LOCUS       NZ_AP024135            24590 bp    DNA     linear   CON 08-NOV-2024
DEFINITION  Streptomyces sp. EAS-AB2608 strain NBRC 114648 chromosome.
ACCESSION   NZ_AP024135
VERSION     NZ_AP024135.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. EAS-AB2608
  ORGANISM  Streptomyces sp. EAS-AB2608
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Kitasatosporales; Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Okubo,S., Ena,E., Okuda,A., Kozone,I., Hashimoto,J., Nishitsuji,Y.,
            Fujie,M., Satoh,N., Ikeda,H. and Shin-Ya,K.
  TITLE     Identification of functional cytochrome P450 and ferredoxin from
            Streptomyces sp. EAS-AB2608 by transcriptional analysis and their
            heterologous expression
  JOURNAL   Appl Microbiol Biotechnol 105 (10), 4177-4187 (2021)
   PUBMED   33944982
  REMARK    DOI:10.1007/s00253-021-11304-z
REFERENCE   2  (bases 1 to 9320785)
  AUTHORS   Okubo,S., Ena,E., Okuda,A., Kozone,I., Hashimoto,J., Nishitsuji,Y.,
            Fujie,M., Satoh,N., Ikeda,H. and Shinya,K.
  TITLE     Direct Submission
  JOURNAL   Submitted (28-OCT-2020) Contact:Shinya Okubo Eisai Co., Ltd.;
            Tokodai 5-1-3, Tsukuba 300-2635, Japan
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Newbler v. 2.9
            Genome Coverage                   :: 53x
            Sequencing Technology             :: Miseq; PacBio RS II
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_019703895.1-RS_2024_11_06
            Annotation Date                   :: 11/06/2024 09:16:33
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,174
            CDSs (total)                      :: 8,084
            Genes (coding)                    :: 7,890
            CDSs (with protein)               :: 7,890
            Genes (RNA)                       :: 90
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 194
            CDSs (without protein)            :: 194
            Pseudo Genes (ambiguous residues) :: 0 of 194
            Pseudo Genes (frameshifted)       :: 87 of 194
            Pseudo Genes (incomplete)         :: 132 of 194
            Pseudo Genes (internal stop)      :: 10 of 194
            Pseudo Genes (multiple problems)  :: 32 of 194
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 13:41:52
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 8836433
            Orig. end                         :: 8861023
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            AP024135.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..24590
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="38"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..24590
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..24590
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:14590]"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..14590
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            371..>2107
                     /locus_tag="K6K39_RS38710"
                     /old_locus_tag="EASAB2608_07930"
                     /pseudo=""
     CDS             371..>2107
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0003723 - RNA binding [Evidence IEA]"
                     /GO_function="GO:0003746 - translation elongation factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0005525 - GTP binding [Evidence IEA]"
                     /GO_process="GO:0001514 - selenocysteine incorporation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1190: GTP-binding protein LepA"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012239.5"
                     /locus_tag="K6K39_RS38710"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="EASAB2608_07930"
                     /product="SelB C-terminal domain-containing protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MRVLATAGHVDHGKSALVRALTGMEPDRYEEERRRGLTLDLGFVW
                     TRLGGDHLAFVDVPGHERFVPTMLAGAGPVPAVLFVVAADQGWQPQSAEHLAVLDALGV
                     RHAVLAVTRSDLADPEPVRADAVERLAGTSLGTVPQVAVSAVTGAGLDELRTALSRLAA
                     TLPAPDPDADVRLWLDRAFTVRGHGTVVTGTLGAGTLRVGDRLVTADGSAVLRVRGLQS
                     LHEERTAVGAVARVAVNVHGPGAGGLCRGQALLTPGRWLCTEAADVRIAGEPTAGVPRC
                     AVLHIGTAAVPVTVRPLGRDTARLTLRRALPLRAGDRAVLREPGGTRLPRGVTVLDVRP
                     PRLTRRGAGRARAAELDTMTGRPDGAAELRRRKLIRRADLRAMGVPVPGEPVAGDWLAD
                     PAHWSALRDRLAGQVLAHAQAHPLDPGLPAEAARRLLALPDRALVDALAAALPRIHARQ
                     GRLYPADSLRPALPAPVRAAVDALRRDLARTPFRAPEAGRLTELGLDRRTVAAAAAAGA
                     LLRIADGIVLLPGADADAAAVLRALPQPFTLSEARRALDTTRRVAVPLLEFLDARGHTE
                     RVD"
     tRNA            complement(2143..2235)
                     /anticodon=(pos:complement(8838631..8838633),aa:Sec,
                     seq:tca)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="K6K39_RS38715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /product="tRNA-Sec"
     gene            complement(2143..2235)
                     /locus_tag="K6K39_RS38715"
     gene            2273..3289
                     /gene="selD"
                     /locus_tag="K6K39_RS38720"
                     /old_locus_tag="EASAB2608_07931"
     CDS             2273..3289
                     /EC_number="2.7.9.3"
                     /GO_function="GO:0004756 - selenide, water dikinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0001887 - selenium compound metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="selD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019980784.1"
                     /locus_tag="K6K39_RS38720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EASAB2608_07931"
                     /product="selenide, water dikinase SelD"
                     /protein_id="WP_059247274.1"
                     /transl_table=11
                     /translation="MTATPATRQAPVRLTQFARGGGCACKIPPGELEEVVAGLTAPPLP
                     GGDTPLLVGLATGDDAAVVTHRGTAVVGTADFFTPVVDDPYDWGRIAAANALSDVYAMG
                     GRPVLAVNLLAWPRDRLPFDLAREVLRGGLDIATEAGCHVGGGHSVDDPEPKYGMAVTG
                     LADPQRLLRNDAGRPGLPLSLTKPLGTGVLNNRHKATGERFEHAVATMTALNREASEAA
                     LAAGARCATDVTGFGLLGHLHKLARASGVTAVVDTAAVPCLEGARQAVRDGYVGGGTRR
                     NLAWVAPHTDFGATDADTRLLLADAQTSGGLLVAGEVPGAPVVGELVPRGPHSLVLR"
     gene            complement(3293..6562)
                     /gene="fdh"
                     /locus_tag="K6K39_RS38725"
                     /old_locus_tag="EASAB2608_07932"
     CDS             complement(3293..6562)
                     /EC_number="1.17.-.-"
                     /codon_start=1
                     /gene="fdh"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1134: flavodoxin"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019062188.1"
                     /locus_tag="K6K39_RS38725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EASAB2608_07932"
                     /product="formate dehydrogenase"
                     /protein_id="WP_221335450.1"
                     /transl_except=(pos:complement(8842429..8842431),aa:Sec)
                     /transl_table=11
                     /translation="MGVRTWIGSWPVLRQLTGTDPLGRGAAAKSGRSARLTPRVATADR
