LOCUS       NZ_AP024135            12850 bp    DNA     linear   CON 08-NOV-2024
DEFINITION  Streptomyces sp. EAS-AB2608 strain NBRC 114648 chromosome.
ACCESSION   NZ_AP024135
VERSION     NZ_AP024135.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. EAS-AB2608
  ORGANISM  Streptomyces sp. EAS-AB2608
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Kitasatosporales; Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Okubo,S., Ena,E., Okuda,A., Kozone,I., Hashimoto,J., Nishitsuji,Y.,
            Fujie,M., Satoh,N., Ikeda,H. and Shin-Ya,K.
  TITLE     Identification of functional cytochrome P450 and ferredoxin from
            Streptomyces sp. EAS-AB2608 by transcriptional analysis and their
            heterologous expression
  JOURNAL   Appl Microbiol Biotechnol 105 (10), 4177-4187 (2021)
   PUBMED   33944982
  REMARK    DOI:10.1007/s00253-021-11304-z
REFERENCE   2  (bases 1 to 9320785)
  AUTHORS   Okubo,S., Ena,E., Okuda,A., Kozone,I., Hashimoto,J., Nishitsuji,Y.,
            Fujie,M., Satoh,N., Ikeda,H. and Shinya,K.
  TITLE     Direct Submission
  JOURNAL   Submitted (28-OCT-2020) Contact:Shinya Okubo Eisai Co., Ltd.;
            Tokodai 5-1-3, Tsukuba 300-2635, Japan
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Newbler v. 2.9
            Genome Coverage                   :: 53x
            Sequencing Technology             :: Miseq; PacBio RS II
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_019703895.1-RS_2024_11_06
            Annotation Date                   :: 11/06/2024 09:16:33
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,174
            CDSs (total)                      :: 8,084
            Genes (coding)                    :: 7,890
            CDSs (with protein)               :: 7,890
            Genes (RNA)                       :: 90
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 194
            CDSs (without protein)            :: 194
            Pseudo Genes (ambiguous residues) :: 0 of 194
            Pseudo Genes (frameshifted)       :: 87 of 194
            Pseudo Genes (incomplete)         :: 132 of 194
            Pseudo Genes (internal stop)      :: 10 of 194
            Pseudo Genes (multiple problems)  :: 32 of 194
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 13:41:52
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 7061524
            Orig. end                         :: 7074374
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            AP024135.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..12850
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="hydrogen-cyanide"
                     /region_number="28"
                     /rules="(Fer2_4 and cds(Pyr_redox_2 and Fer2_BFD) and DAO)"
                     /tool="antismash"
     cand_cluster    1..12850
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(Fer2_4 and cds(Pyr_redox_2 and Fer2_BFD)
                     and DAO)"
                     /kind="single"
                     /product="hydrogen-cyanide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..12850
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[5000:7850](-)"
                     /cutoff="5000"
                     /detection_rule="(Fer2_4 and cds(Pyr_redox_2 and Fer2_BFD)
                     and DAO)"
                     /neighbourhood="5000"
                     /product="hydrogen-cyanide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(5001..7850)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="(Fer2_4 and cds(Pyr_redox_2 and Fer2_BFD)
                     and DAO)"
                     /neighbourhood="5000"
                     /product="hydrogen-cyanide"
                     /protocluster_number="1"
     misc_feature    299..314
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.81"
                     /tool="antismash"
     gene            complement(540..1964)
                     /locus_tag="K6K39_RS31250"
                     /old_locus_tag="EASAB2608_06391"
     CDS             complement(540..1964)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1038: phenylalanine-specific permease"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004992379.1"
