gene            11298..11579
                     /locus_tag="LC603172_RS25800"
     CDS             11298..11579
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="LC603172_RS25800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_260324472.1"
                     /transl_table=11
                     /translation="MTSYQLSVTSYQLSVTSKQLSVTSNQLSVTSNQLSVTSNQLSVTS
                     QQLSRKWGSGEMGKLSHHPITPKPHHPKTLSPYHPISSCPLPTDFSII"
     gene            11655..13085
                     /gene="pds"
                     /locus_tag="LC603172_RS25805"
                     /old_locus_tag="MAN88_50080"
     CDS             11655..13085
                     /EC_number="1.3.5.5"
                     /GO_function="GO:0016166 - phytoene dehydrogenase activity
                     [Evidence IEA]"
                     /GO_process="GO:0016117 - carotenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="pds"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016516130.1"
                     /locus_tag="LC603172_RS25805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MAN88_50080"
                     /product="15-cis-phytoene desaturase"
                     /protein_id="WP_061433188.1"
                     /transl_table=11
                     /translation="MRVAIAGAGLAGLSCAKYLVDAGHTPIVLERRDVLGGKIAAWKDA
                     DGDWYETGLHIFFGAYPNMLQLFQELGIEDRLQWKEHSMIFNQPEKPGTYSRFDFPDIP
                     APINGIVAILRNNDMLTWEEKIKFGLGLIPAIVKGQSYVEEMDKYSWSEWLEKQNIPPR
                     VEKEVFIAMSKALNFIDPNEISATILLTALNRFLQEKNGSKMAFLDGSPPERLCQPLVD
                     YITARGGEVRLNAPLKEIVLNEDGTVKAFLMRGLDGGEDYLFEADLYVSAMPVDPLKVL
                     LPKPWQEDKFFQKLEGLEGVPVINLHLWFDRKLTDIDHLLFSRSPLLSVYADMSNTCKE
                     YANPDRSMLELVLAPAQDWISKSDEEIIAATMKELEKLFPQHFTGDNPSQLLKYHLVKT
                     PRSVYKATPGRQAYRPSQKTPIENFYLAGDYTMQKYLGSMEGAVLSGKLAAAVISKDHP
                     AAPLNPNKTQSIPVSSAR"
     gene            13191..14123
                     /gene="crtB"
                     /locus_tag="LC603172_RS25810"
                     /old_locus_tag="MAN88_50090"
     CDS             13191..14123
                     /EC_number="2.5.1.32"
                     /GO_function="GO:0004311 - farnesyltranstransferase
                     activity [Evidence IEA]"
                     /GO_function="GO:0016767 - geranylgeranyl-diphosphate
                     geranylgeranyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0016117 - carotenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="crtB"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008206008.1"
                     /locus_tag="LC603172_RS25810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MAN88_50090"
                     /product="15-cis-phytoene synthase CrtB"
                     /protein_id="WP_002795540.1"
                     /sec_met_domain="phytoene_synt (E-value: 1.4e-101,
                     bitscore: 337.6, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 4.4e-86,
                     bitscore: 287.2, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLQLPKPTHPTKPLVSLAESYELCRRITEKYSKTFYLGTLLMPKA
                     KRQAIWAIYVWCRRTDELVDGPQARLTTPETLDLWEKQLETVFSGVAIEDADVALVDTL
                     EKFPMDIQPFRDMIAGQQMDLYRSRYQTFDELKLYCYRVAGTVGLMSSAVLGLEDDDRS
                     APWRRNQSVYIPQEEAIDLGIANQLTNILRDVGEDVHRGRIYLPLEDLERFNYSEDDLL
                     KGVNDHRWQALMRFQIERARYYYDSAERGIRALNPDSRWPVWAALLLYQGILDVIEANN
                     YDVFARRAFVPLPKKMLYLPVAWLRSQAL"
     gene            complement(14457..14933)
                     /locus_tag="LC603172_RS25815"
                     /old_locus_tag="MAN88_50100"
     CDS             complement(14457..14933)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002740677.1"
                     /locus_tag="LC603172_RS25815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MAN88_50100"
                     /product="hypothetical protein"
                     /protein_id="WP_061433187.1"
                     /transl_table=11
                     /translation="MNTRELPALASIPSKKLPGWGAEVNSPDGGGTCQSFPLPLVLGGK
                     AMKSATLLSPDRPLPEFLRSAIQERFPGKAIDDLSIRYYESVEDVGYEYFNDRVLPSCS
                     DEPVVRYLGPFISYVRLGEALVLDRQEGLVVYETERDVPCTETGPFWLVTPKSR"
     gene            15191..15433
                     /locus_tag="LC603172_RS25820"
                     /old_locus_tag="MAN88_50110"
     CDS             15191..15433
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002737723.1"
                     /locus_tag="LC603172_RS25820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MAN88_50110"
                     /product="hypothetical protein"
                     /protein_id="WP_002795543.1"
                     /transl_table=11
                     /translation="MTIYVTREGDKLVADSPLELVEKLQQCQGRMAETRQDFMTRMAAQ
                     MVASQGVTVPITDPENFIAELIHNDFLSVVDSIDG"
     gene            complement(15494..16186)
                     /locus_tag="LC603172_RS25825"
                     /old_locus_tag="MAN88_50120"
     CDS             complement(15494..16186)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1208: pirin
                     domain-containing protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002799908.1"
                     /locus_tag="LC603172_RS25825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MAN88_50120"
                     /product="pirin family protein"
                     /protein_id="WP_061433186.1"
                     /transl_table=11
                     /translation="MITIRKAEERGHANYGWLDTYHTFSFAQYYDPQQINFRSLRVINE
                     DKVIGGKGFHTHGHHDMEILTYVLEGELEHQDSLGTGSVIRHGEIQRMSAGTGIKHSEF
                     NHSATNPLHLLQIWIIPDSKNLEPSYEQKAIEFSPHTLQLIASPTGAGKAVKVHQDVNL
                     YAGILPLGQSLTHPLAPSRYGWLQVARGQITVNGVHLRAGDGAAISEETSLAIQSLEDS
                     EILLFDLG"
     gene            16835..17398
                     /locus_tag="LC603172_RS25830"
                     /old_locus_tag="MAN88_50130"
     CDS             16835..17398
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="LC603172_RS25830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="MAN88_50130"
                     /product="hypothetical protein"
                     /protein_id="WP_061433185.1"
                     /transl_table=11
                     /translation="MINTRLKPVTTGLIGAVGLGVALLGMPEMAEAVDIKAGIDYLFTP
                     KGSDTWVDFDRNGPNGRTYFKGVPILPGGTDTAVKRLDDCHFDINGKCTVGLQFVSLNL
                     ESVKPVPDFGNQIVFLMLDDSHTQPVSSMTIMDIGNNMATWTNTLDFYWKLVDSDSNVL
                     ATGFESFIGSGKGTYGSSLLGMVR"
     gene            17633..17719
                     /locus_tag="LC603172_RS25835"
     CDS             17633..17719
                     /GO_component="GO:0031240 - external side of cell outer
                     membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:TIGR02595.1"
                     /locus_tag="LC603172_RS25835"
                     /note="PEP-CTERM proteins occur, often in large numbers, in
                     the proteomes of bacteria that also encode an exosortase, a
                     predicted intramembrane cysteine proteinase. The presence
                     of a PEP-CTERM domain at a protein's C-terminus predicts
                     cleavage within the sorting domain, followed by covalent
                     anchoring to some some component of the (usually
                     Gram-negative) cell surface. Many PEP-CTERM proteins
                     exhibit an unusual sequence composition that includes large
                     numbers of potential glycosylation sites. Expression of one
                     such protein has been shown restore the ability of a
                     bacterium to form floc, a type of biofilm.; PEP-CTERM
                     proteins occur, often in large numbers, in the proteomes of
                     bacteria that also encode an exosortase, a predicted
                     intramembrane cysteine proteinase. The presence of a
                     PEP-CTERM domain at a protein's C-terminus predicts
                     cleavage within the sorting domain, followed by covalent
                     anchoring to some some component of the (usually
                     Gram-negative) cell surface. Many PEP-CTERM proteins
                     exhibit an unusual sequence composition that includes large
                     numbers of potential glycosylation sites. Expression of one
                     such protein has been shown restore the ability of a
                     bacterium to form floc, a type of biofilm; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /product="PEP-CTERM sorting domain-containing protein"
                     /protein_id="WP_239698213.1"
                     /transl_table=11
                     /translation="MPEPSTVLGLIAVGLSSIVGFKGKKEPK"
     gene            complement(18382..18924)
                     /locus_tag="LC603172_RS25840"
                     /old_locus_tag="MAN88_50140"
     CDS             complement(18382..18924)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002740671.1"
                     /locus_tag="LC603172_RS25840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MAN88_50140"
                     /product="Uma2 family endonuclease"
                     /protein_id="WP_072319874.1"
                     /transl_table=11
                     /translation="MVIVEDELKEIIFPKSDLLSDEPPMETELHLRQLMLLIQSLELLW
                     KDRQDFYAFGNLTIYYSPNQRKSEYFRGPDFFVVLGVARKPRKSWVVWEEEGKYPHVII
                     EILSDSTAETDRGLKKEIYQETFRTPNYFWFDLTSLEFKGFQLMAGKYEEIAANEQGWL
                     WSQQLELFLGIHRKFWV"
     gene            18923..19882
                     /locus_tag="LC603172_RS25845"
                     /old_locus_tag="MAN88_50150"
     CDS             18923..19882
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002762572.1"
                     /locus_tag="LC603172_RS25845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MAN88_50150"
                     /product="enediyne biosynthesis protein UnbU"
                     /protein_id="WP_061433184.1"
                     /transl_table=11
                     /translation="MTTTQLFNLPYFSSSVERSTVSYQPNRLAGLRRFAIAITFLNILG
                     HTVLGFEQSWAQPLVALATGYSVELLLESVDARVNGFKPRYLGSIGQFVDFLLSAHITS
                     LAIAMLLYANERLFPIMFAVAVAIGSKAIFRLQVADKTRHFLNPSNFGISVTLLLFPWI
                     GIAPPYQFTENLSGWADWILPVLIVCTGTFLNARFTRKLPLIAGWLGAFILQAILRSAI
                     FHTALIPALLPMTGVAFVLFTFYMVTDPGTTPINPREQIIFGASVAVAYGILMSFHVVF
                     GMFFGLTLVCCFRGLILAVEPLKAKLPLVQASGILSTP"
     gene            20001..25940
                     /locus_tag="LC603172_RS25850"
                     /old_locus_tag="MAN88_50160"
     CDS             20001..25940
                     /EC_number="6.4.-.-"
                     /NRPS_PKS="Domain: PKS_KS(Enediyne-KS) (6-460). E-value:
                     1.8e-99. Score: 325.4. Matches aSDomain:
                     nrpspksdomains_LC603172_RS25850_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (607-844). E-value: 1.3e-49.
                     Score: 161.1. Matches aSDomain:
                     nrpspksdomains_LC603172_RS25850_PKS_AT.1"
                     /NRPS_PKS="Domain: PP-binding (936-1004). E-value: 7.2e-07.
                     Score: 21.4. Matches aSDomain:
                     nrpspksdomains_LC603172_RS25850_PP-binding.1"
                     /NRPS_PKS="Domain: PKS_KR (1210-1390). E-value: 1.9e-34.
                     Score: 111.1. Matches aSDomain:
                     nrpspksdomains_LC603172_RS25850_PKS_KR.1"
                     /NRPS_PKS="Domain: PKS_DH (1469-1570). E-value: 5.8e-07.
