LOCUS       NZ_CP073683            20237 bp    DNA     circular CON 15-MAY-2024
DEFINITION  Paenibacillus sp. S25 chromosome, complete genome.
ACCESSION   NZ_CP073683
VERSION     NZ_CP073683.1
KEYWORDS    RefSeq.
SOURCE      Paenibacillus sp. S25
  ORGANISM  Paenibacillus sp. S25
            Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae;
            Paenibacillus.
REFERENCE   1  (bases 1 to 5958851)
  AUTHORS   Li,T., Mann,R., Kaur,J., Spangenberg,G. and Sawbridge,T.
  TITLE     Transcriptomics differentiate two novel bioactive strains of
            Paenibacillus sp. isolated from the perennial ryegrass seed
            microbiome
  JOURNAL   Sci Rep 11 (1), 15545 (2021)
   PUBMED   34330961
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5958851)
  AUTHORS   Li,T.
  TITLE     Direct Submission
  JOURNAL   Submitted (20-APR-2021) Agriculture Victoria Research, AgriBio, 5
            Ring Road, Bundoora, VIC 3083, Australia
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 31-MAR-2020
            Assembly Method                   :: Unicycler v. 0.4.8
            Assembly Name                     :: AVR_PaeniS25_1.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 200.0x
            Sequencing Technology :: Illumina NovaSeq; Oxford Nanopore MinION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_019454085.1-RS_2024_05_15
            Annotation Date                   :: 05/15/2024 03:29:11
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,267
            CDSs (total)                      :: 5,136
            Genes (coding)                    :: 5,079
            CDSs (with protein)               :: 5,079
            Genes (RNA)                       :: 131
            rRNAs                             :: 12, 12, 12 (5S, 16S, 23S)
            complete rRNAs                    :: 12, 12, 12 (5S, 16S, 23S)
            tRNAs                             :: 91
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 57
            CDSs (without protein)            :: 57
            Pseudo Genes (ambiguous residues) :: 0 of 57
            Pseudo Genes (frameshifted)       :: 21 of 57
            Pseudo Genes (incomplete)         :: 38 of 57
            Pseudo Genes (internal stop)      :: 14 of 57
            Pseudo Genes (multiple problems)  :: 14 of 57
            CRISPR Arrays                     :: 4
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 06:16:07
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1158824
            Orig. end                         :: 1179061
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP073683.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from AgriBio, 5 Ring Road,
            Bundoora, Victoria 3083, Australia.
            Annotated using prokka 1.14.6 from
            https://github.com/tseemann/prokka.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..20237
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="proteusin"
                     /region_number="4"
                     /rules="(PoyD or TIGR03793)"
                     /tool="antismash"
     cand_cluster    1..20237
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PoyD or TIGR03793)"
                     /kind="single"
                     /product="proteusin"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20237
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:10237](-)"
                     /cutoff="20000"
                     /detection_rule="(PoyD or TIGR03793)"
                     /neighbourhood="10000"
                     /product="proteusin"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..10237)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PoyD or TIGR03793)"
                     /neighbourhood="10000"
                     /product="proteusin"
                     /protocluster_number="1"
     misc_feature    complement(184..197)
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: strong, score:
                     17.55"
                     /tool="antismash"
     misc_feature    complement(867..878)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: strong, score: 18.98"
                     /tool="antismash"
     gene            1083..1262
                     /locus_tag="KAI37_RS05120"
                     /old_locus_tag="KAI37_01040"
     CDS             1083..1262
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013369715.1"
                     /locus_tag="KAI37_RS05120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KAI37_01040"
                     /product="aspartyl-phosphate phosphatase Spo0E family
                     protein"
                     /protein_id="WP_023987319.1"
                     /transl_table=11
                     /translation="MIRDDILRQQLENARQKLYILQAKHGFNHASVLRQSVIMDNLINQ
                     YNHLFYIKEKKPTA"
     misc_feature    1113..1131
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 22.78"
                     /tool="antismash"
     gene            complement(1379..2281)
                     /locus_tag="KAI37_RS05125"
                     /old_locus_tag="KAI37_01041"
     CDS             complement(1379..2281)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1166: transporter,
                     EamA family"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019686326.1"
                     /locus_tag="KAI37_RS05125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KAI37_01041"
                     /product="EamA family transporter"
                     /protein_id="WP_071639784.1"
                     /transl_table=11
                     /translation="MNKVIAHYSESSRIYYGSTILALLIWSTSFIATKAAYTTFPPLTL
                     GLSRFIIASVVLGIVLLIKKEHIKVKPKDLVTISFSGVLGITLYFSMENIGVSLTTASN
                     AALIVASYPAITSLLELILYKVKISKYKICGIALAMIGVYFLTSVGESSDSKNQLIGNL
                     ILIGTGFAWAFYTFMTRKVVDKYPPVTLSFYQTVAGSIFFIPLALLEKDRWQAPTTGSF
                     MLLVYLGVFCSVIAFLLYNYGLIKLSPSSSVSLMNLVPIFGVLFSVLLLQETITWRQII
                     GGLVVIIGVLLSAHQTNRT"
     gene            2437..3297
