LOCUS       NZ_CP080647            20615 bp    DNA     linear   CON 08-NOV-2024
DEFINITION  Streptomyces akebiae strain MG28 chromosome, complete genome.
ACCESSION   NZ_CP080647
VERSION     NZ_CP080647.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces akebiae
  ORGANISM  Streptomyces akebiae
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Kitasatosporales; Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 10257202)
  AUTHORS   Ping,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2021) College of Life and Environment Science,
            Hunan University of Arts and Science, No. 3150 Dongting Avenue,
            Changde, Hunan 415000, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. v. 3
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 120.0x
            Sequencing Technology             :: Oxford Nanopore PromethION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_019599145.1-RS_2024_11_06
            Annotation Date                   :: 11/06/2024 09:26:18
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 9,127
            CDSs (total)                      :: 9,036
            Genes (coding)                    :: 8,727
            CDSs (with protein)               :: 8,727
            Genes (RNA)                       :: 91
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 309
            CDSs (without protein)            :: 309
            Pseudo Genes (ambiguous residues) :: 0 of 309
            Pseudo Genes (frameshifted)       :: 142 of 309
            Pseudo Genes (incomplete)         :: 231 of 309
            Pseudo Genes (internal stop)      :: 20 of 309
            Pseudo Genes (multiple problems)  :: 77 of 309
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 03:57:32
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 9638316
            Orig. end                         :: 9658931
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP080647.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Mo Ping.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..20615
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="linaridin"
                     /region_number="31"
                     /rules="(cypemycin or cypI)"
                     /tool="antismash"
     cand_cluster    1..20615
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(cypemycin or cypI)"
                     /kind="single"
                     /product="linaridin"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20615
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:10615](-)"
                     /cutoff="20000"
                     /detection_rule="(cypemycin or cypI)"
                     /neighbourhood="10000"
                     /product="linaridin"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..10615)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cypemycin or cypI)"
                     /neighbourhood="10000"
                     /product="linaridin"
                     /protocluster_number="1"
     gene            complement(93..1073)
                     /locus_tag="K1J60_RS41730"
                     /old_locus_tag="K1J60_41730"
     CDS             complement(93..1073)
                     /GO_function="GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019068993.1"
                     /locus_tag="K1J60_RS41730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K1J60_41730"
                     /product="fibronectin type III domain-containing protein"
                     /protein_id="WP_259408150.1"
                     /transl_table=11
                     /translation="MRRVSVPALVLVPTLCGPLLLTAGCAVRERPGSLPPPAPPGVTAD
                     AGSATSVHVMWNRAPGDTEIAGYEVYRGRAKVKDVPGDEHMVDITRLRPSTTYVFTVRA
                     RGASGDLGPPSAEVRATTPAAGTADRRAPSRPGRPDGKVLGSRTVQLSWGPSTDDRDVV
                     SYDILQGGSKVHGVGGEQTAAVVTGLRPGTRYSFTVRARDAADNVSPVSATARLTTAPG
                     ADDGRGTAPTGLRAATRRDERAYSVELSWLPPPVDGVVTEYEIQLDGRPATTLVWGGTP
                     PRGRATYRFHVGLEAGVTYRVRIRAKLPDGTWGGFSAERTVTTAG"
     misc_feature    complement(1108..1123)
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 20.6"
                     /tool="antismash"
     gene            1474..2202
                     /locus_tag="K1J60_RS41735"
                     /old_locus_tag="K1J60_41735"
     CDS             1474..2202
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020114654.1"
                     /locus_tag="K1J60_RS41735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K1J60_41735"
                     /product="glycoside hydrolase family 75 protein"
                     /protein_id="WP_220650763.1"
                     /transl_table=11
                     /translation="MRVRSLTLAAVGAALLAPVALPALAHPQRPVQYEGGVTAADLLAR
                     ARGCVRVSEGLYSSDAGKPAEIPVCGVDGAVYWKADMDIDCDGRPSPRCNRETDPWFQP
                     ATSFLQSDGRYLRSESLPFVVVPAPSRVWDYRVHGIKGGSVAAVVHGDRVEYAVVGDTG
                     PQNIIGEASYATAEALGIRPDPRTGGTASGVTYIVFEDTEVTPIEDHQAAVELGGKLAR
                     KWVEGAVMRRGATMRGGATN"
     gene            complement(2465..2875)
                     /locus_tag="K1J60_RS41740"
                     /old_locus_tag="K1J60_41740"
     CDS             complement(2465..2875)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005474594.1"
                     /locus_tag="K1J60_RS41740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K1J60_41740"
                     /product="PTS-dependent dihydroxyacetone kinase
                     phosphotransferase subunit DhaM"
                     /protein_id="WP_220650764.1"
                     /transl_table=11
                     /translation="MSEEKRVGIVLVSHSAAVAASVAELARGLAGAGAFVPVAPAGGTE
                     DGGLGTSAELISAAAASVDRGAGVAVLTDLGSAVLTVKALLAEGDELPADTRLVDAPFV
                     EGAVAAVVTASTGADLTAVAAAASEAYTYRKE"
     gene            complement(2868..3482)
                     /gene="dhaL"
                     /locus_tag="K1J60_RS41745"
                     /old_locus_tag="K1J60_41745"
     CDS             complement(2868..3482)
                     /EC_number="2.7.1.121"
                     /GO_function="GO:0047324 - phosphoenolpyruvate-glycerone
                     phosphotransferase activity [Evidence IEA]"
                     /GO_process="GO:0006071 - glycerol metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="dhaL"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005474593.1"
