LOCUS       NZ_AP024135            26772 bp    DNA     linear   CON 08-NOV-2024
DEFINITION  Streptomyces sp. EAS-AB2608 strain NBRC 114648 chromosome.
ACCESSION   NZ_AP024135
VERSION     NZ_AP024135.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. EAS-AB2608
  ORGANISM  Streptomyces sp. EAS-AB2608
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Kitasatosporales; Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Okubo,S., Ena,E., Okuda,A., Kozone,I., Hashimoto,J., Nishitsuji,Y.,
            Fujie,M., Satoh,N., Ikeda,H. and Shin-Ya,K.
  TITLE     Identification of functional cytochrome P450 and ferredoxin from
            Streptomyces sp. EAS-AB2608 by transcriptional analysis and their
            heterologous expression
  JOURNAL   Appl Microbiol Biotechnol 105 (10), 4177-4187 (2021)
   PUBMED   33944982
  REMARK    DOI:10.1007/s00253-021-11304-z
REFERENCE   2  (bases 1 to 9320785)
  AUTHORS   Okubo,S., Ena,E., Okuda,A., Kozone,I., Hashimoto,J., Nishitsuji,Y.,
            Fujie,M., Satoh,N., Ikeda,H. and Shinya,K.
  TITLE     Direct Submission
  JOURNAL   Submitted (28-OCT-2020) Contact:Shinya Okubo Eisai Co., Ltd.;
            Tokodai 5-1-3, Tsukuba 300-2635, Japan
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Newbler v. 2.9
            Genome Coverage                   :: 53x
            Sequencing Technology             :: Miseq; PacBio RS II
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_019703895.1-RS_2024_11_06
            Annotation Date                   :: 11/06/2024 09:16:33
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,174
            CDSs (total)                      :: 8,084
            Genes (coding)                    :: 7,890
            CDSs (with protein)               :: 7,890
            Genes (RNA)                       :: 90
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 194
            CDSs (without protein)            :: 194
            Pseudo Genes (ambiguous residues) :: 0 of 194
            Pseudo Genes (frameshifted)       :: 87 of 194
            Pseudo Genes (incomplete)         :: 132 of 194
            Pseudo Genes (internal stop)      :: 10 of 194
            Pseudo Genes (multiple problems)  :: 32 of 194
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 13:41:52
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 6957638
            Orig. end                         :: 6984410
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            AP024135.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..26772
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="26"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..26772
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..26772
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:16772](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..16772
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            complement(199..1140)
                     /locus_tag="K6K39_RS30725"
                     /old_locus_tag="EASAB2608_06289"
     CDS             complement(199..1140)
                     /GO_function="GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009339288.1"
                     /locus_tag="K6K39_RS30725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EASAB2608_06289"
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="WP_059254586.1"
                     /transl_table=11
                     /translation="MGAGHDHGHAHSHAPAPGTATAAYRGRLRIALGITLTVMVVEIVG
                     GLLADSLALIADAAHMATDAVGLGMALLAIHFANRPPSTNRTFGYARAEILAALANCLL
                     LLGVGGYVLYEAVQRFVEPAATRGGLMVVFGLVGLVANSVSLLLLMRGQKESLNVRGAF
                     LEVAADALGSVAVLISAAVILATGWQAADPVASLVIGLMIVPRTLKLLRETLDVLLEAA
                     PKGVDMAEVRAHILALDGVEDVHDLHAWTITSGMPVLSAHVVVSSEVLNAIGNEKMLHE
                     LQGCLGDHFDVEHCTFQLEPGGHAEHEVRLCH"
     misc_feature    1212..1226
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.72"
                     /tool="antismash"
     gene            complement(1336..2307)
                     /gene="galE"
                     /locus_tag="K6K39_RS30730"
                     /old_locus_tag="EASAB2608_06290"
     CDS             complement(1336..2307)
                     /EC_number="5.1.3.2"
                     /GO_function="GO:0003978 - UDP-glucose 4-epimerase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006012 - galactose metabolic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: NAD_binding_4 (66-183). E-value:
                     1.6e-11. Score: 35.7. Matches aSDomain:
                     nrpspksdomains_K6K39_RS30730_NAD_binding_4.1"
                     /codon_start=1
                     /gene="galE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010: NAD-dependent epimerase/dehydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014676194.1"
                     /locus_tag="K6K39_RS30730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EASAB2608_06290"
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="WP_059254587.1"
                     /sec_met_domain="RmlD_sub_bind (E-value: 2.1e-18, bitscore:
                     65.3, seeds: 37, tool: rule-based-clusters)"
                     /sec_met_domain="Polysacc_synt_2 (E-value: 2.9e-10,
                     bitscore: 38.6, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTWLITGGAGYIGAHVARAMAGAGESVVALDDLSAAVPARLPAEV
                     PLVHGSTLDGELLKRVFAEYGVTGVVHLAARKQVAESVAQPTRYYRENVGGLATLLDAV
                     AEAGIGRLLFSSSAAVYGNPDTDLITEDTPCAPVNPYGETKLAGEWLVRAAGRAHGIST
                     VCLRYFNVAGAAAPELADTGVFNIVPMVFDRLTRDEAPRIFGDDYPTPDGTCVRDYIHV
                     ADLADAHLAAARRLSDGDLSGDLTLNIGRGEGVSVRELISVIGEVTGDRRAPVVEARRP
                     GDAPRAVASAERAAEVLGWRARRGVREMVESAWAGWRLHHGG"
     aSDomain        complement(1759..2109)
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_K6K39_RS30730_NAD_binding_4.1"
                     /evalue="1.60E-11"
                     /label="K6K39_RS30730_NAD_binding_4.1"
                     /locus_tag="K6K39_RS30730"
                     /protein_end="183"
                     /protein_start="66"
                     /score="35.7"
                     /tool="antismash"
                     /translation="VTGVVHLAARKQVAESVAQPTRYYRENVGGLATLLDAVAEAGIGR
                     LLFSSSAAVYGNPDTDLITEDTPCAPVNPYGETKLAGEWLVRAAGRAHGISTVCLRYFN
                     VAGAAAPELADTG"
     CDS_motif       complement(2236..2304)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_K6K39_RS30730_0001"
                     /evalue="6.40E-06"
                     /label="PKSI-KR_m1"
                     /locus_tag="K6K39_RS30730"
                     /protein_end="24"
                     /protein_start="1"
                     /score="18.8"
                     /tool="antismash"
                     /translation="TWLITGGAGYIGAHVARAMAGAG"
     gene            2572..4404
                     /locus_tag="K6K39_RS30735"
                     /old_locus_tag="EASAB2608_06291"
     CDS             2572..4404
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003996269.1"
                     /locus_tag="K6K39_RS30735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EASAB2608_06291"
                     /product="DUF5941 domain-containing protein"
                     /protein_id="WP_059254588.1"
                     /transl_table=11
                     /translation="MSTAIVTGQPVPGSSLESDLRSLGFDVRVAADAAETESLLAAVPA
                     DRRVALVDARFVGHPHALRLGLTDPRFPLAAVPGAVTAQPAARQALTRAVARATSADGG
                     TAAARAAEGGAPALAVDSLADRVATALDADGGAVHRPELGSLVATVPADPQARNEARQA
                     VAAVDDEAVRLKSAVKSRDGFFTTFFISPYSRYIARWCARRGLTPNQVTTASLLTALIA
                     AGCAATGTRGGFVAAGVLLIASFVLDCTDGQLARYSLQYSTLGAWLDATFDRAKEYAYY
                     AGLALGAARGGDDVWALALGAMVLQTCRHVVDFSFNEANHDATANTSPTAALSDKLDSV
                     GWTVWVRRMIVLPIGERWAMIAVLTAATTPRITFSVLLVGCAFAATYTTAGRVLRSVTR
                     KARRTDRAAQALADLADSGPLADGLRRVLAKGLPGLAVPAVALLGGAAVVACSALAGFG
                     SPLPVAGALVYVLASALAVARPLKGPLDWLVPPFFRAAEYGTVLVLAAEADVNGALPAA
                     FGLVAAVAYHHYDTVYRIRGNAGAPPARLVRAIGGHEGRTLLVTVLAAVLTASQFKVAL
                     TVLAVAVALVVLVESIRFWVSAGAPAVHDEGEPA"
     gene            4401..5153
                     /locus_tag="K6K39_RS30740"
                     /old_locus_tag="EASAB2608_06292"
     CDS             4401..5153
                     /GO_function="GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064: glucose-1-phosphate
