LOCUS       NZ_SISU01000003        22290 bp    DNA     linear   CON 09-SEP-2024
DEFINITION  Clavibacter michiganensis subsp. michiganensis strain 0317
            NODE_3_length_469008_cov_98.2229, whole genome shotgun sequence.
ACCESSION   NZ_SISU01000003
VERSION     NZ_SISU01000003.1
KEYWORDS    WGS; RefSeq.
SOURCE      Clavibacter michiganensis subsp. michiganensis
  ORGANISM  Clavibacter michiganensis subsp. michiganensis
            Bacteria; Actinomycetota; Actinomycetes; Micrococcales;
            Microbacteriaceae; Clavibacter.
REFERENCE   1  (bases 1 to 469008)
  AUTHORS   Peritore-Galve,F.C., Botero Rozo,D.O. and Smart,C.D.
  TITLE     Characterizing tolerance of wild tomato species to the bacterial
            canker pathogen
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 469008)
  AUTHORS   Peritore-Galve,F.C., Botero Rozo,D.O. and Smart,C.D.
  TITLE     Direct Submission
  JOURNAL   Submitted (13-FEB-2019) Plant Pathology, Cornell University, 630 W.
            North Street, Geneva, NY 14456, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: JAN-2019
            Assembly Method                   :: SPAdes v. 3.9
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 90.0x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_019455805.1-RS_2024_09_09
            Annotation Date                   :: 09/09/2024 05:23:58
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,211
            CDSs (total)                      :: 3,157
            Genes (coding)                    :: 3,134
            CDSs (with protein)               :: 3,134
            Genes (RNA)                       :: 54
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 47
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 23
            CDSs (without protein)            :: 23
            Pseudo Genes (ambiguous residues) :: 0 of 23
            Pseudo Genes (frameshifted)       :: 4 of 23
            Pseudo Genes (incomplete)         :: 18 of 23
            Pseudo Genes (internal stop)      :: 3 of 23
            Pseudo Genes (multiple problems)  :: 2 of 23
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 02:12:03
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 221906
            Orig. end                         :: 244196
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            SISU01000003.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22290
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="azole-containing-RiPP"
                     /region_number="2"
                     /rules="((YcaO or TIGR03604) and (((thio_amide and (PF06968
                     or PF04055 or PF07366)) or Lant_dehydr_C or Lant_dehydr_N
                     or (PF06968 or PF04055 or PF07366)) or (goadsporin_like or
                     PF00881 or TIGR03605)) or TIGR03882 or TIGR03603 or
                     thiostrepton or TIGR03602)"
                     /tool="antismash"
     cand_cluster    1..22290
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="((YcaO or TIGR03604) and (((thio_amide
                     and (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /kind="single"
                     /product="azole-containing-RiPP"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22290
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12290](+)"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12290
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="1"
     misc_feature    1158..1176
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 20.15"
                     /tool="antismash"
     gene            1258..2607
                     /locus_tag="EOG37_RS11200"
                     /old_locus_tag="EOG37_11185"
     CDS             1258..2607
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /function="ABC-type sugar transport system periplasmic
                     component"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1143: sugar-binding lipoprotein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012039472.1"
                     /locus_tag="EOG37_RS11200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EOG37_11185"
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="WP_012039472.1"
                     /transl_table=11
                     /translation="MSTMRRAGRAAALTAAAAISALALASCAPGSAPVASAPAGDVSTA
                     IPTDDVTIRIQDETGFPVTDELTAEFTKQHPNVKFDITRDSFQNLLANTPRLLASDDAP
                     DLIRLSTLGTTVKDGLLTNLDPYFDAYGWDRFPAGQLAGARMDDQGVRGEGSLWQFGIG
                     YSVTGIYMNQELADQVGITEMPATMDELEADLAKAKDAGVLPIQTGMQDGVGTFILQSL
                     INQQGDKQDLVDWMYNKPGATIQTDAALAGATKFQDWAKAGYLPPDVNAINYTTMVSNF
                     SAGQGLFMWDGNWDAANVEKALGQGGAQFGLVPPVEAGGKHVAMGTGNTFAIPAKSKNA
                     DVVAAFLNWIVTDEKARQIVVDVTGASPGGDPAQALPTAQEGSLIAKALELSAEVGDDD
                     GFVDFMANSTAGIYQGSLQPNEQLLLTDKMTPADFLKATQDFYEQDLAAQ"
     gene            2604..3599
                     /locus_tag="EOG37_RS11205"
                     /old_locus_tag="EOG37_11190"
     CDS             2604..3599
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1067: putative ABC
                     transporter permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012039471.1"
                     /locus_tag="EOG37_RS11205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EOG37_11190"
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="WP_220015598.1"
                     /transl_table=11
                     /translation="MSTTDRTIPAGATATAAVPAGPSTRGGGPGRAPTRRRRLGPEARR
                     TATVGWIMLLPAVAAYAAFVVWPLITAVQYSFYKWNGIGTSTFIGLDNYVQIFTDTRLL
                     TPIVNALILVIFFMVIPITAGLALATLLRGMKQGPFASISRTILFLPQIVPLVAAGIAW
                     SWMYAQSGTINSILDAVGLGFLSRSWLADFGTALPAVGLIGSWVLTGLCTVLLLTGMGK
                     IDGSLYEAVRLDGAGFFREFVTITLPGLRQEIAVLVTITVIAALSTFDIIYTTTKGGPG
                     TTTLVPGIEIFRLAFVQSQVGLASAFGVVLLVFVLLLVLPVQRLSRERDR"
     gene            3596..4420
                     /locus_tag="EOG37_RS11210"
                     /old_locus_tag="EOG37_11195"
     CDS             3596..4420
                     /GO_process="GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1069: putative ABC
                     transporter permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012039470.1"
                     /locus_tag="EOG37_RS11210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EOG37_11195"
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="WP_220015599.1"
                     /transl_table=11
                     /translation="MIVNRTELVVGRILLIAALVLTLLPFASMLTAALQSPDSLPNGFS
                     WPTPAYWENFVTAFTVGNIGTLMLSSLFIVVMVVPVSLVCATLAGYSLGNLRVPGGKYV
                     LVAMIIGLTIPFEAIIIPLYYQMTGFGLINTRWAVILPLIGLYMPFSVFWMRAHFVGVP
                     RELSEAARVDGASIWQEFRSIQLPLARPALSALGILLFLWTWNQFLLPLVMIDDPSERT
                     MAGALGAFQGQYIDALPLLFAASLIVMLPTVIVYVIFQRQFIAALLQGAVKG"
     gene            4420..5412
                     /locus_tag="EOG37_RS11215"