                     Score: 22.0. Matches aSDomain:
                     nrpspksdomains_LC603172_RS25850_PKS_DH.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     ene_KS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022: Beta-ketoacyl synthase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008205986.1"
                     /locus_tag="LC603172_RS25850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MAN88_50160"
                     /product="type I polyketide synthase"
                     /protein_id="WP_061433183.1"
                     /sec_met_domain="ketoacyl-synt (E-value: 2.8e-52, bitscore:
                     176.1, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="ene_KS (E-value: 2.8e-228, bitscore:
                     756.3, seeds: 19, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 1.2e-47, bitscore: 161.1,
                     seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short (E-value: 2.4e-29, bitscore:
                     101.0, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKASPQIAIVGMACLYPDADSPQELWENVLSQRRAFRRFPSERLS
                     LSDYYSPDKSTPDVIYSTQAAVIEGYEFDRIAYKVVGSTFRSADLAHWLALDIASQALN
                     DAGFPDGKGLNKETTGVLLGNTLTGELSRANTLRLRWPYVRHRVEEQLLKQGLSDKERQ
                     IFLNELENRFKEPFEPIGEESLAGNLSNTIAGRICNYFDLKGGGYIVDGACSSSLLAVA
                     NGCSALVAEDLDIALVGGVDISMDPFELVGFAKTGALASGEMKVYDQGSNGFIPGEGCG
                     FLVLMRHGDALAQNKRIYAVIQGWGISSDGKGGITRPEVEGQLLALNRAYKRAEFTGDT
                     IAYFEGHGTGTAVGDGTELEVLSRIHPDTVNKAVIGSIKANIGHTKAAAGIAGLIKATM
                     AVHRQILPPVTGCDRPQAQLTEDKARLQVLKEGQIWPNSLPLRAAVSAMGFGGINSHII
                     IEGLSQIRRHTLTPQEQKLIHSPQDAELFLLSANRQEDLQAQVNRLLNIVPRISQSEMT
                     DLAVELAKKVNPHLPYRLAIIASSPDSLTNQLVGAQGLHSLIPPGQNLDNIFTNNEKQI
                     NKIGFLFPGQSAPVYLHGGLWERRFPVIKQLYNKAQLAKGKDNTVTNIAQPAIITACLG
                     GLQLLENLNIKADLAIGHSLGELCALFWANAYDKTQLINLAKIRGQAMAQLGHPTGRMA
                     SINADAETVKSLLNGRIVEIAGLNSPYQTIISGEALGIKDVVEKAQNKGIKTVYLPVSH
                     AFHSPLVARAVQPLEDYLQTYPLNSLEKTVISTVTGEKLPLNTDWRSLLLEQITSPVRF
                     IDAVKSAEKEVDLFIEVGSGSILSRLVADITDIPVISLDSSSESLQGLLKTVAVMFVNG
                     VKVNYQGLFEDRFSRPFNLDYQPHFIANPCEIKVKGKSQQAKVENIALLLPNHSQNLKP
                     ETSKIEVIRQLVAQKTELPLETIENHHRLLADLHLNSISVSQLVIEAARQLDLSPPHSP
                     TDYANATIQDLAAALEELGKNNPQIPQESIPMGVDNWVRAFTVELIEKPLIKSDKKQIN
                     REKAGNWHIIAHADHPLLPNLSVLQPTLKHEQEKGIIICLKSHPDESEIDLLLKGAKLS
                     IKEKKPLILIQQGGGYASFARTFYLENRQIPTCVIDIPFHHPNAVNIILSEITATDSYT
                     EVYYDENGKRFVRQLNLLGLEKDTDNPKQKKALKSSNKSKIKELLLVTGGGRGIASECA
                     LSLAKENKATLAILGRSQPEDNRELAENLARMKSANIQVHYYSCDVSDAESVQQTIAEI
                     KTNLGEITGILHGAGVNTPKLIQHLEPEDFLATLAPKVKGLQHILTEINPDSLNYLITF
                     GSIIAETGLKGEADYGLANEWLGDIVAEFSQKYPNCRCLNLEWSVWSGIGMGERLGTVE
                     KLRNEGITPISPDIGIKYLHLLLNQSLPTASVIIAGRFGEPPTLSLKPQELSFLRFLET
                     KKVHYTGIELITEAELSLDNDPYLQDHVYQGEYIFPGVLGLEAIAQVATALLPTLARKE
                     DQTLNKGENQDPPSVPLNKGETGGLRFESVKFNRPIVVSADKPLKIQIATLITDSGKVK
                     AVIRCANTGFSIDHFEAIISHSSVGAPDCRPLIPPVPLKEGKNNPQINPDTDLYGHLLF
                     HKARFQRIKGYSHLKATECIAEINIEPKTAWFSRYLPQSLILGDAGARDAVIHALQACV
                     PHATILPTGIERLTVYSVNLGENQFVSAKERLHQGDTFVYDLEVLDDDGNLLEVWQGLE
                     LKVIKHRNPQDPWIPALLPCYLERKIKEVMPNVDLTLILDRDATVERRVRSDRSLGMLT
                     SSPSVIQRRGDGKPELSDNETVSVSHAEDLTLVLKGASGCDLEPIIPRDVQMWRDLLGE
                     NSFNLAEVISQENHEDFNMAATRIWSAKESIKKAGLSLDIPLTLSSFSQQLTPLSPILW
                     LSSGKDLIITLPVSFREIKTAFILAIFVQTVPEKSDLLQTEPLKFF"
     aSDomain        20019..21380
                     /ASF="found active site cysteine: True, scaffold matched
                     GSSS: True"
                     /ASF="found active site histidines: True"
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_LC603172_RS25850_PKS_KS.1"
                     /domain_subtypes="Enediyne-KS"
                     /evalue="1.80E-99"
                     /label="LC603172_RS25850_PKS_KS.1"
                     /locus_tag="LC603172_RS25850"
                     /protein_end="460"
                     /protein_start="6"
                     /score="325.4"
                     /tool="antismash"
                     /translation="IAIVGMACLYPDADSPQELWENVLSQRRAFRRFPSERLSLSDYYS
                     PDKSTPDVIYSTQAAVIEGYEFDRIAYKVVGSTFRSADLAHWLALDIASQALNDAGFPD
                     GKGLNKETTGVLLGNTLTGELSRANTLRLRWPYVRHRVEEQLLKQGLSDKERQIFLNEL
                     ENRFKEPFEPIGEESLAGNLSNTIAGRICNYFDLKGGGYIVDGACSSSLLAVANGCSAL
                     VAEDLDIALVGGVDISMDPFELVGFAKTGALASGEMKVYDQGSNGFIPGEGCGFLVLMR
                     HGDALAQNKRIYAVIQGWGISSDGKGGITRPEVEGQLLALNRAYKRAEFTGDTIAYFEG
                     HGTGTAVGDGTELEVLSRIHPDTVNKAVIGSIKANIGHTKAAAGIAGLIKATMAVHRQI
                     LPPVTGCDRPQAQLTEDKARLQVLKEGQIWPNSLPLRAAVSAMGFGGINSHIIIE"
     aSModule        20019..23012
                     /complete
                     /domains="nrpspksdomains_LC603172_RS25850_PKS_KS.1"
                     /domains="nrpspksdomains_LC603172_RS25850_PKS_AT.1"
                     /domains="nrpspksdomains_LC603172_RS25850_PP-binding.1"
                     /locus_tags="LC603172_RS25850"
                     /monomer_pairings="mal -> mal"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       21126..21170
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_LC603172_RS25850_0001"
                     /evalue="2.30E-03"
                     /label="PKSI-KS_m6"
                     /locus_tag="LC603172_RS25850"
                     /protein_end="390"
                     /protein_start="375"
                     /score="10.6"
                     /tool="antismash"
                     /translation="GSIKANIGHTKAAAG"
     aSDomain        21822..22532
                     /ASF="(Methyl)Malonyl-CoA specificity inconclusive"
                     /ASF="found active site serine: True, scaffold matched
                     GHGE: True"
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_LC603172_RS25850_PKS_AT.1"
                     /evalue="1.30E-49"
                     /label="LC603172_RS25850_PKS_AT.1"
                     /locus_tag="LC603172_RS25850"
                     /protein_end="844"
                     /protein_start="607"
                     /score="161.1"
                     /specificity="substrate consensus: mal"
                     /specificity="PKS signature: Malonyl-CoA"
                     /specificity="Minowa: mal"
                     /tool="antismash"
                     /translation="YNKAQLAKGKDNTVTNIAQPAIITACLGGLQLLENLNIKADLAIG
                     HSLGELCALFWANAYDKTQLINLAKIRGQAMAQLGHPTGRMASINADAETVKSLLNGRI
                     VEIAGLNSPYQTIISGEALGIKDVVEKAQNKGIKTVYLPVSHAFHSPLVARAVQPLEDY
                     LQTYPLNSLEKTVISTVTGEKLPLNTDWRSLLLEQITSPVRFIDAVKSAEKEVDLFIEV
                     GSGSILSRLVADITD"
     CDS_motif       21942..22049
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_LC603172_RS25850_0002"
                     /evalue="1.10E-04"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="LC603172_RS25850"
                     /protein_end="683"
                     /protein_start="647"
                     /score="14.0"
                     /tool="antismash"
                     /translation="DLAIGHSLGELCALFWANAYDKTQLINLAKIRGQAM"
     aSDomain        22809..23012
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_LC603172_RS25850_PP-binding.1"
                     /evalue="7.20E-07"
                     /label="LC603172_RS25850_PP-binding.1"
                     /locus_tag="LC603172_RS25850"
                     /protein_end="1004"
                     /protein_start="936"
                     /score="21.4"
                     /tool="antismash"
                     /translation="VIRQLVAQKTELPLETIENHHRLLADLHLNSISVSQLVIEAARQL
                     DLSPPHSPTDYANATIQDLAAAL"
     aSDomain        23631..24170
                     /ASF="KR domain putatively catalyzing L-configuration
                     product formation"
                     /ASF="catalytic triad S,Y,N inconclusive"
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_LC603172_RS25850_PKS_KR.1"
                     /evalue="1.90E-34"
                     /label="LC603172_RS25850_PKS_KR.1"
                     /locus_tag="LC603172_RS25850"
                     /protein_end="1390"
                     /protein_start="1210"
                     /score="111.1"
                     /specificity="KR activity: active"
                     /specificity="KR stereochemistry: (unknown)"
                     /tool="antismash"
                     /translation="LLVTGGGRGIASECALSLAKENKATLAILGRSQPEDNRELAENLA
                     RMKSANIQVHYYSCDVSDAESVQQTIAEIKTNLGEITGILHGAGVNTPKLIQHLEPEDF
                     LATLAPKVKGLQHILTEINPDSLNYLITFGSIIAETGLKGEADYGLANEWLGDIVAEFS
                     QKYPNCRCLNLEWSVWS"
     aSModule        23631..24710
                     /domains="nrpspksdomains_LC603172_RS25850_PKS_KR.1"
                     /domains="nrpspksdomains_LC603172_RS25850_PKS_DH.1"
                     /incomplete
                     /locus_tags="LC603172_RS25850"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       23634..23726
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_LC603172_RS25850_0003"
                     /evalue="2.10E-04"
                     /label="PKSI-KR_m1"
                     /locus_tag="LC603172_RS25850"
                     /protein_end="1242"
                     /protein_start="1211"
                     /score="14.0"
                     /tool="antismash"
                     /translation="LVTGGGRGIASECALSLAKENKATLAILGRS"
     aSDomain        24408..24710
                     /aSDomain="PKS_DH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_LC603172_RS25850_PKS_DH.1"
                     /evalue="5.80E-07"
                     /label="LC603172_RS25850_PKS_DH.1"
                     /locus_tag="LC603172_RS25850"
                     /protein_end="1570"
                     /protein_start="1469"
                     /score="22.0"
                     /tool="antismash"
                     /translation="ELITEAELSLDNDPYLQDHVYQGEYIFPGVLGLEAIAQVATALLP
                     TLARKEDQTLNKGENQDPPSVPLNKGETGGLRFESVKFNRPIVVSADKPLKIQIAT"
     gene            25990..26556
                     /locus_tag="LC603172_RS25855"
                     /old_locus_tag="MAN88_50170"
     CDS             25990..26556
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002762574.1"
                     /locus_tag="LC603172_RS25855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MAN88_50170"
                     /product="hypothetical protein"
                     /protein_id="WP_061433182.1"
                     /transl_table=11
                     /translation="MTTVRQIPNQRNPIQLISNIIRSFVYAMNGRWHKLGMQIFMIVTI
                     AHISEHIIQAYQLWVLGWPRPECLGLLGLWKPWLMRSEWLHYGHALFMLLGLAIFRPSF
                     HGKARLWWDLALGLQFYHHFEHALLLGQAIIGQNLWYSPVRTSIGQIWFPRLELHLFYN
                     LMVLIPMMIAMYYHRFPPMNEGRLV"
     gene            complement(26691..26936)
                     /locus_tag="LC603172_RS25860"
                     /old_locus_tag="MAN88_50180"
     CDS             complement(26691..26936)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002762575.1"
                     /locus_tag="LC603172_RS25860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MAN88_50180"
                     /product="hypothetical protein"
                     /protein_id="WP_221275428.1"
                     /transl_table=11
                     /translation="MPFLSTIEEMALEEGAKSGAKLTNQKHIILALQSRFGEIPNSLIE
                     TINQIEDVSVLESLFVPSITINSLEEFQQIVNDSLS"
     gene            complement(26960..27901)
                     /locus_tag="LC603172_RS25865"
                     /old_locus_tag="MAN88_50190"
     CDS             complement(26960..27901)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012264716.1"
                     /locus_tag="LC603172_RS25865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MAN88_50190"
                     /product="hypothetical protein"
                     /protein_id="WP_221275429.1"
                     /transl_table=11
                     /translation="MAEVTANYDKTWKEAISTYLAEFLSFFYPNIYQEIDWNQTPISLD
                     KELEKITAAAETEQRYADKLLKVWLLDNQEIWLLIHIEVQSQYDLKFPQRMFIYNYRAF
                     DLYHKPVISLAILGDESRSWRPDFYQYGLGGSQVRVDFLMVKLLDYQWEDLEQSENIWA
                     IIVMAHLKTKATTNNLREREQWKWNLVRGLYQRGLTKFEIINLGKFIDKMMTLPPQLQL
                     NFKTKLSQYEEENKMPFLSTIEEMALEEGAKLTNQKHIILALQSRFGEIPNSLIETINQ
                     IEDVSVLESLFVPSITINSLEDFQQLVNDSLS"
     misc_feature    27942..27955
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 21.45"
                     /tool="antismash"
     gene            27956..28168
                     /locus_tag="LC603172_RS25870"
