LOCUS       NZ_CP077098            22113 bp    DNA     circular CON 03-MAR-2024
DEFINITION  Staphylococcus aureus strain RGB-095930 chromosome, complete genome.
ACCESSION   NZ_CP077098
VERSION     NZ_CP077098.1
KEYWORDS    RefSeq.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
            Staphylococcus.
REFERENCE   1  (bases 1 to 2904556)
  AUTHORS   Burgold-Voigt,S., Monecke,S., Simbeck,A., Holzmann,T., Kieninger,B.,
            Liebler-Tenorio,E.M., Braun,S.D., Collatz,M., Diezel,C., Muller,E.,
            Schneider-Brachert,W. and Ehricht,R.
  TITLE     Characterisation and Molecular Analysis of an Unusual Chimeric
            Methicillin Resistant Staphylococcus Aureus Strain and its
            Bacteriophages
  JOURNAL   Front Genet 12, 723958 (2021)
   PUBMED   34868203
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2904556)
  AUTHORS   Burgold-Voigt,S., Braun,S.D., Kieninger,B. and Monecke,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JUN-2021) Optisch-Molekulare Diagnostik und
            Systemtechnologien, Leibniz Institute of Photonic Technology (IPHT),
            Philosophenweg 7, Jena 07743, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 25-FEB-2021
            Assembly Method                   :: Flye v. 2.8-b1674
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 169.0x
            Sequencing Technology :: Oxford Nanopore MinION; Illumina MiniSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 03/03/2024 14:14:11
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,951
            CDSs (total)                      :: 2,873
            Genes (coding)                    :: 2,772
            CDSs (with protein)               :: 2,772
            Genes (RNA)                       :: 78
            rRNAs                             :: 7, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 43 of 101
            Pseudo Genes (incomplete)         :: 55 of 101
            Pseudo Genes (internal stop)      :: 22 of 101
            Pseudo Genes (multiple problems)  :: 17 of 101
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 14:14:16
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2630784
            Orig. end                         :: 2652897
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP077098.1.
            Bacteria and source DNA available from Prof. Wulf
            Schneider-Brachert, Department of Infection Prevention and
            Infectious Diseases, University Hospital Regensburg, Regensburg,
            Germany.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22113
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="opine-like-metallophore"
                     /region_number="8"
                     /rules="(CntL and CntM)"
                     /tool="antismash"
     cand_cluster    1..22113
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(CntL and CntM)"
                     /kind="single"
                     /product="opine-like-metallophore"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22113
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[10000:12113](-)"
                     /cutoff="5000"
                     /detection_rule="(CntL and CntM)"
                     /neighbourhood="10000"
                     /product="opine-like-metallophore"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12113)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="(CntL and CntM)"
                     /neighbourhood="10000"
                     /product="opine-like-metallophore"
                     /protocluster_number="1"
     misc_feature    complement(37..52)
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 23.64"
                     /tool="antismash"
     misc_feature    305..314
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 15.26"
                     /tool="antismash"
     gene            319..774
                     /locus_tag="KSF82_RS13395"
                     /old_locus_tag="KSF82_13385"
     CDS             319..774
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501218.1"
                     /locus_tag="KSF82_RS13395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KSF82_13385"
                     /product="YehR family lipoprotein"
                     /protein_id="WP_000732090.1"
                     /transl_table=11
                     /translation="MKKLCSLIVVALVCVIALSACGKEQTKTYEGDVSGKHVLTSITYK
                     DDKVLKQSTINTIKYDDLGMDKDEAKKLFAKSESIFKDLKGVKYKVDYKDKKAIEHLDI
                     DYTEVDMKKLNKRLGVSTKENKDISFEKLEKQLKHRGLKEKDKMDDK"
     misc_feature    complement(359..369)
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.94"
                     /tool="antismash"
     gene            complement(942..2519)
                     /locus_tag="KSF82_RS13400"
                     /old_locus_tag="KSF82_13390"
     CDS             complement(942..2519)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501219.1"
                     /locus_tag="KSF82_RS13400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KSF82_13390"
                     /product="FMN-binding glutamate synthase family protein"
                     /protein_id="WP_000143488.1"
                     /transl_table=11
                     /translation="MTFLTVMQFIVNIIIIGFLLTVMVIGLIWLIKDKRQSQHSVLRNY
                     PLLARIRYISEKMGPELRQYLFSGDNEGKPFSRNDYKNIVLAGKYNSRMTSFGTTKDYQ
                     DGFYIQNTMFPMQRNEISVDNTTLLSTFIYKIANERLFSREEYRVPTKIDPYYLSDDHA
                     IKLGEHLKHPFILKRIVGQSGMSYGALGKNAITALSKGLAKAGTWMNTGEGGLSEYHLK
                     GNGDIIFQIGPGLFGVRDKEGNFSEGLFKEVAQLSNVRAFELKLAQGAKTRGGHMEAEK
                     VNEEIAKIRNVEPYKTINSPNRYEFIHNAEDLIRFVDQLQQLGQKPVGFKIVVSKVSEI
                     ETLVRTMVELDKYPSFITIDGGEGGTGATFQELQDGVGLPLFTALPIVSGMLEKYGIRD
                     KVKLAASGKLVTPDKIAIALGLGADFVNIARGMMISVGCIMSQQCHMNTCPVGVATTDA
                     KKEKALIVGEKQYRVTNYVTSLHEGLFNIAAAVGVSSPTEITADHIVYRKVDGELQTIH
                     DYKLKLIS"
     gene            2714..3463
                     /gene="lnsB"
                     /locus_tag="KSF82_RS13405"
                     /old_locus_tag="KSF82_13395"
     CDS             2714..3463
                     /codon_start=1
                     /gene="lnsB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501220.1"
                     /locus_tag="KSF82_RS13405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KSF82_13395"
                     /product="CPBP family lipoprotein N-acylation protein LnsB"
                     /protein_id="WP_089535292.1"
                     /transl_table=11
                     /translation="MSNTNKHSIEEEYATEQSRFFKRDIGFIFLYIFLVNILPIIIVFL
                     TFGLVAVFTQQAPWGFSFPISMNISYLLAVIISLAIFRLMHEDAFIPMIRMQIVASAKY
                     KWHILISFTLSIVLFLLLNHFDIFALNVDSFTVFDIYPLIRDYGSISLIAIFSLTIILN
                     TLICQLIFRHILIQELSRLIPLKITIVLSVILETLYYYPYINTWWEFIPALILASSATY
