LOCUS       NZ_AP024135            13467 bp    DNA     linear   CON 08-NOV-2024
DEFINITION  Streptomyces sp. EAS-AB2608 strain NBRC 114648 chromosome.
ACCESSION   NZ_AP024135
VERSION     NZ_AP024135.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. EAS-AB2608
  ORGANISM  Streptomyces sp. EAS-AB2608
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Kitasatosporales; Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Okubo,S., Ena,E., Okuda,A., Kozone,I., Hashimoto,J., Nishitsuji,Y.,
            Fujie,M., Satoh,N., Ikeda,H. and Shin-Ya,K.
  TITLE     Identification of functional cytochrome P450 and ferredoxin from
            Streptomyces sp. EAS-AB2608 by transcriptional analysis and their
            heterologous expression
  JOURNAL   Appl Microbiol Biotechnol 105 (10), 4177-4187 (2021)
   PUBMED   33944982
  REMARK    DOI:10.1007/s00253-021-11304-z
REFERENCE   2  (bases 1 to 9320785)
  AUTHORS   Okubo,S., Ena,E., Okuda,A., Kozone,I., Hashimoto,J., Nishitsuji,Y.,
            Fujie,M., Satoh,N., Ikeda,H. and Shinya,K.
  TITLE     Direct Submission
  JOURNAL   Submitted (28-OCT-2020) Contact:Shinya Okubo Eisai Co., Ltd.;
            Tokodai 5-1-3, Tsukuba 300-2635, Japan
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Newbler v. 2.9
            Genome Coverage                   :: 53x
            Sequencing Technology             :: Miseq; PacBio RS II
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_019703895.1-RS_2024_11_06
            Annotation Date                   :: 11/06/2024 09:16:33
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,174
            CDSs (total)                      :: 8,084
            Genes (coding)                    :: 7,890
            CDSs (with protein)               :: 7,890
            Genes (RNA)                       :: 90
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 194
            CDSs (without protein)            :: 194
            Pseudo Genes (ambiguous residues) :: 0 of 194
            Pseudo Genes (frameshifted)       :: 87 of 194
            Pseudo Genes (incomplete)         :: 132 of 194
            Pseudo Genes (internal stop)      :: 10 of 194
            Pseudo Genes (multiple problems)  :: 32 of 194
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 13:41:52
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 5773545
            Orig. end                         :: 5787012
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            AP024135.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..13467
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="aminopolycarboxylic-acid"
                     /region_number="18"
                     /rules="(AesA and AesB and AesC)"
                     /tool="antismash"
     cand_cluster    1..13467
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(AesA and AesB and AesC)"
                     /kind="single"
                     /product="aminopolycarboxylic-acid"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..13467
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[5000:8467](-)"
                     /cutoff="10000"
                     /detection_rule="(AesA and AesB and AesC)"
                     /neighbourhood="5000"
                     /product="aminopolycarboxylic-acid"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(5001..8467)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(AesA and AesB and AesC)"
                     /neighbourhood="5000"
                     /product="aminopolycarboxylic-acid"
                     /protocluster_number="1"
     gene            202..786
                     /locus_tag="K6K39_RS25755"
                     /old_locus_tag="EASAB2608_05264"
     CDS             202..786
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018471022.1"
                     /locus_tag="K6K39_RS25755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EASAB2608_05264"
                     /product="RES family NAD+ phosphorylase"
                     /protein_id="WP_260335628.1"
                     /transl_table=11
                     /translation="MAGDRRRGRAPRLADIHFHGGRFDGTVLDQYHSLYLAETALTALA
                     ESVLRSRPFASPDGDRTIPYRAVWQRSLSCLRTRSDLILVSLVSGADLAAVCQDATLLE
                     DEANYARARRWSSEIRAQASDVMGLIWESRRNRSAHAMVLHHDRCLGQDGSPLEVLPDR
                     GIPDLGAAEGRERADELLAPLRARIARPERP"
     gene            complement(861..2126)
                     /locus_tag="K6K39_RS25760"
                     /old_locus_tag="EASAB2608_05265"
