LOCUS       NZ_AP024135            22445 bp    DNA     linear   CON 08-NOV-2024
DEFINITION  Streptomyces sp. EAS-AB2608 strain NBRC 114648 chromosome.
ACCESSION   NZ_AP024135
VERSION     NZ_AP024135.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. EAS-AB2608
  ORGANISM  Streptomyces sp. EAS-AB2608
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Kitasatosporales; Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Okubo,S., Ena,E., Okuda,A., Kozone,I., Hashimoto,J., Nishitsuji,Y.,
            Fujie,M., Satoh,N., Ikeda,H. and Shin-Ya,K.
  TITLE     Identification of functional cytochrome P450 and ferredoxin from
            Streptomyces sp. EAS-AB2608 by transcriptional analysis and their
            heterologous expression
  JOURNAL   Appl Microbiol Biotechnol 105 (10), 4177-4187 (2021)
   PUBMED   33944982
  REMARK    DOI:10.1007/s00253-021-11304-z
REFERENCE   2  (bases 1 to 9320785)
  AUTHORS   Okubo,S., Ena,E., Okuda,A., Kozone,I., Hashimoto,J., Nishitsuji,Y.,
            Fujie,M., Satoh,N., Ikeda,H. and Shinya,K.
  TITLE     Direct Submission
  JOURNAL   Submitted (28-OCT-2020) Contact:Shinya Okubo Eisai Co., Ltd.;
            Tokodai 5-1-3, Tsukuba 300-2635, Japan
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Newbler v. 2.9
            Genome Coverage                   :: 53x
            Sequencing Technology             :: Miseq; PacBio RS II
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_019703895.1-RS_2024_11_06
            Annotation Date                   :: 11/06/2024 09:16:33
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,174
            CDSs (total)                      :: 8,084
            Genes (coding)                    :: 7,890
            CDSs (with protein)               :: 7,890
            Genes (RNA)                       :: 90
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 194
            CDSs (without protein)            :: 194
            Pseudo Genes (ambiguous residues) :: 0 of 194
            Pseudo Genes (frameshifted)       :: 87 of 194
            Pseudo Genes (incomplete)         :: 132 of 194
            Pseudo Genes (internal stop)      :: 10 of 194
            Pseudo Genes (multiple problems)  :: 32 of 194
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 13:41:52
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 31682
            Orig. end                         :: 54127
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            AP024135.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22445
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RRE-containing"
                     /region_number="2"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     cand_cluster    1..22445
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22445
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12445](+)"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12445
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     gene            220..1938
                     /locus_tag="K6K39_RS00155"
                     /old_locus_tag="EASAB2608_00032"
     CDS             220..1938
                     /GO_function="GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007386765.1"
                     /locus_tag="K6K39_RS00155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EASAB2608_00032"
                     /product="hypothetical protein"
                     /protein_id="WP_059256313.1"
                     /transl_table=11
                     /translation="MRDHDHDHDYDYDLGGHGRRVTTSSPAAQTWFDRGLTWTYAFHHE
                     EAVRCFEAAAAADPGCAMAEWGLAYALGPNYNKPWEFFDAQELRRTAEHAHGAVRRARA
                     KAAGATAVEQALIDALQARYPRATAPDAGEVPVWNAAYADRMRAVHRLAGDDPDVAALY
                     ADALMNLTPWQLWDIRTGRPAAGARTLEAKAVLEQAIAARSGARHPGLLHLYIHLMEMS
                     PTPEAALDVGDRLRGLVPDAGHLQHMPSHLEVLCGDYRRVVSDNNAAIAADEKVRARAG
                     AMNFYTLYRCHNHHFKIYGAMFLGRLQDAVEAAEQLEAAVPEELLRVESPPMADWLEGF
                     AAMRVHVLVRFGRWEDILRLPLPADAQLYCVTTAMLHYARGVALAATGRTREAAREREL
                     FRAAVAQVPETRMLFNNTCRDILAIASHMLDGELEYRAGRYEAAFAALRRSVELDDTLP
                     YDEPWGWMQPTRHAYGALLLEQGRLEQAEAVYRADLGLDDTLPRPLQHPGNVWALHGLH
                     ECLVRLGRQEQAQLVAQQLKFAAALADVRIEASCFCRLKTAADPAGPGGCCEDGH"
     gene            complement(2449..3003)
                     /locus_tag="K6K39_RS00160"
                     /old_locus_tag="EASAB2608_00033"
     CDS             complement(2449..3003)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006122590.1"
                     /locus_tag="K6K39_RS00160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EASAB2608_00033"
                     /product="hypothetical protein"
                     /protein_id="WP_059256310.1"
                     /transl_table=11
                     /translation="MTEPVAQAAPSAEDLLGPALHEEVVAHFTAEVGAPSEATVRHRVR
                     ECLRYLYLVSRHPDRLGGLFLPVEQDIDEIWHYLILQTREYRDLCENRLPGGHFIHHRS
                     ISYDAYQEAPGREAVAEEALRWIPLYTAAFGPFDADALPHWTIVRFLHQELGLSLEEIA
                     ALSEDRPQQEEGTPVPARTDT"
     gene            complement(3102..4331)
                     /locus_tag="K6K39_RS00165"
                     /old_locus_tag="EASAB2608_00034"
     CDS             complement(3102..4331)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006606545.1"
                     /locus_tag="K6K39_RS00165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EASAB2608_00034"
                     /product="hypothetical protein"
                     /protein_id="WP_059256308.1"
                     /transl_table=11
                     /translation="MNRLPSADVLDRVRDIPIYRASIERGHFPILEKPEIARGFPDNWM
                     TPKLKRALEAGEAEFVLSTGTNHARMQLIRPPYFLLRSYYRLWSEHPDLGALWHSGARR
                     VSLTTVLATEHVARVNARRPGTMRGERWLDDRTLYLNRRLDPAGWERDEVERMLAEIRE
                     AAGAHPDGAYLLDCSGYHLAHLVRAVAAWELWDAFPRPAGIVHAYEYTPLNVRAYLRAH
                     FDCPVIDLFGSTELGYLFYSDAHGRYQPYLKDMSVELIPVQPGSGIHSLIVTSVRNPYM