                     /locus_tag="KAI37_RS05130"
                     /old_locus_tag="KAI37_01042"
     CDS             2437..3297
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013369717.1"
                     /locus_tag="KAI37_RS05130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KAI37_01042"
                     /product="TrmB family transcriptional regulator"
                     /protein_id="WP_071639785.1"
                     /transl_table=11
                     /translation="MKPKPNILEILRDLNFTEYEAKAYVTLLESSPLSGYAVSLNSGVP
                     RSKIYEVLSGMVNRGDIMVSQENTPLYVPLPPHELIAQRKRKAEQIFNVAQESLEQYTA
                     SFQNRENIWNISGYEAIINRINEGVKGAKHRILLEIWKEDAEVFRDALEQVAQQGIEVI
                     IVAYGELNFDFATVYRHDMSEEITSEIGGRWIVLSVDDREVVAGILSLGDDSRAAWTLH
                     PGLVMPITEVIIHDIYIMEILYEFREQLEAKFGPNLIHLRNKFAMGPNGKGYYIPLTEK
                     SMKRV"
     gene            complement(3384..5006)
                     /locus_tag="KAI37_RS05135"
                     /old_locus_tag="KAI37_01043"
     CDS             complement(3384..5006)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007429103.1"
                     /locus_tag="KAI37_RS05135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KAI37_01043"
                     /product="DUF1593 domain-containing protein"
                     /protein_id="WP_104496567.1"
                     /transl_table=11
                     /translation="MRERKGLNIFLLAMICILIISGCSGKAPAVVKDESAAPTEKQTEN
                     KAENKATKARTVITTDGEVDDMNSVIRFLLYSNEMDLSGIVLTSSVYHYAGDEKAGIKP
                     FRWTGTQWVTDMIDAYGEIYPNLIKHAEGYPKPEYIKSVTKIGNISNKGEMDKETEGSN
                     FLKTLFLDDDKRDLYVQTWGGTNTTARALKSIEDEYKNTDQWETIRKKVSDKLVLYIIL
                     DQDDSYNNYIAKNWPDIRIINDQSNFWHFAYAWKMHTEEVNSKLHGEWNFKNIKDGHGK
                     LLNMYALMGDGNIIKGELDEEQRGSEAYLKKNPQYDKYDFISEGDSPSFFYLIDNGLRS
                     MENPTYGGWGGRFGVVNDKLFRNTVLDYDVHTKKFEAEYSLMRWFDDVQNDFAARADWA
                     IASDYKDANHNPTLTIKEGLDLTASPGEKITLHAEGSDPDGNQLTYKWWRYFEADTYED
                     SKVKPAQVKPELLGDMQLGLHREVAKGEKVNTIDLQGSDTNAVSFTVPADAKSGNTLHI
                     IAEVQDNGKHPLKHYQRVIVTVK"
     gene            complement(5242..6324)
                     /locus_tag="KAI37_RS05140"
                     /old_locus_tag="KAI37_01044"
     CDS             complement(5242..6324)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_process="GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /GO_process="GO:0046417 - chorismate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013369718.1"
                     /locus_tag="KAI37_RS05140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KAI37_01044"
                     /product="bifunctional 3-deoxy-7-phosphoheptulonate
                     synthase/chorismate mutase"
                     /protein_id="WP_013309063.1"
                     /transl_table=11
                     /translation="MSTNENSLELLREQLDATNLQLLELLSQRAELAGQLGKLKEAQGV
                     PDFDPVREQQMLDKLIAANRGPFDDATIRQLFKNIFKASLNYQKEEHKKHLIVSRKNQP
                     DSTVIKVKDTLVGGKASIMVAGPCSVESYQQTREVGAALKEAGVPILRGGAFKPRTSPY
                     DFQGLGVEGLQILKRVGDEFGLATISEIVDPRHLEEAIQYIDIIQIGARNMHNFELLKA
                     AGETRTPVLLKRGLAATMEEFLHAAEYIVSRGNTQVMLIERGIRTYEKWTRNTLDISAV
                     PILKKESHLPVLVDVTHSTGRKDILAPCAKAALAAGADGIMVEVHPNPAVALSDAQQQL
                     NIPEFHNFLSEVKESGLFKA"
     misc_binding    complement(6412..6683)
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
     misc_feature    complement(7113..7124)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 18.53"
                     /tool="antismash"
     gene            complement(7148..7408)
                     /locus_tag="KAI37_RS05145"
                     /old_locus_tag="KAI37_01046"
     CDS             complement(7148..7408)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013369720.1"
                     /locus_tag="KAI37_RS05145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KAI37_01046"
                     /product="hypothetical protein"
                     /protein_id="WP_025723196.1"
                     /transl_table=11
                     /translation="MANRDDRTTELHDNDFEPSLQNAETNWENLTEGPDTPLEDVPDAD
                     ELTPNSPVDPSAPAEFLHGTDLLNGTDGDEEEQLDSDDMLD"
     gene            7592..7879
                     /locus_tag="KAI37_RS05150"
                     /old_locus_tag="KAI37_01047"
     CDS             7592..7879
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013369721.1"
                     /locus_tag="KAI37_RS05150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KAI37_01047"
                     /product="hypothetical protein"
                     /protein_id="WP_023987328.1"
                     /transl_table=11
                     /translation="MEWYMFGPMISRIRVGQKASTPGFSRTLIRRPEGLYWTDGGQAGK
                     IVEIRDYLFSDIWTIYEDEDCEPWLGLREQKERREQEMIINQYEDFTKNE"
     gene            8012..9901
                     /locus_tag="KAI37_RS05155"
                     /old_locus_tag="KAI37_01048"
     CDS             8012..9901
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019686330.1"
                     /locus_tag="KAI37_RS05155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KAI37_01048"
                     /product="sensor histidine kinase"
                     /protein_id="WP_076293425.1"
                     /transl_table=11
                     /translation="MRHVPKAVATLLAVIVLLLSLGHSTYAAKMTPERDYKIPSWDMRW
                     GAVNEDGSLDEVKDPSKIWMHIEDDTQLLRQPGNIGSAWIRIKLPSLNDETPAVLFENI
                     YGRHITLYKDGTNFYESYRGYNYENNRILIPLKPEDSGKTLYIWTESSKNRLGIIGNVM
                     TGDYRDLLGTLVRMDVLDIVLGSTFIFIALVLLICSFFLFRPSMAMWLSLSAIVLSIGL
                     MIVTYSPFLYTFYRGYGKLYLQLFDVALFILLPSLAYFFEQNINSIILIRKFRKLLTAY
                     SLFCFTMMIVNLGAQERLNDIYYFFSVVILGILLVALMILLVFASVRMALKGDHEAIIL
                     STGFAFFAVISIGELSWFFILDGHYNMFLWKWGVFGFVLALIAILGRRLAEKHKQVVRY
                     SRELEMFNNELQRSEKMEIISDLAASVAHEVRNPLQVTRGFLQLMSKQEDGKNKDYLHI