                     /locus_tag="K1J60_RS41745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K1J60_41745"
                     /product="dihydroxyacetone kinase subunit DhaL"
                     /protein_id="WP_220650765.1"
                     /transl_table=11
                     /translation="MLDADFFRRWMTATAASVEREAERLTELDSPIGDADHGSNLHRGF
                     TAVAAVLEKEAPDTPGAVLVLAGRQLISTVGGASGPLYGTLLRRTGKALGDAAEVSEAQ
                     LTDALRAGVDAVMTLGGAAPGDKTMVDALVPAVDALAESFAAARAAAEEGASATTPLQA
                     RKGRASYLGERSIGHQDPGATSAALLIAALATTADTEAADV"
     gene            complement(3572..4564)
                     /gene="dhaK"
                     /locus_tag="K1J60_RS41750"
                     /old_locus_tag="K1J60_41750"
     CDS             complement(3572..4564)
                     /EC_number="2.7.1.121"
                     /GO_function="GO:0004371 - glycerone kinase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006071 - glycerol metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="dhaK"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018546231.1"
                     /locus_tag="K1J60_RS41750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K1J60_41750"
                     /product="dihydroxyacetone kinase subunit DhaK"
                     /protein_id="WP_220650766.1"
                     /transl_table=11
                     /translation="MKMLINVAESVVADALRGMAAAHPELTVDVENRVVVRRDAPVAGK
                     VGLVSGGGSGHEPLHGGFVGPGMLSAACPGEVFTSPVPDQMVRAAAAVDSGAGVLFIVK
                     NYTGDVLNFDMAAELAADEGIRIAKVLVDDDVAVTDSLYTAGRRGTGATLFVEKIAGAA
                     AEEGQPLEQVEALARQVNESSRSFGVALSACTTPAKGSPTFDLPAGELELGVGIHGEPG
                     RERRAMMTSREIADFAVNAVLDDMSPRNPVLLLVNGMGATPLLELYGFNAEVQRALTER
                     GVAVARTLVGNYVTSLDMAGASVTLCQVDEELLRLYDAPVRTPGLRWGV"
     misc_feature    4547..4562
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 17.67"
                     /tool="antismash"
     misc_feature    4549..4563
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 21.52"
                     /tool="antismash"
     misc_feature    complement(4550..4565)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 17.26"
                     /tool="antismash"
     misc_feature    4919..4932
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.28"
                     /tool="antismash"
     gene            5396..5578
                     /locus_tag="K1J60_RS41755"
                     /old_locus_tag="K1J60_41755"
     CDS             5396..5578
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="K1J60_RS41755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="K1J60_41755"
                     /product="hypothetical protein"
                     /protein_id="WP_220652009.1"
                     /transl_table=11
                     /translation="MELARGLAVFGMYAAHLGPDPSEGGTTGFLVEQFSARPVGIIGAA
                     ATAPNGDLHQATLTP"
     gene            complement(5808..6764)
                     /locus_tag="K1J60_RS41760"
                     /old_locus_tag="K1J60_41760"
     CDS             complement(5808..6764)
                     /NRPS_PKS="Domain: Abhydrolase_1 (22-128). E-value:
                     3.5e-31. Score: 100.6. Matches aSDomain:
                     nrpspksdomains_K1J60_RS41760_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1036: alpha/beta hydrolase fold protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020121719.1"
                     /locus_tag="K1J60_RS41760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K1J60_41760"
                     /product="alpha/beta fold hydrolase"
                     /protein_id="WP_220650767.1"
                     /sec_met_domain="PF00561 (E-value: 8.2e-25, bitscore: 86.9,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 1.8e-20, bitscore:
                     73.5, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVAHRMIEANGVRLHIAEQGAGPLVVLLHGFPESWYSWRHQFDPL
                     AAAGFRVVAPDQRGYGDSDRPEAVEAYTILHLVGDVVALIRALGEEKAYVVGHDWGAPV
                     AWHTALLRPDMVLGVAGLSVPPPFRGKQPPLVAAQERYGGRFYWNYFNRPGVADAEFAE
                     DPRTTLRKIFYWASGDARVTGEDRQPLVDPERGWLTTLADPEALPEWFTEDDLDVLTES
                     FSRGFTGALNWYRNLDRNWELTAPWHHARVTPPALFVYGDRDLVPAFPGTPELIAALPD
                     LMPSLRGEPVELPGCGHWTQQERPDEVNAALVDFLTG"
     aSDomain        complement(6381..6698)
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_K1J60_RS41760_Abhydrolase_1.1"
                     /evalue="3.50E-31"
                     /label="K1J60_RS41760_Abhydrolase_1.1"
                     /locus_tag="K1J60_RS41760"
                     /protein_end="128"
                     /protein_start="22"
                     /score="100.6"
                     /tool="antismash"
                     /translation="PLVVLLHGFPESWYSWRHQFDPLAAAGFRVVAPDQRGYGDSDRPE
                     AVEAYTILHLVGDVVALIRALGEEKAYVVGHDWGAPVAWHTALLRPDMVLGVAGLSVPP
                     PF"
     gene            complement(6832..7695)
                     /locus_tag="K1J60_RS41765"
                     /old_locus_tag="K1J60_41765"
     CDS             complement(6832..7695)
                     /EC_number="2.1.-.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1248: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019435955.1"
                     /locus_tag="K1J60_RS41765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K1J60_41765"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_220650768.1"
                     /transl_table=11
                     /translation="MSTSTTSTTSVTLTKTPTAGATTRTGTATRTTTTGIVDDIGYGRQ
                     FDGWYHRLFPDDASVVAEVDLLASLHPDPATGTVEFGVGNGRIALPLSRRVGRITGVDS
                     SPEMLALLRRDLTEETPVEPVHADIRTYTADGTVGLVYAICATLSMLLTPEEQQQAVRR
                     AADLLAPGGRLVVETHNKPAVLALHEGRARATYFTPYPEPGTGLQSHSLLFPEGSLWHL
                     SHVWYESDGTTRVGTEVSRLTAPEEFDAYARAAGLEPERRWGDWPADAAPYGPDSPLAI
                     CSYVKP"
     gene            complement(7692..7883)
                     /locus_tag="K1J60_RS41770"
                     /old_locus_tag="K1J60_41770"
     CDS             complement(7692..7883)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005474572.1"
                     /locus_tag="K1J60_RS41770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K1J60_41770"
                     /product="hypothetical protein"
                     /protein_id="WP_220650769.1"
                     /transl_table=11