                     adenylyl/thymidylyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010983099.1"
                     /locus_tag="K6K39_RS30740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EASAB2608_06292"
                     /product="sugar phosphate nucleotidyltransferase"
                     /protein_id="WP_059254589.1"
                     /sec_met_domain="NTP_transf_3 (E-value: 1.6e-09, bitscore:
                     37.1, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIGLVLAAGAGRRLRPYTDSLPKALVPVGPAGIEDSITVLDLTLG
                     NFAEIGLTEVAIIVGYRKEAVYERKAALERKYGLKLTLIDNDKAEEWNNAYSLWCGRDA
                     LKDGVILANGDTVHPVSVEKTLLAARGEGKKIILALDTVKQLADEEMKVVVDPDKGMTR
                     ITKLMDPAEATGEYIGVTLIEGDAAPELADALKTVWQSDPQQFYEHGYQELVNRGFRID
                     VAPIGDVKWVEIDNHDDLARGREIACQY"
     gene            5141..6202
                     /locus_tag="K6K39_RS30745"
                     /old_locus_tag="EASAB2608_06293"
     CDS             5141..6202
                     /GO_function="GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fe-ADH"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DHQ_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1181: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007494151.1"
                     /locus_tag="K6K39_RS30745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EASAB2608_06293"
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="WP_221335142.1"
                     /sec_met_domain="Fe-ADH (E-value: 1.6e-20, bitscore: 72.1,
                     seeds: 218, tool: rule-based-clusters)"
                     /sec_met_domain="DHQ_synthase (E-value: 2.7e-06, bitscore:
                     25.6, seeds: 76, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPVLTRLIPSPVVVDIRPGALDDLACVLADERISQSGRLAIAVSG
                     GSGARLRERIAPSLPGASWYEVGGGTIDDAVRLASDIKAGHYDAVVGLGGGKIIDCAKF
                     AAARVGLPLVAVATNLAHDGLCSPVATLDNDAGRGSYGVPNPIAVVIDLNVIREAPVRF
                     VRSGIGDAISNISAVADWELANRVNGEKIDGLAAAMARQAGEAVLRHPGGVGDDGFLQV
                     LAEALVLTGIAMSVSGDSRPSSGACHEINHAFDLLYPKRAAAHGEQCGLGAAFAMYLRG
                     AHEESVYMAEVLRRHGLPVTPDEIGFTVDEFVRAVEFAPETRPGRYTILEHLDIKTNQI
                     KDIYADYVKAIGS"
     gene            6180..6959
                     /locus_tag="K6K39_RS30750"
                     /old_locus_tag="EASAB2608_06294"
     CDS             6180..6959
                     /EC_number="2.7.8.-"
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_function="GO:0000287 - magnesium ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA]"
                     /GO_process="GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014049651.1"
                     /locus_tag="K6K39_RS30750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EASAB2608_06294"
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="WP_079081380.1"
                     /transl_table=11
                     /translation="MSRPSVAELRPVVHPAGVKDRRSGEHWAGRLYMREVSLRVDRYLV
                     NTRVTPNQLTYLMTVCGVLAAPALLVPGIAGAVLGVVATQLYLLLDCVDGEIARWKKQY
                     SLGGVYLDRVGAYLTDAAVLVGLGLRAADLWGTGRIDWLWAFLGTLAALGAILIKAETD
                     LVGVARHQAGKPPVQEAASELRSSGMALARRAAAALKFHRLILGIEAALLILVLAIVDQ
                     ARGDLFFTRLGTAVLAGIALLQTLLHLVSILASSRLK"
     gene            6968..7840
                     /locus_tag="K6K39_RS30755"
                     /old_locus_tag="EASAB2608_06295"
     CDS             6968..7840
                     /EC_number="2.4.-.-"
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011031159.1"
                     /locus_tag="K6K39_RS30755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EASAB2608_06295"
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="WP_059254592.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 4.1e-13,
                     bitscore: 48.4, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKVGAVIITMGNRPEELRALLDSVAKQDGDPVEVVVVGNGSPVPE
                     VPDGVRTVELPENLGIPGGRNVGIEAFGPGGQDVDILLFLDDDGLLARHDTAELCRQAF
                     AADPRLGIVSFRIADPDTGETQRRHVPRLRASDPMRSSRVTTFLGGANAVRTRVFAEVG
                     GLPDEFFYAHEETDLAWRALDAGWMIDYRADMVLYHPTTAPSRHAVYHRMVARNRVWLA
                     RRNLPALLVPVYLGVWLLLTLLRRPSRPALKAWFGGFREGWTTPCGPRRPMRWRTVWRL
                     TRLGRPPVI"
     misc_feature    complement(7890..7905)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 21.91"
                     /tool="antismash"
     gene            7930..8859
                     /locus_tag="K6K39_RS30760"
                     /old_locus_tag="EASAB2608_06296"
     CDS             7930..8859
                     /GO_component="GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003994380.1"
                     /locus_tag="K6K39_RS30760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EASAB2608_06296"
                     /product="ABC transporter permease"
                     /protein_id="WP_059254593.1"
                     /transl_table=11
                     /translation="MSETTHDGTVAVTAAPSPDEGLTAAELAAKYGLSVSGARPSLVEY
                     VRQLWGRRHFIVAFSQAKLTAQYSQAKLGQLWQVATPLLNAAVYFFIFGLILHASRGMT
                     QDVYIPFLVTGVFVFTFTQSSVMSGVRAISGNLGLVRALHFPRASLPISFSLQQLQQLL
                     FSMVVLFVVAIGFGSYPSLSWLLIVPVLALQFLFNTGLAMIMARAGAKTPDLAQLMPFV
                     MRTWMYASGVMFSIPVMLEDKPQWIATVLQWNPAAIYMDLMRFALIDGYGSENLPDHVW
                     AAAGGWAVLFAVGGFVYFWKAEERYGRG"
     gene            8852..9640
                     /locus_tag="K6K39_RS30765"
                     /old_locus_tag="EASAB2608_06297"
     CDS             8852..9640
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014676201.1"
                     /locus_tag="K6K39_RS30765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EASAB2608_06297"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_059254594.1"
                     /transl_table=11
                     /translation="MAEHTTGERRPTVIADDLHIVYRVNGAKTGKGSATAALSRILKRG
                     SDDAARGVRKVHAVRGVSFVAYRGEAIGLIGSNGSGKSTLLRAIAGLLPAEKGKVYTDG
                     QPSLLGVNAALMNDLTGERNVILGGLAMGMSREQIKERYQDIVDFSGINEKGDFITLPM
                     RTYSSGMAARLRFSIAAAKDHDVLMIDEALATGDRKFQKRSEERIRELRKEAGTVFLVS
                     HNNKSIRDTCNRVLWLERGELRMDGPTDEVLKEYEKFTGK"
     gene            10001..10897
                     /gene="hpnC"
                     /locus_tag="K6K39_RS30770"
                     /old_locus_tag="EASAB2608_06298"
     CDS             10001..10897
                     /EC_number="2.5.1.21"
                     /GO_function="GO:0004311 - farnesyltranstransferase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019985319.1"
                     /locus_tag="K6K39_RS30770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EASAB2608_06298"
                     /product="squalene synthase HpnC"
                     /protein_id="WP_059254595.1"
                     /sec_met_domain="phytoene_synt (E-value: 3.8e-39, bitscore:
                     133.4, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 6.3e-41,
                     bitscore: 139.4, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTATTEAADLERATLDKAASENFPVAPFFLPRAWRDDLMAVYGFA
                     RLVDDIGDGDLAPGGADARLLGVSAAAAEDRLVLLDAFEADLRRVFGGTPRHPLLRRLQ
                     PTVRRRGLTPEPFLGLIAANRQDQLVARYETYDDLLAYCELSANPVGRLVLAVTGTATP
                     ERIRMSDAICTALQIVEHLQDVAEDLGRDRIYLPAEDMKRFHVQEADLAVKTAGASVRA
                     LVAYEAQRARDLLNEGAPLVGSVHGRLKLLLAGFVAGGRAAIRAIAAAEYDVLPGPPRP
                     GKVQLLREAGVILRGEG"
     gene            10894..11859
                     /gene="hpnD"
                     /locus_tag="K6K39_RS30775"
                     /old_locus_tag="EASAB2608_06299"
     CDS             10894..11859
                     /EC_number="2.5.1.103"
                     /GO_function="GO:0016767 - geranylgeranyl-diphosphate
                     geranylgeranyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0016117 - carotenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnD"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003972236.1"
                     /locus_tag="K6K39_RS30775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EASAB2608_06299"
                     /product="presqualene diphosphate synthase HpnD"
                     /protein_id="WP_059254596.1"