     CDS             complement(861..2126)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0015297 - antiporter activity [Evidence
                     IEA]"
                     /GO_process="GO:0006812 - monoatomic cation transport
                     [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /GO_process="GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1117:
                     sodium/hydrogen exchanger"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015493367.1"
                     /locus_tag="K6K39_RS25760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EASAB2608_05265"
                     /product="cation:proton antiporter"
                     /protein_id="WP_260336153.1"
                     /transl_table=11
                     /translation="MTTNQLFALFSDLALLLVLAHLLGALARRFSQPAVIGEVLAGILL
                     GPTLLGHEVSDFLFPSDIRPMLTALADVGMAVFMFIVGLELDRKILRGTGRLAATVSVS
                     SILLPFGLGALLALLLAEDHAPDHRLGFVLFMGTAMSVTAFPVLARILTDREMQHTPVG
                     GLALACAAIGDVLAWCMLAAVVALAGGGGAGPWYLLLLVPYTGVMLWVVRPLLRRLLAA
                     GAGTARLSPAALTAVLAGLLVSGAVTEKIGLHFIFGAFFFGVVMPKESTERLRADITDR
                     IGEVSSHLLLPVFFISVGLKVDLSDLGRSGWLDFGLILLVAVSGKFLGAFLSARAHGVT
                     ARQSAVLATLMNTRGLTELIILTAGLQLGVLDERLFSLMVAMAVVTTAMAGPLLSLFQP
                     RPLADHPLVPAARDAQPPAARH"
     misc_feature    complement(1980..1982)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            2320..3582
                     /locus_tag="K6K39_RS25765"
                     /old_locus_tag="EASAB2608_05266"
     CDS             2320..3582
                     /EC_number="3.1.1.-"
                     /GO_process="GO:0046677 - response to antibiotic [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014048816.1"
                     /locus_tag="K6K39_RS25765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EASAB2608_05266"
                     /product="erythromycin esterase family protein"
                     /protein_id="WP_221334922.1"
                     /transl_table=11
                     /translation="MTNGEVRRWLAEHAWPLKEPDGGYGGPAEPGDADLAPLREVLRDV
                     RVLGMGEATHGTAEFFRLKHRLLRFLVRDLGCTTLALEASASAARAVDDHVRHGTGDAA
                     AALAGLGFWTWRTREMLDVVEWLRAHNRTVPPEHAVRFVGIDPQRCGPSLAAVEAVLRA
                     AAPERAPLADGPLAALADAPAGSLAACGPELLAAADDLTAFLEQERPRLADRAGAEAAD
                     RALGHARLIAAAADVAARPPHGTGAEPGALAARDRHMARAVLAAAERAAGPVAVWAHNG
                     HVASEPYGGGVPAMGQHLRARLGARYYALGLLFGAGAFRARPGTAGRRPPRRHTVDAAG
                     PRSLEGQLAAATPGDHLIDLRAGRADPAVARWLDTRHFVRAFGAGVPRVTYRMQLAATV
                     PGRAYDGLAYVARSTPSVPLD"
     gene            complement(3607..5001)
                     /locus_tag="K6K39_RS25770"
                     /old_locus_tag="EASAB2608_05267"
     CDS             complement(3607..5001)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0042910 - xenobiotic transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0006855 - xenobiotic transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1086: MATE efflux
                     family protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020548826.1"
                     /locus_tag="K6K39_RS25770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EASAB2608_05267"
                     /product="MATE family efflux transporter"
                     /protein_id="WP_221334923.1"
                     /transl_table=11
                     /translation="MPPAFARLLTDSRALATLAVPLALTQLAQVALTTTDTVMMGLIGT
                     EALAAGGLAMVIFNQLRTMGVGLVTAVGNQIAAADARAEADESDPRAREEVRDLVRASL
                     LLATLAGLAGAVLMVLVGHAVVLLGQDPDVVDAAKPVLYAMAPGLIPCLWFQAIRQFTV
                     GMGRPQALLRITIASIAVNAGLNWLFIHGTWGLPELGLPGIGLATTTVYALSFLALYAS
                     ARRDARLAPLLSLRIWRTRPATLRRLASLGAPIAATYGSEAGFFSVVALLVGSFGTAAL
                     AAHTAVNQLVYIVFQIAVGLSHAASLGVSRELALGNTAAARRLKTTALACAAAVMAAVA
                     VVYVTVPRLVLAPFFDTGDASATDIATHLLLVAAVLQFFDCTQNIGVGLLRGLDDTKGG
                     FRVTLVGYWLIGLPAAALLGPAAGLDTLGVWLGLLTGLAATAVLLLRRFHRGVDALEPT
                     AAPAAA"
     gene            complement(5001..6086)
                     /locus_tag="K6K39_RS25775"
                     /old_locus_tag="EASAB2608_05268"
     CDS             complement(5001..6086)
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA]"
                     /GO_process="GO:0006535 - cysteine biosynthetic process