                     PLVRYRSGDCVRTRDNSTDAGQIVSFCGREKELLPTPAGPVAQADLDARIAAVSSRVFL
                     HQLHLAGDDACRLSYTTFDDAPLAPAESSELAAAVSDLTKRSCGLEHRTGIPIGPSGKY
                     AWLTAPAPAV"
     gene            complement(4512..4664)
                     /locus_tag="K6K39_RS00170"
                     /old_locus_tag="EASAB2608_00035"
     CDS             complement(4512..4664)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018956719.1"
                     /locus_tag="K6K39_RS00170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EASAB2608_00035"
                     /product="hypothetical protein"
                     /protein_id="WP_189397482.1"
                     /transl_table=11
                     /translation="MEKLIKRMTEESVWRKWVAVNSAQGAKDGCISAAPKSGCISAAPK
                     SGCIS"
     misc_feature    complement(4758..4773)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 17.53"
                     /tool="antismash"
     gene            4895..5305
                     /locus_tag="K6K39_RS00175"
     CDS             4895..5305
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="K6K39_RS00175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_221333838.1"
                     /transl_table=11
                     /translation="MLPPPDGGAAAVAARRSWWRGGHGGAAAARRGAAVRRWRRGGGAA
                     RRCGGGGAVAARRGGAAVAARWRRGAAVRRWRRGGGAARRCCGGAAVAVARRSWWRGGG
                     AVVVWWRRGGLGGAAAVGGSPGAGGGGRGQVS"
     gene            complement(5505..6905)
                     /locus_tag="K6K39_RS00180"
                     /old_locus_tag="EASAB2608_00036"
     CDS             complement(5505..6905)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007827235.1"
                     /locus_tag="K6K39_RS00180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EASAB2608_00036"
                     /product="DUF11 domain-containing protein"
                     /protein_id="WP_059256306.1"
                     /transl_table=11
                     /translation="MSTPVPPLRVALVNGSFEQPAVTGYEILPDASQTQAPKRVVGWLT
                     TASDHMIELWRSGFNGVPAAEGAQFAELNANEVATLYQDLPTTPGSTLYWRLYHRGRLG
                     QDTMALDIGAPGSPVEQRRFTDGNTAWGYYTGTYTVPEGQHTTRFAFRSVSAAGGNRGI
                     GNFLDGIFFGTAPHLVLTKTAAPAGPLEVGDVITYRINARNEGGGNAENLVLKDTVPQG
                     TTYLPGSLRVLDGPNTGAKSDAQGDDQAYYDAGADQVVFHLGDNASAAQGGSLPSTETL
                     PAGTTVEYRVVIDRASGGRQIRNSATASYENRLGERPELLTAVSGEQVTEVGPAADLSV
                     VKAADATTVTVGQTVTYRVTVINTGPNHATGVTVADPLPEGLVFLSAEAASGAYDPAAG
                     QWAVGDLAEGAGVSLTLRAKATRPGPVTNTATVTGNEKDPGPAPDTDTVTVCVEAAPSC
                     CDPCSPRT"
     gene            8673..>9287
                     /locus_tag="K6K39_RS40645"
                     /pseudo=""
     CDS             8673..>9287
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lant_dehydr_C"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:TIGR03891.1"
                     /locus_tag="K6K39_RS40645"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="thiopeptide-type bacteriocin biosynthesis
                     protein"
                     /pseudo=""
                     /sec_met_domain="Lant_dehydr_C (E-value: 3.8e-10, bitscore:
                     38.7, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIPVERLLADCLDDARTQPLGTVPVSAEDPGYPAARRTFLTAGLQ
                     ALRTHPCETGWVQLNLARHPSRTGPPPYHRLATTARELLTSGQASNFFFMHKPPGLRVR
                     FQAADPDQTAHLREELLRRLDPAPGQDPWTPPTPGVYEPETYLFGGPASMPWVHALFTA
                     DSLAWLDLHTHHAGTPPPPAWRLSLTLLHTVFTALHITGWEH"
     gene            10001..12445
                     /locus_tag="K6K39_RS00190"
                     /old_locus_tag="EASAB2608_00038"
     CDS             10001..12445
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Lanthipeptide_LanB_RRE"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="K6K39_RS00190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="EASAB2608_00038"
                     /product="lantibiotic dehydratase family protein"
                     /protein_id="WP_260334981.1"
                     /sec_met_domain="Lanthipeptide_LanB_RRE (E-value: 9.2e-10,
                     bitscore: 38.0, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPVDLARQARALLHDTQAAQAEENALRQAIAAETERLAQQAWHIT
                     CTNPVMQAFLDSTAPQLIDDIARRLADGQTWSSKQLRKRAAYLWRVIGRAAAKTTPRDW
                     AGQTALIPITNHPTTHHPTLLAPGTPLGDLAAIAVENVHLARARTTPTDLHTATPDTLL
                     APTPLHFTEPPTTRHHTPGHIRCYVIDPTDNSHLRQILLRRTPLLESVLTLLADGPRPL
                     HELEQHLAPHTPPPDQPPLTPEVLRGFLQHLHRLGVLQICRPPRHHVITWTPTTTITTA
                     SPQAPASEGPGAPPEAPASDGTGTPPQTPADDGTSTPPQPPARSRTRTLPRAPADGGPG
                     AWFLDAYRRLGPGACVPQAAVARVQHGLRIAARIAALRETDQLTDPPPQHPALAALTEQ
                     PRPIGEILAAHLNTDDPPPAPRRYTGWSPARDPAGGYARLLNHLDTAARHGTPCVDLDD
                     TLLDTFGAPPANDALPPWPIDCLLRPLPPPATGTGPLAVLETASAAAVLDARFADALHT
                     LHGSYPNTDAYRAFLTTVETHTAVRFVDLLVPPLTEHAANAVRRPVTTRWWTGDPDPTP
                     YYGTPHPPARHLPLNRITLRRSQNQIVAEADGHRIIPVYHATRSPAPPYDTLLRLLLAA
                     SHPAASYLLRLDTLDTALPHHTRLPRLTAGNALVLAPATWHIDRTRLWHPRDDPLTKIR
                     TLALLRRTNHLPAHTFARTAPATKPIPLDLTSLTAIPHIERLCAQHTTPTLQLEEMLPA
                     PGQHLLHDPLHHNATLATQLLLRLPHQPPTTAPPPHNVPGPAHPADHRDEPHPTKPKRR
                     NP"
     aSDomain        10553..10786
                     /aSDomain="Lanthipeptide_LanB_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing LanB protein in a class I
                     lanthipeptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_K6K39_RS00190_Lanthipeptide_LanB_RRE.
                     1"
                     /evalue="3.20E-12"
                     /identifier="RREFam001.1"
                     /label="K6K39_RS00190"
                     /locus_tag="K6K39_RS00190"
                     /protein_end="262"
                     /protein_start="184"
                     /score="38.0"
                     /tool="antismash"
                     /translation="RCYVIDPTDNSHLRQILLRRTPLLESVLTLLADGPRPLHELEQHL