                     /sec_met_domain="phytoene_synt (E-value: 2e-56, bitscore:
                     190.1, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 1.9e-69,
                     bitscore: 233.1, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRTVESPPHVSAPVLAAYSYCEAVTGQQARNFAYGIRLLPTAKR
                     RAMSALYAFSRRVDDIGDGDLAAEVKLARLEDTRALLARIHDGAVEEDDTDPVAVALSH
                     AARAFPIPLGGLDELIDGVQMDVRGETYETWDDLKVYCRCVAGAIGRLSLGVFGTEPGA
                     RGAERAAEYADTLGLALQLTNILRDVREDAQGGRTYLPADDLAKFGCSAGFHGPTPPEG
                     SDFAGLVHFEVRRARALFAEGYRLLPMLDRRSGACVAAMAGIYRRLLDRIERDPEAVLR
                     GRVSLPGHEKAYVAVRGLSGLDTRHVTRHVSARRTVRRRA"
     gene            12077..13492
                     /gene="hpnE"
                     /locus_tag="K6K39_RS30780"
                     /old_locus_tag="EASAB2608_06300"
     CDS             12077..13492
                     /EC_number="1.17.8.1"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018546810.1"
                     /locus_tag="K6K39_RS30780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EASAB2608_06300"
                     /product="hydroxysqualene dehydroxylase HpnE"
                     /protein_id="WP_059254597.1"
                     /sec_met_domain="DAO (E-value: 2.3e-09, bitscore: 36.2,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSQGSPPAPARGGATRSAVVVGGGLAGITAALALADAGVRVTLLE
                     GRPRLGGLAFSFQRGGLTVDNGQHVYLRCCTAYRWFLDRIEGAALAPLQDRLDVPVVDV
                     AKPEGRRLGRLRRDPLPVPLHLGRSLAAYPHLSLAERAAVGRAALALKGLDLADPALDT
                     QDFGSWLAAHGQSARAVEALWDLVGVATLNAVAGDASLGLAAMVFKTGLLSDPGAADIG
                     WARVPLGELHDRLARKALDSAGVRTEIRTRVTSVSLNENGTWSVQVPGENLETDAVVLA
                     VPQREAHALLPPGALDAPGRLLEIGTAPILNVHVIYDRKVLARPFFAALGTPVQWVFDR
                     THASGLPRGQYLALSQSAAQDEIDAPVAELRERYLPELERLIPGTRAAVVEDFFVTRER
                     TATFAPTPGVGRLRPGARTKAPGLYLAGAWTATGWPATMESAVRSGVSAADAALSALGR
                     PRPRHLFEFEEAA"
     misc_feature    12078..12096
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: weak, score: 21.1"
                     /tool="antismash"
     gene            13561..14625
                     /locus_tag="K6K39_RS30785"
                     /old_locus_tag="EASAB2608_06301"
     CDS             13561..14625
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003972234.1"
                     /locus_tag="K6K39_RS30785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EASAB2608_06301"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_059254598.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 9.1e-57, bitscore:
                     191.2, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPPASTPAPRAAVDVTALLERGRTLATPVLRAAVDRLAPPMDTVA
                     AYHFGWIDAAGNPADGDGGKAVRPALAVLSAEVTGAGPETGVPGAVAVELVHNFSLLHD
                     DLMDGDEQRRHRDTVWKVHGPAQAILVGDALFALANEVLLEPGTVEAGRATRRLTAASR
                     ALIDGQAQDISYEHRDRVSVEECLEMEGNKTGALLACASSIGAVLGGADDATADALERY
                     GYHLGLAFQAVDDLLGIWGDPEATGKQTWSDLRQRKKSLPVVAALAAGGSASERLGEIL
                     AADAKSSDFENFSEEEFAARAALIEEAGGREWTAEEARRQHTIAIEALDAVEMPDRVRD
                     SFTALADFVVVRKR"
     gene            14742..16772
                     /gene="shc"
                     /locus_tag="K6K39_RS30790"
                     /old_locus_tag="EASAB2608_06302"
     CDS             14742..16772
                     /EC_number="5.4.99.17"
                     /GO_function="GO:0016866 - intramolecular transferase
                     activity [Evidence IEA]"
                     /GO_function="GO:0051007 - squalene-hopene cyclase activity
                     [Evidence IEA]"
                     /GO_process="GO:0019746 - hopanoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="shc"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T2TS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014676206.1"
                     /locus_tag="K6K39_RS30790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EASAB2608_06302"
                     /product="squalene--hopene cyclase"
                     /protein_id="WP_059254599.1"
                     /sec_met_domain="T2TS (E-value: 3.7e-152, bitscore: 506.5,
                     seeds: 58, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTATTDGSTGATLPSRAAAASDTTLTTPEAAGVQEAAARAARRAT
                     DFLLARQDTQGWWKGDLETNVTMDAEDLLLRQFLGILDDKTTQAAAKFIRGEQREDGTW
                     ATFYGGPGELSTTIEAYVALRLAGDAPDAPHMAKASAWIRERGGIAASRVFTRIWLALF
                     GWWKWEDLPELPPELIYFPTWFPLNIYNFGCWARQTIVPLTIVSAKRPVRPAPFALDEL
                     HTDPAHPNPPQPLAPLASWDGVFQRLDKVVRGYRKVAVRRLRKAAMNSAARWIVERQEN
                     DGCWGGIQPPAVYSIIALHLLGYDLEHPVLREGLASLDRFAVWREDGARMIEACQSPVW
                     DTCLATIALVDAGLPVDHPQLVKAADWMLGEEIVRPGDWAVRRPQLPPGGWAFEFHNDN
                     YPDIDDTAEVALALRRVRHHDPERVDRAIGRAVRWNLGMQSKNGAWGAFDVDNTSPFPN
                     RLPFCDFGEVIDPPSADVTAHVVEMLAAEGLAHDPRTRRGIDWLLAEQEPDGSWFGRWG
                     VNYLYGTGSVVPALTAAGLPGSHPAIRRAVAWLERVQNDDGGWGEDLRSYQDAKEWSGR
                     GASTASQTAWALMALLAAGERGSEAVERGIRWLAETQREDGSWDEPYFTGTGFPWDFSI
                     NYHLYRQVFPLTALGRYLHGDPFERILPAKTATAASRADGS"
     gene            16774..17445
                     /locus_tag="K6K39_RS30795"
                     /old_locus_tag="EASAB2608_06303"
     CDS             16774..17445
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016431357.1"
                     /locus_tag="K6K39_RS30795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EASAB2608_06303"
                     /product="1-hydroxy-2-methyl-2-butenyl 4-diphosphate
                     reductase"
                     /protein_id="WP_059254600.1"
                     /transl_table=11
                     /translation="MSHQPAPAPLLIACALGIEHFALRTGDRGARRRGAPVRWGAGGPY
                     SVVRTGMGPKAAERSVTRHLAGPAAADTAVLATGFCAGLAPGMHPGDLVVAEETRDPRG
                     TVPCVGTELLVKELVRLLPGRTVHTGPLTGSDHVVRGPERSALLATGAIAVDMESAATL
                     LAAVRTGDRPVAAVRVVVDAPEHELVRIGTVRGGISAFRVLRSILPAFFEWHRSLLLPR
                     R"
     gene            17451..18473
                     /gene="hpnH"
                     /locus_tag="K6K39_RS30800"
                     /old_locus_tag="EASAB2608_06304"
     CDS             17451..18473
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnH"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) QueE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007386169.1"
                     /locus_tag="K6K39_RS30800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EASAB2608_06304"
                     /product="adenosyl-hopene transferase HpnH"
                     /protein_id="WP_059254601.1"
                     /sec_met_domain="PF04055 (E-value: 1.1e-17, bitscore: 63.8,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="QueE (E-value: 9.1e-09, bitscore: 34.0,
                     seeds: 32, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 6.2e-05, bitscore: 22.2,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAMPLRQSIKVATYLAEQKLRRRDKFPLIVELEPLFACNLKCEGC
                     GKIQHPAGVLKQRMPVAQAVGAVLESGAPMVSIAGGEPLMHPQIDEIVRQLVARKKYVF
                     LCTNAMLLRKKMDKFTPSPYFAFAVHIDGLRERHDESVAKEGVFDEAVEAIKEAKRRGF
                     RVTTNSTFFNTDTPQTIIEVLNFLNDDLKVDEMMISPAYAYEKAPDQEHFLGVEQTREL
                     FKKAFAGGNRRKWRLNHSPLFLDFLEGKVDFPCTAWAIPNYSLFGWQRPCYLMSDGYVP
                     TYRELIEKTDWDKYGRGKDPRCANCMAHCGYEPTAVLATMGSLKESLRAMRETVSGNRE
                     "
     gene            18478..19610
                     /gene="ispG"
                     /gene_synonym="gcpE"
                     /locus_tag="K6K39_RS30805"
                     /pseudo=""
     CDS             18478..19610
                     /GO_function="GO:0046429 - 4-hydroxy-3-methylbut-2-en-1-yl
                     diphosphate synthase activity (ferredoxin) [Evidence IEA]"
                     /GO_process="GO:0044237 - cellular metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="ispG"
                     /gene_synonym="gcpE"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011031167.1"
                     /locus_tag="K6K39_RS30805"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="flavodoxin-dependent
                     (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MTAVPLGVPEVPARPVAPRRVSRQIHVGPVAVGGGAPVSVQSMTT
                     TRTSDIGATLQQIAELTASGCQIVRVACPTQDDADALATIARKSQIPVIADIHFQPKYV