                     /locus_tag="K6K39_RS31250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EASAB2608_06391"
                     /product="amino acid permease"
                     /protein_id="WP_059246521.1"
                     /transl_table=11
                     /translation="MHSTGTVPQSAPAPAGSPAESPTALAEDPHGNNGRHARRFGLPVA
                     TALVMGNIIGGGIFLLPASIAPYGTVSLVAFGVLTVGAIALALVFGRLAARDPRTGGPY
                     VYAREAFGDFAGFLAAWSYWITTWVSNAALAVAAVGYLDVLIPVNDHRWTACLAALALQ
                     WLPALANFAGTRYVGAVQLVSTVLKFVPLLLVAVGGLFFFDPDRLGPFNAGDQSPIGAV
                     SAAAALLLFSYLGVESAAVSAGEVRDARRNVGRATVIGTAGAALVYLLGTLSVFGTVPH
                     DRLVDSTAPFSDAVNTMFGGSWGGTAVALAALVSMTGCLNGWTLLSAQTPYAAARDGLF
                     PSAFTRRRRGVPTVGVGVTVVLASLLTVYNYLSGSGKVFEILVLVTTFTATVPYLLATA
                     AQIYHLVSGRAVDRARLVRDSVITAVAAAFSIWLMAGAGYAAVYQGVLFLFVGVIVYAV
                     LAARRQRKQTQAVEVP"
     misc_feature    complement(1982..1996)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 16.7"
                     /tool="antismash"
     gene            complement(2163..2849)
                     /locus_tag="K6K39_RS31255"
                     /old_locus_tag="EASAB2608_06392"
     CDS             complement(2163..2849)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1071: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014676290.1"
                     /locus_tag="K6K39_RS31255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EASAB2608_06392"
                     /product="GntR family transcriptional regulator"
                     /protein_id="WP_223283711.1"
                     /transl_table=11
                     /translation="MAQNTRGAEMPALPRLGGRRSSYRERVADALRAALIAGELRPGEV
                     YSAPSLAARFGVSATPVREAMLDLAKEGLVDTVPNKGFRVTVVSDQQLDEYTHIRALIE
                     IPTVVELARTADRVSLEALRPAAREIVTAAVAGDLIAYVEADTRFHLGLLALAGNAHLV
                     EVVADLRKRSRLYGLTALVEAGRLLASAEEHLELLDALLERDEKAVHAVMTRHLGHVRS
                     LWAAPD"
     misc_feature    2844..2854
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: strong, score: 22.05"
                     /tool="antismash"
     gene            complement(2882..3883)
                     /locus_tag="K6K39_RS31260"
                     /old_locus_tag="EASAB2608_06393"
     CDS             complement(2882..3883)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010358096.1"
                     /locus_tag="K6K39_RS31260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EASAB2608_06393"
                     /product="proline racemase family protein"
                     /protein_id="WP_059246523.1"
                     /transl_table=11
                     /translation="MRSTLVLHAVDSHTEGMPTRVITGGIGTIPGATMNERRLWFREHR
                     DDVKQLLMNEPRGHSAMSGAILQPPTRPDCDWGVVYIEVSGYLPMCGHGTIGVATVLVE
                     TGMVAVTEPVTTVRLDTPAGVVVAEVAVADGAARAVTLRNVPSFAAGLDREVTLPDGRT
                     VGYDLAYGGNFYAILPLDALGLPFDRARKDDILAAGLSLMEAINEQAEPVHPEDPTIRG
                     CHHVHLYAPGATARHSRHAMVIHPGWFDRSPCGTGTSARMAQLHARGELPLHTEFVNES
                     FIGTRFTGRLLGTTEVAGAPAVLPSFTGRAWITGTAQYLLDPTDPFPRGFVL"
     gene            complement(3896..4792)
                     /locus_tag="K6K39_RS31265"
                     /old_locus_tag="EASAB2608_06394"
     CDS             complement(3896..4792)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003996366.1"
                     /locus_tag="K6K39_RS31265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EASAB2608_06394"
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="WP_221335166.1"
                     /transl_table=11
                     /translation="MSEAQHRPWRGILVATALPLREDLSVDHDRYAEHCAWLVANGCDG
                     VVPNGSLGEYQVLTPEERARVVETAVAAIGGERVMPGVSAYGSAEARRWAEQAGEAGCT
                     SVMLLPPNAYRADERSVLAHFAEVAKAGLPVVAYNNPIDTKVDLVPELLARLHGEGLVH
                     AVKEFSGDVRRAYRIAELAPELDLLIGADDVLLELAVAGAKGWVAGYPNALPRASAELY
                     RAALAGDLTTALPLYRQLHPLLRWDSRVEFVQAIKLSMDVVGRYGGPVRPPRVQLPPEQ
                     EAAVRAATEKAVAAGLA"
     gene            complement(5001..6398)