                     LYLKSNRNFMVSYFYQLAVILVLHIFM"
     gene            complement(3687..4880)
                     /locus_tag="KSF82_RS13410"
                     /old_locus_tag="KSF82_13400"
     CDS             complement(3687..4880)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1202: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501221.1"
                     /locus_tag="KSF82_RS13410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KSF82_13400"
                     /product="MFS transporter"
                     /protein_id="WP_000675407.1"
                     /transl_table=11
                     /translation="MKGAMAWPFLRLYILTLMFFSANAILNVFIPLRGHDLGATNTVIG
                     IVMGAYMLTAMVFRPWAGQIIARVGPIKVLRIILIINAIALIIYGFTGLEGYFVARVMQ
                     GVCTAFFSMSLQLGIIDALPEEHRSEGVSLYSLFSTIPNLIGPLVAVGIWNANNISLFA
                     IVIIFIALTTTFFGYRVTFAEQEPDTSDKIEKMPFNAVTVFAQFFKNKELLNSGIIMIV
                     ASIVFGAVSTFVPLYTVSLGFANAGIFLTIQAIAVVVARFYLRKYIPSDGMWHPKYMVS
                     VLSLLVIASFVVAFGPQVGAIIFYGSAILIGMTQAMVYPTLTSYLSFVLPKVGRNMLLG
                     LFIACADLGISLGGALMGPISDLVGFKWMYLICGMLVIVIMIMSLLKKPTPRPANSL"
     gene            complement(4892..5641)
                     /locus_tag="KSF82_RS13415"
                     /old_locus_tag="KSF82_13405"
     CDS             complement(4892..5641)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501222.1"
                     /locus_tag="KSF82_RS13415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KSF82_13405"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_089535293.1"
                     /transl_table=11
                     /translation="MIKIKDVEKSYQSAHVFKRRRTPIVKGVSFECPIGATIAIIGESG
                     SGKSTLSRMILGIEKPDKGCVTLNDQPMHKKKVRRHQIGAVFQDYTSSLHPFQTVREIL
                     FEVMCQCDGQPKDVMEVQAITLLEEVGLSKAYMDKYPNMLSGGEAQRVAIARAICINPK
                     YILFDEAISSLDMSIQTQILDLLIHLRETRQLSYIFITHDIQAATYLCDQLIIFKNGKI
                     EEKIPTSTLHKSDNAYTRELIEKQLSF"
     gene            complement(5634..6449)
                     /locus_tag="KSF82_RS13420"
                     /old_locus_tag="KSF82_13410"
     CDS             complement(5634..6449)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501223.1"
                     /locus_tag="KSF82_RS13420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KSF82_13410"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_070974201.1"
                     /transl_table=11
                     /translation="MTLLTVKHLTITDTWTGQPLVSDVNFTLTKGETLGVIGESGSGKS
                     ITCKSIVGLNPERLRVTGDITFDGTSMLSLSESQLKKYRGKDIAMVMQQGSRAFDPSTT
                     VGKQMFETMKVHTSMSTQEIEKTLIEYMDYLSLKDPKRILKSYPYMLSGGMLQRLMIAL
                     ALALKPKLIIADEPTTALDTITQYDVLEAFIDIKKHFDCAMIFISHDLTVINKIADRVV
                     VMKNGQLIEHGTRESVLHHPEHVYTKYLLSTKKKINDHFKHVMRGDVCD"
     gene            complement(6446..7315)
                     /gene="opp1C"
                     /locus_tag="KSF82_RS13425"
                     /old_locus_tag="KSF82_13415"
     CDS             complement(6446..7315)
                     /GO_component="GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="opp1C"
                     /gene_functions="transport (smcogs) SMCOG1085:
                     binding-protein-dependent transport systems"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501224.1"
                     /locus_tag="KSF82_RS13425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KSF82_13415"
                     /product="nickel/cobalt ABC transporter permease"
                     /protein_id="WP_000584765.1"
                     /transl_table=11
                     /translation="MIILKRLLQDKGAVIALGIIVLYVFLGLAAPLVTFYDPNHIDTAN
                     KFAGMSFQHLLGTDHLGRDILTRLIYAIRPSLLYVFVALFVSVLIGSILGFLSGYFQGF
                     VDALIMRACDVMLAFPSYVVTLALIALFGMGAENIIMAFILTRWAWFCRVIRTSVMQYT
                     ASDHVRFAKTIGMNDMKIIHKHIMPLTLADIAIISSSSMCSMILQISGFSFLGLGVKAP
                     TAEWGMMLNEARKVMFTHPEMMFAPGIAIVIIVMAFNFLSDALQIAIDPRISSKDKLRS
                     VKKGVVQS"
     gene            complement(7312..8247)
                     /gene="opp1B"
                     /locus_tag="KSF82_RS13430"
                     /old_locus_tag="KSF82_13420"
     CDS             complement(7312..8247)
                     /GO_component="GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="opp1B"
                     /gene_functions="transport (smcogs) SMCOG1118:
                     binding-protein-dependent transport systems"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501225.1"
                     /locus_tag="KSF82_RS13430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KSF82_13420"
                     /product="nickel/cobalt ABC transporter permease"
                     /protein_id="WP_000472235.1"
                     /transl_table=11
                     /translation="MFKFILKRIALMFPLMIVVSFMTFLLTYITNENPAVTILHAQGTP
                     NVTPELIAETNEKYGFNDPLLIQYKNWLLEAMQFNFGTSYITGDPVAERIGPAFMNTLK
                     LTIISSVMVMITSIILGVVSALKRGKFTDRAIRSVAFFLTALPSYWIASILIIYVSVKL
                     NILPTSGLTGPESYILPVIVITIAYAGIYFRNVRRSMVEQLNEDYVLYLRASGVKSITL
                     MLHVLRNALQVAVSIFCMSIPMIMGGLVVIEYIFAWPGLGQLSLKAILEHDFPVIQAYV
                     LIVAVLFIVFNTLADIINALLNPRLREGAR"
     gene            complement(8260..9858)
                     /gene="cntA"
                     /locus_tag="KSF82_RS13435"
                     /old_locus_tag="KSF82_13425"
     CDS             complement(8260..9858)
                     /codon_start=1
                     /gene="cntA"
                     /gene_functions="transport (smcogs) SMCOG1068:
                     extracellular solute-binding protein family 5"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501226.1"
                     /locus_tag="KSF82_RS13435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KSF82_13425"
                     /product="staphylopine-dependent metal ABC transporter
                     substrate-binding protein CntA"
                     /protein_id="WP_001229077.1"
                     /transl_table=11
                     /translation="MRKLTKMSAMLLASGLILTGCGGNKGLEEKKENKQLTYTTVKDIG
                     DMNPHVYGGSMSAESMIYEPLVRNTKDGIKPLLAKKWDVSEDGKTYTFHLRDDVKFHDG
                     TPFDADAVKKNIDAVQENKKLHSWLKISTLIDNVKVKDKYTVELNLKEAYQPALAELAM
                     PRPYVFVSPKDFKNGTTKDGVKKFDGTGPFKLGEHKKDESADFNKNDQYWGEKSKLNKV
                     QAKVMPAGETAFLSMKKGETNFAFTDDRGTDSLDKDSLKQLKDTGDYQVKRSQPMNTKM
                     LVVNSGKKDNAVSDKTVRQAIGHMVNRDKIAKEILDGQEKPATQLFAKNVTDINFDMPT
                     RKYDLKKAESLLDEAGWKKGKDSDVRQKDGKNLEMAMYYDKGSSSQKEQAEYLQAEFKK
                     MGIKLNINGETSDKIAERRTSGDYDLMFNQTWGLLYDPQSTIAAFKAKNGYESATSGIE
                     NKDKIYNSIDDAFKIQNGKERSDAYKNILKQIDDEGIFIPISHGSMTVVAPKDLEKVSF
                     TQSQYELPFNEMQYK"
     misc_feature    complement(9825..9835)