                     /old_locus_tag="MAN88_50200"
     CDS             27956..28168
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002762577.1"
                     /locus_tag="LC603172_RS25870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MAN88_50200"
                     /product="hypothetical protein"
                     /protein_id="WP_155726785.1"
                     /transl_table=11
                     /translation="MDNSNPTPIPCENSDISSLETANHKPFWKAIVEIGEKVPIEEWNK
                     LPKDFARNAEHYMYGAPRDEDYEEE"
     gene            28165..28578
                     /locus_tag="LC603172_RS25875"
                     /old_locus_tag="MAN88_50210"
     CDS             28165..28578
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012264714.1"
                     /locus_tag="LC603172_RS25875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MAN88_50210"
                     /product="type II toxin-antitoxin system VapC family toxin"
                     /protein_id="WP_002795552.1"
                     /transl_table=11
                     /translation="MRKIFLDTFYLQALADYQDNAHQIALNMTDNLGNFLSVTSEMVLT
                     ELLNALSGRGGYLRDAALDIVDKLHQDLSVEIIPQTSQLFAEALLLYRQRQDKSYSLTD
                     CASMLIMRQQNISDVLTFDRHFQQEGFNALLRN"
     gene            complement(28591..28974)
                     /locus_tag="LC603172_RS25880"
                     /old_locus_tag="MAN88_50220"
     CDS             complement(28591..28974)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012264713.1"
                     /locus_tag="LC603172_RS25880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MAN88_50220"
                     /product="hypothetical protein"
                     /protein_id="WP_002762579.1"
                     /transl_table=11
                     /translation="MNQPLTRFSQEWWSAYQTTWNEQENLGKKFTKLGKVILWFSDHQG
                     VSVCSEWDDQGQIVSLELIEEMDESLPIFSATRENWERFVNQEIGAVKAVMTGLIDYRG
                     SMTIIVKYGRHFDCLAEVAQKVN"
     gene            29302..29730
                     /locus_tag="LC603172_RS25885"
                     /old_locus_tag="MAN88_50240"
     CDS             29302..29730
                     /EC_number="3.1.2.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) 4HBT_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002795553.1"
                     /locus_tag="LC603172_RS25885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MAN88_50240"
                     /product="thioesterase family protein"
                     /protein_id="WP_002795553.1"
                     /sec_met_domain="4HBT_2 (E-value: 8.9e-15, bitscore: 53.5,
                     seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKAYEYHHIVSFQETNLVGNVYYANYVQWQGRCREMFLKDNAPDI
                     ITELCQGLALVTVRVSCEYLSELFAFDHVIIRMRLGEIKQNRITMLFEYWRVTDEGEEL
                     VAKGEQQTACMRREDGETRPTPIPAQLKLALENYHIPI"
     gene            complement(29925..31088)
                     /gene="devC"
                     /locus_tag="LC603172_RS25890"
                     /old_locus_tag="MAN88_50250"
     CDS             complement(29925..31088)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_component="GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /gene="devC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008205967.1"
                     /locus_tag="LC603172_RS25890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MAN88_50250"
                     /product="ABC transporter permease DevC"
                     /protein_id="WP_002762582.1"
                     /transl_table=11
                     /translation="MNIPTAWLQLAHKRTRLIVALSGIIFSTVIIFMQLGIRDALFESA
                     VHLHNSLEGDAFLISPRSTSLIAMESFSERRLLQVLSFNEVELVSPIYVGYAQWKNPDT
                     KNYWRNIFVIGIDLRYQAFKAVGIKENWQKLKIKYTTLFDQNSRREFGNIAEDFQKGKT
                     IITEVGNSGNNRKIEVVGLFELGTSFGSDGNLLMSYPNFLRIFQNRSSRFIDIGLIKFQ
                     PDIDRQSLLKKLKKYLPKDVKILSKQEFINFEKNYWATSTAIGFIFNLGVFLGLVVGIV
                     VVYQILYTNVAEHLAEYATLKAMGYHNRYLLWLVFQQALIIAVLGYIPGFLLGMIQYYF
                     TQKYTLLPIEMTPTRAIFVFGLTLLMSLIAGATAINKLQYADPADIF"
     gene            complement(31105..32472)
                     /locus_tag="LC603172_RS25895"
                     /old_locus_tag="MAN88_50260"
     CDS             complement(31105..32472)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1029: RND family
                     efflux transporter MFP subunit"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002795554.1"
                     /locus_tag="LC603172_RS25895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MAN88_50260"
                     /product="ABC exporter membrane fusion protein"
                     /protein_id="WP_061433181.1"
                     /transl_table=11
                     /translation="MTSCYLKQSLFDESLSLLTTMANFRLQNSYSLKYWFWGLLGAFMG
                     FSLGTTVIIFYFRPESSLKASQLSISPTVSPDTPEAVAALGYLEPQGGITQISATAFLE
                     GSRVDKILVKQGEKVEKGEIMAILDNNARLRAALKQAQANLGLAASKLEKVREGAKKGE
                     IMAQDSRMRQSKAELEGQIMRQTAAISSLESELEGEKLGQKATVERIKAELNNSLTDCQ
                     RYQSLYRNGAVSQGEKERFCLEATTTQKRLQEAEANLQRITTTLEQKIQEARANLQRTL
                     NTLEQQIQENQAMLSAVTEIRPVDLQIAQDEVMTAKANVERAQAELELSYVRAPHAGRI
                     LKIHTFPGELVKNEGILDLGNIQKMYVTAEVYETDISRVKLGQSVTIKTDKMLGDLEGT
                     VEEIGWKVGRQDVLGTDPVVDTDARVVEVKISLDHRSSAKVNRLTNLKVNVIIHPN"
     gene            32523..33575
                     /locus_tag="LC603172_RS25900"
                     /old_locus_tag="MAN88_50270"
     CDS             32523..33575
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002795556.1"
                     /locus_tag="LC603172_RS25900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MAN88_50270"
                     /product="DUF1702 family protein"
                     /protein_id="WP_061433228.1"
                     /transl_table=11
                     /translation="MASNFSGAPFEHPAVNFDHKFSPRQVNRFPQRLLLLSPQAATFNQ
                     RGFICDPQSRSPAAQPQKQIYLETIGQTFIYGYNAAIMAHSLTDLFPLLEGVTLNLRGF
                     AYEGAAMALSLLDCLTLGKRDRFEHFLANEGKKHIYMAYVGKGWQLARIPFSLRFYLQK
                     LEHSAQHFPDSLLGWLALDGYGFHQGYFAWPKYIRERKSPQELSGYARLVFAQGLGRSL
                     WFVKGANIPEIADQIQKFDPLLQPHLWSGIGLACTYAGGVSPEEIQHLKQLAEPYRAEL
                     AQGAAFAAKARLLAENCQENTEIACQILCGMAITETAKITDDTLIGLDYHDQIPAYEQW
                     RQAIQSHFRT"
     gene            33627..35525
                     /locus_tag="LC603172_RS25905"
                     /old_locus_tag="MAN88_50280"
     CDS             33627..35525
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002787355.1"
                     /locus_tag="LC603172_RS25905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MAN88_50280"
                     /product="CRTAC1 family protein"
                     /protein_id="WP_061433180.1"
                     /transl_table=11
                     /translation="MNRLEKFIRRHSKSILALGLILVLFFVSRLPALSMAERDAIASRF
                     AFTRFPLPELENQPYQVERPTNPSLSRHSAWISAVGAAVALGDLDGDGLDNDLCHVETQ
                     SNQVIISPVPGTGNRYQPFTLNVTDFDYNDQTMAPMGCIPSDLNEDGLRDLLVYYWGRT
                     PIAFIKQDQGYLQQQISQKREKWYTNAATFSDLDGDGHPDLIIGNYFPDNAEILDVNSQ
                     KIEKMQDSMTRAYNGGKNRVFLWSDASTTGVTYQEVQDAFEEKIAHGWTLAVGTADLDG
                     DLLPEIYLANDFGPDRLLHNRSTRGHLQFALLEGQKGLTTPNSKVLGHDGFKGMGVDFG
                     DINHDGLLDIYVSNIASEYALEESHFLFTSTGETEKMSRGIAPYVDKSEPLGVSRSGWS
                     WETKFGDFDNDGELEALQATGFRKGDINRWPELHELAMSNDQVLKIPNSWFHFQDGDDL
                     SGHQHNPFFVRGKDGRYYDLASQLSLDDPSVTRGIATADVDGDGDLDFVVANQWETSYF
                     YRNDSPNIGQSLELELLNPALSPNPSSEKGKMGIPAIGAAVKVSLPDGSQLVAQVDGGN
                     GHSGVRSPVLHFGLGKIDPNTALPVDIQWRNHKGEIKQTQLLLTSGKQTILLEQSV"
     misc_feature    35575..35594
                     /note="TFBS match to DosR, Hypoxia stress response
                     regulator, confidence: weak, score: 22.29"
                     /tool="antismash"
     gene            36030..36230
                     /locus_tag="LC603172_RS25910"
     CDS             36030..36230
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002740542.1"
                     /locus_tag="LC603172_RS25910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_155726783.1"
                     /transl_table=11
                     /translation="MATSKLVKPHTPHPTPHTLPPPKNFLPQTLIGHNEGIKQSLNLGK
                     TDIILMKGYGYQHPENLGDRS"
     gene            36190..36969
                     /locus_tag="LC603172_RS25915"
                     /old_locus_tag="MAN88_50290"
     CDS             36190..36969
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002782620.1"
                     /locus_tag="LC603172_RS25915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MAN88_50290"
                     /product="ABC transporter permease"
                     /protein_id="WP_061433179.1"
                     /transl_table=11
                     /translation="MGISILRIWAIAANSFREVIRDRILYFIGFFALLMAFAWRLLPEI
                     AVGTHQKIFLDLGLAAIGLLGVIVAVFVGTGLINKEIDKRTILVLIPKPLSRAEFILGK
                     HLGLSGVLAVMLGVMLVIYLLMLSGMKVSFQALPLIVSVFYLGLELILIAAVAIAFGVF
                     TSSILATLMTFGVYLMGHISKDLIQLGIISKNPNILAITKNIYLILPDLERLNFRNEAV
                     YGLLPSADVLIGNALYSLVYTGLLLGISILIFSRRQF"
     gene            37190..37654
                     /locus_tag="LC603172_RS25920"
                     /old_locus_tag="MAN88_50300"
     CDS             37190..37654
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002795559.1"
                     /locus_tag="LC603172_RS25920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MAN88_50300"
                     /product="hypothetical protein"
                     /protein_id="WP_061433178.1"
                     /transl_table=11
                     /translation="MKLKAQLHILSRDAVNYGLAPVVMEEAVNPVLAAMARQLKHLQYY
                     VVQNGQGDWLLTTLAHRRQPQQEKRVIYAFATEKMAISAQNTPNSPLSTLLIPVTHLLF
                     QLFALEKVDSIIFLENAHTAQTGKEITRTQLKANIEKQLQKLATIPANLA"
     gene            38072..38893
                     /gene="cysH"
                     /locus_tag="LC603172_RS25925"
                     /old_locus_tag="MAN88_50310"
     CDS             38072..38893
                     /EC_number="1.8.4.8"
                     /GO_function="GO:0004604 - phosphoadenylyl-sulfate
                     reductase (thioredoxin) activity [Evidence IEA]"
                     /GO_process="GO:0019379 - sulfate assimilation,
                     phosphoadenylyl sulfate reduction by
                     phosphoadenylyl-sulfate reductase (thioredoxin) [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="cysH"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002733238.1"
                     /locus_tag="LC603172_RS25925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MAN88_50310"
                     /product="phosphoadenosine phosphosulfate reductase"
                     /protein_id="WP_061433177.1"
                     /transl_table=11
                     /translation="MPDLHLLNSHTQALETAFIPTADRSFSSPLSLDLERINQRFDSAN
                     AAEIVAWSAATFGEGLVMSTSFGIQAAVMLHLVTAIIPDIPVIWIDTGYLPPETYQFAE
                     DLSQRLHLNLKVYQSPLSPARMEAIHGKLWSNNDLDSLNLYDKIRKVEPMQRALKELKA
                     TAWLAGLRRDQTDHRKTLQWVNQQGERYKILPILDWNAKTIYEYLTKYDLPYHPYFDLG
                     YVSVGDWHSSRPLTANDSNERDTRFKGLKQECGLHLPLTPGEAQSLDASSL"
     gene            39134..40000
                     /locus_tag="LC603172_RS25930"
                     /old_locus_tag="MAN88_50320"
     CDS             39134..40000
                     /NRPS_PKS="Domain: Abhydrolase_1 (37-250). E-value:
                     1.3e-16. Score: 52.9. Matches aSDomain:
                     nrpspksdomains_LC603172_RS25930_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1262: haloalkane dehalogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008202806.1"
                     /locus_tag="LC603172_RS25930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MAN88_50320"
                     /product="alpha/beta fold hydrolase"
                     /protein_id="WP_081106843.1"
                     /sec_met_domain="PF00561 (E-value: 3e-10, bitscore: 38.5,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 1e-07, bitscore:
                     31.2, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIINPPLTMAILENFLEVGSLKWFYRQVNPDQQPDTTPVILLHGL
                     PAHSYIWRELLTSLEEYNINAIAPDWIGSGLSAKPDAREFAYTPSAFCQALADFIQALQ
                     LPKISLIVQGFLASVGLQYALENPDKIERLIVLNTPLSRDVKLPWIMKQWGLPFLGDMA
                     TQDPLLVDRTLETGSGFVISDANLAIFRQPYLKTSAVGRALLATIRNLNLSKTMAEIET
                     GLEHFEKPILFVWGMADPWLSSVTVEKLATKSGVELIPLTEAKHYPQEHWSKEINPRII
                     NFLGRKT"
     aSDomain        39245..39883
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_LC603172_RS25930_Abhydrolase_1.1
                     "
                     /evalue="1.30E-16"
                     /label="LC603172_RS25930_Abhydrolase_1.1"
                     /locus_tag="LC603172_RS25930"