                     /locus_tag="K6K39_RS31270"
                     /old_locus_tag="EASAB2608_06395"
     CDS             complement(5001..6398)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hydrogen-cyanide: Pyr_redox_2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hydrogen-cyanide: Fer2_BFD"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1176: alkyl hydroperoxide reductase subunit"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014676293.1"
                     /locus_tag="K6K39_RS31270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EASAB2608_06395"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_221335167.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 2.4e-28, bitscore:
                     98.1, seeds: 64, tool: rule-based-clusters)"
                     /sec_met_domain="Fer2_BFD (E-value: 5.6e-10, bitscore:
                     38.4, seeds: 211, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTEPPRLAVIGAGPAGLAGALAAAARGVRVTLVDAAEQAGGQFYR
                     QPAAALGARRPQALHHQWRTWERLRDGLARHRTAGRITHLTDHHVWCVRRESASGPISV
                     HALLGPAQEEGVTVRADAVLLATGGYERVLPFPGWTLPGVVTAGGAQAMLKGGLVLPGR
                     TVVVAGTGPLLLPVATGLAAAGARVAALVESAGPAALLRRAPALAAQPGKLAEGAGYAA
                     RLLRHGVRTLTRHTVVAAHGTDRLEAVTVAALDRDGRLRPGSARRIPCDTLAVGHGMLP
                     HTDLAETLGCTLSGTAVRVDAEQRTDVPGVWAAGEATGVGGAALALAEGHIAGRSAAAR
                     LHGTAPDPRRWAAAARTRTRLRDFAAALEAVYAPPAGWADRVPDDTVVCRCEEVTAGRV
                     RESAGLLGAPDLRSVKLLSRAGMGWCQGRVCAPAVAGLAGCPLTAGRRPFARPVPLGVL
                     AALPDTD"
     gene            complement(6391..6693)
                     /locus_tag="K6K39_RS31275"
                     /old_locus_tag="EASAB2608_06396"
     CDS             complement(6391..6693)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hydrogen-cyanide: Fer2_4"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003994282.1"
                     /locus_tag="K6K39_RS31275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EASAB2608_06396"
                     /product="(2Fe-2S)-binding protein"
                     /protein_id="WP_086696820.1"
                     /sec_met_domain="Fer2_4 (E-value: 1.3e-28, bitscore: 97.8,
                     seeds: 114, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNPLEWARARPGEPCTVTFDGRPLPALPGQTVAAALWAAGTTAWR
                     STRGTGRPRGVFCGIGVCFDCLVTVNGRPNQRACLVPVRPGDVIRTQEGTGRDDD"
     gene            complement(6690..7850)
                     /locus_tag="K6K39_RS31280"
                     /old_locus_tag="EASAB2608_06397"
     CDS             complement(6690..7850)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hydrogen-cyanide: DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1103: FAD dependent oxidoreductase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014676295.1"
                     /locus_tag="K6K39_RS31280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EASAB2608_06397"
                     /product="FAD-binding oxidoreductase"
                     /protein_id="WP_094372578.1"
                     /sec_met_domain="DAO (E-value: 3.8e-65, bitscore: 219.6,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKRLTCDVVVVGAGMVGAACAWYAARAGLDVRLVDRGPVSGGTT
                     GAGEGNLLVSDKEPGPELELALLSARLWAELAQEHGTAIEYEPKGGLVVASTPRTLAAL
                     EDFVAGQRRAGVTAVPVGGDRLGELEPHMAPGMAGGVHYPQDAQVMPALAAARLARASG
                     AALHGGRTVTGVLRTADGTVYGVRTDRGEIHAPAVVNAAGTWGGDLAALAGVRLPVLPR
                     RGFVLVTEPLPRMVRHKVYAADYVADVASDSAALRSSPVVEGTAAGPVLIGATRERVGF
                     DRSLSLTAVRALAAGAIGLFPFLERVRALRTYAGFRPYLPDHLPAIGPDPRAPGLFHAC
                     GHEGAGIGLAPGTGQLIAHALTGKAPELDLTPFRPERFDTEGGDVR"
     misc_feature    7856..7866
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 17.67"
                     /tool="antismash"
     gene            7981..8103
                     /locus_tag="K6K39_RS41290"
     CDS             7981..8103
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020127454.1"
                     /locus_tag="K6K39_RS41290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="putative leader peptide"