                     /old_locus_tag="EOG37_11200"
     CDS             4420..5412
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012039469.1"
                     /locus_tag="EOG37_RS11215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EOG37_11200"
                     /product="glycosyl hydrolase family 32"
                     /protein_id="WP_160478125.1"
                     /transl_table=11
                     /translation="MAFALPGHWVWDSWTAVDGDTTHLFYLHAPTALGDPDLRHRNAAV
                     GHATSTDLVTWTDHGVVLEHGPAGSPDASATWTGSVTRDPSGLWRMSYTGSVFPRDDAG
                     ANVETVLQATSADLHRWVKASVSALSADPRWYETLADGTWREEAWRDPWVERDPAGDGW
                     RMLVTARSRAAASGPDADPLDRGVVGHAVSRDLVTWTAAAPLSAPGAGFAHLEVLQVAE
                     VDGRRVLVFSCAGSDLAGARAGQEGGVFALPLDDDQPFGRPVDIGRARLLHGEGLYAAR
                     IVRTPSGPALLGFEDAGADGSFVGRIPDPVPVRWDAAGLLVAVPAGSAS"
     gene            5409..6620
                     /locus_tag="EOG37_RS11220"
                     /old_locus_tag="EOG37_11205"
     CDS             5409..6620
                     /EC_number="3.-.-.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1053: beta-lactamase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012039468.1"
                     /locus_tag="EOG37_RS11220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EOG37_11205"
                     /product="serine hydrolase"
                     /protein_id="WP_220015600.1"
                     /transl_table=11
                     /translation="MTGAGAAVGAGTRADGVVGWVAPGFEGVRRAFADAVASDVGTGAA
                     LSVRQRGDVVVDLAGGVADDVTGRAWGLDTPSVLFSATKGVMSILVARLVEDGRLRYDQ
                     PVADLWPEYARAGKAGTRVADALAHRAGIAAPHRDWTLSDLVDWDRATALVAAEEPRGE
                     PGTAWAYHAITHGWLTGEIVRRVTGLMPGAWFQALATGPLGVDAWIGIPPEVGERVARM
                     RVGTTLRELTSRQRADVAAGGPDLPLRALTLGGALPLELVGDDAGFSRADVQAAEIPGA
                     GGIGTAHALAAVWSAVVVETAGVRLLDDGTIRLATRPVSGGDEPPAFDVPGPWPRWGMG
                     FQLDSAARRYLGSGSLGHDGAGGQVAFADVEHRVGFAFLTNRMEADDDRGTRIVDALRE
                     ALPR"
     gene            complement(6785..7837)
                     /locus_tag="EOG37_RS11225"
                     /old_locus_tag="EOG37_11210"
     CDS             complement(6785..7837)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_ER (57-345). E-value: 9e-42. Score:
                     135.2. Matches aSDomain:
                     nrpspksdomains_EOG37_RS11225_PKS_ER.1"
                     /codon_start=1
                     /function="NADPH:quinone reductase and related Zn-dependent
                     oxidoreductases"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028: crotonyl-CoA reductase / alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012039467.1"
                     /locus_tag="EOG37_RS11225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EOG37_11210"
                     /product="NADP-dependent oxidoreductase"
                     /protein_id="WP_012039467.1"
                     /sec_met_domain="ADH_N (E-value: 1.6e-06, bitscore: 22.9,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 4.3e-16, bitscore:
                     54.0, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSQVIQSRAGVAAAAERDRAAAAVALAPHGETMRAVVVTETGGPD
                     VLHVADVPVPHRLDSEVLVKVVAAGVNPIDLRLRAGEPGGPTLGILPAVLGRDFSGVVV
                     ESPYEDHALHPGDEVFGLAMVPRMPGSYAPYIAVPSVSLARKPARLSHVEAAATPVSAL
                     TAWGMVVDIGRAHEGQVVLIHAGAGGVGHFAVQFARHFGARVVATGSPRNVDWLAELGA
                     DEVIDRSQVRFEDVLADVDVVIDLVGNCTDDTGTRSLQVLRRGGLLVSAPVRGWPTLVQ
                     DAAAVGVRATHYEVAPDGQKLAVISRLLESGDIKVYVDEVFDLEDAAEAHRHMESGHAR
                     GKVVLNVARG"
     aSDomain        complement(6803..7666)
                     /ASF="ER configuration inconclusive"
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_EOG37_RS11225_PKS_ER.1"
                     /evalue="9.00E-42"
                     /label="EOG37_RS11225_PKS_ER.1"
                     /locus_tag="EOG37_RS11225"
                     /protein_end="345"
                     /protein_start="57"
                     /score="135.2"
                     /tool="antismash"
                     /translation="LDSEVLVKVVAAGVNPIDLRLRAGEPGGPTLGILPAVLGRDFSGV
                     VVESPYEDHALHPGDEVFGLAMVPRMPGSYAPYIAVPSVSLARKPARLSHVEAAATPVS
                     ALTAWGMVVDIGRAHEGQVVLIHAGAGGVGHFAVQFARHFGARVVATGSPRNVDWLAEL
                     GADEVIDRSQVRFEDVLADVDVVIDLVGNCTDDTGTRSLQVLRRGGLLVSAPVRGWPTL
                     VQDAAAVGVRATHYEVAPDGQKLAVISRLLESGDIKVYVDEVFDLEDAAEAHRHMESGH
                     ARGKVVL"
     CDS_motif       complement(7244..7306)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_EOG37_RS11225_0001"
                     /evalue="9.50E-07"
                     /label="PKSI-ER_m5"
                     /locus_tag="EOG37_RS11225"
                     /protein_end="198"
                     /protein_start="177"
                     /score="21.3"
                     /tool="antismash"
                     /translation="GQVVLIHAGAGGVGHFAVQFA"
     gene            complement(8035..8697)
                     /locus_tag="EOG37_RS11230"
                     /old_locus_tag="EOG37_11215"
     CDS             complement(8035..8697)
                     /codon_start=1
                     /function="conserved hypothetical protein"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012039466.1"
                     /locus_tag="EOG37_RS11230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EOG37_11215"
                     /product="YqaJ viral recombinase family protein"
                     /protein_id="WP_012039466.1"
                     /transl_table=11
                     /translation="MLAFPWEDDLAPAAPAPPPPPPHLTRIVAHSSDRVAWLRARSFGI
                     TATDVARLATDASLQAVALEKLYGSGFGGNRYTDHGREREPEIARWVEAEHGIVPSAHL
                     FHAEGQRRHLATPDGVGLRADGRLELAEIKTTAKPWRSIPRNYLRQIWWQQYVLGAERS
                     LIVWEQHVDFVPVHDIPKWKWIDRDEAEIAALVARANDLIALIVRMANAPAGARGLA"
     misc_feature    8866..8876
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.94"
                     /tool="antismash"
     gene            8870..9082
                     /locus_tag="EOG37_RS11235"
                     /old_locus_tag="EOG37_11220"
     CDS             8870..9082
                     /codon_start=1
                     /function="hypothetical protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012039465.1"
                     /locus_tag="EOG37_RS11235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EOG37_11220"
                     /product="hypothetical protein"
                     /protein_id="WP_012039465.1"
                     /transl_table=11
                     /translation="MSLLMEPTRTTAPEVAPAAGGEAASDALLAEAFGFTITHRGAEEE
                     LVMGDVTLCCSTTCSSSGSGHQQPR"
     CDS_motif       8870..9037
                     /prepeptide="leader"
                     /note="peptide class: thiopeptide"