                     VVKSVCPYCAVGCGQNVYVEGGAVTQIEGDPDSPVSRGRLCPKGAASLQLTTGDAREHH
                     VLYRRPHGTAWERLDLDTAMDMIADRVIEARRAGWQWEVDETRTRRTLGIASLGGATLD
                     NEENYLLKKLFTALGAIQIENQARVUHSSTVPGLGTSFGRGGATTFQQDLQNADCIVIQ
                     GSNMAECHPVGFQWVLEAKARGAKVIHVDPRFTRTSALADLHVPLRAGTDIAFLGGIVN
                     HVLQHGKYFREYVVAYSNAPVILREDFRDTEDLAGVFSGLDTGTRSYDNASWQYAGTEQ
                     QAASGERDQEYEERTGGGRSVAEAARGEAHGAGGAAIGEGEPERDETLTHPRCVFQVLK
                     RHYARYTPDLVERVCGVPRDLFRQVCELVTENSGRDRTTAFAYAVGWTQHTVGVQNIRA
                     ASVLQTLLGNIGRPGGGILALRGHASIQGSTDIPTLFNLLPGYIPMPHAHQNQDLAAFV
                     AAEAARKGYWGNMRAYLVSLLKAYWGDAATPENDFCFDYLPRLTGSHSTYETTMAQLDG
                     VCKGYFLLGENPAVGNADAKLMRLGMANLDWLVVRDFSLIESATWWRDGPETETGELRT
                     EDIRTEVFFLPAAAHTEKDGSFTNTQRLLQWHHQAVEPPGEARSELWFAYHLGRIVREK
                     LAGSTDEMDRPVLDLAWDYPTRGRHAEPDAEAVLAEINGRDAEGNPLSSYEQLKPDGST
                     ACGCWIYCGVYADGVNQAARRRPGREQDWVAAEWAWAWPANRRILYNRASADPEGRPWS
                     ERKALVWWDPDKGARGEWTGHDVPDIEKDKAPDHEPPEGATGPQALSGTDPFLMQADGK
                     AWLYVPSGLTDGPLPAHYEPQDSPFPNLLYDQQRNPVRQLLPPHPDNRYQPSGDEPGAR
                     VFPYVATTYRLTEHHTAGGMSRWQPYLAELQPEFFCEVSPQLAAERGLTHTGWATIVSA
                     RGVVEARVLVTDRMVPLTVHGRPLHQVGLPYHWGPNGRSTGDAANELLHLSLDPNTHIQ
                     ETKAFAVDIRPGRRPRGEAALALVRAYRIRAGIDERTGTGP"
     gene            complement(6635..7420)
                     /locus_tag="K6K39_RS38730"
                     /old_locus_tag="EASAB2608_07934"
     CDS             complement(6635..7420)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014055983.1"
                     /locus_tag="K6K39_RS38730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EASAB2608_07934"
                     /product="HD domain-containing protein"
                     /protein_id="WP_086702903.1"
                     /transl_table=11
                     /translation="MTHEGKDGQRPSRRTVLQRGAGVAAAGAATALTGPPAAAHPLPSP
                     RSDALPEAVAGVRIPGSGPARQAVRLARRVSSETLFHHVMRTYVFGALLFDRRGVRYDR
                     ELAFVAAVLHDLGLVEEFRTPAERFEVDGADAARRFLERLGMPAERVEVVWDAIALHTS
                     VGIATRKRPEIALVSVGSGLDFTGDGLERIPSDALDAVLTAFPRRGFKQEALDTVLSLC
                     RTKPMAELMHPFAEVGRRHLPGFPVPTLEDLLLAAPFDE"
     gene            complement(7699..9288)
                     /locus_tag="K6K39_RS38735"
                     /old_locus_tag="EASAB2608_07935"
     CDS             complement(7699..9288)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012998484.1"
                     /locus_tag="K6K39_RS38735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EASAB2608_07935"
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="WP_221335451.1"
                     /sec_met_domain="DAO (E-value: 4e-15, bitscore: 55.1,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNRAGHPEHTRHGRDRRARLLPARPGKPRVDGPRPTTAVVGGGIA
                     GLAAATALAERGVAVTLYERQPYLGGRAGGWPTRLRDGTPVTMSRGFHAFFRQYYNLRA
                     LLRRTDPGLRRLTALPDYPLLHADGMRDGFRRVPRTPPWSALGFAALSPSFTVRDLRRM
                     GPVAALPLLDVRVPEIYDRLDHISAHDFLDAVRFPARARHLAFEVFSRSFFADPRELSA
                     AELALMFHIYFLGSAEGLLFDVPRAPFPSALWHPLADHLRRHGAELRTSTAVDHIAPVP
                     GGGYRVATDRDERSHDTVVLALDTAGLRHVVGRSDRLGDAPWRERIARLRNAPPFLVTR
                     LWLDRPVAPGRPGFLGTGGFPTLDNVSVLERWEDEAAHWAARTGGSVLELHAYAVGART
                     PRDVEEKHLIEQLHRVYPETRGAAVLDVRHEWRADCPLFPVGGYRGRPAVHTPDPGLVV
                     AGDLVRTGLPVALMERAATTGFLAADALLERWGVRGVPLWTVPDRGRSALLRGLAGWAG
                     PPGRRAGRRQRG"
     gene            complement(9285..10004)
                     /locus_tag="K6K39_RS38740"
                     /old_locus_tag="EASAB2608_07936"
     CDS             complement(9285..10004)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014677064.1"
                     /locus_tag="K6K39_RS38740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EASAB2608_07936"
                     /product="methyltransferase"
                     /protein_id="WP_059247270.1"
                     /transl_table=11
                     /translation="MTLLRDEDLTAAFDHASRSYDALTAANPGYRAHLRRSVRRLGLPG
                     DGAGLRLLDLGCGTGASTAALRAALPAARITAVDASAGMLRRAAAKPWAGAVTFVRAPA
                     ERLAEAGVTGPFDAVFAAYLLRNVSDPDAVLAGVRDLLAPGGRLGVHEYALSGRRADRA
                     VWTAVCRGLVQPVASVLGDGRLYRHLWRSVLEFDTADRFAARVRAAGFTHVRALPLPGW
                     QTGIAHTFVARRPEAAR"
     gene            complement(10001..11224)
                     /locus_tag="K6K39_RS38745"
                     /old_locus_tag="EASAB2608_07937"
     CDS             complement(10001..11224)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: Lycopene_cycl"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014670291.1"
                     /locus_tag="K6K39_RS38745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EASAB2608_07937"
                     /product="lycopene cyclase family protein"
                     /protein_id="WP_059247269.1"
                     /sec_met_domain="Lycopene_cycl (E-value: 3e-99, bitscore:
                     331.5, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLEAEVAVVGAGAAGLSLAHRLAGPGRGPRTPSVVLVDAPPGPLR
                     PPRRTWCFWEAGPGRFDAALTASWRHLRVRPPTGDPIEADLAPLRYKMLRSDDFEDLVR
                     RDLARSPNVRRVEATVETVEEFEGGAHVRLRHPDGGTGVLRARWVFDSRPLGSLPAART
                     TLLQHFHGWFVRTARPAFDPGTVDLMDFRTAQPATGLSFGYVLPTGPREALVEYTEFSP
                     RLLTGSGYEAAVRAYAHDVLRLGDSQVLATETGVIPMTDAPMPRRVGARVFRIGAAGGA
                     TRPATGYTFAGLQRQTRAVAAALRRGQRPVPPPAHSARSRAMDAVLLRALAGGRVDGPA
                     LFCDLFRRVPAPRLLRFLDGRTRLREDLAVGLRTPIGPMLRSALELPGLPRRPFDRPAP
                     EPPPLETV"
     gene            11506..12048
                     /locus_tag="K6K39_RS38750"
                     /old_locus_tag="EASAB2608_07938"
     CDS             11506..12048
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="K6K39_RS38750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="EASAB2608_07938"
                     /product="hypothetical protein"
                     /protein_id="WP_059247268.1"
                     /transl_table=11
                     /translation="MCPTQAKEHHPAAAPPAPRPVPQPGSPVRTRPYGGTGAARCTPGR
                     TPGAARCAAPPGATAARAADADVPAGRVHGHVPGDRGSRARALDAPFAGEAAGRAARFP
                     RAAGTHPPSRHPWRTPPARGGTGETAVSRTGALLGLSSVSRTGAPPGLSPAPALAHRGL
                     RAAAPSPVTRGAKESGR"
     gene            12045..13583
                     /gene="crtI"
                     /locus_tag="K6K39_RS38755"
                     /old_locus_tag="EASAB2608_07939"
     CDS             12045..13583
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016166 - phytoene dehydrogenase activity
                     [Evidence IEA]"
                     /GO_process="GO:0016117 - carotenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="crtI"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007496678.1"
                     /locus_tag="K6K39_RS38755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EASAB2608_07939"