                     /translation="MNDFLLIPFVVALGIVGFLITTRAVSTPAVLGVALVVLLGACSQA
                     RRNAHPRTTPPKKRRHHP"
     gene            complement(7942..9834)
                     /locus_tag="K1J60_RS41775"
                     /old_locus_tag="K1J60_41775"
     CDS             complement(7942..9834)
                     /EC_number="7.-.-.-"
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005474570.1"
                     /locus_tag="K1J60_RS41775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K1J60_41775"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_220650770.1"
                     /transl_table=11
                     /translation="MSDLPAGRGRHTRPQDPPVNLAKEGGPGGGRRAGHRAVPQLNLHL
                     LWGEGAKPWRAMGRHRRLVLLGIFLGLVGAGTSLAQPAVIGQLVGAVGEGRSVTGPILV
                     GAALFIADAALGALHSYVIGLAGENIVYDIRRTLASRLLRSRFKAYSGLQQGDVFSRMV
                     SDTMLARSTMTHAIDSILNNSFLVIGGIALMAWIDTVLLAATLACLGVTSAVSLWLARG
                     VRRVSVLNQADLGTFGSALLRVLGAMPTVKASRAESREAEGIAAIARRARKSGIKVTVM
                     SSLLDPTMSIGTQLALTVVIGLGAARTATGAMPTADLTAFILYLFYLVAPLLTLFESIA
                     QFQIGRASVDRLAELGRIEVETDAVGGPSAERPRGVRPLRRDYEPGLRFDGVRFSYPGS
                     DKMVLDGVSFSVPPGGLTAIVGPSGGGKSTLFQLIERLFDPVSGAIRIDGTDITDLPLN
                     QLRSIVGYVDQDHTLLRGTVRENLTYSAPDADDKDIAEALRMANLTEVIAALPHGLDTE
                     LGDRGAGLSGGQRQRLAIARTLLQAPRFLLLDEATANLDTESENALRDSIAMISGFCAV
                     IAIAHRLSTVTEAQQIVVLDRGRVHAVGTHDELHRHSDLYRRLARLQALSDVAS"
     gene            complement(9874..9999)
                     /locus_tag="K1J60_RS46490"
     CDS             complement(9874..9999)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="K1J60_RS46490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_259408151.1"
                     /transl_table=11
                     /translation="MDFAIPFILLAMLIFALGLLKAGLRIRRSQAEAKEEGREHE"
     gene            complement(10001..10615)
                     /locus_tag="K1J60_RS41780"
                     /old_locus_tag="K1J60_41780"
     CDS             complement(10001..10615)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     linaridin: cypI"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005474565.1"
                     /locus_tag="K1J60_RS41780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K1J60_41780"
                     /product="hypothetical protein"
                     /protein_id="WP_259408369.1"
                     /sec_met_domain="cypI (E-value: 6.8e-31, bitscore: 106.4,
                     seeds: 22, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPRRLPLKNPFTGEGAAWRIAGAAMLVVTFAGQHPFEQFSRFRTK
                     DVLSLVPNWRFFAPNPCMHDSHFLYRTVDAEGNASPWRDGFTTETRKPQHIVWFPTRRA
                     DKGVSDACADILPTLEFGGFEAASRVPGYRMVTEHLRLLIRSQGLAADEVRGFQFALAR
                     ATGFDTRHRPELMFVSPFVPLDPQAPGTPLTSAPAKTPAKV"
     gene            complement(10618..12537)
                     /locus_tag="K1J60_RS41785"
                     /old_locus_tag="K1J60_41785"
     CDS             complement(10618..12537)
                     /NRPS_PKS="Domain: Abhydrolase_1 (355-471). E-value:
                     1.5e-10. Score: 33.1. Matches aSDomain:
                     nrpspksdomains_K1J60_RS41785_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013005805.1"
                     /locus_tag="K1J60_RS41785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K1J60_41785"
                     /product="alpha/beta fold hydrolase"
                     /protein_id="WP_220650772.1"
                     /sec_met_domain="PF00561 (E-value: 2e-07, bitscore: 29.9,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKLVRRITSAVPDKVASAVLGPIPVGRDRALGLSERLAAATSLTS
                     SLEYLSQRHEMDKGGMNDWDIAKDSVAHANPLLRRVIDIASGRRTTTALHVTRAAVASA
                     MLLPGRSPWRGAGSLFLGATSALLGPRQHYGSDGADQVATLVQLATGGARLVPSPAAKD
                     ALMWYVALQSNLSYLVSGWVKLLGPDWRDGSALPGVMRTHTYGHEGMHTWIRNNPRAAK
                     LLAHSVLALECLFPLAYLKGGRLTRPVLASAAAFHLANGYFMGLGRFATAFPAMHPLIA
                     YTAAPRTHPAVAGRDDRALPAALTLLAGATAAAGVTAVHRRMRATEGWRTSRVLTTRHG
                     NRLQYEEMAAGDADRPVFVLAAGLLSTSEHYAWISERLAYETSYGVITYARAGYAGSHR
                     RATTAYRLTESVDDLVDLVNGAVAPHRKVVLVGHSIGGELARRAVTHLGDRVHGVVYLD
                     SSHPDQFHRSAQQRVTGAGLGSTFTSMSRALRLGTGALLTRPWWIKELPAAYQDKVFAQ
                     YSDARMWEAARREWTALREDFEAFPGRLAPIEGVPCLVISAQRTVDRDPEQLLMHRELA
                     EAHRGAPTETVVIEGAGHDTLLINSRYAHQVTDRVLAFFHNLDERPRAARSTRSVTLRK
                     EASR"
     aSDomain        complement(11125..11472)
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_K1J60_RS41785_Abhydrolase_1.1"
                     /evalue="1.50E-10"
                     /label="K1J60_RS41785_Abhydrolase_1.1"
                     /locus_tag="K1J60_RS41785"
                     /protein_end="471"
                     /protein_start="355"
                     /score="33.1"
                     /tool="antismash"
                     /translation="PVFVLAAGLLSTSEHYAWISERLAYETSYGVITYARAGYAGSHRR
                     ATTAYRLTESVDDLVDLVNGAVAPHRKVVLVGHSIGGELARRAVTHLGDRVHGVVYLDS
                     SHPDQFHRSAQQ"
     misc_feature    complement(12537..12551)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.69"
                     /tool="antismash"
     misc_feature    12560..12575
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 19.63"
                     /tool="antismash"
     misc_feature    12567..12576
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: medium, score: 17.13"
                     /tool="antismash"
     gene            complement(12653..12922)
                     /locus_tag="K1J60_RS41790"
                     /old_locus_tag="K1J60_41790"
     CDS             complement(12653..12922)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005474562.1"
                     /locus_tag="K1J60_RS41790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K1J60_41790"
                     /product="hypothetical protein"
                     /protein_id="WP_259408152.1"
                     /transl_table=11
                     /translation="MSSIENALNSVEIPVEGVVYVAARPTLGTPRIARIGRIAQAAEGV
                     GALAAAATAAVGVAQAAEANNLAAEANAQNQAALAAVGGTPPAV"
     misc_feature    complement(13018..13033)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.77"
                     /tool="antismash"
     gene            complement(13142..14572)
