LOCUS       NZ_CP080647            20339 bp    DNA     linear   CON 08-NOV-2024
DEFINITION  Streptomyces akebiae strain MG28 chromosome, complete genome.
ACCESSION   NZ_CP080647
VERSION     NZ_CP080647.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces akebiae
  ORGANISM  Streptomyces akebiae
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Kitasatosporales; Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 10257202)
  AUTHORS   Ping,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2021) College of Life and Environment Science,
            Hunan University of Arts and Science, No. 3150 Dongting Avenue,
            Changde, Hunan 415000, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. v. 3
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 120.0x
            Sequencing Technology             :: Oxford Nanopore PromethION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_019599145.1-RS_2024_11_06
            Annotation Date                   :: 11/06/2024 09:26:18
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 9,127
            CDSs (total)                      :: 9,036
            Genes (coding)                    :: 8,727
            CDSs (with protein)               :: 8,727
            Genes (RNA)                       :: 91
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 309
            CDSs (without protein)            :: 309
            Pseudo Genes (ambiguous residues) :: 0 of 309
            Pseudo Genes (frameshifted)       :: 142 of 309
            Pseudo Genes (incomplete)         :: 231 of 309
            Pseudo Genes (internal stop)      :: 20 of 309
            Pseudo Genes (multiple problems)  :: 77 of 309
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 03:57:32
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 9995500
            Orig. end                         :: 10015839
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP080647.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Mo Ping.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..20339
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="34"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..20339
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20339
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:10339](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..10339)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    complement(357..371)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.0"
                     /tool="antismash"
     misc_feature    complement(897..910)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 19.0"
                     /tool="antismash"
     gene            complement(1782..2870)
                     /locus_tag="K1J60_RS43325"
                     /old_locus_tag="K1J60_43325"
     CDS             complement(1782..2870)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1165: carboxylate-amine ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005474195.1"
                     /locus_tag="K1J60_RS43325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K1J60_43325"
                     /product="glutamate--cysteine ligase"
                     /protein_id="WP_220651013.1"
                     /transl_table=11
                     /translation="MRTVGVEEELLLVDPQTGEPQARAAAVLARAALEGTDQDVFEKEL
                     HDEQVEFATHPQSSMTDLGAEIVRCRKDAARHAEGLGSAVVALATSPLPVSPTITMNSR
                     YRWMAREFGLHTQVQLVCGCHVHVSVESDDEGVAVLDRMRPWLSVLTALSANSPFWQGY
                     DSRYASYRSQVWDMWPMAGPTDVFGSAERYHQCVTDLIATGVVRDQGMVYFDARLSQRY
                     PTVEIRVADVCLHPDTAVLVAALARGLVETAAREWRAGVEPLGHSAGLLRLATWRAARS
                     GMSENLLDPVTMRPRPALDVIRSLLHHVEGALVDHGDADLARDAVAALTGRGNGARVQR
                     EVMARTGSLREVVAACVRHTQA"
     gene            3052..3285
                     /locus_tag="K1J60_RS43330"
                     /old_locus_tag="K1J60_43330"
     CDS             3052..3285
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020138240.1"
                     /locus_tag="K1J60_RS43330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K1J60_43330"
                     /product="hypothetical protein"
                     /protein_id="WP_220651014.1"
                     /transl_table=11
                     /translation="MNSTTETGHVTGTADKDYNLIRYVEACLDNALRLESYIQDAEREK
                     DTEVVELFRKAQADSRKGADLGKELLRRRPSG"
     gene            3594..5021
                     /gene="rox"
                     /locus_tag="K1J60_RS43335"
                     /old_locus_tag="K1J60_43335"
     CDS             3594..5021
                     /GO_function="GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /gene="rox"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1050: monooxygenase FAD-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014669272.1"
                     /locus_tag="K1J60_RS43335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K1J60_43335"
                     /product="rifampin monooxygenase"
                     /protein_id="WP_220651015.1"
                     /transl_table=11
                     /translation="MIDVIVVGGGPTGLMLASELRLAGVGTVVLERLTEPTGESRGQGL
                     HARSVEVMDQRGLLDRFLAVSEKFRVGGLFGGIMKPWPESLDTAHAYGVATPQPVTERI
                     LQERALELGTDIRRGSELVGLDQDEDGVTARLADGTRLRARHLVGCDGGRSVVRKLLGV
                     GFPGEPATVETLLGDMGATEDPATIAAVVEEVRRTQLRFGLAPLGDGNYRVLVPAEGVS
                     EDRTTQPTLDEFKQRLRAFAGTDFGVHSPRWLSRFGDATRQAERYRVGRVLLAGDAAHI
                     HPPTGGQGLNLGVQDAFNLGWKLAATVNGWAPEGLLDTYHAERHPVAARVLVNTRAQIT
                     LLGSEPGPTALRELFSKLMDFEEVNRYVTGMITGVDVRYDLGDGHDLVGRRMRDLRLKR