                     ALEELDRASAIITDFLTFAKPEFDQTKTLTILDEFKHIEGIISPMANLQGGKISLDIPQ
                     EIKVRGNSSKFKQAFINIIKNSIEALRDQGHIHIWAYVDNGEAVIHIRDNGEGMDAQTL
                     SRLGEPYFSNKTKGTGLGMMVTFRIIETMNGKITFTSAKGVGTEATIRFPVAG"
     gene            complement(10001..10237)
                     /locus_tag="KAI37_RS05160"
                     /old_locus_tag="KAI37_01049"
     CDS             complement(10001..10237)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     proteusin: TIGR03793"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007429107.1"
                     /locus_tag="KAI37_RS05160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KAI37_01049"
                     /product="NHLP leader peptide family RiPP precursor"
                     /protein_id="WP_013309068.1"
                     /sec_met_domain="TIGR03793 (E-value: 8.8e-19, bitscore:
                     65.3, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MATEVLQTQVIQKAWEDASFREKLMTDPKSAIRDVLGVVIPDHIQ
                     IKTLEETPDQFFLVIPPDPSGVLAASQKPRSMW"
     gene            complement(10313..11248)
                     /locus_tag="KAI37_RS05165"
                     /old_locus_tag="KAI37_01050"
     CDS             complement(10313..11248)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007429108.1"
                     /locus_tag="KAI37_RS05165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KAI37_01050"
                     /product="hypothetical protein"
                     /protein_id="WP_220030847.1"
                     /transl_table=11
                     /translation="MEWYFAYKNELENVFRQAEERTSTFPAPFQQEGLDYLARFNPLRE
                     DSTRNYICYLLPFWLQELTELPPETCRKLSLGNVFVMAHYLIQDDVMDTAADNRKTQLA
                     LSQLFYTECLSVYRDLFPATSPFWSYARAYVDEWAVSVTSEGTEDYFQGERNKVALKAS
                     PLKMAGTGALLLAGRADLIQIITDMTDLALLVLQMSDDWADWSEDLVEHSYNCLLSHIS
                     AEQKTAYCEGLGPKQIQEAIYVRGALASYVNIADQAVQQLETLEPSIHGLRSFAHSITA
                     ELGEVAAEIEGGRSHLRRGGLDYWLSKNMK"
     misc_feature    11320..11332
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 21.58"
                     /tool="antismash"
     misc_feature    complement(11343..11357)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 22.42"
                     /tool="antismash"
     misc_feature    complement(11411..11424)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.42"
                     /tool="antismash"
     gene            complement(11424..12497)
                     /locus_tag="KAI37_RS05170"
                     /old_locus_tag="KAI37_01051"
     CDS             complement(11424..12497)
                     /GO_function="GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1235: polysaccharide deacetylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013369725.1"
                     /locus_tag="KAI37_RS05170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KAI37_01051"
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="WP_220030848.1"
                     /transl_table=11
                     /translation="MFIAKAGKWTAIMSITLSLFTGSLVISSNQAHAADCSNGYVALTF
                     DDGPNPSNTKALLSALKQNGLRATLFNLGQNAQNNSSLVRQQQAAGMWIGNHSWSHPHM
                     TQLSTSQMSSEITRTQQTIQSITGTAPKLFRPPYGETNATLKSIETQNGLTEVLWNVDS
                     QDWNGASTAQIVAAAGNLKNGDVMLMHDQYQTTLQAIPQIAQNLKNRNLCSGMISPSNG
                     RAVAPDGGDGETPPNKGTKVEAENMTKGGQYTSNISSPFNGVALYSNNDSVKFTQNFTS
                     GTHSFSLRGASNNSNMAKVDLKIGGQTKGTFYFGGSSPAVYTLNNVSHGTGNQEIELVV
                     TADDGTWDAYIDYLEII"
     gene            complement(12535..13623)
                     /locus_tag="KAI37_RS05175"
                     /old_locus_tag="KAI37_01052"
     CDS             complement(12535..13623)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010347573.1"
                     /locus_tag="KAI37_RS05175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KAI37_01052"
                     /product="glycoside hydrolase family 11 protein"
                     /protein_id="WP_220030849.1"
                     /transl_table=11
                     /translation="MKQKRIRLFLSILICFSLILPAVNAQAATTITSNQTGTHDNYYYE
                     LWKDHGNTSMTLNNGGAFSAQWSNIGNALFRKGKKFDETKTHQQIGNISVNYNADYQPN
                     GNSYLCVYGWAVDPLVEYYIVDSWGSWRPPGATSKGTFNVDGGTYDIYETTRVDQPSIK
                     GDKTTFQQYWSVRTSKRTSGTISVSEHFKKWESMGMKVGKLYETSLTVEGYQSSGSANV
                     TSNTVTIGGNSGGGTETPPGTSTKIVAQSMTKGGQYTSNISSPFNGVALYANNDSVKFT
                     QNFTSGTHSFSLRGASNNSNMAKVDLKIGGQTKGTFYFGGSNPAVYTLNNVSHGTGNQE
                     IELVVTADDGTWDAYVDYLEIN"
     gene            14000..14476
                     /locus_tag="KAI37_RS05180"
                     /old_locus_tag="KAI37_01053"
     CDS             14000..14476
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016821363.1"
                     /locus_tag="KAI37_RS05180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KAI37_01053"
                     /product="hypothetical protein"
                     /protein_id="WP_071639792.1"
                     /transl_table=11
                     /translation="MKKQWKLITATLYGGVMMYGSAGMIEAAGIKTSPQMQALTPSNSI
                     QGEADPGRMQSQDCHRQGHAYKHGHGKRPGGWDHHLNEKVAKLLGITPVRLENELGQGK
                     SLSDIAKSKGINEEQLINKLKNEMTVDLKRLVNRKGPITFDRKSGTSNEAQLKR"
     gene            complement(14564..15058)
                     /locus_tag="KAI37_RS05185"
                     /old_locus_tag="KAI37_01054"
     CDS             complement(14564..15058)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013369727.1"
                     /locus_tag="KAI37_RS05185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KAI37_01054"
                     /product="hypothetical protein"
                     /protein_id="WP_071639793.1"
                     /transl_table=11
                     /translation="MNDKLKGLLVGLTIGTMITGATAMAASGTSVNAVVKKFDVFLEGT
                     KKNTAEALIYNGNTYISVKDIGIAEGRQISLIDNKLYLGKQQNIITENQAINILFDKIK