                     APHTPPPDQPPLTPEVLRGFLQHLHRLGVLQIC"
     gene            12442..12594
                     /locus_tag="K6K39_RS00195"
                     /old_locus_tag="EASAB2608_00039"
     CDS             12442..12594
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018569785.1"
                     /locus_tag="K6K39_RS00195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EASAB2608_00039"
                     /product="hypothetical protein"
                     /protein_id="WP_189396911.1"
                     /transl_table=11
                     /translation="MNHNEATELDTLINDLEERITHDDLPATAAYTEGCSGLCTIVICG
                     TVVIC"
     misc_feature    12860..12875
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 21.14"
                     /tool="antismash"
     gene            13072..13476
                     /locus_tag="K6K39_RS00200"
                     /old_locus_tag="EASAB2608_00041"
     CDS             13072..13476
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="K6K39_RS00200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="EASAB2608_00041"
                     /product="hypothetical protein"
                     /protein_id="WP_221333839.1"
                     /transl_table=11
                     /translation="MWTVIDAAASFPTHVFTAALLVVVCFWLVVAAGVADSACFDEDID
                     GDAWGLGGIPVAASFSLMMAFAWTGSLCAALLTGPLGASWVLTALASGVVLAGAPLLAW
                     WLTRALVRLLRRRHPDEHAPSAYLPGSPLT"
     gene            13563..15596
                     /locus_tag="K6K39_RS00205"
                     /old_locus_tag="EASAB2608_00042"
     CDS             13563..15596
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020133851.1"
                     /locus_tag="K6K39_RS00205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EASAB2608_00042"
                     /product="hypothetical protein"
                     /protein_id="WP_086700116.1"
                     /transl_table=11
                     /translation="MNAIAVGIGVCLLIAVVLLLVVSRLFRKVEQGKALIVSKLRKVDV
                     TFTGQVVLPVLHKAEVMDISVKTIEITRAGKDGLICKDNIRADIRISFFVKVNKTVEDV
                     IKVAQAVGTQRASDRDTLQELFHAKFSEALKTVGKQLDFTDLYTKREELRYRIIEVIGV
                     DLNGYHLEDAAIDYLEQTPLTQLDPANVLDAQGIRKITELTAVEHVRTNEAQRNEEKEI
                     TRQNVDAREAVLELERRQADAEIKQRREIETVRAREEAETARVVEEERLRAQSAFLRTE
                     EQLGVQRENQAREVAVAQKNRERVIAVENERIEKDRLLEAIARERETQLTRIAAEKEVE
                     AEKRDIAEVIRERVAVDRTVAEQEESIKKLRAVEEAERQRQTVVIAAEAEAQEKLVKDI
                     KAAEAAEQAAVHRAAEELTLAEARLKSADLDAQAKARLAEGIRAEAAAEGLATVQVRDK
                     EAEVIEKAGRAQAEATQARMLAEAEGVKARALAEAEAIGEKLKAEAAGLTEKAAAMAAL
                     DEASRTHEEYRLRLEAEKDIRLAGLDVQRQVAEAQATVLATGLEKADISIVGGESVFFD
                     RLVNSIALGKGIDGFVEHSATAQALAKPWLDGTSGFTDDLTRVLGSLSTGDVQNLTVSA
                     LLMKLMKTGGAHAGQLRQLLDKAGELGLADTPLAAVNGSARG"
     gene            15673..20568
                     /locus_tag="K6K39_RS00210"
                     /old_locus_tag="EASAB2608_00043"
     CDS             15673..20568
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018569073.1"
                     /locus_tag="K6K39_RS00210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EASAB2608_00043"
                     /product="DNA repair ATPase"
                     /protein_id="WP_221333840.1"
                     /transl_table=11
                     /translation="MTTGLDTGLYDAVDTGTYEVLRDRLTAQAAELARRAEALNARRTE
                     EFGSTRLDLTGSGRLRSEHAGIARDVVAVGDRLLFGRDAASGLRAEPAVGDVLALYDRD
                     LNRLPEDAVPGLLDDPAFRREFAALFRYFRQARLLGLRRVEGRLLAVFRTGEKAGDVRV
                     LRWSVADDGSVSFLDARGDRDDVLPPSHDFTWTRATREDHVPGAHRPHVRVGGEILVSA
                     VGGALTVRAEAEDDDLFTEPVDEPLQSLADADIAHARVGVLVLLRVRPYKEDAHRYLVF
                     NTLTRTVVRLDALGQACRRLPDDQGIVFPGGYCLATGTYKIFDIDHGGLEFETEVRSPY
                     GEDVLYVFHARAQGRGLLLSYNTIRKEVAAPLVCRGWALFEDGVLAVLRADGDEPARVH
                     PLQLWTSPYVSDTYAAARPVGEGPLARIGNADLVRGIADCLAVTRAVAETTPTSEVYAA
                     LVTGCARTADAHHWLGEPDLGDLLEPLQQVRDTAEQVLAEFATVRTLTRRAAEALAEAA
                     GRLAAVVRRLRGEAPREAGAWVTGLTELRRAQGHLLTLKDLRYADTARIDALAAEAEAD
                     LAAFGQRAMTYLGRADAFAAHRREVDQLAADAEALTALAQAAPVEARLDRLADSLHTVT
                     EVVSGLDIADATVRTSVLERIAEVLGGANRVRAILDVRRHDLRDSEGRAEFAAELTLLG
                     QTVTGALAAADTPDACDDRLARVLAQVDTLESRFAEFEDFVGELAGRRTEVYEAFAARK
                     QALVDARARRAEQLAASAQRVLETIVRRVLTLADADAVSTCFASDPMVAKVRRTADELR
                     ALGDGVRAEELDGRLKAARQEALRSLRDRADLFGDGGRTIRLGGHRFAVSTEPFDLTLV
                     PYGDGLAFAVTGTDYRAPVTDPGFADTRPYWDRHLPSESPVVYRAEHLAARLLHQHGVE
                     ALSEADLPALVRTAAQESYDEGYERGVHDHDATAILTALLPLYGQAGTLRHEPGTRAVA
                     QMFWAHGTTADQRAAWTRRAVSLARARDAFGLAPAIADLRAELADAIGGDRAPEAAAYL
                     FEELTTGPDGFVLSAGARTLLDKFRRTVGVSAYDEDLVALDDLVARRQLVEGWLSAYVS
                     ATGEDVTAGELAEAVAAELCRDLTRHVSEAALETTVDGLLGSHPRISGRRMRLRVDDFL
                     ARTRHFAGHDVPAFRAYQRRRTALVAAERARLRLDDHRPRPLAAFVRGRLVDEVYLPLV
                     GDSLARQLGTTGGTKRTDTGGLLLLVSPPGYGKTTLMEYVADRLGLMLVKVSGPALGPT
                     VTSLDPAEAPNATARQEIEKINFALAAGNNTLLYLDDIQHTSPELLQKFIPLCDATRRI
                     DGVWDGEPRTYDLRGKRFAVCMAGNPYTESGARFQVPDMLASRADVWNLGDVLTGKEDV
                     FAHSFLENALTSNPVLAPLAGRDPHDLDVFVRLAEGDPTARADHLSHPYAPAEAEQIQA
                     VLRHLLRVRETVLAVNAAYIASAAQTDATRTEPPFRLQGSYRTMNKIAQRIRPVMNDAE
                     VAAVVDDHFTAEAQTLTTGAEASLLKLAELRGTQTSAQAARWAALKAAHVRTQTLGGAE
                     EDPLVRAVAALGLLADRVAAVEAAITRAADPRHPLALADPHARHAARTQEEL"
     misc_feature    complement(20934..20949)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 19.2"
                     /tool="antismash"
     misc_feature    complement(20946..20955)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 13.67"
                     /tool="antismash"
     gene            20975..22027