                     GRLYELTHDGRGLLLDRGGALSVEGWADRVDHVVDTAEDLDAPAVLLRPDGHVAWAGED
                     QRELLDGLARWFGAATG"
     gene            5123..5743
                     /locus_tag="K1J60_RS43340"
                     /old_locus_tag="K1J60_43340"
     CDS             5123..5743
                     /EC_number="2.3.1.-"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013005987.1"
                     /locus_tag="K1J60_RS43340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K1J60_43340"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_220651016.1"
                     /transl_table=11
                     /translation="MTLPPAVRPYRPGDLDAVHDICVRTAHNGGDSRPVHADPDVFPAT
                     FATPYTHLEPELTFVLDDGRGRAVGYILGTADTPAFVEEFRAKWLPLVTERFPAPVGPD
                     TSPDAAIVRLLHHPERMLLPELLPYPAHLHIDLLPAWQGRGHGRALMRTFLHALRTRGV
                     PAVHLTMLTSNTPARAFYDRLGFHEIEVPDPGPVTCLGRSTGE"
     gene            complement(5775..6443)
                     /locus_tag="K1J60_RS43345"
                     /old_locus_tag="K1J60_43345"
     CDS             complement(5775..6443)
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013005993.1"
                     /locus_tag="K1J60_RS43345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K1J60_43345"
                     /product="response regulator transcription factor"
                     /protein_id="WP_220651017.1"
                     /transl_table=11
                     /translation="MTTVLIADDQPLQRLGFRMLLQGTPGLTPVGEAEHGAEAVRLAAR
                     LRPDVVLMDIRMPGMDGLEATRRIVAAGGRTRVLIVTTFDLDEYAYDGLRAGASGFLLK
                     DARPEELVAGIHAVATGDAVVAPSLTRRLLDAYAHQVLAPSGTPLPPDPRLRTLSEREH
                     EVLVAIGQGWTNTEIAERLVLTESTVKKHVGRVLAKIGARDRVQAVIMAYDAGLVRAKP
                     "
     gene            complement(6445..7824)
                     /locus_tag="K1J60_RS43350"
                     /old_locus_tag="K1J60_43350"
     CDS             complement(6445..7824)
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013005994.1"
                     /locus_tag="K1J60_RS43350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K1J60_43350"
                     /product="sensor histidine kinase"
                     /protein_id="WP_220651018.1"
                     /transl_table=11
                     /translation="MSPHRATPAAETTPGTVLAPSPGYDAAWHPVLGRMLHGQRRRQLL
                     DRRHPWLLDTAVVLVVALISLPDLLMDHGGDGGPFGETEYRTDLPAAVPFLFAALLVVP
                     LWWRRRAPAVTFFVIAAVSLVQWSLDVWQQAGLSMLVALYSLALHGSLRVLGWAVVVTA
                     GELSLAVWLLGRVEHPLLGLFFLLGTATAAVTLGLTLRIRRMYLATLEDRAARLEIERD
                     QRVRLTAAAERSRVAREMHDIVGHNLSVMVSVADGAAVLAAGRGEGSAEALRILGDTGR
                     QAMGELRRVLDVLREDQDDERLLAPQPGIPDLDALLARVRAAGLPVTYRTVGDLDALGG
                     GVQLTVYRIVQEALTNTLKHAGTGATAEVGVTAEAAGTVHVRVADTGVAADGPGRAEPG
                     RTGADEPDEPGHGLVGIRQRAAMYGGAVTIGPRDSGHGWIVDVLLDVPPAPPTLSPRES
                     I"
     gene            complement(7897..8727)
                     /locus_tag="K1J60_RS43355"
                     /old_locus_tag="K1J60_43355"
     CDS             complement(7897..8727)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020123432.1"
                     /locus_tag="K1J60_RS43355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K1J60_43355"
                     /product="ABC transporter permease"
                     /protein_id="WP_220651019.1"
                     /transl_table=11
                     /translation="MTTTDLSVVPARTRVHQVTGRRVLRSEWAKFWSLRSSWITLGVAL
                     VLLVLFGTIAGYTYSPDATGAEGPPGPGSGGDAVALALTGVTFASLAVGVLGVLLSAGE
                     YSTGMIRSTLAAVPRRLPVLWAKSAVIGVIALILSTVGALAAFQLGAPGLDGERISLSL
                     GDDGVLRGLAGAGVYLALVAVAGVALGVLLRSSAGAIAALVGILLVLPGLATLLPDSWY
                     DTITPYLPSNAGSAIYALTESAGSLSPGQGLAVFAGWVALALAGAAHRLVRTDA"
     gene            complement(8727..9656)
                     /locus_tag="K1J60_RS43360"
                     /old_locus_tag="K1J60_43360"
     CDS             complement(8727..9656)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009713469.1"
                     /locus_tag="K1J60_RS43360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K1J60_43360"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_220651020.1"
                     /transl_table=11
                     /translation="MIEARELTKRYGDKTVVDRLSFTVRAGEVTGFLGPNGAGKSTTMR
                     MIIGLDSPTGGTVTVNGRSYARHSAPLHEIGSLLEAKSVHPGRTAFNHLMALAHTHGIG
                     RRRVDEVIELAGLTSVAGKRVGAFSLGMGQRLGIAAALLGDPAVVMLDEPVNGLDPEGV
                     LWVRNLLRRLADEGRAVMLSSHLMSETALIANHLVIIGRGRLLADTTVDGFVRDAGGGG
                     VKVATTEPLKLRSLLAGPDVTISSTTTEELIVTGLDAREIGAIAARHGVPLHELTPQAV
                     SLEEAFMQLTAEAVEYQSALAEPARKAA"
     gene            complement(10001..10339)
                     /locus_tag="K1J60_RS46530"
     CDS             complement(10001..10339)
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012705.5"
                     /locus_tag="K1J60_RS46530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="squalene/phytoene synthase family protein"
                     /protein_id="WP_259408182.1"
                     /sec_met_domain="phytoene_synt (E-value: 4.1e-08, bitscore:
                     31.8, seeds: 8, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPVASLLGPEADGGRFRAACRTLMEGSRRLDFVNDLAEDLPEGRL
                     GIPAEALARFSVTVEDLAAGRTSAGLRELVEDQVEAARSACERPANCPCSGKVPAGCSW
                     TRASGSSC"
     gene            complement(10655..11692)
                     /locus_tag="K1J60_RS43370"
                     /old_locus_tag="K1J60_43370"