                     /protein_id="WP_260335808.1"
                     /transl_table=11
                     /translation="MTRLAPRTGRTGRTPLRAPLLTSRRHIDLQRVCSAISRHR"
     gene            8331..9218
                     /locus_tag="K6K39_RS31285"
                     /old_locus_tag="EASAB2608_06399"
     CDS             8331..9218
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014676296.1"
                     /locus_tag="K6K39_RS31285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EASAB2608_06399"
                     /product="glutathione S-transferase C-terminal
                     domain-containing protein"
                     /protein_id="WP_086696819.1"
                     /transl_table=11
                     /translation="MSITSLAAVPSAHRTAPVFRGRIGSDARSGHYAVPHRYRLHLSTA
                     CPDGLRLAVGHSLLGLDTRCPVTLLPAVPDGPGGGHAALRPLYEASAHRYTGPALAPVL
                     SDDWSGRIVSTHTPDILRDLDRFRPGGDARLYPSGLESVIEAVERMCGEGVEEAAQRAG
                     RAGADPAERAAALDILLDTLGRLERRLSGEEYLADGRLTAADIELWVTLVQLDTVHRCH
                     LDASAVHRIAGHRALWAYARRLAAHPAFGRHLDLDAIARRHHGRCQGLEAAGAAVQILD
                     WASHAADASDASRR"
     regulatory      9296..9405
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00634"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00634"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="SAM riboswitch class IV; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /regulatory_class="riboswitch"
     gene            9762..10751
                     /locus_tag="K6K39_RS31290"
                     /old_locus_tag="EASAB2608_06400"
     CDS             9762..10751
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1096: polar amino
                     acid ABC transporter, inner membrane"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014676297.1"
                     /locus_tag="K6K39_RS31290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EASAB2608_06400"
                     /product="amino acid ABC transporter permease"
                     /protein_id="WP_059246529.1"
                     /transl_table=11
                     /translation="MSEPPGAAVSLAEAPPPPTDRTPSKPLAAQRVQPLRRPGRWIVTA
                     VVLVLVAQILHGLVTNPFYQWDRFRYWFLRPAVLDGLLVTLEVAALSAVLGLLGGILLA
                     LARLSGSPVLRAVSWTYTWLFRSVPLIVVLIFLYNFSALYKTLSLGVPFGPAFVTFDES
                     RLATDMAIAVIGLSLNEAAYAAEVVRGGILSVDQGQHEAAAALGLPKGYQFRRIVFPQA
                     LRSITPNYVNQLIGLVKSTSLVFYVSLLDLFGAVQSMSSTYPGDVVPLLLVATVWYLIL
                     TSAVSVVQFYVERYYARGATRTLPPTPVQRARAGLAGLRDRLRREAAV"
     gene            10748..11551
                     /locus_tag="K6K39_RS31295"
                     /old_locus_tag="EASAB2608_06401"
     CDS             10748..11551
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018536144.1"
                     /locus_tag="K6K39_RS31295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EASAB2608_06401"
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="WP_221335168.1"
                     /transl_table=11
                     /translation="MSTAHTREQTLEKPAPAALEVHGVHKWYGAHRVLDGIDLTVRPGE
                     VTVILGPSGSGKSTLLRVINHLEKPEIGHVSVGGELIGVKRHGDRLKELSERTILAQRS
                     RIGFVFQSFNLFPHLTVLDNVAAAPVATGRLTRAAAAELARELLDRVGLGDKAGAYPRQ
                     LSGGQQQRVAIARALALRPGIILFDEPTSALDPELVGEVLAVIKDLATSGTTLVIVTHE
                     IGFAREVADRVVFIDGGRIVEEGPPGQVLDRPRHERTRDFLAKVL"
     gene            11809..12828
                     /locus_tag="K6K39_RS31300"
                     /old_locus_tag="EASAB2608_06402"
     CDS             11809..12828
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1091: glutamine-binding lipoprotein glnH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014676299.1"
                     /locus_tag="K6K39_RS31300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EASAB2608_06402"
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="WP_221335169.1"
                     /transl_table=11
                     /translation="MPSQFSRRALIRGLTAATVTFSLAGGLTACGGDSEAAATTDTAGT
                     VTVGRLSNGAAEETALKVSEVKSISARLPASVRKSGKLVIGVGALPSGSAPLNFVGSDQ