                     /locus_tag="K1J60_RS41795"
                     /old_locus_tag="K1J60_41795"
     CDS             complement(13142..14572)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013005807.1"
                     /locus_tag="K1J60_RS41795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K1J60_41795"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_220650773.1"
                     /sec_met_domain="DAO (E-value: 1.3e-08, bitscore: 33.8,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTAVVVGSGPNGLAAAVFLAREGVDVTVLEAADTIGGGTRTSEL
                     TPGLLHDHCSATHPMAVASPFLRDLDLGRHGLTWCLPEIDCAHPLDSGEAGVLHRSVQE
                     TADGLGGVDGRRWQRLFGPLADGFDALAEDLMLPLPHVPRHPLRLAAFGSRALLPTVAV
                     ARLWRSPAARALFAGVAAHAFRPFHLPAGAAVGLTIVAAGHRHGWPVAAGGSRAISDAL
                     AAQLFEFGGRIETGVKVCASADLPPADVVLFDLAPRAVADILGDRLPGRVARAYRRFRH
                     GPGAFKADFAVEGGVPWTNEAARRAGTVHLGGTFEEVAHTERMIQAGRMPERPFVLVGQ
                     QYLADPSRSKGDLHPVWTYAHVPHGYDGDATEAIIGQIERFAPGFRERVLDMAVRPPAA
                     FADYNPNYVGGDVVTGANTALQLVMRPRVALDPYRTGVPGMYICSAASPPGAGAHGMCG
                     ANAAASALRHLRRRHGRE"
     gene            complement(14819..16165)
                     /locus_tag="K1J60_RS41800"
                     /old_locus_tag="K1J60_41800"
     CDS             complement(14819..16165)
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013005808.1"
                     /locus_tag="K1J60_RS41800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K1J60_41800"
                     /product="sensor histidine kinase"
                     /protein_id="WP_259408153.1"
                     /transl_table=11
                     /translation="MTTSSLAALSARATQPHHHGRPRLPARRLDHRALYPALGVLWLLD
                     VGIIVSQQRGPLDWLPLVTGPVALALVLVPESRLSITWRTGFCAAVSTTVTLGTSLMGW
                     AMPEWGLLETACMLVLLARTCRHVARPRVALALAAAMGASVIDEPLRTGGTSITLTYPF
                     LLTFAVGGAIGAGCYLRTLDARRRRTIAAVRLAERIQLARELHDFVAHHVTGIIAQAHA
                     AGVVHESAPHQVGPILGNIAEAGQRTMDSMRRLIRVLREDGEQVSLERPEEPYAELAKL
                     VSEFSDQGDGSTAQLEITGAARRSGLLPEVGSAVHRVVQEALTNVRRHAPGTQATVRVH
                     RTRDDLLRVDVYNEGPERRVSRPTGGRGGYGLIGLRERVETVGGSLTAGPADDGGWWII
                     AHFPVLPPAVLPGAEDAAGSGPGSRRQPGRHAKPNAHAEPEPDMSWDAS"
     misc_feature    complement(16094..16096)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(16265..16954)
                     /locus_tag="K1J60_RS41805"
                     /old_locus_tag="K1J60_41805"
     CDS             complement(16265..16954)
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005474556.1"
                     /locus_tag="K1J60_RS41805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K1J60_41805"
                     /product="response regulator transcription factor"
                     /protein_id="WP_220650774.1"
                     /transl_table=11
                     /translation="MLGRVSHTPTRVMIADDQDLIRAGFRLILDAQEGIEVIGEAADGL
                     ACVELARALRPDVCLVDVRMPKLDGLEVTRLLAGPGATHPTQVVVVTSFDQDDYLNVAL
                     RNGACGFLLKDAAPALLIEAVRAAARGDALVSPAVTVRLLKQLEERAAVPVDGVGVPES
                     SLSARELEVARLVAVGRTNQEISDELCLSLSTVKTHLGHIHHKLGVRNRVEVAAWAWAN
                     GTVRTGR"
     misc_feature    17133..17148
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: strong,
                     score: 19.52"
                     /tool="antismash"
     gene            17210..17512
                     /locus_tag="K1J60_RS41810"
                     /old_locus_tag="K1J60_41810"
     CDS             17210..17512
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1197:
                     autoinducer-binding transcriptional regulator,"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013005810.1"
                     /locus_tag="K1J60_RS41810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K1J60_41810"
                     /product="response regulator transcription factor"
                     /protein_id="WP_220650775.1"
                     /transl_table=11
                     /translation="MALDSSGRLSAREMEILLLAAHGMSDADMSRQLSISVRTVASHMR
                     SIREKLCAKNRTHLVVTALRAGILALRTDRMDRLDETFRLTGRSGVRPPRPVGIA"
     gene            complement(17694..18815)
                     /locus_tag="K1J60_RS41815"
                     /old_locus_tag="K1J60_41815"
     CDS             complement(17694..18815)
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019068256.1"
                     /locus_tag="K1J60_RS41815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K1J60_41815"
                     /product="sensor histidine kinase"
                     /protein_id="WP_259408154.1"
                     /transl_table=11
                     /translation="MRAPSRAPRVWMTDAVLVAVSLTDVWIHDVGPHHPQEPAAALLAA
                     CALVMRRGLPLPTFLLTLPTALFTDAVFATLVALYTLASRTHHRVPLAVCALGFTVCDL
                     TWWSWPSPEFTDLDDRQALIPLSYSVAQATAPLFLGQLVHARRELSLRLVEVSEAREHE
                     RLLIAQSVLAKERAQLAREMHDAVSHQVSLIAVRAGALQVGSRDTEAKEAAATIRLLSV
                     QTLDELRHMVGVLRASGSRPTELTPQPSLADLDRLVAGSGIDTDLRTDLPADLPPPVQR
                     AVYRTVQEALTNIRKHAPGATATIRVRRRDGTLRATVTNTAPSRPALSLPGAHHGLIGL
                     RQRAELLGGTVTSGHLRDGGYELRLELPVDGAP"
     gene            complement(18812..19489)
                     /locus_tag="K1J60_RS41820"
                     /old_locus_tag="K1J60_41820"
     CDS             complement(18812..19489)
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005474551.1"
                     /locus_tag="K1J60_RS41820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K1J60_41820"
                     /product="response regulator transcription factor"
                     /protein_id="WP_220650776.1"
                     /transl_table=11
                     /translation="MIRVLVVDDEALIRTGFEHILNSADDIDVVAAVPGGRAVHTVREL
                     RPEVVLLDIRMPDVDGLTVLAELRRLARPPVVAMLTTFDMDEYVAAALRSGAAGFLLKD
                     TDPEQLPYLVRTLAAGGVVLSSRVTRTVVDGYLDNGPREAAVRLVDRLTERERDVLVLI
                     TEGLSNTDIGDRMHLSTGTVKDHVSALLTKLEVGSRVQAALLAERAGLLRRPRSAGGGR
                     EAG"
ORIGIN
        1 ctcagggtga gccaacgtgc cccgcgcccc ggtcgcatgc ggacgacacc cgggcaggtg
       61 acggataccg ccgtgcgggg gacaccgtgg tctcacccgg cggtggtgac cgtccgctcc
      121 gccgagaacc cgccccaggt cccgtccggc agcttcgccc ggatccgcac gcggtaggtc
      181 accccggcct ccaggcccac gtggaagcgg tacgtggctc gtccccgggg cggggtcccg