                     FAAIEAGCAAVRVNPGNIKKFDDQVKEIARAAKDHGTPIRIGVNAGSLDRACSRSTARR
                     PRRRWSSRRCGRRPSSRSTTSATSRSPSSTTTRS"
     gene            19642..21540
                     /gene="dxs"
                     /locus_tag="K6K39_RS30810"
                     /old_locus_tag="EASAB2608_06307"
     CDS             19642..21540
                     /EC_number="2.2.1.7"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0008661 - 1-deoxy-D-xylulose-5-phosphate
                     synthase activity [Evidence IEA]"
                     /GO_process="GO:0008615 - pyridoxine biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0009240 - isopentenyl diphosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="dxs"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DXP_synthase_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1110: 1-deoxy-D-xylulose-5-phosphate synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014676210.1"
                     /locus_tag="K6K39_RS30810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EASAB2608_06307"
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="WP_059254603.1"
                     /sec_met_domain="DXP_synthase_N (E-value: 9.4e-112,
                     bitscore: 371.5, seeds: 174, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.1e-05, bitscore:
                     24.1, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTILENIRGPRDLKALSEAELGELSEEIREFLVRAVSRTGGHLGP
                     NLGVVELSVALHRVFESPVDRILWDTGHQAYVHKLLTGRQDFSKLRGKGGLSGYPSREE
                     SEHDVIENSHASTALGWADGLAKANQVRGEKGHVVAVIGDGALTGGMAWEALNNIAAAR
                     DRPLIIVVNDNERSYAPTIGGLANHLATLRTTDGYEKVLAWGKDVLQRTPVVGHTLYES
                     LHGAKKGFKDAFAPQGMFEDLGLKYLGPIDGHDIKAVESALRRAKRFHGPVLVHCLTVK
                     GRGYEPALAHEEDHFHTVGVMDPLTCEPLAPSNGPSWTSVFGEEIVRIGEEREDVVAIT
                     AAMLHPVGLGKFAERFPDRVWDVGIAEQHAAVSAAGLATGGLHPVVAVYATFLNRAFDQ
                     LLMDVALHRCGVTFVLDRAGVTGTDGPSHNGMWDMSVLQVVPGLRIAAPRDADQLRAQL
                     REAVAVDDAPTLVRFPKESVGPCVPALDRVGGMDVLHRAERPEVLLVAVGVMASVCLQA
                     AELLDARGIGCTVVDPRWVKPVDPALPGLAARHRLVAVVEDNSRAAGVGSAVALALGDA
                     EMDVPVRRFGIPEQFLAHAKRSEVLADIGLTPVEIAGRISASLAVQEAGSAVKESE"
     gene            21537..22922
                     /locus_tag="K6K39_RS30815"
                     /old_locus_tag="EASAB2608_06308"
     CDS             21537..22922
                     /NRPS_PKS="Domain: Aminotran_3 (41-363). E-value: 1.6e-86.
                     Score: 282.3. Matches aSDomain:
                     nrpspksdomains_K6K39_RS30815_Aminotran_3.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1013: aminotransferase class-III"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007494124.1"
                     /locus_tag="K6K39_RS30815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EASAB2608_06308"
                     /product="aspartate aminotransferase family protein"
                     /protein_id="WP_059254604.1"
                     /sec_met_domain="Aminotran_3 (E-value: 2e-84, bitscore:
                     282.5, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTEFDLGALLAERGSERYELHAKHLNPQLPRMLHTIGFDKVYER
                     AEGAHFFDAEGNDYLDMLAGFGVMGLGRHHPVVRKALHDVLDLDLADLTRFDCQPLPGL
                     LAERLLAQSPHLDRVFFGNSGTEAVETALKFARYATGKPRVLYCDHAFHGLTTGSLSVN
                     GERGFRDGFAPLLPDTAVPLGDLDALDRELRKGDVAALIVEPIQGKGVHEAPPGYLRAA
                     QELLRGHRALLIADEVQTGLGRTGDFYAYQHEDGVEPDLVCVAKALSGGYVPVGATLGK
                     EWIFKKVYSSMDRVLVHSASFGANAQAMACGLAVLAVMENEQIVAGVRRTGELLKSRLT
                     ALIDKYEMLADVRGRGLMIGIEFGKPSSLKLRSRWTMLQAARKGLFAQMVVVPLLQRHR
                     ILTQVSGDHLEVIKLIPPLVVDEADVNRFVDAFTAVMDDAHSGGGLMWDFGKTLIKQAV
                     AHR"
     aSDomain        21660..22625
                     /aSDomain="Aminotran_3"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_K6K39_RS30815_Aminotran_3.1"
                     /evalue="1.60E-86"
                     /label="K6K39_RS30815_Aminotran_3.1"
                     /locus_tag="K6K39_RS30815"
                     /protein_end="363"
                     /protein_start="41"
                     /score="282.3"
                     /tool="antismash"
                     /translation="VYERAEGAHFFDAEGNDYLDMLAGFGVMGLGRHHPVVRKALHDVL
                     DLDLADLTRFDCQPLPGLLAERLLAQSPHLDRVFFGNSGTEAVETALKFARYATGKPRV
                     LYCDHAFHGLTTGSLSVNGERGFRDGFAPLLPDTAVPLGDLDALDRELRKGDVAALIVE
                     PIQGKGVHEAPPGYLRAAQELLRGHRALLIADEVQTGLGRTGDFYAYQHEDGVEPDLVC
                     VAKALSGGYVPVGATLGKEWIFKKVYSSMDRVLVHSASFGANAQAMACGLAVLAVMENE
                     QIVAGVRRTGELLKSRLTALIDKYEMLADVRGRGLMIGIEF"
     gene            23008..23637
                     /locus_tag="K6K39_RS30820"
                     /old_locus_tag="EASAB2608_06309"
     CDS             23008..23637
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1148: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014676212.1"
                     /locus_tag="K6K39_RS30820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EASAB2608_06309"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_059254605.1"
                     /transl_table=11
                     /translation="MNASDAAPPAAPAPDEGLPAVAPQLRSLRRRAGLTLEAAARAAGL
                     SPAHLSRLETGHRQPSLPMLLALARIYGTTVSELLGETVADRDAIVRAADMEPTRAGGW
                     TYVQAGAPGRGMQALRVRVPYGSQGDIVRVHPGEEWLYVLKGRLRLRLGDTAHLLGPGD
                     SAHFDSLTPHRLAAEDHDGVELLFVHTLLQSPTATLCLGPLTGELP"
     gene            23634..23756
                     /locus_tag="K6K39_RS30825"
                     /old_locus_tag="EASAB2608_06310"
     CDS             23634..23756
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014676213.1"
                     /locus_tag="K6K39_RS30825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EASAB2608_06310"
                     /product="DUF6126 family protein"
                     /protein_id="WP_059254606.1"
                     /transl_table=11
                     /translation="MSDFETKFPRALWIRLLIYIALGHVLAAFLYLLFAVGGKS"
     gene            23787..24587
                     /locus_tag="K6K39_RS30830"
                     /old_locus_tag="EASAB2608_06311"
     CDS             23787..24587
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010279001.1"
                     /locus_tag="K6K39_RS30830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EASAB2608_06311"
                     /product="hypothetical protein"
                     /protein_id="WP_059254607.1"
                     /transl_table=11
                     /translation="MPETSDPVAARWPLASPRTADWLRELAGDGVTGFMPPPLPDAAWV
                     LNAMYEHERGPDGVAYDAYHRARVADGSVARHIVGDLDLTEVGVATGGGLGRAGHPGPG
                     RRRLRWAELAARTGDPVVPEGLLPSFRCFPSAKQGGSWPLRITPPTEGSLDRESWHRLI
                     EVLTAHSPAGPDTPCLAYYSPLMLRNPDFENPHVRAGRLGDAGDLYDNPEVEFSPSNLW
                     AEDRSWVLCTDYDLWATKVAGPVPLVEALLADPEIEAVRLPWAP"
     gene            complement(24628..25425)
                     /locus_tag="K6K39_RS30835"
                     /old_locus_tag="EASAB2608_06312"
     CDS             complement(24628..25425)
                     /EC_number="3.1.3.48"
                     /GO_function="GO:0004721 - phosphoprotein phosphatase
                     activity [Evidence IEA]"
                     /GO_function="GO:0004725 - protein tyrosine phosphatase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019069689.1"
                     /locus_tag="K6K39_RS30835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EASAB2608_06312"
                     /product="tyrosine-protein phosphatase"
                     /protein_id="WP_059254608.1"
                     /transl_table=11
                     /translation="MTQQVPSTEPELAGVRNFRDVGGLPTVDGRRVRHGVLFRSGHLAH
                     ATEEDAAFLASLGLHTIFDFRNAADQKLEGPDVELPGVRNVNLPLSDPADGAEFWKMVR
                     DGDLDQLRAILDDGKGAARMIDSYRKIVTERTAEHSRVLHALAEDSVPALMHCAAGKDR
                     AGISIAVTLLAVGVERDAIVADYLESNAKHRRYKVRRSGSADTAYTPEVMALLDPLFDA
                     RAEYLAAAFASIEETWGDTDTYLAQGLGLSPDSRERLRARLLD"
     misc_feature    25677..25691
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.44"
                     /tool="antismash"
ORIGIN
        1 catccttcgc ctcggtcttc gcaccccaag tctgccgtac gaatccggca ctcccggcac