                     from serine [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     aminopolycarboxylic-acid: AesC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PALP"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1081: cysteine synthase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003955046.1"
                     /locus_tag="K6K39_RS25775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EASAB2608_05268"
                     /product="cysteine synthase family protein"
                     /protein_id="WP_221334924.1"
                     /sec_met_domain="AesC (E-value: 1.1e-188, bitscore: 625.2,
                     seeds: 5, tool: rule-based-clusters)"
                     /sec_met_domain="PALP (E-value: 2e-57, bitscore: 193.8,
                     seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAPSPHPLHRPAVVRRVSELIGATPLFELCRTESDARLLLKLEQF
                     NPTGTAKIRMARQMVVDAEERGLLRPGGRIIESTSGNTGLGLAVVAAERGYTFTAVVDH
                     HAAKDKLRAMRAMGTELVYVADAGDDDLATAAREELAEKMAAETDNAYFTEQHNNPANA
                     VGYHPVAHELDAALDGRVDVLIGAVGTGGGLFGTGRELRRTVPGVRIVGVEPEGSIAFG
                     PPAHDYHQSGTGTPEGATIGVMVDYDLLDEGVKVGDVAAFATARAVARRTGLLIGGSAG
                     GVVHAALARLPALPPGATMVALVNDGGEKYLDTVFDDDWMAARDLLSPGVERAVEETLA
                     KLRRTDPVPSPAPAHPTQDQI"
     gene            complement(6099..7448)
                     /locus_tag="K6K39_RS25780"
                     /old_locus_tag="EASAB2608_05269"
     CDS             complement(6099..7448)
                     /EC_number="5.1.1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     aminopolycarboxylic-acid: AesB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Orn_Arg_deC_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1264: diaminopimelate decarboxylase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012998464.1"
                     /locus_tag="K6K39_RS25780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EASAB2608_05269"
                     /product="alanine racemase"
                     /protein_id="WP_221335637.1"
                     /sec_met_domain="AesB (E-value: 7e-208, bitscore: 689.0,
                     seeds: 5, tool: rule-based-clusters)"
                     /sec_met_domain="Orn_Arg_deC_N (E-value: 1.9e-22, bitscore:
                     78.7, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAPLRSHTTPEVRALLADPLLRDLSHGLGGPYHALFPARFDANA
                     GAFGRALAEAGVDGTVYFAKKANKAAVFPERAAELGLGVDVASHGELREALAHGVRGTD
                     LVVTGPAKSERLLRVAVLQGALVAVDALDELDRLAALASGLGRTARVLLRRLPPGPPSR
                     FGLDDAETRAALRRCADGPVDVAGFSFHLSGYDVRQRADLAGRLVRDCQDARELGLHPD
                     RISIGGGFAVDYVGAEDWRRFTAADRPEHYHAGRTFPGGWYPYHSPVAGADALRAILAA
                     VPAGERDSLAGLLRAAGVRLLVEPGRALLDQAGCTVFAVQGVKDRDGYAILTVDGTSLS
                     LSEQWFGSEFLPDPVLVPGVPDAGSAAGPYPACVGAASCLESDMLTWRKIPFPVRPAVG
                     DLLVYLNTAGYQMDSNESPFHELPLPPKVVVEQVSDGTAARLRWHLDRHP"
     gene            complement(7445..8467)
                     /locus_tag="K6K39_RS25785"
                     /old_locus_tag="EASAB2608_05270"
     CDS             complement(7445..8467)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     aminopolycarboxylic-acid: AesA"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1158: ornithine cyclodeaminase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012998463.1"
                     /locus_tag="K6K39_RS25785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EASAB2608_05270"
                     /product="ornithine cyclodeaminase family protein"
                     /protein_id="WP_221334925.1"
                     /sec_met_domain="AesA (E-value: 1e-171, bitscore: 568.7,
                     seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTGTDHRQGEPMASDDTALRILSTGDVAGIDIALPDVVSVVEQAY
                     RTLAEGRSANPRKLTVTPEDGHSVAYAMLGRDGERNVVAVKTSYKYGLHEDRDKQHYYT
                     TLTLYDDVTGLPVAMMDCGRVGALRTPAVSALLARELAAPGSRSALVIGTGTQGRLALP
                     FLLTTLPRLDRLMLFGTHPEGIRAARAQLRAHFPDRELEIVSDLRAAAGQADIVLATAG
                     PRTPASVPAEWLRPAALSVLVGYGIAPSTLHRADRVIATSAAQMRVTGTDMADETGELR
                     AVDAEFPDVLAGRAAGRTDLGQRIFAYNSGLVVTDIALGHRFAQLALAQGLGTVVPLWR
                     "
     gene            complement(8464..9453)
                     /locus_tag="K6K39_RS25790"
                     /old_locus_tag="EASAB2608_05271"
     CDS             complement(8464..9453)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TauD"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012998462.1"