                     NEAVKYNLNVMVEGLEGTKYSLRAYEDFPDHIATYGFYYVDKYTGKVTKYDIVHDKEVA
                     I"
     gene            complement(15153..15659)
                     /locus_tag="KAI37_RS05190"
                     /old_locus_tag="KAI37_01055"
     CDS             complement(15153..15659)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016821362.1"
                     /locus_tag="KAI37_RS05190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KAI37_01055"
                     /product="DJ-1/PfpI family protein"
                     /protein_id="WP_071639794.1"
                     /transl_table=11
                     /translation="MKSHVLIYDGYVSFEIMLATYFMKTKGDIVTIGVTKDPVISYEDF
                     KVMPSVAIDEVSAEDIQLLIIPGGDNTQLKTNKQLLALINTLNNDNKVIATICSATELL
                     EIAGVSYKSPVNHPTGLEIHKNIIAAKPNKYVDFAIEIGKVMNIYTDDEDLRETIDFFK
                     LFKDS"
     gene            complement(15867..16274)
                     /locus_tag="KAI37_RS05195"
                     /old_locus_tag="KAI37_01056"
                     /pseudo=""
     CDS             complement(15867..16274)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016819375.1"
                     /locus_tag="KAI37_RS05195"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="KAI37_01056"
                     /product="AbrB/MazE/SpoVT family DNA-binding
                     domain-containing protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MKNTGMTRPLDTLGRIVIPKEMRTSMGIQAGESLEFYLDCETGLL
                     SMRKYIGVCCHLCYSIQDLSYFRDSFLCKKCINDLKGNIGVS"
     gene            16473..17870
                     /locus_tag="KAI37_RS05200"
                     /old_locus_tag="KAI37_01057"
     CDS             16473..17870
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016821361.1"
                     /locus_tag="KAI37_RS05200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KAI37_01057"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_220030850.1"
                     /transl_table=11
                     /translation="MEITPTIQAEIQTYLKRKGLTMTKFGHTIDLNVGTVSSIVTGNRS
                     ISVHQLDSITAGMNLPPDYFYERYIEECLEESPLNWKKISPFLYRCIELGRLDCLQRVV
                     ILLLDNPNYLPSLFEVAENVYKDGYNEAAAYLYKKVAESEKQQHSERLAICQYRLFQIN
                     IGQDRAVNLQAAIEFAPFVDRLDEIEQLDALKDLANVYRSLSMWDKVYEFSSQMGQMGK
                     IQYNLVNNSKRKGTEPRKKLSRPLFVYIVYSELLCANACDAKGDHEQALEHIRGYADLS
                     WVKEKDPDSLYWKKQYQQWAKINTYVNRLMSGDISVLPDYVEHMAAENEIFSELLNVLE
                     VANRYNVDVDHILKRFESQIAAYQEPLSSDMYTQQVLPEEYVRFWYKMAKYSLYKGRYP
                     YGFKCLINAFEKAVTINHVLLIANCFGLFFHFKTHAAPETQTQFQSIYEEVWEKNDQKD
                     GFLLGGN"
     misc_feature    complement(18066..18080)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 23.68"
                     /tool="antismash"
     gene            18097..18282
                     /locus_tag="KAI37_RS05205"
                     /old_locus_tag="KAI37_01059"
     CDS             18097..18282
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014280170.1"
                     /locus_tag="KAI37_RS05205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KAI37_01059"
                     /product="aspartyl-phosphate phosphatase Spo0E family
                     protein"
                     /protein_id="WP_076293429.1"
                     /transl_table=11
                     /translation="MSRYETVPLIQQMEHARQQLHDLYEEYGFGHACVLQQSMLLDELI
                     NQYNRMFQTKKLPHYV"
     gene            complement(18551..19777)
                     /locus_tag="KAI37_RS05210"
                     /old_locus_tag="KAI37_01060"
     CDS             complement(18551..19777)
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1088: acyltransferase 3"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013309078.1"
                     /locus_tag="KAI37_RS05210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KAI37_01060"
                     /product="acyltransferase"
                     /protein_id="WP_071639797.1"
                     /transl_table=11
                     /translation="MSKPRIAEWTELRGLAYLAVVLQHCIGEYIYRSDIQQPDSVMLAM
                     LYHLTRFGTPTFVFLSAALLFYNGNKPIGYPRYIGRRFRDIYVPFLCWTVIYWVCTQNW
                     STAQWGNIYFYKGMFEEMIIPVSGYHLWFVVMIFQFYILFPLFSKAAGQVQAFLRRYST
                     KRRKQLVLAIMLIAAAVYALLLQWSYYDMSAWSTRLPSFWQTLLDYRTYNFVMYFFYFM
                     LGAVCAYMTDTWRGLAKQTLPWNVFVFIGLFMLMGHTMLIQSGDTINLNISTYLKPSTF
                     VLIVSQLLLLYGLLLHLQKDTRSEPFRRMLNWIGRYSFGGYLAHALVLAFISYYTRPLA
                     LGDHHFTATLITFIVVASVSLGISWLFAHLPGGNWIVGSKGRQRLNWHSFRFQFLSSKR
                     ASKSTQELG"
ORIGIN
        1 tgttcgtagg agtacggttg tttcaaggcc ttctatccgg gtttattcct gctgcgattg
       61 cgctggtcgg aacgggttcg cctgaggaga aaaccggcta tgcactcggt attatggcga
      121 ccgctggggc gacaggcagc attataggtc cgttgattgg cggtgtagtg agccattatt
      181 atggcaatcg gaatgccttt tttttctctg cagctcttgt gctggtatct gcgttaatcg
      241 cgacttttgg cgctagagag gacagcttca agggaaccag tacccgctcg catgttcgtg
      301 atgatatcaa ggaggctatt gctaatcggc ctttgtgctt tttgcttatt ctggcgggat
      361 taagtacctt ttccgtcatg atactagaac cgttaattac ggtatatgtg cttgaaatgg
      421 gagttgaccg tagccgggcg tctttaagtt ccgggattgt attctcagcc gtaggtattg
      481 cggcggtgct catggctccc caatggggac ggattggggg acggaccgga ttcgcacacg
      541 tgctgctgat tgggctgatc ggttcgggaa tcgggaacat cttacaattt tttgtaacca
      601 actttgttgg ttttggtgcg cttcggtttg gatatggatt gttttatgcg tccgtcatgc
      661 cggctatcaa cgcaatgact gtggaggtta ccaagccgga gtttcgcgga cgagccttta
      721 gcctgagcca atcagccact caactcgcga caatggcggg gccgttgatt ggcggtatgc
      781 ttggcagctg gatgccaatc cgttggatct ttgtgttaaa cggtggcata ctgctgcttg
      841 cagcgttgtt gctatgggcg aagggaaaaa acgttttccc ggtttcagtc aagaagaacg
      901 taacggatca ggatattcat tctgccggat aggcgaatga cactggattg tctaacggca
      961 taagcttaag gctcatagag caggtctttt tttgtgttat tagataatta tcccaaacct
     1021 ttacttttag tatacttatt cataaccctc tacactgata atatgacaag gagggatata