       61 gtcgcgcatg tccgcgcgcg gcgcggcagc gggagccgga cccggtagat catcgtgccc
      121 ggcgccggtc gccgggaacc gcccgggggt gcgccgaacg gcagtgcgta cggggtgagg
      181 cgtacggcgt cgggcgggtc agtggcacag ccggacttcg tgctccgcgt ggccgcccgg
      241 ctccagctgg aaggtgcagt gctccacgtc gaagtggtcg cccaggcagc cctgcaactc
      301 gtgcagcatc ttctcgttgc ctatggcgtt cagcacttcg gagctgacca cgacgtgcgc
      361 cgagagcacc ggcatgcccg aggtgatcgt ccaggcgtgc aggtcgtgta cgtcctcgac
      421 gccgtccagc gccaggatgt gcgcccggac ctccgccatg tcgaccccct tgggcgccgc
      481 ctccagcagc acgtccagcg tctcgcgcag cagcttcagt gtccgcggca cgatcatcag
      541 cccgatgacc agcgaggcga ccgggtccgc cgcctgccag ccggtggcca ggatcaccgc
      601 ggccgagatc agcaccgcca ccgatcccag cgcgtccgcg gccacctcca ggaaggcgcc
      661 gcgcacgttc aggctctcct tctggccgcg catcagcagg agcagcgaga cggagttcgc
      721 gaccaggcct acgaggccga acacgaccat caggccgccc cgggtcgccg cgggctccac
      781 gaaccgctgg accgcctcgt acaggacgta cccgccgacc ccgagcagca gcagacagtt
      841 ggccagggcc gcgaggatct cggcgcgggc gtagccgaag gtgcggttgg tgctcggcgg
      901 gcggttcgcg aagtggatcg cgagcagcgc cataccgagg cccaccgcgt cggtcgccat
      961 gtgggccgcg tccgcgatca gcgcgagcga gtccgcgagc aggccgccga cgatctcgac
     1021 caccatgacc gtgagcgtga tgcccagcgc gatccgcagc cgtccccggt acgcggccgt
     1081 ggccgtgccc ggggccggcg cgtgggagtg cgcgtgcccg tggtcgtgcc ctgcccccat
     1141 gactaccgcc ttccgtgtgc ctgccgggag gccagtgaac tacgggccct gggtaggggg
     1201 caacgcggca ctgaacaccg ttgtcatgtg ccctgacctg cggaaacgtt ccgcaggtca
     1261 gggggccgga gagcgtcggc cgccgggggg cggtgccgtg gcgggcgtcg gccgccgtgg
     1321 ggacgggatg cgccgtcagc cgccgtggtg cagccgccag cccgcccacg ccgactcgac
     1381 catctcccgc accccgcgcc gggcccgcca gcccagcacc tccgcggccc gctccgccga
     1441 ggccaccgcg cgcggcgcgt cgccggggcg gcgggcctcc accacgggcg cccggcggtc
     1501 gccggtgacc tccccgatga ccgagatcag ctcgcgcacc gagacgccct cgccgcggcc
     1561 gatgttcagg gtcagatcgc cgctgagatc cccgtcggag agccgccgcg ccgccgcgag
     1621 gtgggcgtcc gcgaggtcgg cgacgtggat gtagtcccgg acacaggtgc cgtccggcgt
     1681 cgggtagtcg tcgccgaaga tgcgcggggc ctcgtcccgg gtgagccggt cgaagaccat
     1741 cggcacgatg ttgaacacgc cggtgtccgc cagctccggc gccgccgcgc ccgccacgtt
     1801 gaaatagcgc aggcacaccg tggagatccc gtgcgcccgg cccgccgccc gcaccagcca
     1861 ctccccggcc agcttggtct cgccgtacgg gttcaccggg gcgcacggcg tgtcctcggt
     1921 gatcaggtcc gtgtccgggt tgccgtacac cgccgccgac gaggagaaca gcagccggcc
     1981 gatgcccgcc tccgcgaccg cgtccaggag ggtggccagg ccgccgacgt tctcccggta
     2041 gtagcgggtg ggctgcgcca ccgactccgc gacctgcttg cgcgccgcga gatggacgac
     2101 gcccgtgacg ccgtactccg cgaagacccg cttcagcagt tccccgtcca gcgtcgagcc
     2161 gtggacgagc gggacctcgg ccgggagccg cgcgggcacg gcggccgaca ggtcgtccag
     2221 cgccacgacg ctctccccgg cgccggccat ggcccgtgcc acgtgcgccc cgatgtatcc
     2281 ggctccgccg gtgatcagcc acgtcatggt cgtccaccct atgccgagtc gcccggtgtc
     2341 ctggttgccc gggtctgccc catgggtttg tggggcgggc cccggatccc cgatgatgat
     2401 cgcggcaaag gcccggacag cccccgtggg cggtgccgtg aacggccggt gaacaccgga
     2461 tccggaccat ccgatagcct ctgccgacat gccgcccggg tgccgcaggc agggcgcccc
     2521 atcatgcaca cgaccggcgc ccgcgcgccg gcacccaggg agtgagttcg gttgtcgacc
     2581 gccatcgtca ccggtcagcc ggtccccgga tcgtcactgg agagcgatct gcggtccctc
     2641 ggcttcgatg tgcgcgtggc cgccgacgcc gccgagacgg agtccctgct cgccgcggtt
     2701 cccgccgacc ggcgcgtggc cctggtcgac gcccgcttcg tcggccaccc gcacgcgctg
     2761 cgcctcggcc tgaccgaccc gcgcttcccg ctcgccgccg tgcccggcgc cgtcaccgcc
     2821 cagccggccg cccgccaggc gctcacccgg gccgtggccc gcgcgacctc cgccgacggc
     2881 ggtacggccg ccgcccgcgc ggccgagggc ggcgcccccg cgctcgccgt ggacagcctc
     2941 gccgaccgtg tcgcgaccgc cctcgacgcc gacggcggcg cggtgcaccg gccggagctg
     3001 ggcagcctgg tcgccaccgt cccggccgac ccgcaggccc gcaacgaggc ccggcaggcc
     3061 gtcgccgccg tcgacgacga ggcggtccgc ctgaagtcgg ccgtgaagtc ccgcgacggc
     3121 ttcttcacca cgttcttcat cagcccgtac tcgcggtaca tcgcccgctg gtgcgcccgg
     3181 cgcggcctga ccccgaacca ggtcaccacg gcctcgctgc tcaccgcgct catcgcggcc
     3241 ggctgcgcgg cgaccggcac ccgcggcggt ttcgtcgcgg ccggcgtgct gctgatcgcc
     3301 tccttcgtgc tggactgcac cgacggccag ctcgcccgct actccctgca gtactccacg
     3361 ctcggcgcct ggctcgacgc caccttcgac cgggccaagg agtacgccta ctacgccggc
     3421 ctcgcgctgg gagccgcgcg gggcggcgac gacgtctggg cgctggccct gggcgcgatg
     3481 gtcctccaga cctgccggca cgtggtcgac ttctccttca acgaggccaa ccacgacgcc
     3541 accgccaaca ccagtcccac ggccgccctc tccgacaagc tcgacagcgt cggctggacg
     3601 gtgtgggtgc ggcggatgat cgtcctgccc atcggcgagc gctgggcgat gatcgccgtc
     3661 ctcaccgcgg ccacgacgcc gcggatcacc ttctccgtgc tgctcgtcgg atgcgcgttc
     3721 gcggcgacgt acaccacggc ggggcgcgtg ctgcggtcgg tgacgcgcaa ggcccggcgc
     3781 accgaccggg cggcgcaggc cctcgccgac ctcgccgact cgggtccgct cgccgacggc
     3841 ctgcggcgcg tgctcgcgaa gggcctgccc gggctcgccg taccggccgt ggccctgctc
     3901 ggcggcgccg cggtcgtggc ctgctcggcg ctggccggct tcggcagccc gctcccggtg
     3961 gccggcgccc tggtgtacgt cctcgcctcg gccctcgccg tcgcccgccc cctcaagggc
     4021 ccgctcgact ggctggtccc gcccttcttc cgcgccgccg aatacggcac cgtcctggta
     4081 ctggcggccg aagcggacgt gaacggggcc cttcctgcgg ctttcgggct ggtggcggcc
     4141 gtcgcctacc atcactacga cacggtgtac cgcatccgcg gcaacgccgg agcgcccccg
     4201 gcccggctgg tgcgcgccat cggggggcac gaggggcgga cgctgctcgt caccgtcctg
     4261 gccgcggtgc tcaccgcttc gcagttcaag gtcgcgctca cggtcctcgc cgtggccgtc
     4321 gccctggtgg tgctcgtcga gagcatccgc ttctgggtgt ccgctggggc gcccgccgta
     4381 cacgacgaag gagaacccgc atgatcggcc tcgtgctggc ggccggcgcc ggacggcgtc
     4441 tgcgccccta caccgacagc ctgcccaagg cgctggtgcc ggtggggccc gcgggcatag
     4501 aggactcgat cacggtgctc gacctcacgc tcggcaactt cgccgagatc gggctgaccg
     4561 aggtcgcgat catcgtcggc taccgcaagg aggccgtgta cgagcgcaag gcggccctgg
     4621 agcggaagta cggcctgaag ctcaccctca tcgacaacga caaggccgag gagtggaaca
     4681 acgcctactc cctgtggtgc ggccgtgacg ccctcaagga cggcgtgatc ctcgccaacg
     4741 gcgacaccgt gcacccggtc tccgtcgaga agaccctgct cgccgctcgc ggcgagggca
     4801 agaagatcat cctcgcgctg gacacggtga agcagctggc cgacgaggag atgaaggtcg
     4861 tcgtcgaccc cgacaagggc atgacgagga tcaccaagct gatggacccc gccgaggcca
     4921 ccggcgagta catcggcgtc accctgatcg agggcgacgc cgcgccggag ctggccgacg
     4981 cgctgaagac ggtctggcag agcgacccgc agcagttcta cgagcacggc taccaggagc
     5041 tggtcaaccg cggcttccgt atcgacgtcg cgccgatcgg cgacgtcaag tgggtggaga
     5101 tcgacaacca cgacgatctc gcccgcggac gggagatcgc gtgccagtac tgacccggct
     5161 cattccctcg ccggtcgtcg tggacatccg cccgggtgcc ctggacgacc tggcctgcgt
     5221 cctcgccgac gaacgcatct cgcagtcggg ccggctggcc atcgccgtca gcggcggctc
     5281 cggcgcccgg ctgcgcgagc ggatcgcccc ctcgctgccc ggcgccagct ggtacgaggt
     5341 gggcggcggc accatcgacg acgcggtgcg gctggcgagc gacataaagg ccggccacta
     5401 cgacgcggtc gtcggcctcg gcggcggcaa gatcatcgac tgcgccaagt tcgcggcggc
     5461 ccgggtcggg ctgccgctgg tcgccgtcgc caccaacctc gcccacgacg gcctgtgctc
     5521 accggtcgcg accctcgaca acgacgcggg tcgcggctcg tacggcgtgc cgaacccgat
     5581 cgcggtggtc atcgacctca acgtgatccg cgaggcaccc gtccggttcg tccgctccgg
     5641 catcggcgac gccatctcca acatctccgc cgtcgcggac tgggagctgg ccaaccgggt
     5701 caacggcgag aagatcgacg gtctggccgc cgccatggcc cgccaggccg gcgaggcggt
     5761 gctccggcac cccggcggag tcggcgacga cggcttcctc caggtactgg ccgaggcgct
     5821 ggtcctcacc ggcatcgcca tgtccgtgtc gggcgactcc cgcccgtcct ccggcgcctg
     5881 ccacgagatc aaccacgcct tcgacctgct ctaccccaag cgcgccgcgg cccacggcga
     5941 gcagtgcggc ctcggcgccg ccttcgcgat gtacctgcgc ggcgcccacg aggagtcggt
     6001 gtacatggcc gaggtactgc gccggcacgg gcttccggtc accccggacg agatcggctt
     6061 cacggtggac gagttcgtcc gcgcggtgga gttcgccccc gagacccggc ccggccgcta
     6121 cacgatcctc gaacacctcg acatcaagac gaaccagatc aaggacatct acgccgacta
     6181 tgtcaaggcc atcggtagct gaactccgtc cggtcgtcca ccccgcgggg gtgaaggacc
     6241 ggcgcagcgg tgagcactgg gcgggacgcc tctacatgcg cgaggtgtcc ctgcgcgtcg
     6301 accgctacct ggtgaacacc agggtcacgc ccaaccagct cacgtacctg atgaccgtct
     6361 gcggtgtgct cgcggccccg gccctgctgg tgccggggat cgcgggcgcc gtgctcggcg
     6421 tggtcgccac ccagctgtac ctgctgctgg actgcgtcga cggcgagatc gcccgctgga
     6481 agaagcagta ctcgctgggc ggggtctacc tggaccgcgt cggcgcctac ctcaccgacg
     6541 ccgccgtgct ggtcggcctc ggcctgcgcg ccgccgacct gtggggcacc ggccggatcg
     6601 actggctgtg ggccttcctc ggcaccctcg ccgcgctcgg cgccatcctg atcaaggccg
     6661 agaccgacct ggtcggcgtc gcccggcacc aggccggcaa gcccccggtg caggaggccg
     6721 cctccgagct gcgctcctcc ggcatggcgc tggcccggcg ggccgccgcg gcgctgaagt