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 19.14"
                     /tool="antismash"
     gene            complement(10001..11302)
                     /gene="cntM"
                     /locus_tag="KSF82_RS13440"
                     /old_locus_tag="KSF82_13430"
     CDS             complement(10001..11302)
                     /codon_start=1
                     /gene="cntM"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     opine-like-metallophore: CntM"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040598.1"
                     /locus_tag="KSF82_RS13440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KSF82_13430"
                     /product="staphylopine dehydrogenase CntM"
                     /protein_id="WP_072512057.1"
                     /sec_met_domain="CntM (E-value: 4.7e-213, bitscore: 705.0,
                     seeds: 4, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKLLMIGTGPVAIQLANICYLKSDYEIDMVGRASTSEKSKRLYQ
                     AYKKEKQFEVKIQNEAHQHLEGKFEINRLYKNVKNVKGEYETVVMACTADAYYDTLQQL
                     SLETLQSVKHVILISPTFGSQMIVEQFMSKFSQDIEVISFSTYLGDTRIVDKEAPNHVL
                     TTGVKKKLYMGSTYSNSTMCQRISVLAEQLKIQLEVVESPLHAETRNSSLYVHPPLFMN
                     DFSLKAIFEGTDVPVYVYKLFPEGPITMTLIREMRLMWKEMMAILQAFRVPSVNLLQFM
                     VKENYPVRPETLDEGDIEHFEILPDILQEYLLYVRYTAILIDPFSQPDENGHYFDFSAV
                     PFKQVYKNEQDVVQIPRMPSEDYYRTAMIQHIGKMLGIKTPMIDQFLTRYEASCQAYKD
                     MHQDQQLSSQFNTNLFEEDKALVTKFLEINRTLS"
     gene            complement(11295..12113)
                     /gene="cntL"
                     /locus_tag="KSF82_RS13445"
                     /old_locus_tag="KSF82_13435"
     CDS             complement(11295..12113)
                     /codon_start=1
                     /gene="cntL"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     opine-like-metallophore: CntL"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501228.1"
                     /locus_tag="KSF82_RS13445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KSF82_13435"
                     /product="D-histidine (S)-2-aminobutanoyltransferase CntL"
                     /protein_id="WP_001058850.1"
                     /sec_met_domain="CntL (E-value: 2.2e-129, bitscore: 428.0,
                     seeds: 4, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNNFNNEIKLILQQYLEKFEAHYERVLQDDQYIEALETLMDDYSE
                     FILNPIYEQQFNAWRDVEEKAQLINSLQYITAQCVKQVEVIRARRLLDGQASTTGYFDN
                     IEHCIDEEFGQCSIASNDKLLLVGSGAYPMTLIQVAKETGASVIGIDIDPQAVDLGRRI
                     VNVLAPNEDITITDQKVSELKDIKDVTHIIFSSTIPLKYSILEELYDLTNENVVVAMRF
                     GDGIKAIFNYPSQETAEDKWQCVNKHMRPQQIFDIALYKKAAIKVGITDV"
     gene            complement(12124..12945)
                     /gene="cntK"
                     /locus_tag="KSF82_RS13450"
                     /old_locus_tag="KSF82_13440"
     CDS             complement(12124..12945)
                     /codon_start=1
                     /gene="cntK"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501229.1"
                     /locus_tag="KSF82_RS13450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KSF82_13440"
                     /product="histidine racemase CntK"
                     /protein_id="WP_001081687.1"
                     /transl_table=11
                     /translation="MNRQVIEFSKYNPSGNMTILVHSKHDASEYASIANQLMAATHVCC
                     EQVGFIESTQNDDGNDFHLVMSGNEFCGNATMSYIHHLQESHLLKDQQFKVKVSGCSDL
                     VQCAIHDCQYYEVQMPQAHRVVPTTINMGNHSWKAIEIIYETYVHYVIPVKQVTTEIQH
                     LVETYVRKQQWNHKYKTVGMMLFDEQRQFLQPLIYIPEIQSLIWENSCGSGTASIGVFN
                     NYQRNDACKDFTVHQPGGSILVTSKRCHQLGYQTSIKGQVTTVATGKAYIE"
     misc_feature    13335..13348
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 17.65"
                     /tool="antismash"
     misc_feature    complement(13515..13533)
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: medium, score: 27.24"
                     /tool="antismash"
     misc_feature    complement(13518..13533)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 23.06"
                     /tool="antismash"
     misc_feature    13541..13552
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 19.59"
                     /tool="antismash"
     gene            complement(13887..14249)
                     /locus_tag="KSF82_RS13455"
                     /old_locus_tag="KSF82_13445"
     CDS             complement(13887..14249)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000910575.1"
                     /locus_tag="KSF82_RS13455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KSF82_13445"
                     /product="hypothetical protein"
                     /protein_id="WP_000910577.1"
                     /transl_table=11
                     /translation="MLKEKESFRLLYQAIREIADKIGDNQLETNSVSLLLLDFDFEHEV
                     FDELYLAILKYLNTVSIENISHSELLNLIENTIPEDREINTFVKNKIIIGFANNYFPEL
                     QVLANEIKSDMASSLK"
     gene            complement(14512..15330)
                     /locus_tag="KSF82_RS13460"
                     /old_locus_tag="KSF82_13450"
     CDS             complement(14512..15330)
                     /NRPS_PKS="Domain: PKS_KR (7-166). E-value: 1.1e-07. Score:
                     23.9. Matches aSDomain:
                     nrpspksdomains_KSF82_RS13460_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001620216.1"
                     /locus_tag="KSF82_RS13460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KSF82_13450"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_089535294.1"
                     /sec_met_domain="adh_short (E-value: 2.9e-30, bitscore:
                     103.0, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short_C2 (E-value: 8.3e-37, bitscore:
                     124.9, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKRLENKVAVVTGASTGIGQASAIALAQEGAYVLAVDIAEAVSET
                     VDKIKSNGDKAKAYIVDIASEQQIDNLASEIREQIGHVEVLFNNAGVDNAAGRIHEYPT
                     DVYDKIMNVDMRGTFLMTKMMLPLMMTKGGSIVNTSSFSGQAADLYRSGYNAAKGAVIN
                     FTKSIAIEYGRDGIRANAIAPGTIETPLVDKLTGTSEDKEGKTFRENQKWMTPLGRLGK
                     PEEVGKLVVFLASDESSFITGETIRIDGGVMAYTWPGEMLSDDSWKRTLE"
     aSDomain        complement(14833..15309)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_KSF82_RS13460_PKS_KR.1"
                     /evalue="1.10E-07"
                     /label="KSF82_RS13460_PKS_KR.1"
                     /locus_tag="KSF82_RS13460"
                     /protein_end="166"
                     /protein_start="7"
                     /score="23.9"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="VAVVTGASTGIGQASAIALAQEGAYVLAVDIAEAVSETVDKIKSN
                     GDKAKAYIVDIASEQQIDNLASEIREQIGHVEVLFNNAGVDNAAGRIHEYPTDVYDKIM
                     NVDMRGTFLMTKMMLPLMMTKGGSIVNTSSFSGQAADLYRSGYNAAKGAVINFTK"