                     /locus_tag="K6K39_RS00215"
                     /old_locus_tag="EASAB2608_00045"
     CDS             20975..22027
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005484236.1"
                     /locus_tag="K6K39_RS00215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EASAB2608_00045"
                     /product="CdaR family transcriptional regulator"
                     /protein_id="WP_221333841.1"
                     /transl_table=11
                     /translation="MAERDVPEEYLEGYARILADASATGRRLTRDELDSRRALGEQAAE
                     AGFGLRALVGAHLAATRTHWPARKGACADTIMAAAAQALDAFAEGYERAQRHAVRQEEA
                     ARREFIDDLLYGRSDLGRLAQRAERYGLRLSTAHAVAVARGEAAYDEGDVVPQDVERAL
                     IARFGDRSILLTTKDGRLVCIAPGDQDEVLAFFAKQAYAATNGGRVAIGRPQPGAAGVV
                     QSYEEALNTLDLADRLELDEPVLRAADLLVYPVLARDRQAMTDLVASVLGPLQRARGGA
                     EPLLETLTAYFDAGCVATVAARRLSLSVRAFTYRLERIHKLTGADPSDPVHRYTLQTAV
                     IGARLLGWPT"
     gene            complement(22024..22259)
                     /locus_tag="K6K39_RS41880"
                     /old_locus_tag="EASAB2608_00046"
                     /pseudo=""
     CDS             complement(22024..22259)
                     /GO_process="GO:0015031 - protein transport [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004985337.1"
                     /locus_tag="K6K39_RS41880"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="EASAB2608_00046"
                     /product="twin-arginine translocase TatA/TatE family
                     subunit"
                     /pseudo=""
                     /transl_table=11
                     /translation="MFGLSELAIILIVVIAVLAAKKLPELARSAGKSARILKAETKTTN
                     EDSGPSTRT"
ORIGIN
        1 gcaccgtccg tccggagggc gccggccagg ggcgccggac gggggcccgt gcggggcatg
       61 cctgcgggcc cgtcgtacgg ggcacccgtg cgggggccgc cccgcacgac gggccggtgt
      121 cctggccgac cgttcgctag ggtcgtgaca ccggcccgcc ctcccgccct gcccgggacg
      181 cccgggacgg cccgccggcc ggccctggaa ggagttccgg tgcgcgacca cgaccacgac
      241 cacgattacg actacgacct cggcggccac ggccggcgcg tgacgacctc gtcccccgcg
      301 gcacagacct ggttcgaccg cgggctgacc tggacctacg ccttccacca cgaggaggcc
      361 gtgcgctgct tcgaggccgc cgccgccgcg gaccccggct gcgccatggc cgagtggggc
      421 ctggcctacg cgctgggccc caactacaac aaaccctggg agttcttcga cgcccaggaa
      481 cttcggcgca ccgcggaaca cgcgcacggc gccgtacggc gcgcccgggc caaagcggcc
      541 ggcgccaccg ccgtcgagca ggccctcatc gacgccctcc aggcccgcta cccgcgggcg
      601 acggccccgg acgccgggga ggtgccggtg tggaacgccg cctacgccga ccgcatgcgc
      661 gccgtgcacc ggctggccgg cgacgacccg gacgtcgccg ccctgtacgc cgacgcgctg
      721 atgaacctca ccccctggca gctgtgggac atccgcaccg gccggccggc cgcgggcgcc
      781 cgcaccctgg aggccaaggc cgtcctcgag caggcgatcg ccgcccggtc gggcgcgcgg
      841 cacccgggac tgctgcacct gtacatccac ctgatggaga tgtcaccgac gccggaagcc
      901 gccctggacg tcggtgaccg gctgcgcggt ctggtccccg acgccggcca cctgcagcac
      961 atgccgtcgc acctggaggt gctgtgcggc gactaccgcc gggtggtcag cgacaacaac
     1021 gcggcgatcg cggccgacga gaaagtgcgc gcccgggccg gggcgatgaa cttctacacc
     1081 ctctaccggt gccacaacca ccacttcaag atctacggcg cgatgttcct cggccgcctc
     1141 caggacgccg tcgaggccgc cgaacagctg gaggcggccg tgcccgagga actgctgcgc
     1201 gtggagagcc cgcccatggc ggactggctg gagggctttg cggccatgcg ggtgcacgtg
     1261 ctggtccgct tcggccgctg ggaggacatc ctgcgcctgc cgctgcccgc cgacgcacag
     1321 ctgtactgcg tgaccacggc gatgctgcac tacgcccgcg gggtcgcgct cgccgccacc
     1381 ggccgcaccc gcgaggccgc gcgggaacgg gaactgttca gggccgcggt cgcgcaggtc
     1441 cccgagacac ggatgctgtt caacaacacc tgccgggaca tcctggcgat cgcctcccac
     1501 atgctggacg gggaactgga gtaccgggcg ggccggtacg aggcggcgtt cgccgcgctg
     1561 cgccggtcgg tcgagctgga cgacaccctg ccctacgacg agccgtgggg atggatgcag
     1621 cccacccggc acgcctacgg ggcgctgctg ctggaacagg gccgcctgga gcaggccgag
     1681 gccgtctacc gcgccgacct cgggctcgac gacacgctgc cgcgcccgct gcagcacccg
     1741 ggcaacgtct gggcgctgca cggcctgcac gagtgcctcg tccggctcgg caggcaggaa
     1801 caggcgcagc tggtggcgca gcagctgaag ttcgccgcgg cactggcgga cgtacggatc
     1861 gaagcgtcct gcttctgccg gctcaagacc gccgcggacc cggccgggcc cggcggctgc
     1921 tgcgaggacg gacactgaac cccaggagct gccaggtcac ccccccccac cccggccagt
     1981 ccagcccccc cttcgccgcc agggcggccc cccggcagga cggcgcgccc cccgccgcca
     2041 gggcggcccc cggcacgacg gcaccccggc aggacagcgc cccggcacga cggcccccgg
     2101 caggacagcg ccccggcagg acggcgcccc ggcgcggcgg caccccggca ggacggcccc
     2161 cggcaggaca gcgccccggc aggacggccc ctcggcgcgg cggcaccggg caggacggca
     2221 ccccggcagg cggtcccgga cggccgccgg cggcggccgt ccgcggtccg ctgacccggc
     2281 cggcgggcag gccgctgcgc gggccggcgg gagcagcccg cccgcgcacc gggaagacga
     2341 ccgcgccccg cgggccggga agacgaccgc gccccgcggg ccggggtgat gaccgcaccc
     2401 cgcggaccag ggtgccgtcc gtggccggcc ggggggcgtt ggtgtgtgtc aggtgtccgt
     2461 ccgggccggg acgggcgtgc cctcctcctg ctgcggccgg tcctcggaca gggccgcgat
     2521 ctcttccagg gacaggccca gttcctggtg caggaaccgc acgatcgtcc agtgcggcag
     2581 ggcgtcggcg tcgaaggggc cgaacgcggc ggtgtagagg gggatccagc gcagggcctc
     2641 ctcggcgacg gcctcccgcc cgggggcttc ctggtaggcg tcgtaggaga tgctgcggtg
     2701 gtggatgaag tgcccgccgg gcagccggtt ctcgcacagg tcgcggtact cgcgggtctg
     2761 caggatgagg tagtgccaga tctcgtcgat gtcctgctcg accggcagga agaggccgcc
     2821 gagccggtcg gggtggcggg agacgagata gaggtagcgc agacactcgc ggacccggtg
     2881 gcggacggtc gcctccgagg gcgcgcccac ctcggcggtg aagtgggcga cgacttcctc
     2941 gtgcagggcg gggcccagga ggtcctcggc ggagggggcc gcttgggcca cgggctcggt
     3001 catgggtgcg ggtgtggtca tcgccggtcc tgtcgggtcg tcaggtgtgc tgcgtgtcgg
     3061 gtggcggatc gtcaggcggg tgccgcgggc tgcccggggc gtcagacggc cggcgcaggg
     3121 gcggtcagcc aggcgtactt cccggacggg ccgatgggga tgccggtgcg gtgctcgaga
     3181 ccgcaggagc gtttcgtcag gtcgctgacg gcggcggcca gttcgctgct ctcggcggga
     3241 gcgagggggg cgtcgtcgaa agtggtgtac gacagccggc acgcgtcgtc accggcgagg
     3301 tggagctggt gcaggaagac gcgggagctg accgcggcga tgcgggcgtc gaggtcggcc