                     /protein_end="250"
                     /protein_start="37"
                     /score="52.9"
                     /tool="antismash"
                     /translation="PVILLHGLPAHSYIWRELLTSLEEYNINAIAPDWIGSGLSAKPDA
                     REFAYTPSAFCQALADFIQALQLPKISLIVQGFLASVGLQYALENPDKIERLIVLNTPL
                     SRDVKLPWIMKQWGLPFLGDMATQDPLLVDRTLETGSGFVISDANLAIFRQPYLKTSAV
                     GRALLATIRNLNLSKTMAEIETGLEHFEKPILFVWGMADPWLSSVTVEKL"
     gene            40231..40449
                     /locus_tag="LC603172_RS25935"
                     /old_locus_tag="MAN88_50330"
     CDS             40231..40449
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF016268.5"
                     /locus_tag="LC603172_RS25935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MAN88_50330"
                     /product="BrnT family toxin"
                     /protein_id="WP_239698208.1"
                     /transl_table=11
                     /translation="MQFREFDWDQSKRYSNIEKHGIDFAAVPPIFDGHCLIREDNRQDY
                     QEIRMCLLGQLNEIICYVVYTIRGETC"
     gene            complement(41194..42039)
                     /locus_tag="LC603172_RS25940"
                     /old_locus_tag="MAN88_50350"
     CDS             complement(41194..42039)
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002795280.1"
                     /locus_tag="LC603172_RS25940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MAN88_50350"
                     /product="IS5 family transposase"
                     /protein_id="WP_221275430.1"
                     /transl_table=11
                     /translation="MTYEKVKNLNPEEFKRFCGVYPETFKDMVKVLAAEKVLQKKSGRP
                     SKLSLEDQILMTLEYLREYRTYFHLAINWEINETTALRITRRVEGILMKSGLFNLPGKK
                     TVQQANSDLEVVVVDVAEHEIERPQKKQKDYYSGKQGYHTIKSQVLAAQKTGMIICTAH
                     GKGRIHDFNLWKNSQIGIDKSIECLADKGDQGIQKQHENSRIPYKKKKNQELSSEEKEF
                     NRQLSRERIIIEHIHRSLKIFRILSSRYRNRRRRFGLRFNLIAGIYNYELALGYHQVAE
                     "
     gene            42088..42269
                     /locus_tag="LC603172_RS29335"
                     /pseudo=""
     CDS             42088..42269
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002792302.1"
                     /locus_tag="LC603172_RS29335"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MDGGYKVCNPYIERHLAIFVNFFLI"
     gene            complement(42294..42638)
                     /locus_tag="LC603172_RS25945"
                     /old_locus_tag="MAN88_50360"
     CDS             complement(42294..42638)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="LC603172_RS25945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="MAN88_50360"
                     /product="hypothetical protein"
                     /protein_id="WP_061433175.1"
                     /transl_table=11
                     /translation="MWDRIRVKSLYIPLVLAAISSWKGNRLYLALDTTVLWNRYCMIHL
                     SIVCCGRAVPLLWRVLDHPSATVAVNTDKPMLRLAQRLLKDYPDVMLLADRGFANHGLL
                     SWRQVSGWHY"
     misc_feature    42775..42793
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 23.06"
                     /tool="antismash"
     misc_feature    complement(42807..42822)
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: weak,
                     score: 16.72"
                     /tool="antismash"
     gene            complement(42886..43134)
                     /locus_tag="LC603172_RS25950"
                     /old_locus_tag="MAN88_50370"
     CDS             complement(42886..43134)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="LC603172_RS25950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="MAN88_50370"
                     /product="hypothetical protein"
                     /protein_id="WP_155726781.1"
                     /transl_table=11
                     /translation="MSTTTSLYAQLLSLLCQHSQWRDLRHLKALAWMVTAVICSGKLSL
                     PMWESYVPSRATQAQSTERRWQRFMGNHRTHIPHPGR"
     gene            43244..43414
                     /locus_tag="LC603172_RS25955"
                     /old_locus_tag="MAN88_50380"
     CDS             43244..43414
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002802638.1"
                     /locus_tag="LC603172_RS25955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MAN88_50380"
                     /product="hypothetical protein"
                     /protein_id="WP_192846069.1"
                     /transl_table=11
                     /translation="MGIVNTKEERQDLTDWERVKSMSDAEIEANALSAPDALPFDDNWE
                     NAEIISPKIWE"
     misc_feature    43473..43485
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 20.68"
                     /tool="antismash"
     gene            43684..>44415
                     /locus_tag="LC603172_RS25960"
                     /pseudo=""
     CDS             43684..>44415
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002732125.1"
                     /locus_tag="LC603172_RS25960"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="IS5 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MFISKIMDYQNLSDEQFKRRFGVYKQTYRKMVESVKSVEADSNSP
                     SKRGPKPKLSIEEQVLVTLEYWREYRTYFHIGTSWELSESTIGRIVNKTEKML"
     misc_feature    complement(44524..44540)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 20.82"
                     /tool="antismash"
     gene            <44649..44783
                     /locus_tag="LC603172_RS25965"
                     /pseudo=""
     CDS             <44649..44783
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003744379.1"
                     /locus_tag="LC603172_RS25965"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="IS5/IS1182 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="LNRKLKILKILSCKYRNRRRRYSLRVNLLAAIYNCELGIGIAAS"
     gene            complement(<45012..45215)
                     /locus_tag="LC603172_RS25970"
                     /old_locus_tag="MAN88_50410"
                     /pseudo=""
     CDS             complement(<45012..45215)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611860.1"
                     /locus_tag="LC603172_RS25970"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="MAN88_50410"
                     /product="IS630 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MRPYSVDFRQKIIDVWKKEKISIRGLAQRFDVAKSFIQKLLKQHK
                     ETGDIRPRPQGGSPPTKLNSRTL"
     gene            <45285..45548
                     /locus_tag="LC603172_RS25975"
                     /old_locus_tag="MAN88_50420"
                     /pseudo=""
     CDS             <45285..45548
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012264517.1"
                     /locus_tag="LC603172_RS25975"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="MAN88_50420"
                     /product="transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="YITATQVCELLKKIAALGLTIPITLVLDNARYQKCKIVEELALSL
                     SIELLYLPSYSPNLNLIERLWKFVKKNVYSNSHSCEVQSLRF"
     gene            <45627..45785
                     /locus_tag="LC603172_RS25980"
                     /pseudo=""
     CDS             <45627..45785
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012264517.1"
                     /locus_tag="LC603172_RS25980"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="IS630 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="NAIYSKYYENFSDFSSAIY"
ORIGIN
        1 cacgcttggc aggactgcac ccgctcttta caacagcaat ccgataatta tctagcccat
       61 ttccatcggg gtttagcttt ttatcgtttg ggagattatc cacaggcgct gaccgattat
      121 aaccagacta tccagttaaa acccacctat tatcaagcct actataatcg gggtttagtt
      181 cagtcggcta ggaaaaatta tccccttgcc ctagctgatt ttaatcaatc cttgcgtcaa
      241 attactaact ggcaacccga cactttagcc actatttata atgatcgagg tttatctcat
      301 ttagccctcc acaattttac ctcagccaaa gcggatttta atcaagctct ccggttaaat
      361 aaaaataacg cttcagccta ctataatcta gcttgtaccg ctcaccaatt aggtgaatac
      421 gaacgctcga tcgcccattt aaatcgagcg attgccatcg atccttttta tgccgatgct
      481 tatattagaa ggggattact gcggcatcaa ttgggttatt atcaatcagc tttagcggat
      541 ttaaatcaag gagccaatca cctctatcaa cagggattgc accacaatta tcagcaaatc
      601 ctcgccctga tcgagcagat tcaccaacag ttactttcct taccatctcc cattgtttaa
      661 aagagtgatc aatattagac ctcttgcata attaattttt cagggttcaa aaacggcaaa
      721 aataaggatt aaatggcata aaatctgtaa atagaccatt taattgatta atgcttattt
      781 ttaattctcc tgactactga ctactggcta ctgactccta atcctaacaa cgatttttga
      841 tttctacaag aggtctatta taaaggaaag cgcttcatgg ctgtgacggc gagacgggca
      901 ttatctttaa ggacttggga aactcgggga atttggggaa tttgccagag aacatcgacg
      961 gtgcgccgta ataatcgcac tagatctccc tcatcgaggc tagtattttc gcacaattct
     1021 ggccaggatg tcccctgggc ccaacgggag gcaatcccca tcagttgggt ttctaaccag
     1081 acgggaatag tgatatcgta gcgagattga gcttgataga gtaaacggcg aacttctcgc
     1141 aggccggggg aatttccctc tccttgccgc aaaatatcga taacttctgg cacaggcggg
     1201 taattgcacc aagtatcggg gcgagggggt tccgtaatca tggcgctgat ggcggcggct
     1261 agttggctag gagtcaatct gtccaaatct ccggacatca tcgctaatcc taaccagagt
     1321 tcattttccc cgcgaatagt ggccgccgct tctccgaggg gagtgggcaa ataaccctct
     1381 aacgcttgga attctcgcaa aatctcgatt agattcagaa attcttccca gtagtaggat
     1441 ttacgggatt gttgtttttg gtatttaatc tgggctttgt ataacttatc gcgagcaatc
     1501 tctcgatcgt agtataattt catcaatcgc cccggatttt tgcgtttttg caggggatga
     1561 gcggcaattt gactattgac aatttcaatt ctttgtgcct gtgtttccag ttccaccacc
     1621 ggtgggatgc cctgcacttg ttgggggatg gaatcggcga tcgcctgagt attttcctca
     1681 cccttgcgcc accctcctag ggaaactgct gctagggaag ggggtatcag ttcgcctaat
     1741 tccgcaggag tgagaaaacc tcgatcgatc tcgctaatat cggcataggc ggctaaatac
     1801 cagcgattat cactgcctaa acaaacaaga gttcgcactt gaccagcgcc gtgcagggta
     1861 ttgacaaaga tagcggggac ggggacgggg accttaatat gtttgccctt gagatggagg
     1921 atagttccga cgggaatatt cggcaatttt agatgtattt cctgtctttt ctgtgcctct
     1981 gactgactag cgatgatttt atacagtctt tcttcctccc gcagtctttc ccgtagcttt
     2041 tcgtaactga agacctgttc ccgctcgata ccggctaact ccatatccaa cttagctaat
     2101 tcggtggtta aggcggtaat ctgttgtcgt tcggggctta acttcaaacg agcgagatat
     2161 tcggcgaaac tgcgctctaa gaggtctttt gcctgctcta gactgtgttt ttgcaggaga
     2221 tttaagacca tgccgtaact gggcgcaaaa cagctttgca ggggttccgg ttgggcggtg
     2281 gccagaaaag ccgcttcttt tgccccttca aagggcgttt gtactgtcac cacatggccc
     2341 accgcgtcca ttccccggcg acccgcccgg ccagcaatct ggacaaattc cgagggagtc
     2401 agcatactat ggccatcatc ggtgcgtttg gagagggccg agataacggt ggtgcgggcg
     2461 ggcatattaa tcccggccga gagggtagcg gtggcaaaaa ccaccttaat taaaccggct
     2521 tcaaagagtt gttcgactaa ttctttccag aggggtaaaa tcccggcatg gtgaacacca
     2581 cagccccggg tgaggggttc cacttggtcg gcgcgcacca attgggaagc actggccagg
     2641 aattcaaata gttgattttt cgtctcgggg tcggcggtta agaggctgag gagttgctcg
     2701 tcagactggg ggttattagc gaaaaaagcc agtaatttct ggtgtagggg cggattttcg
     2761 acggcaaaga aggaaagggc gagttcttgc agattgggat tatcttccag gaagaaaatg
     2821 agcaaacggt agtaaatggc tctagcttct tctggattaa cgaggttgag gttttttagc
     2881 tctcgaatcg cctgatcgca acctttgcgg ctgaaaatga cgtaaatggc tgggagcata
     2941 tccttgtccc gcagagtggt gacaatggag gcgatagtgg gacaatcttc tcgttttaag
     3001 cgtcggggtt tgccgtggcc gacttttgag cgtagtttcg ggttaacttt gctctgtttt
     3061 gggtcgagca gcgggaataa tccctcttta ttggcgaaat aaaagcgcag ggggacgggg
     3121 cgaaaatcgg agttaatgag atcgcagctg gaggtctgct gattgtcgcc gggttggggc
     3181 agttgccgca cccagttaat ccagtcggtg agttcccccg ggttgccaat ggtggcggag
     3241 agggcgacta attggatact agggggacag tagataattg attcttccca aacggtgccg
     3301 cgacctcgat cgctgatata gtgacattca tcgagaacca gggtttccac gttttctagg
     3361 gaagtgccta cctgaccgat cggggttttg tacagcatat tgcgaaaaat ttctgtagtc
     3421 atgactacaa ttaatgctga aggattgatc accacatcgc cggtaatcaa tcccacttcg
     3481 gcaaagagca gcggggaatc ctcatcgcca tcggtggggg tgcgaccgaa tttttcttga
     3541 aaatcccgga atttttggtt agaaagagct ttcaggggag tggtgtagaa aacccgtttg
     3601 cccctttcga gggcgcgata gatagcgtat tctccgatta aagttttgcc ggaacccgtg
     3661 ggagcgcaga cgaccactga tttaccggca gcgagagcgg cgatcgccga gtgctggaag
     3721 tcgtcgagtt taaagggaaa aatggttttg agattcaaag aagtagggtt aagggactct
     3781 ttcacgtcaa gtctaagagg agaaattttt ttaattgtgg ctattctggc tggctttttt
     3841 gattctagtc gaaaaaagcg gacttctaga aactagggac aagcttaacc tttgggggtg
     3901 atgcccaatc ccatcatact tcatttttat cagaaatgct gtaagctaag aggtatttaa
     3961 accgcttatt cttagattag ccgaatctct cccaatccct ttactgttga ctcttgcctc
     4021 ttgcctcgtc tcaacaagca atttaaatta cgaacagctt atcactaata attgtctctc
     4081 tattttctcc ttaacttgat tacttatact tactgatgat gattaatttt tctgctgaag
     4141 actgtctagt tttagtggtt gatgatgtca gtaaaaatct ccaattggct gtggagattc
     4201 ttgattctgc tggttatgcc accatttttg ctagtagttt taaacaggca atagaacaag
     4261 taaaaactgc taatcctgac ctaattcttc ttgacttaat gatgccagag atggggggaa
     4321 tagaagtttg tcgaagacta aaaactgaca atctatacgc tcatatacca attatctttg
     4381 tgacagatag taaggaaaaa gaagatattc tcaatgcttt taattctggg gctgtggact
     4441 atgtaaataa accctttcat agttgggaac tgttagccag agttaaaatt catctagaac