     CDS             complement(10655..11692)
                     /EC_number="3.2.1.-"
                     /GO_function="GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA]"
                     /GO_process="GO:0071704 - obsolete organic substance
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005474166.1"
                     /locus_tag="K1J60_RS43370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K1J60_43370"
                     /product="glycoside hydrolase family 5 protein"
                     /protein_id="WP_220651021.1"
                     /transl_table=11
                     /translation="MPRKNHRGTACLAASLAGVTAFGGVLASPASAAATFRHASPPPVS
                     DFRGVNWADPRDNYADDAVVPSGLSTTDTYATTYAKSRAIVGGFAELGANTVRLPVNPT
                     SVNGPFWTSYRAAIDAATAKGFKVILGYWEADNAKDGKIDDQASWDRMWARITSAYGRN
                     GKVYFEPMNEPFGYTSQEWRDVAARWLATHRSIPRDRVLIGGIKYSEDVKPVCADSRLD
                     GTRIALHNYGFWHTDWTSVDQWKADFKERIGSCASRTVLDEFGASMTTGLDYNGPVNGS
                     NEVAYIQAATDTIRELGLGSVYWPGLRNGDTYSLTTLQGTGTRLSLKVNNQSGLDRLHW
                     AWKQK"
     gene            complement(11828..13078)
                     /locus_tag="K1J60_RS43375"
                     /old_locus_tag="K1J60_43375"
     CDS             complement(11828..13078)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015507623.1"
                     /locus_tag="K1J60_RS43375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K1J60_43375"
                     /product="DUF2993 domain-containing protein"
                     /protein_id="WP_220651022.1"
                     /transl_table=11
                     /translation="MRSPHRTDPHQMSDDRSDAPRNPYEELGALDDGPLEVTSLEEFFD
                     EDTTGRGGEEEQEPQWAPPVHRRGGRRRRGRFAGLPLAVKAVVGLVVLAAFAGLADRWA
                     VLYAEHRAADALEDRLDLAAAPEVEIGGFPFLTQLAHKRLDSVRLTVPDVAADRVSLAK
                     VSATAHDIRLDAEGLTTMRGAHVPRLDGDVLLSFADLNRELGASQVKFTGEGRDRVRAR
                     GTLPVAGRDLRLRAEATIQRQGERGIATEIGGMRLDIGDVATYRPGTRASDGLHLTPKA
                     SAELARETRRAKALLSVPAIVRRLGMSDAAAREALADEGELAELTGSPRFARRAQSLNL
                     IDLALENPAVLRALGIDADLLDALSRLTRPALADRLSLSFELPEPERGNVRLRDVRVEE
                     DGIRVRLTGSQLAFGDR"
     misc_feature    13131..13146
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: weak, score: 15.73"
                     /tool="antismash"
     misc_feature    13300..13315
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 17.33"
                     /tool="antismash"
     gene            13308..14636
                     /locus_tag="K1J60_RS43380"
                     /old_locus_tag="K1J60_43380"
     CDS             13308..14636
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004004084.1"
                     /locus_tag="K1J60_RS43380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K1J60_43380"
                     /product="cytochrome P450"
                     /protein_id="WP_220651023.1"
                     /sec_met_domain="p450 (E-value: 6.7e-63, bitscore: 212.0,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDTEAGPGSLPHAPATGWPVPEAEPGLVARWRSDGGELLDLLTLV
                     RERLGGVAAFRLGPTPTVLVTDPQAVRHVLALRPERYVKRSHRARLLIGDGVLAADGAA
                     WKRQRRLLQSQFTGPGMRRYEQRITAAARTTSARWETYARTGQTFDVGQEMRRFALDTI
                     WRSLTGHPLDDETQRELAAVETVGAALPTLPADAGEARDAVADDLARIDAVARRAIDAA
                     RGGAAGPHGPGLLHVLTDASTEHPEYTDQLIRDEFVTLLAAGHETTATTLTWLHLLLDR
                     HPEARAQALAAGDEGSTERRQAVQALIHETLRLYPSAWILARHAAEDDVLAGHLIEAGS
                     DLLVCPYLTHRDPALWPDPERFDPRRFTSPGGRPTHPGAYFPFGIGPRACLGLQFALRE
                     ATVLLERLLPHAPVFHSVPPKAVHGITVRPDGPTPAGLKPPRD"
     gene            complement(14665..15315)
                     /locus_tag="K1J60_RS43385"
                     /old_locus_tag="K1J60_43385"
     CDS             complement(14665..15315)
                     /GO_function="GO:0008237 - metallopeptidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016805 - dipeptidase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010357311.1"
                     /locus_tag="K1J60_RS43385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K1J60_43385"
                     /product="M15 family metallopeptidase"
                     /protein_id="WP_220651024.1"
                     /transl_table=11
                     /translation="MSEIILMNDPRVAGVPVHESDEPLVDMRELSFLRVDARLADPAGT
                     YALLREGAAWRLARAARLLPEGLRLLVTEGYRPLALQQSHFERYVAELRASHPDWSESY
                     LRSRASRSLSPPELGPHVAGAAVDLTLCTTAGAELDLGTPVNASPEENDGACRTSAADI
                     TATARRNRRTLSAALTTAGLTHHPTQWWHWSYGDRYWALRTGAQAALYGPADA"
     gene            complement(15427..16143)
                     /locus_tag="K1J60_RS43390"
                     /old_locus_tag="K1J60_43390"
     CDS             complement(15427..16143)
                     /GO_function="GO:0004040 - amidase activity [Evidence IEA]"
                     /GO_function="GO:0042834 - peptidoglycan binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF017102.5"
                     /locus_tag="K1J60_RS43390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K1J60_43390"
                     /product="CHAP domain-containing protein"
                     /protein_id="WP_220651025.1"
                     /transl_table=11
                     /translation="MSSTIKIDTTKPAAAGSSARRAAALLLISALAGGALTAEAASAAT
                     ASPRSSSAAAAVSLQSAIKTKAQQQVNLSPRNREMAGNCNYYSAVATAPKSGSVGNCKK
                     VGGLQWRTNNWCADFVRYVWKNAGARQKGTDAFAGSFYRARKSIGTWHARGSYVPKVGD
                     AVLYDWDGGTPSLGNNGWDVDHIGIVIGYNPKTKALTTVEGNTTRKGNGGTEGVYQRTR
                     YNTKAGDVVGYVTPKK"