                     KTLTGSEPDLGRLVAAVLGLEPEIRNSTWENLFVGIDSGKVDVAFSNVTVTEERKKKYE
                     FASYRKDDVAFEVLKKNTWNFDGDYENLAGKTVSVGSGTNQEKILLEWKAKLAKEGKEL
                     TVKYFPDQNAVNLALNSGKIDAYFGPSPTVAYRARQTANSPDPTRNAGSFSGAGATLQG
                     LIAATAKKDSGLAEPVAEAINHLIENGQYGKWLAAYGLSEESVTKSRVNPPGLPLDNA"
ORIGIN
        1 tcccggtggc cgtgccgttc ctgtgccttc agcccctggt ggagaacgcg gtcaagcacg
       61 ggctggagga gagcgtcgag cgcagccgta tcggcatcac cgcacaggac gagggggcga
      121 cggcccgcat cgtcatcgag gacaacggca tcggcatgga gccggaccgg ctccgccggc
      181 tgctgcgcgg cgagggcggc cccgcgacgg gcatcgggct gcgcaacgtg gacgagcggc
      241 tgcgccaggt ctacggcgac gaccacggac tggtgatcga gaccggcgtc ggagccggca
      301 tgaagatcac catccgcatc cccaagtacc ggcccggagt gcacagcacg ccccggcacc
      361 cggggaccgg gggcgggtga gcggcgggcg gggggccgtg cgcggccacc ggcggcggac
      421 ctggcgctcg gcggtgatcg gtgcggacgc gcgttcgtcg tcaggcccgt cgcccgggcg
      481 gcggtgtccg cgggatccgg aaggatcgct tcgccgcgcg cccggcaagg ggcaccggtc
      541 tacggcacct cgaccgcctg tgtctgcttc cgctgccgac gggccgccag caccgcgtac
      601 acgatgaccc cgacgaacag gaacagcaca ccctggtaca ccgccgcgta gcccgcgccc
      661 gccatcagcc agatcgagaa ggcggcggcc accgcggtga tcacggagtc ccgcaccagc
      721 cgcgcccggt cgaccgcccg gccggacacc aggtggtaga tctgcgcggc ggtggccagc
      781 aggtacggca cggtcgcggt gaacgtggtg accagcacca ggatctcgaa gaccttgccc
      841 gagccggaca ggtagttgta gacggtgagc agcgaggcca ggacgaccgt caccccgacg
      901 ccgaccgtgg gcacgccccg ccgccggcgc gtgaaggcgc tcgggaacag cccgtcgcgg
      961 gccgccgcgt acggcgtctg ggcgctgagc agggtccagc cgttgaggca gccggtcatc
     1021 gacaccaggg cggcgagcgc caccgccgta ccgccccagc tgccgccgaa catggtgttc
     1081 acggcgtccg agaacggcgc ggtggagtcg accaggcggt cgtgcgggac cgtgccgaac
     1141 acggacagcg tgcccagcag gtacaccagc gcggcacccg cggtgccgat cacggtggcg
     1201 cgccccacgt tgcggcgggc gtccctgacc tcgcccgcgc tgacggcggc ggactccacc
     1261 ccgaggtagg agaagagcag cagcgcggcg gcggcggaca ccgcgccgat cgggctctgg
     1321 tcgccggcgt tgaacgggcc gagccggtcg gggtcgaaga agaacagtcc gccgaccgcg
     1381 acgagcagca gcggcacgaa cttcagcacc gtggacacca gctgcacggc gcccacgtac
     1441 cgggtgccgg cgaagttggc gagggccggc agccactgca gggccagcgc ggccaggcag
     1501 gcggtccagc ggtggtcgtt gaccgggatc aggacgtcca ggtatccgac ggccgcgacg
     1561 gccagcgccg cgttcgacac ccaggtggtg atccagtacg accaggcggc gaggaatccc
     1621 gcgaagtcgc cgaacgcctc gcgggcgtag acgtagggac cgccggtgcg cgggtcgcgc
     1681 gcggcgagcc ggccgaagac cagggcgagc gcgatggcgc cgacggtgag cacaccgaag
     1741 gcgaccaggc tgaccgtgcc gtacggagcg atggaggcgg ggagcaggaa gatgccgccg
     1801 ccgatgatgt tgcccatgac cagcgcggtg gcgacgggca ggccgaaccg gcgggcatgc
     1861 ctgccgttgt tgccgtgcgg gtcctcggca agggccgtgg gggactccgc ggggctgccc
     1921 gcgggggccg gagccgactg cgggacggtt ccggtgctgt gcatgggtgg tgcgcctctc
     1981 atggaactga cgttcccggg atcaccggga cgggccccat ggtcggggat gcgcggacct
     2041 ggctcaaaac cgccgttcgt tgttctgtgc gggccgcctg atcacggaaa aagcgtcgtg
     2101 gtacggccct cgcgccgcga gatgtgcggt gccccggatg cgggcactcc ggccgggggc
     2161 ggtcagtccg gcgccgccca gaggctgcgg acatgcccca gatgccgggt catgaccgcg
     2221 tgcacggcct tctcgtcccg ctccagcagg gcgtccagca gctccaggtg ctcctcggcg
     2281 gaggcgagca gccggcccgc ctccaccagc gcggtcaggc cgtacagacg ggagcgtttg
     2341 cgcaggtcgg cgacgacctc caccaggtgg gcgttgccgg ccagagcgag cagccccagg
     2401 tggaagcggg tgtcggcctc cacgtaggcg atcagatcgc ccgccaccgc cgcggtgacg
     2461 atctcccggg ccgccgggcg cagcgcctcc agcgagaccc ggtcggccgt gcgggccagc
     2521 tccaccacgg tcgggatctc gatgagcgcc cggatgtgcg tgtactcgtc cagctgctgg
     2581 tcggagacga cggtgacccg gaagcccttg ttgggcacgg tgtcgaccag cccctccttg
     2641 gccaggtcga gcatcgcctc ccgcaccggc gtggccgaga cgccgaaccg ggcggccagc
     2701 gagggcgccg agtagacctc gcccggccgc agctcgcccg cgatcagggc ggcgcgcagg
     2761 gcgtccgcga cccgctcgcg gtagctgctc cgccggccgc ccagccgggg cagtgcgggc
     2821 atctccgcgc cccgcgtgtt ctgtgccatg tcacgcatca ccggggtgag tctagaggac
     2881 gctagaggac gaaaccccgg gggaacggat cggtcgggtc cagcaggtac tgcgcggtgc
     2941 ccgtgatcca cgcgcggccg gtgaagctgg gcagcacggc cggcgccccg gcgacctccg