                     /note="predicted sequence:
                     MSLLMEPTRTTAPEVAPAAGGEAASDALLAEAFGFTITHRGAEEELVMGDVTLCCS"
                     /locus_tag="EOG37_RS11235_thiopeptide"
                     /aSTool="thiopeptides"
                     /tool="antismash"
     CDS_motif       9038..9082
                     /prepeptide="core"
                     /locus_tag="EOG37_RS11235_thiopeptide"
                     /peptide="thiopeptide"
                     /predicted_class="Type III"
                     /score="6.10"
                     /molecular_weight="1432.5"
                     /monoisotopic_mass="1431.6"
                     /core_sequence="TTCSSSGSGHQQPR"
                     /aSTool="thiopeptides"
                     /tool="antismash"
                     /leader_sequence="MSLLMEPTRTTAPEVAPAAGGEAASDALLAEAFGFTITHRG
                     AEEELVMGDVTLCCS"
                     /leader_location="[8869:9037](+)"
                     /alternative_weights="1450.5"
                     /alternative_weights="1468.5"
                     /alternative_weights="1486.5"
                     /alternative_weights="1504.6"
                     /alternative_weights="1522.6"
                     /alternative_weights="1540.6"
     gene            9093..10004
                     /locus_tag="EOG37_RS11240"
                     /old_locus_tag="EOG37_11225"
     CDS             9093..10004
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012297986.1"
                     /locus_tag="EOG37_RS11240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EOG37_11225"
                     /product="TOMM precursor leader peptide-binding protein"
                     /protein_id="WP_086507795.1"
                     /transl_table=11
                     /translation="MDSSTTYSVSPRYAVGEVEDTLHLLGGRELVSLKLPSGDAVSAVS
                     RLLSRPFTRADLDRAFAAHAPAVADLVDELVLRDVVVGSPTGSAGSVPDELAHVLDEAR
                     RNGGDRTGLGPVRDAASPARVALVGDMIPSLLTGLAEALPSAELGDEHDADLVIAVGSR
                     PVLREVGARMHAAGRPWLPVHPFDGRFQLVGPVVVPGEGPCLECVALRWASTTPFAADH
                     AAAADAVAVVPRDPSLDAITAGFAARFAARWIHSHDWLVASTVLVIEPKVMEAEAHAVF
                     RVARCGTCGPRPYAGVASPWRA"
     gene            10001..11263
                     /locus_tag="EOG37_RS11245"
                     /old_locus_tag="EOG37_11230"
     CDS             10001..11263
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: YcaO"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015491343.1"
                     /locus_tag="EOG37_RS11245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EOG37_11230"
                     /product="YcaO-like family protein"
                     /protein_id="WP_079534293.1"
                     /sec_met_domain="YcaO (E-value: 2.5e-56, bitscore: 186.6,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSRGGAGVVSPYTGLVEHAHPMAFTPDAIPDALYSGRSADTGFLT
                     GTESERFSMGPGGSRMEARRSCIGEAVERMSLAGAPGGFRAPLGADARQVGPDAFQRFH
                     PTQREDPAFHYERAQAGDLLTWMPARSLHRGDAVHVPAQMVVFDDPHRADGHREPHVEP
                     ATSSGVAAGPHFGFAAGRAVLELIERDAFQRSWLRGSTPPAFDWRGSSRLTDATLRELE
                     RLEELCGRFGASFTVRVLDAAADVPVLLAVMRSDRIGVAVGCAADFRLDRAILNAVREA
                     LHTHNWCLRLLAEPTIDPEDVVEFEDHIRLHCRPSARPLTAALDGSDERVAAIGGPDSW
                     AEVVAGLDREGIEVLLADITAPEVRAAGFHVVRALSPDLVALDVVHAARFLGHPRLYRR
                     WRDGPAIDGPADLVHVPHPFP"
     gene            11322..12290
                     /locus_tag="EOG37_RS11250"
                     /old_locus_tag="EOG37_11235"
     CDS             11322..12290
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: PF00881"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015491342.1"
                     /locus_tag="EOG37_RS11250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EOG37_11235"
                     /product="SagB/ThcOx family dehydrogenase"
                     /protein_id="WP_160447797.1"
                     /sec_met_domain="PF00881 (E-value: 1.3e-16, bitscore: 56.0,
                     seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTIETDATPERAEAATGPSARADPATLASGRSLGSVGPIFSVGG
                     AVDRHAGDPAEDFHEASKITRITHPGWTDVRYAHQMAQEAQGITDAGPGGATSAPRLLP
                     ALPLPRALPLRHELGATLAARRSAEPRTLGRPVELAELATVLRLAYGPRGDGTPGRFVP
                     SGGGLYPLDLHVVARSVVGLEPGIHQLDPLEETLVDVSGLDRDGRLARFRRAAPSLMAP
                     IPETAAVTVVITGSFERSRCKYGLRGYRLTLLEAGHVGQNALLVATALGLPVLGWVGFV
                     DHELDAVLGLDGVTQSSLYAISFGGAEPGARRFAEEEASHD"
     gene            12283..13239
                     /locus_tag="EOG37_RS11255"
                     /old_locus_tag="EOG37_11240"
     CDS             12283..13239
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012297989.1"
                     /locus_tag="EOG37_RS11255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EOG37_11240"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_220015601.1"
                     /transl_table=11
                     /translation="MTDAIELEGITRAFGRTRALDAASFSLAPGLVHALLGPNGSGKTT
                     AIDVLTATRRPDAGRARVLGHDVRRGGPTAALVAVMPQALAFPEYLTVREVLALALVPH
                     AAALTPAAAIDRFDLDRLASRQTGGLSGGERRRVALACVVGAGTPVVVLDEPSAALDIP
                     GRAAVRDAIAAVRDSGRTVLLASHDMEEVAALADTVVCLDHGRVVGHWTAADFRGLAGV
                     RRVGFDATVAEARRLRSSGAVPEAGEEPRGLERIRWVIDTDRSDVVAGLVLAAVPQPRL
                     TVVEPGLGEIVERVLAGGADATPADPSRTEDHAGCAR"
     gene            13236..14018
                     /locus_tag="EOG37_RS11260"
                     /old_locus_tag="EOG37_11245"
     CDS             13236..14018
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012039460.1"
                     /locus_tag="EOG37_RS11260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EOG37_11245"
                     /product="ABC transporter permease"
                     /protein_id="WP_086507966.1"
                     /transl_table=11
                     /translation="MTAAPMPVRPTAARRFAVYRAHVVSELAQNARMPAFVLPLLAYPV
                     LIYAVVGLPQGGPPSARLSVLLGYVLFSVLGTVTFQFGVGVASARESPWERWLFTAPVP
                     AWIRLAAKLTVACVFGVVFVIPVVAVGILAGGVRVDAATLGSVALAVLAGAVPMALLGL
                     AMGYWFPARGALGLANLVYLPLSFAGGLFTGGDTSGTPWESLTVLLPTGAWSTLTSAAT
                     RQDTAVMGIPLILLAAWTVLLGGITLAGYQRTQSANFR"
     gene            14141..15214
                     /locus_tag="EOG37_RS11265"
                     /old_locus_tag="EOG37_11250"
     CDS             14141..15214
                     /GO_function="GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012039459.1"
                     /locus_tag="EOG37_RS11265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EOG37_11250"
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="WP_086506628.1"
                     /transl_table=11
                     /translation="MPQITTPVALFTGQWADLPLEEVARLASGWGFDALEIACSAEHLD
                     VWRAAEDPAYLRGRLEILERHGLQVHALSQHLTGQAVCDDPIDFRHQAILRSKVWGDGQ