                     /product="phytoene desaturase family protein"
                     /protein_id="WP_059247267.1"
                     /sec_met_domain="DAO (E-value: 3.2e-16, bitscore: 58.7,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRRTLPGRTDHVVVVGAGLAGLSATLHLLGAGRRVTVVERDPVPG
                     GRAGRLDLGGYRIDTGPTVLTMPDLAEEAFAAVGDSLHRRVELVPLHPAYRARFADGST
                     LDVHTDADAMTAEVERFAGSGEAAGYRRLRDWLERLHRAQMRRFIDANFDSPLNLLNSD
                     LARLAALGGFGRLDARIGRFLRDERLRRVFSFQALYAGVPPARALAAYAVIAYMDTVAG
                     VYFPRGGMHALPRAMADAAADAGADLRYGQRVTRLERSGDRVTAVVTDQDRIPCDAVVL
                     TPDLPVAYRLLGRRPRRPLRLRHAPSAVVLHAGTDRTWPHLAHHTLSFGAAWRTTFDEL
                     TRTGRLMSDPSLLITRPTTTDPGLAPPGRHLHYILAPCPNTDIGPDAAAWGDLGPRYRD
                     TLLRELQRRGLDGIEAAVQEECLVTPATWQAAGHAAGTPFSAAHTLAQTGPFRPRNLVR
                     GTENAVLAGCGTTPGVGVPTVLVSGKLAAARITGPPPAPPLPRAAAAYGEAAGV"
     gene            13580..14590
                     /locus_tag="K6K39_RS38760"
                     /old_locus_tag="EASAB2608_07940"
     CDS             13580..14590
                     /EC_number="2.5.1.-"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016827627.1"
                     /locus_tag="K6K39_RS38760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EASAB2608_07940"
                     /product="phytoene/squalene synthase family protein"
                     /protein_id="WP_221335452.1"
                     /sec_met_domain="phytoene_synt (E-value: 2.9e-113,
                     bitscore: 376.5, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 2.1e-59,
                     bitscore: 200.1, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDRELDAAGIGDPALRAAYRHCRALNARHGKTYFLATRLLPVER
                     RPAVHALYGFARWADDIVDCLGPGADTGRRAAALTGLRRSLEEGLRDGHSHEPVVLALA
                     DTARRYGIEPALFHDFMSAMSADLTVTDYADYAALRGYMHGSAAVIGLQMLPVLGTVVP
                     REEAAPYAAELGVAFQLSNFLRDVGEDLDRGRVYLPADLLAGHGVDRELLRWSRDTGRH
                     EPRITSALREFEALTRGVYRQALPGLAMLAPVSRPCIRTAFLLYRGILNAVARDGYSVL
                     HRRAVVPRRRRAAVAADGLARAVAARLRAGRSPAPCPPHAPAPGTPCPPAAKEVM"
     gene            14587..15681
                     /locus_tag="K6K39_RS38765"
                     /old_locus_tag="EASAB2608_07941"
     CDS             14587..15681
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003987730.1"
                     /locus_tag="K6K39_RS38765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EASAB2608_07941"
                     /product="DUF5914 domain-containing protein"
                     /protein_id="WP_221335453.1"
                     /transl_table=11
                     /translation="MKPVPSGRRGRLPLSLRRRPVPWERQRPTWRDAGPAVIARALKRA
                     EARPSGNWYVVGASGELRADRPLARTVAGQEVVVWRGPDGRPAGGPGVCPHLGAPLRDS
                     PVRCGTLVCHWHGLALGGTPHAGWVPLPVHDDGVLLWVRLDELGGEAPLDAPVVARRPE
                     RATALTAVYSGTGVCEVEDIVANRLDPWHGAWFHPHAFADLTVVGSPDGADGPPGTVAG
                     SSGIAVGSSGTVAGASGIRGTEDAFTVDVSFKVAGRLVVPVRAVFTAPEPRTVVMRITE
                     GEGAGSVVETHATPLGPDELGRPRTAVTEAVLAVSDRPGFAVVRRAAPLLRPLVRAAAG
                     RLWRDDLAYAERRWHLRSTGRFPG"
     gene            complement(15773..16786)
                     /gene="nrfD"
                     /locus_tag="K6K39_RS38770"
                     /old_locus_tag="EASAB2608_07942"
     CDS             complement(15773..16786)
                     /codon_start=1
                     /gene="nrfD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016823435.1"
                     /locus_tag="K6K39_RS38770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EASAB2608_07942"
                     /product="NrfD/PsrC family molybdoenzyme membrane anchor
                     subunit"
                     /protein_id="WP_221335454.1"
                     /transl_table=11
                     /translation="MSGSDVTRDGVRGARPGREAVPGAHVGRRRRGHGRGERPVVPDAE
                     FASYYGTPVLTKPPWKPLDIAGYLYLGGLAGASSLLAAGGQLTGRPGLAAPAKLGAAGA
                     VSLSLAALVHDLGRPARFLNMLRVIKPTSPMSVGSWLLAGYAPLTLTAAATEVAGRYRL
                     LGSAATVAAAVLGPAVATYTAVLLSDTAVPAWHEGYRELPFVFAGSAATAAAGLALAAV
                     PVVQAGPARRLAVLGAALELGAFRAMRRRMGLAAEPFGQGRARVLVRAAELLTAGGAVL
                     ALCRGRDRRLAMAAGTALLTGSAALRFGVFHAGVASAEDPAYTVVPQRERLAARGG"
     gene            complement(16875..17816)
                     /locus_tag="K6K39_RS38775"
                     /old_locus_tag="EASAB2608_07943"
     CDS             complement(16875..17816)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014670625.1"
                     /locus_tag="K6K39_RS38775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EASAB2608_07943"
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="WP_059254734.1"
                     /transl_table=11
                     /translation="MGDGAEDRGNALYGPQPDVAGASGYPDAPPRVGFFTDTSVCIGCK
                     ACEVACKEWNAIPAGGLALTGMSYDNTRGLGADAWRHVAFVEQRGPFGGPEPSAAQDDA
                     GDVDVFTAAARISPASPDGGTGLRWLMASDVCKHCTHAACLDVCPTGSLFRTEFGTVVV
                     QEDICNGCGYCVPACPYGVIDRREDDGRVWKCTLCYDRLGVGLEPACATSCPTDSIQFG
                     PLEELRERARARVAQLHAAGATDARLYGESPDDGVGGAGAFFLLLDEPEVYGLPPDPVV
                     TTRDLPAMWRQAALAAVSLTALAAGSFARRRR"
     gene            complement(18044..18493)
                     /locus_tag="K6K39_RS38780"
     CDS             complement(18044..18493)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006374425.1"
                     /locus_tag="K6K39_RS38780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ATP-binding protein"
                     /protein_id="WP_059247264.1"
                     /transl_table=11
                     /translation="MDIPLRTHATTQDRPAPLRYSRTWGTGVSSIAEARDAVAALLARV
                     RPALGRRPVQDAQIVVSELVTNAAQHAPGPCALRLELLPGASALRVTVTDTSPEPPRRH
                     PPDPRRVGGHGLHLVAMLSRGLEVTWLSRGKRVSATVPLGPAAAD"
     gene            19435..20157
                     /locus_tag="K6K39_RS38785"
                     /old_locus_tag="EASAB2608_07946"
     CDS             19435..20157
                     /EC_number="3.1.-.-"
                     /GO_component="GO:0005829 - cytosol [Evidence IEA]"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019056184.1"
                     /locus_tag="K6K39_RS38785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EASAB2608_07946"
                     /product="dienelactone hydrolase family protein"
                     /protein_id="WP_059247263.1"
                     /transl_table=11
                     /translation="MTVTTRTIEYTADGLTMIGHLALPAGDDRRPAVLVGPEGMGLSDV
                     ERRRADALAELGYVALAFDLHGGRYLGDPEEMLARCLPLLADPDRMRGIGHAALGVLRA
                     EPRTDPDRIAAVGYGTGGAIALELGRDGVDLRAIGTVNGLTTGRPGETARIHCPVWAGV
                     GSEDPIMPPAQRNAFTAEMQAAGVDWRLTVYGGALHAFHHPTVDHPTVPGVGYHPQHAR
                     RAWRDVVDLLAECLPITE"
     gene            complement(20435..20728)
                     /locus_tag="K6K39_RS38790"
                     /old_locus_tag="EASAB2608_07947"
     CDS             complement(20435..20728)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003987675.1"