      241 ccccagacga gggtggtggc gggccgtccg tcgagctgga tctcgtactc cgtgaccacc
      301 ccgtcgacgg gcggaggcag ccaggacagc tcgacggagt acgcccgctc gtcccggcgt
      361 gtcgccgcac ggagtccggt gggcgcggtg ccccgcccgt cgtccgctcc cggagcggtg
      421 gtgagccgtg ccgtcgcgct cacgggcgag acgttgtccg ccgcgtcccg tgcccgcacg
      481 gtgaaggagt agcgggtgcc cggccgcaac cccgtgacca cggccgccgt ctgctccccg
      541 cccacaccgt ggaccttcga gccgccttgc aggatgtcgt acgacaccac gtcccggtcg
      601 tccgtcgacg gcccccagga caactgcacg gtcctgctgc cgagcacctt cccgtcgggc
      661 cgccccggcc ggctcggggc ccgccggtcg gccgtcccgg cggccggtgt cgtggcccgg
      721 acctccgcgc tcggcggccc gaggtccccg gaggcgccgc gggcccgcac ggtgaacacg
      781 tacgtggtgg agggccggag ccgggtgatg tccaccatgt gctcgtcgcc cggcacgtcc
      841 ttcaccttgg cgcggccccg gtagacctcg tacccggcga tctcggtgtc cccaggtgcc
      901 cggttccaca tgacgtgcac gctggtggcg ctgcccgcgt cggcggtgac gcctggtggg
      961 gcgggcggcg ggagactgcc ggggcgctcc cgcaccgcgc agccggccgt gaggagcagc
     1021 gggccacaga gcgtcggcac caggacgagt gccggcacgg aaacgcgtcg cacgatcctg
     1081 ccccctcgat cgtcgagcca tgacgggatt ggtctgtacc tatctccatg tatgcatgac
     1141 tgacgcggtc acatcaaggg gtgggtccgg atggccgcgg tgcgcggcgg ggcggggcgc
     1201 tacgtatgct ggttctccga cacgacgtga actctcctcc gtgccaggtc ggttcacgcc
     1261 gtacggcgcg ggccgctgtc gtcgccgatc ccgcgccgac gagagcggcc gagcggccgg
     1321 gccgagtcgg gcccggccct cggccgcgca cccgcggaca gcgtgacgca agcgccgtgg
     1381 tccgtccggc cccctcccgg tggccgtcct ctccgacccg caccaccttt gggtgagtgt
     1441 ccgtcatgtc cccccaggag agggtccctc atcgtgcgtg tccgctcgtt gacgctggcc
     1501 gccgtcggcg ccgccctgct ggcccccgtc gccctgcccg ccctggccca tccgcagcgt
     1561 cccgtgcagt acgagggcgg tgtgaccgcc gccgacctgc tggccagggc gcgtgggtgc
     1621 gtccgggtct ccgaggggct gtacagcagc gacgcgggga agcccgccga gatccccgtc
     1681 tgcggtgtcg acggcgcggt gtactggaag gccgacatgg acatcgactg cgacggccgg
     1741 ccgagtccgc gctgcaaccg cgagaccgac ccgtggttcc agcccgccac gtccttcctg
     1801 cagtccgacg gacgctacct ccgctccgag agcctgccgt tcgtcgtcgt tcccgcgccg
     1861 agccgcgtct gggactaccg ggtccacggc atcaagggcg gttcggtcgc cgccgtcgtc
     1921 cacggggacc gggtcgagta cgccgtcgtg ggcgacaccg gcccgcagaa catcatcggc
     1981 gaggcctcct acgccacggc cgaggcgctc ggcatccgcc ccgacccgcg caccggcggc
     2041 accgcctccg gagtcaccta catcgtcttc gaggacaccg aggtgacccc gatcgaggac
     2101 caccaagcgg cggtcgagct gggcggcaaa ctggcccgga agtgggtgga gggggcggtg
     2161 atgcgccgag gcgcgacgat gcggggcggg gcgacgaact gacgtcaccg accgggggcg
     2221 agggagcggg ggaaacgctc cccgtcgccc cggcgcggcc gaccgaccac acccgggtcc
     2281 ctagccgtcc cctagccgag cgacagccgg tcatcttccg tgcgagccgg tcacttctgt
     2341 gcgagcagcc ggtcactcct tccggggccc gccgcctgat ggggcggcgg gccccggaag
     2401 gagtgtgccg ggcgtcggct ggcgccggga ggaggcgtct cccgggttgc ggtcgagtgg
     2461 agggtcactc cttccgatac gtgtacgcct ccgaagccgc ggccgccacc gccgtgaggt
     2521 ccgcgcccgt cgaggccgtg acgaccgccg cgacggcgcc ctccacgaac ggggcgtcca
     2581 ccagacgcgt gtccgccggg agttcgtcgc cctcggcgag gagcgccttc acggtgagga
     2641 ccgcgctgcc gaggtcggtc aggaccgcga ccccggcgcc ccggtcgacg gaggcggccg
     2701 ccgccgagat cagttcggcg ctggtgccca ggcccccgtc ctcggtgcca ccggccgggg
     2761 cgacgggaac gaaggcgccc gcaccggcga gcccccgcgc cagctcggcc accgaggcgg
     2821 cgacagcggc gctgtgcgac accaacacga tgccgacccg cttctcctca gacatcggcg
     2881 gcctccgtgt cggcggtggt ggcgagagcc gcgatcagca gcgcggcgga ggtggcaccg
     2941 ggatcctggt ggccgatgct ccgttcgccg agatagctgg cccggccctt gcgggcctgc
     3001 aacggtgtgg tcgccgaggc gccctcctcg gccgcggccc gcgcggcggc gaacgactct
     3061 gccagcgcgt cgaccgccgg gaccagcgcg tcgaccatgg tcttgtcccc gggtgccgcc
     3121 ccgcccagcg tcatgaccgc gtcgaccccg gcgcgcagcg cgtccgtgag ctgggcctcg
     3181 ctcacctcgg cggcgtcgcc gagcgccttg ccggtccggc gcagcagggt gccgtacagc
     3241 gggccggacg cgccgccgac ggtcgagatc agctgtcgtc cggcgagcac caggacggcg
     3301 ccgggtgtgt ccggagcctc cttctccagg accgccgcca cggcggtgaa cccgcggtgc
     3361 agattgctgc cgtggtcggc gtccccgatc ggcgagtcga gctccgtgag ccgctcggcc
     3421 tcgcgctcca ccgaggccgc ggttgccgtc atccagcgac ggaagaaatc ggcgtcgagc
     3481 acggaatctc cttgcgtggt cagtgagttg acgggtggtg aggggtgctg ccgccgagcc
     3541 ccgccatgcg cggccgtccc ttgcggaccg ctcacacgcc ccagcgcaga cccggcgtcc
     3601 gcaccggagc gtcgtacagc cgcagcagtt cctcgtcgac ctggcacagc gtcaccgacg
     3661 cgccggccat gtcgagcgag gtgacgtagt tgccgacgag cgtgcgggcc acggcgaccc
     3721 cgcgctcggt gagtgcccgc tgcacctccg cgttgaagcc gtacagctcc agcaggggcg
     3781 tggcgcccat gccgttgacg agcagtagca ccgggttgcg ggggctcatg tcgtccagga
     3841 cggcgttcac cgcgaagtcg gcgatctccc gcgaggtcat catggcgcgc cgctcacgac
     3901 cgggctcacc gtggatgccg acgcccaact ccagctcccc ggcggggaga tcgaaggtgg
     3961 ggctgccctt ggccggggtg gtgcaggcgc tcagggccac gccgaagctg cgggagctct
     4021 cgttgacctg ccgggccagc gcctcgacct gctccaacgg ctgcccctcc tcggcggcgg
     4081 cccccgcgat cttctccacg aacaaggtcg cgcccgtgcc gcgccgcccg gcggtgtaga
     4141 ggctgtcggt gacggcgacg tcgtcgtcga cgaggacctt ggcgatccgg atgccctcgt
     4201 ccgcggcgag ctcggcggcc atgtcgaagt tcagcacgtc accggtgtag ttcttcacga
     4261 tgaacagcac cccggcgccg ctgtccacgg ctgccgcggc ccgcaccatc tggtccggca
     4321 cgggggacgt gaacacctcc ccgggacagg ccgccgacag catcccgggt cccacgaacc
     4381 caccgtgcag cggctcgtgc cccgaaccgc ccccggagac cagccccacc ttcccggcca
     4441 ccggcgcgtc ccgccgtacc accacccggt tctccacgtc cacggtcaac tcgggatgcg
     4501 cggccgccat accccgcaac gcgtccgcga cgacactctc ggctacgttg atcagcattt
     4561 tcatgtgtgc ctcccggtga ggttggtcgg tgtgctcatg acctgcgtgt ggccgggtcg
     4621 gagctttctc catggtccgt cagatctctt tggtcgtgtc gagcgtcaag cgacgagtgc
     4681 gagtgcgagt gcgagtgcga gtgatgagtg acgagcctcg tcgtcggagc agggtgtgtg
     4741 cgcacagcag gttgccttcc gtgacggtcg gtggcgaacc gagcgtagtg ctgggccagt
     4801 tgagtgcgat accgggcgcg ggtcgacaga tccggcagcc cgggggagcc caccaggcgc
     4861 cggtggtacc gcagtggctt ctcgtgcccg cttccgcccg cacttcgcat acacctgctc
     4921 gtcgtggatc aaccaggtcg aacgtccggc tcgccgagcc ggaaggacac cgcctccgac
     4981 gcggagtggt ccgctccgcg cgggcgacct gccccgtcct tcgagtcggc cgccgcaggc
     5041 cccggtccac ccggctcgct cgccacgccg tcgacaacat cctccatcca ggggcccggg
     5101 cctgccatcg caccggaacc ggcgcggcgc atgcgacttc gagggcggaa gacgaccggg
     5161 cgctgccggg agccgggccc accgccgtgc ggggctcgta cccccgggtg gcgggggtgg
     5221 gccgggcctt cgtcggatcc tccggcccgg gtcggcccac agcctggacg catgccccgg
     5281 aacgcagacg acacggtggt cgtcccaccg ggtacctcgt cggccgaagc cccggtgggc