                     AEGVRQRAAEELKLTAKAAAALGVTRVTGFTGSRIWPYVAMFPPVPESVIDAGYQDFAD
                     RWNPIIDVFDDEGVRYALEVHPSEIAYDYWTTRRTLEAIGHRPGFGLNWDPSHMMWQGI
                     DPVGFLLDFADRIYHVHAKDTRVTSDGRGGRLGSHLPWGNPRRGWDFVSVGHGDVPFER
                     AFRALRSIGYDGPVSVEWEDAGMDRLHGAPDALARVRSLLWPTPDSLFDSAFANNRDDA
                     PAATSADGSTGTAGSTA"
     gene            15211..16149
                     /locus_tag="EOG37_RS11270"
                     /old_locus_tag="EOG37_11255"
     CDS             15211..16149
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015491338.1"
                     /locus_tag="EOG37_RS11270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EOG37_11255"
                     /product="biopolymer transporter Tol"
                     /protein_id="WP_220015602.1"
                     /transl_table=11
                     /translation="MTLRDGQLARLLVVDVETGAERMVAESAVLHIEAPNWTPDGRWLV
                     VNAEGGLWRLPAPDPEEPDPDLPEPAVDFQAVDLGGVPPINNDHVMSPDGAHVYVSGRD
                     GHLYAIPWNDGAGGDGRRITADRDPALGFKNYLHGVSPDGSMLSVIGGQLDARGEWTTN
                     IHLVPVDGGPTTQLTDDGFPDDGAEFSPDGGWLYFNSERGSDLPGHAQLFTMRTDGTDT
                     HQFTSDERVNWFPHPSPDGEHIVYLSFPPGTLGHPADRDVILRVIDRQSHRTRDLASFP
                     GGQGTINVTSWAPDSRRFAYVAYPFEAPSLT"
     gene            16334..17362
                     /locus_tag="EOG37_RS11275"
                     /old_locus_tag="EOG37_11260"
     CDS             16334..17362
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012039457.1"
                     /locus_tag="EOG37_RS11275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EOG37_11260"
                     /product="TerC family protein"
                     /protein_id="WP_220015603.1"
                     /transl_table=11
                     /translation="MNITTTTWLITIAVTIAFFVYEFFTHVRKPHEPTIGESARWSAFY
                     IGLALIFGVGIGFTSGWDFGGQYFAGYLTEKALSIDNLFVFLLIMTGFAVPRKYQQKVL
                     MIGIVIALIMRAGFIALGAALIENFSWVFYIFGALLFVLAYQQLKGDHGGNAADNMFVR
                     IARRILPVHDEFVGDRFTTKIDGKRFVTPLLLCVIAIGFVDLVFALDSIPAIYGLTNEA
                     YIVFTANAFALMGLRQLYFLIGGLLERLVYLSQGLAVILAFIGAKLVLHAMHVNELPFI
                     NGGEPMLWAPEIPIWFSLLFIGATITVATVASLAKTRGDKQKKDRASVDGETVTRATDE
                     GH"
     misc_feature    17707..17721
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 16.96"
                     /tool="antismash"
     misc_feature    complement(17738..17752)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: medium, score: 20.1"
                     /tool="antismash"
     misc_feature    17751..17765
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 14.71"
                     /tool="antismash"
     misc_feature    17806..17821
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 17.39"
                     /tool="antismash"
     misc_feature    complement(18282..18302)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 18.73"
                     /tool="antismash"
     misc_feature    complement(18436..18451)
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 22.59"
                     /tool="antismash"
     misc_feature    18527..18540
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: medium, score:
                     16.82"
                     /tool="antismash"
     misc_feature    18642..18655
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 13.35"
                     /tool="antismash"
     gene            18919..19692
                     /locus_tag="EOG37_RS11280"
                     /old_locus_tag="EOG37_11265"
     CDS             18919..19692
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015491336.1"
                     /locus_tag="EOG37_RS11280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EOG37_11265"
                     /product="tetratricopeptide repeat protein"
                     /protein_id="WP_220015604.1"
                     /transl_table=11
                     /translation="MPDDPDAPTRARLLWDEGDRAEALALLKEHLREDPRDGDARLALA
                     ELYRELIAPDQAGRWGIAVPGRTTEVERDRLARMIAHSGIADHEIAGFLELPPDAELPA
                     EATALMPAIERHRADFADPARMTKRERKAARYASTPSSFAYEVADVAADLAWWVIGIVF
                     ALGALLVWVAALCGQPVTALARWTGTATLATSALVCLARAYTMRTEEVVRRKREPDTAP
                     VDVDVLPWISGAILLGLVVVALVSEGARSGDPLPF"
     gene            19766..20536
                     /locus_tag="EOG37_RS11285"
                     /old_locus_tag="EOG37_11270"
     CDS             19766..20536
                     /GO_function="GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA]"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015491335.1"
                     /locus_tag="EOG37_RS11285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EOG37_11270"
                     /product="response regulator transcription factor"
                     /protein_id="WP_239529154.1"
                     /transl_table=11
                     /translation="MDPVTTATPSGFQPAAAPQPRLTRADGSPIRVLVVDDEASLTDLL
                     QMALRYEGWQIRTAENGHQALAAAREFKPDAVVLDIMLPDLDGLQVLSRLRADAEDIPV
                     LFLTAKDSLDDRLAGLTAGGDDYVTKPFSLEEVVARLRGLIRRSTLVVSDSVDPVIRVG
                     DLTLDEDSHEVARAGDPIELTATEFELLRYLMRNPRRVLSKLQILDRVWSYDFGGKSSV
                     VEIYISYLRRKIDAGRNPMIHTVRGSGYMLKAAE"
     gene            20623..22209
                     /locus_tag="EOG37_RS11290"
                     /old_locus_tag="EOG37_11275"
     CDS             20623..22209
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012297993.1"
                     /locus_tag="EOG37_RS11290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EOG37_11275"
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="WP_216832983.1"
                     /transl_table=11
                     /translation="MTLRRRLVLSVVGLLALASILIGTVSILALRASLVQEVDQQLQAT
                     AARSSNLIDRDADQYGSFPGAPPGGLGAFGQQVGTISATIVDGVVSGGYIADRDAAEGE
                     PGGAGAVELTQVQSQQLQSVPTDGIPRTVDLGGALGRYRLVGDTAATGATLVTGLPMKP
                     ADDVVEQLIVVISVVAALTLALAAVLGAVIVRRALRPLDRVVDTATHVAALELDRGDVA
                     LEARVPASDTDERTEVGRVGAALNGLLGHVAAALSSRQASEAKVRRFVSDASHELRTPL
                     ASIRGYAELTRRGPHQLPEDVTHSLSRIESESVRMTTIVEDLLLLARLDEGRELESDPV
                     DVTRILLDTVGDASAAGPDHDWDLDLPDDSVSVPGDDARLRQVVVNLLANARTHTPAGT
                     RVVASLAVEGAGPDAHAVIRVTDDGPGIPPELQASLFERFVRGDGSRARSTGGTGLGLA
                     IAQAIVSAHHGAVWVESEPGRTVFGVRLPVARRAVDARSESGAPAGSASDRWAPPSGAP
                     VADRPGPVGGS"
ORIGIN
        1 cgcggcagcg acccgggccg tgccgctgtc cgccggcgtg accggggcga tcgagccgcg
       61 ctcgaccacg ggcatcccca cgaggcgctc gcccggctcg gcgtcgcgca ggacgagacg
      121 aacggcctct cgtcccatct cctcgtgagg gagggcgatg gtcgtgaggc cgggccgcag
      181 gtaggacgcc agctcgtcgt tgtcgaagcc gacgagcgag acgtcgatgc cgacgcggat
      241 cccgcgctcc tggcacgcct ggtacgcccc gaatgccagg cggtcgttca ggcagaggat