                     /locus_tag="K6K39_RS38790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EASAB2608_07947"
                     /product="DUF1330 domain-containing protein"
                     /protein_id="WP_059247262.1"
                     /transl_table=11
                     /translation="MPKGYWVSVYRTISDPEKLAAYNELARLAVEAGGGRVLVRGGRVV
                     AHDAGIAERTVLIEFDSFEQAVAARESAAYQEALIALSDGVERDFRIVEGID"
     misc_feature    complement(20755..20771)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 14.8"
                     /tool="antismash"
     gene            complement(20783..22216)
                     /locus_tag="K6K39_RS38795"
                     /old_locus_tag="EASAB2608_07948"
     CDS             complement(20783..22216)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1005: Drug
                     resistance transporter, EmrB/QacA"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010040870.1"
                     /locus_tag="K6K39_RS38795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EASAB2608_07948"
                     /product="MFS transporter"
                     /protein_id="WP_059247261.1"
                     /transl_table=11
                     /translation="MTGRPVGGVAVEAFPVARSEARLLVPALMFLSLVVAAIASLGTPL
                     ITSVATSFHVSLGSAQWTLTAALLSGAVATPVLGQLGAGPHRRATILATLAVVVAGSAL
                     TVLPLPFAWLLAGRAAQGVGLGLTALMMGVARDHLPEERSAAVIALISVVSVIGAGVGY
                     PLAALLAEVGGVRAAYGLGLVLTAAALLTAWRSLPEAPEGRLAQVDVAGAVVLAAALLL
                     VLFLAGERNLWSRHLAVAAGLAVVAVVLLCVWAVIELRSTTPLVDVRAVRHPAVAGANL
                     AMFVGGIGMYLLLTLITRYAQTPRGAGYGFGLTTFVAGLVLIPFSVLGFVAGKLTPRAR
                     KRIADPLLLAGSAVVVGGGFALFAAARSDLAELFAAMGLLGFGVGGFSAAMPGVILAVT
                     PKSETSSAMSFNYVVRSVGYSLGSAIGGLILAAGTGPGHLFPDDSAYTTAALVGVGAMA
                     ITTLTGLALARRRSSGTTP"
     gene            complement(22213..22575)
                     /locus_tag="K6K39_RS38800"
                     /old_locus_tag="EASAB2608_07949"
     CDS             complement(22213..22575)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1135: MarR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014173936.1"
                     /locus_tag="K6K39_RS38800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EASAB2608_07949"
                     /product="MarR family transcriptional regulator"
                     /protein_id="WP_059247260.1"
                     /transl_table=11
                     /translation="MSLTSAATLATLDRTGPRRITDLAAVEGVTQPAMTALVRVMEESG
                     LVERRGDASDKRVTLVCLTEAGASYVRTRRQAGIHAFERLIGELTDDEVEALVAALPAL
                     RHLAELESQDREEPKQ"
     misc_feature    complement(22679..22692)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 12.33"
                     /tool="antismash"
     misc_feature    22682..22695
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 12.37"
                     /tool="antismash"
     misc_feature    22687..22700
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 12.89"
                     /tool="antismash"
     misc_feature    complement(22688..22701)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 12.69"
                     /tool="antismash"
     misc_feature    22840..22852
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 20.33"
                     /tool="antismash"
     gene            complement(22949..24067)
                     /locus_tag="K6K39_RS38805"
                     /old_locus_tag="EASAB2608_07950"
     CDS             complement(22949..24067)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010982257.1"
                     /locus_tag="K6K39_RS38805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EASAB2608_07950"
                     /product="lipase"
                     /protein_id="WP_260336032.1"
                     /transl_table=11
                     /translation="MRFELPEPTGRQAVGSTELHLVDRDRPDPWVADRERELMVSVWYP
                     ARSVSGYSRQPYLRPGAARFVDEAGSFGLARPGEVDWAATRTDAASMAPADDRSRRPVL
                     LYSPGLGVPRALGTSTAVELASRGYVVVTVDHTHETTPVEFPNGRVELQKEPMTGAETV
                     KKAVETRVRDTRFVLDQLAVLRAGRNPDAEGRRLPRGLGGALDLDRIGMYGHSAGGITA
                     AETMRADRRIDAGINMDGTLQYSSTEFLPVALEGLDRPFMLMGKANQTHLNKPSWQSFW
                     DRSTGWKRDLRLEGGGHFSYTDAQTIVPALDEHLDIPAQNREQFIGTVDPERSTAAQRA
                     YVTAFFDQHLLGRPRHLLDKSSSDYPEVRFVR"
     misc_feature    complement(24475..24493)
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 20.66"
                     /tool="antismash"
ORIGIN
        1 gggggcgcac ccggtgtcac cctgcccagc gcggccctct ccctgcccga gccgtacgcc
       61 gccgcgctgc gcaccggccg caccccggtc gtcgggcgcc tggaggcggg gcgctgcctg
      121 ctggacctga gggcggtgcc ggcggaggac gacgaccggc tcgccgaggc cgtgcgctcg
      181 gcccggaccg gcgccgaggg gccgacggca tgacgaggcg ggcggccggg gacggcgggc
      241 gacacgaggc cggcccgcgg gaagaggcgg gcgagacccg gtggcgaacc cggaagggcg
      301 ggcaccatga cgccgccccc cgaggcaagg cggacgagac ggcgccggcc cccgccgaag
      361 ggcgggcgtg atgcgggtcc tcgccaccgc cggtcacgtc gaccacggca agtccgcgct
      421 ggtccgcgcc ctcaccggca tggagcccga ccgctacgag gaggaacgcc gccggggcct
      481 cacgctggat ctgggtttcg tgtggacccg tctcggcggc gaccacctcg ccttcgtgga
      541 cgtacccggg cacgagcggt tcgtgccgac catgctggcc ggtgccggtc ccgtgcccgc
      601 cgtgctgttc gtcgtcgccg ccgaccaggg ctggcagccc cagtccgcgg agcacctggc
      661 cgtgctcgac gcgctcggcg tccggcacgc cgtcctcgcg gtgacccgca gcgacctcgc
      721 cgacccggaa ccggttcgcg ccgacgccgt cgagcgcctg gccggaacct cgctcggcac
      781 cgtgccgcag gtcgcggtca gcgcggtcac cggcgccggc ctggacgagc tgcgcaccgc
      841 actgtcccgg ctggcggcga cgctgcccgc gcccgacccg gacgccgacg tacgcctctg
      901 gctcgaccgg gcgttcaccg tccgcggcca cggcaccgtg gtgaccggca ccctcggcgc
      961 gggcaccctg cgcgtcggtg accggctggt caccgccgac gggtcggccg tgctgcgggt
     1021 gcggggcctg cagagcctgc acgaggagcg gacggccgtc ggcgcggtgg cccgtgtcgc
     1081 cgtcaacgtg cacggtccgg gcgccggcgg cctgtgcagg gggcaggcgc tgctcacccc
     1141 cggccgctgg ctgtgcaccg aggccgccga cgtacggatc gccggggagc cgacggccgg
     1201 ggtgccccgg tgcgccgtcc tgcacatcgg gacggccgcc gtcccggtga ccgtgcgccc
     1261 cctcggccgg gacaccgccc ggctcacgct ccgccgggcg ctgcccctgc gggccggtga
     1321 ccgggcggtg ctccgggaac ccggcggcac ccgcctgccc cgcggggtca ccgtcctcga
     1381 cgtccgcccg ccccggctga cccggcgcgg cgcaggccgg gcccgcgcgg ccgaactgga
     1441 caccatgacc ggccgcccgg acggcgccgc cgaactgcgc cgccgcaagc tgatccggcg
     1501 cgccgacctg cgggcgatgg gcgtcccggt gcccggcgag cccgtcgccg gggactggct
     1561 ggccgatccg gcgcactgga gcgccctgcg ggaccggctg gccggccagg tgctggccca
     1621 cgcccaagcc catccgctgg accccggact gcccgccgaa gcggcccgcc ggctgctcgc
     1681 cctgcccgac cgcgccctgg tcgacgcact ggccgcggcg ctgccccgga tccacgcccg
     1741 ccaaggccgg ctgtaccccg ccgacagcct ccggcccgcc ctgccggcac ccgtccgcgc
     1801 ggccgtcgac gccctgcgcc gcgacctggc ccggaccccc ttccgggccc ccgaggccgg
     1861 acggctcacc gaactcgggc tcgaccgccg aaccgtggcc gccgcggcgg ccgccggggc
     1921 cctgctgcgc atcgccgacg ggatcgtcct gctgcccggc gcggacgccg acgccgccgc