     1081 ttatgataag agacgacatt ttgcgtcaac agcttgagaa tgctcgtcaa aagctgtata
     1141 ttttgcaagc aaaacatggc tttaatcatg ccagtgtgct cagacagtct gtaattatgg
     1201 ataacctcat caatcaatat aaccaccttt tttatataaa agaaaaaaag ccgactgcat
     1261 aaatgcaacc gactgggcga gaaacttttg gtgaggtcac tcgcccttgt actgtagcgc
     1321 tatacctata acaacgatgc ttatcttaac ttttataact attgtgcaat ctatcatttt
     1381 aggtacggtt cgtttgatga gcactcagta ggacgcctat aatgacgacc aaaccaccaa
     1441 tgatttggcg ccatgtaatc gtttcttgca aaagcaacac agaaaataag actccaaata
     1501 tcggaaccaa attcatcaga gaaacggaac tgctcggtga cagcttgatt aatccgtaat
     1561 tgtaaagcaa aaatgcgata acggagcaga atacgcccag atatactaac aacataaacg
     1621 atcctgttgt cggagcctgc caacgatcct tttctaatag agccaacggt ataaaaaaga
     1681 tacttcctgc aacagtttga taaaaagata acgtcacagg cggatatttg tctactacct
     1741 tgcgcgtcat gaaagtgtaa aacgcccacg caaaacccgt tccaatcaat attaaatttc
     1801 cgatgagttg attcttacta tcagaacttt cgccaactga agtcaagaaa tataccccga
     1861 tcatagccag tgctatgccg caaattttat atttggatat tttcacttta tacaaaataa
     1921 gttcaagcag cgatgtaatt gcgggatatg atgcaacaat taatgctgcg ttggaagcgg
     1981 tagtcaaact aacccctata ttctccattg aaaaatagag agtgattccc aaaacaccac
     2041 taaacgaaat cgtaaccaaa tcttttggct ttactttgat atgttctttt ttaatcagca
     2101 aaacgatacc tagcacaacg gaagctataa taaatctgga tagacccaag gtaagagggg
     2161 ggaacgtcgt gtaggctgct ttggtggcaa taaacgatgt actccagatc aatagggcca
     2221 gaatcgtaga accatagtaa atccggctgc tttcgctgta atgagctatg actttgttca
     2281 agttaaatcc tccctgaggt aatcccctgt gaaatgatga tagtagctac taaagtgact
     2341 actataaaaa cgttactaaa aagatagtgt gtatatcagt ttttgtcaag gggaagtgat
     2401 atagtaagga tgaacacgaa ttgaggagaa gacgtcatga aaccaaaacc aaatatatta
     2461 gaaattctac gggatttgaa ttttacagaa tatgaagcca aggcttatgt gaccttattg
     2521 gaaagctctc cactttcggg atacgccgtt tcattgaatt ccggggtacc gagatccaaa
     2581 atttacgagg ttttgtctgg aatggtcaac cgtggggata tcatggtcag tcaagaaaat
     2641 acgcctctgt atgtgccgct cccgccacat gaattgattg ctcagagaaa acgcaaagca
     2701 gagcagattt tcaatgtggc gcaagagagt ttggaacagt acacagcatc atttcaaaat
     2761 agagagaaca tttggaatat ttcggggtat gaagccatta tcaatcgcat aaatgaaggg
     2821 gtaaagggag caaaacaccg gattttattg gaaatttgga aagaggatgc cgaggtgttc
     2881 cgagatgcct tagagcaagt cgctcaacaa ggaattgaag tgatcattgt agcgtatggg
     2941 gagcttaact ttgatttcgc tactgtttac cgccatgata tgagtgagga gattacgtct
     3001 gaaattggtg gtcggtggat tgtacttagc gtagacgacc gtgaggtcgt agctggcata
     3061 ctttcacttg gtgatgacag ccgcgctgca tggacgttac atccgggtct ggtgatgccg
     3121 attacagaag taattattca tgatatttat atcatggaaa tcctatatga gttccgtgaa
     3181 caattagagg cgaaatttgg ccctaatcta attcatcttc gcaataaatt tgctatgggt
     3241 ccgaatggca aaggatatta tattcctttg actgaaaaaa gcatgaaacg tgtatagaga
     3301 ttgtccgagg tgcgatgtac aacaataaaa aggctcatgg agtgttattc catgagccta
     3361 attttagtgg atgttgtgtt ctattatttt acggttacaa tcacacgctg ataatgcttt
     3421 aaaggatgtt ttccattgtc ctgtacttct gcaatgatat gaagcgtatt ccctgactta
     3481 gcatctgcag gaactgtgaa actaactgca ttcgtatcac taccttgcaa gtcaatcgtg
     3541 tttactttct cgcctttagc tacttctcga tgaagcccaa gctgcatatc ccccagtaat
     3601 tcaggtttaa cttgtgctgg ttttacttta gaatcctcat acgtgtctgc ttcaaaatat
     3661 ctccaccatt tataggtcaa ttgattaccg tcgggatctg aaccttctgc atgcagggtt
     3721 attttctccc ctggactagc ggttaggtct aatccttctt taatagtcaa cgttggatta
     3781 tggttggcat ctttgtagtc ggatgcaata gcccaatctg cacgagcagc aaagtcattt
     3841 tgaacatcat caaaccaacg catcagagaa tattctgctt cgaatttttt cgtatgcaca
     3901 tcataatcta acacggtatt tctaaataat ttatcgttaa cgacaccgaa acgacctccc
     3961 cagccaccat aggttgggtt ttccatactc cgcaatccgt tatcaattaa atagaagaag
     4021 gatggagaat caccttcaga aataaagtca tacttgtcgt attgtggatt tttctttaag
     4081 taggcctcac tgcctctttg ttcttcatcc aactcgcctt tgatgatatt gccatcgccc
     4141 atcaaggcat acatattgag caacttgcca tgaccatctt taatattttt gaagttccat
     4201 tccccgtgca acttgctgtt tacttcttct gtgtgcattt tccaagcata agcgaaatgc
     4261 cagaagttag attgatcatt aataattctg atgtcaggcc aatttttagc gatgtaatta
     4321 ttgtagctat cgtcctggtc cagaatgatg tacagtacga gtttatcact tacttttttt
     4381 cgaatcgttt cccattgatc tgtattttta tattcgtctt caatggactt tagagctctg
     4441 gccgtggtat tggttccacc ccaagtttgt acgtacaaat ctcttttgtc atcgtccagg
     4501 aaaagtgttt taaggaaatt ggagccttcc gtttctttgt ccatttcacc tttatttgaa
     4561 atgttaccta ttttggtaac gctcttgatg tattcaggct ttggatatcc ctcggcatgt
     4621 ttgattaagt tgggataaat ctctccgtag gcatcaatca tgtccgttac ccattgtgtt
     4681 ccggtccatc taaatggctt gatgccagcc ttttcatcac ctgcataatg atatacggag
     4741 ctagtcagta caatcccgga caaatccatt tcattggagt aaagaagaaa gcgaatgaca
     4801 gagttcatat catctacttc tccatcggta gtgatcaccg ttctggcctt ggtcgcttta
     4861 ttttctgctt tattttccgt ttgtttttct gttggagcag cgctttcatc tttcacaacg
     4921 gcgggcgcct taccactgca gccactgatg atcagaatac atatcatggc taatagaaaa
     4981 atgtttaacc cttttctttc tctcatttct gttcccctct ctgaacgttc ctatgatgtt
     5041 ttttaggatt ataaccatga aggtattctc tttattcaag aattaggcat aaaaaaaacc
     5101 taaatgtata tgtgtctcaa caaaagttga gcatatatac atttaggttt tgcctgcatg
     5161 atcagtcaca atcctgattc aattttacat cattgtccga gaaaatgaaa gcggtttatg
     5221 aatccgggca taaaattaat tttacgcttt gaataaaccg gattctttga cttcagacag
     5281 gaagttgtgg aactcaggaa tgttcagctg ttgctgagca tcagacaaag cgactgccgg
     5341 gttcggatgg acttccacca tgataccgtc agctccagca gccagggcag ctttggcgca
     5401 aggggccagg atgtccttac gtcctgtgga gtgagtcacg tccaccaata caggtagatg
     5461 gctttccttt ttcaaaatcg gaacagcgga aatatccagt gtgttacgcg tccatttttc
     5521 gtacgtacgg ataccgcgtt caatcagcat gacttgcgtg ttaccacggg aaacgatgta
     5581 ttcagcagca tgaaggaact cttccattgt ggcagccagt ccgcgtttga gcagaaccgg
     5641 agttctagtt tcacctgcag ctttgagcaa ttcaaagttg tgcatgttgc gcgcaccaat
     5701 ttgaataatg tcgatgtatt ggatcgcttc ctccaaatgt cttggatcga cgatttcact
     5761 gattgtagcc agcccgaact cgtcgcctac acgtttgaga atttgcagtc cttccacgcc
     5821 cagtccttgg aaatcgtacg gagaagtacg tggtttgaac gcgccaccac gaagaatcgg