                     /locus_tag="K6K39_RS25790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EASAB2608_05271"
                     /product="TauD/TfdA family dioxygenase"
                     /protein_id="WP_221334926.1"
                     /sec_met_domain="TauD (E-value: 3.8e-08, bitscore: 32.3,
                     seeds: 119, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPTAAVPLRLLDPDSAAQLTSAARTLLAPFDGDPTHPDLLAHVPA
                     AAAALSDGVRHACRPVDTPDGLYVLRGLPVDDASLGPTPGHWSAAGDAGALYDAVLLLL
                     STVLGTPIAWAGQQNGRFVHNIVPSPGHEREQTGASSSVLLSPHTEDAFHPGRAHLLVL
                     ACLRNPDAVATTAASVRRVRLARSDVELLSRPALPILPDDAYAEPEAYDGGPPPVPTLW
                     AAEDGLTLRFDPAYTPLDQASAEHRAAYGRLADELARVSVAVTLAPGDILVLDNDLVVH
                     GRVPFTARYDGTDRWLKRSSVRVPGRRTRPPAERSEHGYGQAALAAYR"
     misc_feature    complement(9253..9255)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    9528..9546
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: medium, score: 27.3"
                     /tool="antismash"
     misc_feature    9595..9613
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: weak, score: 24.99"
                     /tool="antismash"
     misc_feature    complement(9600..9618)
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: weak, score: 21.97"
                     /tool="antismash"
     gene            9647..11203
                     /locus_tag="K6K39_RS25795"
                     /old_locus_tag="EASAB2608_05272"
     CDS             9647..11203
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1068:
                     extracellular solute-binding protein family 5"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006138034.1"
                     /locus_tag="K6K39_RS25795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EASAB2608_05272"
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="WP_221334927.1"
                     /transl_table=11
                     /translation="MDLTRRQLLWAGGALGATALLAGCADSDDGRPGGSATGGSGKPRK
                     GGTLRVGALGRAGAVTRDPHGTQANESDYLILSLIYDTLTVPGRTPNTAPRLAARWTPS
                     ADLKTWRFTLAKGATFHDGSPVTAKDVVFSLRRLRATPAGASRLPGIQARNITAEGTGT
                     VVLVSDYANAELPQLTRLTTFVVPDGTADKDMAEAPGTGPFTLDWFRGGNARLVRNDRW
                     YGGEVHLDAIEVRIFESPQAMASALLAGQIDLASNVGAVAARTAKGRGDIQTVRRPNDM
                     AMPLVLRTADGPFADPKVREALRLAVDREAMVKQVLSGYGSVANDVLGTGDPAYAKDLP
                     QRTRDLARARKLLKEAGFDTSKTYELRTTEDISGLAESATLFASQVREAGVKIKVVKQE
                     SAVFWDKTWLKADLYTTYWGTNDSVVFFASKTMVSDSAQNEAGFKDRAFDVAYRKAIGT
                     ADATERARLLKELQRIEYERSGYLLWGMADGIDLAGSAVRGLPTLPGYGRVQLEQAWLA
                     R"
     gene            11188..12195
                     /locus_tag="K6K39_RS25800"
                     /old_locus_tag="EASAB2608_05273"
     CDS             11188..12195
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1118:
                     binding-protein-dependent transport systems"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020548824.1"
                     /locus_tag="K6K39_RS25800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EASAB2608_05273"
                     /product="ABC transporter permease"
                     /protein_id="WP_059252983.1"
                     /transl_table=11
                     /translation="MAGPLTAGTAAPALGEGAAPPRVLRHLARLGALLLKRAALLATLL
                     ALVFVTIELLPGDAATATSERGESAADVARRRALLGLDRPLPTRFWDWMSGLPTGDLGT
                     SARGERVTDLISTAFPNTLLLGGIALLLTAVLSLALGCWAALRPGGRLDRAVSGTATAV
                     LALPEFVVAVALVLVLSLWTGWLPAVTLTDADGNPASWTMLILPALALTVPQTGWNTRI
                     VRAALADEARAPHVETALLDGLPPHRVLTHHVLPGALPTIAAGLATSTGMLLGGAVVVE
                     TIFNYPGVGAVLASAVTDRDTPVIAGVTALSGAVITGVLLAADLVRDAVAGGRR"
     gene            12192..13148
                     /locus_tag="K6K39_RS25805"
                     /old_locus_tag="EASAB2608_05274"
     CDS             12192..13148
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1085:
                     binding-protein-dependent transport systems"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010987023.1"
                     /locus_tag="K6K39_RS25805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EASAB2608_05274"
                     /product="ABC transporter permease"
                     /protein_id="WP_221334928.1"
                     /transl_table=11
                     /translation="MSPDSTAGRPTGTPPSPPAPGRPAPRLRLRRGPSSGHTPRTPAPR