     CDS_motif       complement(15238..15303)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_KSF82_RS13460_0001"
                     /evalue="1.80E-03"
                     /label="PKSI-KR_m1"
                     /locus_tag="KSF82_RS13460"
                     /protein_end="31"
                     /protein_start="9"
                     /score="11.0"
                     /tool="antismash"
                     /translation="VVTGASTGIGQASAIALAQEGA"
     misc_feature    complement(15490..15504)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     strong, score: 25.67"
                     /tool="antismash"
     gene            15565..17103
                     /locus_tag="KSF82_RS13465"
                     /old_locus_tag="KSF82_13455"
     CDS             15565..17103
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501232.1"
                     /locus_tag="KSF82_RS13465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KSF82_13455"
                     /product="AbgT family transporter"
                     /protein_id="WP_089535295.1"
                     /transl_table=11
                     /translation="MTSKHQQKGSIVNRFLNSVEKIGNKLPDPSVLFFLMCVGLAIMTW
                     VISLFNVSVKHPGTHQTIYIKNIISHDGFTMIMNDTIKNFSEFPALGLVLAVMIGIGVA
                     EKTGYFDKLMISVVNRAPRFLILPTIILIGILGSTAGDAATIILPPLAAMLFIKIGYHP
                     IAGLTMAYASAVGGFAANIVVGMQDALVYSFTEPATRIVSDSIKTNVAMNWYFIAASVI
                     VLLPTILLVTTKLIIPRLGQYDDRLMHDDHEETSSHITDKEAHALKWANISFIVTIILL
                     IITAIPEHSFLRNAKTGSLLDDAPLINGVGLIILVVFLVPGLVYGILSKEIKNTKDLGK
                     MFGDAVGTMGTFIVIVFFAAQLLAYLKWSNLGIIAAVKGAKLLEHQNGIVLILGIIVLS
                     AMVNMLIGSASAKWGILGPIFVPMLILIGFHPAFTQVIYRVGDSITNPITPMMPYLPLL
                     LTYAQKYDKRMKLGALLSSLMPYSIALSIVWTVFVIIWFLLGIPVGPGGPIFVK"
     gene            complement(17215..17637)
                     /locus_tag="KSF82_RS13470"
                     /old_locus_tag="KSF82_13460"
     CDS             complement(17215..17637)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501233.1"
                     /locus_tag="KSF82_RS13470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KSF82_13460"
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="WP_001146763.1"
                     /transl_table=11
                     /translation="MPYNYKKQNGELMSVMSQGEKFIHQSPVNDELSALIKLLISKING
                     CHYCVDIHKKELKELGVTQMKIDEVLSFRHLDLFTDQEKVTLEFAEMLNSIKDFKKFEI
                     IDRLKSFYDEEQIIDLVFVVNQINGWNRLNIISDRL"
     gene            complement(18090..18509)
                     /locus_tag="KSF82_RS13475"
                     /old_locus_tag="KSF82_13465"
                     /pseudo=""
     CDS             complement(18090..18509)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501235.1"
                     /locus_tag="KSF82_RS13475"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="KSF82_13465"
                     /product="DUF1433 domain-containing protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MSKKKILILTSIILIILISVADIYLKKKYDEK"
     misc_feature    complement(18532..18550)
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: medium, score: 24.99"
                     /tool="antismash"
     misc_feature    18536..18554
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 26.47"
                     /tool="antismash"
     gene            complement(18788..19174)
                     /locus_tag="KSF82_RS13480"
                     /old_locus_tag="KSF82_13470"
                     /pseudo=""
     CDS             complement(18788..19174)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001621930.1"
                     /locus_tag="KSF82_RS13480"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="KSF82_13470"
                     /product="DUF1433 domain-containing protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MLIILIIVVCVYLKIKIDEK"
     gene            19242..20450
                     /locus_tag="KSF82_RS13485"
                     /old_locus_tag="KSF82_13475"
     CDS             19242..20450
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001084931.1"
                     /locus_tag="KSF82_RS13485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KSF82_13475"
                     /product="hypothetical protein"
                     /protein_id="WP_089535296.1"
                     /transl_table=11
                     /translation="MNNLHDKDVTYRELAKEAYDIKESQDEIDIENADKTRTTFRVVGF
                     RQNKFNGLKMAGLSPMDDNDNVNTDELYMIYAGTDRNLLADNGADLGEDLKILGGKLGG
                     GLRTPPTEEERKVYGDLDTKLIGEGGYIPSDILENPMTQSKESYIFTGALINKQKPKYV
                     YSAAHSLGGGLAMLNGVMYNFDGVRTFSAPNTYDLLPDEVKANYQAEKYDGRFINYVHR
                     SDKIGQYDLFAERIGTQIYGKDVERHRFLDFLNPFFAHGMDTFEFKGDNVRIKMDTDEM
                     SKIASDLKASCEFVDDAIKSYQKYMDDTKAAAKRIERKYTEKIRTGNYKHIKPSDIEDY
                     MEELSVSGKYEFYNDTAFETVMSELNRIRKNVESFADKLKHAGEKMESRDKEIGELYKI
                     FER"
     gene            20456..20770
                     /locus_tag="KSF82_RS13490"
                     /old_locus_tag="KSF82_13480"
     CDS             20456..20770
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000505991.1"
                     /locus_tag="KSF82_RS13490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KSF82_13480"
                     /product="hypothetical protein"
                     /protein_id="WP_089535297.1"
                     /transl_table=11
                     /translation="MSFLDDLAESIEEQSDLSEFKQAMKNELQTKVEEAKTKIESIDED
                     IWDWQTTVNNKRDAIEEYCEGKTAEHAIERLMQDKQDIAGMRWTAEDAEKSCKVGSWFW
                     "
     gene            complement(20879..21301)
                     /locus_tag="KSF82_RS13495"
                     /old_locus_tag="KSF82_13485"
     CDS             complement(20879..21301)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501237.1"
                     /locus_tag="KSF82_RS13495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KSF82_13485"
                     /product="DUF1433 domain-containing protein"
                     /protein_id="WP_089535298.1"
                     /transl_table=11
                     /translation="MPKKTIFIIIGVILCISIVTGGIYLKMKHDEKEKQKEIYYKEQQE
                     RITLYLKHNTKEPNTIKTVHFTNLKTGPMGDAVIEGYINENKKDDFVAYGSPEHNYQFG
                     GSLIKSKKLSTLLKPGHQTKSPDEIKKELEDKKKDR"
     misc_feature    complement(21486..21503)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: strong, score: 21.55"
                     /tool="antismash"
     misc_feature    21729..21744
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 17.19"
                     /tool="antismash"
ORIGIN
        1 tgcttcttta acttgcattt cataaccagc aatgccgttt acatctgtta aatgtttaag
       61 taatttgact aactgattca tgttattcat cctcctgtat ttcaacttaa aactattgta
      121 tcactaactt tcagaaaaac gttccctacc gctttatctt tttcaggctt aataatttta
      181 aaaactttgt gagaaatccg cttcaaaaac ctcatattta caaaaaaatt atcaaaattt