     3361 tgggcgacgg gaccggccgg ggtgggcagc agttccttct cccgtccgca gaaggagacg
     3421 atctgcccgg cgtcggtgct gttgtcgcgg gtgcgcacgc agtcgccgga gcggtagcgc
     3481 accagcggca tgtaggggtt gcggacactg gtgacgatga ggctgtggat gccgctgccc
     3541 ggctgcaccg ggatcagttc cacgctcatg tccttcaggt agggctggta gcggccgtgc
     3601 gcatcgctgt agaagaggta gccgagctcg gtgctgccga acaggtcgat gacggggcag
     3661 tcgaaatggg cacgcagata ggcgcggacg ttgagcggcg tgtactcgta ggcgtggacg
     3721 atgccggccg ggcgggggaa ggcgtcccac agctcccagg ccgccacggc gcggaccagg
     3781 tgcgccaggt ggtagccgga gcagtccagc aggtaggcgc cgtcggggtg ggcgccggcc
     3841 gcttcgcgga tctcggcgag catacgctcg acctcgtcgc gttcccagcc ggccgggtcc
     3901 agacggcggt tgaggtagag cgtacggtcg tccagccagc gttcgccccg catcgtgccg
     3961 ggcctgcggg cattgacacg ggcgacgtgc tcggtggcca gcaccgtggt cagcgacacc
     4021 cgccgggccc cggagtgcca cagggcaccg aggtcagggt gctcgctcca cagacggtag
     4081 taggaacgca gcaggaagta aggcggccgg atgagctgca tgcgggcatg gttggtgccg
     4141 gtggacagca cgaactccgc ctctcccgcc tcaagtgcac gcttgagttt cggagtcatc
     4201 cagttgtcgg ggaagccccg ggcgatctcc ggcttctcca ggatcgggaa gtgaccgcgc
     4261 tcgatggagg cacggtagat cggtatgtcg cgcacccggt ccaggacgtc ggcgctcggc
     4321 aggcggttca caagggctct ccggaacggc aggaaaaaac gggggcggcg gagacggaac
     4381 ggggacggag acggaagaag acgacggcgg cggaagaaga cggcggcggc ggataaggag
     4441 gagcgggggc gggggtacgg agggacacgc ggggcccctc cgcaccaccg gcccgcggcg
     4501 tcagcggatg gtcaggagat acagccgctc ttgggcgcgg cgctgatgca gccgctcttg
     4561 ggcgcggcgc tgatgcagcc gtccttcgca ccctgagccg agttgacggc gacccacttg
     4621 cgccacacgg actcctcggt catgcgcttg atgagcttct ccatagtgaa acctccaggc
     4681 gtggacgcaa tctggcattt ggtcaggtgc agatgggttt gcgtcggtca cccaccggca
     4741 ccgaacgtaa agagatggtc aaccacacgt caagaggtaa atgatcagat gacctgatct
     4801 gcaccctcgg cgggggcggc cggaccggtt ccgggctggt accgcagggc gcccacgccc
     4861 gctgccggga cccgccacgc gcggcagcgc cacaatgctg ccgccgcccg acggcggcgc
     4921 ggcggcggtg gcggcgcggc ggtcctggtg gcgcggcggt catggtggcg cggcggcggc
     4981 gcggcgcggc gcggcggtgc ggcggtggcg gcgcggtggc ggcgcggcgc ggcggtgcgg
     5041 cggtggcggc gcggtggcgg cgcggcgcgg cggtgcggcg gtggcggcgc ggtggcggcg
     5101 cggcgcggcg gtgcggcggt ggcggcgcgg tggcggcgcg gcgcggcggt gctgcggtgg
     5161 cgcggcggtg gcggtggcgc ggcggtcatg gtggcgcggc ggcggcgcgg tggtggtgtg
     5221 gtggcggcgc ggcggtcttg gtggtgcggc ggcggtgggc ggttcgccgg gtgccggggg
     5281 cggcgggcgc gggcaggtgt cttgaaaccg gcccgggcgg gcacggcgcc gacggcggca
     5341 ggccccgggc cggtgaccgg tccggggcct ggccgccgca cgcgggcacg agaggtaccg
     5401 gggcgcggcg gcgaggggcg aagggcgcga aaagacgggt catgaggggg cgaagggggc
     5461 gggacggggc agggcgggag ggggcagggc gggcagggcg ggggtcaggt ccggggggag
     5521 caggggtcgc agcaggaggg ggccgcctcg acgcagacgg tgaccgtgtc ggtgtcgggg
     5581 gcggggccgg ggtccttctc gttgccggtg acggtggcgg tgttggtcac cgggccgggc
     5641 cgggtggcct tggcccgcag ggtgagggac acgccggcgc cctcggcgag gtcgcccacc
     5701 gcccactgcc cggcagccgg gtcgtaggcg ccagaggctg cctcggcgga caggaagacc
     5761 agaccctcag gaagcgggtc ggcgacagtg acgccggtag cgtggttcgg accggtgttg
     5821 atgacggtga cgcggtaagt gacggtctga ccgacagtga cggtggtcgc gtccgccgcc
     5881 ttcaccacac tcaggtccgc cgccggcccg acctcagtga cctgctcccc ggaaacagcc
     5941 gtcaacaact caggccgctc gccgagccgg ttctcatagg aagcagtggc actgttcctg
     6001 atctgcctac ccccgctcgc ccggtcgatg acgacccggt actccaccgt ggtgcccgcc
     6061 ggcagcgtct cggtgctggg cagactgcct ccctgcgccg cggaggcgtt gtcgcccagg
     6121 tggaagacga cctggtccgc cccggcgtcg tagtaggcct ggtcgtcgcc ctgcgcgtcg
     6181 ctcttggccc cggtgttcgg accgtccagc actcgcaggg accccggcag atacgtcgtg
     6241 ccctgcggga cggtgtcctt gaggacgagg ttctccgcgt tgccgccgcc ctcgttcctg
     6301 gcgttgatgc ggtaggtgat gacgtcaccg acctccagcg gccccgcggg agcggcggtc
     6361 ttggtcagca ccaggtgggg agcggtgccg aagaagatgc cgtcgaggaa gttgccgatg
     6421 ccgcggttgc cgccggcggc ggagacggac cggaaggcga agcgggtggt gtgctgcccc
     6481 tcggggacgg tgtaggtgcc ggtgtagtag ccccacgcgg tgttgccgtc ggtgaagcgc
     6541 cgctgctcca ccggggagcc gggggcaccg atgtccaggg ccatggtgtc ctgccccagc
     6601 cggccacggt ggtagagccg ccagtacagg gtcgaaccgg gcgtggtcgg cagatcctgg
     6661 tagagcgtgg cgacctcgtt ggcgttgagt tcggcgaact gggcgccctc ggcggccggc
     6721 acaccgttga accccgaccg ccacagttcg atcatgtggt cggacgcggt ggtgagccag
     6781 cccacgaccc gcttgggcgc ctgggtctgc gaggcgtccg gcaggatctc gtaaccggtg
     6841 acggcgggct gctcgaaact gccgttgacc agggccaccc tgagcggcgg tacgggtgtg
     6901 ctcatcggtc ttccccctca cgtcgaggat gcggaaggct ccgccaccgg ccgggttcgg
     6961 ccgggccggt gagggagccg ggaacacccg acagcccagc gcatgcccgc acagcacgga
     7021 aagggacggc cgggcaggtc aggccaaccc cgcacggcgg gtttcatccg ccctcccccg
     7081 gacgcccctt gccgccccgg cagccacggc cacgcagcgg acaccacatg cgccgcacat
     7141 gtgccaatgg catctgccgc cgcacacacc acgaccgaaa gcgacccgcc accgctcccc
     7201 cactcaccct cccagcgggt gaaccagcga acgcccagtt gacgcccccg tacgcccggc
     7261 ccgacctacc cgccccccac ggcgacccgc cgcggccccc ggggccggga accggcggcc
     7321 ggcggccggg gaccggggcg gcggcgggtc ccccttccct ccccgcgtgc ggccggtcgg
     7381 gaggccaggg gagcgccggc cacggtccag gcacccggca gcgcctgccc acgcacaccc
     7441 ccgacccccg gaccacccgc ctcccccgcc gcccccgcgc gccggcacgg tgaaccagcc
     7501 cggccacacc tcgacgacca gcggcatcaa cgactccaca gccgcacgca gatcctttgt
     7561 gacggcatcc accggcccgg gcaggccctg cctctcacag cgcagccgcc acaaaccgaa
     7621 gccccccgcc ccgccggccg tgaagcccac cacgacgact gccgcccccg gccgtgaacc
     7681 gccagcccac cccgtgcacc cggcagcagc aaccgccggc cccgtcgctc cggctgaccc
     7741 ggcccgaaca ggcgagcccg agcacgtcca ccagccgcac cagcccgggc aacgcccccg
     7801 caccacctca ccgccaacac ccagcgcgcc cacataaccg aacagcaact cccgcccaca
     7861 aacacacgaa cccacccacg acccaaggcc cgccctcccg cctcacgccg tccccccctc
     7921 tgcgccgaca tcagggccgc ccactgccca ccacagccgc ccgcgccctc cgcgcccatc
     7981 cgcgccgacc gcgcgtccgc ggcgcgcccg atcacacagc agcgacggca ccagccgcac
     8041 cccgctcccc ggctcccctc gctcggcccc cacccgagac gagccgcgga cacatccctg
     8101 cccgcccaca gcacacccgc cccggatccc gcaccccgcc ggtctccccg gccaggaccc