                     PRPGRSPRATVLRTLPALLLTGLALVGPWIAPHPVDAPRTAPYAGPGADAVLGGDQLGR
                     DVLSRLLAGGRELVLSALLVAVLVTGTAAVLGAIGAVRPLVGRLVERTADMLMLLPAVL
                     GILLVTLSWPGGGRLAVIVAAVVLGVPYAVRLTAGAAAPVAASGYVEAAAAGGERLWYL
                     VVREILPNLRATLLALFGLRFVAAVYLVATAGFLQVGPQPPAADWALMIRENSSGILLN
                     PWAVVAPSVAIGLLALSVNLAAATLVPQTGRKAVTVL"
     gene            13145..13333
                     /locus_tag="K6K39_RS25810"
                     /old_locus_tag="EASAB2608_05275"
     CDS             13145..13333
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="K6K39_RS25810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="EASAB2608_05275"
                     /product="hypothetical protein"
                     /protein_id="WP_221334929.1"
                     /transl_table=11
                     /translation="MSHASDRYPKHPAVPDDQVPAVRVDALTVTAADGRHLLHEASLTL
                     HPGRLVALTGRKAVTVL"
ORIGIN
        1 tggtccggcg cctggacgac ggcgtccccc gcgccggtga cagcccggcc gccgtgcggg
       61 agagcatcga cgcgctgtgg gaccggctcc ggcggatgcg gcaggagatg cgctccgagc
      121 tgggtgagtt ccggacggat tccgggcgtt gagggaccgg cgcacgccgt ctcgccgccg
      181 tgcgcgccag ggctcggcat agtggcaggt gatcggcgcc ggggccgggc gccgagactg
      241 gcggacatcc acttccacgg gggccgtttc gacggcacgg tgctggacca gtaccacagc
      301 ctgtacctgg cggagaccgc gctgaccgcg ctcgcggaga gcgtgctccg ctcccggccc
      361 ttcgcatcgc cggacgggga ccgtacgatc ccctaccgcg ccgtctggca gcgctcgctg
      421 agctgtctgc gcacccggtc cgacctgatc ctggtctccc tggtcagcgg cgccgacctg
      481 gccgccgtct gccaggacgc caccctcctg gaggacgagg ccaactacgc gcgggcgcgg
      541 cgctggtcga gcgagatccg ggcgcaggcg tccgacgtca tggggctgat ctgggagtcg
      601 cggcgcaacc ggtccgcgca tgccatggtg ctccaccacg accgctgcct gggccaggac
      661 ggctcaccgc tggaggtgct gcccgaccgc ggcatcccgg acctcggcgc agcggagggc
      721 cgggagcggg ccgacgagct gctcgcgccg ctgcgggcga ggatcgcgcg acccgaacgg
      781 ccctgacgcc ccggcgcgcc ccgtccgcgg acccgcgcgc cgccctcctc gcccacggac
      841 cgggccccgc cccggtgggg tcagtgtctg gcggcgggcg gctgggcgtc gcgggccgcc
      901 gggacgaggg ggtgatcggc gagggggcgc ggctggaaga gcgacagaag cggcccggcc
      961 atcgcggtcg tcacgacggc catggcgacc atcagggaga acaaccgctc gtcgagcacc
     1021 ccgagttgca gcccggcggt caggatgatc agctcggtca ggcccctggt gttcatgagc
     1081 gtggcgagca ccgccgactg gcgcgccgtg accccgtgcg cccgggcgct caggaacgcg
     1141 ccgaggaatt tgccgctgac cgcgaccagc aggatgagac cgaagtccag ccatccggac
     1201 cgccccaggt ccgacaggtc gaccttcagg cccacgctga tgaagaacac cggcagcagc
     1261 agatggctgc tcacctcgcc gatgcggtcg gtgatgtcgg cgcgcagccg ctcggtggac
     1321 tccttcggca tcaccacccc gaagaagaac gcgccgaaga tgaagtgcag gccgatcttc
     1381 tccgtgacgg cccccgacac gagcagcccg gcgagcacgg ccgtcagcgc cgcggggctc
     1441 agccgggccg tgccggcacc ggcggcgagc agccggcgca acagcggacg caccacccac
     1501 agcatcaccc cggtgtacgg cacgagcagc agcaggtacc acgggccggc gccgcccccg
     1561 ccggccagcg cgaccacggc ggcgagcatg caccacgcga ggacgtcacc gatcgcggcg
     1621 caggccagcg ccagtccgcc gaccggcgtg tgctgcatct cgcggtccgt gagaatgcgg
     1681 gccagcaccg gaaaggcggt caccgacatc gccgtaccca tgaacagcac gaaacccagc
     1741 cggtgatccg gggcgtggtc ctcggccagc agcagggcga gcagcgcacc gagtccgaac
     1801 ggcagcagaa tcgaggagac cgagacggtc gccgccagcc gtccggtgcc gcggaggatt
     1861 ttccggtcga gttccaggcc cacgatgaac atgaatacgg ccatgccgac atccgcgagt
     1921 gccgtgagca tcggccggat atcgctggga aacaggaagt ccgatacctc gtggcccagt
     1981 aatgtgggcc cgagcaggat gcccgcgagc acctcgccga tgaccgcggg ttgggagaat
     2041 cgccgtgcca gcgcgcccag aagatgggcg agaacgagaa ggagggccag gtcggagaag
     2101 agcgcgaaca gttggttcgt ggtcaccggt ccctgccttg atgacgggcc gcgtgcgccg
     2161 cccggaattc gatgaggtgc cgccgacgtg ccccgccatg cttcgttgta ccggcccgct
     2221 ttgtcaacgg cggcaatctt gaacacgcgc atggccggtg aaaaggagac cggaaatccc
     2281 cttgacggag aacgccgggg aatggaaaac ggggagagaa tgacgaacgg ggaagtgcgc
     2341 cggtggctcg cggagcatgc ctggccgctg aaagagccgg acggcgggta cggcgggccc
     2401 gcggaaccgg gcgacgcgga cctggcgccg ctgcgcgagg tcctgcggga cgtccgcgtc
     2461 ctgggcatgg gcgaggcgac gcacgggacc gccgagttct tccggctcaa gcaccgcctg
     2521 ctgcgcttcc tggtccggga cctcggctgc accaccctgg ccctggaggc gagcgcctcg
     2581 gccgcgcggg ccgtggacga ccacgtacgg cacggaaccg gcgatgccgc cgccgcgctc
     2641 gccgggctcg gcttctggac ctggcgcacc cgcgagatgc tcgacgtcgt cgagtggctg
     2701 cgcgcccaca accgcacggt cccgccggag cacgccgtgc gcttcgtcgg gatcgacccc