     4501 tgaaaaagac tcaagaagaa ctgaaaaata tcaattctca actagaaaag ctagtcagaa
     4561 ctgatagcct aactggggta aataatcgtc gagagattct ctacttaggt gagaaagaat
     4621 ttcaacgatg tcgtcgttat catcgttatt tttcggttct attcatcgat atcgaccatt
     4681 ttaaacatat taacgatacc tttggtcata tcctaggaaa caaaacttta attactgtcg
     4741 ctggggcaat taaaacctgt ctgcgtcaag tggatagttt tgggcgcttt gggggcgagg
     4801 aatttgtcgc tattctccca gaaactaatc ttgaagatgc tgctaccaca gcccagcgca
     4861 tttgtcaagt aattaacaag ttaaatattg aacttgctca acaaaaagtg ccagttactg
     4921 ctagtatcgg tgtggcaaca tttagccctc aagataataa tctagaagag gtgatcgagc
     4981 gggctgatca tgccatgtta gccgctaaaa atcaaggcag aaatcgagtt agtctaggta
     5041 aaacagtatg aaaaatttgt tatttattct tggttttttg ctcttaggtg tagccccaag
     5101 ttttagcgcc gatctcgata cgattatacg ccgaggaaaa ttaattgtcg ctgtcaaaaa
     5161 taatctccct cccctcgctt tccttgattc tcagggcaat ttacaaggat tggaaatcga
     5221 catcgctaaa cgtctagctg aagaaattct cggttctgac agtgctatta ttctcaaacc
     5281 cgttagtaat caagaacgtt tacaggtggt tattgatgat cgggtggatt tggcgatcgc
     5341 tcgtgtggcg attactcccg cacgtcagcg tctcgtggat tttagcccct tttattacct
     5401 cgatagcagc ggttttgtga cgaaaaacct gctatttcag cgtttagaag acctagctaa
     5461 ctctagaatc gccgtactca acggctcgac gacaatcgcc cttgtgcgtt cccatttacc
     5521 taaggctacc ctgcgcgggg ttgcttccta tcaagaagct ttaaatttac tggaaacggg
     5581 ggaaatagac gcttttgcgg ctgataatag ccttttaact ggttgggtgc agcaattccc
     5641 caattatcgt caattaccga tccagttggg tgcgatcgct ctaggagtcg ttctccctaa
     5701 aggtttacag taccaaagtc tccgagaacg cgtcaaccaa gcgatcgagc ggctagaatc
     5761 caccggctgg ttagtagaac gggtgaacta ttggggctta cccctgagaa ttcgggaaat
     5821 ggggagatag ggtgtggggt gtggggtgtg gggtgtgggg tgtggggtgt gggaagtggg
     5881 gtgtggggtg tggggtgtgg ggagtttttt gctgtgaaca gtgaacagtg aactgaaaac
     5941 tcacatctga gcggcgatca ctgataactg actaaatcct gctataatct gagggaataa
     6001 gtataaaaat attaattgct cgatcgctaa ttatggaaga taccctgccg cttatttacg
     6061 tttctggatt gctaattttc gtgattggtt taggaatttt tgtcatcgtg caaatcttta
     6121 aaacccgtcg agtggaagga acctttaaca agctacaaaa gaaattgcaa aaagaaaaag
     6181 gtacagctaa agaatactat gaattaggga gtctttatct cgataaaaaa ctctatgttc
     6241 aagctttgag tttactacaa aaggctttaa aaatctctga ggaagaaagc atcgaaccag
     6301 aaaatcaagc tctaatctac aatgcgctcg gtttttccta ttttgcccaa gaacaattag
     6361 aattagcgat tcgtaactac aaagaagcaa ttaaacttta tcctgaatac tcgatcgctc
     6421 tcaataatct tggcaatgtt tacgaaaaga aacaaatggc gaaaaaagct ctcgaaacct
     6481 acgaagaaac tctcaaattt gatcctaata ataccgtggc gaaaaagcga gcagaatccc
     6541 tgcgtaaacg cttcgctgaa tcgaaatagt tttgactact atcaaattct ttttagagat
     6601 cgaagaatct tcgatctctt tctttatttc aagccataaa acaccacgat taaaactggg
     6661 gttaaaatcg tcaaaattaa atttaggggc gcacccaaac gggtaaaatc gaggaattta
     6721 tagcctccgg gggcataaac catggtatta gtttgatagc caatcggtgt tagataacta
     6781 ttagaagcgg caaaggtgac agcatacata aaagccaaag gatttaaacc caaagttttc
     6841 gccacttcca cggcgacggg aatcattaac accacggcgg cgttattaga gagaatttca
     6901 gttaaaactg aggtaattag atagaagaaa actaagatcc aaaacccgga aagatgaccg
     6961 ccgatagcca ctaaattatc tgccaaccat ttagtcgttc ccgagttatc catggcagta
     7021 cccaggggaa ttaaacccgc taataaaaag ataatatccc aacgaatgga accatagact
     7081 tcccccggtt ttagacagcc agtaattacc attaaaacca ccccgactaa actggtgacg
     7141 agaatcggtt gaatatcaaa agcggcaata ataatcacca acaaagtaat cattaaagca
     7201 ataatgcctt tatcctgtcg caatgattcg atctcttttt cttctaagac taataattct
     7261 cgcgtggttt gtaaaccaat aaaactctgt tttggtcctt gaaccaagag caaatcgcca
     7321 aattttaaag gaattttccc taatcttcct tgcagtaatt ctgaaccacg ccgaatcgct
     7381 aaaaccgttg cgttataacg ctgacggaat ttcaaatctt ttaaagttgt cccaattaaa
     7441 cgggaattag agagaatcaa aacctcggct aatttttcct cacctgtagt aattgtcgat
     7501 tcaatatcta ctttctgaaa tttgacatcg gcaaagattt ctaagcctct ttcatcttta
     7561 atttttaata gttcttcccg actactgtga acgattaaaa tatcggcagc attgagaact
     7621 ttatcggcta aaggttggga taaatgtacc ttatttctga ttaattccaa cacatcaaaa
     7681 ttaaactttc tttgtagtcc actttgggat aaagtttgac cgataagatt agaacgaggg
     7741 gtaataatta cctcactcag atatacttta gaaccataat catcctctaa aaattccccg
     7801 gtggaagatt tgcgatcggg tagtaatttc ggggcaaaaa ttgttaaata aatcaaacct
     7861 gccaaaaaag tgactaatcc taaagcagtg aattgaaata agctaaattc cccataaccc
     7921 agcttggcag aaataccact agcgagaatg ttagtagaag tccccaccac ggtaatcatc
     7981 cccgctaaaa ccgtcgcgta ggaaagggga attaataact tagaaggaga aattttttgt
     8041 tttttacacc aatcttcgac gatgggtaaa aagatcgcca ccactgccgt gttattaata
     8101 aaagcactaa tcggccccac caatgcccct aagacaaata cctgttggtg gggatttttg
     8161 cccccccaaa ccagcaagcg atcgcgaatt acttgaatca ctcccgtgcg ggtaattcca
     8221 gcactaagca caaacatcgc catcactgtc accgtggcag aattactaaa tccggcgata
     8281 ccttcttcgg gagtaactaa acccaaaaga atcaggacaa tcgccacgca taaagcggtt
     8341 aaatctaccg gtagccattc cgccacgaaa gcgactaaag caacgactaa aaccgttaaa
     8401 gtcagaataa ttggtgttgg cattgattta ttttttcgtc atgaaccagc gaataaataa
     8461 cttctccaac tcaatccaaa caaacattaa ggcactaaat ccaaaacaga ttaataattc
     8521 tgtgccacta atccattgag tgccgaagaa gctttgtaga ggaggagcat aaattaacaa
     8581 caattgtagg atcgttgtca agcccacggc ggcgataatg taaggattag agaagggatt
     8641 catttgcaca gctaactggg tatgggaacg caccgctaaa gcgtgaccca tttgtgctaa
     8701 acagagggta gtaaatacca tggttttcca acgtccagga tctccgattt cgggggttgc
     8761 ctgagtatat tggtaagccc agtacatcat aataatggtg agaatggcaa agacgatgcc
     8821 gatgcgaatc atataccaac ccaaaccgcg ggcgaaaatg ctttcccggg ggctaaaagg
     8881 tggacgtttc atcacattag gttcggcggg ttccattgcc agagccagag ccggtaaacc
     8941 gtcggtgaca aggttcatcc agaggatttg caagggagaa aggggtacac cgcctaaacc
     9001 gagcagagga gccgccgcaa tggttaaaac ctcgccaata ttactgccga gaatgtattt
     9061 aataaagcgc cgaatgttac tgtaaaccac gcgcccttct tcggtggcgg cgacgatggt
     9121 ggcaaaatta tcatctagca aaatcatatc actggcttct ttgctgacat cggttcccgt
     9181 aatccccatg gcgataccga tatccgcttg ttttagtgcc ggagcatcgt tcaccccgtc
     9241 ccccgtcatg gcgacgaatt tgccccgttt ttgcaaagct tggacgattc tcagcttatg
     9301 ttcgggagaa acgcgagcat agacgctaac accatctacc tctccctcta ggtcattctg
     9361 agacattttt tctaattctt tacccgtgat tactcgctcc ccgggggcag caatgcctaa
     9421 ttcaatggcg atcgccttgg ccgttaattg gtgatctccg gtaatcataa tcggacgaat
     9481 tcccgcttga cgacagagag caaccgcttc tttaacttct ttgcggggtg catcgagcat
     9541 tcccaccaat cccaaccaaa ccagggattg ttcctcacta tcttctcttt ccgcttctgg
     9601 cacttctgtc atcggtttat aggaaaaacc taagactcgt aggccattac ccgccatttc
     9661 gtcattttgt gccaaaatac ggcttctttg ttctgctgtt aagggttgac tttccgcccc
     9721 aacttggatc agagaacaac gttcgagaat taattccggt gatcctttgg taaacattaa
     9781 ataggcagaa tcccccaaac ctaactgggc attctcacag attactgaca ttctctttct
     9841 ttcggaagaa aagggaaatt cgcctaaacg agggctttgt ggtgccaatg cttcccgata
     9901 tagtcctcct ttacccgcta acgtcagtaa agctccttcg gtgggatcgc ctaaaattga
     9961 ccattcttga gctttatttt gcaaaagtgc atcattacac agcacacaag ccgttaaaat
    10021 tgcctgtagt tcgggatcac tttcactagc accattaaac tcaccgatgg gcgcgtaacc
    10081 ttcccccgtg acagtaattg tctgctcgga ggtattaact ttctgcacca ccattttatt
    10141 ttgagttaaa gttccagttt tatcggagca aatcgtcgtt accgagccta aagtttccac
    10201 tgccggcaat ttacggatta aagcttgtct tctcaccatt ctctgggttc caattgccaa
    10261 agtcaccgtc accactgccg gtaaaccttc ggggacaaca gccacagcca tactgaggga
    10321 ggtttctaat aatgactcaa aaaactgcca accggagcta attacgcccc aaagcacgac
    10381 tacagccact aaagctaggg aaccactcac taaaacgtta cctaactgcg acattcgctg
    10441 ctgtagggga gttggttcac tttctactcc ttgcaacatg gcggcaattt taccgatttc
    10501 cgtatccatt cccgtcttgg taatcgccac tttcccgcgc ccctgtacta cttccgtacc
    10561 ctgatagacg aggttaatgc gatcgcccaa agaggcatct tccggtaaaa ccttctgtgc
    10621 ttgtttattc accgattccg cttcccccgt gagggcagct tcgcggattt gcaggttttg
    10681 tgcttctaat aacctgccat cggcagcaat ttgtaccccc gcttccagta acatgatatc
    10741 cccggggaca agttccttgg ctgtcacttc aaaggtgcta ccattacgaa taacccggac
    10801 tttgggcgag gataactgct taagggccgc taatgccttt tctgcccgac tttcctgtaa
    10861 atatcctaaa ataccgttta aaataacaat tgtaaaaata gcgattgcgt ctttgggaaa
    10921 ttcccctttt ttcaggtcca aaactgccga aaccaccgcc acggcgatca gcatcactaa
    10981 cataatgtta gtaaactgtt cccataaaat cattaacggg ctacgtcccc ccgtttcttt
    11041 tagttcattt aatccgaaaa aatcctttct tttaacaatt tccgcctcgt ttaagccagt
    11101 ttccccattg gttctcagga tttcgagggt ttgttctcca gttaaattat gccaagcacg
    11161 attattctct atctccgaga cttgaggtga cgtagtggga aaagtcatag cgatcgattg
    11221 aagagggtgt acgcgtgaac taaaaaggta agcgaattaa gctaattaca tatcacaata
    11281 tcagttatca gttatcagtg accagttatc agttatcagt gaccagttat cagttatcag
    11341 tgaccagcaa acagttatca gtgaccagta atcagttatc agtgaccagt aatcagttat
    11401 cagtgaccag taatcagtta tcagtgacca gtcagcagtt atcaaggaag tggggaagtg
    11461 gggaaatggg gaagctgtct catcacccta tcaccccaaa accccatcac cccaaaaccc
    11521 tatcacccta tcaccctatc tcctcctgcc ccctgccgac cgacttctcg ataatctgaa
    11581 aaaaaatgta acgaaatgtg aagtataata gcgaatgtga taaagacaag acattagaga
    11641 gtagatagga aacgatgcga gttgcgatcg ctggtgcggg actagccgga ttatcttgtg
    11701 cgaaatacct tgtcgatgcg ggacatacgc ccatcgtact ggaacgtcgc gatgtattag
    11761 ggggaaaaat tgccgcttgg aaagatgccg atggggactg gtacgaaacc ggtttacata
    11821 tcttctttgg cgcttatccc aatatgctgc aattattcca agaattaggc atagaagatc
    11881 gtttacagtg gaaagaacac tcgatgatct tcaatcagcc agaaaaaccg gggacctatt
    11941 cgcggtttga cttcccagat attcccgccc caattaacgg tattgttgcc attcttcgca
    12001 ataatgatat gttaacttgg gaggaaaaaa ttaaatttgg actcggttta atccctgcca
    12061 ttgttaaagg ccaaagttac gtcgaggaga tggataaata ttcttggtcg gaatggttag
    12121 agaaacaaaa cataccgcct agggtagaaa aagaagtgtt tatcgctatg tcgaaagccc
    12181 taaactttat cgatcctaac gagatttccg ccacgattct actaacagcc ctcaaccgct
    12241 ttttacagga gaaaaacggc tcaaaaatgg cttttctcga cggttcaccc ccggaaagac
    12301 tctgccaacc tttagtcgat tacatcaccg ctagaggcgg cgaagtgcgc ttaaacgccc
    12361 ctttaaaaga gattgtgtta aatgaagatg gcacagttaa agccttctta atgcgcggtt
    12421 tagacggtgg ggaagattat ctttttgaag ccgatcttta tgtgtctgcg atgccggtag
    12481 atcctttaaa agttttacta cctaaacctt ggcaagaaga taaattcttt caaaaattag
    12541 aaggattaga aggggttccc gtcattaatt tacacctctg gtttgatcgc aaactaaccg
    12601 acatcgatca tttattattc tcccgttcgc ccttactcag tgtttatgct gacatgagca
    12661 acacctgtaa agaatacgct aaccccgatc gctcgatgtt agaattagtt ctcgctcccg
    12721 ctcaggattg gattagcaaa tccgatgaag aaattatcgc cgccacgatg aaagaactag
    12781 aaaaactctt tccccaacat tttactggcg ataatcccag tcaattgtta aaatatcatc
    12841 tggtgaaaac tccccgatca gtttataaag ccacccctgg ccgacaagct tatcgacctt
    12901 ctcaaaaaac tccgatcgag aatttttatc tcgccggtga ctataccatg caaaaatatt
    12961 taggaagcat ggaaggagcg gttttatcag ggaaattagc ggcagcagtg atcagcaaag
    13021 atcaccccgc agcaccgcta aacccgaata aaacccaatc tataccagtg tccagcgctc
    13081 gttaattctc tggctaggga ctaatgacga aaatggcctt gagtgagaca atgctatatc
    13141 attagccaca gttcgccgtt aatctaagtc aatcattccg ccccagcaga atgctccaat
    13201 tgccaaaacc gacccacccc accaaacccc tcgtctccct tgcggagtcc tacgaactct
    13261 gtcgccggat tacagagaag tattccaaaa cgttttatct cggtactctc ctgatgccga
    13321 aagcaaaacg tcaagcgatc tgggcaattt atgtctggtg tcgtcgtacc gatgaactgg
    13381 tcgatggccc ccaagcccgg ttaactaccc ctgaaaccct cgatttatgg gaaaaacagc
    13441 tagaaaccgt cttttctggg gttgccatcg aggatgccga tgtcgctctc gtggatactc
    13501 tagaaaagtt ccccatggat atccaaccct ttcgggatat gatcgccggg caacagatgg
    13561 atctctatcg cagtcgttat caaacctttg atgaactaaa actgtactgc tatcgggtgg
    13621 cggggacggt ggggttaatg tccagcgcgg tgttaggatt ggaagatgac gatcgctcgg
    13681 ccccttggcg gcgcaatcaa agcgtctata tccctcaaga agaagcgatc gatctcggta
    13741 ttgccaatca attaaccaat attttgcggg atgtggggga agatgtccat cgtggccgga
    13801 tttatctacc tttagaggat ttagagcgtt ttaactacag cgaagacgat ttactcaaag
    13861 gggttaatga tcaccgttgg caggcgttaa tgcgcttcca aattgagcgc gctcgttatt
    13921 actacgattc cgccgaaagg gggattcgcg cccttaatcc cgattcccgt tggccggttt
    13981 gggcggcttt actgctttat caaggcattt tagacgtaat tgaagcaaat aactacgatg
    14041 tcttcgcccg tcgtgccttc gtgcctttac ccaagaaaat gctctattta cccgtggctt
    14101 ggctgcgatc gcaagcgtta taaaaattcg acgggttttg tcgcttaccg actccacccg
    14161 tcgagtctta actagggttg gctgaaaaag tctttcctgg gggcagggtg tggcccccca
    14221 acccccccga catcgggggg gcaggtgggg tgtagggttt tacctatttt catctggtaa
    14281 actacctaat tttcagggaa aaagtccctg aattctcccc ctgatcacta ccatatctgg
    14341 tactttttga cctcccaaaa gtctaaaagt cttacccaac aaggttttta gatttattca
    14401 gccaacccta actattaact gttcccaatt cagttgctta acttgggttt ggtttttcag
    14461 cgtgatttag gagtcaccaa ccagaaaggt ccagtttccg tgcagggaac atctcgttcg
    14521 gtttcgtaaa ccacaagacc ctcttgccga tccaaaacta acgcttctcc tagacggacg
    14581 taggatataa acgggccgag atagcggacg acaggctcat cgctacagga cggcaacacc
    14641 cgatcgttaa aatactcgta tcccacatcc tcgacgcttt catagtagcg gatgctgaga
    14701 tcatcgatcg ctttccccgg aaaacgttct tggatagctg accggagaaa ttctggcagc
    14761 ggtcgatcgg gcgataataa tgttgcagat ttcatggctt ttccccctaa aactaaagga
    14821 agcgggaaac tctgacaagt gcctccccca tcgggactat tcacttccgc tccccacccc