     gene            complement(16236..19598)
                     /locus_tag="K1J60_RS43395"
                     /old_locus_tag="K1J60_43395"
     CDS             complement(16236..19598)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1041:
                     transcriptional regulator, SARP family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020115420.1"
                     /locus_tag="K1J60_RS43395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K1J60_43395"
                     /product="BTAD domain-containing putative transcriptional
                     regulator"
                     /protein_id="WP_259408183.1"
                     /transl_table=11
                     /translation="MSLEYRLLGPVEVWSGGRRLPLGGPKPRALLAALLLRPGRVVSAG
                     TLIDTVWGDEPPDSARALVQTYVSGLRRALPAGAEGIETRPPGYLLRVDGDRDRLDLRD
                     FERLTAAGRDRAAIGDHRGASELLGQALELWRGSALGGVGRALRVEAERLEEARQAALE
                     DRISADLAAPGREQHLVAELTALVGTHPTRERLRGHLMLTLYRLGRQADALAAYAEGRA
                     VLADELGIDPGPALRQLHEAILRSDPGLMPPTAPARERPSRTEGPPHPAPGSPDRAGVA
                     HRPRSVGHPESAQPLDDAQRLGDPDRLASPHRPAAVHRPGPVHHTDGSRRPDPARRPDG
                     SRPHPSSVGSVGDAGSPGGPAPTRSGPLPRAALLPPAIGDFTGREGQLAEVSALLTGRR
                     DAMPVAVVSGPGGVGKSAFAVQVAHRVAADYPDGQLYAELHGFSDPVPPAEVLARLLRA
                     MGTEPPEGPAERGDLFRSLLARRRVLLVLDDAGSEAQVRPLLPGGASCGVLITSRARLA
                     GLDGAARTGLDVLDAELGSELLARIAGDEHVRSDPDAARRIVALCGGLPLALRIAGARL
                     ATRRHWTPRMLADRLADERRRLDELTVGDLEVRTGLGLSYDALDAPGRTALRRLGLLGA
                     PDVAVWTVAALLDLPDTEDAENVVDRLIDAQLLHFTGVDRAGQPRFGLHDLVRVYAAER
                     AEAEEPRAERAAALGRALGAWLWLTARATAAGPSGEVVLQDPSTLWPVGERAAEQVLAD
                     PTAWFEAEAGAIAAAVERAAAMDLHALAREAAVTLCSSAYIVNSRFDSWSRTHEAALAA
                     VRRAEDRAGEALLLIGLGQLRYEQDDFTESVDHYRQAVRLCAELGDTRGHAAALAGLGG
                     TYREQGRLRDAARELTRAIDDFGRLDDTAGLGLACRLAGSVHLELGEYATARVLVDESL
                     AAYRRLGSRRGEALALRTYGLLHRALGEYAAAEELSGQALAILQRFGDRLMSAYAAQAR
                     AKARLRLGRTREAAADLAGLLDVCRAYGDRWGEALLRRTLGECATAEGRFTEAEAHLTE
                     SVALWDILRLPLPRARTLRSLAELRDRLGDEKGARALWEEAVEVFTAYEVHEARESLQE
                     GPSRTSRRPEGKL"
     misc_feature    complement(16962..16964)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(18891..18893)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(19709..19727)
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 20.86"
                     /tool="antismash"
ORIGIN
        1 cgtccgtgta cagcaccagc gtggacctcg gcgggagcgg agtgagcgtg tcggtgcgag
       61 cccgggtcag gcccgtgccg agcagatggt cgtgttcctc gtccaggaac cgggacctgc
      121 cgtcgtgcgt gatcagcagc ggcggcggat gccccgcgtt ggtccaccgc agggcccagg
      181 cgtcgtcgct gcgctcgacg cggccgaaga tcagcgtcgc catggacgcc tcggtcacgt
      241 tcaccacggc ctggtccagc cgctccacga tcgcgctcgg cggctccttc agcgcccagg
      301 cgtaggcccg gagcatgttg cgcacctgcg ccatcccggc cgccgcgtcg atgttgtgtc
      361 cgacgacgtc cccgacggcc accgccgtgg acccgtcggc cagcgagaag gcgtcgtacc
      421 agtcgccgcc gacctgggag gacttcgacg ccgactcgta acgcgccgcc attcgcagcc
      481 ccggcacctc cggcatctgg ggcagcagat ggcgctgcat ggtctccgcg atgtgccgct
      541 gccgctggta caggcgcgcg ttctccagcg ccagcccggc ccggcgggcg atgtcgtcca
      601 acagcgacag ctccgcctcg gtgaaggccc ccggccgctc gctcaggccc agcgtgagag
      661 cgccgagcac cgcgcgcggt ccccggatgg gcgcgatggc cgccgagcgc agccccgtct
      721 cctcgaacag tttctgctgg gcgaccgtga tccccgagtc cgccggccct tggtaggtct
      781 ccgggccgac cagggtcgag gccgccccgc gcagggcccg ggacagcggc atgagggact
      841 cctcgtgcac cggcgggagc ggcccctcca actcctcgcg ccgcaccacc acgccgtcac
      901 ggtgggtcac caccatggtc cgccagacgt cgtcgctctc ggtgatcagg tccacgacgg
      961 cccagtccgc cagccgtggc accaccagcc gcaccaggcg ggcgaccgtc tcctcggcgt
     1021 ccagggtgga actcagccgg gtggtcgtct cggcgagcag cgccagccgg tccaactgcg
     1081 acagcgccgg cgacgcgccg tccgcgacga caccgctctc cggggcgcac tcgtggaaga
     1141 ggaccagcgc gccggtcgcg gtcccgtcga gcctgcacgg ggtcaccagc caggtcaccg
     1201 gcagcagcgt gccgtcgccg cgcaggaacc actccaggtc cccaccgccc gtacggccac
     1261 tgaggaacgc gtgcatcatc gagcacgccg cccgcggaat cgtctgcccg agccggtccc
     1321 ggtgcagcag ttcgtgggcg tcccgcccga cgagtccgtc ggccgggcgg cggagcaact
     1381 ccgccgccct tgggttcacc gcgacgacga gtccgttgtc gtccaccacg tacataccgg
     1441 cgtgcacgag atcgggcacc ccgttcggtg agcgcaccac cggacccggc gaccgccgtt
     1501 cggtgtgatc cggactccac gcgctcatgc tcgggttcct ccgactccgg tcgcggacgg
     1561 gacggtcgta gacgtcgacg gtcggtaccg ccgcatgtgc tgcacgcatt accccgtccc
     1621 cgacgaccta cgcgcaccag gtcccggacc gcaggtggga gcgggttgtc ggaccccggg
     1681 caccgccgcg cgccacgcac ggacggcgac gccccggaca cggtcggcac atcgcgcgcc
     1741 cggtcggccc ggggcccgcg gagcggacgg atccgccggg gtcaggcctg ggtgtgccgt
     1801 acgcaggcgg cgacgacctc gcgcaggctc cccgtccgag ccatcacctc gcgctgcacc
     1861 cgggccccgt tgccgcgccc cgtcagcgcg gcgacggcgt cccgggccag gtcggcgtcc
     1921 ccgtggtcga cgagggcccc ctcgacgtgg tggagcagtg agcggatcac gtcgagggcc
     1981 ggccggggcc gcatcgtgac ggggtccagg aggttctccg acatcccgga gcgggcggcc
     2041 cgccaggtgg ccagccgcag cagtcccgca ctgtggccga gcggctccac accggcccgc
     2101 cactcccggg ccgcggtctc cacgagcccc cgggcgaggg ccgcgacgag gaccgcggtg
     2161 tcggggtgca gacagacgtc cgcgacccgg atctcgacgg tcggataccg ctgggacagc
     2221 cgtgcgtcga agtagaccat gccctggtcg cgcacgactc ccgtggcgat cagatccgtg
     2281 acgcactggt ggtaccgctc ggccgagccg aagacgtccg tcggcccggc catcggccac
     2341 atgtcccaca cctggctgcg gtagctggcg taccggctgt cgtagccctg ccagaaggga
     2401 gagttcgcgc tcagcgccgt cagcacggac agccagggcc gcatccggtc caggacggcc