     2761 cagcgctgcg gtccctccct ggccgccgtc gaagccgtgc tgcgcgccgc cgccccggag
     2821 cgcgcccctc tcgccgacgg tccgctcgcc gccctggcgg acgccccggc gggctcactg
     2881 gccgcctgcg gccccgaact cctcgccgcc gccgacgact tgacggcctt cctcgaacag
     2941 gagcggcccc ggctggccga ccgggccgga gccgaggcgg cggaccgtgc gctcggccac
     3001 gcgcgcctga tcgccgcggc ggccgacgtg gccgcccggc cgccgcacgg caccggcgcc
     3061 gagccgggcg cgctcgcggc ccgtgaccgg cacatggcgc gggcggtgct cgcggcggcg
     3121 gagcgggccg ccggaccggt ggccgtctgg gcgcacaacg ggcatgtggc gagcgagccg
     3181 tacggcggcg gggtgccggc catggggcag cacctcagag cgcgcctcgg cgcgcgctac
     3241 tacgccctgg gcctgctctt cggggcgggc gccttccgcg cccggcccgg aaccgccggg
     3301 cgccgcccgc cgaggagaca cacggtcgac gcggccggcc cgcggtccct ggaggggcag
     3361 ctcgccgccg ccacccccgg ggaccacctg atcgacctgc gggccggccg ggccgacccc
     3421 gccgtcgccc ggtggctgga cacccggcac ttcgtacggg ccttcggtgc cggggtgccc
     3481 cgcgtgacgt accggatgca gctggccgcg acggtgcccg gccgggcgta cgacggcctg
     3541 gcgtacgtgg cccgctcgac cccctccgtc ccgctggact gaagccctcc ggcaggggcg
     3601 cgtccctcag gccgcggccg gggcggccgt cggctccagg gcgtcgaccc ctcggtggaa
     3661 gcgccgcagg aggagcaccg cggtggcggc caggccggtg agcaggccga gccagacgcc
     3721 gagggtgtcc aggccggcgg ccgggccgag gagcgcggcg gccggcaggc cgatcagcca
     3781 gtacccgacg agcgtgaccc ggaagccgcc cttggtgtcg tccaggccgc gcagcaggcc
     3841 gacgccgatg ttctgggtgc agtcgaagaa ctgcaggacg gcggcgacga gcagcagatg
     3901 cgtggcgatg tcggtcgcgg acgcgtcgcc ggtgtcgaag aacggggcca gcaccaggcg
     3961 cggcacggtg acgtagacga cggccacggc ggccatgacc gccgcggcgc aggccagggc
     4021 cgtggtcttc aggcgccgcg ccgcggccgt gttgcccagg gcgagttccc ggctgacacc
     4081 gagggacgcg gcgtgcgaga ggcccacggc gatctggaag acgatgtaga cgagttggtt
     4141 gacggcggtg tgcgccgcca gcgcggcggt gccgaagctg ccgacgagca gggcgacgac
     4201 ggagaagaag cccgcctcgg agccgtaggt ggcggcgatc ggcgcgccga gggaggccag
     4261 gcggcgcagg gtggcggggc gggtgcgcca gatgcgcagc gagagcagcg gggcgagccg
     4321 ggcgtcgcgg cgggcggagg cgtacagggc gaggaacgac agggcgtaca cggtggtcgt
     4381 ggccaggccg atgcccggca ggcccagttc cggcaagccc caggtgccgt ggatgaacag
     4441 ccagttgagt ccggcgttga ccgcgatcga ggcgatcgtg atgcgcagca gcgcctgcgg
     4501 ccggcccatg ccgacggtga actggcggat cgcctggaac cacagacagg ggatcaggcc
     4561 gggcgccatg gcgtacagca cgggcttcgc cgcgtcgacg acgtccgggt cctggccgag
     4621 caggaccacg gcgtgcccga cgagcaccat cagcaccgcg ccggccagcc ccgccagcgt
     4681 ggccagcagc aggctcgccc gcaccaggtc ccgtacctct tcccgggccc gcggatcgct
     4741 ctcgtccgcc tcggcgcgcg cgtcggccgc ggcgatctgg ttgccgacgg cggtgacgag
     4801 cccgacgccc atggtgcgca gctggttgaa gatcaccatg gcgagaccgc cggcggcgag
     4861 cgcctcggtg ccgatcaggc ccatcatgac ggtgtcggtg gtcgtcagtg cgacctgcgc
     4921 gagctgggtg agggcgagcg ggacggcgag cgtggccagg gcccggctgt cggtgaggag
     4981 gcgggcgaac gcggggggca tcagatctgg tcctgggtcg ggtgcgcggg ggcgggggac
     5041 gggacggggt cggtgcggcg gagcttggcg agggtctcct ccaccgcgcg ttcgacgccg
     5101 ggggagagca ggtcgcgggc ggccatccag tcgtcgtcga agacggtgtc caggtacttc
     5161 tcgccgccgt cgttgaccag cgcgaccatg gtggccccgg gcggcagcgc gggcagccgg
     5221 gccagcgccg cgtgcaccac cccgccggcc gagccgccga tcagcagccc ggtgcggcgc
     5281 gcgacggccc gcgcggtggc gaacgccgcc acgtcgccga ccttcacgcc ctcgtccagc
     5341 aggtcgtagt cgaccatgac gccgatggtg gcgccctcgg gcgtgccggt gcccgactgg
     5401 tggtagtcgt gcgcgggcgg tccgaacgcg atggaccctt ccggctcgac cccgacgatc
     5461 cgcacaccgg gcacggtccg gcgcagctcg cggccggtgc cgaacagccc gccgccggtg
     5521 cccacggcac cgatgagcac gtcgacacgg ccgtcgaggg cggcgtcgag ttcatgggcg
     5581 accgggtggt agccgaccgc gttggccggg ttgttgtgct gctcggtgaa gtaggcgttg
     5641 tcggtctcgg cggccatctt ctcggccagc tcctcccggg ccgccgtggc caggtcgtcg
     5701 tcgcccgcgt cggcgacgta gacgagttcc gtgcccatgg cccgcatggc gcgcagcttg
     5761 tccttggccg cgtggtggtc gaccaccgcc gtgaaggtgt agccgcgttc ggcggcgacc
     5821 acggcgaggc ccagaccggt gttgccggag gtcgactcga tgatgcggcc accggggcgc
     5881 agcagtccgc gctcctcggc gtcgaccacc atctggcggg ccatgcgtat cttggccgtg
     5941 cccgtcgggt tgaactgctc cagcttcagc agcagccgtg cgtcgctctc cgtgcggcac
     6001 agctcgaaca ggggggtggc accgatgagt tcggagaccc ggcgcacgac ggccggacgg
     6061 tgcagggggt gcgggctcgg ggccatgggc ggaactccct acgggtggcg gtcgaggtgc
     6121 cagcggaggc gggcggcggt gccgtcggag acctgttcta cgacgacctt gggcggcagg
     6181 ggcagctcgt ggaacggcga ctcgttggag tccatctggt agccggccgt gttgaggtag
     6241 accagcaggt caccgacggc cggccggacc gggaagggta tcttgcgcca ggtcagcatg
     6301 tcggactcca ggcagctggc cgcgcccacg caggcggggt acggtcccgc ggcggagccg