     6781 tccaccggct gatcctcggc atcgaggccg cgctgctcat cctggtcctc gcgatcgtcg
     6841 accaggcccg cggcgacctg ttcttcaccc gcctcggtac ggccgtcctc gcgggcatcg
     6901 ccctgctcca gacgctgctg cacctggtgt ccatcctcgc ctccagcagg ctgaagtgag
     6961 cgcgcccatg aaggtcggcg ccgtcatcat caccatgggc aaccggcccg aggagctgcg
     7021 ggccctgctc gactccgtcg ccaagcagga cggcgacccg gtcgaggtgg tcgtcgtcgg
     7081 caacggctcg cccgtcccgg aggtgcccga cggcgtccgg accgtggaac tgcccgagaa
     7141 cctgggcatc cccggcgggc gcaacgtcgg catagaggcc ttcggccccg gcggccagga
     7201 tgtcgacata ttgctcttcc tggacgacga cggcctgctc gcccgccacg acaccgccga
     7261 gctgtgccgc caggccttcg cggccgaccc gcggctcggc atcgtcagct tccgcatcgc
     7321 cgaccccgac accggcgaga cccagcgccg gcacgtgccg cggctgcgcg cctccgaccc
     7381 gatgcgctcc tcccgggtca ccaccttcct cggcggcgcc aacgccgtcc gcacccgcgt
     7441 cttcgccgag gtcggcgggc tcccggacga gttcttctac gcgcacgagg agaccgacct
     7501 cgcctggcgc gccctcgacg cgggctggat gatcgactac cgggccgaca tggtgctgta
     7561 ccacccgacg accgcgccct cgcggcacgc cgtctaccac cgcatggtcg cccgcaaccg
     7621 cgtctggctc gcccgccgca acctccccgc cctcctggtc ccggtctacc tcggcgtctg
     7681 gctgctgctc accctgctcc gccgcccctc gcggccggcc ctgaaggcct ggttcggcgg
     7741 cttccgggag ggctggacca ccccctgcgg tccccgtcgg ccgatgcggt ggcgtacggt
     7801 gtggcgactc acccgactgg gccgtccccc ggtcatctga caagctcgtc cctgagcgcc
     7861 cgtacgcccg cgccggggcc caccggacgc cgaacagaca cgcgaacccg aagacgaaag
     7921 tttccccctg tgagtgagac cacgcacgac ggcacggtcg cggtgaccgc ggccccgtcg
     7981 cccgacgagg gactgacggc ggccgagctg gccgccaagt acgggctctc cgtgagcggt
     8041 gcccggccct cgctcgtgga gtacgtccgt cagctctggg gccgccgcca cttcatcgtc
     8101 gccttctccc aggcgaagct gaccgcgcag tacagccagg ccaagctcgg ccagctgtgg
     8161 caggtggcca ccccgctgct gaacgcggcc gtgtacttct tcatcttcgg actgatcctg
     8221 cacgccagcc ggggcatgac ccaggacgtg tacatcccgt tcctggtgac cggcgtgttc
     8281 gtgttcacct tcacccagag ttcggtgatg tccggcgtcc gcgcgatctc cggcaacctc
     8341 ggcctggtgc gcgccctgca cttcccgcgc gcctcgctgc cgatctcctt ctcgctccag
     8401 cagctccagc agctgctgtt ctcgatggtc gtgctgttcg tcgtggcgat cggcttcggc
     8461 agctacccga gcctgtcctg gctgctgatc gtgccggtgc tcgcgctgca gttcctgttc
     8521 aacaccggcc tcgcgatgat catggcccgc gcgggcgcga agaccccgga cctggcccag
     8581 ctcatgccgt tcgtgatgcg cacctggatg tacgcgtccg gcgtgatgtt ctccatcccg
     8641 gtcatgctgg aggacaagcc gcagtggatc gcgacggtcc tgcagtggaa cccggcggcc
     8701 atctacatgg acctgatgcg cttcgccctg atcgacggct acggttccga gaacctgccc
     8761 gaccacgtgt gggccgcggc cggcggctgg gccgtgctct tcgccgtggg cggcttcgtg
     8821 tacttctgga aggcggagga gcggtacggc cgtggctgag cacaccaccg gggagcgtcg
     8881 ccccaccgtc atcgcggacg acctgcacat cgtctaccgg gtcaacggcg ccaagaccgg
     8941 caagggcagc gcgaccgcgg ccctgagccg gatcctcaag cggggctccg acgacgcggc
     9001 gcgcggggtg cgcaaggtgc acgccgtgcg cggcgtgtcc ttcgtcgcct accgcggcga
     9061 ggccatcggt ctgatcggct ccaacggctc cggcaagtcc accctgctgc gcgccatcgc
     9121 cgggctgctg cccgccgaga agggcaaggt ctacaccgac ggccagccgt ccctgctggg
     9181 cgtgaacgcg gccctgatga acgacctcac cggcgagcgg aacgtcatcc tcggcggcct
     9241 cgccatgggg atgtcccggg agcagatcaa ggagcgctac caggacatcg tggacttctc
     9301 gggtatcaac gagaagggcg atttcatcac cctgccgatg cgcacctact cctccggcat
     9361 ggcggcgcgc ctgcgttttt ccatcgccgc cgccaaggac cacgacgtcc tcatgatcga
     9421 cgaggcgctg gccaccggtg accggaagtt ccagaagcgc tccgaggagc ggatccggga
     9481 actgcgcaag gaggccggaa cggtctttct ggtcagtcac aacaacaagt ccatccgcga
     9541 cacctgcaac cgcgtgctgt ggctggaacg cggtgaactg cggatggacg gacccaccga
     9601 cgaggtcctg aaggagtacg agaagttcac gggcaagtga cccgtttcgg ccagggcccc
     9661 gccggaattc ctccggcggg gccctgcgtc tgcaaaggaa acgtcaactc ggcctggtct
     9721 taggaatctt ggggccaatc ggtgtgttgt tgtgatgtgc aggacacccc gacggtccgt
     9781 gccgcgttgt acaacgtaag ctgtaccggt gccggaaacc ggcaagtggg gcgataatgc
     9841 gcgacaccct gcgacggggc gcccccgcgc attgcggggc ggcgtgtccg aaatagtgtg
     9901 tattgggtcg gcagtgtaga acgggagatg tgacggcaat ggctacggaa actcccctgc
     9961 tcaccgcagc atgtgccgtc cccgttccgg gcagcgcccg atgacggcca ccaccgaggc
    10021 ggccgacctg gaacgcgcca cgctcgacaa ggccgcgagc gagaacttcc ccgtggcccc
    10081 cttcttcctg ccccgtgcct ggcgcgacga cctcatggcc gtctacggct tcgcccgcct
    10141 cgtggacgac atcggcgacg gcgacctcgc ccccggcggg gccgacgccc ggctgctcgg
    10201 cgtgtcggcc gccgcggccg aggaccggct ggtgctcctc gacgccttcg aggccgatct
    10261 gcgccgcgtc ttcggcggca ccccgcgcca tccgctgctg cgccgcctgc agcccaccgt
    10321 ccgccgccgc ggcctcaccc ccgagccgtt cctcgggctg atcgccgcca accgccagga
    10381 ccagctcgtc gcccggtacg agacctacga cgacctcctc gcctactgcg agctgtccgc
    10441 caaccccgtc ggccgcctcg tgctcgccgt caccggcacc gcgacccccg agcggatccg
    10501 gatgtccgac gcgatctgca cggcgctgca gatcgtggaa cacctccagg acgtcgccga
    10561 ggacctcggc cgcgaccgga tctacctccc cgccgaggac atgaagcgct tccacgtgca
    10621 ggaagcggac ctcgccgtga aaaccgcggg cgcatcggtg cgcgccctgg ttgcatacga
    10681 agcacaacgc gcccgcgatc tgctgaatga aggcgccccc ctggtgggta gcgtccacgg
    10741 caggctgaag ctgctgctcg cgggattcgt ggcgggggga agggcggcga tccgggcgat
    10801 cgccgccgcc gaatacgacg tacttcccgg cccgcccaga cccggcaagg tccagttgct
    10861 gcgtgaggcg ggcgtgatcc tgcgaggaga ggggtgatcc ggaccgtgga gtctccgccg
    10921 cacgtgtccg caccggtact cgccgcctac agctactgcg aggccgtcac cgggcagcag
    10981 gcccgtaact tcgcgtacgg catcaggctg ctgccgacgg ccaagcgccg cgccatgtcg
    11041 gcgctgtacg cgttctcccg gcgcgtggac gacatcggcg acggcgacct ggccgccgag
    11101 gtcaagctgg cgcgtctgga ggacacccgg gcgctgctcg cccggatcca cgacggcgcg
    11161 gtcgaggagg acgacaccga tccggtggcc gtcgccctca gccatgccgc gcgcgccttc
    11221 ccgatcccgc tcggcggcct ggacgagctg atcgacggcg tccagatgga cgtacgcggc
    11281 gagacctacg agacctggga cgacctcaag gtctactgcc ggtgtgtcgc cggtgccatc
    11341 ggccgcctct cgctcggcgt gttcggcacc gagccgggcg cgcgcggcgc cgagcgcgcc
    11401 gccgagtacg ccgacacgct gggcctcgcc ctgcagctca ccaacatcct ccgcgacgtc
    11461 cgcgaggacg cgcagggtgg ccgtacctac ctgcccgccg acgacctcgc caagttcggc
    11521 tgctcggccg ggttccacgg gccgaccccg ccggaaggct ccgacttcgc cggcctcgtc
    11581 cacttcgaag tgcggcgcgc ccgggccctg ttcgccgagg gctaccggct gctgcccatg
    11641 ctcgaccggc gcagcggcgc ctgcgtggcc gcgatggccg gcatctaccg ccggctgctg
    11701 gaccgcatcg agcgcgaccc ggaggccgtg ctgcgcggcc gggtctcgct gcccggacac
    11761 gagaaggcct acgtcgccgt gcgcggcctg tccgggctcg acacccggca cgtcacccgg
    11821 cacgtctccg cccggcgcac cgtccggagg cgcgcctgat ggacctcacc gaaccagagg
    11881 acacgcgtga ggcaaccctc caccgcggcc cggcgtccct gacggcgacg gcgccctaca
    11941 gcgccccaaa ggggcgcggg gctgtgtcgg atctgcggct accgccgcgt gagcgcgaca
    12001 agccaccacg ggcccgcaga cgaaggacgg cccaccccgg ccccgcccgc ggagcgcacg
    12061 cacggaagga cgcacgatga gccaaggctc accccccgca ccggcccgcg gcggagccac
    12121 gcgcagcgcg gtcgtggtcg gcggcggcct ggccggcatc accgcggcgc tcgccctcgc
    12181 cgacgcgggc gtccgggtca ccctgctcga aggcaggccc aggctgggcg gcctcgcctt
    12241 ctccttccag cgcggcggac tgaccgtcga caacggccag cacgtgtacc tgcgctgctg
    12301 caccgcctac cgctggttcc tcgaccggat cgagggcgcg gcgctggcgc cgctgcagga
    12361 ccgcctggac gtgcccgtcg tcgacgtcgc caagcccgag gggcggcggc tcggcaggct
    12421 gcggcgcgac ccgctgcccg tccccctcca cctggggcgc agcctggccg cctatccgca
    12481 cctctcgctc gccgagcgcg cggccgtcgg gcgggccgcg ctcgcgctga aggggctcga
    12541 cctcgccgat ccggcgctgg acacccagga cttcggcagc tggctggccg cgcacggcca
    12601 gtcggcgcgc gccgtggagg ccctgtggga cctggtcggg gtcgccaccc tcaacgcggt
    12661 cgcgggcgac gcctcgctgg ggctcgccgc gatggtgttc aagaccggtc tgctgtccga
    12721 cccgggcgcg gccgacatcg gctgggcccg cgtcccgctg ggcgaactgc acgaccggct
    12781 ggcccgcaag gcgctcgact ccgcgggcgt ccgtaccgag atccgtacac gcgtcacctc
    12841 cgtctctctc aacgagaacg ggacgtggag cgttcaggtt cccggcgaga acctggaaac
    12901 cgacgcggtc gtcctcgccg taccccagcg cgaggcccac gcgctgctgc cgcccggtgc
    12961 cctcgacgcg cccggccggc tgctggagat cggcaccgcg cccatcctca acgtccatgt
    13021 gatctacgac cgcaaggtgc tcgcgcggcc cttcttcgcc gccctcggca ccccggtgca
    13081 gtgggtgttc gaccgcaccc acgcctccgg gctgccccgc ggccagtacc tcgcgctgtc
    13141 ccagtcggcc gcgcaggacg agatcgacgc cccggtcgcc gaactccgcg agcgctacct
    13201 gcccgagttg gaacgactca ttccgggtac gcgcgcggcc gtggtggagg acttcttcgt
    13261 gacccgggag cgcacggcga cgttcgcccc cacccccggc gtcgggcgcc tcaggcccgg
    13321 cgcccgcacc aaggcccccg gcctgtacct ggccggagcg tggaccgcca ccgggtggcc
    13381 cgcgaccatg gagagtgcgg tccgcagtgg agtgagcgcg gccgacgccg cgctcagcgc