     3001 tcgtccccag cagccggccg gtgaaccggg tgccgatgaa ggactcgttc acgaactcgg
     3061 tgtgcagcgg gagttcaccg cgcgcgtgca gttgcgccat gcgcgcgctg gtgcccgtgc
     3121 cgcaggggga gcggtcgaac cagcccggat ggatgaccat ggcgtgccgg gagtgccggg
     3181 ccgtggcccc gggcgcgtac aggtggacgt ggtggcagcc gcggatggtc ggatcctcgg
     3241 ggtgcaccgg ttccgcctgc tcgttgatcg cctccatcag ggacagtccg gcggccagga
     3301 tgtcgtcctt gcgggcgcgg tcgaagggca gcccgagggc gtcgagcggc aggatcgcgt
     3361 agaagttgcc gccgtaggcc aggtcgtagc cgaccgtacg cccgtcgggc agggtgacct
     3421 cgcggtccag gccggccgcg aacgagggca cgttccgcag ggtcaccgca cgggcggcgc
     3481 cgtccgccac cgccacctcg gcgaccacga cgcccgccgg ggtgtcgagc cgtacggtgg
     3541 tcaccggttc cgtgaccgcc accatgccgg tctcgaccag cacggtggcc accccgatcg
     3601 tgccgtgccc gcacatcggc agatagccgg agacctcgat gtagaccacg ccccagtcgc
     3661 agtcggggcg ggtgggcggc tggaggatcg cgccgctcat ggccgagtgg ccgcgcggct
     3721 cgttcatcag cagctgcttg acgtcgtcgc ggtgttcccg gaaccacagc cgccgttcgt
     3781 tcatggtcgc cccggggatg gtgccgatcc cgccggtgat cacccgggtc ggcatgccct
     3841 cggtgtgcga gtcgacggcg tgcaggacga gtgtgctgcg catggtcggg ctccctcacg
     3901 ccaggcccgc ggcgacggcc ttctcggtgg ccgcgcggac cgcggcctcc tgctcgggcg
     3961 gcagctggac ccgcggcggg cgcaccgggc cgccgtaccg tccgacgacg tccatggaga
     4021 gcttgatcgc ctggacgaac tccacccgtg agtcccagcg cagcagcggg tgcagctgcc
     4081 ggtacagcgg gagggcggtg gtgaggtcgc cggccagcgc ggcccggtac agctccgccg
     4141 aggcgcgcgg gagcgcgttc gggtagccgg ccacccagcc cttggcgccg gccaccgcca
     4201 gctccagcag cacgtcgtcg gcaccgatca acaggtcgag ttccggggcg agttcggcga
     4261 tgcggtaggc gcggcggacg tcaccggaga actccttgac ggcgtgcacg agcccctcgc
     4321 cgtgcagccg ggccaggagt tcgggcacca ggtcgacctt ggtgtcgatc gggttgttgt
     4381 acgccaccac cggcaggccc gccttcgcga cctccgcgaa gtgggcgagc accgaccgct
     4441 cgtcggcgcg gtaggcgttg ggcggcagca gcatcaccga cgtgcagccg gcctcgcccg
     4501 cctgctcggc ccagcgccgg gcctcggccg agccgtacgc ggagacgccc ggcatcaccc
     4561 gttccccgcc gatcgcggcc acggcggtct ccaccacccg ggcccgctcc tcgggggtga
     4621 gcacctggta ctccccgagc gagccgttcg gtacgacgcc gtcgcagccg ttcgcgacga
     4681 gccaggcgca gtgctcggcg tagcggtcgt ggtcgaccga gagatcctcg cgcagcggga
     4741 gggcggtggc gacgaggatg ccgcgccagg gacggtgctg tgcctcggac atgggtgatc
     4801 tcccgtttca atagggtgtg acatatcact gggggcttgc gtggagcggg tcgagcgtgg
     4861 agccggggga gcgtcggacg gggtcgagtg tcggacgggg tggagcgtcc ggcgggtcga
     4921 gtgcggaacg ggggtgaggg cggaaccggg gcgagtgcgg aggcgggggc gtgcggcggc
     4981 gggggagtgc ggcgcggatg tcagtccgtg tcgggcaggg cggccaggac gccgagcggg
     5041 accggccggg cgaacggccg gcgtcccgcg gtgagcgggc agccggccag gccggccacc
     5101 gcgggcgcgc agacccggcc ctggcaccag cccatcccgg cccggctgag cagcttcacg
     5161 ctgcgcaggt cgggggcgcc gagcaggccg gcggactcgc gcacccgccc ggcggtgacc
     5221 tcttcgcagc ggcacaccac cgtgtcgtcc gggacccggt ccgcccagcc cgccggtggg
     5281 gcgtacaccg cctccagggc cgcggcgaag tcccgcagcc gggtcctggt ccgggcggcg
     5341 gcggcccagc ggcgcgggtc gggggcggtg ccgtgcagcc gggcggcggc cgagcgcccg
     5401 gcgatgtgcc cctcggcgag cgcgagcgcc gccccgccga caccggtggc ctccccggcg
     5461 gcccagacgc cgggcacgtc ggtgcgctgc tcggcgtcga cccgtacggc ggtgcctgac
     5521 agggtgcagc cgagggtctc ggcgaggtcg gtgtgcggga gcatgccgtg gccgacggcg
     5581 agggtgtcgc aggggatgcg ccgggcgctg ccgggccgga ggcgtccgtc ccggtcgagc
     5641 gcggccaccg tcaccgcctc cagccggtcg gtgccgtgcg ccgcgacgac ggtgtgccgg
     5701 gtcagggtgc gcacgccgtg ccgcagcagc cgggccgcgt atccggcgcc ctcggcgagc
     5761 ttgccgggct gcgcggccag ggcgggcgcc cggcgcagca gcgcggccgg accggcggac
     5821 tcgaccagcg cggcgacgcg ggcgccggcc gcggcgagcc cggtggccac cggcagcagc
     5881 agcggcccgg tcccggccac caccaccgtc cggccgggca gcaccaggcc gcccttgagc
     5941 atggcctgcg cgccgcccgc cgtgacgacc ccgggcagcg tccagcccgg gaagggcagt
     6001 acccgctcgt acccgccggt ggcgagcagg acggcgtcgg cgcggacggt gacgccctcc
     6061 tcctgtgcgg ggccgagcag agcgtgcacg ctgatcggtc cggaggccga ctcccgccgc
     6121 acgcaccaca cgtgatggtc cgtcagatgg gtgatccggc cggccgtgcg gtgccgggcc
     6181 agcccgtccc gcagccgttc ccaggtgcgc cactggtggt gcagcgcctg cggccggcgt
     6241 gccccgaggg ccgcggcggg ctgccggtag aactgcccgc cggcctgctc ggccgcgtcg