     8161 cgtcaccggc cggcacaggt gcaaggtgcc ggtgccggcc cggcaacctg caccagcacc
     8221 ggaccagggc cagcaccggg accgaggcca gcaccagagc cggtgggcca gcaccagagc
     8281 gggggggcca gcaccgggac cgaggccagc cccagggcgg gggccaacac cgagaccaga
     8341 accaggacca gcaccaaggc gggcggccag caccagcacc ggggccaggg ccagggcggg
     8401 ggccaacacc gggaccagaa ccggggccag caccagggcc aaggcgggga gccagcatcg
     8461 ggaccagagc caacgccagg gcgagggacg gggcgggggc cggctgggcg gcgccggtgg
     8521 gagaccggcg cgccggccgg gctttcacgg caggcggcat acctcccgcg cactcctgtt
     8581 gatcatatga ccaatccatt gtcgtgcttc ggaacaccgg cggcccggac atcacacagg
     8641 tggcgtccgt cttcaacgcc tgaggagacc gcatgatccc ggtggagcgt ctgctggccg
     8701 actgcctgga cgacgcacgt acccagccgc tgggcaccgt cccggtctca gccgaggacc
     8761 ccggctaccc ggcagcccgc cgcaccttcc tgaccgccgg cctgcaagcc ctgcgcaccc
     8821 acccgtgcga gaccggatgg gtacagctca acctcgcccg ccacccctcc cgaaccggcc
     8881 cgccgcccta ccaccggctc gccaccaccg cccgagaact cctcaccagc ggacaggcca
     8941 gcaacttctt cttcatgcac aaaccccccg gcctgcgcgt gcggttccag gcagccgacc
     9001 ccgaccagac agcacacctg cgcgaagaac tgctacgccg cctggacccg gcacccggac
     9061 aagacccctg gaccccgccc acgcccggcg tgtacgaacc cgaaacctac ctcttcggcg
     9121 gcccggcctc catgccctgg gtccacgcac tgttcaccgc cgactccctt gcctggctcg
     9181 acctccacac acaccacgcc ggcactcccc caccccccgc ctggcgcctg tccctgaccc
     9241 tgctccacac cgtgttcacc gccctgcaca tcaccggctg ggaacaccgc ggagtctggc
     9301 agaccgtcaa agaagaaacc ggccgccgcc tcccaggcgg actcaacacg cccgaccgcc
     9361 gacgcgccgc cgccggaatc cgcgcctggt gggaacaaac ccccaccacc cgcctccaca
     9421 cactcccccc ccgcctggca ccacaccatc accacacaca cccagacagc cgaacaagcc
     9481 gcacaacact ggcacaccca ctacttcacc accacccaag ccaccaccgg cccccgccgc
     9541 gccgccgccc accacgtcat cttccactgg aaccgagccg cactccccac caccacccaa
     9601 tgcctcctca ccgaagcact cgccaccacc acccacgacc acgaagacac acaccaacca
     9661 tgacccacac accacaacaa acccacccaa tcacacccca caaccagaac accccacacc
     9721 caccagccac cacagcactc ctacgcatca gcggcatacc cacccaaacc tggaccacca
     9781 gctccacccc ccacctcttc caacgcgccg caacacacac cgacaccacc acacacctca
     9841 gccaacaagc cagacacctc gccgaccaac tcacccaccg cgtcctatcc cacccccacc
     9901 tacccccacc caccaccccc tcctcgccct gcgccgccgc ctccacgccg gcaccgcccc
     9961 ccgccaccgg gactgcaccc tgctggaaca ctcacccgcc gtgcccgtcg acctcgcccg
    10021 ccaagcccgc gccctgctcc acgacaccca agcagcacag gccgaagaga acgcactacg
    10081 tcaggccatc gcagccgaaa ccgaacgcct cgcccaacag gcctggcaca tcacctgcac
    10141 caacccggtc atgcaggctt tcctcgacag caccgccccg caactcatcg acgacatcgc
    10201 ccgtcggctc gccgacggac agacctggtc aagcaagcaa ctccgcaaac gcgccgccta
    10261 cctatggcgc gtgatcggcc gcgccgcagc caaaaccaca ccccgcgact gggcagggca
    10321 aaccgccctc atccccatca ccaaccaccc caccacacac caccccacgc tccttgcacc
    10381 cggcaccccg ctcggcgacc tcgccgcgat cgccgtggag aacgtccacc tcgcccgggc
    10441 ccgcaccacc cccaccgacc tgcacaccgc cacccccgac accctcctcg cccccacccc
    10501 cctgcacttc accgaaccac ccaccacccg ccaccacacc cccggccaca tccgctgcta
    10561 cgtcatcgac cccaccgaca acagccacct ccgccagatc ctcctgcgcc gcacccccct
    10621 gctggaatcc gtcctcaccc tcctcgccga cggaccacgc cccctgcacg aactcgaaca
    10681 acacctcgcc ccccacaccc caccacccga ccagccaccc ctcacccccg aagtcctccg
    10741 cggattcctg cagcacctcc accgcctggg cgtgctccag atctgccgac ccccccgaca
    10801 ccacgtcatc acctggacac cgaccaccac catcaccacc gcctcgccgc aggcaccagc
    10861 gagcgaggga cccggcgccc cacccgaggc accagcgagc gacggaaccg gcaccccgcc
    10921 acagacaccg gcagacgacg ggaccagcac cccgccccag ccaccggccc gcagccggac
    10981 gcgcaccctg ccacgtgccc cggcggacgg cggccccggg gcctggttcc tcgacgccta
    11041 ccgccgcctc ggccctggcg cctgcgtgcc ccaggcagcc gtcgcacgcg tccagcacgg
    11101 actgcgcatc gcggcccgga tcgccgccct acgcgaaacc gaccagctca ccgacccccc
    11161 accacagcat cccgccctcg ccgcactgac cgaacaacca cgccccatcg gcgagatcct
    11221 cgccgcccac ctgaacaccg acgacccacc ccccgcaccc cgccgctaca ccggctggtc
    11281 ccccgcccgc gatcccgccg gcggctacgc ccgactcctc aatcacctcg acaccgccgc
    11341 ccgccacggc acaccctgcg tcgacctcga cgacacactc ctcgacacct tcggcgcacc
    11401 ccccgccaac gacgccctgc ccccctggcc gatcgactgc ctgctacgcc cattgccccc
    11461 gcccgccacc ggcaccggcc ccctcgccgt cctggaaacc gcctcagccg ccgcagtcct
    11521 cgacgcccgg ttcgccgacg ccctgcacac cctccacggc agctacccca acaccgacgc
    11581 ctaccgcgcc ttcctcacca ccgtcgagac ccacaccgca gtccgcttcg tcgacctgct
    11641 cgtgccaccc ctgaccgaac acgccgccaa cgccgtccgc cgccccgtca ccacccgctg
    11701 gtggaccggc gacccggacc ccacccccta ctacggcaca ccccaccccc cggcccgcca
    11761 cctccccctg aaccgcatca ccctacgccg cagccagaac cagatcgtcg ccgaagcaga
    11821 cggccaccgc atcatccccg tctaccacgc cacccgctcc cccgccccgc cctacgacac
    11881 cctcctacga ctcctcctcg ccgcgagcca ccccgccgcc tcctacctcc tccgcctcga
    11941 cacccttgac acagccctgc cccaccacac ccgactcccc cgactgaccg ccggcaacgc
    12001 cctcgtcctc gcccccgcca cctggcacat cgaccgcacc cgcctctggc acccccgcga
    12061 cgatccgctc accaaaatcc gcaccctcgc cctcctgcgc cgcaccaacc acctccccgc
    12121 ccacaccttc gcccgcaccg cccccgccac caaacccatc cccctcgacc tgacctccct
    12181 caccgccatc cctcacatcg aacgactctg cgcccaacac accaccccca ccctccagct
    12241 cgaagaaatg ctccccgccc ccggccaaca cctcctccac gaccccctcc accacaacgc
    12301 gaccctcgcc acccaactcc tcctccgcct cccccaccaa ccccccacca ccgccccacc
    12361 accccacaac gtccccggac ccgcgcaccc agcggaccac cgggacgaac cccaccccac
    12421 caaacccaaa aggagaaacc catgaaccac aacgaagcca ccgaactcga caccctcatc
    12481 aacgacctcg aagaacgcat cacccacgac gacctccccg ccaccgccgc ctacaccgaa
    12541 ggctgcagcg gcctgtgcac catcgtcatc tgcggcaccg tcgtcatctg ctaacccacc
    12601 ccaaccccac cgagccgccc cccacaaaag gggcggctcg gcccttcccc ccaacacaca
    12661 ccacggtcgc ggctgtcgcc agggggctgc tcctgcgggc cacgcgacgc gagcccgttg
    12721 aaggtacgac cgataccgag ccgctcgccg tcttcgtcag gctggccgtc gggacgatcc
    12781 ccggcgtctt cctcggcgcc tacggagtga ccgctcctac cgcagccgtt cgcttaccgc
    12841 cgcccgttat aaccacgcct tgacgccttc ttgacgctga ccggcatgga gaacccgtca