     1981 cgtcctgcgc gcactgcccc agccgttcac gctcagcgag gcccggcgcg ccctggacac
     2041 cacccgccgg gtggccgtac cgctgctgga gttcctggac gcccgcggac acaccgagcg
     2101 cgtcgacgac cggcgccggc gctgccgtac cgacgcggtg aacggaggcg gacaggaatc
     2161 gaacctgccg gcccgagatc ctcgggcccc tcggttttga agaccgggag ggccaccagg
     2221 cacccacacg cctccaccgc tcgtcaggct actgctccag gagaccaccg gtatgacagc
     2281 gacaccggcg acccgtcagg cgcccgtacg gctcacgcag ttcgcccgcg gcggcggctg
     2341 cgcctgcaag atcccgcccg gcgagctgga ggaggtggtg gcggggctca ccgcgccgcc
     2401 gctccccggc ggcgacaccc cgctgctcgt cggcctcgcc accggcgacg acgcggccgt
     2461 ggtcacacac cggggcaccg ccgtggtggg caccgccgac ttcttcaccc cggtcgtcga
     2521 cgacccttac gactggggcc ggatcgccgc cgccaacgcc ctgtccgacg tgtacgcgat
     2581 gggcggccgg cccgtgctcg ccgtcaacct gctcgcctgg ccccgcgacc ggctcccgtt
     2641 cgaccttgcc cgcgaggtgc tccgcggcgg actggacatc gccaccgagg cgggctgcca
     2701 tgtcggcggc gggcacagcg tcgacgaccc cgagcccaag tacggcatgg ccgtcaccgg
     2761 cctcgccgac ccgcagcggc tgctgcgcaa cgacgccggc cgccccggac tgccgctgtc
     2821 cctcaccaaa ccgctgggca ccggcgtcct gaacaaccgg cacaaggcca ccggcgagcg
     2881 gttcgagcac gccgtcgcca cgatgacggc cctcaaccgg gaggcgtccg aggccgccct
     2941 ggccgccgga gcccgctgcg ccaccgacgt caccggcttc ggcctcctcg gccatctgca
     3001 caagctggcc cgcgcctccg gggtgaccgc cgtggtcgac accgccgcgg tcccctgcct
     3061 ggagggcgcc cgccaggcgg tacgggacgg gtacgtcggc ggcggcaccc ggcgcaatct
     3121 ggcatgggtc gcgccgcaca ccgacttcgg tgccaccgac gcggacaccc ggctgctgct
     3181 cgccgacgcg cagacctccg gcgggctgct cgtcgccggg gaggtgccgg gcgcgccggt
     3241 ggtgggggag ctggtgccgc gcggaccgca ctccctggtc ctccggtagg gctcacggcc
     3301 cggtcccggt ccgctcgtcg atgcccgccc ggatccggta cgcccgcacc agcgccaggg
     3361 ccgcctcgcc ccgcggccgt cgccccggac ggatgtcgac ggcgaacgcc ttcgtctcct
     3421 ggatgtgcgt gttcgggtcc agggacagat gcagcagctc gttggccgcg tccccggtgc
     3481 tgcggccgtt cggaccccag tggtacggca gccccacctg gtgcagcggg cggccgtgca
     3541 cggtcagcgg caccatccgg tcagtgacca gcacccgcgc ctcgacgacc ccccgcgcgc
     3601 tgacgatcgt cgcccacccg gtgtgcgtca ggccccgctc ggcggccagc tgtggggaca
     3661 cctcgcagaa gaactccggt tgcagctccg ccagatacgg ctgccagcgg gacatgccgc
     3721 ccgccgtgtg gtgctcggtg agccggtagg tggtggccac gtacgggaac acccgggcgc
     3781 ccggctcgtc gccgctcggc tggtaccggt tgtccgggtg cggcggcagc aactgccgta
     3841 ccggattgcg ctgctggtcg tagagcaggt tcgggaacgg ggagtcctgc ggctcgtagt
     3901 gcgccggcag cggtccgtcg gtgagcccgg acggcacgta cagccaggcc ttgccgtcgg
     3961 cctgcatgag gaacgggtcc gtgccggaca gggcctgcgg accggtcgcg ccctcgggcg
     4021 gctcgtggtc cggggccttg tccttctcga tgtcggggac gtcgtgtccc gtccactcgc
     4081 cccgcgcacc cttgtccggg tcccaccaca ccagcgcctt gcgctcgctc cacggccggc
     4141 cctcggggtc cgcggaggcg cggttgtaca ggatccgccg gttggccggc caggcccacg
     4201 cccactcggc cgccacccag tcctgctcgc ggcccggtct gcggcgggcc gcctggttga
     4261 cgccgtcggc gtacaccccg cagtagatcc agcagccgca ggccgtcgag ccgtcgggct
     4321 tcagctgctc gtaggaggag agcggattcc cctcggcgtc gcggccgttg atctcggcga
     4381 ggaccgcctc cgcgtccggc tcggcgtgcc ggccccgcgt cgggtagtcc caggccaggt
     4441 cgagcaccgg ccggtccatc tcgtcggtgg acccggccag cttctcgcgg acgatccgcc
     4501 ccaggtggta ggcgaaccac agctcgctgc gggcctcgcc gggcggctcg accgcctggt
     4561 ggtgccactg cagcagccgc tgggtgttgg tgaagctgcc gtccttctcg gtgtgcgcgg
     4621 cggccggcag gaagaacacc tcggtgcgga tgtcctcggt gcgcagctcg ccggtctcgg
     4681 tctcggggcc gtcccgccac caggtcgccg actcgatgag ggagaagtcc cggacgacca
     4741 gccagtccag gttggccatg ccgagccgca tcagcttcgc gtcggcgttg cccacggccg
     4801 ggttctcccc gagcaggaag tagcccttgc agacgccgtc cagctgggcc atcgtcgtct
     4861 cgtacgtcga gtgggaaccg gtcagccgcg gcaggtagtc gaagcagaag tcgttctccg
     4921 gcgtcgccgc gtcaccccag tacgccttga gcaggctcac caggtacgcg cgcatgttgc
     4981 cccagtagcc cttgcgggcc gcctcggccg cgacgaacgc cgccaggtcc tggttctggt
     5041 gggcgtgcgg catcgggatg taccccggca gcaggttgaa cagggtcggg atgtccgtcg
     5101 aaccctggat ggaggcgtgc ccgcgcagcg cgaggatgcc gccgccgggc cggccgatgt
     5161 tgccgagcag ggtctgcagc acggaggccg cccggatgtt ctgcaccccc accgtgtgct
     5221 gcgtccagcc gacggcgtac gcgaaggccg tcgtccggtc gcgcccggag ttctccgtga
     5281 ccagctcgca cacctggcgg aaaaggtccc ggggcacccc gcagacccgc tcgaccaggt
     5341 cgggcgtgta gcgggcgtag tgccgcttca gcacctggaa cacacagcgc gggtgggtca
     5401 gcgtctcgtc ccgttccggc tcgccctcgc cgatcgccgc gccgcccgca ccgtgcgcct
     5461 cgccgcgcgc cgcctcggcc accgaacggc cgccgccggt gcgctcctcg tactcctggt
     5521 cgcgctcgcc ggaggcggcc tgctgctcgg tgcccgcgta ctgccagctg gcgttgtcgt
     5581 agctgcgggt gccggtgtcc agcccggaga agacgccggc caggtcctcg gtgtcccgga
     5641 agtcctcccg caggatcacc ggcgcgttgc tgtaggccac gacgtactcg cggaagtact
     5701 tcccgtgctg gagcacgtgg ttgacgatcc cgccgaggaa ggcgatgtcg gtgcccgcgc
     5761 gcagcggcac gtgcaggtcg gcgagcgcgc tggtgcgggt gaaccggggg tcgacgtgga
     5821 tcaccttcgc gccgcgggcc ttggcctcca gcacccactg gaacccgacc ggatggcact
     5881 cggccatgtt cgagccctgg atgacgatgc agtccgcgtt ctgcaggtcc tgctggaagg
     5941 tggtcgcgcc gccgcggccg aacgaggttc ccagaccggg aaccgtggag gagtgtcaaa
     6001 cgcgcgcctg gttctcgatc tggatcgcgc ccagcgcggt gaacagcttc ttgaggaggt
     6061 agttctcctc gttgtcgagc gtggctccgc ccaggctcgc gatgcccagg gtgcgccggg
     6121 tgcgggtctc gtcgacctcc cactgccagc cggcccggcg ggcctcgatc acccggtcgg
     6181 cgatcatgtc catcgccgtg tccaggtcca gccgctccca cgcggtgccg tgcgggcgcc
     6241 ggtagaggac atggtgctcg cgggcgtccc cggtggtcag ctggaggctc gccgcgccct
     6301 tggggcagag ccggccgcgg gagacggggg agtccgggtc gccctcgatc tgggtgaccg
     6361 cgccgccctc gacgtacacg ttctggccgc agccgaccgc gcagtacggg cagacggact
     6421 tcaccacccg gtcggcggtc gccacccgcg gggtcagccg cgcgctgcgc ccgctcttcg
     6481 ccgcggcgcc ccggccgagc ggatccgtgc ccgtgagctg ccggaggacc ggccaggagc
     6541 cgatccaggt gcgtacgccc acgacgccct cctcccactc gtccctcgat gttcccgtac
     6601 ccgggcgatc acggcatctt cggccgtggc cggctcactc gtcgaagggc gcggcgagca
     6661 gcagatcctc cagcgtgggc accgggaaac cggggaggtg ccggcggccg acctcggcga
     6721 acgggtgcat cagctccgcc atgggcttcg tacggcacag cgacagcacc gtgtcgagcg
     6781 cctcctgctt gaatccccgc cgggggaacg ccgtcagtac ggcgtccagg gcgtcggacg
     6841 gaatccgctc caggccgtcg ccggtgaagt cgagtccgga gccgacggag accagggcga
     6901 tctccggccg cttgcgcgtc gcgatcccca cgctggtgtg cagggcgatc gcgtcccaca
     6961 ccacctccac gcgctcggcc ggcatgccca gccgctccag gaaacggcgc gcggcgtcgg
     7021 cgccgtccac ctcgaaacgc tcggccggcg tccggaactc ctcgaccaga ccgaggtcgt
     7081 gcagaacggc ggccacgaac gccagttccc ggtcgtagcg caccccacgc cggtcgaaca
     7141 gcagcgcgcc gaacacgtac gtccgcatga cgtggtggaa gagcgtctcg gaggacaccc
     7201 tgcgcgccag ccgcacggcc tgccgggccg gcccgctgcc ggggatccgg acgccggcca
     7261 ccgcctcggg cagtgcatcg gagcgcgggc tcggcagggg gtgcgcggcg gcgggcgggc
     7321 cggtgagcgc ggtcgccgcg ccggccgcgg cgacaccggc cccgcgctgg agcaccgtgc
     7381 gccggctggg ccgctgtccg tccttgcctt cgtgggtcat ctggtcgtcc ctctcgctga
     7441 cggcttgtcg ccgagagcct aggaacggcg gccacggacg gaacagcagc ggaaatgaca
     7501 gagggttccg gattctcgcc agccaccgcc aggtggtccg acgtcacccg cttcaccaca
     7561 ggaccccggt gagcgccggg gccgtccagc agcgtgcgca gctctgcgac gccctcctgg
     7621 cgttggtccg ggcctccgcc gtcccccggt ccggcgcgcc cccggtgaga cacgcgtccc