     6301 accagggtca cccggacacc ccgtgcggct gccgccagcg ccccggcgag gccggccggg
     6361 cccgcgccga tcacggcgag tcgtggtggt tcagtcatcg tcccggcccg tcccctcctg
     6421 tgtgcggatc acatctcccg ggcgcaccgg taccagacaa gcccgttggt tcgggcggcc
     6481 gttgacggtc accagacagt cgaagcacac cccgataccg cagaacaccc cgcggggccg
     6541 gccggtgccg cgcgtgctgc gccaggcggt cgtgcccgcc gcccacagcg ccgccgcgac
     6601 cgtctggccc ggcagggccg gcagcgggcg gccgtcgaag gtgacggtgc agggctcgcc
     6661 cggccgggcc cgggcccact ccagcggatt caccggacgt cgcctccctc ggtgtcgaac
     6721 cgctccggcc ggaacggcgt gagatccagc tccggcgcct ttccggtgag cgcgtgcgcg
     6781 atcaactgcc cggtgccggg ggcgagtccg atgccggcgc cctcgtgccc gcaggcgtgg
     6841 aacaggccgg gcgcccgcgg atcgggaccg atcgccggca ggtggtcggg caggtacggc
     6901 cggaagcccg cgtacgtccg cagtgcgcgg acccgctcca ggaacgggaa cagcccgatg
     6961 gccccggccg cgagggcccg gaccgcggtc agcgacagcg agcggtcgaa gcccacccgt
     7021 tcccgggtgg cgccgatcag caccggtccc gcggccgtgc cctccacgac cggcgagctg
     7081 cgcagggcgg ccgagtcgct ggccacgtcg gccacgtagt ccgcggcgta caccttgtgc
     7141 cggaccatcc gcggcagcgg ctcggtgacc agcacgaagc cgcgccgtgg cagcaccggc
     7201 agccggacgc cggcgagtgc cgcgaggtcg ccgccccagg tgcccgccgc attcaccacg
     7261 gccggtgcgt ggatctcgcc ccggtcggtg cggacgccgt acaccgtgcc gtccgccgtg
     7321 cgcagcaccc cggtcacggt ccggccgccg tgcagcgcgg caccggaggc gcgcgccagg
     7381 cgggcggcgg ccagggcggg catgacctgg gcgtcctggg ggtagtgcac accgccggcc
     7441 atgcccggcg ccatgtgcgg ttccagctcg ccgagtcggt cgccgccgac cggtacggcg
     7501 gtgacaccgg cgcgccgctg gcccgccacg aagtcctcca gcgcggcgag cgtccggggg
     7561 gtcgaggcga ccacgaggcc gcccttgggc tcgtactcga tcgcggtgcc gtgttcctgt
     7621 gccagctcgg cccacaaccg cgcggagagc agggcgagtt cgagttccgg gcccggttcc
     7681 ttgtcggaga cgagcaggtt gccctcgccg gcgccggtgg tgccgccgga caccgggccc
     7741 cggtccacca gccgtacgtc gagtccggcg cgcgcggcgt accacgcaca ggccgcgccc
     7801 accatcccgg ccccgacgac cacgacatcg caggtcagtc gcttcgtcac gccagtacta
     7861 tgtcacatgt tcctctccct gaggagaccc cgactcccag gcgtggacgc ccccttgacg
     7921 ccgtgccaag ccggatcgac actccaggga gggggaatcc tagtgaacag gtagggaacc
     7981 atgacgcgcc tcgcaccgcg caccggccgc acgggccgga cgccgctgcg cgcccctctg
     8041 ctcacctccc gccgccacat cgacctgcag cgcgtctgca gcgcgatcag ccgccaccgc
     8101 tgacccgggg cccctcggcc accgccggcc ggcccggccc gcggcggcgc gcccgtccgc
     8161 acgcccgcga tccggacgca cgtgccccgc acccatggtc cgcgcacccg caccccgcac
     8221 gcccgcaccc gcacatccgc gagcggcagg accgcacgcc gtacgcccgc acaccgcagg
     8281 gccgcacatg acaggcccgc actccgcacg cccaccaccc ggggagacgc atgtccatca
     8341 cttcgctcgc cgccgtcccg tccgcccacc gcaccgcccc cgtcttccgg ggccggatcg
     8401 gcagcgacgc gcgcagcggt cactacgccg tgccgcaccg ctaccggctc catctgtcca
     8461 ccgcctgccc cgacgggttg cgcctcgccg tcggccacag cctgctcggc ctcgacaccc
     8521 ggtgtccggt caccctcctg cccgccgtcc cggacggtcc cggaggcggc cacgcggcac
     8581 tgcgcccgct gtacgaggcg agcgcccacc gctacaccgg cccggcgctc gcgcccgtcc
     8641 tcagcgacga ctggtccgga cgcatcgtca gcacccacac cccggacatc ctgcgcgacc
     8701 tggaccggtt ccggccgggc ggcgacgccc gcctgtaccc ctccgggctt gagtccgtga
     8761 tcgaggccgt ggagcgcatg tgcggcgagg gcgtggagga ggccgcgcag cgcgccggac
     8821 gggccggcgc cgaccccgcc gagcgggccg ccgccctcga catactgctg gacaccctgg
     8881 gccggctgga gcggcggctg agcggcgagg agtacctggc cgacggccgg ctcaccgccg
     8941 ccgacatcga gctgtgggtg accctggtgc agctcgacac cgtgcaccgc tgccatctcg
     9001 acgcctccgc cgtgcaccgc atcgccggcc accgcgccct gtgggcctac gcccgccggc
     9061 tggcggccca ccccgcgttc ggccgccacc tcgacctcga cgccatcgcc cgccgccacc
     9121 acggccgctg ccagggcctg gaggccgccg gagccgccgt ccagatcctg gactgggcga
     9181 gccatgcagc ggacgcctcc gacgcttccc gcaggtgaga gcaggccgcc gacgtccaag
     9241 gaacggacgc ccgttgacat tcgaacgggc aactgcctta cttacggctc agaacggtca
     9301 tgagcgtcag cgccaagccc tggctcgctg accggcaacc ctcgcagcgc ggtggggtgc
     9361 cccaggtgac gaccggaccg gatgacgttt cggtaagcgc gaggccccac ggggccggaa
     9421 cagtgacagg tgacgccatg gacgcagctc cccggacggc cgcgagccgc ccccagggct
     9481 gcgtaccgtc gtacgccggt ctcctcgtcg ccgaccgggc cgtcgatctg ctccgcgtga
     9541 acagcgcact gtgtaccgca ccgggctctg cccgccgtca gggctgacgt ctccgcccag