     6361 gcgtccggga cgcccggcac cagcaccggg tccggcagga actcgctgcc gaaccactgc
     6421 tccgacaggc tcaggctggt gccgtccacg gtgaggatcg cgtagccgtc gcggtccttg
     6481 acaccctgca cggcgaagac cgtacagccg gcctggtcca gcagcgcccg cccgggctcc
     6541 accagcagcc ggaccccggc ggcccgcaac agcccggcga ggctgtcccg ttcaccggcc
     6601 ggtacggccg ccaggatcgc gcgcagggcg tcggcgccgg cgacggggga gtggtacggg
     6661 taccagccgc cggggaaggt ccggccggcg tggtagtgct cgggccggtc ggcggcggtg
     6721 aaccggcgcc agtcctcggc accgacgtag tccaccgcga agccgccgcc gatgctgatg
     6781 cggtccgggt gcaggcccag ctcccgggcg tcttggcagt cccggaccaa ccgcccggcc
     6841 aggtcggcgc gttgccggac gtcgtagccc gacagatgga agctgaagcc cgcgacgtcg
     6901 accgggccgt cggcgcagcg ccgcagcgcc gcccgggtct cggcgtcgtc cagcccgaac
     6961 ctgctgggcg ggccgggcgg cagccggcgc agcagcaccc gcgcggtgcg gccgaggccg
     7021 gacgccagcg ccgcgaggcg gtccagttcg tccagggcgt ccacggcgac gagcgcgccc
     7081 tgcaggacgg cgacccgcag cagccgctcg gacttggccg gtccggtgac caccaggtcg
     7141 gtcccgcgca ccccgtgggc cagcgcctcg cgcagctcac cgtggctcgc cacgtccacg
     7201 cccaggccca gctcggcggc ccgctcgggg aagacggccg ccttgttggc cttcttggcg
     7261 aagtacaccg tgccgtcgac gcccgcctcg gccagcgccc ggccgaaggc gccggcgttg
     7321 gcgtcgaacc gcgcggggaa cagcgcgtgg taggggccgc cgaggccgtg gctcaggtcg
     7381 cgcagcagcg ggtcggccag cagggcgcgc acctcgggcg tggtgtgcga gcgcagcggg
     7441 gcggtcacct ccacagcggc accaccgtgc ccaggccctg ggcgagggcg agctgcgcga
     7501 agcggtggcc gagggcgatg tcggtgacga ccagcccgct gttgtacgcg aagatccgct
     7561 gccccaaatc ggtacggccg gccgcgcggc ccgcgagcac gtcggggaac tcggcgtcca
     7621 cggcgcgcag ttcgcccgtc tcgtcggcca tgtcggtgcc ggtgacgcgc atctgggctg
     7681 cgctggtggc gatcacccgg tcggcccggt gcagggtgga gggcgcgatg ccgtagccga
     7741 cgagcaccga cagggcggcc gggcggagcc actcggcggg caccgaggcg ggggtgcggg
     7801 ggccggcggt ggccagcacg atgtcggcct gcccggccgc cgcccgcaga tcggagacga
     7861 tctccagctc gcggtcgggg aagtgcgcgc gcagctgggc acgcgccgcc cggatgccct
     7921 ccgggtgggt gccgaacagc atcagccggt ccagccgggg cagcgtcgtc agcaggaacg
     7981 gcagcgcgag ccggccctgg gtgccggtgc cgatgacgag cgcgctgcgg ctgccgggcg
     8041 cggcgagttc gcgggcgagc agcgcggaga cggccggggt gcgcagggca ccgacccggc
     8101 cgcagtccat catggccacg ggcaggcccg tcacatcgtc gtagagggtc agcgtcgtgt
     8161 agtagtgctg cttgtcgcgg tcctcgtgca ggccgtactt gtacgacgtc ttgaccgcga
     8221 ccacgttgcg ctccccgtcc cggccgagca tggcgtaggc gacggagtgg ccgtcctcgg
     8281 gggtgacggt gagcttgcgc ggattggcgg agcggccctc cgccagggtg cggtacgcct
     8341 gctccaccac ggagacgacg tcgggcagtg cgatgtcgat accggccacg tcgccggtgc
     8401 tgagtatgcg cagggcggtg tcgtcggacg ccatgggctc cccctgtcgg tggtcggtgc
     8461 cggtcatcgg tacgccgcca gggcggcctg gccgtagccg tgctcggagc gttcggcggg
     8521 cgggcgggta cggcggcccg gcacccgtac agaggaacgt ttcagccagc ggtcggtgcc
     8581 gtcgtagcgg gcggtgaagg ggacccggcc gtggacgacg aggtcgttgt cgagcaccag
     8641 gatgtcgccg ggggccagcg tcaccgccac cgagacccgg gcgagttcgt ccgccaggcg
     8701 tccgtaggcc gcccggtgct ccgcggaggc ctggtccaag ggtgtgtagg cggggtcgaa
     8761 gcgcagggtc aggccgtcct cggccgccca cagggtgggc accggcgggg gaccgccgtc
     8821 gtacgcctcg ggctcggcgt aggcgtcgtc gggcaggatc ggcagggccg ggcggctgag
     8881 cagctccacg tcggagcggg ccagccggac ccggcgcacg ctggccgccg tggtggcgac
     8941 ggcgtcgggg ttgcgcaggc aggcgaggac cagcagatgg gcccggccgg ggtggaaggc
     9001 gtcctcggtg tgcgggctga gcagcacgct gctgctggcg ccggtctgct cccgctcgtg
     9061 cccgggcgag ggcacgatgt tgtgcacgaa ccggccgttc tgctggccgg cccaggcgat
     9121 cggggtgccg agcacggtcg agagcagcag caggacggcg tcgtacaggg cgcccgcgtc
     9181 cccggcggcc gaccagtggc cgggcgtggg gccgagcgag gcgtcgtcga cgggcagtcc
     9241 gcgcagcacg tataacccgt cgggggtgtc caccgggcgg caggcgtgcc ggacgccgtc
     9301 actcaacgcg gcggctgccg cggggacgtg ggcgagcagg tcggggtggg tggggtcgcc
     9361 gtcgaagggg gcgaggaggg tgcgggcggc gctggtcagc tgtgccgccg agtcggggtc
     9421 gagcagacgt aggggtacgg ctgccgtcgg catgggtgaa ccgtccgttc cggtgcgggg
     9481 cgggtgcggg gcggtgcggc ccaggcaaca tagccagccc aaagagatca ggcaaggctt
     9541 acctaagttg agttgtggat cacagtgcgt gcgcccttgt cacacggggc gtgcacaggg
     9601 taggcaaacc taagcaatcg ccgaccgtgg gaaatcgagg caccaagtgg acctgacgcg
     9661 acgtcaactc ctgtgggcgg gcggtgctct cggcgccacc gctctgctcg ccggctgcgc
     9721 cgacagcgac gacggccggc cgggcgggtc cgccaccggc ggctccggca agccgcgcaa
     9781 gggcggcacc ctgcgcgtcg gcgccctcgg ccgggccggc gccgtcaccc gcgacccgca
     9841 cggcacccag gccaacgaga gcgactacct catcctcagc ctgatctacg acaccctcac