    14881 ggcaattttt tactagggat ggaagccagc gcggggagtt cccttgtatt cattgtaaca
    14941 aatttctccg caaaggttcg ggtcgatacc gtgagaacag gttctcttga tttttcgtta
    15001 caaagattga caaatttatc ctttcatttt agcgataata ataattacca ggcgacaagc
    15061 cagaacaaat agtggaaata gggaaagacg aacgaggctg ggactaacta actagcaata
    15121 atgatagcga gaaaagaagt ggtttagtag tgccgaattc tcgttcccaa ttatttagga
    15181 ggtaggaaag atgacaattt atgtcacccg cgagggggat aaactggtgg ccgattcccc
    15241 actggaattg gtggaaaaat tacaacaatg tcagggcaga atggcggaaa caagacagga
    15301 cttcatgact cggatggccg cacagatggt agccagccaa ggcgttaccg ttcctatcac
    15361 cgatccggag aattttatcg ccgagctaat ccacaacgat tttctcagcg tggtggacag
    15421 tattgatggc tgaaagtcgg ccggggaatt ggcaggaaaa cttagcccct agtaacccta
    15481 acactcaacc ccactaccct aggtcaaaaa gcaaaatttc cgagtcttct agagattgaa
    15541 tagccaaaga agtttcctcg ctaattgccg ctccatcccc cgctcgtaaa tgcacgccat
    15601 tcacggttat ttgccctcta gccacttgta accagccata acgactgggg gctaagggat
    15661 gggtgaggga ctggcctagg ggcaaaattc ctgcgtatag attaacgtct tgatggactt
    15721 taaccgcctt acctgcgccg gtgggagagg cgattaactg taaggtatgg ggagaaaatt
    15781 cgatcgcttt ttgttcatag ctgggttcta gattttttga gtcgggaata atccaaattt
    15841 gcagaagatg gaggggatta gtggcagaat gattaaattc actgtgtttt attcctgttc
    15901 ctgcgctcat ccgttgaatt tcaccgtgtc gaatcacgga acccgtgccg agactgtctt
    15961 ggtgttctag ttctccctcc aaaacatagg ttaaaatctc catatcgtgg tgtccgtggg
    16021 tgtgaaatcc ttttccccca attactttat cctcattaat aactcttaga ctcctaaaat
    16081 taatctgttg gggatcataa tattgggcaa aagaaaaagt atgataggta tccaaccaac
    16141 catagttagc gtggcctctt tcctcagctt tgcgtatagt aatcatcggt tttcctcttt
    16201 tttatctcta ttatattctc aaggcttttt gctagatcaa ctaaggatag ctgatgggtt
    16261 ttgttatccc ttttctgtca gaggagggat aggggagcat ctcacctttg caatgagcat
    16321 aaatacttag tggaaaaata ggcttttcga gggtaattct tgttttaatt ctccatgtac
    16381 gcagtcttta aaagcctcta tttcgttcca agacacgatt aagagtggct tttaggctaa
    16441 gtataattac ttatcgcgta agtgagatgc tcccggaggg aagggatagg aagtgtagat
    16501 agtcacggca agcgcatctt aacaatcctt gacaaaataa acctagaggg cgatttgggt
    16561 atatttgggt agaatttgcc ctctcaattg ttaagcaaca atcgaccaaa taggtcgatt
    16621 ttgtaactat tctgattgac tgctatcatt tgaaatgcct acacagcaag gggctgacaa
    16681 aattggcgaa ttgtcaacag cgtttgagct gcgcttaccc gggtaaatag tgtaataaaa
    16741 cttaataaat tatcctgatt gatgacttga caagaaaaat tattactgta aaattgcagg
    16801 aaagaatgta gttactcgaa ggagtttcag tcaaatgatt aatactcggt taaaacccgt
    16861 cactacgggt ctcattggtg ctgtgggttt gggggttgct ttattaggga tgcctgaaat
    16921 ggcggaagct gtagatataa aggcgggaat cgattatctt ttcaccccta aaggttcgga
    16981 cacatgggtt gatttcgatc gaaatggtcc gaatggacgt acatatttta aaggagttcc
    17041 tattttgcca ggagggactg atacggcagt aaaacgatta gatgactgcc atttcgacat
    17101 aaatggaaaa tgtactgtag gtcttcaatt tgtatctctt aatttggaga gtgttaaacc
    17161 ggtgcctgat tttggcaatc aaattgtatt tttaatgctg gatgatagtc acactcaacc
    17221 agtctcatct atgaccataa tggacattgg taataacatg gccacttgga caaacacatt
    17281 agacttttac tggaaattag tcgattcaga cagcaatgta ctcgcaactg gttttgagtc
    17341 ttttatcgga tcgggaaaag gaacttatgg ttcttcgtta cttggtatgg ttcgataggg
    17401 gggcataaat cgactaaatc cttatctggt aagagactta attgattagt tcgctctata
    17461 tcaaaaacaa ttaacaaaaa tcgctaaatg cctttctata taagggttcc atcccttata
    17521 acccccgtcc attgcataac acaaaccgaa gagccgaact tataatgacg acggccactt
    17581 ttctgttatc acttatgatg accaagcaga gtgggcgcgt cacacagata aaattcccga
    17641 accttcaact gtattaggct taattgccgt gggtttaagc tcaatagtcg gatttaaagg
    17701 caaaaaagag ccaaaataag ccttcgatcg cttctttttt accaagaaaa agccccccat
    17761 tgggggctga ggaagaatgt agttacttct tggagtatag caaatcatgt cgagaactgg
    17821 caaatatagc tcgatttttg tttattgttg cggtaaaaac gcctaactgt agcatttggg
    17881 cagattactt cataagttgc agttcagctg gcttgagcga gatttcaggt caaacttaag
    17941 ccaaatctcg ccaatctatc cctaaatctt gtaatttccg agccatcttt tctgccactt
    18001 cttcaggggt gggaacaagt ttaccttcag gggtaaaaaa gcgtaattgg ctgtcttgac
    18061 atcctcgccg ccctaaaagt gcggcgattc ctaaacctca cgatttaagt ttctgcttcc
    18121 accaccgtcg cataccacag ttaaaaaacc atgtactgtc ttacacagag tccacagact
    18181 ttcgccccat ttcagaagcc cgattccctg tgtcccacgg tacgttgacc gcctatagct
    18241 tcttgtactt gttgcgcgcg actttttacc cggccaagct tttctggtcg gaacccccta
    18301 agccgagttt tcaaggtgct gcgccgtcca cttggttttc gagactggcc ttttaattct
    18361 aacacctaga acggcggggt ttcagaccca aaatttccga tgaatcccta aaaataattc
    18421 taactgttga ctccataacc agccctgttc attcgctgca atttcttcgt attttcctgc
    18481 catcaactga aaccccttaa attctaaact ggtgagatca aaccaaaaat aattaggagt
    18541 ccggaaagtt tcctgataaa tttctttctt taaacctcta tcagtttctg ccgttgaatc
    18601 agacaaaatc tcgatgatga catggggata tttcccctct tcttcccaca ctacccaact
    18661 tttacgcggt tttcttgcta ctcccaaaac cacaaaaaaa tcaggacccc taaaatattc
    18721 tgattttcgt tgattagggc tgtaataaat agtcagatta ccaaaagcat agaaatcttg
    18781 gcggtctttc cataataact ctagtgattg gatcaaaagc atcaattgac gcagatgtaa
    18841 ctctgtttcc atagggggtt catcactcag taaatcactt ttgggaaaga taatttcctt
    18901 taactcatct tcaacaataa ccatgacgac cactcaatta tttaatcttc cctattttag
    18961 ctcttcagta gagcgttcta cggtttccta tcaacctaac cgtttagcag gattacgacg
    19021 ctttgccata gcgattacct ttctcaatat tttaggtcat actgtcctcg gatttgaaca
    19081 atcttgggcg caacctctgg tggctttagc aacaggttac agcgtagaat tattattaga
    19141 aagcgttgat gctagggtaa atggctttaa acctagatat ttaggaagta tcggtcagtt
    19201 tgtcgatttt ctgctttctg cccatattac ctcattagcg atcgctatgt tactctatgc
    19261 taatgagcgt ttatttccga ttatgtttgc agtagcggtg gctatcggat ctaaagcaat
    19321 ttttcggtta caagtggcgg ataaaacccg tcattttctc aatccttcta attttggtat
    19381 tagcgttacc ttactcttat ttccctggat tggcatcgcg cccccctatc agtttactga
    19441 gaatttaagc ggttgggcag attggatttt acccgtctta attgtttgta cgggaacgtt
    19501 tttaaatgcc cgttttactc gtaaattgcc tttaattgcc ggatggttag gggcttttat
    19561 cttacaagca atccttagaa gtgctatctt tcacacagcg ttaatccccg ccctattacc
    19621 catgacaggg gtggcttttg tcctctttac cttctatatg gtaacggatc cgggaacaac
    19681 accgattaac ccccgtgagc agataatttt tggggcatct gtagccgttg cttatggcat
    19741 tttgatgtcc tttcatgttg tttttgggat gtttttcgga ttgacactgg tgtgttgttt
    19801 cagagggttg atattagcgg ttgaaccctt aaaagcaaaa ttacccctag tacaggcttc
    19861 cggcatttta tcaactcctt aaccaatata ttatgcggtt tttgtgggca aagcccaccc
    19921 tacagctttt agctacaaac tacaaatgaa aagggcgtaa gtcttacgcc cctacagtaa
    19981 cattctcctg gtcattgact atgaaagctt ctcctcaaat tgctattgtt ggcatggctt
    20041 gtctttatcc tgatgccgat tctccacagg aattatggga aaatgtcctg tctcagcgtc
    20101 gggcatttcg tcgctttccc tcagagcgat tatcgttaag tgactactat tctcccgata
    20161 aaagcacccc cgatgtcatt tattcgactc aagctgccgt tattgagggc tatgaattcg
    20221 atcgcattgc ttataaagtg gtggggagta cctttcgttc ggctgattta gcccactggt
    20281 tagcgttaga tattgcgtct caggcgttga atgatgccgg atttcccgac ggaaaggggt
    20341 taaataaaga aacaaccggg gttttactgg gaaataccct cacaggcgag ttatcgcggg
    20401 ctaataccct aagattgcgt tggccctatg tgcgtcatag ggtagaagaa caattattaa
    20461 aacaaggatt atcggacaaa gaacggcaaa ttttcttaaa tgaattagaa aatcgcttta
    20521 aagaaccctt tgaaccgatt ggagaggagt ctttagcggg aaatctctcg aatacgatag
    20581 cggggagaat ttgtaattat tttgacttaa aagggggtgg atatatcgtc gatggggctt
    20641 gtagttcctc tttactggca gtagcgaatg gttgttcggc tttagtcgct gaagatttag
    20701 atatcgcttt agtcgggggt gtggatatta gtatggaccc ttttgagttg gtgggttttg
    20761 ccaaaacggg ggccttagcc tctggggaga tgaaagtgta tgatcaaggg tctaatgggt
    20821 ttattccggg ggaaggatgc ggttttttgg tgttaatgcg tcatggggat gccctagccc
    20881 aaaataaacg gatttatgct gttattcagg gttgggggat ttcttccgat ggcaaaggcg
    20941 gaattactcg cccagaagtg gaaggacagt tattggcttt aaatcgcgcc tataaacggg
    21001 ctgaatttac gggggatact atagcttatt ttgaaggcca tggtacggga acggcggtgg
    21061 gtgatggaac cgaattagaa gttttatctc gtattcatcc agatacggta aataaagccg
    21121 ttattggttc aattaaagcg aatattggcc atactaaggc agcagcaggg atagcagggt
    21181 taattaaggc gactatggcg gttcatcgtc aaattttacc accggtgacg ggatgcgatc
    21241 gccctcaggc tcagttaacc gaagacaagg caagattaca ggtattaaaa gaggggcaaa
    21301 tctggccaaa ttccttacct ttacgggcag cagtgagtgc catgggtttt gggggcatta
    21361 acagtcatat tatcatcgag ggattaagtc agattcgtcg tcacactcta acaccacagg
    21421 aacaaaaatt aatccattct ccccaagatg cggagttatt cctattgagt gcaaatcgtc
    21481 aagaagactt acaagcacag gttaatcggt tattaaatat tgttcctcgc atatcccagt
    21541 cagaaatgac ggatcttgcc gttgaattag cgaaaaaggt caatcctcat ttaccctatc
    21601 gtctggccat tattgcatct tcccccgata gcttaaccaa tcagcttgta ggagcgcaag
    21661 gcttgcactc gttgatcccc cccggtcaaa atttagataa tatctttacc aataacgaaa
    21721 aacagatcaa taaaataggt tttctctttc cggggcaatc cgcaccagtt tatcttcatg
    21781 ggggactctg ggaaagacgt tttcctgtga ttaaacaatt atataacaag gctcagttag
    21841 ccaagggtaa ggataacacg gtgacgaata ttgctcaacc ggcgatcatt acggcttgcc
    21901 taggggggtt acaactctta gaaaacttaa atattaaagc agatttagcc ataggacaca
    21961 gtttagggga attatgcgct ttattttggg caaatgccta tgataagact caattaatta
    22021 atctagctaa aattcgcggt caagcaatgg cacaactggg ccacccaaca ggtagaatgg
    22081 ccagcattaa cgccgatgca gaaacggtta aaagtttatt aaatggacgt atcgttgaga
    22141 ttgcgggatt aaattcaccc tatcagacaa taatctcagg agaggcatta gggattaaag
    22201 atgttgttga aaaagcccaa aataaaggca ttaaaaccgt ttatttgcct gtctcccacg
    22261 ctttccattc tcccctagtg gcccgggctg tgcaaccctt agaagattat ttacaaactt
    22321 atcccttaaa ttccctggaa aaaacggtta tttctaccgt aacaggcgaa aaattgccat
    22381 taaataccga ctggcgctcg cttttgttag aacaaatcac ctcaccggtg cgcttcatcg
    22441 atgcagtcaa gtcagcagag aaagaggttg atttattcat tgaagtgggt tccggttcga
    22501 tattaagccg tttagtggca gatataacgg atattcccgt aatttctctc gatagcagca
    22561 gtgagtcttt acaagggtta ttgaaaacgg ttgcagtgat gtttgttaat ggtgtcaagg
    22621 ttaactatca agggttattt gaagatagat ttagtcgtcc ctttaattta gactatcaac
    22681 cccattttat tgccaatcca tgtgagatca aggtaaaggg caaaagtcaa caggcaaaag
    22741 tagagaatat tgctctttta ttgcctaatc atagccaaaa cctcaaacct gaaacctcaa
    22801 aaattgaagt tattcgtcaa ttagtcgcac aaaaaacaga attaccccta gaaaccattg
    22861 aaaatcatca tcgcttgttg gcggatctgc accttaattc tatcagtgtc agtcaattag
    22921 tgatcgaagc agcgcgtcag ttagacttat ctcctcccca ttcaccgaca gattatgcca
    22981 atgcaactat tcaggatcta gcagcagctt tagaagaatt aggcaaaaat aatccccaaa
    23041 ttcctcaaga atcaatccct atgggtgttg ataattgggt gcgtgcgttt acggttgaat
    23101 taatcgaaaa accgttaatt aaatcagata aaaagcaaat aaatcgagaa aaagcgggaa
    23161 attggcatat tatcgcccat gctgatcatc ctttattacc taacttatct gttttacaac
    23221 ccaccttaaa gcatgagcag gaaaaaggga ttattatttg tttaaaatcc catcctgatg
    23281 aatcagaaat cgatttgctt ttaaaagggg caaaattatc tataaaagag aaaaaaccct
    23341 tgattttgat tcaacaagga ggaggatatg cgtcctttgc gagaactttt tatctagaaa
    23401 atcgtcaaat tcccacctgt gtgattgata ttccttttca tcatcccaat gcagttaata
    23461 tcattctctc agaaatcact gcaaccgata gctatacaga agtttattat gatgaaaacg
    23521 gaaaacggtt tgttcgtcaa ttaaacttgt tagggttaga aaaagatacc gataacccta
    23581 agcagaaaaa agccctaaaa agttcaaata aaagcaaaat caaggagctt cttttggtga
    23641 cggggggagg gagaggtatt gcctcagaat gtgccttatc cttagctaaa gaaaataaag
    23701 ctaccttagc gattttagga cgttctcaac ctgaagataa ccgagaatta gccgaaaatt
    23761 tagcaagaat gaagtctgca aacatccaag tccattatta ttcttgtgat gtcagtgatg
    23821 ctgagtcagt tcagcaaact atcgccgaaa ttaagacaaa tttaggagaa attacgggaa
    23881 ttttacacgg tgcgggggtt aatacaccga aattaattca acatctcgaa ccagaagatt
    23941 tcctagcaac tttagcccca aaagtcaagg gtttgcaaca tatcttaacg gaaattaacc
    24001 ccgattctct caactattta atcaccttcg gttcaattat tgccgaaact ggattgaaag
    24061 gagaagcaga ctatgggtta gccaatgaat ggttagggga tattgtagcg gaatttagtc
    24121 aaaaataccc taattgtcgc tgtttaaacc tagaatggtc ggtttggtcc ggtattggca
    24181 tgggagaacg tttaggaaca gttgaaaagc taagaaatga aggtattacc cctatttctc
    24241 ccgatattgg cattaaatac ttacatttac ttttaaatca atccctaccc actgcctctg
    24301 tcatcatcgc cgggcgtttt ggtgaaccgc cgactttaag cttaaaaccg caagaattgt
    24361 cttttttacg ctttttagag acaaagaaag ttcattacac gggaattgaa ctgattactg
    24421 aagcagaatt atccttagac aatgatcctt atttacaaga tcatgtttat caaggagaat
    24481 acattttccc cggtgtcctg gggttagaag cgatcgcgca ggtggccact gcattactcc
    24541 ccaccttagc aaggaaggag gatcaaactc ttaacaaggg ggaaaaccaa gatccccctt
    24601 ccgtccccct taacaagggg gaaactggag gattaaggtt tgaatcggtt aaatttaacc
    24661 gtccgatcgt ggtttctgcc gataaaccat taaagataca aattgctacc ttaatcaccg
    24721 attctggaaa ggttaaggcc gttattcgct gtgccaatac agggtttagt atcgatcatt
    24781 ttgaagccat catcagccat tcttctgtgg gggcgccaga ctgtcgccca ttgattcccc
    24841 ctgtccccct taaagaagga aaaaataacc ctcaaattaa tccagatacg gacttatatg
    24901 gtcatttatt gttccataaa gcaagatttc aacgaattaa gggttattct catctcaaag
    24961 caaccgaatg tattgcagaa attaacattg agccaaaaac tgcttggttt agtcgttatt
    25021 tacctcaatc cctgatttta ggcgatgcag gggcaagaga tgccgttatc catgctttac
    25081 aagcttgtgt tccccatgcc actattttac ccactggcat agaacgctta acggtatatt
    25141 ctgtcaattt aggcgaaaat cagtttgttt cagccaaaga aagactgcat caaggagata
    25201 cctttgtcta tgatcttgag gtattggatg acgatggcaa tctcttagaa gtgtggcaag