      241 aaatttttga ataacatcat tttttagtaa atgttataat ttctttataa tacaaatatc
      301 gaaagaaggc gactgacttt gaaaaaatta tgttcattaa ttgtagtagc attagtttgt
      361 gtcattgcat tatcagcttg tggtaaagaa caaaccaaaa catatgaagg tgatgttagt
      421 ggtaaacatg tactaacttc tatcacatat aaagatgata aagttttaaa acagtctaca
      481 atcaacacaa ttaaatatga cgatctaggt atggataaag acgaagccaa aaagttattc
      541 gccaaatctg aaagtatttt caaagacctt aaaggcgtaa aatacaaagt agactataaa
      601 gataaaaaag caattgaaca cttagacata gattacacag aagttgacat gaaaaaatta
      661 aataaacgtc ttggtgtttc aactaaagaa aataaagata ttagttttga aaaacttgaa
      721 aagcaattaa agcacagagg cttaaaagaa aaagataaaa tggacgacaa atagtttata
      781 acataaaaat gccctcagat aagactaagg ttacaaacct taattcatat tctgagggct
      841 ttaatatttg aaattcttgt gtgaccagca tccactacta atataaaatt atttgcagta
      901 acgctaaaat ccgctgcttt cattttcccg aaataaataa gttaactaat gagttttaat
      961 ttataatcat gtatcgtttg caattcacca tcgacttttc gatatacaat atgatcagca
     1021 gtaatttctg taggactgga tacgccaaca gctgctgcaa tattgaataa gccttcatgc
     1081 aaacttgtta catagtttgt gacacgatat tgcttttctc caacaatcaa tgctttttct
     1141 tttttcgcat ctgtcgttgc aacacctaca ggacatgtat tcatatgaca ttgttgactc
     1201 ataatacaac cgacactaat catcatgcca cgtgcaatat taacaaaatc tgcacctaaa
     1261 cctagtgcaa tcgcaatttt atctggtgtc actaacttac cagatgctgc caatttcact
     1321 ttatctcgaa taccatattt ttctaacatg ccagacacaa taggtagagc tgtaaacagc
     1381 ggtaagccaa caccatcttg taattcttgg aatgttgcac cagtaccacc ttcaccacca
     1441 tcaatcgtaa taaagcttgg atacttatct agttccacca tcgtacgtac aagtgtttca
     1501 atttctgaaa ctttacttac tacaattttg aatcctactg gtttttgacc taattgctgc
     1561 aactgatcga cgaaacgaat caaatcttca gcattatgaa taaattcgta acggttaggt
     1621 gaattgattg ttttataagg ttcaacattt cggattttag caatttcttc gtttaccttt
     1681 tcagcttcca tatgaccacc acgagtctta gcaccttgtg ccaacttcag ttcaaatgca
     1741 cgtacgttag ataactgtgc gacctcttta aataaacctt cactaaaatt accttcctta
     1801 tcacgaacac caaataaacc gggaccaatt tggaaaatga tatccccatt accttttaaa
     1861 tgatattctg ataagccgcc ttcacctgta ttcatccaag tgcccgcttt agctagacct
     1921 ttagataaag ctgtaatggc attttttcct aaggctccat aactcatacc agattgtcct
     1981 acgatacgtt ttaaaataaa cggatgtttt aaatgttcac ctaattttat tgcatgatca
     2041 tcacttaagt aatacggatc aatctttgtc ggtacacgat attcttcacg actaaataaa
     2101 cgctcattcg cgattttata aatgaatgtt gataacaatg ttgtattatc tactgaaatc
     2161 tcattacgtt gcatcggaaa cattgtgttc tgtatgtaaa agccgtcttg ataatcttta
     2221 gtagtaccga agctggtcat acgagagtta tattttccag ccaaaacgat atttttataa
     2281 tcattacgtg aaaaaggttt cccttcatta tccccagaaa ataaatactg acgtaattcc
     2341 ggtcccattt tttctgaaat atatctaata cgtgctagta aaggataatt ccttaataca
     2401 ctatgttgtg attgtctttt atctttaatt aaccaaataa gcccgataac catgaccgta
     2461 agtaggaagc ctataatgat aatattaact ataaattgca tgactgtaag aaacgtcatt
     2521 acaatccctc ccccaaaaat ttcaattcac tatttatgat acaccttaca aaataaaaca
     2581 caatggaagc gcttcatttt ataaaacaat tttatgatat gtttttcatt ttaaatttta
     2641 atgtataaaa catacaatac aaagtaatat gtgctaaagt atctatataa tacaactatt
     2701 taagaggtat actatgtcaa atacaaataa acattccata gaagaagaat acgctaccga
     2761 acaatcgcgt tttttcaaac gtgatattgg atttattttc ctttatatat ttttggttaa
     2821 catcttgcca atcattatcg tctttttaac ttttgggtta gtagctgtat tcactcaaca
     2881 agccccatgg ggtttctctt ttcctatttc aatgaacatt agctatttac tcgcagttat
     2941 tatttcacta gctatttttc gtctgatgca tgaagatgcg tttattccaa tgatacgtat
     3001 gcaaatcgtt gccagtgcta aatataaatg gcatattctt atatcattta cattaagtat
     3061 cgtactcttt ttacttttaa atcatttcga tattttcgca ctaaatgtag attcctttac
     3121 tgtctttgac atttacccgc tcattagaga ctatggttcc atcagtttaa tagctatatt
     3181 ttcgttaacc attatattaa atactttgat ttgtcaactt attttccgtc atattttaat
     3241 tcaagaatta agcagattaa tacctttaaa gattacaata gtattatccg ttatccttga
     3301 aacactgtac tattatccat acattaatac atggtgggaa ttcattccag cattgatact
     3361 agctagtagt gcgacttact tatatttaaa atcaaaccgt aattttatgg tgagctattt
     3421 ctatcaatta gcagttatac tcgttttgca tattttcatg taaaattttt cagaatatta
     3481 tccattatcc atacacatca aaaagcacac ttaaaagtca gtatcacaac tcacttttaa
     3541 gcgtgcttta tttagatata ctatcgttct aaaaacgagc catatagaat gtttcatgtc
     3601 ctagcatgaa gcacatgaat cgccatgctc aatatacctt ttaaaattta aatattcatt
     3661 aacttaatat gctttaattc acttcattaa agactatttg ctgggcgtgg tgttggtttt
     3721 ttcaataaac tcataatcat tattacaatg actaacatac cacaaattag atacatccat
     3781 ttaaatccta ctaaatcgga aataggtccc atcaatgcgc cacctaacga tatacctaag
     3841 tctgcacagg caataaataa acctaacaac atattacgac ctacttttgg taagacgaaa
     3901 cttaagtatg atgttaatgt tgggtacacc attgcttgcg tcattcctat taatattgca
     3961 ctgccataga aaataattgc acctacttgc ggaccaaatg ccactacaaa tgacgcgatt
     4021 actaataatg atagtacaga taccatatat ttaggatgcc acataccatc tgacggaatg
     4081 tatttcctta agtaaaatct tgccacaaca actgcgatgg cctgtattgt caaaaagatt
     4141 cccgcattcg cgaatcctaa actcactgtg tataacggta caaatgtact aactgcacca
     4201 aatacaatcg atgcaacaat catgataata ccactgttca acaactcttt atttttgaaa
     4261 aattgcgcaa aaacagttac agcgttaaac ggcatttttt caatcttatc tgacgtatcg
     4321 ggttcctgtt cagcaaaggt cacgcgatag ccaaagaatg ttgttgttaa tgcgataaag
     4381 ataatgacaa ttgcaaatag tgaaatatta tttgcattcc aaatacctac ggcaactaat
     4441 ggtccgatta agtttggaat cgttgaaaat agcgagtaca atgatacacc ttcagaacga
     4501 tgttcctctg gtaatgcatc aataatacct agctgtaaag acatagaaaa gaatgccgta
     4561 cacacacctt gcataacacg tgctacgaaa taaccttcta atccagtaaa accataaata
     4621 attaaagcta tggcattgat aatcaaaata attcttaata ctttaatggg accgacacga
     4681 gcaataattt gtcctgccca tggtcgaaat accattgctg ttaacatgta tgcccccata
     4741 acgataccga taaccgtatt cgttgcgcct aaatcatgcc ctcgtaacgg tataaatacg
     4801 tttaagattg cattggcact aaagaacatc aatgttaata tatataatct caaaaagggc
     4861 caagccattg cacctttcat tatctcactc cttagaatga tagttgtttt tctattaatt
     4921 ctcttgtata agcattgtca cttttatgca atgtgcttgt tggaattttt tcttctattt
     4981 ttccgttttt aaaaataatt aattgatcac ataaatacgt ggcagcttga atatcatgtg
     5041 tgataaaaat ataactcaac tgacgcgttt cacgtaaatg aatcaataag tctaatattt
     5101 gtgtttgaat tgacatgtcg agtgaactaa tggcttcatc aaacaaaata tatttagggt
     5161 taatacatat tgcacgcgca atcgcaacac gctgcgcctc tccacctgat aacatattag
     5221 gatatttatc catgtatgcc ttagatagac cgacttcttc caacaatgta attgcttgga
     5281 cttccataac atctttaggt tgtccatcac attgacacat cacttcaaat aagatttctc
     5341 taacagtctg aaatggatgt aatgatgacg tataatcttg aaatacagca ccaatttgat
     5401 gacgtctcac tttcttctta tgcatcggtt gatcatttaa ggttacacaa cctttatccg
     5461 gtttctcaat acctaatatc atacgactca acgtcgattt accgctacca ctttctccga
     5521 taatcgcaat cgtcgcaccg attggacact caaatgacac acctttcacg ataggtgttc
     5581 gacgacgctt aaaaacatgt gcgctttgat atgacttttc aacatcttta attttaatca
     5641 catacatcac ccctcatcac atgtttaaaa tgatcattaa tcttcttctt agttgataat