      301 cgcgcgggtc ccgggcgccg cgtccaggat cgcgcccgcg gcctcgtagc cggcgtccgg
      361 ctcccagtcc ccgcacgacc gctcggccgc gaagcgcagg ccgagctcgg ccatctccgc
      421 gcggatcccg tgcaggcgac gcgccaccgt ctccgagcgg aagaggctcc gctcggtcgc
      481 gatgtcgctg ccgaggagcg cgatcccatc ggagtggccg gcggcggcga ggaggtcgac
      541 cgcgcggcgt ccgccctcct cctcgtccgg cagcacggag ctgccgtggt gggggctggt
      601 ggcgttgagc atcacgacgt gcgtcgaggc gggcacgtcg gggacgacga gctcccgtgc
      661 gcgcatcgtg gcgaagacga tgccgtcgac ctggcggtcg agcaccgcgg acacggcctc
      721 ggcctcgcgc gcctcttcgc caccggtctc gagcacgagc acgacgtgcc cggcgcgctc
      781 cgcctcgacg agcgcgccgc ggatgaggcc gctcgcgaag cgggtggtgg cgacgacgtc
      841 ggagatgaag ccgatggtga gcgatcggtc ggtgcggagg gcccgggcgc ccatgttggg
      901 gcggtagccg agctcggcgg cggcggctag gacgcggcgg tgggagtcct cggagaagcg
      961 cgtctctggc gtgccgttga ggatctgcga cgccgccgtc ggggagaggc cggcgagccg
     1021 ggccacgtcc gccagggtcg gtcgcttctg gcgcatgtga cgtcctcctc ctcgtgagcg
     1081 tatccggtga tccgtcgacc gcggagatgc cgggttgaca cccggcgtcc ctgcgcgcat
     1141 gatctcctgc aacaggtaaa tggatttacc accagcctgt cacaccgcat gcgccgttgc
     1201 ccgcggctcc cgcacgaccc gccccgcccc cgcatcacct gacgaaggag tcaccgcatg
     1261 tccaccatga gaagggcggg acgcgcggca gcgctgaccg ccgccgccgc gatctcggcg
     1321 ctcgccctcg cgagctgcgc ccccggcagc gcgcccgtcg cctccgcgcc cgccggcgat
     1381 gtgagcaccg cgatcccgac ggacgacgtc acgatccgga tccaggacga gaccggcttc
     1441 ccggtcacgg acgagctgac ggccgagttc acgaagcagc acccgaacgt gaagttcgac
     1501 atcacgcgcg acagcttcca gaacctcctc gcgaacacgc cgcgcctcct cgcgagcgac
     1561 gacgccccgg acctgatccg cctctcgacg ctcggcacca cggtcaagga cgggctcctc
     1621 acgaacctcg acccgtactt cgacgcctac ggctgggacc gcttcccggc gggccagctc
     1681 gcgggtgccc ggatggatga ccagggcgtg cgcggcgagg gctcgctgtg gcagttcggc
     1741 atcggctaca gcgtcacggg catctacatg aaccaggagc tggccgacca ggtgggcatc
     1801 accgagatgc cggccaccat ggacgagctc gaggcggacc tcgcgaaggc gaaggacgcc
     1861 ggcgtgctcc ccatccagac cggcatgcag gacggcgtcg ggaccttcat cctccagtcg
     1921 ctcatcaacc agcagggcga caagcaggac ctcgtcgact ggatgtacaa caagccgggc
     1981 gcgaccatcc agaccgacgc ggcgctcgca ggcgccacga agttccagga ctgggcgaag
     2041 gccgggtacc tcccgccgga cgtcaacgcc atcaactaca cgacgatggt gtcgaacttc
     2101 tcggccggcc aggggctgtt catgtgggac ggcaactggg acgccgcgaa cgtggagaag
     2161 gccctcggcc agggcggcgc gcagttcggc ctcgtgccgc cggtcgaggc gggcgggaag
     2221 cacgtcgcga tgggcacggg caacaccttc gccatcccgg ccaagtcgaa gaacgccgac
     2281 gtcgtcgccg cgttcctgaa ctggatcgtg accgacgaga aggcgcgcca gatcgtcgtc
     2341 gacgtgacgg gcgcgtcgcc cggcggcgac ccggcccagg ccctgccgac cgcccaggag
     2401 ggcagcctca tcgcgaaggc cctcgagctg tccgccgagg tcggcgacga cgacggcttc
     2461 gtcgacttca tggcgaacag cacggccggc atctaccagg gctcgctcca gccgaacgag
     2521 cagctgctgc tcaccgacaa gatgacgccc gcggacttcc tgaaggccac gcaggacttc
     2581 tacgagcagg acctcgccgc acagtgagca ccacggatcg caccatcccc gcgggggcga
     2641 cggcgaccgc cgccgtcccc gcggggccgt ccacgcgcgg cggcgggccc gggcgcgcgc
     2701 ccacgcggcg ccgccggctc ggccccgagg cccgtcgcac cgcgacggtc ggctggatca
     2761 tgctgctgcc ggccgtcgcg gcctacgctg cgttcgtcgt ctggccgctc atcacggcgg
     2821 tgcagtactc gttctacaag tggaacggga tcggcacctc gaccttcatc ggcctcgaca
     2881 actacgtgca gatcttcacg gacaccaggc tgctgacgcc catcgtcaac gcgctgatcc
     2941 tcgtgatctt cttcatggtg atccccatca ccgcgggcct cgccctcgcc acgctcctgc
     3001 gcgggatgaa gcagggcccg ttcgcgtcga tctcgcgcac catcctgttc ctgccgcaga
     3061 tcgtcccgct cgtcgcggcg ggcatcgcgt ggtcgtggat gtacgcgcag tccggcacca
     3121 tcaactccat cctcgacgcg gtggggctcg gcttcctgtc ccgctcctgg ctcgccgact
     3181 tcggcacggc gctgcccgcg gtcgggctca tcggatcctg ggtgctcacg ggcctctgca
     3241 ccgtgctgct gctcacgggc atgggcaaga tcgacggctc gctctacgag gccgtgcggc
     3301 tcgacggtgc cggcttcttc cgcgagttcg tcaccatcac cctgccgggc ctccggcagg
     3361 agatcgcggt gctcgtgacc atcacggtca tcgccgccct gagcacgttc gacatcatct
     3421 acacgaccac caagggcggg ccgggcacca cgacgctcgt gcccggcatc gagatcttcc
     3481 ggctcgcgtt cgtgcagagc caggtgggcc tcgcgtccgc gttcggcgtg gtgctgctcg
     3541 tgttcgtgct gctgctcgtg ctccccgtcc aacgactctc gagggagcgc gaccgatgat
     3601 cgtcaaccgc accgagctcg tcgtgggccg catcctgctg atcgcggccc tcgtgctcac
     3661 cctgctgccc ttcgccagca tgctcaccgc cgcgctgcag tcgcccgact cgctgcccaa
     3721 cggcttctcc tggccgacgc ccgcctactg ggagaacttc gtgacggcgt tcacggtggg
     3781 gaacatcggc acgctgatgc tctcgagcct gttcatcgtg gtgatggtcg tgcccgtcag
     3841 cctcgtctgc gcgacgctcg cgggctactc gctcgggaac ctccgggtgc ccggcgggaa
     3901 gtacgtgctc gtcgccatga tcatcgggct gaccatcccg ttcgaggcga tcatcatccc
     3961 gctctactac cagatgacgg gcttcggcct catcaacacc aggtgggcgg tcatcctccc
     4021 gctcatcggg ctgtacatgc cgttcagcgt gttctggatg cgcgcgcact tcgtcggcgt
     4081 gccgcgggag ctgtcggagg ccgcgcgcgt ggacggcgcg agcatctggc aggagttccg
     4141 gagcatccag ctgccgctcg cgcggccggc gctctcggcg ctcgggatcc tcctgttcct
     4201 ctggacctgg aaccagttcc tgctgccgct cgtgatgatc gacgacccga gcgagcgcac
     4261 catggccggg gcgctcggcg cgttccaggg ccagtacatc gacgcgctgc cgctgctgtt
     4321 cgcggcgtcg ctcatcgtga tgctgcccac ggtgatcgtg tacgtcatct tccagcggca
     4381 gttcatcgcg gcgctgctgc agggcgcggt gaagggctga tggcgttcgc gctgcccggg
     4441 cactgggtct gggactcgtg gaccgcggtc gacggcgaca cgacgcacct cttctacctg
     4501 cacgcgccga ccgcgctcgg ggatccggac ctgcgacacc ggaacgccgc cgtgggccac
     4561 gcgacctcga ccgacctcgt cacgtggacc gaccacggcg tcgtcctcga gcacgggccg
     4621 gccgggtcgc cggacgcgtc ggcgacgtgg acgggcagcg tgacgcgcga cccgtcgggg
     4681 ctctggcgga tgtcgtacac gggctcggtg ttcccgaggg acgacgcggg cgcgaacgtg
     4741 gagaccgttc tgcaggcgac ctcggccgac ctgcaccggt gggtgaaggc gagcgtatcc
     4801 gcgctgtcgg ccgacccgcg ctggtacgag acgctcgccg acggcacgtg gcgcgaggag
     4861 gcgtggcggg atccctgggt cgagcgggac cccgcgggcg acggctggcg catgctcgtc
     4921 accgcgcggt cgcgggccgc cgcgtcaggt ccggacgcgg atccgctcga ccgcggcgtc
     4981 gtggggcacg ccgtctcgcg cgacctcgtg acctggaccg ccgcggcgcc gctcagcgcg
     5041 cccggcgcag ggttcgcgca cctcgaggtg ctgcaggtcg cggaggtcga cggccggcgg
     5101 gtgctcgtgt tctcatgcgc gggatccgac ctcgcgggcg cgcgagccgg gcaggagggc
     5161 ggcgtcttcg cgctgccgct cgacgacgac cagccgttcg gccgccccgt cgacatcggg
     5221 cgcgcccggc tcctgcacgg cgaggggctg tatgccgcgc gcatcgtccg gacgccgtcg
     5281 ggtccggcgc tcctcggctt cgaggacgcc ggcgcggacg gctcgttcgt cggccgcatc
     5341 ccggatccgg tgcccgtgcg atgggacgcg gccgggctgc tggtcgcggt gcccgccggg
     5401 tccgcgtcgt gaccggcgcg ggggcggccg tcggcgccgg gacgcgcgcc gacggcgtgg
     5461 tcggctgggt cgcgcccggc ttcgagggcg tgcggcgcgc gttcgcggac gccgtcgcgt
     5521 ccgacgtcgg cacgggcgcc gcgctctccg tccggcagcg cggcgacgtg gtggtggacc
     5581 tcgcgggcgg cgtcgccgac gacgtgaccg gccgcgcgtg ggggctcgac accccgagcg
     5641 tgctgttctc cgcgaccaag ggggtcatgt cgatcctggt cgcgcgcctc gtggaggacg
     5701 ggcggctgcg ctacgaccag ccggtcgccg atctgtggcc ggagtacgcg cgcgccggca
     5761 aggcggggac ccgggtcgcg gacgcgctcg cgcaccgtgc cgggatcgcg gcgccgcacc