    25261 gattggaatt aaaggtgatt aaacacagaa atcctcaaga tccctggatt ccagcccttt
    25321 taccctgtta tttagaacga aagattaagg aggtgatgcc taatgtcgat ttaactttaa
    25381 ttctcgatcg ggatgcaacg gtagaaagac gagtcagaag cgatcgcagt ttagggatgt
    25441 taacctcatc ccctagtgta attcagcgtc ggggggatgg caagcccgaa ttaagcgata
    25501 acgagacggt ttcggtatct catgccgaag atttaaccct tgtgcttaag ggtgcgtcag
    25561 gatgcgatct ggaaccgatt atcccccgtg atgtgcagat gtggcgcgat ttattggggg
    25621 aaaattcctt taatttagcg gaggtaatta gtcaagagaa tcatgaggat tttaatatgg
    25681 cagcgactcg catttggtct gctaaagaaa gtattaagaa agcgggtttg agtctcgata
    25741 tcccgttaac tttatcgtct ttctctcaac aattaacccc tttatcccct attttgtggt
    25801 tatcttcagg aaaggattta atcatcactt tacctgtttc tttccgagaa atcaagacag
    25861 ctttcatctt ggcaatattt gtccaaacag ttccagaaaa atcggactta cttcagacag
    25921 aaccattaaa gtttttctga taaaaattat ccagttttac catttttaaa accacaggag
    25981 aaccaaatca tgactacagt tcgacaaatt cccaaccaaa gaaaccctat tcaactgatt
    26041 tcaaatatca tccgttcttt cgtttatgcg atgaatggac gctggcataa attggggatg
    26101 caaatcttta tgatagtgac tattgcccac atatcagaac atattattca agcttatcaa
    26161 ttgtgggttt taggatggcc gagaccagaa tgtttagggt tattaggact ctggaaacct
    26221 tggttaatgc gctcggaatg gctacactat ggacacgctc tttttatgtt attagggtta
    26281 gctatttttc gtccttcttt tcatggaaaa gctcgtcttt ggtgggattt ggctttagga
    26341 ttacaattct atcatcattt tgaacacgct ttactcttag gacaggcaat tattggtcaa
    26401 aacttatggt attctcctgt aagaacaagt atcggacaaa tttggtttcc tcggttagaa
    26461 ctgcatcttt tctataactt aatggttcta attcccatga tgattgccat gtattatcat
    26521 cgttttccac ctatgaatga ggggagatta gtttaaattt cagccaaagt taaagaaagt
    26581 attaggaaaa tgggggtaaa tgagtattta ccctattcct ctagttaatt gtgctgaaaa
    26641 gttgtctcta gtccttaaaa aaggcatgat tgctctcctc ctcgtattaa ttaagataaa
    26701 gagtcattaa ctatctgttg aaattcctcc aatgaattaa tagtaatact gggaacaaaa
    26761 agactctcta agacagacac atcctcaatt tggttaatcg tttcaatcag ggaattagga
    26821 atctccccaa aacgactttg taaagccaaa atgatatgtt tttggttagt taatttagct
    26881 cctgatttag ctccttcttc gagggccatt tcttctatgg tgcttaaaaa aggcatgatt
    26941 acgctccttc tcatattaat taggataaag agtcattaac tagctgttga aaatcctcca
    27001 atgaattaat agtaatactg ggaacaaaaa gactctctaa gacagacaca tcctcaattt
    27061 ggttaatcgt ttcaatcagg gaattaggaa tttccccaaa acgactttgt aaagccaaaa
    27121 tgatatgttt ttggttagtt aatttagctc cttcttcgag ggccatttct tctatggtgc
    27181 ttaaaaaagg cattttgttt tcctcctcgt attgactgag ttttgtttta aagttaagtt
    27241 gaagttgcgg gggtaaggtc atcattttat caatgaattt ccctagattg ataatctcaa
    27301 acttggttaa tcccctttga tataaacctc tgactaagtt ccacttccat tgttcacgct
    27361 ccctgagatt attagtcgta gccttagttt ttaggtgtgc catgactatt atagcccaaa
    27421 tattctcact ttgttctaag tcttcccatt gataatccaa taatttgacc attaaaaaat
    27481 cgactctcac ttgacttccc cctaacccat attgataaaa atccggtcgc caagacctac
    27541 tttcatcccc taaaatagct aaactaataa cgggtttatg gtacaaatca aaggctcgat
    27601 aattataaat aaacattcgt tgagggaatt ttagatcata ttgactttgg acttcaatat
    27661 gaattaaaag ccagatttcc tgattatcta ataaccaaac tttcaataat ttatcagcat
    27721 agcgttgctc agtttccgca gctgccgtaa ttttttctaa ttctttatca agggaaatag
    27781 gggtttgatt ccagtcaatt tcttgataaa tattgggata aaagaagctt aagaactctg
    27841 ccaaataagt gctaatcgct tctttccatg ttttgtcgta attagctgtc acctcagcca
    27901 tgcctttccc acctaattgc tatataataa ataatatcct aatctttcaa aaaaaatgga
    27961 caattctaac cctactccta tcccctgcga aaatagtgat atttcttcct tagaaaccgc
    28021 taaccacaaa cccttttgga aagccattgt ggaaattggt gaaaaagttc ccattgaaga
    28081 gtggaacaaa ttacctaaag attttgctcg caatgcagag cattatatgt atggcgcacc
    28141 cagagacgaa gattacgagg aagaatgaga aagatttttt tagatacctt ctatcttcaa
    28201 gcattagctg attatcaaga taacgctcat caaattgctt tgaatatgac tgacaattta
    28261 ggtaattttc tatctgttac tagcgaaatg gtgttaaccg aactactcaa tgccttatct
    28321 ggaaggggtg ggtatttaag ggatgctgcc ctagacattg tggataaatt acaccaagac
    28381 ttatcggtag aaattatccc tcaaacctct cagttatttg ctgaagcatt gctattgtat
    28441 cgccaaagac aagataaaag ctatagctta acagattgtg cttcgatgtt gattatgaga
    28501 caacaaaata tctccgatgt tttaactttt gatcgccatt ttcaacaaga aggatttaat
    28561 gcactactga gaaattagga ggtaaaataa ctaattgact ttttgagcta cttctgctag
    28621 acaatcaaag tgacgaccat atttaacaat aatcgtcatc gatcctcgat aatcaattaa
    28681 ccctgtcatt accgctttaa ctgcaccaat ttcttgatta acaaatcgtt cccaattttc
    28741 tctagttgct gaaaaaatcg gtaaagattc atccatttct tcaatcagtt ctaaactaac
    28801 aatctgaccc tgatcatccc attctgaaca aacagaaacc ccctgatgat cactaaacca
    28861 aagaattact tttcccaatt tagtgaactt tttacctaag ttttcttgtt cgttccatgt
    28921 cgtttgatag gcagaccacc attcttgaga aaaacgagtt aacggttgat tcatgaggta
    28981 taatcagaaa ataaaaaact tgtgtttagt ttatcattat caggataacc tatgatcatc
    29041 ttaaaattcc tactttatgc ccctcagggt aagcgcatct taacaatcct tgacaaaatg
    29101 aactttatat ggtttgccta cccagagcgc ggttcagaca tatttgagta gaatttgtca
    29161 tcgcagttga gatcataact attctgattg actggtatga ttgcaaatgt gtagaggaca
    29221 agcagctgac aaaattggtc aattgtcaat agcgttcttt taaaaccgtt gttaatctcg
    29281 aaaaatcgct aaatagtcat tatgaaagcc tacgaatatc atcacattgt cagttttcaa
    29341 gaaactaact tagtcggtaa tgtttattat gccaattatg tgcaatggca aggtcgttgt
    29401 cgagaaatgt ttctcaaaga taatgcccca gatattatca cagaattatg ccaaggatta
    29461 gccttagtaa cggttcgagt atcctgtgag tatctgtccg aattatttgc ctttgatcat
    29521 gttattattc ggatgcgttt aggagagatt aaacaaaacc gaattaccat gttatttgaa
    29581 tattggcgag tgactgatga aggtgaagaa ttagtagcaa aaggggaaca acaaacagcc
    29641 tgtatgcgac gagaggatgg tgaaaccaga cccactccaa ttcctgctca actgaaatta
    29701 gctttagaga actatcacat cccgatctaa aggataaccc gaggaatgtg agataaaaat
    29761 aaccgataaa aaatgactct cctagactgg ttatagccaa ttagtggttt aaatgagctt
    29821 aacccgaaac ttccgcagct ttcatttatc ccagtatgag ccgactcctg ttgaggcggc
    29881 ttgcctagat gaccacacta cccgtaaacc ttttcaaaca tactctaaaa aatatcggca
    29941 ggatcggcat attggagctt attaatagcc gtggctccag caatcaagga catgagcaag
    30001 gttaaaccaa agacgaatat tgctctagta ggggtcattt caatgggaag taaggtgtat
    30061 ttttgggtaa aataatactg aatcatccct aataaaaagc caggaatata acccaatact
    30121 gcaataatca gagcttgctg aaagacgagc cacagaagat aacgattgtg atatcccatt
    30181 gcttttagag ttgcatattc tgctaagtgt tctgcaacat tggtataaag aatttgataa
    30241 acaaccacaa tcccgaccac taatcctaaa aatacaccca aattaaaaat aaaaccaata
    30301 gctgtactgg ttgcccaata atttttttca aagttaataa actcttgctt gcttaatatt
    30361 ttgacatctt tcggcaaata tttctttaac tttttgagta aggattgccg atcaatatct
    30421 ggttgaaact taattaagcc aatatcaatg aaccgagatg aacgattctg aaatattctt
    30481 aaaaagttag ggtagctcat taataagtta ccatctgaac caaaagatgt acctaattca
    30541 aagagaccaa ccacttctat ttttcgatta ttaccagaat ttcccacctc agtaataata
    30601 gttttaccct tctggaaatc ttcagcaata tttccaaact ctctacgaga attttggtca
    30661 aataaggtgg tatattttat ctttaatttt tgccaatttt ctttgattcc caccgcctta
    30721 aatgcttgat atcttaaatc aattccaatt acaaaaatat tacgccaata gttttttgta
    30781 tcgggatttt tccattgagc atagcctaca tagattggac tgactaattc cacttcatta
    30841 aaggataaga cttgtaatag tcttcgctca ctaaaacttt ccatggcaat taaggatgta
    30901 gaacgaggac taatcaggaa agcatcacct tctaaactat tatgtaaatg aacagcactc
    30961 tcaaataaag catctcgaat tcccaactgc ataaaaataa ttacagtgga aaaaataata
    31021 ccagatagtg caacaattaa acgagttctt ttatgagcta attgtaacca agcagtggga
    31081 atattcatct tctgaatgag ttatttagtt aggatgaatg atcacattaa cctttaagtt
    31141 agttaaccga ttaactttag cactagagcg atgatctaag ctaattttta cctcgacgac
    31201 tctagcatct gtatcgacaa caggatcggt tcctaaaaca tcttgtcgtc ccactttcca
    31261 acctatttct tccacagttc cctctaaatc tccgagcatt ttatcggttt ttatcgttac
    31321 agattgacct aatttaactc gactaatatc cgtttcatac acttctgctg tcacatacat
    31381 tttttggatg tttcccaaat ctaaaattcc ttcatttttc actaattctc cgggaaaagt
    31441 atgaattttt aaaattcttc ctgcatgggg cgcacgcaca taggataatt ctaattccgc
    31501 ctgagcgcgt tctacattag ccttagctgt cattacttca tcttgagcaa tttgaagatc
    31561 aacaggacga atttccgtaa ctgcacttaa catagcttgg ttttcttgaa tttgttgttc
    31621 taaagtatta agagttcgtt gtagattggc tctggcttcc tgaatttttt gttctaaggt
    31681 agtcgtaatg cgttgcaagt tagcctcagc ttcttggagt cttttttgtg tagttgtcgc
    31741 ctctaaacaa aatcgctctt tttccccttg agaaactgca ccattacggt ataaagattg
    31801 ataacgttga caatctgtga gagaattatt caattctgct ttaattcttt caacggtagc
    31861 tttttgtcct agtttttccc cttcaagttc cgattccaaa ctagagatcg ctgctgtttg
    31921 cctcattatt tgtccctcta attccgcttt gctttgacgc atacgggaat cttgagccat
    31981 aatttcgcct ttttttgccc cttctctcac tttttcgagt ttagatgctg ctaaacccag
    32041 atttgcttga gcttgtttca gggctgctcg caaacgggca ttattatcta aaatagccat
    32101 aatttcgcct ttttcaactt tttctccctg ttttaccagt attttatcta ctctacttcc
    32161 ttccaaaaag gcagtagctg atatttgagt aattccacct tggggttcaa gataaccaag
    32221 ggcagcaaca gcttcgggag tatcaggaga aaccgtcggg gaaatcgata actgggaagc
    32281 tttcaaggat gattctggtc taaaatagaa gataataacg gttgttccca agctaaatcc
    32341 cataaaagct cctaaaagac cccaaaacca atattttaaa gaataggaat tttgaaggcg
    32401 aaagttagcc attgttgtta acagggataa ggattcatca aataaacttt gtttaaggta
    32461 acatgaggtc atatcttcgg cctcccatca agggttgtca actttgtcaa ctttttttaa
    32521 caatggcatc taatttctca ggcgcaccct tcgagcatcc tgctgtcaat tttgatcaca
    32581 aattttctcc taggcaggta aatcgttttc cacaacgatt gttgctcctt tcaccccaag
    32641 cggcaacctt taatcagcgt ggattcatct gtgatccgca aagccgcagc ccggctgctc
    32701 agcctcaaaa acagatatat ttggaaacga tcgggcaaac ttttatctat ggctataatg
    32761 cagcaattat ggctcattct ctcacggact tgtttcctct tcttgaaggt gtcacgctca
    32821 atttgagagg atttgcttat gaaggggcag cgatggcttt atctttgcta gattgtttaa
    32881 ccctgggtaa gcgcgatcgc tttgagcatt ttttagcaaa cgaggggaaa aagcatattt
    32941 acatggccta tgtaggtaaa ggatggcaat tagcccgtat tcctttttct ttgcgctttt
    33001 atctccaaaa attagaacat tctgcccaac attttccaga ttctctatta gggtggttag
    33061 cccttgacgg ctatggattt catcagggat actttgcctg gcctaagtat atccgagaga
    33121 gaaagtctcc tcaagaatta tcgggttatg cgcgtcttgt ctttgcccaa gggttagggc
    33181 gcagtctttg gtttgtgaaa ggggcaaata ttcccgaaat tgccgatcag atccaaaaat
    33241 tcgacccgct gcttcaaccc catttatgga gtgggatcgg cttggcttgc acttatgcgg
    33301 ggggagtgtc tcccgaagaa attcaacatt taaaacagct ggctgaacct tatagagcag
    33361 aattagccca gggagcagct tttgcggcaa aagcacgttt actagccgaa aactgccagg
    33421 aaaataccga aatagcctgt caaattttgt gtggaatggc tattactgaa acagccaaga
    33481 tcactgatga taccctcatc ggcttagatt accacgacca aatccctgcc tatgaacaat
    33541 ggcgacaagc catccaaagt cattttcgca cctaatcccc taaactgtct taagcttaga
    33601 ttgaatgtag ttacttcttt gaaaccatga atcgtttgga aaaattcatc cgacgccata
    33661 gtaagtctat cttggcattg gggctaattt tagtcttatt ctttgtttcc cgtctccccg
    33721 ccctatcaat ggccgaaaga gatgcgatcg cttctcgctt tgcctttact cgttttccct
    33781 tacctgaatt agaaaatcaa ccctatcaag tagaaagacc gacaaatccc agtttaagcc
    33841 gtcattcggc ctggatttcg gcagttgggg cggcagttgc cctgggggat ctcgatggag
    33901 atggcttgga taatgatctc tgtcatgtag aaacccaaag caatcaggtg attatctccc
    33961 ctgttccggg tacgggcaat cgttatcagc ccttcaccct gaatgtcacc gattttgact
    34021 ataacgacca aaccatggcc ccgatgggat gtattcccag tgatctcaat gaagatggac
    34081 tcagggatct attagtgtat tattggggac gaacaccgat cgcttttatc aagcaagatc
    34141 aaggttatct tcagcagcaa atcagccaaa aaagggaaaa atggtacacc aatgcagcaa
    34201 ccttctcgga tttagatggg gacggacacc cagacttaat cattggcaat tacttcccag
    34261 ataatgccga gattttggat gtcaattctc agaaaatcga gaaaatgcaa gattcgatga
    34321 cccgtgctta taatggcggt aaaaatcgag ttttcttgtg gtccgatgcc tctaccactg
    34381 gagtgactta tcaagaagtc caagatgctt ttgaggagaa aattgctcat ggttggacat
    34441 tggccgtcgg aacagccgat ttagacgggg atttattgcc agagatttat ttggccaatg
    34501 atttcggacc cgatcgcctc ttacataatc gctctactag aggacatctc caatttgcct
    34561 tactggaagg gcaaaaaggt ttaacgacac ccaattctaa ggtactcggt catgatggct
    34621 ttaagggaat gggggtagat ttcggagata ttaaccatga tggactccta gacatctatg
    34681 tgagtaatat tgcttcggaa tacgccctag aggaaagtca ttttctcttt accagtacgg
    34741 gagaaacgga gaaaatgtcc cgaggaatcg ccccttatgt cgataaaagc gaacccttgg
    34801 gagtctctcg tagtggctgg agttgggaaa caaaattcgg cgattttgat aatgatgggg
    34861 agttagaagc gttgcaagcc acaggatttc gtaaaggtga catcaatcgt tggccggaat
    34921 tacatgagtt agccatgagt aatgatcaag tcctgaaaat ccccaatagt tggtttcatt
    34981 tccaagatgg agacgattta agtggtcatc aacataatcc cttttttgtg cggggtaaag
    35041 atggacgtta ctatgatttg gcatcgcaat taagcttaga tgatccctct gtcaccagag
    35101 gaatcgccac cgccgatgtg gatggagatg gggatttaga ctttgtagtg gcaaatcagt
    35161 gggaaacctc ttatttttat cgcaatgata gtccaaatat cggtcaatct ctggaattag
    35221 agcttttaaa ccctgcgctc tcccctaatc cctcttcaga aaaggggaaa atgggtatcc
    35281 ccgcaattgg cgcagcggtt aaggtgtctc tacctgatgg cagtcagctg gtggcgcagg
    35341 tagatggggg caatggtcat tctggcgtga gaagtccagt attacacttt ggtttaggca
    35401 aaattgaccc taataccgct ctacccgttg acattcaatg gcgtaaccac aagggagaaa
    35461 ttaagcaaac ccagttatta ttaacatcgg gtaaacagac aattttgcta gagcaatcgg
    35521 tttaaaatca ttctgtaaag gccgtaaggt ttgcgccctt tatcgttagg tatgacgggg