     2461 acgccctcgt cgtcggactc gacggacaca tggacgtggc agccgcagac cagttgcacc
     2521 tgcgtgtgca ggccgaactc ccgcgccatc caccggtacc ggctgttcat ggtgatcgtc
     2581 ggactcaccg gcagcggcga cgtcgccagc gccacgaccg cgctgccgag cccctcggca
     2641 tgacgggccg cgtccttgcg gcagcggacg atctcggccc ccagatcggt catcgaggac
     2701 tgcgggtggg tggcgaactc cacctgctcg tcgtgcagct ccttctcgaa cacatcctgg
     2761 tccgtgccct ccagcgcggc tcgcgcgagc accgccgcgg cccgcgcctg cggctcgccg
     2821 gtctgcggat cgaccaggag gagttcctct tccactccga cggtacgcac gtcatccggc
     2881 ccttctgcgc taggtggtga gagccgtgtg cccccggacg aggccgggac acctcaacgg
     2941 acggcgtgcg aaccggttcc gtgtacgcgg cggcggcccg ggtacccgtg cggcgtcccg
     3001 ggagccgcgc cgggcgggcg cggattcgcc gtccgcgaca cggaggagaa cgtgaacagc
     3061 accaccgaga cgggccacgt gaccggtacc gcggacaagg actacaacct gatccggtac
     3121 gtcgaggcct gcctcgacaa cgcgctgcgc ctcgagtcgt acatccagga cgcggagcgg
     3181 gagaaggaca ccgaggtggt cgaactgttc cgcaaggcac aggccgacag ccgcaagggc
     3241 gccgacctcg gcaaggaact cctgcgccgg cgtccgagcg gctgacggcg ctcccgggcc
     3301 gcgcgcggtc cgggtgaaca tcgcacgctc cgttcccggc acagcgccat tgtgggcacg
     3361 gtccgggttg tcacgcgaac cggagggcgg gcacggcggg ccccggcgcg accggagacg
     3421 accagggcga aggccccaca gagacgagaa cgacaaaggc aaggaggtca tgtcctcctt
     3481 gcctgtctca acgtatagcg caccgggggg cttgcggcaa gaccctcccc ctgccgcaga
     3541 atcgccgacc gaggcgagaa gcagcggcac atccgcgcac atggggggtt gagatgatcg
     3601 acgtgatcgt cgtcgggggc ggaccgaccg ggttgatgct ggcgagcgag ttgcggctgg
     3661 ccggggtggg cacggtggtg ctggagaggc tgaccgagcc gaccggcgag tcccgggggc
     3721 agggcctgca cgcgcgaagt gtcgaggtga tggaccagcg cggcctgctg gaccggttcc
     3781 tcgcggtcag tgagaagttc cgggtcggcg gcctcttcgg cggcatcatg aagccgtggc
     3841 cggaaagcct ggacacggct cacgcgtacg gcgtggccac cccgcagccg gtcaccgagc
     3901 gcatcctcca ggagcgcgcc ctggaactcg gcaccgacat ccggcgcggc agcgaactgg
     3961 tggggctcga ccaggacgag gacggtgtga ccgcgcgact ggcggacggc acgcgattgc
     4021 gcgcccgcca tctcgtcggc tgcgacgggg gccgcagcgt ggtgcgcaag ctgctcggcg
     4081 tcggtttccc cggcgagccc gccaccgtcg agaccctgct gggcgacatg ggggcgaccg
     4141 aggacccggc gacgatcgcc gcggtcgtgg aggaggtccg caggacccag ctgcggttcg
     4201 gcctcgcccc tctcggggac gggaactacc gcgtgctcgt acccgccgag ggggtgtccg
     4261 aggaccgtac gacccagccg accctggacg agttcaagca gcggctccgc gccttcgcgg
     4321 gcaccgactt cggtgtccac tcaccacgct ggctctcccg gttcggcgac gccacccggc
     4381 aggccgagcg ctaccgggtc ggccgggtgc tgctggccgg cgacgcggcc cacatccatc
     4441 cgccgaccgg cggccagggg ctcaacctcg gtgtgcagga cgccttcaac ctgggctgga
     4501 agctggctgc cacggtcaac ggctgggcgc cggaggggct gttggacacc taccacgccg
     4561 agcggcaccc ggtcgccgcc cgcgtgctgg tcaacacccg cgcgcagatc accctgctgg
     4621 gttccgagcc ggggccgacc gcgctgcggg agctgttctc gaagctcatg gacttcgagg
     4681 aggtgaaccg gtacgtgacc gggatgatca ccggggtcga cgtccgctac gacctcggcg
     4741 acggtcacga cctggtcggc cggcggatgc gggacctgcg gctgaagcgg gggcgtctgt
     4801 acgagctgac gcacgacggc cgcggcctgc tgctcgaccg cggtggcgcg ctctcggtgg
     4861 agggctgggc ggaccgggtc gaccacgtgg tggacaccgc cgaggacctg gacgcgcccg
     4921 cggtcctcct gcggcccgac ggccacgtgg cgtgggccgg cgaggaccag cgggaactgc
     4981 tcgacggact cgcccggtgg ttcggggcgg ccacgggctg agcggcggcc gaggggcggg
     5041 cgcgcgggga gcgtgtgccg catcggccgg cggcatcgct caggcggttg tgggggccgc
     5101 cgacaccgcg caggatgctg cgatgaccct gcctcccgca gtccgcccgt accggcccgg
     5161 ggacctcgac gccgtccacg acatctgtgt ccgtaccgcc cataacggcg gcgacagccg
     5221 tcccgtccac gccgaccccg acgtcttccc ggcgacgttc gccacccctt acacccatct
     5281 cgaaccggag ctgaccttcg tcctggacga cggccgcggc cgggcggtcg gctacatcct
     5341 cggcactgcc gacacccctg ccttcgtcga ggagttccgc gcgaagtggc tgcccctggt
     5401 gaccgagcgc ttcccggcgc ccgtcggtcc ggacacctcc cccgacgcgg cgatcgtccg
     5461 gctcctgcac caccccgagc gcatgctcct ccccgaactc ctcccgtatc cggcccactt
     5521 gcacatcgac ctcctccccg cctggcaggg ccgcggccac ggccgggccc tcatgcgcac
     5581 cttcctccat gccctgcgca ccagaggggt cccggccgtc cacctcacca tgctcacctc
     5641 caacacgccg gcccgcgcct tctacgaccg tctgggcttc cacgagatcg aggtaccgga
     5701 ccccggcccg gtgacctgtc tcggccgttc gactggggag tgacaggccc tgtgcgccgg
     5761 ctcatgcccg ggcgtcaggg cttcgccctc accaggcccg cgtcgtaggc catgatcacg
     5821 gcctggacgc ggtcgcgggc gccgatcttg gcgaggacgc ggccgacgtg tttcttcacg
     5881 gtggactcgg tgaggacgag acgttcggcg atctccgtgt tggtccagcc ctggccgatg
     5941 gccacgagca cctcgtgctc gcgttcgctg agggttcgca gccgggggtc gggcggcagg
     6001 ggcgtgccgc tcggggcgag gacctggtgg gcgtaggcgt cgaggagccg acgggtcagg
     6061 ctgggggcga cgacggcgtc cccggtggcg accgcgtgga tgccggcgac gagttcctcg
     6121 gggcgcgcgt ccttgaggag gaagccgctg gcgccggccc gcagcccgtc gtacgcgtac
     6181 tcgtcgaggt cgaaggtggt cacgatgagg acgcgggtgc ggccgccggc ggcgacgatc
     6241 cggcgggtcg cctccaggcc gtccatgccg ggcatacgga tgtccatgag gaccacgtcg
     6301 gggcgcagcc gcgcggcgag gcggacggct tcggcgccgt gctcggcctc cccgaccggg
     6361 gtgaggccgg gggtgccctg gaggagcatg cggaagccga ggcgttgcag gggctggtcg
     6421 tcggcgatca gcacagtggt catgtcagat gctctcccgg ggcgacaggg tgggtggcgc
     6481 ggggggtacg tccagcagga cgtccacgat ccagccgtgg ccggagtcgc gtgggccgat
     6541 ggtgacggcg ccgccgtaca tggcggcccg ctgccggatg ccgaccagtc cgtgccccgg
     6601 ctcgtcgggt tcgtcggccc ccgtccgccc cggctccgcc cggcccggcc cgtccgccgc
     6661 cacgccggtg tcggcgaccc ggacgtgcac ggtgccggcg gcctcggcgg tcaccccgac
     6721 ctcggccgtg gcgcccgtac cggcgtgctt gagggtgttg gtcagggcct cctgcacgat
     6781 ccggtacacg gtgagctgca caccgccgcc cagcgcgtcg agatcgccca cggtccggta
     6841 ggtcacgggc aggcccgccg cgcggacccg cgccaacagg gcgtccaggt cggggatgcc