    13441 cctcggccgg ccccgccccc gtcacctctt cgaattcgag gaggcggcct gatgcccgat
    13501 cagcaggcgg cacgcccccg cacccccggt accgcaacaa gaggagagac tgtgcccact
    13561 gtgcccccgg cctcgacgcc cgctccacgg gccgcggtgg acgtgaccgc gctgctggag
    13621 cgcggccgaa ccctggccac accggtgctg cgcgcggccg tcgaccgcct ggcacctccc
    13681 atggacaccg tcgccgccta ccacttcggc tggatcgacg ccgccggcaa ccccgccgac
    13741 ggcgacggcg gcaaggccgt ccgccccgcc ctcgccgtgc tctccgccga ggtcaccggc
    13801 gccgggcccg agacgggcgt cccgggcgcg gtcgccgtcg aactcgtgca caacttctcg
    13861 ctgctgcacg acgacctcat ggacggcgac gagcagcgcc ggcaccgcga caccgtctgg
    13921 aaggtgcacg gccccgccca ggccatcctg gtcggcgacg ccctgttcgc cctcgccaac
    13981 gaggtcctgc tggagccggg cacggtcgag gccggccgcg ccacccgccg gctgaccgcc
    14041 gcctcccgcg ccctgatcga cggccaggcc caggacatct cctacgagca ccgcgaccgg
    14101 gtcagcgtcg aggagtgcct ggagatggag ggcaacaaga ccggcgccct gctcgcctgc
    14161 gcctcctcca tcggcgcggt cctcggcggc gcggacgacg ccaccgccga cgcgctggaa
    14221 cggtacggct accacctcgg cctcgccttc caggccgtgg acgacctgct cggcatctgg
    14281 ggcgacccgg aggccaccgg caagcagacc tggagcgacc tgcgccagcg caagaagtcc
    14341 ctgccggtgg tggccgcgct cgcggccggc ggatccgcct ccgagcggct cggcgagatc
    14401 ctcgccgccg acgccaagag cagcgacttc gagaacttct ccgaggagga gttcgcggcc
    14461 cgggccgctc tcatcgagga ggccggcggc cgcgagtgga cggccgagga agcgcgccgt
    14521 cagcacacca tcgccatcga agccctcgac gccgtcgaga tgcccgaccg ggtgcgggac
    14581 tccttcacgg cgctcgccga cttcgtcgtc gtacgaaaga gatgatcact attggctgga
    14641 taagcctcgc gtagtcgccg gccggtgtcg aagggttccg gacaccggcc gacggcggac
    14701 ccacagcagc acgactcgca cgactgcacg aaggggaagc catgacagcg acgaccgacg
    14761 gaagcaccgg ggcgaccttg ccgtcccgcg ctgccgcggc cagcgacacc accctcacca
    14821 cccccgaggc ggccggggta caagaagccg ccgcacgcgc cgcacggcgc gccaccgact
    14881 tcctgctcgc ccggcaggac acccagggct ggtggaaggg cgacctggag accaacgtca
    14941 ccatggacgc cgaggatctg ctgctccgcc agttcctggg catcctggac gacaagacga
    15001 cgcaggccgc cgcgaagttc atccgcggcg agcagcgcga ggacggcacc tgggccacct
    15061 tctacggcgg acccggcgaa ctgtccacca ccatcgaggc gtacgtcgcc ctgcggctgg
    15121 ccggcgacgc gcccgacgcc ccgcacatgg cgaaggcgtc cgcctggatc cgcgaacgcg
    15181 gcggcatcgc cgcctcccgg gtcttcaccc ggatctggct cgccctgttc ggctggtgga
    15241 agtgggagga cctgcccgaa ctcccgccgg agctgatcta cttccccacc tggttcccgc
    15301 tcaacatcta caacttcgga tgctgggccc ggcagaccat cgtgccgctg accatcgtct
    15361 ccgccaagcg cccggtgcgt cccgccccct tcgcgctgga cgagctgcac accgacccgg
    15421 cccaccccaa cccgccgcag ccgctcgccc cgctggcgag ctgggacggc gtcttccagc
    15481 ggctcgacaa ggtggtccgc ggctaccgca aggtcgccgt gcgcaggctc cgcaaggccg
    15541 cgatgaactc ggcggcccgc tggatcgtcg agcgccagga gaacgacggc tgctggggcg
    15601 gcatccagcc gccggccgtg tactcgatca tcgccctcca tctgctcggc tacgacctgg
    15661 agcacccggt gctgcgcgag ggcctcgcct cgctcgaccg cttcgccgtc tggcgcgagg
    15721 acggcgcgcg gatgatcgag gcctgccagt ccccggtgtg ggacacctgc ctggccacca
    15781 tcgccctcgt ggacgccggt ctgccggtcg accatccgca actggtcaag gcggccgact
    15841 ggatgctcgg cgaggagatc gtccggcccg gcgactgggc cgtgcggcgg ccccaactgc
    15901 ccccgggcgg ctgggcgttc gagttccaca acgacaacta cccggacatc gacgacaccg
    15961 ccgaggtcgc cctcgcgctg cgccgggtcc ggcaccacga cccggagcgg gtggaccggg
    16021 cgatcgggcg ggccgtccgc tggaacctcg gcatgcagtc gaagaacggc gcctggggcg
    16081 ccttcgacgt cgacaacacc agcccgttcc ccaaccggct gccgttctgc gacttcggcg
    16141 aggtcatcga cccgccgtcc gccgacgtca ccgcgcacgt cgtggagatg ctcgccgccg
    16201 agggcctggc ccacgacccg cgcacccggc gcggcatcga ctggctgctc gccgaacagg
    16261 aaccggacgg ctcgtggttc ggccgctggg gggtcaacta cctctacggc accgggtcgg
    16321 tcgtccccgc gctcaccgcg gccgggctgc ccggctcgca cccggcgatc cggcgggccg
    16381 tggcctggct ggagcgcgtc cagaacgacg acggcggctg gggcgaggac ctgcgctcct
    16441 accaggacgc caaggagtgg agcggccggg gcgcctccac cgcctcgcag acggcgtggg
    16501 cgctgatggc gctgctcgcc gcgggggaga ggggctccga ggccgtcgag cgcggcatcc
    16561 ggtggctggc cgagacccag cgggaggacg gcagctggga cgagccgtac ttcaccggca
    16621 ccggcttccc ctgggacttc tccatcaact accacctcta ccggcaggtg ttcccgctca
    16681 ccgcgctcgg ccgctacctg cacggggacc ccttcgagcg catcctgccg gccaagaccg
    16741 cgacggccgc gtcccgggcc gacgggagct gacttgagcc accagcccgc cccggccccg
    16801 ctgctgatcg cctgcgcgct cggcatcgag cacttcgccc tgcgcaccgg cgacaggggg
    16861 gcgcggcgca ggggcgcgcc ggtcaggtgg ggtgccggcg ggccgtactc cgtcgtccgt
    16921 acggggatgg gccccaaggc ggcggaacgc tccgtcaccc ggcacctcgc cggcccggcg
    16981 gcggccgaca cggccgtgct ggccaccggc ttctgcgccg ggctcgcccc cgggatgcac
    17041 cccggcgacc tggtcgtcgc cgaggagacc cgggacccgc gcgggaccgt cccgtgcgtg
    17101 ggcaccgaac tgctggtcaa ggaactcgtg cgcctgctgc ccgggcgcac ggtccacacc
    17161 ggcccgctca ccggctccga ccacgtggtc cgggggcccg agcggtccgc tctgctcgcc
    17221 accggcgcga tcgcggtcga catggagtcg gcggccacgc tgctggccgc cgtccgcacg
    17281 ggcgaccgtc cggttgcggc cgtccgggtg gtcgtggacg ctcccgaaca cgaactcgtc
    17341 cggatcggca cggtgcgcgg tggaatatct gccttccgcg ttcttcgttc catccttccc
    17401 gcatttttcg aatggcaccg ttctttgctg ctccctcgga ggtgagccag atggccatgc
    17461 cgttgcgtca gtccatcaag gtcgctacat acctggccga acagaagctc cgcaggcggg
    17521 acaagttccc gctcatcgtc gagctggaac cgttgttcgc ctgcaatctg aagtgcgagg
    17581 gctgcggcaa gatccagcac ccggccggtg tgctcaagca gcgcatgccg gtcgcccagg
    17641 cggtgggcgc ggtgctggag tccggtgcgc cgatggtctc catcgccggc ggcgaaccgt
    17701 tgatgcatcc tcagatcgac gagatcgtgc ggcagttggt ggccaggaag aagtacgtgt
    17761 tcctgtgcac caacgccatg ctgctgcgca agaagatgga caagttcacg ccctcgccct
    17821 atttcgcgtt cgccgtgcac atcgacgggc tgcgtgagcg gcacgacgag tcggttgcga
    17881 aggaaggcgt gttcgacgag gcggtggagg ccatcaagga ggccaagcgg cgcggcttcc
    17941 gggtgaccac caactccacc ttcttcaaca ccgacacccc gcagaccatc atcgaggtgc
    18001 tcaacttcct caacgacgac ctgaaggtcg acgagatgat gatctcgccc gcctacgcct
    18061 acgagaaggc gcccgaccag gagcacttcc tcggcgtcga gcagacccgg gagctgttca
    18121 agaaggcctt cgcgggcggc aaccgccgca agtggcggct caaccactcc ccgctcttcc
    18181 tggacttcct ggagggcaag gtcgacttcc cgtgcaccgc ctgggcgatc ccgaactact
    18241 ccctcttcgg ctggcagcgc ccctgctacc tgatgagcga cgggtacgtg ccgacgtacc
    18301 gcgaactcat cgagaagacc gactgggaca agtacggccg cggcaaggac ccgcgctgcg
    18361 ccaactgcat ggcgcactgc ggctacgagc cgaccgccgt cctcgccacc atgggctccc
    18421 tgaaggagtc cctgcgggcg atgcgcgaga ccgtctccgg aaaccgggag tgaggcgatg
    18481 accgccgtcc ccttgggtgt tcccgaggta ccggcccgtc cggtcgcgcc gcgccgggtg
    18541 tcgcggcaga tccacgtcgg gccggtggcg gtcgggggcg gagccccggt gtcggtgcag
    18601 tcgatgacga cgacccgtac gtcggacatc ggcgccaccc tccagcagat cgccgagctg
    18661 accgcgtccg gctgtcagat cgtccgtgtg gcctgcccca cgcaggacga cgcggacgcc
    18721 ctcgcgacca tcgcccgcaa gtcgcagatc ccggtgatcg cggacatcca cttccagccg
    18781 aagtacgtgt tcgcggccat cgaggccggc tgcgcggcgg tccgcgtgaa cccgggcaac
    18841 atcaagaagt tcgacgacca ggtcaaggag atcgcgcggg ccgccaagga ccacggcacg
    18901 ccgatccgga tcggtgtcaa cgccggctcg ctggaccgcg cctgctccag aagtacggca
    18961 aggcgacccc ggaggcgctg gtcgagtcgg cgctgtggga ggcgtccctc ttcgaggagc
    19021 acgacttccg cgacatcaag atctccgtca agcacaacga cccggtcgtg atgatcgagg
    19081 cctaccggca gctcgccgag cagtgcgact acccgctgca cctgggcgtg acggaggccg
    19141 gccccgcctt ccagggcacg atcaagtcgg ccgtcgcctt cggggcgttg ctctcgcgcg
    19201 gcatcgggga caccgtccgc gtgtcgctga gcgccccgcc ggccgaggag gtcaaggtcg
    19261 gcatccagat cctggagtcg ctgaacctcc gccagcgcgg cctggagatc gtctcctgtc
    19321 cgtcctgcgg ccgggcgcag gtggacgtgt acaagctcgc cgaggaggtc acggcgggcc
    19381 tggacggcat ggacgtaccg ctcagggtcg cggtgatggg gtgtgtggtc aacggtccgg
    19441 gcgaggcccg ggaggcggac ctcggggtgg cctcgggcaa cggcaagggc cagatcttcg
    19501 tcaagggcga ggtcgtcaag accgtccccg agtccaagat cgtcgagacc ctcatcgagg
    19561 aggccatgag gctggccgag cggaagagcc ccgcagagca agtgagttga ggcaaggcac
    19621 aaaccgagag ggggcccgag cgtgaccatt ctggagaaca tccggggacc acgcgacctg
    19681 aaggcgctgt ccgaggcgga actcggtgaa ctgtccgagg agatacgtga gttcctggtg
    19741 cgcgcggtgt cgcggaccgg cggccacctc gggcccaacc tgggcgtggt ggaactctcc
    19801 gtcgcgctcc accgcgtctt cgagtcgccg gtcgaccgga tcctgtggga caccggccac
    19861 caggcgtacg tccacaagct gctgaccggc cgtcaggact tctccaagct gcgcggcaag
    19921 ggcggcctgt ccggctatcc ctcgcgcgag gagtccgagc acgacgtcat cgagaacagc
    19981 cacgcctcca ccgcgctcgg ctgggccgac ggcctggcca aggccaacca ggtgcggggg
    20041 gagaaggggc atgtggtcgc ggtcatcggc gacggcgcgc tgaccggcgg catggcctgg