     7681 gcagcagggg ggccgcgctc aaccccgctg acgacgcccg gcgcgccgcc cgggtggccc
     7741 ggcccacccg gccagccccc gcagcagggc gctgcgaccg cggtcgggaa ccgtccacag
     7801 gggcacgccc cgcacgcccc accgttccag cagggcgtcg gcggccagga aaccggtggt
     7861 ggcggcccgt tccatcagcg ccaccggcag gccggtgcgg accaggtcac cggccacgac
     7921 gagacccggg tccggggtgt ggacggccgg ccggccgcgg tagccgccca ccgggaacag
     7981 cgggcagtcg gcgcgccatt cgtgacggac gtcgaggacc gcggccccgc gcgtctcggg
     8041 gtagacgcgg tgcagctgct cgatcaggtg cttctcctcg acgtcccggg gcgtccgcgc
     8101 ccctaccgcg taggcgtgca gttccagcac ggaccccccg gtgcgcgcgg cccagtgcgc
     8161 ggcctcgtcc tcccagcgct ccagcacact gacgttgtcg agggtgggga acccgccggt
     8221 gcccaggaat cccggccggc cgggggccac gggccggtcc agccacagcc gggtcaccag
     8281 gaagggcggc gcgttgcgca gccgggcgat ccgctcgcgc cacggggcgt cgcccagccg
     8341 gtccgagcgg cccacgacat ggcgcagccc cgcggtgtcc agggcgagga cgacagtgtc
     8401 gtgggagcgc tcgtcccggt cggtggcgac ccggtagccg ccgcccggga ccggtgcgat
     8461 gtggtcgacg gccgtggagg tgcgcagttc ggctccgtgc cgtcgcaggt ggtcggccag
     8521 cgggtgccac agggcggacg ggaagggcgc ccggggcacg tcgaacagca ggccctcggc
     8581 ggagcccagg aagtagatgt ggaacatcag cgccagctcg gccgccgaga gctcccgggg
     8641 gtcggcgaag aagctgcggg agaacacctc gaacgccagg tggcgggccc gggcggggaa
     8701 gcggacggcg tcgaggaagt cgtgcgcgct gatgtggtcg agccggtcgt agatctcggg
     8761 gacgcggacg tcgagcaacg gcagggccgc caccgggccc atccggcgca ggtcccgcac
     8821 ggtgaaggac gggctgagcg cggcgaagcc cagggcgctc cacggcgggg tgcgcgggac
     8881 acggcggaag ccgtcccgca tcccgtcggc gtgcagcagc ggatagtcgg gcagggcggt
     8941 gagccggcgc aggccggggt cggtacggcg gagcagcgcg cgcaggttgt agtactggcg
     9001 gaagaaggcg tggaagccgc ggctcatggt caccggggtg ccgtcccgga gacgggtcgg
     9061 ccagcctccg gcgcgcccgc cgaggtaggg ctgccgctcg tacagcgtga cggccacccc
     9121 gcgttcggcg agcgcggtgg cggcggcgag accggcgatg ccgccgccga cgacggcggt
     9181 cgtgggacgg ggaccgtcga cgcgcggctt cccgggccgg gccggcagca gccgggcccg
     9241 ccggtcccgg ccgtgccggg tgtgctccgg gtggccggcc cggttcatcg ggcggcctcc
     9301 gggcggcggg cgacgaaggt gtgggcgatg ccggtctgcc agcccggcag gggcagggcc
     9361 cggacgtgcg tgaagccggc cgcgcggacc cgggcggcga agcggtcggc ggtgtcgaac
     9421 tccaggacgc tgcgccacag atgacggtac agccggccgt ccccgaggac ggacgccacc
     9481 ggctgtacga gaccgcggca caccgcggtc cacaccgcgc ggtcggcgcg gcgcccgctg
     9541 agggcgtact cgtgcacgcc gagccggccg ccgggcgcga gcaggtcgcg cacgccggcg
     9601 aggacggcgt cggggtcgga cacgttgcgc agcaggtagg cggcgaagac cgcgtcgaac
     9661 ggtccggtca ccccggcctc ggccaggcgc tccgccggtg cccgcacgaa cgtgaccgcg
     9721 ccggcccagg gcttggcggc ggcccgccgc agcatgccgg cggaggcgtc gacggccgtg
     9781 atgcgcgcgg ccggcagggc ggcgcggagc gcggccgtcg aggcgccggt gccgcagccg
     9841 aggtccagca ggcgcaggcc cgccccgtcg ccgggcaggc cgagccgccg taccgagcgc
     9901 cggagatggg cgcgatagcc ggggttggcg gcggtcagcg cgtcgtagct gcgggaggcg
     9961 tggtcgaagg cggcggtgag gtcctcgtcg cgcagcaggg tcatacggtc tccaggggcg
    10021 ggggttcggg tgcgggccgg tcgaacgggc ggcggggcag gcccggcagt tcgagggccg
    10081 agcggagcat cgggccgatc ggggtgcgca ggccgacggc gaggtcttcg cgcagccggg
    10141 tgcgcccgtc gaggaagcgc agcagccggg gtgcgggtac gcggcggaac aggtcgcaga
    10201 acagcgcggg gccgtcgacc cggccgccgg ccagggcgcg cagcagcacg gcgtccatgg
    10261 cgcgggagcg ggcggagtgg gcgggcggcg gcacgggccg ctgtccccgg cgcagggcgg
    10321 cggcgacggc ccgggtctgg cgttgcagtc cggcgaaggt gtagccggtg gcgggacggg
    10381 tcgcgccgcc cgccgcgccg atacggaaga cgcgggcccc gacccggcgt ggcatcgggg
    10441 cgtccgtcat ggggatgacc ccggtctcgg tggccaggac ctggctgtcg ccgaggcgca
    10501 gaacgtcgtg ggcgtaggcg cgtaccgccg cctcgtagcc gctgccggtg aggagccggg
    10561 gggagaactc cgtgtactcg acgagcgcct cgcggggtcc ggtgggcagg acgtatccga
    10621 acgacaggcc ggtggcgggc tgggcggtgc ggaagtccat caggtcgacg gtgccggggt
    10681 cgaaggccgg ccgtgcggtg cggacgaacc agccgtggaa gtgctggagc agtgtggtgc
    10741 gggcggcggg caggctgccg aggggccggg agtcgaacac ccagcgggcg cggagcacgc
    10801 ccgtcccccc gtcggggtgc cgcagccgga cgtgggctcc gccctcgaac tcctccaccg
    10861 tctccacggt cgcctccacg cgccgcacgt tcgggctgcg cgccaggtcc cggcggacca
    10921 ggtcctcgaa gtcgtcggac cggagcatct tgtaccgcag cggcgcgagg tccgcttcga
    10981 tcgggtcgcc cgtgggaggc cgtacccgca ggtgccgcca actggccgtc agcgcggcgt
    11041 cgaagcggcc ggggccggct tcccagaagc accaggtgcg gcgcgggggg cgcagggggc
    11101 cgggcggcgc gtccaccagg acgacggacg gcgtccgcgg ccctcgccca ggaccggcca
    11161 ggcgatgggc cagcgacagg ccggcggctc ctgcgcccac gacggccacc tcggcctcca
    11221 acacgacggc tccttccgtg ctgcgctgtc cgtgcgtcac ctctcgcgcc gtgggcggct
    11281 gccgccgccc gtgcgcctcg cccgctgtgc gcgtattccc gtccctgcgc ccggacggac
    11341 gcgggtcacc cgagtgcacc cgcgccggtc acggcggggg cgggtggtgg aaggcatggc
    11401 cacggacggc cggccgcgcc ccggtcggtg ccgcatccga acccggtacg cgcgccgacg
    11461 acgcggtgcc gcaccgcttg cgcgctcagg acgagaggaa ccgggatgtg ccccacccag
    11521 gcgaaggaac accatccggc cgcagcgccg cccgccccgc gcccggtgcc gcagccgggt
    11581 tcccccgtcc ggacgaggcc gtacggggga acgggcgcgg cccggtgcac accgggccgc
    11641 acaccgggcg cggcccggtg tgcggcccct ccgggcgcca ccgcggcgcg ggcggccgac
    11701 gcggacgtgc ccgccggccg ggtgcacggg cacgtcccgg gcgaccgtgg ctcccgggcc
    11761 cgggcgctcg acgccccgtt cgccggggag gcggccggac gggccgcgcg gttcccccgg
    11821 gcggccggca cacacccgcc ctcgcgccat ccgtggcgta cgcctcctgc ccgcggcggc
    11881 accggggaga ccgcggtctc gcgcaccggc gccctgctcg gtctgtcgtc ggtctcgcgc
    11941 accggcgccc cgcccggcct gtcgccggcc cccgccctgg cgcaccgcgg gctccgcgcc
    12001 gcagccccct ccccggtcac ccgcggcgcg aaggagagcg gtcgatgagg cggacgctgc
    12061 ccggacgcac cgaccacgtc gtggtggtgg gagccggtct cgccgggctg tcggccaccc
    12121 tgcacctgct gggcgccgga cgtcgcgtca ccgtcgtcga gcgggatccg gtgcccggcg
    12181 gccgggccgg acgcctggac ctgggcggct accggatcga caccggtccc accgtgctga
    12241 ccatgcccga cctcgccgag gaggccttcg cggccgtcgg cgacagcctg caccggcggg
    12301 tcgaactggt ccccctgcac cccgcctacc gggcccgctt cgcggacggc agcacgctcg
    12361 acgtgcacac cgacgccgac gcgatgacgg cggaggtgga gcggttcgcc ggctccggcg
    12421 aggcggcggg ctaccggcgg ctgcgcgact ggctggagcg gctgcaccgg gcgcagatgc
    12481 gccgcttcat cgacgcgaac ttcgactccc cgctgaacct cctcaacagc gacctggccc
    12541 ggctggccgc gctcggcggc ttcggccggc tggacgcacg gatcgggcgg ttcctcaggg
    12601 acgaacggct gcgccgcgtc ttctccttcc aggcgctgta cgcgggcgtg ccgccggccc
    12661 gcgccctggc cgcgtacgcc gtcatcgcct acatggacac cgtcgccggc gtctacttcc
    12721 cgcggggcgg catgcacgcc ctgccccggg ccatggcgga cgccgccgcc gacgcgggcg
    12781 ccgacctgcg gtacgggcag cgggtgaccc gtctggaacg ctccggggac cgggtcaccg
    12841 ccgtcgtcac ggaccaggac cgcatcccct gcgacgccgt cgtcctcacc ccggacctgc
    12901 ccgtcgccta ccggctgctg ggccgccggc cccggcgccc gctgcgcctg cggcacgcgc
    12961 cgtccgccgt ggtgctgcac gccggaaccg accggacctg gccgcacctg gcgcaccaca
    13021 ccctctcctt cggcgcggcc tggcggacca cgttcgacga actcacccgc accgggcggc
    13081 tcatgagcga tccgtcgctc ctcatcaccc ggcccaccac caccgacccc gggctcgctc
    13141 cgccgggccg ccatctgcac tacatcctcg cgccctgccc caacaccgac atcggaccgg
    13201 acgccgccgc gtggggcgac ctcggccccc gctaccggga cacgctgctg cgggagctgc
    13261 aacggcgcgg cctggacggc attgaggccg ccgtccagga ggagtgcctc gtcacccccg