     5821 gggactggac gctgtccgac ctcgtcgact gggatcgcgc gaccgcgctc gtcgcggcgg
     5881 aggagccgcg cggggagccc ggcacggcgt gggcctacca cgccatcacg cacggttggc
     5941 tgacgggcga gatcgtgcgg agggtcaccg ggctcatgcc gggcgcgtgg ttccaggcgc
     6001 tcgcgaccgg gccgctgggg gtggacgcct ggatcgggat cccgcccgag gtcggcgagc
     6061 gcgtcgcgcg catgcgcgtg ggcacgacgc tgcgggagct cacctcccgg cagcgcgcgg
     6121 atgtcgcggc gggcggcccc gacctgccgc tgcgcgcgct cacgctcggc ggcgcgctgc
     6181 cgctggagct cgtgggcgac gacgcgggct tctcccgcgc ggacgtgcag gcagcggaga
     6241 tccccggcgc cggcggcatc ggcacggcgc acgcgctcgc cgccgtctgg tcggccgtgg
     6301 tcgtggagac cgcgggcgtg cgcctgctcg acgacggcac gatccgcctc gcgacccgtc
     6361 ccgtctccgg cggcgacgag ccgcccgcgt tcgacgtgcc gggcccgtgg ccacggtggg
     6421 gcatgggctt ccagctcgac tcggccgcgc gccgctacct cggatccggc agcctcggcc
     6481 acgacggcgc tggcggccag gtcgccttcg ccgacgtcga gcaccgggtc ggcttcgcgt
     6541 tcctcaccaa ccggatggag gccgacgacg accgcgggac ccggatcgtc gacgcgctac
     6601 gggaggcgct gccgcgctga gcgggcgcgg cgggcgcgac cggcgagggt cagccccgcg
     6661 ccacgtcgag cacgtccttg cctgtcggcg agggtcagcc ccgcgccacg tcgagggcga
     6721 tcttgcctgt cggcgagggt cggccccgcg ccacgtcgag ggcgatcttg cctgtcggcg
     6781 ggggtcagcc ccgcgccacg ttgaggacga ccttgccgcg agcgtgcccg ctctccatgt
     6841 ggcggtgcgc ctcggcggcg tcctccaggt cgaagacctc gtcgacgtag accttgatgt
     6901 cgccggactc cagcaggcgc gagatcaccg cgagcttctg cccgtcgggc gcgacctcgt
     6961 agtgggtggc gcgcacgccg accgcggccg cgtcctgcac gagcgtcggc cagccgcgga
     7021 cgggcgcgct gaccaggagg ccgccacgac ggaggacctg cagcgagcgg gtgccggtgt
     7081 cgtcggtgca gttgccgacc aggtcgatca ccacgtccac gtcggcgagc acgtcctcga
     7141 agcgcacctg cgagcggtcg atgacctcgt cggcgccgag ctccgccagc cagtcgacgt
     7201 tgcggggcga gcccgtcgcg accacgcgcg cgccgaagtg gcgcgcgaac tggaccgcga
     7261 agtggccgac gccgcccgcg cccgcatgga tcaggacgac ctgaccctcg tgcgccctgc
     7321 cgatgtcgac gaccatgccc cacgcggtga gggcgctcac gggcgtcgcc gcggcctcca
     7381 cgtgcgagag gcgcgcgggc ttccgggcga ggctcacgct cgggacggcg atgtacgggg
     7441 catagctgcc gggcatccgc ggcaccatcg cgaggccgaa cacctcgtcg cccggatgca
     7501 gcgcgtggtc ctcgtagggc gactcgacga cgacgccgct gaagtcgcgg ccgagcaccg
     7561 cgggcaggat gccgagcgtc gggccgccgg gctcgcccgc gcggagacgc aggtcgatgg
     7621 ggttcacgcc cgcggcgacg accttcacga gcacctcgga gtcgaggcgg tgcggcaccg
     7681 gcacgtccgc gacgtgcagc acgtcgggcc ctccggtctc cgtgacgacg accgcgcgca
     7741 tggtctcccc gtggggcgcc agggcgacgg cggccgccgc ccgatcccgc tcggccgcgg
     7801 cggcgacgcc ggctctcgac tggatgacct ggctcatcgt gcgacccctc ctcggaacgc
     7861 ggcggcaagg tggatcccac cggcccccgc tcgtccagtg aagccgccga gtgagtcggg
     7921 cgtgtttccg cggtgttccc cgggcgagaa gaatgcggag ggcactcgcc gacggcgacg
     7981 gcggcggcga cggcgcgcga accgggccgg gccgggcctc gcaggcagcg ccgctcaggc
     8041 caggccgcgg gctcccgccg gcgcgttcgc catccgcacg atgagcgcga tgaggtcgtt
     8101 cgcgcgcgcc acgagcgcgg ctatctccgc ctcgtcgcgg tcgatccact tccacttcgg
     8161 gatgtcgtgc acgggcacga agtccacgtg ctgctcccag acgatgagcg agcgctcggc
     8221 gccgagcacg tactgctgcc accagatctg gcgcaggtag ttgcgcggga tgctgcgcca
     8281 cggcttcgcg gtcgtcttga tctccgcgag ctcgagccgg ccgtctgccc ggaggcccac
     8341 gccgtcgggg gtcgccaggt ggcggcgctg gccctccgcg tggaacaggt gcgcgctcgg
     8401 gacgatgccg tgctccgcct cgacccagcg ggcgatctcg ggctcgcgct cccggccgtg
     8461 gtcggtgtag cggttgccgc cgaagccgga tccgtagagc ttctcgagcg cgacggcctg
     8521 cagcgacgcg tcggtcgcaa ggcgtgcgac gtcggtcgcg gtgatgccga agctgcgggc
     8581 gcggagccag gcgacgcgat ccgacgagtg ggcgacgatg cgcgtcaggt gcggtggggg
     8641 aggaggcggc gcgggtgctg cgggggcgag gtcgtcctcc caggggaagg ccagcatctc
     8701 gtccgtcacg ggctccaggg tacgcgtcgg atccgacccg ggccgcctcg acgcgggcgg
     8761 atcgtgccgc ctcgcggatg ggttgtcaac aggtgatgcg catatgacca gggcacggaa
     8821 gatcgtgcta gaaaggcgcc gtcccaccca cccagaggaa ggaacggcaa tgtcactgct
     8881 catggaaccg acgcgcacca ccgcacccga ggtcgcgccc gcggccggag gcgaggcggc
     8941 gtccgacgcg ctgctggcgg aggccttcgg cttcaccatc acgcaccgcg gcgcggagga
     9001 ggagctcgtg atgggcgacg tcaccctgtg ctgcagcacg acgtgctcgt cgagcggcag
     9061 cggccaccag cagcctcgct gatcgcccgc gcatggattc gtcgaccacg tactcggtga
     9121 gtccccgcta cgccgtcggg gaggtggagg acaccctcca cctcctcggc ggtcgcgagc
     9181 tggtctccct gaagctgccc tcgggcgacg ccgtctccgc ggtgtcgcgc ctcctctccc
     9241 gtcccttcac ccgtgcggac ctcgaccggg ccttcgccgc gcacgccccc gccgtggcgg
     9301 acctggtcga cgagctcgtg ctgcgcgacg tcgtggtcgg gtcgccgacc ggctccgcgg
     9361 gatccgtccc cgacgagctc gcgcacgtcc tcgacgaggc gcggcgcaac ggcggcgacc
     9421 gcaccgggct cggtcccgtg cgcgacgccg cgtcgcccgc gcgggtcgcg ctcgtgggcg
     9481 acatgatccc gtcgctgctc acgggcctcg cggaggccct cccctcggcc gagctcggcg
     9541 acgagcacga cgccgacctg gtcatcgcgg tcggctcgcg accggtcctc cgcgaggtcg
     9601 gcgcgcgcat gcacgccgcg gggcgcccgt ggctccccgt gcacccgttc gacggccgct
     9661 tccagctcgt cgggccggtg gtcgtgcccg gcgaggggcc gtgcctggag tgcgtcgcgc
     9721 tgcgctgggc gtctaccacg ccgttcgccg cggatcacgc cgcggcggcc gacgcggtcg
     9781 ccgtcgtgcc gcgcgacccg agcctggacg ccatcacggc cgggttcgcc gcgcgcttcg
     9841 ccgcccggtg gatccactcg cacgactggc tcgtggccag caccgtgctc gtcatcgagc
     9901 ccaaggtcat ggaggcggag gcgcacgccg tgttccgcgt ggccaggtgc ggcacgtgcg
     9961 gcccccgccc ctacgccggc gtggcctcgc cgtggcgggc atgagccgcg gcggggcggg
    10021 cgtcgtcagc ccgtacacgg ggctcgtgga gcacgcgcat cccatggcct tcacgcccga
    10081 cgccatcccc gacgccctct actcgggccg ctccgcggac accgggttcc tcaccggcac
    10141 ggagtccgag cgcttcagca tggggccggg cggatcccgg atggaggcgc gccgctcatg
    10201 catcggcgag gcggtggagc gcatgtcgct cgcgggagcg cccggcgggt tccgcgcgcc
    10261 cctcggcgcc gacgcccgcc aggtggggcc ggacgccttc cagcgcttcc acccgacgca
    10321 gcgcgaggat ccggccttcc actacgaacg cgcccaggcg ggcgacctcc tcacctggat
    10381 gccggcgcgg tcgctgcacc ggggcgacgc ggtgcacgtg cccgcgcaga tggtggtgtt
    10441 cgacgacccg caccgcgcgg acgggcaccg ggagccgcac gtggagccgg ccacctcgtc
    10501 cggcgtcgcg gccgggccgc acttcgggtt cgccgcgggc cgcgccgtgc tggagctcat
    10561 cgagcgcgac gcgttccagc gctcgtggct ccgcggatcc acgcccccgg ccttcgactg
    10621 gcgcggcagc tcccggctca ccgacgcgac gctccgggag ctcgagcgcc tggaggagct
    10681 gtgcggccgg ttcggcgcgt cgttcacggt gcgcgtgctt gatgcggcag ccgacgtgcc
    10741 cgtgctgctc gcggtcatgc gcagcgatcg catcggcgtc gcggtgggct gcgcggccga
    10801 cttccggctc gaccgggcga tcctcaacgc ggtccgcgag gcgctgcaca cgcacaactg
    10861 gtgcctgcgg ctgctcgcgg agccgaccat cgaccccgag gacgtggtcg agttcgagga
    10921 ccacatccgg ctgcactgcc gcccgtccgc gcgcccgctc acggccgcgc tcgacggctc
    10981 ggacgaacgg gtcgcggcca tcgggggccc ggacagctgg gcggaggtcg tcgccgggct
    11041 cgaccgcgag ggcatcgagg tgctgctcgc ggacatcacg gcgcccgagg tgcgcgcggc
    11101 cggcttccac gtggtgcgcg cgctgagccc cgacctcgtg gcgctcgacg tggtgcacgc
    11161 cgcgcggttc ctcgggcacc cgcgcctcta ccggcggtgg cgcgacgggc ccgcgatcga
    11221 cgggccggcc gacctcgtcc acgtcccgca cccgttcccg tgacgggcgg caccgcccgt