     5881 cacaccggct tccttgagag ccgcacctac ttcacgagtt tgctggtagc tttccaccga
     5941 gcagggacct gcgaccatga tggaggcttt gccgcccacc agcgtatctt taaccttaat
     6001 aactgtgcta tctggttgat ttttgcggct gacgatcaga tgttttttgt gttcttcttt
     6061 ttgatagttc aaagaagcct tgaaaatatt tttgaacagc tggcgaatcg tagcatcgtc
     6121 aaaaggccca cggttagccg cgatcagctt gtccagcatt tgttgctcac gtaccggatc
     6181 aaagtcaggt accccttgag cttccttcaa ttttccaagt tgtcccgcca gttcagcgcg
     6241 ttgggacagc agctccagca attgcaaatt tgtagcatcg agctgttcac gcagcagctc
     6301 caaagaattt tcgtttgtag acatacagta cacccttccc gaatttaaat ttgttttttc
     6361 tgtcagttca taaacttttc ttgcagaaaa taacacaaaa aggcactcgt cgcaagggac
     6421 gaatgccgtg gtaccaccct aattacagaa gtatacatac gaatcgtcaa cgtcgttcag
     6481 tcgacggcag taacttctga gcttgatgcc cgtaacgggg gcttccggaa acctctactg
     6541 cggacaaagg aatgaatccg tctgtcggtt caaggctcga ctcgggagtg aatttcaacg
     6601 cgggattgcg gtacgctctc agcaattcgt acctttctgt gggaatccgt tagacgttta
     6661 cttgtctccg tcactgtctt tgttcatggt attcaaaaga tttgacctta ttttaaacaa
     6721 agtaggtgca gaaggcaagc cctgattatc aggttcaagt ttttgctctt gaattgctgc
     6781 ccttacaaca tgtgaagttc aaaagggtgc actcaagcca tgtgtatcat ctgtgtggct
     6841 tgggtagcac ccttttggca ttctctgtct gtcctttcat tttccttgat ccctgggttc
     6901 gggcttcgca gatgcgactc ctcgtggatt atcttcggcc gagatatcat ctgtagttgt
     6961 cttgtccgcg gtcctacgtt cgtctgcttc cacgggattc aaggttttgt agcgcttata
     7021 ctccatatcg gcctgagaca tcggatcttt atacatagga gatcagtcaa ctcctttctg
     7081 ttatacactt cattacccgc atagcagaat gggtaaccgt tttctttcac ccgataaaat
     7141 gaagtggtta atccagcata tcgtcgctgt ccagttgctc ttcttcgtcc ccatcggtac
     7201 cattcagcaa atcggtacca tgcaggaatt cagcaggagc agaaggatcg acaggactgt
     7261 tcggtgtcag ttcatcggca tcggggacgt cctccagagg agtatccggc ccttcagtaa
     7321 gattctccca gttggtttct gcattttgca gagaaggctc gaaatcattg tcatgtagct
     7381 cagtagttcg atcatcacga ttggccatgc tgctcagctc ctttactttt tgttgcttat
     7441 tccgacctta cccaaacaga agaacggcta aaccttgagt tagtgtgtct gtaggaagtt
     7501 aaaatcatgc gaatagggat atgcccattc tcaattagcg tttttttggt aactgctgtg
     7561 atatgataaa gaagataggg agggatatga attggaatgg tacatgtttg gtccgatgat
     7621 tagtcgtatc cgagtaggtc aaaaggcatc taccccggga ttttcccgca ccctcattcg
     7681 gcgcccagaa ggcttatact ggacagatgg cggacaagcc ggaaaaatag tagaaatacg
     7741 cgattattta ttttccgata tttggacgat ctatgaagat gaagattgtg aaccatggtt
     7801 ggggcttaga gagcagaagg agcggcgcga acaggaaatg atcattaatc aatatgaaga
     7861 ttttacaaaa aatgagtaaa aagaacatga tacccttctt atgaagaagg tatgcacatc
     7921 atcgtataga ataatataat ttcaggacgt aaaaaatgtt aaaacgtata caaacttgta
     7981 aatcctacta tgtaactttg aggtgcttaa catgaggcat gtgcccaaag ctgtcgccac
     8041 cctgctagcg gtcattgtgt tgctgttgtc gctgggccac tccacctatg cggccaaaat
     8101 gaccccggaa agggattata aaataccctc ctgggatatg agatggggag cggtaaacga
     8161 ggatggctct ttagatgagg taaaggaccc tagcaagatc tggatgcata ttgaagatga
     8221 tacacaactg cttaggcagc ccggcaatat aggctccgcc tggattcgta ttaagttacc
     8281 ttcgctaaat gacgaaacgc cagcggtact ttttgaaaat atttatggca ggcatattac
     8341 gctgtataaa gatgggacca atttttacga atcctaccgt gggtacaatt atgagaataa
     8401 tcgtattctg attccgctga agccggaaga cagcggtaaa acattataca tatggacgga
     8461 aagcagtaag aatagactgg gcattatcgg caatgtgatg accggtgatt atcgtgattt
     8521 attgggaacc ttggtcagaa tggatgtttt agatattgta ctgggcagta cgtttatctt
     8581 tatcgccctg gtactactga tctgctcgtt ttttctgttc cgtccgagta tggctatgtg
     8641 gttgtcccta agtgcgattg tattgtctat tggtctgatg atcgtaacgt attcaccatt
     8701 cttgtataca ttctatcgcg gctatggaaa gctgtactta caactttttg atgtggcact
     8761 atttattctg ctgccttcat tagcctactt ttttgagcaa aatatcaatt cgattatact
     8821 gattcgtaaa ttcagaaagt tgttaaccgc ctactctttg ttctgcttta ccatgatgat
     8881 tgtaaattta ggagcacagg agcggttgaa cgatatatat tattttttta gtgtagtgat
     8941 cttgggtata ttactcgtcg ccttaatgat attgctggta tttgcttcgg ttcgcatggc
     9001 acttaagggt gatcacgaag cgatcatttt atcgacaggc tttgcatttt ttgcagtcat
     9061 ctctatcggg gaactgagct ggttctttat tctggacgga cactacaata tgtttttgtg
     9121 gaaatggggc gtgttcggtt ttgtactggc gttgatcgcg attttgggca gaagactggc
     9181 agaaaagcac aagcaggtgg ttcggtattc cagagaactg gagatgttca ataatgagct
     9241 tcaacgttcg gagaaaatgg agattattag cgatctggct gcatctgtag ctcatgaggt
     9301 acgtaatccc cttcaggtta cacgtggatt tcttcagttg atgagcaagc aggaggatgg
     9361 taaaaacaaa gactatctac atatcgctct ggaggagctg gatcgagctt ccgcgattat
     9421 tactgatttt ctgacttttg ccaagccaga gtttgaccaa accaaaacgt tgaccatatt
     9481 ggatgaattc aaacatattg aaggaatcat cagtccaatg gctaatttac aaggtggaaa
     9541 aatttcactg gatattcccc aggaaatcaa agtacgcggg aattcttcca agttcaagca
     9601 ggcgttcatc aatatcatca aaaacagcat tgaagcgctg cgagaccagg gtcatattca
     9661 tatatgggct tatgtggaca acggagaagc tgtcattcat attcgggata atggtgaagg
     9721 gatggatgct cagactttat ccagactagg tgagccttat ttctcgaata agacaaaagg
     9781 cacgggtttg gggatgatgg tgacttttcg gattattgaa acgatgaatg gaaaaataac
     9841 ttttacaagt gcaaaagggg tgggaacgga agcgaccatc cgcttccccg tagccggata
     9901 atatccggct tttttgcatt cggagaaaac ggagggaagc ttgctgagcc cacccacatg
     9961 agattaagga gtatagatta aataagcatt aacaaccaat ttaccacatc gagcgaggtt
    10021 tctgggatgc agcgagtaca ccggaggggt ctggaggaat taccagaaaa aactgatcag
    10081 gcgtttcctc taacgttttg atttggatat gatcggggat cacgactcct aacacatcac
    10141 gaattgcaga tttgggatct gtcatcagtt tctctctgaa actggcatcc tcccaagctt
    10201 tttgaatgac ttgtgtttga agaacttcag tagccatcaa aaatcaccct ctcattcaat
    10261 tggttatatt tacctagtca gtataccacg aaagactcag aaaaatctag cattatttca
    10321 tatttttgga gagccagtaa tcaagtccgc ctcttcttaa atgcgagcgt ccgccttcaa
    10381 tttccgccgc cacttcgccc agttctgctg tgatagaatg tgcaaagcta cgtaggccgt
    10441 ggatagaagg ctccagggtc tctaactgtt ggactgcttg atcggcaatg ttcacatagc
    10501 tggcgagcgc accgcgtaca taaatcgctt cctgaatctg tttgggtccc aatccttcac
    10561 agtaagccgt cttctgctcg gcactgatat gggacaaaag acagttatag ctatgttcga
    10621 ccaaatcttc tgaccaatcc gcccaatcat ccgacatttg aagcacgagt agcgccaagt