    13321 ccacctggca ggccgccggc catgccgcgg ggacaccctt ctcggccgcc cacaccctcg
    13381 cgcagacagg gccgttccgg ccgcggaacc tggtccgggg caccgagaac gccgtcctcg
    13441 ccggctgcgg caccacaccg ggcgtcggcg tgccgaccgt gctggtgtcc ggcaagctcg
    13501 ccgccgcacg gatcaccggc ccgcctccgg cacccccact gccgcgcgcc gcggcggcgt
    13561 acggggaggc ggccggcgta tgacggaccg tgaactggac gcggcgggga tcggcgaccc
    13621 ggcgctgcgc gcggcctacc gccactgccg cgccctgaac gcgcggcacg ggaagaccta
    13681 cttcctcgcc acccggctgc tgccggtcga gcgcagaccc gccgtgcacg ctctgtacgg
    13741 cttcgcccgc tgggccgacg acatcgtcga ctgcctcggt cccggcgcgg acaccgggcg
    13801 gcgggccgcg gccctgacgg gactgcggcg gagcctggag gaggggctgc gggacgggca
    13861 cagccacgag ccggtggtcc tggcactcgc cgacaccgca cgccgttacg ggatcgagcc
    13921 cgcgctcttc cacgacttca tgtccgcgat gagcgccgac ctgaccgtga ccgactacgc
    13981 cgactacgcc gccctgcgcg gctacatgca cggctcggcc gcggtgatcg ggctgcagat
    14041 gctgccggtc ctgggcacgg tcgtaccgcg cgaggaggcc gccccgtacg cggcggaact
    14101 gggcgtcgcc ttccagctga gcaacttcct ccgggacgtg ggcgaggacc tggaccgggg
    14161 gcgggtctac ctgcccgcgg atctgctggc cggccacgga gtggaccggg aactgctgcg
    14221 gtggagccgg gacaccggcc ggcacgagcc gcggatcacg tccgcgctgc gcgagttcga
    14281 ggcgctgacc cgcggtgtct accgtcaggc gctgcccggc ctcgccatgc tggcgccggt
    14341 gtcgcgcccc tgtatccgga ccgcgttcct gctgtaccgc ggcattctca acgcggtcgc
    14401 ccgggacggc tactccgtgc tgcaccgccg cgcggtggtc ccgcgccggc gccgcgcggc
    14461 ggtcgccgcc gacggtctgg cgcgcgcggt cgccgcgcgg ctgcgggccg ggcgttcccc
    14521 ggcgccgtgt ccgccgcacg ctccggcacc cggcacaccg tgcccgccgg ccgcgaagga
    14581 ggtcatgtga aacccgtccc gtccggccgg cgcggccgtc ttccgctctc gctgcgccgg
    14641 cgcccggtgc cctgggagcg gcagcggccc acctggcggg acgccgggcc cgcggtgatc
    14701 gcgcgggcgc tgaaacgggc cgaggcccgc ccgtccggca actggtacgt ggtcggcgcg
    14761 tcgggcgagc tgcgggcgga ccgtccgctc gcccggaccg tcgcgggaca ggaggtggtc
    14821 gtctggcgcg gccccgacgg ccgtccggcc ggcggcccgg gtgtctgccc ccacctcggc
    14881 gcaccgttgc gggacagtcc cgtccgctgc ggcaccctgg tgtgccactg gcacggactg
    14941 gccctgggcg gcacgccgca cgcgggctgg gttcccctgc cggtgcacga cgacggcgtc
    15001 ctgctgtggg tacggctgga cgagctgggc ggtgaggcgc cgctggacgc accggtcgtc
    15061 gcgcggcggc ccgagcgggc gacggcgctg acagccgtct actccggcac gggagtctgc
    15121 gaggtcgagg acatcgtggc caaccgcctc gacccgtggc acggggcgtg gttccatccg
    15181 cacgcgttcg ccgacctcac cgtggtcggc tcacccgacg gcgcggacgg gccacccggc
    15241 accgtggccg gctcgtccgg catcgcggtc ggctcatccg gcaccgtggc cggggcatcc
    15301 ggcatccgcg gcaccgagga cgccttcacc gtggacgtct ccttcaaagt ggcggggcgc
    15361 ctggtggtcc cggtgcgggc cgtgttcacg gctcccgaac cgcgcacggt cgtcatgcgc
    15421 atcaccgagg gggagggcgc gggttcggtc gtcgagaccc acgccacacc cctcggcccg
    15481 gacgagctgg gccggccgcg gaccgcggtg accgaagccg tgctggccgt gtccgaccgg
    15541 ccgggcttcg cggtcgtccg ccgggcggca cccctgctgc ggcccctcgt ccgcgcggcc
    15601 gcggggcgcc tgtggcggga cgacctcgcc tacgccgagc ggcgctggca cctgcgctcc
    15661 acgggacggt tccccggctg atcccgcgcg tcggccgccc ggcgcgccgg cctccgcggc
    15721 gtcggccaag aggcaacgtg cctcacagcc gacctgatcc gaacgacagg ccctacccgc
    15781 cccgcgccgc caggcgctcc cgctgcggga cgacggtgta cgcggggtcc tcggcggagg
    15841 ccaccccggc gtggaacacg ccgaaccgca gcgccgccga gccggtgagc agcgcggtac
    15901 cggccgccat ggcgaggcgc cggtcccgcc cgcggcacag cgcgagcacc gcaccgcccg
    15961 ccgtgagcag ttccgcggcg cgcaccagca cccgcgcccg cccttgcccg aagggctcgg
    16021 cggccaagcc catgcgccgc cgcatcgccc ggaaggcacc cagttccagg gcggccccga
    16081 gcaccgccag ccggcgggcc ggccccgcct ggacgaccgg gacggcggcc agcgcaaggc
    16141 cggccgccgc cgtggcggcc gagcccgcga agacgaacgg cagctcacgg tagccctcgt
    16201 gccacgcggg caccgccgtg tccgacagca gcaccgccgt gtacgtcgcc acggccgggc
    16261 cgaggacggc ggcggccacc gtggcggccg agcccagcag ccggtaccgg cccgccacct
    16321 cggtggccgc cgccgtcagc gtcagcggcg cgtaccccgc gagcagccac gagcccacgc
    16381 tcatcgggga ggtcggcttg atcacccgga gcatgttcag gaaccgggcc ggccggccca
    16441 ggtcgtgcac cagcgccgcc agcgacagcg agaccgcccc ggccgcgccc agcttcgccg
    16501 gtgccgcgag ccccggccgg ccggtcagct gtcccccggc cgcgagcagt gaggacgccc
    16561 cggccagccc gccgaggtac agatacccgg cgatgtccag cggcttccac ggcggcttgg
    16621 tgagcacggg ggtgccgtag tacgacgcga actcggcgtc cggcaccacc ggccgctcgc
    16681 cccggccgtg cccgcgcctg cggcggccca cgtgcgcgcc gggcaccgcc tcccggccgg
    16741 gccgcgcgcc ccgcacgccg tcccgggtga cgtccgaccc gctcatcacg gcctcctcac
    16801 gcgggcgctg acgctcctgg cggcctccgc gcggaccacg cgggtcgtcg ccgccttccg
    16861 gcgggcctcg ccggtcatcg ccgcctccgc gcgaaactgc cggccgcgag cgcggtcagc
    16921 gagacggcgg ccagcgccgc ctgccgccac atggcgggca ggtcccgggt ggtgaccacc
    16981 gggtccgggg gcaggccgta cacctcgggc tcgtccagca gcaggaagaa cgcgccggcg
    17041 ccgccgaccc cgtcgtccgg gctctcgccg tagaggcggg cgtcggtcgc gccggccgcg
    17101 tgcagctgcg ccacccgggc ccgtgcccgt tcccgcagct cctccagcgg gccgaactgg
    17161 atggagtccg tcgggcagga cgtggcgcag gcgggctcca ggccgacgcc gagccggtcg
    17221 tagcacaggg tgcacttcca cacccggccg tcgtcctcgc gtcggtcgat gacgccgtac
    17281 gggcaggcgg gcacgcagta gccgcagccg ttgcagatgt cctcctggac gacgacggtg
    17341 ccgaactcgg tgcggaacag cgagcccgtg gggcacacgt ccaggcaggc cgcgtgggtg
    17401 cagtgcttgc acacgtcgga ggccatcagc cagcgcagtc cggtcccgcc gtcgggggag
    17461 gccggggaga tccgcgcggc ggcggtgaag acgtccacgt cgccggcgtc gtcctgggcg
    17521 gccgacggct ccggcccgcc gaacggcccc cgttgctcca cgaacgccac gtgccgccag
    17581 gcgtcggcgc cgaggccgcg cgtgttgtcg taggacatgc cggtcagcgc gagaccaccc
    17641 gccgggatcg cgttccactc cttgcaggcc acctcgcagg ccttgcagcc gatgcacacg
    17701 gacgtgtcgg tgaagaagcc cacccgtggc ggtgcgtccg ggtagccgga ggcaccggcg
    17761 acgtccggct gcggaccgta cagggcgttg ccgcggtcct cggcgccgtc acccatgccg
    17821 tcctcctcgc ccatgaccgc ccgcccgcgg ctgctgccgg gaccgccacc gcgcgcacgc
    17881 tcatcgtcgg tgttcggtcc cgcacactca gtgctctgct cccgagcctg gcacgagtgc
    17941 tcccgctccg cgcgcccgag agggtccggc cgcttcgtac ggctgacggg gcgggccgct
    18001 cccggctcac cgggtacggg gcggagccgc ccggccggac ggttcagtcg gccgccgcgg
    18061 ggccgagcgg cacggtggcc gagacccgct tgccccggga cagccaggtc acctccagcc
    18121 cccgggagag catcgccacg agatgcaggc cgtggccgcc gacccgccgg gggtcgggag
    18181 gatgccgccg gggcggctcc ggggaggtgt ccgtcacggt gacgcgcagc gcgctcgcgc
    18241 cgggcagcag ctccaggcgc agggcgcacg ggccgggcgc gtgctgggcc gcgttggtga
    18301 cgagttcgct gacgacgatc tgggcatcct gcaccggccg ccgcccgagc gccggccgga
    18361 cccgcgccag cagggcggca acggcgtctc tggcctcggc gatgctggat acaccggtgc
    18421 cccaggtgcg gctgtagcgc aggggcgccg ggcggtcctg cgtcgtcgcg tgggtcctga
    18481 gcgggatgtc cataccttgt ttgccctttt cctctggggt caggggccct tcctgtgcac
    18541 aggggggtcg tgccgtccct gctcggttac ccccggttcc ggcagtcaag gggacgtccg
    18601 cgaggaatcc tccggatgcg cgccgggggg tcacacagcg gaacgggtcc ggagatcggc
    18661 ttccgctgat ctccggaccc gttccgcagc cgaatcggcg cgtgcacgcc tcagtgcttg
    18721 aagacgtcct tgatcttctc cttggcctgc cgggcatccc gcgggcgccc ttcatgcggc
    18781 cctcgtcctc catgcgctcg ttaccgaggg cgcggcccgc ggcctccttg agcttgccct
    18841 tggcctgctc cgtcttggcc ttcgccttct tgttgccggc catcgcggct cacatcctca
    18901 gatcgacgtg gtctgcggtc gacatccgga ttgccgctcc accggagtcc aaaccgatcc