     6901 cggctgcggt gcgagcagcc gctcgtcgtc ctggtcctca cggaggacgt ccagcacgcg
     6961 gcgcagttcg cccatggcct ggcggccggt gtcgccgagg atgcgcagag cttcggcgga
     7021 cccctcgccc cggccggcgg cgaggaccgc ggcgccgtcc gcgacgctga ccatgacgga
     7081 gaggttgtgg ccgacgatgt cgtgcatctc gcgggccacc cgggaacgct cggcggcggc
     7141 ggtgagccgg acacgctggt cgcgttcgat ctccagccgg gcggcgcggt cctccagcgt
     7201 cgccaggtac atcctgcgga tccggagggt caggcccagg gtgacggccg ccgtggccgt
     7261 gcccagcagg aagaacaggc cgagcagcgg atgctcgacc cgccccagga gccagaccgc
     7321 gagggacagt tcaccggcgg tcacgacgac cgcccagccc agcacccgca gcgaaccgtg
     7381 cagggccagg ctgtacaggg cgacgagcat gctgagcccg gcctgctgcc acacgtccag
     7441 cgaccactgg accagtgaca ccgccgcgat gacgaagaac gtcacggccg gcgcccggcg
     7501 tcgccaccac agcgggacga ccagaagggc cgcgaagagg aacgggacgg ccgccgggag
     7561 gtcggtgcgg tactccgtct ccccgaaggg gccgccgtcg ccgccgtggt ccataaggag
     7621 gtcgggcagg ctgatcagcg ccacgaccag caccaccgcc gtgtcgagca gccaggggtg
     7681 ccgccggtcc agcagctgcc gtcggcgctg tccgtgcagc atccggccca ggaccggatg
     7741 ccaggcggcg tcgtaccccg gggacggcgc gaggacggtc cccggggtgg tctccgcggc
     7801 gggtgtcgcg cggtgcggac tcatgggcct cattgtcctc ggttctcgga ggcggttgtc
     7861 cgtgctcccg gccgtgcggg tgccgggtcc ggcaggtcag gcgtccgtcc ggaccagtcg
     7921 gtgggccgcc cccgccaggg ccagcgcgac ccagccggcg aagaccgcga gcccctgccc
     7981 gggggagagg gagccggcgg actcggtcag ggcgtagatc gccgatcccg cgttgctggg
     8041 gaggtacggg gtgatcgtgt cgtaccagga gtccggcagc agcgtggcga gcccggggag
     8101 gacgagcagg atgccgacca gagccgcgat ggctcccgcg gaggagcgca gcagcacccc
     8161 cagggccacc ccggccacgg cgaccagagc gaggtagaca ccggctccgg ccaggccgcg
     8221 cagcacgccg tcgtcgccca gggagagcga gatccgctcc ccgtccaggc cgggagcgcc
     8281 gagctggaag gcggccagcg cgccgaccgt gctgaggatc agagcgatca ccccgatgac
     8341 ggcgctcttc gcccagagca ccggcagccg gcgcggcacc gcggcgagcg tggagcggat
     8401 catgccggtg ctgtactcgc ccgccgacag cagcaccccg agcacgccca ccgccagcga
     8461 cgcgaaggtc acgccggtca gcgccagcgc gaccgcgtcg cccccggagc ccggtccggg
     8521 cggtccctcg gcaccggtgg cgtcgggact gtaggtgtag ccggcgatcg tcccgaagag
     8581 gaccagcagc accagggcca ccccgagggt gatccaactg gagcgcagcg accagaactt
     8641 ggcccactcc gagcgcagca cccggcggcc ggtcacctgg tgcacccggg tacgggcggg
     8701 gaccacggac agatcggtgg tggtcatcag gcggcctttc gcgcgggctc ggcgagagcg
     8761 ctctggtatt cgacggcttc ggcggtgagt tgcatgaagg cctcctccaa ggagaccgcc
     8821 tggggggtga gttcgtgcag gggtaccccg tgccgggcgg cgatcgcccc gatctcccgg
     8881 gcgtccagcc cggtgacgat cagttcctcg gtggtggtgg agctgatcgt gacgtccggc
     8941 ccggccagca gcgagcgcag cttcaacggc tcggtggtgg cgaccttcac gccgccgccg
     9001 cccgcgtccc ggacgaagcc gtccacggtc gtgtccgcca gcagccgccc ccgcccgatg
     9061 atgaccaggt ggttggcgat cagcgcggtc tcgctcatca ggtgcgagga gagcatcacg
     9121 gcccgtccct cgtcggcgag gcggcgcagg aggttgcgca cccacaacac accttccgga
     9181 tcgaggccgt tgaccggctc gtcgagcatc accaccgccg ggtcgccgag cagggcggcg
     9241 gcgatgccga gccgctgccc catgccgagc gagaaggccc ccacccgctt gccggccaca
     9301 ctggtcagcc cggccagctc gatcacctcg tccacccggc ggcgcccgat gccgtgggtg
     9361 tgcgccagcg ccatcaggtg gttgaacgcg gtccggccgg ggtggaccga cttggcctcc
     9421 agcagcgagc cgatctcgtg cagcggcgcc gagtgccggg cgtaggagcg tccgttgacg
     9481 gtgaccgtgc ccccggtggg ggagtccaga ccgatgatca tgcgcatggt cgtggacttg
     9541 cccgcgccgt tcgggcccag gaagccggtc acctcaccgg cccggacggt gaagctcagc
     9601 cggtcgacca ccgtcttgtc cccgtaccgc ttcgtcagct cacgcgcttc gatcatggca
     9661 gtgggcccct tctcgctcgc ctcggacggg gccgcgattc ctcccgcgac ctctgcctgc
     9721 gaacctatga gcgccgccgg ccgagcccct gggaccgcgg gggacacttc ggcccgccac
     9781 tggtaccggg gtaccactgg tgtgtcctac ctcggtatcg accggacacg acgatcggca
     9841 cccgcaggag cgatctgccc tcgggtgccc gcggtgcggc tgccgcgctc ctcgcgagcc
     9901 cgtcggcgag cgctcagcgg cacccgcagg gtgcccgcca ccggcgggga cgcggaaccg
     9961 cgcaacagcc gggtgccacg ggcggacccc gcgcccgcgg tcagcagctc gatcctgatg
    10021 cccgagtcca ggagcacccc gccgggacct tccccgagca ggggcagttc gcgggccgct
    10081 cgcaggcaga ccgggccgcc tctacctggt cctccaccaa ctcccgcagg cccgccgacg
    10141 tccggcccgc cgcgaggtcc tcgacggtga ccgagaagcg tgccagcgcc tcggccggga
    10201 tgcccagacg gccttccggc aggtcctcgg ccaggtcgtt gacgaagtcc agccgccggc
    10261 tgccctccat gagcgtccgg cacgccgccc ggaaccgtcc gccgtcggcc tccgggccca
    10321 gcagcgacgc caccggcatg aacgcgggca gcgcagaggc gccacgcagg cctggcagta
    10381 ggcctcggtg gcgaagcccg tgaactccgg atcggtggtg gcggtggaca ggtgctcctc
    10441 gaccgtctcc cgcagccgtg gatacgccgc cgtggtgtgc agcggagcgc gagatcagga
    10501 cgctgatgcg cccccgggga agtcggcggg tctctcgccg cgcgagaccc gccgttcgtt
    10561 cggccgtcgt gccttcgagt ccgggcggac acggcgcggg agccgcccga catcgatgtc
    10621 gtgacggctc cccggagtgt cgtgcggggt gccgctactt ctgcttccag gcccagtgca
    10681 gccggtccag gccgctctgg ttgttcacct tcaggctcag acgggtgccc gtgccctgga
    10741 gggtggtgag ggagtaggtg tcaccgttgc gcagccccgg ccagtagacc gagcccaggc
    10801 ccagttcccg gatggtgtcg gtcgcggcct ggatgtaggc gacctcgttg gagccgttga
    10861 ccgggccgtt gtagtccagg cccgtggtca tggaggcgcc gaactcgtcg aggactgtgc
    10921 gcgaggcgca gctgccgatg cgctccttga agtcggcctt ccactggtcg acgctggtcc
    10981 agtcggtgtg ccagaagccg tagttgtgca gggcgatccg ggtgccgtcg agccggctgt
    11041 cggcgcagac cggcttgacg tcctcgctgt acttgatgcc gccgatgagg acccggtcgc
    11101 gggggatcga gcggtgggtg gccagccagc gcgcggcgac gtcgcgccac tcctgcgagg
    11161 tgtagccgaa cggctcgttc atcggctcga agtagacctt gccgttgcgg ccgtacgcgg
    11221 aggtgatgcg cgcccacatg cggtcccagg aggcctggtc gtcgatcttg ccgtccttgg
    11281 cgttgtcggc ctcccagtag cccaggatga ccttgaagcc cttggcggtg gcggcgtcga
    11341 tcgcggctcg gtacgacgtc cagaacgggc cgttcacgga ggtggggttc accggcaggc