     5701 aaatacttcg tataaacatg ttctggatga tgcaagactg attcacgcgt accatgctca
     5761 atcagttgac catttttcat cacaacaaca cggtctgcaa tcttgttaat aaccgttaaa
     5821 tcatgtgaaa tgaaaatcat cgcacagtca aagtgttttt ttatatctat aaatgcttcc
     5881 agtacatcat attgtgtaat tgtatctaaa gccgttgtcg gctcatcagc aatgattaac
     5941 tttggtttca aagctaacgc taaagcaatc atcaatcgct gtaacattcc tcctgataac
     6001 atgtaagggt atgattttaa tatacgttta ggatctttca aacttaaata atccatatat
     6061 tcaatcaatg tcttttcaat ttcttgtgta gacattgacg tatgtacttt catagtctca
     6121 aacatttgtt taccgacagt agttgatggg tcaaaggcac gactaccttg ttgcatgacc
     6181 atcgcaatat ctttaccacg gtactttttc agttgcgatt cggataatga caacattgat
     6241 gtaccatcaa aggttatatc acctgttacg cgtaatcgtt ctggatttaa acctacaatc
     6301 gatttgcatg taattgattt accgctacca ctttctccaa taacgcctaa agtttcaccc
     6361 ttagttaatg taaaattcac atcactcacg agtggttgac ctgtccaggt atctgtaatc
     6421 gtcaaatgct taactgttaa caatgtcatg attgcaccac tccttttttc acagaacgaa
     6481 gtttatcttt agaagagatg cggggatcaa tggcaatttg taaagcatcg gataagaagt
     6541 taaatgccat cactataatc acaatggcaa tacctggcgc aaacatcatt tcaggatgtg
     6601 taaacatcac ttttctagct tcgttaagca tcatacccca ctctgcagta ggcgctttga
     6661 cacctaatcc taaaaatgaa aagccagata tttgcaagat cattgaacac atcgagctac
     6721 tagagataat agcaatatct gctaatgtta acggcataat atgtttgtga atgattttca
     6781 tatcattcat accgattgtt ttagcaaatc ttacatggtc agaagcagtg tactgcataa
     6841 cacttgtacg tataacacga cagaaccatg cccaacgcgt caaaataaat gccatgataa
     6901 tattttcggc acccatacca aacaatgcaa ttaatgctaa cgttacaaca taacttggga
     6961 atgccaacat aacatcacac gcacgcatga ttaaggcgtc aacaaaccct tggaaatatc
     7021 ctgataagaa tcctaaaata gatccaataa gtacagaaac aaatagtgca acaaagacat
     7081 ataacaaact tggtctaatc gcataaatta acctagttaa aatatctcta cctaaatggt
     7141 cagtacctag tagatgttga aaactcatgc cagcaaattt gtttgctgta tcgatatggt
     7201 taggatcata aaatgtcaca agtggtgctg ctaatcctaa aaagacatat aatacaataa
     7261 tgcctaaagc aatcactgca cctttatctt gtaataatcg ttttaaaatt atcatcgtgc
     7321 gccctccctt aatcttggat ttaatagcgc attaatgata tctgctaatg tattaaatac
     7381 aataaataat accgctacaa ttaatacata tgcttgaatg actggaaaat catgttcaag
     7441 tattgctttt aaacttaatt gacctagtcc aggccatgca aagatatact cgataacaac
     7501 tagtcccccc attatcattg gtatagacat acaaaagatt gataccgcaa cttgtaaagc
     7561 attacgcaac acatgcaaca ttaatgtgat agatttcaca ccgcttgctc ttaaataaag
     7621 tacataatct tcatttaatt gttccaccat cgagcgtcta acatttctaa agtaaatacc
     7681 agcataggca atcgtaataa caatcactgg caatatgtaa ctttctggac ctgttaatcc
     7741 agaagtcggc aatatgttta acttcactga aacgtaaata ataagtattg aagctatcca
     7801 atatgatggt aatgcagtta gaaagaaagc cactgaacgt atcgcacgat cagtgaactt
     7861 tcctcttttt aatgcactaa ctacacctaa aataattgat gtaatcatca ccataacact
     7921 tgaaattatt gttaatttca atgtattcat aaatgctgga ccaatgcgtt cagcaacagg
     7981 atcacctgta atgtagcttg taccaaaatt aaattgcatc gcttcaagta accaattttt
     8041 atattgaatt aataatggat cattgaaacc gtacttctca ttcgtttctg caatcaactc
     8101 tggtgttaca tttggcgttc cttgtgcatg taaaattgtc acagctggat tttcatttgt
     8161 aatatacgtc aatagaaatg tcataaaact tactacaatc atcaatggaa acatgagcgc
     8221 aatacgtttt aagataaatt tgaacatcta aacgctcctt tatttatact gcatttcatt
     8281 gaatggtaat tcatactgtg attgtgtgaa tgatactttt tctaaatctt tcggcgcaac
     8341 aactgtcata ctaccgtgtg aaatagggat aaagatacct tcatcatcaa tttgtttcaa
     8401 aatgttttta taagcgtctg aacgctcttt accgttttgg attttaaatg cgtcatcaat
     8461 gctgttgtat attttatctt tgttctcaat gcctgatgtt gcactttcat aaccattttt
     8521 cgctttaaat gctgcaatag tactttgtgg atcgtacaat aatccccaag tttggttgaa
     8581 cattaagtca taatcaccag aagtacgacg ttcagcaatt ttatctgatg tttcgccatt
     8641 gatgtttaac ttaataccca ttttcttaaa ttctgcttgt aagtattctg cttgttcttt
     8701 ttgacttgaa gaacctttgt catagtacat tgccatttca aggtttttac catctttttg
     8761 acgaacatcg ctgtctttac ctttcttcca accagcttca tctaataatg attctgcttt
     8821 tttaaggtca tacttacgtg ttggcatatc gaaattaatg tctgttacat ttttcgcaaa
     8881 taattgagtt gctggttttt cttgaccatc taaaatttct ttggcaattt tatctctgtt
     8941 taccatatga ccaatcgctt gtctgactgt tttgtcactg acagcgttat cttttttacc
     9001 agaattgacc actaacattt tcgtattcat aggttgacta cgcttaactt gatagtcacc
     9061 tgtatctttc aattgtttta aagagtcttt gtctaagcta tctgtacctc tatcgtctgt
     9121 gaaggcaaag tttgtttcac cttttttcat tgataggaat gctgtttcac cagcaggcat
     9181 tacttttgct tgtactttgt taagtttaga cttttcgccc cagtattgat catttttatt
     9241 aaagtctgca gactcatctt ttttgtgttc acctaattta aatggaccag taccatcgaa
     9301 ctttttaacg ccatcttttg ttgtgccgtt tttaaagtct tttggagaca caaatacata
     9361 tggacgaggc atcgctaatt cagccaatgc aggttgatat gcttctttca aattcaattc
     9421 aaccgtgtac ttatctttaa ctttaacatt gtcaattaat gttgaaatct ttaaccaaga
     9481 atgcaatttt ttgttttctt gaactgcgtc aatatttttc ttaactgcgt cagcatcaaa
     9541 tggcgtacca tcatggaatt taacgtcatc tctcaaatgg aacgtgtatg tcttcccatc
     9601 ttcagacaca tcccattttt tagctagtaa aggcttaatc ccatctttcg tgttacgtac
     9661 aagcggctcg tatatcatac tttcagcaga catcgatcca ccgtaaacat gcgggttcat
     9721 atccccgata tctttaaccg tcgtatacgt taattgcttg ttttcttttt tctcctctaa
     9781 acctttatta ccgccacaac cagttaaaat tagccctgat gcaagtaaca ttgcactcat
     9841 tttagttagt tttctcattt gcttttcctc tttctaaatt gataagttgc attacttaat
     9901 caaatcgtaa tgattatttt tctcaattat ttgcttattt ttatgtaaat gtcaaacata
     9961 attcaataat ttttttctat tataaaactt caaaccctta ttatgaaagc gttctattga
    10021 tttccaaaaa ttttgtgacg agtgccttat cttcttcaaa taaatttgta ttaaattgag
    10081 aagatagttg ttgatcttga tgcatatcct tgtacgcttg acaacttgct tcatagcgag
    10141 ttaggaactg atcaatcatt ggcgttttga tacctagcat tttcccaata tgctgaatca
    10201 tcgctgttct gtaataatcc tcacttggca ttcttggaat ttgaacaaca tcctgttcat
    10261 ttttatagac ttgcttaaat ggtacagctg aaaaatcaaa gtaatgtccg ttttcgtctg
    10321 gctgtgaaaa tggatcaatg aggattgcgg tatatcttac ataaagtaga tattcttgta
    10381 agatatctgg caagatttcg aaatgctcaa tatcaccttc atccaaagtt tcaggacgta
    10441 ctggataatt ttccttcacc ataaattgaa gcaggttgac tgacggcact ctaaatgctt
    10501 gtaaaatagc catcatttcc ttccacatta aacgcatttc acggattagt gtcatcgtta
    10561 tcggtccttc aggaaataac ttatacacat aaaccggtac atccgttcct tcgaaaatgg
    10621 ctttcaatga aaagtcattc ataaatagtg gtgggtgcac ataaagcgaa ctgttacgtg
    10681 tttcagcatg cagtggcgat tcaacgactt ctaattgaat cttcaattgc tcagctaaaa
    10741 cagagattcg ttgacacatt gttgagtttg aatatgtcga acccatgtac aatttctttt
    10801 ttacacctgt tgtcaacaca tgattaggtg cttctttatc aacaatacgt gtatcgccaa
    10861 gataagttga aaatgaaatc acttcgatat cctgactgaa cttagacata aattgttcca
    10921 caatcatttg cgatccaaat gtcggtgaaa ttaaaatgac atgtttgaca ctttgcaaag
    10981 tttctaacga caattgctgt agtgtgtcat aataagcatc tgctgtacat gccatgacaa
    11041 ccgtttcgta ttcaccctta acgtttttaa cgtttttata caaacgatta atttcaaact
    11101 taccttccag atgttgatgc gcctcgtttt gtattttgac ttcaaattgt ttctcttttt