    11281 ccccgccgcc gtcccaccgc ccgtcgcacc aggaggatcc catgagcacc atcgagaccg
    11341 acgccacccc cgagcgcgcg gaggccgcga cgggtccgtc cgcgagggcg gatcccgcca
    11401 ccctcgcgtc cgggcgctcc ctcgggagcg tggggccgat cttcagcgtc gggggcgccg
    11461 tcgaccggca tgcgggcgac cccgcggagg acttccacga ggcgtcgaag atcacgcgga
    11521 tcacccaccc cggctggacc gacgtgcggt acgcgcacca gatggcgcag gaggcgcagg
    11581 gcatcacgga cgccgggccg ggcggggcca cctccgcgcc gcggctgctc ccggccctgc
    11641 ccctcccgcg cgcgctcccg ctccggcacg agctgggcgc gacgctggcc gcgcgccggt
    11701 cggccgagcc gcgcacgctc gggcggccgg tcgagctggc cgagctcgcc accgtgctgc
    11761 gcctcgccta cgggccgcgc ggcgacggca cgcccgggcg gttcgtgccc tcgggcggcg
    11821 ggctgtaccc gctcgacctg cacgtggtcg cgcggtcggt cgtggggctc gagccgggga
    11881 tccaccagct cgacccgctc gaggagacgc tcgtcgacgt gtccgggctc gaccgcgacg
    11941 ggcggctcgc gcggttccgc cgcgcggcgc cgtcgctcat ggcgccgatc ccggagacgg
    12001 cggcggtcac cgtcgtcatc acgggcagct tcgagcgctc gcgctgcaag tacgggctcc
    12061 ggggctaccg gctcaccctg ctggaggccg ggcacgtggg gcagaacgcg ctcctggtcg
    12121 ccaccgcgct ggggctgccg gtgctgggct gggtgggctt cgtcgaccac gagctcgacg
    12181 cggtgctcgg gctcgacggg gtgacgcagt cgtccctgta cgcgatctcg ttcggcggcg
    12241 cggagccggg cgcgcggcgc ttcgccgagg aggaggcatc ccatgactga cgcgatcgag
    12301 ctcgagggga tcacccgcgc cttcggccgg acgcgcgcgc tcgacgccgc gtccttctcc
    12361 ctcgcgccgg ggctcgtgca cgcgctgctc gggccgaacg gatccggcaa gaccaccgcc
    12421 atcgacgtgc tcaccgccac ccggcgcccg gatgcgggcc gggcgcgcgt gctcggccac
    12481 gacgtgcgcc gcggcggtcc cacggcggcg ctcgtcgcgg tcatgccgca ggcgctcgcc
    12541 ttccccgagt acctcacggt gcgcgaggtg ctggcgctcg ccctcgtgcc gcatgcggcc
    12601 gcgctcaccc cagccgccgc gatcgaccgc ttcgacctcg accgcctcgc gtcgcgccag
    12661 accggcggcc tcagcggcgg agagcggcgg cgcgtcgcgc tcgcgtgcgt ggtcggcgcg
    12721 gggacgcccg tcgtggtgct cgacgagccc tccgcggcgc tcgacatccc gggccgggcc
    12781 gccgtgcgcg acgccatcgc cgcggtccgc gactccgggc gcaccgtgct cctcgcctcg
    12841 cacgacatgg aggaggtcgc ggcgctcgcc gacacggtcg tctgcctcga ccatgggcgc
    12901 gtcgtcggcc actggaccgc cgccgacttc cgcggtctgg ccggcgtccg tcgggtcggc
    12961 ttcgacgcga ccgtcgccga ggcgcggcgc ctgcggtcgt ccggcgcggt gcccgaggcg
    13021 ggggaggagc cgcgcggcct cgagcggatc cggtgggtca tcgacaccga ccgctccgac
    13081 gtcgtcgccg ggctggtgct cgccgccgtg ccgcagcccc gcctcacggt cgtcgagccc
    13141 gggctcggcg agatcgtgga gcgcgtgctg gcgggcggcg cggacgcgac ccccgccgat
    13201 ccgtcgcgca ccgaggatca cgcggggtgc gcccgatgac cgccgcgccg atgccggtcc
    13261 gccccaccgc agcccgccgg ttcgccgtct accgcgccca cgtcgtgagc gagctcgcgc
    13321 agaacgcgcg catgccggcc ttcgtgctgc cgctcctcgc ctaccccgtg ctcatctacg
    13381 cggtcgtcgg tctgccgcag ggcggcccgc cgagcgcgcg gctcagcgtc ttgctcggct
    13441 acgtgctgtt ctcggtgctc ggcacggtga cgttccagtt cggcgtcggg gtcgcatcgg
    13501 cccgggagtc gccgtgggag cggtggctgt tcacggcgcc ggtgcccgcg tggatccggc
    13561 tggcggcgaa gctcacggtc gcgtgcgtct tcggcgtcgt gttcgtgatc ccggtggtcg
    13621 cggtcgggat cctcgcgggc ggcgtccggg tggacgcggc gacgctcgga tccgtggcgc
    13681 tcgccgtcct ggccggcgcc gtgccgatgg cgctgctcgg cctcgcgatg ggctactggt
    13741 tccccgcccg cggcgcgctc ggcctggcca acctcgtgta cctgcccctg tcgttcgcgg
    13801 gcggcctgtt cacgggcggc gacacgagcg gcacaccctg ggagtcgctc acggtgctgc
    13861 tgccgaccgg cgcgtggagc acgctgacga gcgcggcgac ccggcaggac acggcggtca
    13921 tggggatccc gctgatcctc ctcgcggcgt ggacggtgct gctcggcggc atcaccctcg
    13981 cgggctacca gcgcacgcag tcggcgaact tccgctgacg gccacccgtg agcgggcgcg
    14041 gcccggtgtg tagcgtggat cccgcgcgcc gtcaccgggc cgcgccaccg cacgcaccgc
    14101 acgccacgca ccgcaccgtc accgtcgacg agagggaacc atgccccaga tcaccacccc
    14161 cgtagcgctc ttcaccggcc agtgggccga cctgccgctg gaggaggtcg cccggctcgc
    14221 gagcggctgg ggcttcgacg ccctcgagat cgcgtgctcc gccgagcacc tcgacgtgtg
    14281 gcgcgcggcc gaggatccgg cgtacctccg cggccgcctc gagatcctcg agcgccacgg
    14341 cctccaggtg cacgcgctct cacagcacct caccggccag gccgtgtgcg acgacccgat
    14401 cgacttccgg caccaggcga tcctccgctc caaggtctgg ggcgacggcc aggcggaggg
    14461 cgtgcgccag cgcgccgccg aggagctgaa gctcaccgcg aaggcggccg ccgccctcgg
    14521 ggtcacgcgc gtgacgggct tcaccggatc ccgcatctgg ccgtacgtcg cgatgttccc
    14581 gcccgtgccc gagtcggtca tcgacgccgg ctaccaggac ttcgccgacc gctggaaccc
    14641 gatcatcgac gtgttcgacg acgagggcgt gcggtacgcg ctcgaggtgc acccgagcga
    14701 gatcgcctac gactactgga ccacgcgccg cacgctcgag gccatcgggc accgccccgg
    14761 cttcggcctc aactgggatc cgagccacat gatgtggcag ggcatcgacc cggtgggctt
    14821 cctcctcgac ttcgccgacc ggatctacca cgtgcacgcc aaggacacgc gcgtcacgtc
    14881 cgacggtcgc ggtggccggc tcggatccca cctcccgtgg ggcaacccgc gccggggctg
    14941 ggacttcgtc tcggtcggcc acggcgacgt cccgttcgag cgcgccttcc gggccctgcg
    15001 cagcatcggc tacgacggtc ccgtctccgt cgagtgggag gatgcgggga tggaccgcct
    15061 gcacggagca cccgacgccc tcgcgcgggt gcgctccctc ctctggccga cgcccgacag
    15121 cctcttcgac tcggcgttcg cgaacaaccg ggacgacgcg cccgccgcga cgtccgccga
    15181 cggatccacc ggcaccgccg gatccaccgc gtgacgctgc gcgacggcca gctggcccgc
    15241 ctcctcgtcg tcgacgtgga gacgggcgcc gagcgcatgg tcgccgagtc ggccgtgctg
    15301 cacatcgagg cgccgaactg gacgcccgac ggccgctggc tcgtcgtcaa cgcggagggc
    15361 gggctctggc ggctgccggc gcccgacccg gaggagccgg atcccgacct gcccgagccc
    15421 gcggtcgact tccaggcggt cgacctcggc ggcgtcccgc cgatcaacaa cgaccacgtc
    15481 atgtcgcctg acggcgcgca cgtctacgtc tccggccgcg acggtcacct ctacgccatc
    15541 ccgtggaacg acggcgcggg cggcgacggc cgacggatca cggcggaccg ggatccggcg
    15601 ctcggcttca agaactacct gcacggcgtc tcgcccgacg gctcgatgct cagcgtcatc
    15661 ggcggccagc tcgacgcgcg cggcgagtgg accacgaaca tccacctcgt gcccgtcgac
    15721 ggtggcccca ccacgcagct caccgacgac ggcttccccg acgacggcgc cgagttctcg
    15781 cccgacggcg gctggctcta cttcaactcc gagcgcggat ccgacctccc gggccacgcc
    15841 cagctgttca cgatgcgcac cgacggcacc gacacgcacc agttcacctc cgacgagcgc
    15901 gtcaactggt tcccgcaccc gtcgcccgac ggcgagcaca tcgtctacct gtccttcccg
    15961 cccggcacgc tcggccaccc ggccgaccgc gacgtgatcc tccgcgtcat cgaccggcag
    16021 agccaccgca cgcgcgacct cgcgtccttc cccggcggcc agggcaccat caacgtcacc
    16081 agctgggcgc ccgactcgcg ccggttcgcg tacgtcgcct acccgttcga ggcgccgagc
    16141 ctgacttgac ccggccggca ggcggccggg cggtcctgcg actccgcgcg caggcggccc
    16201 gcggcacgca cgatccgcgg agcgtaggcg caggcatttc cccggtgtga ggagatcccg
    16261 cgtgggatca tggatgcgtc cgcgcgccac ctagccgttc cgattcccgt cggcctcatc
    16321 accggagacc cccgtgaaca tcaccacgac cacctggctc atcacgatcg cggtcaccat
    16381 cgcgttcttc gtctacgagt tcttcaccca cgtgcgcaag ccgcacgagc ccaccatcgg
    16441 cgagtccgcc cgctggtcgg ccttctacat cggcctcgcg ctgatcttcg gcgtcggcat
    16501 cggcttcacc agcggctggg acttcggcgg ccagtacttc gccggctacc tcaccgagaa
    16561 ggccctgtcg atcgacaacc tgttcgtgtt cctgctgatc atgaccgggt tcgccgtgcc
    16621 gcggaagtac cagcagaagg tgctgatgat cggcatcgtc atcgcgctga tcatgcgcgc
    16681 cggcttcatc gcgctgggcg ccgcgctcat cgagaacttc tcgtgggtct tctacatctt
    16741 cggcgcgctg ctgttcgtgc tcgcgtacca gcagctgaag ggcgaccacg gcggcaacgc