    20101 gaggcgctga acaacatcgc cgcggccagg gaccggccgc tgatcatcgt cgtcaacgac
    20161 aacgagcggt cgtacgcccc caccatcggc ggcctcgcca accacctggc caccctgcgc
    20221 accaccgacg gctacgagaa ggtgctcgcc tggggcaagg acgtgctcca gcgcaccccg
    20281 gtcgtcggcc acacgctgta cgagtccctg cacggcgcga agaagggatt caaggacgcc
    20341 ttcgccccgc agggcatgtt cgaggacctg ggcctgaagt acctcggccc gatcgacggc
    20401 cacgacatca aggccgtcga gtccgcgctg cgccgcgcga aacgcttcca cggccccgtc
    20461 ctggtccact gcctgaccgt gaagggccgc ggctacgagc ccgccctcgc gcacgaggag
    20521 gaccacttcc acaccgtcgg cgtgatggac ccgctcacct gcgagccgct cgccccgtcc
    20581 aacgggccct cctggacctc ggtgttcggc gaggagatcg tcaggatcgg cgaggagcgc
    20641 gaggacgtcg tggcgatcac cgcggcgatg ctccacccgg tcgggctcgg gaagttcgcc
    20701 gagcgcttcc cggaccgggt gtgggacgtg ggcatcgccg agcagcacgc ggccgtgtcc
    20761 gcggccggcc tcgcgaccgg cgggctgcac ccggtcgtcg ccgtctacgc caccttcctc
    20821 aaccgggcct tcgaccagct gctgatggac gtcgccctgc accgctgcgg ggtcaccttc
    20881 gtcctggacc gggccggcgt caccggcacc gacgggccct cccacaacgg catgtgggac
    20941 atgtcggtcc tccaggtcgt gcccgggctc aggatcgccg ccccgcgcga cgccgaccag
    21001 ctgcgcgcac agctgcgcga ggcggtcgcc gtggacgacg cgcccaccct ggtccgcttc
    21061 ccgaaggagt cggtcggccc gtgcgtcccg gccctcgacc gggtcggcgg catggacgtc
    21121 ctgcaccgcg ccgaacgccc cgaggtgctg ctggtggccg tcggggtgat ggcctccgtg
    21181 tgcctccagg ccgccgagct gctcgacgcc cgcggcatcg gctgcacggt ggtcgacccg
    21241 cgctgggtca agcccgtcga ccccgcgctg cccggcctcg ccgcccggca ccggctggtg
    21301 gccgtggtcg aggacaacag ccgtgcggcg ggcgtgggtt cggcggtggc gctggccctc
    21361 ggcgacgccg aaatggacgt gccggtacgg cggttcggca tccccgagca gttcctcgcg
    21421 cacgccaagc gcagcgaggt gctggccgac atcggcctca cgcccgtcga gatcgccggg
    21481 cggatcagcg cgagcctggc cgtccaggag gcgggcagcg cagtcaagga gagtgaatga
    21541 ccaccgagtt cgacctcggc gccctgctcg ccgagcgcgg atccgaacgc tacgagctgc
    21601 acgccaagca cctcaacccg cagctcccgc gcatgctgca caccatcggc ttcgacaagg
    21661 tctacgaacg tgccgagggg gcgcacttct tcgacgcgga gggcaacgac tacctggaca
    21721 tgctcgccgg gttcggggtg atgggcctgg gccgccatca cccggtcgtc cgcaaggcgc
    21781 tgcacgacgt cctggacctg gacctcgccg acctcacccg cttcgactgc cagccgctgc
    21841 ccggtctgct cgccgagcgg ctgctggccc agagccccca cctggaccgg gtgttcttcg
    21901 gcaacagcgg caccgaagcg gtcgagacgg ctttgaagtt cgcccggtac gccaccggca
    21961 agccgcgcgt cctctactgc gaccacgcct tccacggcct gaccaccggc tcgctgtcgg
    22021 tcaacggcga gcgcggcttc cgggacgggt tcgccccgct gctgcccgac accgccgtac
    22081 ccctcggcga tctcgacgcc ctggaccgcg agttgcgcaa gggcgacgtg gccgcgctga
    22141 tcgtggagcc gatccagggc aagggcgtgc acgaggcgcc gcccggctat ctgcgggccg
    22201 cgcaggaact gctgcggggg cacagggcgc tgctcatcgc cgacgaggtg cagaccggcc
    22261 tcggccgcac cggcgacttc tacgcctacc agcacgagga cggcgtcgaa ccggacctgg
    22321 tgtgcgtggc caaggccctc tccggcggct atgtgccggt cggcgccact ctcggcaagg
    22381 agtggatctt caagaaggtc tactcgtcca tggaccgtgt gctggtgcac tcggcgagct
    22441 tcggcgccaa cgcccaggcg atggcgtgcg gcctcgccgt gctggcggtc atggagaacg
    22501 agcagatcgt ggccggcgtg cgccgcacgg gcgagctgct gaagtcccgg ctcaccgcgc
    22561 tgatcgacaa gtacgagatg ctcgccgacg tccgcggccg gggcctgatg atcggcatcg
    22621 agttcggcaa gccgtcctcg ctgaagctgc gcagccgctg gaccatgctc caggcggctc
    22681 gcaagggcct gttcgcgcag atggtcgtcg taccgctgct ccagaggcac cggatcctca
    22741 cccaggtctc cggcgaccat ctggaggtga tcaagctgat tccgccgctg gtggtcgacg
    22801 aggccgacgt gaaccggttc gtggacgcct tcaccgcggt gatggacgac gcgcacagcg
    22861 gcggcggcct gatgtgggac ttcggcaaga ccctgatcaa gcaggcggtg gcacaccgct
    22921 gagtcgcggg ccggccggag cgaaggggtc ctttgcctca gaggcaagaa aattgcccgc
    22981 gaggcaagag tcgggctgaa tggaggcatg aacgcctcag acgccgcgcc gccggcggct
    23041 ccggctcccg acgagggcct gcccgccgtc gcgccgcagc tgcgctccct gcgccggcgc
    23101 gccggcctca ccctggaggc cgcggcacgc gccgccgggc tctcgccggc ccatctgtcc
    23161 cgcctggaga ccgggcaccg tcagccgtcg ctgccgatgc tcctggcgct cgcccgtatc
    23221 tacggtacga ccgtctccga actgctcggc gagacggtcg ccgaccggga cgcgatcgtg
    23281 cgggccgccg acatggaacc gacccgggcg ggcggctgga cgtacgtcca ggccggggcg
    23341 cccggccgcg gcatgcaggc cctgcgggtg cgggtgccgt acggctcgca gggcgacatc
    23401 gtgcgcgtcc accccggcga ggagtggctc tacgtcctca aggggcgcct gcggctgcgg
    23461 ctcggcgaca ccgcgcacct gctcggaccc ggtgacagcg cgcacttcga ctcgctcacc
    23521 ccgcaccgcc tcgccgccga ggaccacgac ggcgtcgagc tgctgttcgt ccacaccctg
    23581 ctgcagagcc ccacggccac gctgtgcctg gggccgctga ccggagagct gccatgagcg
    23641 acttcgagac caagttcccc cgtgccctgt ggatccggct gctcatctac atcgccctcg
    23701 ggcacgtcct ggccgccttc ctctacctgc tgttcgcggt gggcggcaag agctgacccg
    23761 ccgggccggc gtggcaggat gtgcggatgc ccgagacatc cgatccggtg gccgcgcgct
    23821 ggccgctcgc ctcgccgcgc acggccgact ggctgcgcga actggccggg gacggcgtca
    23881 ccgggttcat gccgccgccg ctgccggacg ccgcctgggt gctcaacgcc atgtacgagc
    23941 acgagcgggg tccggacggc gtggcctacg acgcgtacca ccgggcccgg gtcgcggacg
    24001 gcagcgtggc ccggcatatc gtcggggacc tcgacctcac cgaggtgggg gtcgccaccg
    24061 gcggcgggct cggccgcgcc gggcatccgg gccccggccg gcggcggttg cgctgggcgg
    24121 aactggccgc gcggaccggc gaccccgtgg tgcccgaggg actcctgccc tccttccgct
    24181 gcttcccctc ggcgaagcag ggcggcagct ggccgctgcg gatcacgccg cccaccgagg
    24241 gcagcctgga ccgcgagtcc tggcaccggc tgatcgaggt gctcaccgcg cacagcccgg
    24301 cgggcccgga caccccctgc ctggcctact acagcccgct gatgctccgg aaccccgact
    24361 tcgagaaccc gcacgtacgg gccgggcggc tcggcgacgc cggggacctc tacgacaacc
    24421 ccgaggtcga gttcagcccg tccaacctct gggccgagga ccgctcctgg gttctgtgca
    24481 ccgactacga cctgtgggcc accaaggtgg cgggccccgt cccgctcgtc gaggccctcc
    24541 tggccgaccc ggagatcgag gccgtccgcc tgccctgggc cccctgaccc gcgggccgca
    24601 cggcgttgcc ggcagcgggc tccccggtca gtcgagcagg cgcgcgcgca gccgctcgcg
    24661 ggagtcgggg gacaggccca ggccctgcgc caggtacgtg tccgtgtcgc cccaggtctc
    24721 ctcgatgctc gcgaaggccg ccgccaggta ctcggcgcgg gcgtcgaaga gcgggtcgag
    24781 cagcgccatc acctcggggg tgtacgcggt gtccgcgctg ccgctgcgcc ggaccttgta
    24841 acggcggtgc ttggcgttgg actccaggta gtcggccacg atcgcgtccc gctcgacccc
    24901 cacggccagc agggtcacgg ctatggagat gcccgcgcgg tccttgccgg ccgcacagtg
    24961 catcagcgcg ggcacgctgt cctcggcgag cgcatgcagc acccgggagt gctcggcggt
    25021 gcgctcggtg acgatcttcc ggtaggagtc gatcatccgg gccgcgccct tgccgtcgtc
    25081 caggatcgcg cgcagctggt cgaggtcgcc gtcgcggacc atcttccaga actcggcgcc
    25141 gtccgccggg tcgctcagcg gcaggttcac attccgcacg ccgggcagct cgacgtcggg
    25201 gccctccagc ttctggtcgg ccgcgttgcg gaagtcgaag atcgtgtgca ggcccaggga
    25261 ggcgaggaag gccgcgtcct cctcggtcgc gtgcgcgaga tggccgctgc ggaacagcac
    25321 tccgtggcgc acccgccgcc cgtccacggt cggcagcccg cccacatcac ggaaattgcg
    25381 cactccggcc agctccggct cggtcgacgg gacctgctgc gtcacggggg ctcctcccgg
    25441 tcggttcccg ccgtcgcggc tcgtcggcgg gcgctcagac gaccatacgg catcgattac
    25501 ctcgggcaat gagttgtcca caggcattgt cagagggtcc gcggcccctg atgatgttgg
    25561 cacttgcgcg gatctgttgg cacctgtgag gtctcgatga cggacatcgc cgaagacggc
    25621 cgtacctggc tcatgtcggg ccccagcagc agctacgccc tgcatctcac cgacgcggac
    25681 gagctgctcc atctgcactg ggggccacgg atcgccctgg ccgacgccga ggcgctcgcg
    25741 gagcgcccgc tgcccggtca ctggcccttc gagtccccgc tcgacggtcg tgaggagtac
    25801 cccgtcgagg gcgggccccg tttcgtccgt cccgccctgt ccgtccgcac cgaggaccgg
    25861 cgcggcaccg agtggcgctt cgtgtcgtac gccgccgcag gcgacgagct gcggctgcgc
    25921 ttcgacgacg acggcgtggg cgtcacgctg cactaccgga tgcgcggcga cgtcgtggag
    25981 cgctgggtga ccgtggagaa cggcggccac gcgcgcgtgg agctgctccg cgccgacgcg
    26041 gccacctgga ccctgcccga ccgcgagggc tggcggctgt cccagctgca cggccgctgg
    26101 gccgccgagt cccggctcac cagcgccccg ctcacctacg gcgagaaggt catcggcagc
    26161 cgccgcgggc acaccggcca ccagcacctg ccctgggtcg ccctggacac cgacgccacc
    26221 gaggagcgcg gcgaggtcta cggctgcgcg ctcggctggt ccggttcctg gcgcatcgcc
    26281 gtcgcccaac tcccggacgc gcgcgtgcag atcaccggcg gcgccggcta cgacgactcc
    26341 ggcctgctgc tcctcgcgcc cggggagtcg tacaccaccc cggtcttcgc gggcctgtgg
    26401 agcgacggcg gcttcggcgg cgcgagccgt gcctggcacg cctaccagcg cgcccatgtc
    26461 atcccggacg ccgagcggga ccggcccgtg ctgttcaact cctgggaggc gacgtacttc
    26521 gacatctccg aggagcagca ggccgccctc gcccgccggg ccgccgagat cggggtcgag
    26581 ctgttcgtgg tggacgacgg ctggttcggc gcccgcacca gcgaccgcgc cggcctcggc
    26641 gactggacgc ccaaccccga ccgcttcccg cacggcctca agccgctcgc cgaccaggtg
    26701 cacgggctcg gcatgcggtt cggcatctgg gtcgagcccg agatggtcaa cccggacagc
    26761 gacctgtacc gc
//