    12901 aagactgccg gatgtcggca atgcgccgac ggtgtcgctt cggcaggatg aagggcgagg
    12961 ggagcacacg gagtgctctt ggttgccgga cacccgcagg tgtccggcaa ccgagccctg
    13021 ggccgtgcgg ggcagggccg ccatcggacg agcgggatcg ggaggttggg cgtgtggaca
    13081 gtcatcgatg ccgccgcgag ctttccgacc cacgtgttca ctgccgcgct gctcgtggtc
    13141 gtgtgcttct ggctcgtggt cgcggcgggc gtggccgact ccgcctgctt cgacgaggac
    13201 atcgacggtg acgcctgggg cctcggcgga ataccggtcg cggcgtcgtt ctccctgatg
    13261 atggcctttg cctggaccgg cagcctctgt gccgccctcc tgaccggtcc tctcggcgct
    13321 tcgtgggtgc tgaccgccct ggcctccggc gtcgtcctgg ccggcgcccc cttgctcgcg
    13381 tggtggctga cccgagcgct cgtacgcctc ctgcgacgtc gccaccccga cgaacacgcg
    13441 ccgtccgcgt acctgccggg ctccccgctc acttagcgcc gaccgcttcg cccgcctgcc
    13501 ggaacgctgc cacgccgcgc gcccgcctcc atcttgccgt tcacgcccga aggatccttg
    13561 tcatgaatgc catcgccgtg ggcatcggcg tctgcctgct catcgccgtc gtcctgcttc
    13621 tcgtcgtctc ccggctgttc cgcaaggtgg agcagggcaa ggcgctgatc gtctccaagc
    13681 tgcggaaggt cgatgtcacc ttcaccgggc aggtcgtgct gcccgtgctg cacaaggccg
    13741 aggtgatgga catctcggtg aagaccatcg agatcacccg ggccggcaag gacgggctga
    13801 tctgcaagga caacatccgc gcggacatcc gtatctcgtt cttcgtgaag gtcaacaaga
    13861 ccgtcgagga cgtcatcaag gtcgcccagg ccgtcggcac ccagcgggcg agcgaccggg
    13921 acacgcttca ggagctgttc cacgcgaagt tctccgaggc gctgaagacc gtcggcaagc
    13981 agctcgactt caccgacctg tacaccaagc gcgaggagct gcggtaccgg atcatcgagg
    14041 tcatcggcgt cgacctcaac ggctatcacc tggaggacgc ggcgatcgac tacctggagc
    14101 agacgccgct gacccagctc gacccggcca acgtcctcga cgcccagggc atccgcaaga
    14161 tcaccgagtt gacggccgtg gagcacgtac gcaccaacga ggcccagcgc aacgaggaga
    14221 aggagatcac tcggcagaac gtcgacgccc gcgaggccgt gctggagctg gagcggcggc
    14281 aggcggacgc cgagatcaag cagcggcggg agatcgagac ggtccgggcg cgtgaggagg
    14341 ccgagaccgc gcgggtggtc gaggaggagc ggctgcgggc gcagtccgcc ttcctgcgga
    14401 ccgaggaaca gctcggcgtc cagcgggaga accaggcccg ggaggtcgcc gtggcgcaga
    14461 agaaccgcga gcgggtcatc gccgtcgaga acgagcggat cgagaaggac cgtctcctgg
    14521 aggccatcgc acgcgagcgg gagacccagc tgacgcggat cgccgccgag aaggaggtcg
    14581 aggcggagaa gcgggacatc gccgaggtca tccgcgagcg ggtcgccgtg gaccgtacgg
    14641 tcgccgagca ggaggagtcc atcaagaagc tccgtgccgt cgaggaggcc gagcggcagc
    14701 ggcagacggt ggtcatcgcg gccgaggccg aggcgcagga gaagctggtc aaggacatca
    14761 aggccgccga ggccgccgag caggccgccg tgcaccgcgc cgccgaggaa ctcacgctcg
    14821 ccgaagcccg gttgaagagc gccgacctgg acgcgcaggc caaggcgagg ctggccgagg
    14881 gcatccgggc cgaggccgcc gccgaggggc tcgcgacggt ccaggtccgc gacaaggagg
    14941 cggaggtcat cgagaaggcg ggccgggcgc aggccgaggc cacgcaggcg cgcatgctgg
    15001 cggaggccga gggcgtcaag gcgagggcgc tcgcggaggc ggaggccatc ggcgagaagc
    15061 tgaaggcgga ggccgccgga ctcaccgaga aggcggcggc gatggccgcg ctcgacgagg
    15121 cgtcccgcac gcacgaggag taccggctgc ggctggaggc ggagaaggac atccgtctcg
    15181 cgggcctcga cgtgcagcgg caggtcgccg aggcgcaggc cacggtgctg gccaccgggc
    15241 tggagaaggc ggacatcagc atcgtcggcg gggagtcggt cttcttcgac cggctggtga
    15301 actcgatcgc gctcggcaag ggcatcgacg gattcgtcga gcactccgct accgcgcagg
    15361 cactggccaa gccctggctg gacggtacgt cgggtttcac cgatgacctc acccgcgtcc
    15421 tcggttccct ctcgacgggc gacgtccaga acctgaccgt gtccgcgctg ctgatgaagc
    15481 tcatgaagac gggtggcgcg cacgccggac agctgcggca actcctcgac aaggcgggcg
    15541 agctgggtct cgccgacaca ccgctcgccg ccgtgaacgg cagcgcgagg ggatgacagg
    15601 ccggcggttc cggagctgcc gcgcgggggg cggcggctcc ggcccgccac agaacacttc
    15661 cgaggggaac ccatgaccac cggcctggac accggcttgt acgacgccgt cgacaccggc
    15721 acgtacgagg tgctgcgcga ccggctcacc gcgcaggcgg ccgaactggc ccgccgcgcc
    15781 gaggcgctca atgcccgccg taccgaggag ttcggctcca cccggctcga tctgaccggc
    15841 agcggacggc tgcggagcga gcatgccggc atcgcccgcg atgtcgtggc cgtcggggac
    15901 cggctgctgt tcggccgcga cgccgcgtcc ggcctgcgcg cggagccggc cgtcggcgat
    15961 gtcctcgccc tgtacgaccg ggatctgaac cggctgcccg aggacgcggt acccggcctg
    16021 ctcgacgatc cggccttcag gcgggagttc gcggccctgt tccgctactt ccggcaggcc
    16081 cgcctccttg gactgcgccg cgtggagggc aggctgctgg ccgtcttccg gaccggcgag
    16141 aaggccggtg acgtacgggt gctgcgctgg tcggtggcgg acgacgggag cgtgtccttc
    16201 ttggacgcgc gcggcgaccg cgacgatgtg ctcccgccct cccacgactt cacctggacc
    16261 cgggcgacgc gggaggacca cgtcccgggg gcccaccgcc cgcatgtccg ggtcggcggc
    16321 gagatcctcg tctcggccgt cggcggtgcc ctcaccgtcc gtgccgaggc ggaggacgac
    16381 gacctgttca ccgagccggt ggacgaaccg ctccagtccc tcgccgacgc cgacatcgcc
    16441 cacgcgcgcg tgggtgtcct ggtcctgctg cgggtccggc cctacaagga ggacgcccac
    16501 cggtacctgg tgttcaacac actcaccagg acggtcgtcc gtctcgacgc cctggggcag
    16561 gcgtgccgcc gcctccccga cgaccagggc atcgtctttc ccggcggcta ctgcctggcc
    16621 acgggcacgt acaagatctt cgacatcgac cacggcgggc tggagttcga gacggaggtg
    16681 cgttcgccct acggcgagga cgtgctctac gtcttccacg cccgtgcgca gggccgcggg
    16741 ctgctgctgt cgtacaacac catccgcaag gaggtcgcgg ccccgctggt ctgtcggggc
    16801 tgggccctgt tcgaggacgg cgtcctggcg gtgctgcggg cggacggcga cgagcccgcg
    16861 cgcgtgcatc cgctccagct gtggacctcc ccgtacgtct cggacacgta cgccgccgcc
    16921 cgccccgtgg gcgaggggcc gctcgcccgc atcggcaacg ccgacctcgt ccgcggcatc
    16981 gcggactgcc tcgccgtcac cagggccgtg gccgagacca cgccgacgag cgaggtgtac
    17041 gccgcgctcg tcaccggctg cgcccggacc gccgacgcgc accactggtt gggcgagccc
    17101 gacctcggcg acctgctcga accgttgcag caggtgcggg acaccgccga gcaggtgctg
    17161 gccgagttcg cgaccgtgcg gacgctgacg cggcgggccg ccgaggcgct cgccgaggcc
    17221 gccggccggc tcgccgcggt cgtacgccgg ctgcgtggcg aggctccccg cgaggccggc
    17281 gcgtgggtga ccgggctgac cgaactccgc cgtgcgcaag ggcatctgct cacccttaag
    17341 gacctcaggt acgccgacac cgcccggatc gacgcgctgg ccgcggaggc cgaggccgac
    17401 ctcgccgcct tcggtcagcg ggccatgacg tatctgggcc gtgcggacgc ctttgccgcg
    17461 caccggcggg aggtcgatca gctcgccgcc gacgccgagg cgctcaccgc gctggcgcag
    17521 gcggcgccgg tcgaggcgcg gctcgaccgg ctcgcggact cgctgcacac cgtcaccgag
    17581 gtcgtctccg gcctcgacat cgccgacgcc accgtgcgca cgtccgtcct ggagcgcatc
    17641 gccgaggtgc tcggcggcgc caaccgggtg cgggcgatcc tcgacgtccg ccgtcacgat