     9601 ccccgcgttc ccgccgcaca ccgtccccgg cggtgtgccg ctgtccgccc agcccccggt
     9661 cccgtgcctg cccgcgcgcc gccccgtgcc gtagtgccgt cgcggcccgc acccgctcgt
     9721 gcgcggtgcc gccggggtgt ccgactccgc cggagcctgc catgagtgaa cccccgggcg
     9781 ccgccgtctc gctggccgag gcgccgccgc caccgaccga ccgcacaccg tcgaagcccc
     9841 tcgccgccca gcgggttcag ccgctgcgcc ggcccggccg gtggatcgtc accgccgtcg
     9901 tcctcgtgct cgtcgcgcag atcctgcacg gactggtcac gaaccccttc taccaatggg
     9961 accgcttccg ctactggttc ctgcgccccg ccgtcctcga cggcctcctc gtcaccctcg
    10021 aagtcgccgc gctcagcgcc gtactgggac tcctcggcgg gatcctgctg gccctcgccc
    10081 ggctctccgg cagcccggtg ctgcgcgcgg tcagctggac ctacacctgg ctgttccgct
    10141 ccgtaccgct gatcgtggtg ctgatcttcc tctacaactt cagtgccctg tacaagacgt
    10201 tgagcctcgg cgtgcccttc ggccccgcct tcgtcacctt cgacgagtcc cggctggcca
    10261 ccgacatggc gatcgcggtc atcggtctca gtctcaacga ggcggcgtac gcggccgagg
    10321 tggtccgcgg cggcatcctc tccgtcgacc aggggcagca cgaggcggct gccgcgctcg
    10381 gcctgcccaa gggctaccag ttccgcagga tcgtcttccc gcaggccctc cggtccatca
    10441 ccccgaacta cgtcaaccag ctgatcggcc tcgtcaagag cacgtccctg gtgttctacg
    10501 tgtccctgct cgacctgttc ggcgccgtgc agtcgatgag cagcacctac cccggtgacg
    10561 tcgtgccgct gctcctggtc gccaccgtct ggtacctgat cctcaccagc gccgtgtccg
    10621 tcgtccagtt ctacgtcgag cggtactacg cccggggcgc cacgcgcacc ctgccgccga
    10681 cccccgtcca gcgggcccgg gccggcctgg ccgggctgcg ggaccggctg cgcagggagg
    10741 ccgccgtatg agcaccgcac acacccgcga acagaccctg gagaagcccg ccccggccgc
    10801 cctcgaagtg cacggcgtcc acaagtggta cggcgcccac cgcgtgctcg acggcatcga
    10861 tctgaccgtc cgccccggcg aggtcacggt gatcctcgga ccgtccggtt ccggcaagtc
    10921 gacgctgctc agggtcatca accacctgga gaagccggag atcggccatg tcagcgtcgg
    10981 cggcgagctg atcggggtga agcggcacgg ggaccggctg aaggaactca gcgagcgcac
    11041 catcctggcc cagcgcagcc ggatcggctt cgtcttccag agcttcaacc tcttcccgca
    11101 cctgaccgtc ctcgacaacg tcgccgcagc ccccgtcgcc accggcaggc tgaccagggc
    11161 ggcggccgcg gaactcgccc gcgaactcct cgaccgcgtc ggcctcggcg acaaggccgg
    11221 cgcctacccg aggcagttgt ccggcggcca gcagcagcgg gtcgccatcg cccgcgccct
    11281 cgccctgcgg cccgggatca tcctcttcga cgagccgacc tcggcgctcg accccgaact
    11341 cgtcggcgag gtgctcgccg tcatcaagga cctggcgacc agcggcacca ccctcgtcat
    11401 cgtcacccac gagatcggct tcgcccgcga ggtcgccgac cgggtcgtct tcatcgacgg
    11461 cggccggatc gtcgaagagg gcccgcccgg ccaggtactg gaccgtcccc ggcacgaacg
    11521 gacccgggac ttcctcgcca aggtgctctg accgccacgg ccggtcgccc tgtcggcacc
    11581 gcccctcggg gaaccatccg tccgcgaacc gtccgtccgt taaccgtccg tccgcgaacc
    11641 gcgcgttcgc gaaccgtccg tccgcgaacc gcgcgttcgc gaaccgtccg tctgtgaacc
    11701 gcgcgttggc gaaccgcccg cccgcccgcc gaccgcccgt ccgtgcaccg tccctccgct
    11761 gaccacccct cggcgaacca gccttccgaa cgacaaggac agacagccat gcccagccag
    11821 ttctcccgac gcgccctgat ccgcggcctc accgcggcca ccgtgacctt ctccctcgcc
    11881 ggcgggctca ccgcctgcgg cggcgacagc gaggccgccg ccacgaccga caccgcgggc
    11941 acggtgaccg tgggccggct gtccaacggg gccgccgagg agaccgcgct gaaggtctcc
    12001 gaggtgaagt ccatcagcgc ccgcctgccc gcctccgtcc gcaagagcgg caagctcgtc
    12061 atcggcgtcg gcgccctgcc ctcggggtcc gccccgctga acttcgtggg cagcgaccag
    12121 aagaccctca ccggctccga accggacctc ggccgcctgg tggccgcggt gctcggcctc
    12181 gaacccgaga tcaggaactc gacctgggag aacctcttcg tcggcatcga cagcggcaag
    12241 gtcgacgtgg ccttctccaa cgtcaccgtc accgaggaac gcaagaagaa gtacgagttc
    12301 gcctcctacc ggaaggacga cgtggccttc gaggtgctga agaagaacac ctggaacttc
    12361 gacggcgact acgagaacct cgccggcaag acggtcagcg tgggctccgg caccaaccag
    12421 gagaagatcc tgctggagtg gaaggccaag ctggccaagg agggcaagga actcaccgtc
    12481 aagtacttcc cggaccagaa cgccgtcaac ctggcgctga acagcggcaa gatcgacgcc
    12541 tacttcggcc ccagccccac ggtcgcctac cgcgcccggc agaccgcgaa ctcccccgac
    12601 cccacccgca acgcgggctc cttctccggc gccggcgcga ccctccaggg actgatcgcg
    12661 gccaccgcca agaaggacag cgggctcgcc gagccggtcg ccgaggccat caaccatctg
    12721 atcgagaacg ggcagtacgg caagtggctg gccgcctacg gcctctccga ggagtcggtg
    12781 acgaagtcca gggtcaaccc gcccggcctg ccgctggaca acgcgtgaac aaccgccacg
    12841 cactccgtcc
//