     5341 gagccgagca cccgcgcccg ggaccagacg ttcccaggca gggcgcctga tcggcgtgga
     5401 gctggcgcgg gggctcgcgg tcttcgggat gtacgcggca cacctcggtc ccgacccctc
     5461 cgaaggcggc accaccggct tcctcgtgga acagttcagc gcccgcccgg tcggcatcat
     5521 cggcgccgcc gccaccgcgc ccaacggcga cctgcaccag gccaccctca ccccctgatc
     5581 ccaccccgac cccgataccg gcttctcggc caccgcggca acagacgggc atggcgacga
     5641 ggtgatcacc ccccaccgcc gcatcgaaca ccctggatgc cggcgcccgt gtcaccgctc
     5701 tcggcgcgtt tctgccgggc cgctcggacg agagccccgc gggtcgacgg cggtcgcggt
     5761 cctgatgtat tcaccattcg cccgggacgc ccactcgctg agcgccgtca ccccgtcaga
     5821 aagtcgacga gagccgcgtt cacctcgtcc gggcgctcct gctgcgtcca gtgtccacag
     5881 ccgggcaact cgacgggctc gccccgaagg ctgggcatca ggtccggcag ggccgcgatg
     5941 agttcgggcg tgccggggaa cgcgggcacc agatcacggt cgccgtagac gaacagggcg
     6001 ggcggggtga cgcgggcgtg gtgccagggt gccgtcagct cccagttgcg gtcgaggttg
     6061 cggtaccagt tgagtgctcc ggtgaagccc cgggagaaac tctcggtgag gacgtcgagg
     6121 tcgtcctcgg tgaaccactc cggcagcgcc tcggggtccg cgagcgtcgt gagccagccc
     6181 cgctcgggat cgaccagggg ctgcctgtcc tcgccggtga cgcgagcgtc gccggaggcc
     6241 cagtagaaga tcttccgcag cgtggtgcgg gggtcctcgg cgaactcggc gtcggcgaca
     6301 cccgggcggt tgaagtagtt ccagtagaag cggccgccgt acctctcctg tgccgccacc
     6361 agcggaggct gcttcccccg gaaggggggc ggcacgctca ggccggccac cccgagcacc
     6421 atgtccggcc gcagcagtgc ggtgtgccag gcgaccggcg cgccccagtc gtgtcccacg
     6481 acgtacgcct tctcctcgcc gagcgcccgg atcagcgcga cgacgtcgcc gaccagatgg
     6541 agaatggtgt acgcctcgac ggcctcgggg cggtcgctgt ctccgtagcc gcgctggtcg
     6601 ggggcgacga cgcggaagcc cgccgcggcc agcgggtcga actggtggcg ccaggagtac
     6661 caggactcgg gaaagccgtg cagaagcacc acgagggggc cggcgccctg ctcggcgatg
     6721 tgcagtcgta ctccgttcgc ttcgatcatt cgatgcgcaa ccatgcgaac gagcgtacgc
     6781 gtcgggggat ccgggtcccg gtggagcctg gccgccctcc tggtgtggtt gtcagggctt
     6841 gacgtaggag cagatggcca agggcgagtc cgggccgtac ggggccgcgt cggccggcca
     6901 gtcgccccag cggcgttcgg gttcgaggcc ggcggcgcgg gcgtaggcgt cgaattcctc
     6961 cggcgcggtc aaacgggaga cctcggtgcc cacccgggtg gtgccgtcgg actcgtacca
     7021 gacgtgggag aggtgccaga gggacccctc ggggaagagc agggagtggc tctgcagacc
     7081 ggtgccgggt tcggggtagg gcgtgaagta cgtggcgcgg gcgcggcctt cgtgcagggc
     7141 gaggacggcc ggcttgttgt gggtctccac gaccagtcgg ccgccggggg cgagcaggtc
     7201 ggcggcgcgc cgcaccgcct gctgctgctc ctcgggggtc agcagcatgg agagggtggc
     7261 gcagatcgcg tacaccagcc ccacggtgcc gtcggcggtg taggtgcgga tgtcggcgtg
     7321 cacgggctcc acgggggttt cctcggtgag gtcccggcgc agcagggcga gcatctccgg
     7381 ggaggagtcg acgccggtga tcctgccgac ccggcgggag agcgggaggg cgatgcgccc
     7441 gttgccgaca ccgaactcga ccgtccccgt ggccgggtcg gggtggagcg aggcgaggag
     7501 atccacctcg gcgacgacgg acgcgtcgtc ggggaagagc cggtggtacc agccgtcgaa
     7561 ctgccgtccg tagccgatgt cgtcgacgat gccggtcgtc gtggtccggg ttgctgtccc
     7621 ggtccgggtg gtcgcgccgg ccgtgggggt cttggtcagg gtgacggacg tggtggacgt
     7681 ggtggacgtg ctcatgggtg gtgcctccgc ttcttgggtg gggtggtcct cggatgggcg
     7741 ttccttctgg cctgggagca ggccccgagc agcaccacga gggcgacgcc gaggacggcg
     7801 ggggtgctga cggcccgggt ggtgatgagg aagccgacga tgccgagggc caccacgaac
     7861 gggatcagca ggaagtcgtt catcaggttc tcctttgggg gaggtcgttt cgggaacttc
     7921 gttctcctgt cgggtcttcg gtcaggacgc cacgtcgctc agcgcctgga gccgggcgag
     7981 ccggcggtag aggtcgctgt ggcggtggag ttcgtcgtgg gtgccgacgg cgtgcacccg
     8041 gccccggtcc agcacgacga tctgctgggc ctcggtgacg gtggacagcc ggtgggcgat
     8101 ggcgatgacg gcgcagaagc cggagatcat ggcgatgctg tcgcgcagcg cgttctccga
     8161 ctcggtgtcg aggttcgcgg tggcctcgtc cagcagcagg aaccggggcg cctgcagcaa
     8221 cgtccgggcg atggccaggc gttgtcgctg acctcccgac aaccccgcgc cccgatcgcc
     8281 cagttcggtg tcgaggccgt gcggaagcgc ggcgatcacc tcggtcaggt tggccatgcg
     8341 cagcgcctcg gcgatgtcct tgtcgtccgc gtccggcgcg ctgtaggtga ggttctcgcg
     8401 gacggtgccg cgcagcagcg tgtggtcctg gtcgacatag ccgacgatgg accgcagctg
     8461 gttgagcggc agatcggtga tgtccgtccc gtcgatgcgg atcgccccgg acaccgggtc
     8521 gaagagccgc tcgatcagct ggaagagggt ggacttgccg ccgccggagg gaccgacgat
     8581 ggcggtcagc cctccgggcg ggacgctgaa ggagaccccg tcgaggacca tcttgtcgct
     8641 gcccgggtag gagaaccgga caccgtcgaa gcggagtccg ggctcgtagt cgcgcctgag
     8701 cgggcggaca ccgcgcggcc gttcggccga cggtccgccg accgcgtccg tctcgacctc
     8761 gatcctgccg agctccgcga gccggtccac cgacgccctg ccgatctgga actgcgcgat
     8821 cgactcgaac agcgtcagca acggcgccac caggtagaac aggtagagga tgaacgccgt
     8881 cagatcggcg gtgggcatcg ccccggtcgc cgtgcgggcc gcgcccagac cgatgacgac
     8941 cgtcagggcg agctgggtgc cgatgctcat ggtcgggtcg agcagcgacg acatcaccgt
     9001 caccttgatc cccgacttcc gggctcgccg ggcgatggcc gcgatcccct cggcctcccg
     9061 gctctcggcg cgggaggcct ttacggtggg catcgccccc agcacccgca gcagggcgga
     9121 gccgaaggtg cccaggtcgg cctggttgag caccgacacc ctccgcaccc cgcgtgccag
     9181 ccagagcgag acggcgctcg tcacgccgag gcaggccagg gtcgcggcga gcagcacggt
     9241 gtcgatccag gccatcaggg cgatcccgcc gatgaccagg aaactgttgt tgaggatgct
     9301 gtcgatggcg tgggtcatgg tggagcgggc gagcatggtg tcgctgacca tccgggagaa
     9361 cacatcgccc tgctgcagtc cgctgtacgc cttgaaccgg gagcgcagca gccgcgaggc
     9421 gagcgtccgg cggatgtcgt agacgatgtt ctcgccggcc agcccgatga cgtacgagtg
     9481 cagtgcgccc agagcggcgt cggcgatgaa cagcgccgcg cccaccagga tcgggccggt
     9541 caccgagcgt ccctcgccga cggcgccgac gagttggccg atgaccgcgg gctgggccag
     9601 ggaggtcccg gctcccacca ggccgaggaa gatcccgagc aggaccagcc ggcggtgacg
     9661 gcccatggcc cgccagggtt tggctccctc gccccacagc aggtgcagat tgagctgggg
     9721 gaccgcccgg tgcccggccc gccgcccgcc accgggcccg ccctccttcg ccaggttcac
     9781 cggggggtcc tgcgggcggg tgtgccgccc ccggccggcc ggaaggtcac tcatcccggg
     9841 ccctcggccc catggcggcc gtccgtaccc ggctcactcg tgttccctcc cttcctcttt
     9901 cgcttccgcc tgggacctgc ggatccgcag gcccgccttg agcagtccga gcgcgaatat
     9961 cagcatcgcg agcaggatga aggggatggc gaagtccatg tcacaccttt gcgggagtct
    10021 tggccggggc cgacgtcagc ggggtgcccg gggcctgcgg gtcgagggga acgaacgggg
    10081 agacgaacat cagctcggga cggtggcgcg tgtcgaagcc ggtggcccgc gccagcgcga
    10141 actggaagcc ccgtacttcg tcggccgcga ggccctggga cctgatgagg agacgcaggt
    10201 gctcggtgac catccggtag ccggggaccc gggaagcggc ctcgaagccg ccgaactcga
    10261 gggtcgggag gatgtcggcg cacgcgtcgg agacgccctt gtccgcgcgc cgggtgggga
    10321 accacacgat gtgctggggc ttgcgcgtct cggtcgtgaa cccgtcccgc cagggcgagg
    10381 cgttgccctc cgcgtccacc gtgcggtaca ggaagtggct gtcgtgcata caggggttgg