    11401 ggaccgtgtt ggcacccagc tcggcgaacc cgccgacgat cgcccgtgac ttggcgtacg
    11461 tcgtggcgta ggtgtcggtg gtggacagtc ccgagggcac gaccgcgtcg tcggcgtagt
    11521 tgtcgcgcgg gtcggcccag ttgacgccgc ggaagtcgct gaccggtggc ggcgaggcgt
    11581 ggcggaaggt ggcggcggcg gacgcggggg aggcgaggac cccgccgaat gccgtgacgc
    11641 cggccagcga tgccgcgagg caggctgtcc cgcgatggtt ctttcgtggc accagttccc
    11701 tttctgggca gttgcgtccg cgaaacccgg ctgtgcaggt cggcggctct gtggctcccg
    11761 caacgtagaa gagatctcga acagaggtca acacatctgc acaccaagtt tcatcaagaa
    11821 cgcagaatca cctgtcgccg aaggccagtt gcgacccggt gagccggacc cggatgccgt
    11881 cctcctccac gcgtacgtca cgcagccgca cgttcccgcg ctcgggttcc ggcagttcga
    11941 aggagaggga cagccggtcg gcgagggcgg gccgggtgag ccgggacagg gcgtcgagga
    12001 ggtcggcgtc gatgcccaga gcgcgcagta cggcggggtt ctccagggcc agatcgatga
    12061 ggttgaggct ctgggcccga cgggcgaagc gcggggatcc ggtcagttcg gcgagttcgc
    12121 cctcgtcggc gagggcctcg cgggcggcgg cgtccgacat tcccagccgc cgtacgatcg
    12181 ccggcaccga cagcagtgcc ttcgcccttc gggtctcccg ggcgagttcg gcggaggcct
    12241 tcggtgtcag atgcagaccg tccgaggcgc gcgtgccggg gcggtacgtg gcgacgtccc
    12301 cgatgtccag gcgcatgccg ccgatctccg tggcgatgcc ccgctcgccc tgccgctgga
    12361 tcgtggcctc ggcgcgcagc cgcagatcac gtccggcgac cggcagggtg ccacgcgccc
    12421 ggacccggtc acggccctcg ccggtgaact tcacctggga agcgccgagt tcgcggttga
    12481 gatcggcgaa ggacagcagt acgtcgccgt cgagacgcgg aacgtgggcg ccgcgcatgg
    12541 tcgtgagacc ctcggcgtcc agccgtatgt catgggccgt cgccgacacc ttcgccagcg
    12601 acacccggtc ggccgcgacg tccggcacgg tcagccgcac cgagtccagc cgcttgtggg
    12661 cgagttgggt gaggaagggg aaaccgccga tctccacctc gggcgccgcg gccaggtcca
    12721 gccggtcctc cagggcgtcc gcggcccggt gttccgcgta cagcaccgcc caccggtccg
    12781 cgaggccggc gaacgcggcg agaacgacca gtcccacgac cgccttcacc gcgagcggca
    12841 gcccggcgaa ccgtccccgg cgccgccggc cgccccgccg atgcaccggc ggagcccact
    12901 gcggctcctg ctcctcctcg ccgccgcgtc cggtggtgtc ctcgtcgaag aactcctcca
    12961 gggaggtcac ttccagagga ccgtcgtcga gggcgccgag ctcctcgtag gggttgcgcg
    13021 gcgcgtcgga gcgatcgtcg gacatctgat gcggatctgt gcggtggggg gagcgcatcg
    13081 cctcatccga acatgtccac cacccccgcc cgcaacctga accccgcgta tgcgatgtag
    13141 ttcacgatcg cgacgagggg tggcgaaggc agccgaccgc gggcacgagc gggagctgac
    13201 cttctgtcac gggcggtgcc cgttcccgta cagtccgtgc tgcgagaatg tggtgcgcgg
    13261 ccgacccggc ggtcgagggg ccgagcgggc gatcaggggg tagacacatg gacaccgaag
    13321 ccggtcccgg ctctcttccg cacgctcccg cgacggggtg gcccgtcccg gaggccgagc
    13381 cggggctggt ggcgcggtgg cggtcggacg gcggtgaact gctcgatctg ctgacgctgg
    13441 tgcgtgaacg gctcggcggg gtcgcggcgt tccgcctcgg gccgactccc accgtcctcg
    13501 tcaccgaccc gcaggcggtc cggcacgtcc tcgccctgcg gccggagcgc tacgtcaaac
    13561 gctcgcaccg cgcccggctg ctgatcggcg acggtgtcct ggccgccgac ggtgcggcgt
    13621 ggaagcggca acgccgactg ctgcagtccc agttcaccgg tcccgggatg cgccgctacg
    13681 agcagcggat caccgccgcc gcccgcacca cctcggcacg ctgggagacg tacgcacgca
    13741 ccgggcagac cttcgacgtc ggccaggaga tgcgccgctt cgccctggac accatctggc
    13801 gttccctcac cggccacccc ctcgacgacg agacgcagcg cgaactggcg gccgtggaaa
    13861 ccgtgggggc cgccctgccc accctgcccg ccgacgccgg cgaggcccgg gacgccgtcg
    13921 ccgacgacct cgcacggatc gacgcggtcg cccggcgcgc catcgacgcc gcccgcggcg
    13981 gcgcggcggg cccgcacggt ccgggactgc tgcacgtgct gaccgacgcc tccaccgagc
    14041 accccgagta caccgaccag ctgatccgcg acgagttcgt caccctgctg gcggccggac
    14101 acgaaaccac cgccaccacc ctgacctggc tccacctgct cctcgaccgg cacccggaag
    14161 cacgcgcaca ggcactcgcc gccggagacg agggttccac ggagcgccgc caggcggtcc
    14221 aggccctgat ccacgagacg ctccgcttgt atccgtccgc ctggatcctg gcccgccacg
    14281 ccgccgagga cgacgtcctg gccggtcacc tcatcgaggc gggctccgac ctcctggtct
    14341 gcccgtacct cacccatcgc gaccccgccc tgtggccgga ccccgagcgc ttcgaccctc
    14401 ggcgcttcac ctccccgggc ggccgcccca cccacccggg cgcgtacttt cctttcggta
    14461 tcgggccccg cgcctgcctc ggcctccagt tcgcactgcg cgaggcgacc gttctcctcg
    14521 aacgactgct gccgcacgcc ccggtcttcc actccgtgcc cccgaaggcc gtccacggca
    14581 tcacggtccg ccccgacggc cccacgcccg ccggcctgaa accgccacgg gactgagggg
    14641 ccgcctctac cggcccgccc gggctcaggc gtcggccggg ccgtagaggg ccgcctgcgc
    14701 gccggtgcgc agggcccagt accggtcgcc gtaggaccag tgccaccact gcgtggggtg
    14761 gtgggtgaga ccggccgtgg tgagcgcggc ggacagcgta cggcggttgc ggcgggcggt
    14821 ggcggtgatg tccgcggcgg acgtgcggca ggcgccgtcg ttctcctcgg ggctcgcgtt
    14881 caccggagta cccaggtcga gttcggcgcc cgcggtggtg cacagggtca gatcgacggc
    14941 ggcgcccgcg acgtgcgggc cgagctccgg cggcgacagc gaacggctcg cccgggaccg
    15001 cagatacgac tcggaccagt cggggtgcga ggcgcgcagc tcggccacgt accgttcgaa
    15061 gtggctctgt tgcagggcga gggggcggta gccctccgtg accagcaggc gcagtccctc
    15121 ggggagcagc cgggcggcac gcgccagccg ccacgcggcc ccctcgcgca gcagggcgta
    15181 ggttcccgcc ggatcggcga gccgggcgtc gacgcggagg aaggacaact cccgcatgtc
    15241 caccaggggt tcatcggact cgtggaccgg gacgccggcc acgcgggggt cgttcatgag
    15301 gatgatctct gacatctcag tcctgtgggg aggtggcgcg tcgcaccgag acgcccccgg
    15361 ggccggtccg acgaccggcc ccgggggctc ccccgtggat gcctggctct cgtagcccgt
    15421 cgcccgctac ttcttgggcg tcacgtagcc gacgacgtca ccggccttgg tgttgtaccg
    15481 ggtgcgctgg tagacgccct cggtaccgcc gttgcccttc ctggtggtgt tcccctcgac
    15541 ggtcgtcaga gccttggtct tggggttgta gccgatgacg atgccgatgt ggtcgacgtc
    15601 ccagccgttg ttcccgaggc tcggcgtacc gccgtcccag tcgtagagca ccgcgtcgcc
    15661 gaccttcggg acgtaggagc cccgggcgtg ccaggtgccg atggacttgc gggcccggta
    15721 gaaggagccg gcgaaggcgt cggtgccctt ctggcgggcg ccggcgttct tccagacgta
    15781 gcggacgaag tcggcgcacc agttgttggt gcgccactgc agcccgccga ccttcttgca