    11161 tatacgcttg atataagcgt tttgattttt ctgatgttga ggcacgtcca accatatcaa
    11221 tctcataatc tgattttaaa tagcaaatat tcgctaattg gattgcgacc ggaccagtgc
    11281 ctatcattaa taatttagac atccgtaata cctaccttta tagctgcttt tttataaagt
    11341 gctatatcaa aaatttgctg tggtctcata tgtttattca cacattgcca cttatcttcc
    11401 gctgtttctt gtgacggata attaaatatt gctttgatgc catcaccaaa gcgcattgca
    11461 actacgacat tttcatttgt taaatcatat aattcttcta aaatgctgta ctttaaagga
    11521 attgtcgagc tgaatatgat atgcgtcaca tctttgatat ctttaagttc agataccttt
    11581 tgatccgtaa ttgttatatc ttcatttggt gctaagacgt taacgattct gcgtcctagg
    11641 tcaacggctt gtggatcaat atcaataccg ataactgaag cacctgtttc ttttgctact
    11701 tgaattaacg tcattggata tgcacctgaa ccaactagca ataatttgtc attgctagct
    11761 atactacatt gtccaaactc ttcatcaata caatgttcta tattgtcaaa gtaacctgtg
    11821 gtagacgcct gtccgtctaa tagacgtcta gctctaatga cttccacttg tttaacacac
    11881 tgcgctgtaa tatattgcag tgaatttatt aattgtgctt tttcttcaac gtcacgccaa
    11941 gcattaaatt gttgttcata aataggattt aaaataaatt cactatagtc atccatcaat
    12001 gtttctaatg cttcgatata ttgatcgtct tgtaatacac gctcgtaatg cgcttcaaac
    12061 ttttctaaat attgttgtaa tatcaatttg atttcattat taaagttatt cattgtaggc
    12121 tccttattct atatatgctt ttcctgtagc tacagttgta acctgtcctt taattgaagt
    12181 ttgatatccc aattggtgac atcgctttga tgtcactaaa atactgcccc ctggctgatg
    12241 tactgtaaaa tctttgcatg cgtcattacg ttgataatta ttaaaaaccc caattgatgc
    12301 tgtaccagaa ccacagctat tttcccaaat taaactttgg atttctggta tatagattaa
    12361 tggctgtaaa aattgacgtt gttcatcaaa aagcatcata cctactgttt tatatttgtg
    12421 attccattgt tgcttacgca catacgtttc aaccaaatgt tgaatttctg ttgttacttg
    12481 tttaactgga atcacataat gtacatatgt ttcataaata atttctattg ctttccatga
    12541 atgattaccc atattaattg ttgttggcac aacacgatgg gcttgtggca tttgaacttc
    12601 atagtattgg caatcatgaa ttgcgcattg cactaaatcc gaacagccag acaccttcac
    12661 cttaaactgt tggtctttaa gcaaatgact ttcttgcaaa tgatgtatat atgacatcgt
    12721 cgcattaccg caaaattcat taccgctcat aactagatgg aaatcattgc catcatcatt
    12781 ttgtgttgat tctataaagc ctacctgttc acaacataca tgtgttgcgg ccatcaactg
    12841 attggcgata gatgcatatt cactagcatc atgttttgaa tgaacaagta tcgtcatatt
    12901 ccccgaagga ttatacttag aaaattctat aacctgccga ttcatacgac actcctttag
    12961 atgtattttt tagagcctct tttaccataa gtaattagag gctcttatgc agttggtgcg
    13021 aagcaagcaa ctgtattcct ctaaaactgt aattttaatt actagaggct cttatgcagt
    13081 tgttgcgaag caaacaactg tattcctcta tacctgtaat tttttagaag ttgaacctaa
    13141 tagctctatc tattaggtaa gtcatgctaa ttcccaaaag cgaaaagcat ggctttatat
    13201 gcagttgttg cgaagcaagc aactgtattc ctctatacct gtaatttttt agaagttgaa
    13261 cctaatagtt tcccatctat taggtaagtc atgctaaccc gcaaagtgga aagcatgact
    13321 tagtaatcgg ttgttgcatc aacatgcaac cgtaaacctt atttaaagtt gcttcttgtg
    13381 gctctacaag cgaatgcagt tgtccgttaa ctacattcac ttagatgctt ttactgtttt
    13441 cacctcaact aaaacttcaa aaaagttgca gaaaacaaat cgtaactatt acgatttgat
    13501 tatatactat attagttgag aatcattgtc aataaaggtt gtaaatgaaa gcacatttat
    13561 attttgataa tccttccata aacttcgtat tctcagcaca ttcaagtctt tttgaaaatt
    13621 tttatcaata attgagtaga agttccgttc tcgtcagttc aaaattttac gtaagttgtc
    13681 tctgcgtatt ggtttagtga gaataaccca cactagtgga aacgtccttt tgttaatcta
    13741 caatggacat ccttgtcttt cgctaacatt tcctattacc aatcctgtaa cggattttca
    13801 tcgtcaagtt gttctccatg caatgcgcac caaaaaagct tcgtacaatt tcgtacaaag
    13861 ctttaaaaat tcaaataaaa acatcattat tttaatgaac tagccatatc agattttatt
    13921 tcgtttgcta atacttgtaa ttcagggaaa taattattag caaagccaat tattatttta
    13981 ttttttacaa acgtgttaat ctctcgatct tctggaatcg tattttctat taaattcaaa
    14041 agctcactat gacttatgtt ctctatactt actgtattta aatattttaa aatcgcaaga
    14101 tacaattcat caaatacttc atgttcaaaa tcaaagtcca ataataataa actaacggaa
    14161 ttagtttcta actgattatc tccaatttta tctgcaatct ctcttatagc ttgatatagc
    14221 aatctaaaac tttctttttc ttttaacata aaattctcct taatttatta gaatagacaa
    14281 aatacagctt attttaaaga tactccaaaa gtttgaactc gagattctga taaattagat
    14341 gcacgaccta caatacgtta aaacaagctt taagcaatac acttcaaatg aacaatatgt
    14401 gattttcaaa gattaattaa tctccgattt aaatgtctgt cattgcgaca atatgcatac
    14461 attgcctact tcatgccaaa ttattttcca ctggatatcg attttaaata attattccaa
    14521 tgtccgcttc cacgaatcat cactcaacat ctcgccaggc catgtgtaag ccataacacc
    14581 accgtcaatg cgaattgttt caccagtaat aaatgaactc tcatcagatg ctaaaaagac
    14641 aacgagcttg cctacttctt ctggtttacc taaacgtccc agcggtgtca tccatttctg
    14701 attttctctg aatgttttgc cttccttatc ttcgctagta cctgtcagtt tatctactaa
    14761 cggggtttca atcgtacctg gtgcaatcgc attagctcga atgccatctc taccatattc
    14821 gattgcaatg gatttcgtaa aattaatcac tgcccctttc gcagcattat atcctgagcg
    14881 atacaaatct gctgcctgtc ctgaaaatga agatgtgtta acaatagaac cacctttagt
    14941 catcattaaa ggtaacatca ttttcgtcat caaaaatgtt ccacgcatat ctacattcat
    15001 aatcttgtca tatacatctg ttggatactc atgaattcta ccagcagcat tgtcaacgcc
    15061 tgcattatta aacaacactt caacatgccc aatctgttct ctaatttctg atgctaaatt
    15121 gtcaatttgt tgttcgcttg caatatccac aatataagcc tttgctttgt caccattact
    15181 tttaatttta tcgacagtct ccgataccgc ttcagctatg tctaccgcca atacatacgc
    15241 accttcttga gctaaagcga ttgcagaagc ttgtccgata cctgtacttg ctcctgttac
    15301 gactgcaact ttattttcca aacgtttcat tcagtcactc ctatacaaca tatcttaaac
    15361 ttacagtcct tattttccac tgttcaatgc tacataaacc taatagataa gtctccaggc
    15421 agtcttagct actctctgct atacaatttc tattgaataa ctcaaaatat ttaacaatat
    15481 tagtcttttc attttctgaa aattgttact tttgagagta ttttttggta cactttaaat
    15541 atttaacaaa gggaggaatc attgatgaca tcaaaacatc aacaaaaggg gtctatcgtc
    15601 aatcgtttct tgaatagtgt tgaaaaaatt ggaaataaat tgccagatcc tagcgtctta
    15661 ttctttttaa tgtgtgtggg cttagccatt atgacgtggg ttatctcatt atttaatgta
    15721 tctgttaagc atccaggtac gcatcaaacc atttatatta aaaatataat tagccatgat
    15781 ggatttacga tgataatgaa tgatacgatt aaaaatttct cagagttccc agcattaggc
    15841 ttagtactag cagtgatgat tggtattggt gttgcagaga aaacaggata cttcgacaag
    15901 ttaatgattt ctgttgtgaa tcgcgcacca cgtttcttaa ttttaccgac tattatatta
    15961 attggtattt taggtagtac agccggcgat gctgctacaa ttatcttgcc gccactcgca
    16021 gcgatgcttt ttattaaaat tggctatcac cctatcgctg gactaacgat ggcatatgct
    16081 tccgctgtag gtggctttgc cgcaaatata gtagttggta tgcaagatgc tttggtctat
    16141 tcatttacag aaccagcaac acgtatcgtt tcagattcta ttaaaacaaa cgttgctatg
    16201 aactggtact ttatcgcagc gagtgtcatt gtattacttc ctacgatatt gctagttaca
    16261 actaaactga ttattcctag gttaggtcaa tatgatgatc gtttaatgca tgatgatcat
    16321 gaagaaacgt cttcacatat tactgacaaa gaagcacatg ctttaaaatg ggcaaatatc
    16381 agtttcatag tcacaattat tttattaatt attacagcca ttcctgaaca tagcttttta
    16441 agaaatgcta aaacaggcag cttactagac gatgcgccat taattaacgg tgtcggatta
    16501 attattcttg tcgtattttt agtacctgga ttagtttatg ggattttaag caaagaaatt
    16561 aaaaatacaa aagacttagg taaaatgttc ggcgatgctg taggaacaat gggaacattt