    10441 gggcgaagaa ccgccagttc ggtaccaggg acagaacgtc cttcgtacgg aaccgggaga
    10501 actgttcgaa ggggtgctgg cccgcgaagg tgacgaccag catggcggcg ccggcgatcc
    10561 gccaggccgc gccctcgccg gtgaacgggt tcttcagcgg aagacgtcgc ggcatgctca
    10621 ccgggaggcc tccttcctga gggtgacgga tcgggtggac cgtgccgcgc gggggcgctc
    10681 gtcgaggttg tggaagaagg cgaggacacg gtccgtcacc tggtgggcgt agcggctgtt
    10741 gatcagcagg gtgtcgtgcc ccgccccctc gatgaccacc gtctcggtgg gcgccccccg
    10801 gtgggcctcg gccagttccc ggtgcatcag cagttgttcg gggtcgcggt ccacggtccg
    10861 ctgggccgag atcaccaggc agggcacgcc ctcgatcgga gcgagtcgac cggggaaggc
    10921 ctcgaagtcc tcccgcagcg ccgtccattc acggcgtgcc gcttcccaca tccgcgcgtc
    10981 ggagtactgg gcgaagacct tgtcctggta ggcggcgggg agttccttga tccaccacgg
    11041 gcgggtgagg agggccccgg tgcccagccg cagggctcgg ctcatggagg tgaaggtgct
    11101 gcccaggccg gcaccggtca cccgctgctg ggcggaccgg tggaactggt cggggtgcga
    11161 ggagtcgagg tacacgacgc cgtgcacccg gtcgccgagg tgcgtcaccg cacggcgggc
    11221 cagctcgccg ccgatcgagt ggccgaccag gaccaccttg cggtgcggtg ccacggcccc
    11281 gttgaccagg tcgacgaggt cgtcgacgga ctccgtcagc cggtaggcgg tggtcgccct
    11341 gcggtggctc ccggcgtacc cggcgcgggc gtaggtgatg acgccgtacg aggtctcgta
    11401 ggccaggcgc tcgctgatcc aggcgtagtg ctcgctggtg gacagcagac cggcggcgag
    11461 cacgaagacc ggccggtcgg cgtccccggc ggccatctcc tcgtactgga gccggttgcc
    11521 gtggcgggtc gtcagcactc gggaggtccg ccagccctcg gtggcgcgca tgcgccggtg
    11581 cacggcggtg acgcccgcgg ccgccgtcgc acccgcgagc agggtgaggg cggcgggcag
    11641 ggcgcggtcg tcgcgtcccg ccaccgcggg gtgcgtgcgg ggggccgcgg tgtaggcgat
    11701 cagcgggtgc atcgcgggga acgcggtggc gaacctgccg agccccatga agtagccgtt
    11761 ggcgaggtgg aacgcggcgg cgctcgcgag gacgggacgg gtcagtcggc cgcccttgag
    11821 ataggcgagc gggaagaggc attccagcgc cagcacactg tgggcgagca gcttggcggc
    11881 ccgggggttg ttccggatcc aggtgtgcat gccctcgtgg ccgtaggtgt gcgtgcgcat
    11941 cacacccgga agggccgaac cgtcgcgcca gtccgggccg agcagcttga cccagccgga
    12001 gaccaggtag gagaggttgg actgcagggc gacgtaccac atcagggcgt ccttggcggc
    12061 cggcgagggc accagacggg cgccgccggt ggcgagctgt acgagggtcg ccacctggtc
    12121 ggcgccgtcg ctgccgtagt gctggcgggg gccgaggagg gcggaggtcg caccgaggaa
    12181 gaggctgccg gcgccgcgcc agggggacct gcccggcagc agcatggcgg aggcgaccgc
    12241 ggcccgtgtg acgtgcagag ccgtcgtggt ccgccgtccg ctggcgatgt cgatcactcg
    12301 acgcagcagg gggttcgcgt gcgcgacgct gtccttggcg atgtcccagt cgttcatgcc
    12361 tcccttgtcc atctcatggc gctggctgag gtattcgagg gacgaggtga ggctcgtcgc
    12421 ggcggccagc cgctccgaca ggcccagcgc gcggtcccgg ccgaccggta tcgggccgag
    12481 caccgcggag gcgaccttgt ccgggaccgc agaggtgatc cttcggacga gtttcatgga
    12541 acctcttttc ctggtacttt cgaatgcgtt ttttgagtac ggcggaaccc gctgccggac
    12601 cagaacagcc ctctggtccg acagcgggtt cctatgcgat caccgtcggt cgtcagaccg
    12661 cgggcggcgt accgccgacg gcggcgagcg cggcctggtt ctgggcgttg gcctccgccg
    12721 ccaggttgtt ggcctccgcg gcctgcgcga caccgaccgc cgcggtggcg gccgccgcga
    12781 gggcgccgac accctcggcc gcctgggcga tgcggccgat gcgggcgatc cgcggggtgc
    12841 ccagggtcgg gcgagcggcg acgtagacga caccctcgac ggggatttcc acgctgttca
    12901 gcgcgttctc gatgctgctc atttctttca tcctctcgca ttcgggactg cggaagttct
    12961 tttcttccgg tgcccttctg gagaaaacat tagggcctct ccggccgtct ccacatcgat
    13021 aaaaatgcct attgttgaaa gccgtccttc gcgccggggc atcaccccgt ggacgcggaa
    13081 aaggcccgga ccgattcggt ccaggccttt ctcaggaatg tcgcggccgg cggctgccgg
    13141 gtcattctcg accgtgccgt cgccggagat gacgcagggc ggacgcggcg gcgttcgcgc
    13201 cgcacatgcc gtgggcgccg gctcccggtg gtgacgcggc ggagcagatg tacatccccg
    13261 ggacccccgt gcggtacggg tcgagggcca cccggggccg catcaccagc tggagggcgg
    13321 tgttcgcccc ggtgacgacg tccccgccga cgtagttcgg gttgtagtcc gcgaaagcgg
    13381 cgggcgggcg gacggccatg tcgaggacac gttcacggaa ccccggcgcg aaccgttcga
    13441 tctgcccgat gatcgcctcg gtcgcgtcgc cgtcgtagcc gtgcggaaca tgtgcgtagg
    13501 tccagacggg atggaggtcg cccttcgagc ggctcgggtc ggccaggtac tgctggccga
    13561 ccaggacgaa aggccgttcc ggcatgcgcc cggcctggat catccgctcg gtgtgggcga
    13621 cctcctcgaa cgttccgccg aggtggacgg tgcccgcccg acgggccgcc tcgttggtcc
    13681 aggggacgcc gccctcgacc gcgaagtcgg ccttgaaggc tccgggcccg tggcggaagc
    13741 gccggtaggc ccgcgcgacg cgtcccggca gccggtcgcc caggatgtcg gcgacggcgc
    13801 ggggggcgag gtcgaacagg accacgtcgg ccgggggcag atcggccgag gcgcacacct
    13861 tcactcccgt ctcgatccgg ccgccgaact cgaagagctg tgccgcgagc gcgtcgctga
    13921 tcgcccggga tccccccgcg gccaccggcc agccgtgccg gtgacccgcg gcgacgatgg
    13981 tcagaccgac cgcggcgccg gccggcaggt ggaaggggcg gaaggcgtgc gcggccacac
    14041 cggcgaagag cgcgcgggcg gccggcgacc gccacagccg ggccaccgcg acggtgggca
    14101 gcagggcccg cgacccgaag gccgcgaggc gcagcggatg gcgcggcaca tgcgggagcg
    14161 gcagcatcag atcctcggcc agcgcgtcga agccgtccgc gagcggcccg aagagccgct
    14221 gccagcggcg tccgtccact cctccgaggc cgtccgcggt ctcctgcacc gaccggtgca
    14281 ggacgccggc ctcgccggag tccagggggt gcgcgcagtc gatctccggc aggcaccagg
    14341 tgaggccgtg ccggccgagg tcgaggtcgc gcaggaacgg cgaggcgacg gccatgggat
    14401 gcgttgcgga gcagtggtcg tgcagcagcc cgggggtcag ttcgctggtg cgggtgccgc
    14461 cgccgatggt gtcggcggct tcgaggacgg tgacgtccac gccctcccgg gcgaggaaca
    14521 cggcggccgc gagaccgttc ggaccgctgc ccaccacgac ggccgtagtc ataggtcttc
    14581 cgtgcctcct cgatgacggg cgccgggcct gggcccgcgc gcggcggacg ggagacgacc
    14641 ggttccgaag cggtgtgcgg aaacggggac cgggccctcg aaagagcccg gtccgcgccg
    14701 attcaccact ctgcgggacg tggggaaggc cgtcccggcg ccttttggtt ctcagacgat
    14761 agagggtgga tcggccgggc gcgattcgca gaattgccta attcacgccc ccgatcgact
    14821 aactcgcgtc ccagctcatg tccggctcgg gttccgcgtg cgcattcggc ttcgcatgac
    14881 gcccgggttg ccggcgggat cccggacccg atcccgcggc gtcctcggcg ccggggagca
    14941 cggccggtgg gagtaccggg aaatgggcga tgatccacca gcccccgtcg tcggccgggc
    15001 ccgccgtcag ggagccgccg accgtctcca cgcgctcgcg cagcccgatc aggccgtagc
    15061 cccctctgcc tcccgtggga cgggagaccc gccgctcggg cccctcgttg tacacgtcga
    15121 cccgcagcag gtcgtcgcgg gtgcggtgga cgcgcaccgt ggcctgggtg cccggtgcgt
    15181 gccgccgtac gttggtcagc gcctcctgga ccacgcgatg gacggccgag cccacctcgg
    15241 gcagcagacc gcttctgcgg gcggccccgg tgatctccag ctgggcggtc gaaccgtcgc
    15301 cctggtcgct gaactccgag accagtttcg cgagttcggc gtacggctcc tcgggacgtt
    15361 ccagggagac ctgctcgccg tcctcgcgca gcacccggat cagccggcgc atggagtcca
    15421 tggtccgctg cccggcctcg gcgatgttgc ccaggatggg cccgacctgg tggggcgcgc
    15481 tctcgtggac cacaccggcg gcgtgtgcct gggcgatgat gcccgtcaca tggtgggcga