    18961 gcgtccgacg gcccctcctg gcgaacgcaa cgcgtccgtc accgccaccg cccctgcctc
    19021 gaagcgctcc cctggccagc atcagcgggc ccgcccacgg ccacgccgtc gacgaagccg
    19081 tcacctggct tctcgacccc agtacaccga cggcttacgg ggcaggtggc accgcactgc
    19141 cgatgagaca gcgcacgccg tacacgcccg cccgttccgg cgagtgccct cgacgatgcg
    19201 gtcggtgtgc agggcaccgg cggtcaggcc gaactcggtc ggggccccgc cgacagcgaa
    19261 acactcgaac tcaccgagcg cgacgagggc ctcgccgccg cacgcgccgt gaaccgggac
    19321 ttgatggctc actgagccga tgacgggggg tgccggacta cgccggagac ctgccttctg
    19381 ccagcggcag aacaccggcc cgaccgggct cgacgatcac tacagtccag gctcatgacg
    19441 gtgacaacac gcacgatcga atacaccgcc gacggcctga cgatgatcgg gcacctcgcg
    19501 ctcccggccg gtgacgaccg ccggcccgcg gtcctggtcg ggcccgaggg gatggggctc
    19561 agcgacgtcg agcgccgccg ggccgatgcg ctcgccgagc tgggatacgt ggccctggcc
    19621 ttcgacctcc acggcggacg ctatctgggc gaccccgagg agatgctggc ccgttgcctg
    19681 cccctgctcg ccgatcccga ccggatgcga ggcatcggcc acgcggcgct cggcgtgctc
    19741 cgcgccgagc cgcggaccga ccccgaccgg atcgccgcgg tcggctacgg caccgggggc
    19801 gccatcgcgc tggaactcgg gcgcgacggc gtcgacctgc gcgcgatcgg gacagtcaac
    19861 ggactgacca cgggccggcc gggcgagacg gcgcgcatcc actgcccggt gtgggccggc
    19921 gtcgggtcgg aagacccgat catgccgccc gcgcaacgga acgcgttcac cgccgagatg
    19981 caggctgcgg gcgtcgactg gcgcctcacg gtctacggcg gtgccttgca cgccttccat
    20041 cacccgacgg tcgaccaccc cacggttccc ggcgtcggct accacccgca gcatgcgcgg
    20101 cgagcctggc gtgacgtcgt cgacctgctc gccgagtgcc tgcccataac ggagtgatcc
    20161 ggtcggcaac cgcgactcga tccatctcca ggaccagcgg ctgagctgac ccgagccgtg
    20221 ctcggggcgt tccggctggg ctcgcaccac ctgctcgaat accgcacccg cacgatcttt
    20281 cgggcgccct cagcggaccg cttcctccct ccgcgccggc cgagtggaac cggctgatcg
    20341 atctcggcaa gcaggaggta cgccgcctgt cggacgggcg tcctccccat gcaccggccc
    20401 aaaagggttc agtgacgatc cgactggacc gcggtcagtc gatgccttcg acgatgcgga
    20461 agtcgcgctc gacgccgtcg gagagggcga tcagcgcctc ctggtaggcc gcactctcgc
    20521 gtgccgcgac ggcctgctcg aagctgtcga actcgatcag cacggtgcgc tcggcgattc
    20581 cggcgtcatg cgccacgacc cgaccgccac ggacgaggac ccgaccgccc ccggcctcga
    20641 cggccaggcg agccagctcg ttgtaagcag ccagcttctc aggatccgaa atggtgcggt
    20701 agacgctgac ccagtagccc ttgggcatgg aacctccagt gctgtgataa gtgcatctga
    20761 ctttgtgatg agtgcatccg acttacgggg tggtcccgga cgagcgtcgg cgggcgagag
    20821 cgaggccggt cagcgtcgtg atcgccatgg ccccgacgcc gaccagggcc gcggtggtgt
    20881 aggcgctgtc gtcggggaag aggtggccgg ggccggtgcc cgcggcgagg atcaggccgc
    20941 cgatggcgct gcccagggag tacccgacgc tgcggacgac gtagttgaag ctcatggcgc
    21001 tcgacgtctc gctcttgggg gtgacggcca ggatgacgcc gggcatcgcg gccgagaagc
    21061 cgccgacgcc gaagccgagc aagcccatcg ccgcgaacag ttcggccagg tccgaccggg
    21121 ccgccgcgaa cagggcgaac ccgccgccga ccacgacggc actgccggcc aggagcaggg
    21181 ggtcggcgat ccgcttccgg gcccgcggcg tgagcttgcc ggcgacgaac cccagcaccg
    21241 agaacgggat gaggaccagc ccggcgacga aggtcgtgag tccgaagccg tagccggcgc
    21301 cgcgcggcgt ctgcgcgtac cgggtgatga gcgtgagcag gaggtacatg ccgatcccgc
    21361 cgacgaacat ggcgaggttc gccccggcga ccgccgggtg ccgcaccgcc cgcacatcga
    21421 ccaggggcgt cgtgctgcgc agctcgatga cggcccagac gcagagcagc accaccgcga
    21481 cgacggcgag acccgccgcc acggcgaggt gccggctcca gaggttccgt tcgccggcga
    21541 ggaacagcac caggagcagc gcagcggcca ggacgaccgc gcctgccacg tccacctggg
    21601 ccaagcggcc ttcgggcgct tcggggaggg agcgccacgc tgtcaggagg gcggcggccg
    21661 tgaggaccag gccgaggccg taggcggccc gtaccccgcc gacctcggcg agcagtgcgg
    21721 ccagcgggta gccgacgccg gccccgatga ccgagaccac cgagatcagg gcgatgacgg
    21781 ccgcgctgcg ctcctcgggg aggtggtccc gggccacgcc catcatcagg gccgtcagcc
    21841 cgagcccgac gccctgggcc gccctgccgg ccagcagcca cgcgaacggc agcggcagca
    21901 cggtgagcgc gctgccggcg acgacgaccg ccagcgtggc gaggatcgtg gcccgccggt
    21961 gcgggccggc cccgagctgg cccaggaccg gcgtggcgac ggcgccgctg agcagcgcgg
    22021 cggtcagcgt ccactgcgcg ctgcccagcg agacgtggaa cgaggtcgcc acgctggtga
    22081 tgagcggcgt cccgaggctg gcgatcgccg ccacgaccag agagaggaac atcagggcgg
    22141 ggaccagcag ccgcgcctcg gaacgcgcca ccgggaacgc ctccaccgcg accccgccga
    22201 ccggccgccc ggtcactgct tcggctcttc gcggtcctgg ctttcgagct ctgccagatg
    22261 cctcagcgcc ggaagggccg ccaccagcgc ctcgacctcg tcgtcggtga gctcgccgat
    22321 caaccgctcg aacgcgtgga tgcccgcctg gcgccgcgtc cggacgtagg aggcgccggc
    22381 ctcggtcagg cacaccagcg tgacccgctt gtcggacgcg tcgccccgcc gctcgaccag
    22441 gccggactcc tccatcaccc ggaccagggc cgtcatcgcg ggctgggtga cgccctcgac
    22501 cgcggccaga tcggtgatgc gccgcgggcc ggttcggtcg agggtggcca gggtggcggc
    22561 ggacgtcagg ctcatgtccc ggggcaggcg tctcacggcc ctggtggcca ggccgtagag
    22621 ggctgccccg atggcggcgg acgcgccagg agcggtgtct tgacgactca tgcccgaagc
    22681 ataacacttt tatattcata gcttatgtaa atggtcgacc gacgccggct ccaccggctg
    22741 cgctcggggg ccgagggcag catcagggag ggcgtggacg gccaccgact tgcggtcacg
    22801 ccgctgctgg accggggtga gcggccggac cttcacgccg tgacggtgtc agagcgggca
    22861 ggccggcggc tcgggctgtg ttcttcgagt agccctgcca ctagccctgc cacctggcag
    22921 cggtgtcacg ctgccgaggc cgccacactc atcggacgaa gcgcacttcg gggtagtccg
    22981 aggaagactt gtccagcaga tgtcgtggcc ggcctagcag gtgctggtcg aagaacgccg
    23041 tgacgtaggc acgctgggct gcggtgctcc gctcggggtc cacggtgccg atgaactgct
    23101 cgcggttctg cgccgggatg tccaggtgct cgtccagagc gggcacgatc gtctgagcgt
    23161 cggtgtagct gaagtggccg cccccctcca gcctcaagtc gcgcttccag ccggtcgagc
    23221 ggtcccagaa cgactgccag gacggcttgt tcaggtgagt ctgattcgcc ttgcccatga
    23281 gcatgaacgg gcggtcgagc ccttccaggg ccacagggag gaattcggtg ctgctgtact
    23341 ggagcgtgcc gtccatgttg atgcccgcgt cgatgcgacg gtccgcgcgc atggtctcgg
    23401 ccgcggtgat acctccggcc gaatgaccgt acattccgat ccggtccagg tcgagcgccc
    23461 cgcccagccc acggggtaga cggcgcccct cggcatcggg gttgcggccg gcccgcagca
    23521 ccgcaagctg gtcaaggacg aagcgggtgt cccgtacccg ggtctcgaca gccttcttga
    23581 ccgtctcggc tccggtcatc ggctccttct gcaactcgac gcggccgttc gggaactcca
    23641 ccggagtggt ctcatgggtg tggtccacgg tgaccaccac gtagccgcgg ctcgccagtt
    23701 ccacggccgt cgaggtgcca agcgcgcggg ggacccccag acccggcgag tacagcagga
    23761 ccggccgcct gctgcggtcg tcggcagggg ccatcgaggc cgcgtccgtc cgggtggcgg
    23821 cccagtccac ctcgccggga cgggccagcc cgaacgagcc cgcctcgtcc acgaagcgcg
    23881 cggcgccggg ccgcaggtac ggctggcggg agtatccgct cactgaacgc gccggatacc
    23941 acacactgac catcagctcc cgttccctgt cggcgaccca gggatcgggc cggtcccggt
    24001 cgacgagatg aagttcagtg ctcccgaccg cctgccgccc cgtcggctcg ggcagctcga
    24061 accgcacggc accatgagct gccgagggta agggctcgga cgaggaggcg gcggaggcgg
    24121 ccgtgcccga accggcggac agggtgagga caagagccac cgcggtggtt ctacctgtat
    24181 ggaatcgcat gccagccaat ctggccccgg gccccgcatc gacacgtccg ccgacaggcg
    24241 gagccgatcc ctggcattcc cctgagcacc ttctccccgc tgttcagggt cggggttacc
    24301 tcggggtccc agatgaccaa cgtcaagggg tcgtccggtt ccgatgggcc ccggagcggc
    24361 acctactcgt ttcggcgagc ccggggtgcg aagggaaccc ggcctacgtg tacccgctct
    24421 atgacgtcga cgacatctcc tccgagcaaa gggcctgggc gacgcggtga aagctttccg
    24481 agccgctcat aatccagggc ttcggacggt tctcggtgcc cttgtcgccg gtgaggatgc
    24541 aggcggcttg cggctgctga acgctgatgc cccggatcca gtcgccgtcg
//