    10681 ccgtcatatc tgtaatgatc tggatcagat cggcacggcc tgcaagcagt aaagcacccg
    10741 ttccagccat ttttaatgga cttgctttca gcgcgacctt atttctttct ccttgaaaat
    10801 agtcctctgt tccttcggat gttacactaa cggcccattc atcaacatac gctcgggcat
    10861 atgaccaaaa aggagaggtt gcaggaaaaa ggtcccgata tacgcttaga cactcggtat
    10921 agaatagctg gcttaaggcg agttgcgttt tacggttgtc tgctgctgta tccatcacat
    10981 cgtcttgaat taaatagtga gccatgacga acacgttgcc aagtgacagc ttgcggcatg
    11041 tctcgggggg cagttcggtg agttcttgca gccaaaatgg aagcaaatag catatgtaat
    11101 tacgcgtgct gtcttcccgc aacggattaa aacgcgccag atagtccaaa ccctcttgct
    11161 gaaagggagc tggaaacgtg gacgtccgtt cctccgcttg acgaaataca ttttccaatt
    11221 cgtttttgta tgcaaaatac cattccatcg ctatcacctg catctcttat gaatattttt
    11281 atagcgattt ctagttgtta tccgccatta tacaacagat tgcaattttc aagattttgt
    11341 tatttttaca ttgagaatgt tgtgaaaagg aatcgacaaa aatcccggcc gggaagatcc
    11401 cgccgggatt ttgtttttta aaattagatg atctccaaat agtcaatata agcatcccat
    11461 gttccatcat cggctgttac aacaagctca atctcttgat ttccggtgcc atggctgaca
    11521 ttgtttaaag tatagaccgc aggactgctc ccgccgaagt agaaggtacc cttcgtttga
    11581 ccaccaattt tcaagtcaac tttggccatg ttggaattat ttgaagcacc acggagtgaa
    11641 aaactatggg tgccactggt aaaattctgt gtgaatttca ctgaatcatt gttggagtat
    11701 aaagccactc cgttgaacgg cgagctgata tttgaagtgt actgcccgcc tttggtcata
    11761 ttctctgctt ccacttttgt gcctttgttt ggcggcgttt cgccgtctcc accatcaggc
    11821 gctaccgccc ggccattgct tggtgagatc ataccagagc aaaggttacg gtttttgagg
    11881 ttctgtgcaa tttgtggaat cgcttgaagt gtagtctggt actgatcatg catcagcatc
    11941 acatcgccgt ttttaaggtt gcccgcggca gctacgatct gtgcagtgga ggcgccgttc
    12001 cagtcttggg agtcaacgtt ccacaatact tcggtaagac cgttttgggt ctcgatggat
    12061 ttgagggttg cgtttgtttc gccatacgga ggacggaaca actttggtgc cgtgccagta
    12121 atggactgta tcgtttgctg cgttcgtgta atttccgatg acatctgcga tgtgctcagt
    12181 tgtgtcatat gcggatgtga ccatgaatgg ttaccgatcc acatgcctgc tgcctgctgt
    12241 tgacgtacaa gcgaagaatt gttttgcgcg ttttgtccaa gattaaagag cgtcgcgcgt
    12301 aaaccgtttt gcttcagagc actaagcagc gctttagtgt tagagggatt gggaccatcg
    12361 tcaaaggtta acgctacata accgttcgag caatcagccg catgcgcttg gttgctcgag
    12421 atcaccagcg agccagtgaa taaagacaag gtgattgaca taattgccgt ccattttcct
    12481 gctttagcta taaacaaggc tgtacctcct taacaatttt aatagatagt aaggttagtt
    12541 gatctccaaa taatcaacat aagcatccca tgttccatca tcggctgtta caacgagctc
    12601 gatttcttgg tttccggtgc catgactgac attgtttaga gtatagacag cagggttgct
    12661 tccaccgaaa tagaaggtcc cctttgtttg tccaccgatt ttcaagtcaa ctttggccat
    12721 gttggagttg ttcgaggcac cacgtaatga aaaactatgg gtgccgctag tgaaattttg
    12781 cgtaaatttt accgaatcat tgttggcgta taaagccact ccgttgaacg gcgagctgat
    12841 attagaagtg tactgaccac ctttggtcat actttgggct actatttttg tgcttgtgcc
    12901 tggaggagtt tcagttccgc cgccggaatt gccgccaatt gtaactgtat tactagttac
    12961 attagcactt ccactgcttt ggtatccctc tacagtaagt gaagtttcat acaacttgcc
    13021 cactttcatg cccatgcttt cccatttttt gaaatgctcg ctaaccgata tggttccgct
    13081 tgtgcgtttg gatgtccgga cactccaata ctgttggaaa gttgttttgt ctcctttaat
    13141 ggaaggctgg tctacccgag tggtttcata aatatcatat gttcccccgt caacgttaaa
    13201 ggtgcccttg gatgttgcac ctggtggacg ccagcttccc cagctatcga cgatgtaata
    13261 ttctacgagc ggatcaactg cccatccata aacgcacaaa tacgaattac catttggctg
    13321 gtagtcggca ttgtagttta ccgaaatatt tccgatttgc tggtgtgtct tggtttcgtc
    13381 gaattttttg cctttacgga ataatgcatt tccaatgtta ctccactggg cactgaacgc
    13441 acccccatta ttaagagtca tacttgtgtt cccgtgatct ttccacaatt catagtagta
    13501 gttgtcatgg gtaccggttt ggttcgaggt gatcgttgtt gccgcctgtg catttactgc
    13561 gggtaagata agcgaaaaac aaatcaaaat tgataaaaat aaccgtattc ttttttgttt
    13621 cattggactt tcctccttgt gtgtaattgc atgtagtctg actatgatgc agtgcattct
    13681 gtagtagctt gatacaacat ttccttccaa aaatttaatt gtaatcgatt acaattggat
    13741 tttatcatat ttgccctaat attttacctg aaaaatttcg aattatattg tagaaagttt
    13801 agtacttcat tcttacttac cctacatgat aaggtttcca aggagtgcgt tcagatcgaa
    13861 gattggggtg taaccgtgat agaaatgttc atgagctcgt attttcccgg tcttgtgact
    13921 acttaatagt tgaaaatacg aataaaaata caggaaagag aaaatattaa attaaaaagg
    13981 gtgaaagaag ggcctgaata tgaaaaaaca atggaaatta atcactgcta ccctgtatgg
    14041 aggagtgatg atgtatggta gtgcagggat gatcgaagct gctggtataa agacaagccc
    14101 ccagatgcaa gctcttactc ctagtaactc tattcagggt gaggctgatc cagggcgcat
    14161 gcagtcacag gactgccatc gacaaggaca tgcttataag cacgggcatg gcaaacggcc
    14221 tggaggctgg gaccatcatc tgaacgaaaa agtagccaaa ctattgggta tcactcctgt
    14281 tcgcttagaa aatgagctgg gacaaggcaa atcgttgtcc gacatcgcta aaagcaaagg
    14341 aattaatgag gaacagctta taaataagct gaaaaatgaa atgaccgtcg atctgaaacg
    14401 gctcgtcaac cgcaaagggc caattacatt cgatcgtaag tccggcactt cgaatgaagc
    14461 tcaattgaag cgttagcagg ggataccgtg gcatatcttc atcttgaata agtcgaggag
    14521 cagatcgttt gacaacaaaa aaaaggatgg gggaaaccca tccttaaatt gcaacttcct
    14581 tatcgtgtac gatgtcatat ttagttactt tgccagtgta tttgtctacg taatagaatc
    14641 cataagttgc aatgtgatca gggaaatctt cgtaagctct taaagagtat tttgttcctt
    14701 ccaaaccttc aaccattaca tttaaattgt atttaacagc ttcgtttttt attttatcaa
    14761 aaagaatatt gatcgcttga ttttctgtaa taatattttg ctgtttacct aaatacagtt
    14821 tattatcaat gaggctgatt tgtctgcctt ctgcaattcc aatatcttta acagagatgt
    14881 atgtgtttcc gttgtaaatc aaggcctcgg cagtattctt ttttgtaccc tctaaaaaca
    14941 catcaaactt tttcacaaca gcatttacgc ttgttccaga tgcagccatt gcggttgcac
    15001 ctgtaatcat cgtaccaatg gttaagccca ctaatagccc ctttaatttg tcattcattt
    15061 taattacccc tttatgtatg ctaatttcct tattaataat attctaaata tcaccataca
    15121 taaagtgatt gttgtggggg agagcagaag agtcaactat ctttaaagag cttaaaaaaa
    15181 tcaatggttt ctcttaaatc ttcatcatcc gtataaatgt tcatcacctt gcctatttca
    15241 attgcaaagt ccacatactt atttggttta gccgcaatga tgttcttgtg tatctccaga
    15301 cccgttggat gattcacagg acttttatag gagacacctg ctatctccag taattcagtg
    15361 gcagaacaaa tggtcgctat cactttatta tcattattca gtgtattgat taaagctagg
    15421 agttgcttgt tcgtctttaa ttgagtgtta tctccaccag gtataattag gagttgaata