     9901 cgtccccggc cgcacaccca acaccgcccc ccggctcgcc gcccgctgga cgccctcggc
     9961 cgacctcaag acctggcgat tcaccctcgc caagggcgcc accttccacg acggctcccc
    10021 ggtcacggcc aaggacgtcg tcttctcgct gcgccggctg cgcgccaccc cggccggcgc
    10081 ctcccggctc cccggcatcc aggccaggaa catcaccgcc gaggggaccg gcaccgtcgt
    10141 cctcgtctcc gactacgcca acgccgaact cccgcagctc acccgcctca ccaccttcgt
    10201 cgtccccgac ggcacggccg acaaggacat ggccgaggcg cccggcaccg gccccttcac
    10261 gctcgactgg ttccgcggcg gcaacgcccg cctggtccgc aacgaccggt ggtacggcgg
    10321 tgaggtgcac ctcgacgcca tcgaggtgag gatcttcgag agcccacagg cgatggcgag
    10381 cgcgctgctg gccggccaga tcgacctcgc ctccaacgtc ggcgccgtcg cggcccgcac
    10441 ggccaagggg cgcggggaca tccagaccgt ccgccgcccc aacgacatgg ccatgcccct
    10501 cgtcctgcgc accgccgacg gccccttcgc cgacccgaag gtccgcgagg cgctccgcct
    10561 ggccgtcgac cgcgaggcca tggtcaagca ggtcctgtcc ggctacggca gcgtcgccaa
    10621 cgacgtcctc ggcaccggcg accccgccta cgccaaggac ctcccgcagc gcacccgcga
    10681 cctggcccgc gccaggaagc tgctgaagga ggccggcttc gacacctcca agacgtacga
    10741 actccgcacc accgaggaca tctccggcct cgccgagtcc gccaccctct tcgcctccca
    10801 ggtccgcgag gccggcgtga agatcaaggt ggtcaagcag gagtcggccg tcttctggga
    10861 caagacctgg ctcaaggccg acctctacac cacctactgg ggcaccaacg actcggtggt
    10921 cttcttcgcc agcaagacca tggtctccga cagcgcccag aacgaggccg gcttcaagga
    10981 ccgcgcgttc gacgtggcct accggaaggc catcggcacc gccgacgcca ccgagcgcgc
    11041 gcggctgctg aaggaactcc agcggatcga gtacgaacgc tccggctacc tgctgtgggg
    11101 catggccgac ggtatcgacc tcgccgggtc cgccgtccgc ggcctgccca cgctgcccgg
    11161 gtacgggcgg gtccagctcg aacaggcatg gctggcccgt tgacggccgg caccgccgcg
    11221 ccggccctgg gcgagggggc ggcgccgcca cgtgtcctga ggcacctcgc ccgcctcggc
    11281 gcgctgctgc tcaagcgcgc ggcactgctg gccaccctgc tggcgctggt cttcgtcacc
    11341 atcgaactgc tgcccggcga cgcggcgacc gccacctccg agcgcggcga gagcgcggcc
    11401 gacgtcgccc gccggcgcgc cctgctcggc ctggaccggc cgctgcccac ccgcttctgg
    11461 gactggatgt ccggcctgcc caccggcgac ctcggcacct cggcccgcgg cgaacgcgtc
    11521 accgacctga tctccaccgc gttccccaac accctgctgc tcggcggcat cgccctgctc
    11581 ctcaccgccg tcctctcgct ggccctgggc tgctgggccg cgctgcgccc gggcggccgg
    11641 ctggaccggg cggtgtcggg cacggcgacg gcggtgctcg ccctgcccga gttcgtggtc
    11701 gcggtcgccc tcgtgctcgt gctctcgctg tggaccggct ggctgcccgc cgtcaccctc
    11761 accgacgccg acggaaaccc cgcctcgtgg acgatgctga tcctgcccgc cctcgccctg
    11821 accgtcccgc agaccggctg gaacacccgc atcgtgcgcg ccgccctcgc cgacgaggcc
    11881 cgcgcaccgc acgtggagac cgctctcctg gacggactcc cgccgcaccg cgtgctgacc
    11941 caccacgtcc tgcccggcgc cctgcccacc atcgcggcgg gcctggccac ctccaccggc
    12001 atgctgctgg gcggcgccgt cgtggtcgag acgatcttca actaccccgg tgtcggcgcg
    12061 gtcctggcct ccgccgtcac cgaccgcgac acccccgtca tcgccggcgt cacggccctg
    12121 tccggcgcgg tcatcaccgg ggtgctgctc gcggccgacc tggtgcggga cgccgtggcg
    12181 ggaggccgcc gatgagcccc gacagcacgg cgggacgccc gaccggaaca ccgccctcac
    12241 ccccggcccc gggcaggccc gccccgcgcc tgcgcctgcg gcgcggtccg tcctcgggcc
    12301 acaccccccg gacccctgcc ccgcgccccc gccccggacg gagcccgcgc gccaccgtcc
    12361 tgcggaccct gcccgccctg ctgctgaccg gtctcgcgct cgtcggcccc tggatcgccc
    12421 cccacccggt ggacgccccc cgcaccgcgc cctacgccgg ccccggagcg gacgccgtgc
    12481 tcggcggcga ccagctcggc cgggacgtgc tgagccggct gctggccggc ggccgggaac
    12541 tggtgctctc cgccctgctc gtcgcggtcc tggtcaccgg caccgccgcc gtcctcggcg
    12601 cgatcggggc cgtacgcccg ctcgtcggcc ggctggtgga acggacggcg gacatgctca
    12661 tgctgctgcc ggccgtgctc ggcatcctcc tcgtcaccct ctcctggccc ggcggcggcc
    12721 ggctcgccgt catcgtcgcc gccgtcgtcc taggcgtgcc gtacgcggtc cggctcaccg
    12781 cgggcgccgc ggccccggtc gccgcctccg gctacgtgga ggccgcggcg gcgggcgggg
    12841 aacgcctgtg gtacctcgtc gtccgcgaga tcctgcccaa cctgcgcgcc accctcctcg
    12901 ccctgttcgg cctgcgcttc gtcgccgccg tgtacctcgt cgccacggcc ggcttcctcc
    12961 aggtcggccc gcaacccccc gccgccgact gggcgttgat gatccgcgag aactcctccg
    13021 gcatcctgct caacccctgg gccgtggtcg cccccagcgt cgccatcggc ctgctcgccc
    13081 tgagcgtcaa cctcgccgcg gcgaccctcg tcccgcagac cggccggaag gcggtgaccg
    13141 tcctgtgagc cacgcatccg accggtaccc gaagcatccc gcggtcccgg acgaccaggt
    13201 gccggcggtc cgggtcgacg ccctcaccgt gaccgccgcc gacggccgtc atctgctgca
    13261 cgaggcgtcc ctcaccctcc accccggccg cctggtcgcg ctgaccggcc ggaaggcggt
    13321 gaccgtcctg tgagccacgc atccgaccgg tacccgaagc atcccgcggt cccggacgac
    13381 caggtgccgg cggtccgggt cgacgccctc accgtgaccg gcgccgacgg ccgtcatttg
    13441 ctgcatgagg cgtcgcgcac tctccgc
//