    16801 ggcggacaac atgttcgtgc gcatcgcccg ccggatcctc cccgtccacg acgagttcgt
    16861 cggcgaccgc ttcaccacga agatcgacgg caagcgcttc gtcaccccgc tgctgctctg
    16921 cgtcatcgcc atcggcttcg tcgacctggt gttcgcgctc gactcgatcc ccgccatcta
    16981 cggcctcacg aacgaggcgt acatcgtctt caccgcgaac gccttcgcgc tgatgggcct
    17041 gcgccagctg tacttcctca tcggcggcct gctcgagcgc ctcgtctacc tgtcgcaggg
    17101 tctcgccgtg atcctcgcgt tcatcggcgc gaagctcgtg ctgcacgcga tgcacgtcaa
    17161 cgagctgccc ttcatcaacg gcggcgagcc gatgctgtgg gcgcccgaga tcccgatctg
    17221 gttctcgctc ctcttcatcg gtgcgaccat cacggtcgcc accgtcgcga gcctcgcgaa
    17281 gacccgcggc gacaagcaga agaaggaccg cgcgagcgtg gacggcgaga ccgtcacgcg
    17341 cgcgacggac gaggggcact agggcctcgc acctccgcac gatccgggcc cggcgcacca
    17401 cgcgccgggc ccgtcgtcgt ccgaaaagta gaccctgagg gaaacgaggc ctgaagtcca
    17461 gcgtccagct caagccatta gctacgagag tcggtctaag attaaagtag ccgaatggag
    17521 ttgtttcatg cgttttcttg gacgaggact acaggatgcc gtccgcagta gactgaagcg
    17581 gaggggccga ggtaagcaat cacttaagtt acctcccttc ctattgagct tggtcgtagt
    17641 tttcgttctc gcgaccgcct tgctctgggg gatcttcgta gcttacggac gtctggctgg
    17701 aaacgatgta tctctttttg atccaggcgt cggctctatc gagactgttg atctttatga
    17761 cattgtgcgt tccgccgtaa cgaccgcggg ggtttttgcc ggggtttttg caattgtcta
    17821 ctcatatcgc aagcagaagg tacaggaagc tgccagtatc cgagaagatg acgcgcagct
    17881 cgccgaccgc tataaaagcg cggcggaaca gctgggtcat gacaaggagt cggtacgatt
    17941 cgcgggtatt tatgctctat caagattggc cgatgactgg aatgagcagc ggcaggagtg
    18001 catagatgtc ttgtgcgcgt acttgcgtct ccctgagccc tcggactctg ccgaccgagc
    18061 gagggaggcg gttctacgcc gagccgtcct cagccagatc gctacgcata cagaggccac
    18121 tccgcgaggc ccgggccttt ggagcagcat gcggtttgac ttatctggtg cctctctgcc
    18181 gcgatttgcc ttccaatatt gcacctttga tgagttcatt ttagatggcg cccatctcac
    18241 ggacgaactg gagttccgac ggtgtcgcat cgggactcgc ctaagcctcc aatcgacccg
    18301 aatatcgggt aatttgagac tgggcataag gggcagggga gctagcattt ttgcatggga
    18361 cgcccgcctt gaagccggtg cgactctctg gctaacagaa acctcaacca aaagcacggt
    18421 ggatgatttt ccgaggttta cttatggaaa tggattcgta gcggattcgg ctgagcttcg
    18481 cattgaaata ggtcctggaa caaaggcaag gcaattcgat ttctggggca cgacggttgc
    18541 gggtcgtctc gccctctatg gaacaggtcg ggattgtcaa gatggtgcta tacgtctcaa
    18601 agatgtggtt actgagggag ggggcatggt cgggatgcag gtcgagttat tcgaagctca
    18661 gggcgtagtt aagcctggtc cagagaacct caaagctcga gttggaacct tcaccgtagg
    18721 ggagtgggag gtagtcgaag acgagtaggc ggaacgcctc gctagtcaat gtttcgaaga
    18781 cccagagtca agctcatcta gttagggcct catttgtgtc aatcgtgccc attggcgggc
    18841 cgggtccagg ggcttagacc ggacgggcgc ccgtgcgctg cccgctcgca gcgcgcgccg
    18901 gcctggcagc atcggccggt gcccgacgat cccgacgccc cgacccgcgc ccgcctgctc
    18961 tgggacgagg gcgatcgagc cgaggcgctc gccctcctca aggagcacct gcgcgaggac
    19021 ccccgcgacg gcgacgcccg actcgcgctc gcggagctgt accgcgagct catcgcgccc
    19081 gaccaggccg gtcggtgggg gatcgccgtc cccggccgga ccacggaggt cgagcgcgac
    19141 cggctcgcgc gcatgatcgc gcactcgggg atcgcggacc acgagatcgc cggcttcctc
    19201 gagctgccgc ccgacgccga gctgcccgcc gaggcgaccg cgctgatgcc cgcgatcgag
    19261 cggcaccgcg ccgacttcgc cgacccggcg cgcatgacga agcgcgagag gaaggcggcg
    19321 cgctacgcga gcaccccgtc ctccttcgcc tacgaggtgg cggatgtcgc ggcagacctc
    19381 gcgtggtggg tcatcgggat cgtcttcgcc ctgggcgccc tgctcgtgtg ggtggccgcg
    19441 ctgtgcggtc agccggtcac ggcgctcgcc cgctggacgg gcaccgccac gctcgcgacg
    19501 tcggcgctcg tctgcctcgc gcgcgcctac acgatgcgga cagaggaggt ggtccggcgc
    19561 aagcgcgaac cggacaccgc tcccgtcgac gtcgacgtgc tcccgtggat cagcggcgcg
    19621 atcctgctcg gcctcgtcgt ggtggcgctc gtcagcgagg gcgcgcggag cggcgacccc
    19681 ctcccgttct gaggtcacgc gtcgggctgg ccgacgaagc ccgcgcatgg ccgcctcatg
    19741 ggcgcttcat aggaacatcc gcagaatgga tcccgtgacc accgcaacgc cctccggctt
    19801 ccagcccgcc gccgccccgc agccccgcct cacgcgcgcc gacggatcgc ccatccgggt
    19861 gctcgtcgtc gacgacgagg cgtccctcac cgacctgctc cagatggcgc tgcgctacga
    19921 gggctggcag atccgcacgg ccgagaacgg gcaccaggcg ctcgccgccg cgcgcgagtt
    19981 caagcccgac gccgtggtgc tcgacatcat gctgcccgac ctcgacggcc tccaggtgct
    20041 gtcgcggctg cgcgccgacg ccgaggacat ccccgtgctc ttcctcaccg cgaaggactc
    20101 gctcgacgac cgcctcgccg gcctcaccgc gggtggcgac gactacgtga cgaagccgtt
    20161 cagcctggag gaggtcgtcg cccggctgcg cggcctcatc cgccgctcga cccttgtggt
    20221 gagcgacagc gtcgatccgg tgatccgcgt cggcgacctc acgctcgacg aggacagcca
    20281 cgaggtcgcc cgcgccggcg acccgatcga gctcaccgcc accgagttcg agctgctgcg
    20341 ctacctcatg cgcaacccgc gccgcgtgct gagcaagctg cagatcctcg accgggtgtg
    20401 gagctacgac ttcggcggca agtcgagcgt ggtcgagatc tacatctcct acctgcggcg
    20461 caagatcgac gccgggcgga acccgatgat ccacacggtg cgcggcagcg gctacatgct
    20521 caaggccgcg gagtgaccca gccgcaggcc gccacgccgc cgggcacgac gccgctgcgc
    20581 gccacaccgc tgcgggcccg gctcaccgcc gccgcgcgcg gcatgaccct gcggcgccgc
    20641 ctcgtgctca gcgtggtggg gctgctggcg ctcgcgagca tcctcatcgg cacggtgagc
    20701 atcctcgcgc tgcgggcgtc gctcgtgcag gaggtcgacc agcagctgca ggccaccgcg
    20761 gcgcgctcct cgaacctcat cgaccgggac gcggatcagt acggcagctt ccccggcgcc
    20821 cctcccggcg ggctcggcgc gttcgggcag caggtcggca cgatcagcgc gaccatcgtc
    20881 gacggcgtgg tctcgggcgg ctacatcgcc gaccgcgatg cggcagaggg cgagccgggc
    20941 ggcgcgggcg cggtggagct gacgcaggtg cagagccagc agctgcagag cgtgcccacc
    21001 gacgggatcc cccgcacggt cgacctcggc ggcgcgctcg gccgctatcg gctcgtcggt
    21061 gacaccgcgg ccaccggcgc gaccctcgtc accggcctgc cgatgaagcc cgccgacgac
    21121 gtggtcgagc agctcatcgt cgtgatctcc gtggtcgccg ccctcaccct ggcgctcgcc
    21181 gcggtgctgg gcgccgtcat cgtgcggcgc gcgctgcgtc cgctcgaccg ggtcgtcgac
    21241 acggccacgc acgtggccgc gctcgagctg gatcgcggcg acgtcgcgct cgaggcccgc
    21301 gtgcccgcat ccgacaccga cgagcgcacc gaggtcggcc gcgtgggcgc cgcgctcaac
    21361 ggcctgctcg ggcacgtcgc cgcggcgctg tcgtcgcggc aggcgagcga ggcgaaggtg
    21421 cggcgcttcg tgtcggacgc gagccacgag ctgcgcaccc cgctcgcctc catccgcgga
    21481 tacgccgagc tcacccgccg gggtccccac cagctgcccg aggacgtgac gcactcgctg
    21541 tcgcgcatcg agtcggagtc ggtgcgcatg accacgatcg tcgaggacct cctcctcctc
    21601 gcgcgcctcg acgaggggcg cgagctggag tcggatccgg tcgacgtcac gcgcatcctc
    21661 ctcgacacgg tcggcgacgc gagcgcggcg ggtccggatc atgactggga cctcgacctg
    21721 ccggacgact ccgtgagcgt ccccggcgac gacgcgcggc tccgccaggt ggtcgtcaac
    21781 ctgctcgcga acgcccgcac gcacaccccg gccggcacgc gcgtggtcgc gtcgctcgcg
    21841 gtggagggcg ccgggccgga tgcgcacgcc gtcatccgcg tgaccgacga cggccccggc
    21901 atcccgcctg agctgcaggc ctcgctgttc gagcgcttcg tgcgcggcga cggatcccgg
    21961 gcgcgctcca ccggcggcac gggcctcggc ctcgcgatcg cgcaggccat cgtgtcggcg
    22021 caccacggcg cggtgtgggt ggagtcggag ccggggcgca ccgtgttcgg ggtgcggctg
    22081 ccggtggcgc ggcgcgcggt ggatgcgcgc tccgagtcgg gcgcgcccgc gggatccgcg
    22141 tccgatcgct gggcgccgcc gtcgggcgca cccgtcgcgg atcgtccggg gccggtcggc
    22201 ggcagctgac atggatcccg tccgccgcct catgttctgg ctgcgcgtgc cgttcgtcgc
    22261 ggacgtggcg ctcgtcgtca tcggggtcgc
//