    15541 cgaagtcgtg cagttcccgg gcgagttgga tccgctcggc gagccgtacg gcggcgatcg
    15601 tgcgacggcg ccgggcgtcc agggtgcgca ggtagcaccc cgcgccgatg gcgccgccga
    15661 ccgcgaacgt cagcaggaac gggtaggtga gggtgatgct cgtgcccccg gtgcgcaggg
    15721 gttcgtcgat gacgctggcc cccatcgccg cggccagcgc gagggcgacc cggggccggg
    15781 ccacgtggcg gcaggtgcgg gcgagcagga ccagcatgca cgccgtctcc agcagccccc
    15841 actcgggcat ggcccagccc atcagggacg tgcccagagt caccgtcgtc gagacggccg
    15901 cgcagaaccc cgtacgccag gtgatgctca gccgcgattc gggcaccagc accagagcca
    15961 gcgcgacggg gcccgtcacc agcggcaacc agtcgagggg gccccgttgc tgcgacacga
    16021 tgatgcccac gtcgagcagc cacagcacgc ccagcgccgg atacagagcg cggtggtcca
    16081 gccgtcgcgc gggtaaccgg gggcggccgt gatggtgcgg ctgggtcgct cgtgccgaga
    16141 gtgccgcgag tgacgaagtt gtcatacaac cggaggctag gcatgcacat gcttccccgg
    16201 cagggagtgg atcgatgtgt gggcagcgtc atagatcgat tacagggcgc tcaccacatc
    16261 cccgtcaccg ccctgtccgt accgtcccgt tggcccaggc ccacgcggcc acctcgacgc
    16321 ggttgcgtac accgagcttg tggtggatgt gacccaggtg cgtcttcacg gtggacagcg
    16381 acagacagag ctcgtcactg atctcctggt tggtccggcc caccgcgacc agccgggcca
    16441 cctccaactc ccgtgcgctg agcgaggatt cgggcacgcc gacaccgtcc accgggaccg
    16501 ccgcccgctc ctccaactgc ttcagcagcc ggaccgtcac cgcgggggag accagcgcgt
    16561 caccgcgtgc ggccgcccgt accgcctcga tcagcagcgc gggcgccgcg tccttcagga
    16621 ggaagccgca cgctccgttg cgcagcgcga cgttgaggta gtcgtcctgg tcgaagctgg
    16681 tgaccaccac gacctgggtc gggtgcgtgg cccccggccc ggcgagcagc cgggtcacct
    16741 ccagcccgtc cagcttcggc atccggacgt ccaccaggca cacatccggc cgcagcgcgc
    16801 gcgccagctc cacgcacgcg agcccgtcgg cggcctctcc gatcacctcg atgccctcct
    16861 gggcgtcgag gatgagacgg aaaccggccc ggatcagatc ctggtcgtcg gcgatcatca
    16921 cacgtgtggg ggtgtggctc acgcggccga gcatgccatg gatcatccgg ccggtccggc
    16981 ggtccgggga agccggcccg ccaagccccc tgccgaatcg ggcagttggt gcttacccgg
    17041 cgaaagctcc gccccggagg gtgggaccga ggccgatcgg ccgatgacta ctgcccggta
    17101 tcggtcgaac ggtcgatggc cggtgcccgg atgtcacgga agagtcacag cgcagcagat
    17161 gaacggcacg cggggtcctc gacccccact tcggacaagg caggcaccca tggcattgga
    17221 cagctccggc cggctcagcg cccgggaaat ggagatcctc cttctggcgg cccacggcat
    17281 gtcggacgcg gacatgtctc gtcagctgtc gatctcggtt cgcacagtgg cttcccatat
    17341 gcgcagcatc cgggagaagt tgtgcgcgaa gaaccgtaca cacctcgtgg tgaccgcact
    17401 gcgcgcggga atcctcgcgc tgcggacgga ccggatggac cgcctcgacg aaacgttccg
    17461 cttgaccggg cgcagcgggg tccggccgcc gcgacccgtc ggcatcgcgt agcgggtgag
    17521 cgtgtgcccc gggccggttg gtgcggcccg gggcacctgc gcgtcagccg ccggtcctcg
    17581 gcagcaagga gatgatcctg ccgcggggcg atggccgacg cggtggacgc ggagagcctc
    17641 tcccgggact gcgtccccgg cccggcctcg acccggggcc gggccgctac cgctcacggc
    17701 gcgccgtcga ccggcagctc cagacgcagc tcgtagccgc cgtcccgcag atgcccggag
    17761 gtgaccgtcc cgccgaggag ttcggcgcgc tggcgcagac cgatcaggcc gtggtgggca
    17821 cccggcagcg agagggccgg gcggctgggc gcggtgttgg tgacggtcgc gcgcagcgtg
    17881 ccgtcccgcc ggcgcacccg gatggtggcg gtggcaccgg gagcgtgctt gcggatgttg
    17941 gtgagggctt cctggacggt gcggtagacg gcgcgctgga cgggcggcgg caggtcggcc
    18001 ggcaggtccg tccgcaggtc ggtgtcgatg ccgctgccgg cgaccagccg gtcgaggtcg
    18061 gcgagggagg gctgcggggt cagttcggtg gggcggctgc cggaggcccg cagtaccccg
    18121 accatgtgcc gcagctcgtc cagggtctgc acgctcagca gccgtatcgt cgccgccgcc
    18181 tccttcgcct ccgtgtcccg gctgccgacc tggagggctc ccgcgcgcac ggcgatcaga
    18241 ctgacctggt gggagacggc gtcgtgcatc tcccgggcga gctgggcgcg ttccttcgcc
    18301 aggacgctct gcgcgatcag cagccgctcg tgctcgcgcg cctcggagac ctcgacgaga
    18361 cggagcgaca gctcccgtcg cgcatggacg agctgcccga ggaagagggg agcggtcgcc
    18421 tgcgccacgc tgtaggagag cgggatcagg gcctgacggt cgtcgaggtc ggtgaactcc
    18481 ggtgacggcc acgaccacca cgtcaggtcg cagaccgtga accccagcgc gcacacggcc
    18541 agcggcaccc ggtggtgggt gcgggaggcg agggtgtaca gcgccaccag cgtggcgaac
    18601 accgcgtccg tgaacagggc ggtcggcagg gtgagcagaa aggtcggcag cggcagcccg
    18661 cggcgcatga cgagcgcgca ggccgcgagc agggcggcgg ccggctcctg gggatgatgg
    18721 gggcccacgt cgtggatcca cacgtccgtc agggagaccg cgacgagcac ggcgtccgtc
    18781 atccacacgc gtggggcgcg ggagggggcc ctcatccggc ctcccgtccg ccgccggcgg
    18841 agcgcggccg cctgagcaga ccggcacgct cggccagcag cgccgcctgc acccggctgc
    18901 ccacctccaa cttggtgagg agcgcgctca catggtcctt gaccgtgccg gtgctcaggt
    18961 gcatccggtc accgatgtcg gtgttggaca gcccctccgt gatgaggacc aggacgtccc
    19021 gctcacgttc ggtcagccgg tccacgagcc ggacggcggc ctcccggggc ccgttgtcca
    19081 ggtacccgtc gaccacggtc cgggtcaccc gggacgacag gacgaccccg ccggccgcca
    19141 atgtccgtac gagatagggc agttgctccg ggtccgtgtc cttgaggagg aagcccgcgg
    19201 ctcccgagcg gagagcggcc gccacgtact cgtccatgtc gaaggtggtg agcatggcca
    19261 ccaccggcgg gcgggccagt ctcctcagtt cggcgaggac cgtgagcccg tccacatcgg
    19321 gcatacggat gtccagcagg acgacctcgg ggcgcagctc ccgtacggtg tggacggccc
    19381 ggccaccggg gaccgccgcg accacgtcga tgtcgtccgc ggagttgagg atgtgctcga
    19441 agcccgtacg gatcagggct tcgtcgtcga ccaccagtac ccggatcacc cgtgccccgc
    19501 tcgtcgtcgg accaccactg gacttctgct ggaaccgcta cgacgtccga agtcgccgcc
    19561 tggttcccat tcctccccat ttccggtcac ctggcggggg tggctccggc tggtcggcgg
    19621 gagaacgtcc agccacccgc cggatggaga cgcgcccctc gcgcccccga cgctgaaggc
    19681 catgactcca gacacgtcgt cggacctgtc gtccaagccg gtcgccgcac cctttcccgc
    19741 ctccgcctcc gcctccgcct ccgcctccgc ctctgcctct gcctctgcct ctgcccctgt
    19801 ccccgcctcg ccccccacag ccgtcggagt ctccgcgagg ccgtccaccg ggcggctggt
    19861 cggcatcgat ctggcccgtg gactcgcggt cttcggtatg tatgccgcgc acgtcggccc
    19921 ggacccggcc gacggcgggc cgctgggctt cgtgatggaa ctggcacggg gccgctcctc
    19981 cgcgctgttc gcgctgctcg ccggtttcac cctcgtcctg atcaccgggc gcccgcaccc
    20041 gcgcaccggg cgcgccggac gccaggcggt cgtccggatg gtcatccgtt ccctcgtcct
    20101 gatcgtcctc gggttcgccc tgacctccct cgacaccgac gtcgacgtga tcctcgcctt
    20161 ctacgggctg accttcctgg ccgtcctccc cctccaccgc ctgcgtgccc ggacgctcgc
    20221 gctcctcgcc gccgtgggcg cgctcgtcat gccccaactc ctccacgtga cacggctgtc
    20281 gatcgaggag ggcgactggg cggacgcgat cgtcgccgcc gatccgctgg cccggatcag
    20341 cgacaccgac ggcttcatgg agctgctgtt cacgggcgag tacccggtgc tcacctggat
    20401 gtcgttcatg ctggccggga tggcggtggc ccgactcgac ctcaccagga acaccgtccg
    20461 cgcccgactg gcgtgcacgg gcggcgcgtc ggccctgctc ggctacggcg gttcctggct
    20521 ggcactgcga ctcgtccccc acgcgcgggc caccgtcgcc gccgccacgg acggcgactc
    20581 ggccgcgtcc gcctggtggt ccgacaccgt cggct
//