    15481 tcctcggcag acacttcatc aatggccacc gaaggcataa ctttaaaatc ctcataggaa
    15541 atcactgggt ctttggttac cccaatcgta acaatgtccc ctttggtttt cataaaatag
    15601 gttgctaaca taatctcaaa actcacataa ccatcataaa ttagaacatg tgatttcatt
    15661 cgtacaccta cttcaacatt agtttttagc tttgagtccg ttaagtgcgc ctttaggaag
    15721 tttacatata gtgaaaatat atcacctaga taggtttaat tccataattt acagcaaata
    15781 tagagttgaa agtttaaata accagtcgca caaaatcaac cagcgactgg ttatttagct
    15841 tcgctagaat atgagctgag cggcacctat aatagctttt taagctgggg aatacggtct
    15901 tgggatacgc caagccattc agcatattca ccttgcttgg ctgctggatg ctcacgcata
    15961 agtcttctta gcttctcaac caaatgttgt gaaggcgacc gatgtgctat ttaacttaca
    16021 cctatgtttc ccttcagatc gtttatgcat tttttacata aaaatgaatc cctgaaatag
    16081 cttaaatcct ggatcgaata gcataagtga cagcagactc caatatactt ccgcatactc
    16141 aataaacctg tttcacaatc taaataaaat tctaaagact caccagcttg aatacccata
    16201 gaggttcgca tctctttagg aataacaatt cgacctaacg tatccaatgg acgtgtcatg
    16261 cctgtatttt tcaaatgatc ttctcctttc atagtccaac atccaatgat ctcctaataa
    16321 aaatataaaa atcaataaag taaaagcatt tatgtttgtt ccaaaagatg gtattatcgt
    16381 gaaggaaaat caataattat actattagtt tccaaactat attgtttatt gaaattgaaa
    16441 ttctatgaaa atgctgaaag ggtggtttgt ccatggaaat cacacctacg atacaggcag
    16501 aaattcaaac ttatctgaaa cgaaaaggtt taacgatgac caagtttggt cacacgattg
    16561 atttgaatgt aggtacagtt agtagcattg tgaccggtaa ccgatctatt tctgttcacc
    16621 aactggatag tattactgcg ggaatgaatt taccaccgga ttatttttac gaacgttata
    16681 ttgaagaatg ccttgaagaa tctccgctaa actggaaaaa aatcagccct ttcctatacc
    16741 gatgtattga actaggacga ctggactgct tacagcgagt ggtaattctg ttattggata
    16801 accctaatta tctgccatca ctctttgaag ttgccgaaaa tgtatacaaa gacggttaca
    16861 atgaagcagc ggcatacctt tacaaaaagg tggctgaaag tgagaagcag cagcattcag
    16921 agcgattggc gatctgccag tatcgtttgt tccaaatcaa tattggacaa gatagagctg
    16981 taaatcttca ggctgccatt gaatttgccc cttttgttga tcgtttagac gagatagagc
    17041 aattagatgc attaaaagat ttggcaaacg tgtacagatc attaagcatg tgggacaagg
    17101 tgtatgaatt ttcatctcaa atgggtcaaa tgggaaagat ccaatataat ttggttaata
    17161 actctaagcg aaaaggaaca gagccacgaa aaaagctaag caggccactg tttgtataca
    17221 tagtttactc cgagttgctg tgtgctaatg cttgcgatgc aaaaggtgat catgaacagg
    17281 cattagaaca tattcgaggt tatgccgatc taagttgggt gaaggagaag gatcctgatt
    17341 cactttattg gaagaagcaa tatcaacaat gggcgaaaat taatacgtac gtcaacaggc
    17401 ttatgtccgg ggatattagt gttctccccg attacgtaga acatatggct gctgaaaatg
    17461 agattttttc cgagctacta aacgtccttg aagttgctaa tcggtacaat gtagatgtag
    17521 accatatcct taagcgtttt gaatcccaaa ttgcagcgta tcaggaaccg ttgtcttctg
    17581 acatgtatac acaacaagtt ttaccggaag aatacgtacg cttctggtat aaaatggcta
    17641 agtatagcct atataaaggt agatatccat atggtttcaa atgtttaata aacgcgtttg
    17701 aaaaagctgt tacaattaac catgtactac ttattgccaa ttgttttgga ttattttttc
    17761 atttcaaaac acatgcggct cccgaaacac agacacagtt ccaatctatt tatgaggagg
    17821 tgtgggagaa aaatgatcaa aaggatggct ttcttcttgg cggtaactag ctttttactg
    17881 gtattcacag taccagtcca agctggaaat ctaagccatg acacgatcca aacacaagga
    17941 cacgttggtg gatcttgacc aagcactaat tcattaccct ggaccagctt attgctggtc
    18001 tctttttgta ttattttgta atttttcggc tcaaaaaaga ttatgacgta tttgtacatc
    18061 cctccttaaa atgaaattca ttaggaggta tgcaggatga gcaggtatga aacggtgccg
    18121 ttaattcaac agatggaaca cgccagacaa caattgcatg atctttacga agagtatggc
    18181 ttcggacatg cttgtgtact tcagcagtct atgcttttgg atgaactgat taatcagtac
    18241 aaccgtatgt ttcagaccaa gaagctgcct cactatgttt agggctagat cattaacaac
    18301 gacgatatta tgttcagtac atcctctccc ttctttgtta tgcaaaactg taacttttcc
    18361 cgcgtaacgt ttatgattat tctatataat gacttatttt aaaataaaat acatattcat
    18421 gtcataaaat gttaatcttt tttttgaggg gacggcatac taaggcaaca aaaaaagcag
    18481 agctcaataa gtgagccctg cccaaatcca ttggaattat aaccccatgc tgaaatacag
    18541 acgcacaaga ttagccaagc tcctgcgtgc ttttggaagc acgtttggag gaaagaaact
    18601 ggaaacgaaa cgaatgccaa ttcaatcgct gtctgccttt agagccaaca atccagttgc
    18661 cgccaggcag atgggcaaag agccagctta tgcccagaga aacacttgcc acgacgataa
    18721 acgtaatgag cgtagctgta aaatgatgat cgcccagtgc aagcgggcgg gtgtagtagg
    18781 atatgaaggc cagcacgagt gcatgggcca gatatcctcc aaaagaataa cgtccgatcc
    18841 agttcagcat acggcgaaac ggctcggatc gcgtatcttt ttgcaaatgg agcagcagtc
    18901 cgtacaataa aagcaactgc gacacaatta gaacaaaggt acttggcttc aaataggtcg
    18961 aaatattaag attgatcgta tcgcccgact ggatcagcat cgtgtgaccc atgagcatga
    19021 acaaaccaat aaagacaaat acattccacg gcaacgtctg tttggccagt ccacgccagg
    19081 tgtctgtcat gtaagcacat actgcgccca gcataaaata gaaaaagtac atgacaaagt
    19141 tataggtgcg ataatccagc agagtctgcc aaaaggacgg taaccgagtg ctccatgcag
    19201 acatgtcata gtaggaccat tgtaacagca aagcataaac cgcagcggca atcagcataa
    19261 tagccaaaac aagctgtttg cgtcttttcg tgctgtaacg acgtagaaac gcttgaacct
    19321 gcccggctgc ttttgaaaat aaaggaaaca aaatataaaa ctgaaagatc atcactacaa
    19381 accatagatg atatccgctg acggggatga tcatttcctc gaacatacct ttgtaaaagt
    19441 aaatatttcc ccactgcgcc gttgaccagt tttgagtaca tacccaataa ataacagtcc
    19501 agcaaaggaa aggaacataa atatctcgaa accgcctgcc aatatagcga ggatagccaa
    19561 tcggtttgtt gccgttataa aaaagcagcg ccgcagacag gaaaacgaac gttggtgtgc
    19621 caaaacgtgt caaatgatac agcatcgcga gcataacaga atctggctgt tggatgtcgc
    19681 tgcgataaat atattcgcca atgcaatgct gaagcacaac agcgaggtag gcaaggcccc
    19741 gtagttctgt ccactccgcg atacgcggct tactcatcca tatcactcct tttccgcaag
    19801 atacgcacat gtttttccta gcacaattgt aggtattgta acgtagaaac attagtgcag
    19861 gattaacgcc acctgaaagt aagaagagtg aagtagttcc attttgatat gattgcgttt
    19921 acaatctaag taaaaccaga ataaattaaa gtgaatttat aacttaagga tacacacagg
    19981 aagaggagag gaaggatgaa aaaaacgctg ctggtatata tgctgttgat tgcggccttt
    20041 gctctctatg tgttcaggta tgaacaaacg ggcccgttga atggcacttg ggaggataag
    20101 gggctacgag gcagcatcgg agaaacctat atgatgatta ccttccagtc tggtttggag
    20161 tattggaaaa gtgggctcaa gggcttcgag gatgccgggg atgcgctggg ggtgactgtg
    20221 gagtatcggg gagctac
//