    16621 atcgttattg tgttttttgc agcacagcta cttgcgtatt taaagtggag taatttagga
    16681 attatcgctg ctgttaaagg tgccaaatta ttagaacatc aaaacggtat tgtattgata
    16741 ctaggtatta ttgtactgag tgcaatggtc aacatgttaa tcggaagcgc atcggctaaa
    16801 tggggtattt taggaccgat attcgtacca atgttaatcc ttatcggctt tcatcccgca
    16861 ttcacacaag tcatttaccg tgtaggcgat tcaattacca atccaattac accgatgatg
    16921 ccgtacttac ctttattatt aacttatgca caaaaatacg ataaacgcat gaaactcgga
    16981 gccttacttt ctagtttaat gccgtattca atcgcgctaa gtattgtgtg gacagtattt
    17041 gtcatcattt ggttcctatt aggtatccct gtgggaccag gtggaccgat attcgttaaa
    17101 tagcagtatt caaagggata aattaaaatg ccactataca agattcgacc tgtatagtgg
    17161 catgatttgt tatgatatag cgttcgagat gaaactctgc atttatatga acaattatag
    17221 tctatcacta ataatattta atctgttcca accgttaatt tggtttacaa caaagacaag
    17281 atcaataatt tgttcttcat cataaaatga ttttagccgg tcaataattt caaacttctt
    17341 aaagtctttg attgaattta acatttctgc aaattcaagc gtcacttttt cttgatcagt
    17401 aaataaatct aaatgtctaa aactcaagac ttcatcaatt ttcatttgtg ttacacccaa
    17461 ttcctttaat tcttttttat ggatatcaac acaataatga caaccgttaa tttttgaaat
    17521 taataactta atcaatgcac taagttcatc attaacgggt gattgatgaa taaacttttc
    17581 accttggctc attacagaca ttaactctcc attttgtttc ttgtaattat acggcatttg
    17641 caatctctcc tttacattgt ttaataccaa tccagtgata ctacacttcg aacaatattg
    17701 gatagaattt gaaattctgt ataacatctt gtcaacctat gttttagtta aaacatttag
    17761 cgcttatatt taaaaaatgt ataaaatatg aaaacagatt gaaagaatat tataccttgc
    17821 tctacccttt tttataataa atcacacaca tttgagaaaa tttgataatg tcaataaatc
    17881 acgtcatcga cattgttatt cggtatataa tgtttttata atggccaaac tagtatttca
    17941 tttacattaa tagggttcac ttgtgttaat gtactgtaaa aaaattgggg aagtattggt
    18001 gatgatgaag tgattgatat taattgcgaa acaccttcga tagcaatgac atagattatt
    18061 ggaagattaa atcaaaaata aagaagaccc tagtggcctt cttttttgtc taattcttct
    18121 ttgatttcgt caggtgattt taattgattt gctggtttta gtaattcact taatttttca
    18181 ctttctatca tatctccacc aaattgataa tgatgttctg gagacccata tgcaacaaaa
    18241 tcagcttttt tgttttcatt gatgtaacct tcaattacgg catcgcccat gggtcctctt
    18301 tttaaacttg tgaaatgcac agatttaatc gtgttaggtt ctttagtatt atgcttgaga
    18361 tagagtgtaa tacgcgcttg ttgttcttta taataaattg atttttgctt ttatttttcg
    18421 tcatatttct tttttaaata gatatctgca acactaatta atatgattaa tataatacta
    18481 gttaatatta aaattttctt tttcgacata tatcaccagc tcctaaaccg tggtggaatt
    18541 ttatacagtt tacatgttta tgatactaca aaacacactc ttacaaagaa aaactataat
    18601 tttaatctag gtcaaggaaa agcagccaaa agtgttgata taaagttcat ctaaaatcaa
    18661 cgaaatattg tggatataaa gtggttaaca gataaataca gtggaatgtt gtactaaaaa
    18721 ttcaagtttt tatttttttg tgtaagtgtg attagcttga aagcaaaatt aaaacgaccg
    18781 catagtttta gtggtcgttc tttttagaat ctagttcttt ttttatatca tcaggcgttt
    18841 tggtttgatg tgctggtttt aataatgtgc ttaaattttt tcttttgatt aaacttccac
    18901 caaattgata atgatgttct ggagacccat atgcaacaaa atcatcttct ttattttcat
    18961 tgatgtaacc tttaattacg gcatcgccca taggttctct ttttaagttt gtgaaatgta
    19021 caggtttgat cgtgttcggt tctttagtgt tatgcttgag atagaatgtg atacgctcct
    19081 gttattcttt gtagtaaatt gctttttgtt tttatttttc atcaatttta atttttaaat
    19141 agacacacac aacaataatt aatataatca acataatact aataaatatt attttttaaa
    19201 ttttagttat aaacaaataa ctcctaaaat gaggtgacat tttgaataat ttacatgata
    19261 aagacgttac atatcgcgaa ctcgcaaaag aagcgtatga tattaaagaa agtcaagatg
    19321 aaatagatat cgaaaatgcc gataaaacta gaactacttt tagagtagta ggatttcgac
    19381 aaaataagtt taatggttta aagatggcag ggctatcacc tatggatgac aatgataatg
    19441 taaatacaga tgagttgtat atgatatatg cgggtacaga tcgtaatctt ttggctgata
    19501 atggggctga ccttggagaa gatttaaaaa ttttaggtgg aaaattggga ggaggattaa
    19561 gaacaccacc tactgaggaa gagcgtaaag tttatggtga tttggataca aagctaattg
    19621 gtgaaggagg ttacatacca tcagatatat tagaaaatcc tatgactcaa agtaaagagt
    19681 catatatttt tacaggtgcg ttaattaata aacaaaagcc aaaatatgta tatagtgctg
    19741 cacatagttt gggtggtggt ttagcaatgt tgaatggcgt gatgtataac tttgatggtg
    19801 tgcgaacttt ttcagcacca aatacatatg atttgttacc agacgaagtt aaagcgaatt
    19861 atcaggctga aaagtatgat ggtaggttta taaattacgt tcatcggtca gataaaattg
    19921 gtcagtacga tttatttgca gagcgtattg gtacacaaat atatggcaaa gatgtagaac
    19981 gtcatcgttt tttagacttt ctaaatccat ttttcgctca tggtatggat acatttgaat
    20041 ttaaaggtga taatgttcgt atcaaaatgg atacagatga aatgtcaaaa atagcaagtg
    20101 atttgaaagc atcgtgtgaa tttgtagatg atgctattaa atcttatcaa aagtatatgg
    20161 atgataccaa agcagctgcg aaacgaattg aaagaaaata tacagaaaaa ataagaacag
    20221 gtaattataa gcatataaaa ccatcagata tagaggatta catggaagaa ttatctgtat
    20281 cggggaaata tgaattttat aatgataccg catttgaaac agttatgagt gaattaaatc
    20341 gaattcgaaa gaatgttgaa tcttttgcgg acaaattaaa acatgcaggc gagaagatgg
    20401 aatcacgtga taaagaaata ggtgaattat ataaaatatt tgagaggtaa tgtatatgag
    20461 ttttttagat gatcttgcgg aaagcataga agagcaaagt gatttatctg aatttaaaca
    20521 agctatgaaa aatgagttac aaactaaagt ggaagaagct aaaacaaaaa ttgaatctat
    20581 tgatgaagat atttgggatt ggcaaacgac agtaaataat aagagagatg ctatcgaaga
    20641 atattgtgaa ggtaaaacgg ctgagcatgc aattgaaaga ctaatgcaag ataagcaaga
    20701 tatcgcaggt atgcgatgga cagcagaaga tgcagagaaa agctgtaaag tgggtagttg
    20761 gttttggtaa tataaaagaa aataaaatac gttaagaatt aaaattcagc tttactgtca
    20821 tttttgattg caatattata atattgcaat caaagataaa aagaaagacc gcgtgaaatt
    20881 agcggtcttt ctttttatct tctaattctt ttttgatttc atcaggtgat tttgtttgat
    20941 gtcctggttt taataatgtg ctcaattttt tacttttgat taaacttcca ccaaattgat
    21001 aattatgttc aggggatcca tatgcaacaa aatcatcttt tttattttca ttgatgtaac
    21061 cttcaattac ggcatcaccc ataggccctg tttttaaatt agtgaaatgt acagttttga
    21121 tggtattggg ttctttagta ttatgcttta gataaagcgt aatgcgctcc tgctgttctt
    21181 tgtagtaaat ttctttttgt ttttcttttt cgtcatgttt catttttaaa tagatacctc
    21241 cagtaactat agaaatacat aaaataacac cgataattat aaaaatagtt tttttgggca
    21301 ttaaaccagc tcctaatttt aagtgaaaga taaaaatttt atacttctgt ggttatgaat
    21361 gttatagatt aaagattata ggactaaact aatcttctcc agtaacctaa ctattatcat
    21421 tccctataat tgagcattaa attaaaaaga cgattaccaa atactctctt acaattaaat
    21481 atagtttaac accttgctaa caaaaataaa attaaactta ttttccaata ttaaaaattt
    21541 taaatacatg tgcatagcta acctatttaa aatatcttaa ttatataatt gttaaataaa
    21601 agaacacact aattctattg attaaaagta tctatatatc atttcaatcg cataataatt
    21661 tatatttata gctattacat taaatgccta tctcccacac ctcaaacacc tttttataca
    21721 ggacgcactg taatttcatt cacgttaacg tgctttggtt gtgttaatgc atataatact
    21781 gcttctgcaa tatcttgtgg ttcaagtttt ttacggtctg ttggattgta tgcggcagtt
    21841 attgctgtat ctaccattcc tggagaaatg cttgttactt taacacctgt ctttgccaac
    21901 tctttttcta atccttgagt aatagtgtga actgctgctt tcgtcgcact ataaatcgta
    21961 ctgcttttcg ttacttcaaa gccagaaata gatgcaatgt taataagatg gccacttgat
    22021 tgttctaaca tagttggtaa tgcagcctgt gccgtgtata aagtgccttt gatattcaca
    22081 tcaatcatac tatcccactc atctacttga taa
//