    15841 gttgccgacc gacccgctct tcggggcggt ggcgacggcg ctgtagtagt tgcagttgcc
    15901 ggccatctca cggttgcgcg gcgagaggtt cacctgctgc tgcgccttgg tcttgatggc
    15961 gctctggagc gagaccgccg ccgcggcgga ggacgaccgc ggtgacgccg tcgcggccga
    16021 ggccgcctcc gcggtcagcg ctccgcccgc gagggccgag atcagcagca gagcggcggc
    16081 acgtcgtgcc gacgacccgg ccgcggcggg cttggtggtg tcgatcttga tggtgctgga
    16141 catcggaagt cctttccccg tggaatcccc gttggtgccg gggagttcgg gtggctcccg
    16201 ttcccctccg acaccaagaa gcttcgccgg gccctctaca acttcccttc aggtcttctt
    16261 gacgtcctcg agggcccttc ttgaagcgac tcccgtgcct cgtgcacctc gtacgcggtg
    16321 aacacctcca cggcctcctc ccacagggcc cgcgccccct tctcgtcacc gaggcggtcc
    16381 cgcagttccg cgagggagcg cagggtgcgg gcccggggca gcggaagccg caggatgtcc
    16441 cagagggcga cggactcggt gagatgggcc tccgcctcgg tgaaccgccc ctcggccgtg
    16501 gcgcattcgc cgagggtgcg ccggagcagt gcctcacccc agcggtcgcc gtacgcccgg
    16561 cacacgtcga gcaggccggc caggtccgcc gccgcctccc gggtgcgtcc gagcctgaga
    16621 cgtgccttcg cacgggcctg cgcggcgtac gcgctcatca gacggtcgcc gaaccgctgg
    16681 aggatcgcca gggcctgccc ggagagttcc tcggccgccg cgtactcgcc gagcgcgcgg
    16741 tgcagcaggc cgtacgtccg cagggcgagc gcctcgccac gccggctgcc gagtcggcgg
    16801 taggcggcca gggactcgtc gacgaggaca cgggcggtgg cgtactcgcc gagttcgaga
    16861 tggaccgacc cggcgagacg acaggccagg ccgagcccgg cggtgtcgtc gagccgtccg
    16921 aagtcgtcga tggcacgggt gagttcgcgc gccgcgtccc gtaaccggcc ctgttcgcgg
    16981 taggtgccgc ccaggcccgc gagggccgcc gcgtggcccc gggtgtcgcc gagttcggca
    17041 cacaaccgga cggcctgccg gtagtggtcc acggactcgg tgaagtcgtc ctgctcgtag
    17101 cggagttggc cgaggccgat gagcagcagc gcctccccgg cccggtcctc ggcgcgacgt
    17161 acggcggcca gcgcggcctc atgggtacgc gaccacgagt cgaagcggct gttgacgatg
    17221 taggcggacg agcacagggt gaccgcggcc tcgcgggcga gggcgtgcag atccatggcg
    17281 gcggcccgct cgacggcggc ggcgatcgcc ccggcctccg cctcgaacca cgcggtcggg
    17341 tcggccagca cctgttcggc ggcccgctcg ccgaccggcc acagggtgct cgggtcctgg
    17401 agcaccacct ccccggaggg ccccgcggcc gtcgcccgtg cggtgagcca cagccaggcg
    17461 cccagcgcac gcccgagggc ggcggcccgc tcggcgcgcg gttcctccgc ctcggcccgc
    17521 tcggcggcgt acacccggac caggtcgtgc agtccgaagc gcggctgccc ggcccggtcg
    17581 acaccggtga agtgcagcaa ctgcgcgtcg atgagccggt ccacgacgtt ctcggcgtcc
    17641 tcggtgtccg gcaggtccag cagcgcggcc accgtccaaa cggccacgtc gggcgcgccg
    17701 agcagaccga ggcgccgcag ggcggtacgg cccggggcgt cgagtgcgtc gtagctgagc
    17761 ccgaggccgg tacgcacctc caggtcgccg acggtgagtt cgtcgaggcg gcggcgttcg
    17821 tcggcgagtc ggtcggcgag catgcgaggt gtccagtggc ggcgggtggc gaggcgggcc
    17881 cccgcgatgc gcagggccag cggcagtccg ccgcagaggg cgacgatgcg gcgcgccgcg
    17941 tcggggtcgc tgcgcacgtg ctcgtctccg gcgatcctgg cgagcagttc gctgcccaac
    18001 tcggcgtcca ggacgtcgag tccggtgcgg gccgcgccgt cgaggcccgc cagccgggca
    18061 cgggaggtga tcagcacccc gcagctcgcg ccgccgggca gcagcggccg tacctgcgcc
    18121 tcgctgcccg cgtcgtcgag gaccagcagc acccgacgtc gggcgagcag actgcggaac
    18181 aggtcgccgc gttcggcggg gccctcgggc ggctcggtgc ccatcgcgcg cagcagccgc
    18241 gccagcacct cggcgggtgg caccggatcg ctgaagccgt gcagttccgc gtagagctgg
    18301 ccgtcggggt agtcggcggc gacccggtgc gcgacctgga cggcgaacgc cgacttcccg
    18361 acgccgccgg gcccggagac gaccgcgacc ggcatcgcgt cacgccgacc ggtcaacagg
    18421 gccgatacct cggcgagttg cccttcccgg ccggtgaagt cgccgatggc gggcggcaga
    18481 agggcggccc gcgggagggg accggaccgc gtcggagccg gaccgcccgg gctgccggca
    18541 tcgccgacgg accccacgga agagggatgc ggccgggagc cgtcgggacg gcgggcggga
    18601 tcgggacggc gggagccgtc ggtgtggtga acgggtccgg gcctgtggac ggcagccggt
    18661 cggtgcgggg aagcgagccg gtcggggtca ccgagacgct gggcgtcgtc gaggggctgg
    18721 gcggactccg ggtggcccac ggaacgcgga cggtgtgcga cgcccgcccg gtcggggctg
    18781 cccggggccg ggtggggcgg tccctccgtc cggctgggcc gttcccgcgc cggggcggtg
    18841 ggcggcatca gccccgggtc cgaccgcagg atcgcctcgt gcaactgacg taacgccggt
    18901 ccagggtcga tgcccagttc gtcggcgagt acggcgcgtc cctccgcgta cgccgcgagc
    18961 gcgtcggcct ggcggcccag ccggtagagc gtgagcatca gatgcccgcg cagccgttcg
    19021 cgcgtggggt gggtgccgac cagcgccgtc agctcggcga ccaggtgctg ttcgcggccc
    19081 ggtgcggcga ggtcggcgga gatccggtcc tccagggcgg cctgacgcgc ctcctccaac
    19141 cgctcggcct cgacacgcaa cgcccggccc actccgccga gggccgatcc acgccacaac
    19201 tccagcgcct gtcccagcag ttcggaggcg ccccggtgat caccgatggc cgcccggtcg
    19261 cgccccgccg ccgtgagccg ctcgaagtcc cgcaggtcga gccggtcccg gtcgccgtcc
    19321 acccgcagca gatagccggg cgggcgcgtc tcgatcccct cggctccggc tggcagagcg
    19381 cgccgcagtc cggagacgta cgtctgcacg agcgcgcgtg cggagtccgg tggctcgtcg
    19441 ccccagaccg tgtcgatcag tgttccggcg gagaccaccc gccccggccg cagcagcaac
    19501 gcggccagca gcgcgcgggg tttgggcccg ccgagcggaa gacggcgtcc accggaccag
    19561 acttccaccg ggccgagcag tcggtactcc aggctcacgg ggcccccgtt tccagcgttg
    19621 cgcgtgcatg ccacatgttg gcggctcggc atcgtacgca tccggtatac ggggggtcac
    19681 ggaggacatg cgagtctctt ccagacctgt tgcggttccg tcgcatccgg aaagctgccc
    19741 ccccaccccg gcaagggccc cgacgcgcga attcggcacg gactcgcctg cggcctcggc
    19801 ccgtggcccg ggtcgagggc gtagcctgcg gcgggccgac gcctgacgag gagccgctcg
    19861 tgaccacccc tgaagcgacg agaccccacc cgcgcaactc gggcctgcgg gtcgacctca
    19921 acccggccgc cgccgtcgca cgcaacgccc gctaccaggg ttcctctgtc gtcatccgct
    19981 atccgggcgg tgacctcacc tacgccgaac tcgacgaccg ggccgcccgc ctggccaccg
    20041 tcctggcgca cggcggcacc ggtgacggag accgggtcgc ccacctcggc ctcaacagca
    20101 gttccttcct cgtcaccctg ctggccgccc accggctcgg ggccgtcttc gtcccggtca
    20161 acttccgtct ggcggtggcc gagttggagg ccgtcctcgt ccgctgcggc gccaccgccc
    20221 tcgtctgcga ggagggacac cgcgacatgg tcgacgagat ccgcgaccgg accgccctca
    20281 cgcggttcct cctggtggac gacgaccccg aggcgccgac cgcgggggcg gcgggctgg
//