    35581 actgacctcc cgatccttat ttagctccgt ccgccgcctg gcagtcgatg gacgttaagt
    35641 taaaatgctt gtggattcgg tctgacgggg gcataatttt ccgattgtgt ctagttaaga
    35701 ggagtagaag cagcaatctc ccattatagc cgtaggctta acggtgagat tgtcaacacc
    35761 taatcatacc caaaacctca aacctcaaaa attgatattc ctaagccata aacgaaactg
    35821 tcgaggagaa aattacctac acagggccag caaaaaagta atagattggt gtattctcga
    35881 tcaaataggg acgttaataa ttggggcttg ctgaataaat ctaaaaacct tgttgggtaa
    35941 gacttttaga ccttttgtca atcaaaaagt actggatctg ggagtgatcg gggggaaatt
    36001 taggcacttt ttccctgaaa attaggtaat tggccacctc aaaactggta aaaccccaca
    36061 ccccacaccc cacaccccac accctgccac caccgaaaaa ctttttgccg caaaccctaa
    36121 ttgggcataa tgaggggata aaacaatctc ttaatctagg aaagacagat attattttga
    36181 tgaaaggcta tgggtatcag catcctgaga atctgggcga tcgcagctaa cagttttcgc
    36241 gaggttatcc gcgatcgcat tctttacttt atcgggtttt ttgccttgtt gatggccttc
    36301 gcttggcgtt tattaccaga aattgcggtg ggaacccatc agaaaatctt tcttgacttg
    36361 ggattagccg ctatcgggtt attaggggta attgtcgcgg tttttgtggg tacagggcta
    36421 attaataagg aaattgacaa gagaactatt ttagttttga ttcctaaacc cctgagtcgg
    36481 gccgaattta tcctcggtaa acacttgggt ttgtccgggg ttttagcggt gatgttgggg
    36541 gtaatgttgg tgatttacct gctgatgttg tcggggatga aagtatcttt tcaagcttta
    36601 cccctgattg tctcggtttt ctatctcggt ttggaattaa ttctcatcgc ggccgtggcg
    36661 atcgcttttg gggtatttac cagttcgatt ttagccacgt taatgacttt tggggtctat
    36721 ctaatgggtc acatcagcaa agatctgatc caattgggta taatcagcaa aaatcccaat
    36781 atcctcgcta tcactaaaaa tatttatcta attctcccag atttagagag attaaatttt
    36841 agaaacgagg ccgtttatgg tttgctgcct agtgctgatg tcttaatcgg taatgccctc
    36901 tacagtctcg tttatactgg tctattattg ggtatctcca tcctcatctt ttcacgacga
    36961 caattttaac tggggttgcc aaatcatact aaatcctgtt taaaaactat aggatagtgg
    37021 ggtggtcact gcgtgcgcgt tgcgggggga agtggggtga taggggagaa acaatccata
    37081 acttgagagt taatcacact attaaaaacg gatttcgtat caagggatga atgaatgcca
    37141 tcgctggtag gaatggtcaa tatcgattag tttatagaca tgattagcca tgaaattaaa
    37201 ggcacaactg catattttaa gtcgagacgc ggtcaattac ggactggccc ccgtagtcat
    37261 ggaagaagcg gttaatcccg tccttgcggc catggccaga cagttaaaac atttacagta
    37321 ctatgtggtg cagaatggcc agggtgattg gttgctaacc accttagccc atcggcggca
    37381 gccgcaacag gagaaaaggg taatctatgc ctttgctacg gaaaaaatgg ccatatctgc
    37441 tcaaaatacc cccaattcac ccctatcaac gctcctgatt cccgtaaccc atcttttatt
    37501 tcaattattt gccctagaaa aagtagatag tattattttt ctggaaaatg cacacaccgc
    37561 tcaaacggga aaagaaatca cccggaccca attaaaggcc aatattgaaa aacaactgca
    37621 aaaactagcg acaattcctg ccaatcttgc ttaacttagt tatcattaat cgaggtcaat
    37681 tagatgtcac cagagacttt ttcagctgcc aacttgagtc tagtgtaacc agagagattt
    37741 ttgagaaagg aaggtgtcgc tagtgtgggc cacacttcac cccatcagat atagtagaag
    37801 tacagtatat acattctcaa caatacggtg gtcaggatga atacaaaaac ccccaattac
    37861 tagaccgcca gtttcaggat gataaaacgg ctctccagtg tcaagctgta tccctaacaa
    37921 tggagcagtc aaactaggag ccgtgtgagg tgaaagtctc acctacgttt ctcaagggga
    37981 ggagatggag ttgactctat tctcagcccc taatggatag attggactct atcagtatcc
    38041 gccgctacta ataccttaaa tcttagccag aatgccagat ttacacttgc ttaattctca
    38101 tacacaggcc ctagaaaccg ccttcatccc cactgccgac cggtcttttt cctcccctct
    38161 atccctcgac ctggagagaa ttaatcaacg ttttgactcc gctaacgccg cggaaatcgt
    38221 cgcttggtcc gcggccacct ttggggaagg tttggtgatg agtaccagtt tcggcattca
    38281 ggcggcggta atgttgcacc tcgtcaccgc aattatcccc gatattcccg tcatttggat
    38341 cgataccggc tatcttcccc cggaaaccta tcaatttgcc gaagacttaa gccaacgcct
    38401 ccatttaaac ctgaaagttt atcaatctcc cctcagtccc gcccgcatgg aagcaatcca
    38461 cggtaaattg tggtcaaata acgatctcga ctccctcaat ctctacgaca aaatccgcaa
    38521 ggtggagccg atgcaacggg ccctgaagga attaaaggcc accgcttggt tagcaggttt
    38581 acgtcgcgac caaaccgacc accgcaaaac tctccaatgg gtcaatcaac agggcgaacg
    38641 ttacaaaata ttaccgatcc ttgactggaa tgccaaaacc atctacgagt atctgactaa
    38701 atacgatctt ccctaccatc cctattttga tctgggttat gtctccgtgg gcgattggca
    38761 ctccagtcgg cctttaaccg ccaatgatag caacgaacga gacacccgtt tcaagggttt
    38821 aaaacaagaa tgcggtcttc atttgccctt aacccccgga gaagcacaaa gtctcgacgc
    38881 aagctcccta taactgccag ggtgggaaaa ttgccggtgc gatcggttcc tagacgttag
    38941 acaatggtta ttagacctct tgtaaaaatc aaaaattgtt gttaggctta ggagtcagta
    39001 gccagtagtc agtagtcagg agaattaaga agaagtaata atcagttaaa tggtctattt
    39061 acagacttta tgccatttaa tccttatttt tgccgttttt gaaccctgaa aaactaatta
    39121 tgcaagaggt ttattgatta ttaatccccc attaaccatg gctattttag aaaattttct
    39181 cgaagtcggc tctctcaagt ggttttatcg acaggttaac cccgatcaac aaccagacac
    39241 aacccccgtg atcctactcc atggtttacc cgcccatagc tatatttggc gggaattatt
    39301 gaccagttta gaagaatata acattaatgc cattgccccc gattggatcg gttccggttt
    39361 atccgctaaa cccgatgcca gagaattcgc ctacacacct agcgcttttt gtcaagcctt
    39421 ggccgatttt attcaagctc tccaattgcc gaaaatctcc ctcattgtgc agggtttttt
    39481 agcctccgtc ggtttacaat acgccctaga aaatcccgat aaaattgagc gcttgatcgt
    39541 cttaaatact cccctttcca gggatgtcaa attaccctgg ataatgaaac aatgggggct
    39601 acctttcctc ggagatatgg caactcaaga tcccttatta gtcgatcgta ctttagaaac
    39661 cggtagcggt tttgtgatta gcgatgcaaa tctggctatt ttccgtcaac cttatctaaa
    39721 aacttcggca gtgggtcgcg ctttactggc cacgattcgc aatttaaacc tatcgaaaac
    39781 tatggcagaa attgagacag gtttagagca ctttgaaaaa cctatccttt ttgtctgggg
    39841 aatggccgat ccttggttat cttctgtcac tgtcgaaaaa ttggccacta aatcaggagt
    39901 ggaattaatc cccctcacgg aagcaaaaca ctatccccaa gaacattggt caaaagaaat
    39961 taatccccgg attattaatt ttctcggacg caaaacctaa acagctattt aaggtgatgc
    40021 agaaattgtc ccaattaccc ttctctgatt atagtagaag cggaggcttc gctttttcaa
    40081 aatttctgcg tttagggcta gtaatttatc gatataacaa aaaattattg aagtttaaat
    40141 agtgataaaa atttttgttc gttcaaaacg ataggtaagg aggagatata ggaataattc
    40201 tctacaaaga caatttttgg agatttattt atgcaattta gagaatttga ctgggatcag
    40261 tctaaaagat attctaatat agagaagcat gggatagatt ttgcggctgt tcctcctatc
    40321 ttcgatggtc actgtctaat cagagaagat aatcgccaag attaccaaga aataaggatg
    40381 tgtttgctgg gacaattaaa cgagataatc tgttatgttg tctatactat aagaggggaa
    40441 acttgctgat tgattagtaa taggagagca aacgaacgtg agcgaagaaa gtatcaagag
    40501 agtatccccc aagatgggct gagtgcctga cacatcttgt gtaaggggta gcaggtcaag
    40561 gacgacagag caaagagtga acacgggaaa accatattcg gtcatagtaa tcggagagag
    40621 cgttcttaga agagaaacag ggttctgggt cagagtggaa caaagggata ggagaaagca
    40681 aagagcggcc cttgtggaca acgccctgga gccaacgaag accaattttg agatagctga
    40741 gaccccgcgt ccaatggggg tcaacctgag agcgaagacc attgagttga acggccatac
    40801 cgtgagtagt ggcataaaga agagcaaggg ctgcgaccaa atacagacgg gtcaaagcag
    40861 gagcagaacg gatagcggag tcttcaagtt gaaaagcacc ggattttgaa tctaaaaata
    40921 actcctcgac ccgaaagcgc aaggcgtact gccctaaagt gttcagagag ggggtttcgt
    40981 cagtaatgac agcccaaggt tctttgactc ccgtgaccct tgccagaaca agattgcatc
    41041 gatagatgcc gtctgtccac agaccgacct gatcgtaaag aatggcttct cctttggcag
    41101 gccagagata tttgacttcg ataggatgtc gccgaacccc atggaccaga acgtcgccag
    41161 gtaaacgtaa gcagtagacc tcctgcaaaa gtcttattca gctacttgat gatagcctaa
    41221 agcaagttca tagttgtaaa tgccagcgat taaattaaat ctcagaccaa aacgccgtct
    41281 ccgattccta tatcttgatg ataaaattct aaatatcttc agacttctgt gaatatgttc
    41341 gataataatt ctttctcttg ataactggcg attaaattct ttctcttctg aacttaattc
    41401 ttgatttttc ttctttttgt aaggaatcct actattttca tgctgttttt ggattccttg
    41461 atcgccctta tctgctaaac attcaatact tttatctatc ccaatttgac tatttttcca
    41521 aaggttaaag tcatgtattc ttccctttcc atgagcggta cagattatca ttcctgtttt
    41581 ttgagccgca agaacttgag attttattgt atgatagccc tgtttcccgc tatagtaatc
    41641 tttctgcttc ttttgaggtc tttctatctc atgctctgct acatctacta ccactacctc
    41701 taggtcacta ttggcttgtt gaactgtctt tttacctggc agattaaata atcctgattt
    41761 catgagaata ccttctaccc ttctagtgat tcgtagggct gttgtctcat taatctccca
    41821 gttaattgcg agatggaaat aagtcctata ttcccgcaaa tactctaagg tcatcaagat
    41881 ttggtcttct aaacttaatt tacttggtct tcccgatttt ttttgcagaa ctttttcggc
    41941 ggccagaact ttcaccatat ccttaaatgt ttcaggatat accccacaaa agcgtttaaa
    42001 ctcttctgga ttcaaatttt ttactttttc gtaagtcatt gtttttctga gtgttttact
    42061 ttatggttct tcggtttgtc ttatgcaatg gacgggggtt ataaggtatg taacccttat
    42121 atagaaaggc atttagcgat ttttgttaat ttttttttga tctagagcga actaatcaat
    42181 taaatctctt gccagataag gatttagtcg atttatgccc cccgatcgaa ccataccaag
    42241 taacgaagaa cctactttat tttacataat cagttcctat ttttgcagga ggtctagtaa
    42301 tgccatccac tgacttgccg ccaactgagc aagccatgat tggcaaaccc tcggtcggct
    42361 aagagcatga catcgggata atccttcaac aatcgctgag ccaagcgcag catcggtttg
    42421 tcggtgttca ctgcgacggt ggcactcgga tggtctagca ctcgccataa cagggggact
    42481 gcacgaccgc aacagactat cgacagatga atcatacaat agcgattcca caatacagtt
    42541 gtatctaatg ccaagtaaag tcgattgcct ttccagctac tgatggcggc tagcaccaga
    42601 ggaatataca gggatttgac ccgaattcga tcccacattc cgcaccctaa agtgtcacat
    42661 tgaaaatttt atctaaatcg tcaaaacgat tgccggctct gaattacagg ctaatttgtt
    42721 tgcccagcag atgcacaatt agccctaaaa atctgatagc tctgatacca aattattgag
    42781 ataaactctc attaagctgg cgatcgctga ctagagtgtg acacttcata attcttagta
    42841 atcgctaaaa gtcttactat acaagggcta gagcaacttt tgatttcaac gaccagggtg
    42901 cggaatgtgg gttcgatgat tgcccataaa tctctgccat ctgcgttcgg tgctttgtgc
    42961 ctgtgttgca cgactaggga cgtaggactc ccacattggc aggcttaatt tcccgctaca
    43021 gattactgct gtgaccatcc aggctaatgc cttgaggtgt cgcaggtctc gccattggct
    43081 gtgttgacac agtaaagaaa gtagttgagc atagagactg gtagtggttg acatgggagg
    43141 ttcgctgatg ttctgttaat ctcagcattc catatcctgc tacctttttc tctttccacg
    43201 ctatttcaag ggtttccgac acttgtgtca ggcactcagc aagatgggga ttgttaacac
    43261 aaaagaggaa aggcaagatt taaccgattg ggagcgagtt aaatcgatga gcgatgcaga
    43321 aatcgaggct aatgctctgt cggctcccga tgcgcttcct tttgatgata attgggaaaa
    43381 tgcggagatc atttctccca aaatatggga ataatataat cggctagtca aatatagcaa
    43441 ttcccatagt tgtgaggtac agagtagacc tcttgcatat agcaattccc atagttgtga
    43501 ggtacagaat cttaggtttt gaggagtcag gagttaagat tttggtgtac ctcatgagat
    43561 tgggaaacgc tataattttt ttatggtata atataaggct ttgctttttt ctcgattttt
    43621 agattgaagt ggaaaaaaga ataaaatgtg atcttaggtc aggaaatcat ctataatttt
    43681 gctatgttta ttagcaaaat tatggattat caaaacttat cagatgaaca attcaaacgc
    43741 cgtttcggtg tgtataaaca aacatataga aagatggtag aatcagtaaa aagtgttgaa
    43801 gccgactcta attcaccatc taaaagggga ccgaaaccta aactatctat agaagaacaa
    43861 gttttagtaa cgttagaata ttggcgagaa tatagaacat attttcacat tggtacaagc
    43921 tgggaactat cagaatcaac tataggtcgg attgtaaata agacggaaaa aatgctttga
    43981 caatcgggaa acttccgttt aaaaggaaaa aaagctttac tcaatcaagc agagataccg
    44041 gtcgtaacgg taatggatgt aacggaaact cccattgaac gcccccaaaa gaaacagaaa
    44101 gatttttttg ggggtaaaag aggttatcat actttaaaat cccaattagt agctgatcaa
    44161 aatacagagg aaattatctg tgtcttttgt gggaaaggca gaggtcatga ttttagttta
    44221 tttaaaaaaa gtcgagttcg ttttcatcct ttaactacca gcatagaaga cagtggttat
    44281 cagggaatag ctgcatacca tagtaatagt tatacaccga aaaagaaacc gaaaaatgga
    44341 aaattaacag acttagaaaa ggagtataac aaggctttgg ccaaagaaag aattatcatt
    44401 gaacctataa atagggtttg ctgaaaaagc ttttcggtgg tggcagggtg tggccccccc
    44461 aacccccccg acatcggggg ggcaggtggg gtgtggggtt ttaccgattt tgaggtagtc
    44521 agttgcctaa ttttcaggga aaaagtacct gaattttgcc cccgatcccc gcaatggctg
    44581 gcactttttg agggaaaaaa agtctaaaag tcttatccaa caaggttttt agatttattc
    44641 agcaagccct aaataggaaa ctcaaaatct tgaaaatctt atcctgtaaa tatcggaatc
    44701 gtcgtcgaag atatagttta agagttaact tgttggcggc tatttataac tgtgagttag
    44761 ggataggtat agcagcttct taaaagttgc ctaaagatta atcaagtcaa ggagaattta
    44821 ttctcaatta taaaaattga gatagtttgt gccgcttaaa taaagaggtt ttgataacca
    44881 aattaaagca tatctaaaga gttttgagtt aaaagttaaa cttcaagttt ttatttagta
    44941 caaatgtact ggttaactaa ttttttgggg aaaattagtt aacccatcat tataacatat
    45001 aattaatttg caagagttct actatttaac ttggttggtg gacttccccc ttgcggacga
    45061 ggacggatat ctcctgtttc tttatgttgc ttcaataact tctgaataaa gcttttagcc
    45121 acgtcaaatc tctgggctag tcctcgaatg gaaatttttt ctttcttcca gacatcgata
    45181 attttttggc gaaaatctac ggaatagggt ctcataggaa gctggtaagt tctattattt
    45241 gtctatttgc tttccattgt acctcatagc tccaagaatt gctatatatt acagcaactc
    45301 aagtctgtga acttcttaaa aaaatagctg ctttaggact aactattccc atcactctag
    45361 tattagataa tgcccgctat caaaaatgta aaattgtcga agaattggct ctttctttgt
    45421 caatagaatt actctatctg ccgtcttatt cgcctaatct caatttaatt gaaaggctgt
    45481 ggaaatttgt caaaaaaaat gtttatagca attcccatag ttgtgaggta cagagtctta
    45541 ggttttgagg gttcgggatt caggagtcag gagtcaggat tcgggattca ggagttaaga
    45601 ttttggtgta cctcatgaga ttgggaaacg ctatatatag taaatattat gagaactttt
    45661 ctgacttttc ttcagctatt tattaatgtc tgaatgatgc ccatctgaaa cataaaaaag
    45721 aactggattc cttgctgact ctacgatttc agaagtttaa taaatctcag attatgaacg
    45781 tctaaagtat atctcgattg taacgcccct ttgagagcca gtttcaaatt gtcgataata
    45841 tcatcgggta attttgagag gttggccagg gttctttttt taacttgatc tccttctcgg
    45901 taagaatcag gtcgaagaac ggcgggaggg gaattacggt
//