    17701 ctgcgcgaca gcgaggggcg ggccgagttc gccgccgagc tgaccctgct cggccagacg
    17761 gtcacgggcg cgctcgccgc cgccgatacc ccggacgcgt gcgacgaccg gctggcccgg
    17821 gtgctggccc aggtggacac cctggagtcc cgtttcgcgg agttcgagga cttcgtcggc
    17881 gaactcgccg gccggcgtac cgaggtctac gaggcgttcg ccgcccgcaa gcaggctctc
    17941 gtggatgccc gggcccggcg tgccgaacag ctcgcggcgt ccgcccagcg ggtcctggag
    18001 acgatcgtcc ggcgggtgct gacgctcgcc gacgccgacg cggtcagcac ctgcttcgcc
    18061 tccgacccga tggtcgccaa agtccgccgt accgccgacg aactgcgggc gctcggcgac
    18121 ggggtgcggg cggaggaact ggacggccgg ctgaaggccg cgcgccagga ggcgctgcgc
    18181 tcgctgcgtg accgcgccga cctgttcggg gacgggggac gcacgatccg cctgggcggg
    18241 caccgcttcg ccgtcagtac cgaacccttc gacctcaccc tcgtcccgta cggcgacggc
    18301 ctggcgttcg ccgtcaccgg caccgactac cgcgcccctg tcaccgaccc cggtttcgcg
    18361 gacacacgcc cctactggga ccggcacctg ccctccgagt cacccgtggt ctaccgcgcc
    18421 gagcatctcg ccgcccgcct tctgcaccag cacggcgtcg aggccctgag cgaggcggac
    18481 ctgcccgccc tggtgcgcac ggcggcgcag gagtcgtacg acgaaggcta tgaacgaggc
    18541 gtccacgacc atgacgccac cgcgatcctc accgccctgc tgcctctgta cggacaggcg
    18601 ggaacgctgc gtcacgagcc ggggacgagg gccgtcgccc agatgttctg ggcccacggt
    18661 acgacggccg accagcgtgc ggcgtggacc cggcgcgcgg tgtccctcgc ccgcgcccgc
    18721 gacgccttcg ggctcgcgcc ggcgatcgcc gatctgcggg cggaactcgc ggacgccatc
    18781 ggcggagacc gtgctccaga ggccgccgca tacctcttcg aggagctgac gaccggcccg
    18841 gacggattcg tactgtccgc cggcgcgcgc acgctcctgg acaagttccg ccgcacggtg
    18901 ggtgtttcgg cctatgacga ggacctggtg gcgctggacg acctcgtcgc ccgccgccag
    18961 ctcgtcgaag ggtggctgtc ggcctacgtc tccgccaccg gggaggacgt caccgcgggt
    19021 gagctggccg aggcggtggc agccgagctg tgccgggatc tgacgcgtca tgtgtcggag
    19081 gccgccctgg agacgaccgt ggacggcctg ctcggcagcc acccgcgcat cagcggtcgc
    19141 cgcatgcggc tgcgcgtgga cgacttcctc gcccgcaccc ggcacttcgc cggccatgac
    19201 gtgcccgcct tccgcgccta ccagcgccgg cgcaccgccc tggtggccgc cgagcgggcc
    19261 cggctgcgcc tggacgatca ccgtccgcgc cccctggccg ccttcgtgcg cggcaggctc
    19321 gtcgacgagg tgtatctgcc gctggtcggc gacagcctgg ccaggcagct gggcaccacg
    19381 ggcgggacca agcgcaccga caccggcggc ctgctgctgc tcgtctcacc gcccggctac
    19441 ggcaagacga cactgatgga gtacgtcgcc gaccgcctcg gcctgatgct ggtgaaggtc
    19501 agcggtccgg ctctcggccc caccgtcacc tcgctcgacc cggccgaggc cccgaacgcc
    19561 accgcacgcc aggagatcga gaagatcaac ttcgcgctcg cggccggcaa caacaccttg
    19621 ctgtacctgg acgacatcca gcacacctcc cccgagctgc tgcagaagtt catcccgttg
    19681 tgcgacgcca cccgccggat cgacggtgtg tgggacggcg agccccgcac ctacgacctg
    19741 cgcggcaagc gcttcgccgt ctgcatggcc ggcaacccct acaccgagtc cggcgcccgc
    19801 ttccaggtgc ccgacatgct cgccagccgc gccgacgtgt ggaacctcgg cgacgtcctg
    19861 accggcaagg aggacgtctt cgcccacagc ttcctggaga acgcgctcac ctcgaacccg
    19921 gtgctcgccc cgctcgccgg acgtgacccc cacgacctcg atgtgttcgt ccgcctcgcc
    19981 gagggggacc ccacagcccg cgcggatcac ctctcccacc cctacgcccc tgccgaagcc
    20041 gagcagatac aggccgtgct gcggcatctg ctgcgggtgc gggagacggt gctcgccgtc
    20101 aacgccgcct acatcgcctc cgcggcccag acggacgcca cccgcaccga gccgccgttc
    20161 cggctccagg gctcgtaccg caccatgaac aagatcgctc agcgcatccg gcccgtcatg
    20221 aacgacgccg aggtcgcggc cgtcgtcgac gaccacttca ccgccgaggc ccagaccctg
    20281 accaccggcg ccgaggccag cctgctgaag ctggccgagc ttcgaggcac gcagacttcc
    20341 gcacaggcgg ctcgctgggc cgcgctgaaa gccgcccacg tccgcacgca gaccctcggt
    20401 ggcgccgagg aagaccccct cgtccgtgcc gtcgccgcgc tcggcctgct cgccgaccgc
    20461 gtggctgcgg tggaggccgc catcacgcgc gcggctgatc cgcgccaccc gctcgcgctc
    20521 gccgacccgc atgcccggca cgcggcccga acccaggagg agctgtgacg cccttcctcg
    20581 tccctctcgc cgccgccctg ctgatcgtgg cggcctccac ggtcgtaggt gtacggcggg
    20641 atcggcggcg catggcggcg ggtgtcgagc gcccgcgcac cgagggcgtc acccctctcc
    20701 gtgccgggtg cggcacacgg cacagggcgc cggcgtatga gcacaggtcc cggtgcgagc
    20761 gggagtgacg cgggccggcg ggtcggtaac ggcccgccgc ctggactgcc cggcacacct
    20821 cacacacccc ttacgtggct ttgacaagcc cttgatgcgc gctcagccgg ccccggcatt
    20881 gccggacccc ggcagcgcat ccaccccggt caggcccgaa ccccggacca tgcgttagaa
    20941 aggcgtcaaa agacggaacg gatcgggggc gtacatggcg gagcgggacg tgccggagga
    21001 gtacctggag ggctatgcgc ggattctcgc cgacgcctcc gcgaccggcc gccggctgac
    21061 ccgggacgaa ctcgattccc gccgggccct aggcgagcag gccgcggagg ccggcttcgg
    21121 gctgcgtgcc ctggtcggag cgcacctcgc cgcgacccgg acgcactggc cggctcgcaa
    21181 gggcgcctgc gccgacacca tcatggccgc cgccgcgcag gccctcgacg cgttcgccga
    21241 ggggtacgag cgtgcccagc ggcatgccgt acgccaggag gaagccgccc gtcgtgagtt
    21301 catcgacgac ctgctgtacg gccgcagcga cctgggccga ctcgcccagc gcgcggaacg
    21361 ctacgggctg cggctgtcta ccgcgcacgc cgtcgccgtg gcacgcggcg aggcggctta
    21421 cgacgaggga gacgtcgttc cgcaggacgt ggagcgtgcg ctgatagccc ggttcggcga
    21481 ccgcagcatc ctgctgacca ccaaggacgg ccgcctggtg tgcatcgcac cgggcgacca
    21541 ggacgaggtc ctggcgttct tcgccaagca ggcgtacgcc gccacgaacg gcggccgggt
    21601 ggcgatcggc cggccccagc ccggcgcggc cggtgtcgtc cagtcgtacg aggaagccct
    21661 gaacaccctc gacctggccg accgcctcga actcgacgag cctgtgctgc gcgccgccga
    21721 cctcctcgtc taccccgttc tcgcccgcga ccggcaggcg atgaccgacc tggtggccag
    21781 cgtcctcggc cccctgcaac gggcccgcgg cggagccgag ccgctgctgg agacgctcac
    21841 cgcctacttc gacgccggct gtgtggccac ggtggcggcg cgccggctgt cgctgagcgt
    21901 gcgcgccttc acctaccgcc tggagcgcat ccacaagctc accggagccg atccgtccga
    21961 cccggtgcac cgttacaccc tgcagacagc ggtgatcggc gcccgtctgc tcggctggcc
    22021 gacctaggtt ctgcccagcc ggtctccggc gcgacggtga agggggtttt ggggggcgac
    22081 ggtccgtcct cgggtcacgt gcgggtggac ggtccgctgt cctcgttcgt cgtcttcgtc
    22141 tcggccttga ggatccgtgc cgacttgccc gccgaacggg ccagttccgg cagcttcttg
    22201 gcggccagga cggctatgac gacgatcagg atgatcgcga gttcgctcag tccgaacatg
    22261 gcagggccgc ccctcagacg ttgacgccga agtcggacgc gatgccggcg agcccggagg
    22321 cgtatccctg gccgacggcg cggaacttcc actccgcgcc gtgccggtac agctcgccga
    22381 agaccatggc ggtctcggtg gaggcgtcct cggaaaggtc gtaacgggcg atctcggcgc
    22441 cgccg
//
