LOCUS       NZ_CP073683            21455 bp    DNA     circular CON 15-MAY-2024
DEFINITION  Paenibacillus sp. S25 chromosome, complete genome.
ACCESSION   NZ_CP073683
VERSION     NZ_CP073683.1
KEYWORDS    RefSeq.
SOURCE      Paenibacillus sp. S25
  ORGANISM  Paenibacillus sp. S25
            Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae;
            Paenibacillus.
REFERENCE   1  (bases 1 to 5958851)
  AUTHORS   Li,T., Mann,R., Kaur,J., Spangenberg,G. and Sawbridge,T.
  TITLE     Transcriptomics differentiate two novel bioactive strains of
            Paenibacillus sp. isolated from the perennial ryegrass seed
            microbiome
  JOURNAL   Sci Rep 11 (1), 15545 (2021)
   PUBMED   34330961
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5958851)
  AUTHORS   Li,T.
  TITLE     Direct Submission
  JOURNAL   Submitted (20-APR-2021) Agriculture Victoria Research, AgriBio, 5
            Ring Road, Bundoora, VIC 3083, Australia
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 31-MAR-2020
            Assembly Method                   :: Unicycler v. 0.4.8
            Assembly Name                     :: AVR_PaeniS25_1.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 200.0x
            Sequencing Technology :: Illumina NovaSeq; Oxford Nanopore MinION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_019454085.1-RS_2024_05_15
            Annotation Date                   :: 05/15/2024 03:29:11
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,267
            CDSs (total)                      :: 5,136
            Genes (coding)                    :: 5,079
            CDSs (with protein)               :: 5,079
            Genes (RNA)                       :: 131
            rRNAs                             :: 12, 12, 12 (5S, 16S, 23S)
            complete rRNAs                    :: 12, 12, 12 (5S, 16S, 23S)
            tRNAs                             :: 91
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 57
            CDSs (without protein)            :: 57
            Pseudo Genes (ambiguous residues) :: 0 of 57
            Pseudo Genes (frameshifted)       :: 21 of 57
            Pseudo Genes (incomplete)         :: 38 of 57
            Pseudo Genes (internal stop)      :: 14 of 57
            Pseudo Genes (multiple problems)  :: 14 of 57
            CRISPR Arrays                     :: 4
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 06:16:07
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 373807
            Orig. end                         :: 395262
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP073683.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from AgriBio, 5 Ring Road,
            Bundoora, Victoria 3083, Australia.
            Annotated using prokka 1.14.6 from
            https://github.com/tseemann/prokka.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21455
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RRE-containing"
                     /region_number="2"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     cand_cluster    1..21455
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21455
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:11455](+)"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11455
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     misc_feature    367..379
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 20.49"
                     /tool="antismash"
     misc_feature    711..726
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: medium, score: 21.42"
                     /tool="antismash"
     gene            complement(1185..3347)
                     /gene="bglX"
                     /locus_tag="KAI37_RS01625"
                     /old_locus_tag="KAI37_00329"
     CDS             complement(1185..3347)
                     /EC_number="3.2.1.21"
                     /GO_function="GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="bglX"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013308372.1"
                     /locus_tag="KAI37_RS01625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KAI37_00329"
                     /product="beta-glucosidase BglX"
                     /protein_id="WP_220031424.1"
                     /transl_table=11
                     /translation="MEQHLNSYLENMTLEEKVDQLLQLVGAFFEEAGTDSQITGPMASL
                     GITEKNVHNVGSVLGIAGAKEAIRVQQAHLSKNRLGIPLLIMADIVHGFKTIFPIPLAI
                     GCSWDMQLAEESATIAAREAAVSGVHVTFAPMVDLVRDPRWGRVMESTGEDPYLNSEFA
                     RAFVRGFQGKDLTNDTDRVAACVKHFAAYGAGEGGRDYNTVDVSAWQLREYYLPSYKAA
                     LDEGCEMVMTSFNTVEGVAATGNKRLMRDLLRDEWGFDGVLISDWAAIKELIPHGIAED
                     EREAAKKALLAGVDIEMMTSCYNGHLPELVRSGQLDEALIDEAVMRILKLKQKLGLFEN
                     PLRGADPEREREVVFCEAHRTVAKELAIKSCVLLKNDSVLPLNRNQHIALIGPFAESGD
                     ILGSWSWSGSQEEAIRVVDGFQSKISSSLLTVAAGFSTDDITEEQYAEALQAASQAEVI
                     VLALGERSDMSGEAGSRSNIRLPQAQLELVKRLKTLNKPMVAVLFNGRPLDLHGVIEEA
                     DAVLEAWFPGGEGGAAIADLLYGDAEPTGRLTMSFPQTVGQVPVYYNHFNTGRPQLDPN
                     TKERYVSQYLDVPNEPLFPFGYGLSYTDVAYDSVQLSGDTLIPGQELTIKVQVTNTGTR
                     PVEETVQFYVRDISGDTVRPMKELKDFCKVLLAPGESREVEFALTEPQLRYHHADLSFS
                     SDSGEFAVFTGPNSRDTSESRFRLVK"
     misc_feature    complement(3408..3421)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 21.18"
                     /tool="antismash"
     gene            3951..5204
                     /locus_tag="KAI37_RS01630"
                     /old_locus_tag="KAI37_00330"
     CDS             3951..5204
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1143: sugar-binding lipoprotein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017425689.1"
                     /locus_tag="KAI37_RS01630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KAI37_00330"
                     /product="extracellular solute-binding protein"
                     /protein_id="WP_220030601.1"
                     /transl_table=11
                     /translation="MMKRTLGIILASTLLLGGALAGCSSKDDSSGKDANGKTTITMWGM
                     GAEGKLLPEIVKDFEKENPDIHVDVQALPWDNAHDKLLTAVASKSGPDVVQLGTSWVPE
                     LASAGALTDITPYISKYPELESKNFFEGAVGTTKFEGKPVGVPWYTETRVLFYRSDLLK
                     QVGYNEAPKTWGELSDAAQKLAARGKGKYGISFSAKEQSMGFMFALQNGSKLVDEQGNP
                     LFNQPPFVDAVKYVNTFFQNGSNAVDIGIDSVQGLQGEGIVPMFISGPFMIKEIKSKAP
                     ELEGKWNIAELPGKVNNLSVLGGANLSIMKFSKHPEESAKFLAYMSKPETQLKWMDLSS
                     NLPATTKSWEDAKLKSDPMLRTIRKQLDHSAALPQLAAWEEVSQQFIKSFERIYRGHAD
                     VQKEMDDFNQQAASIMKK"
     gene            5241..6125
                     /locus_tag="KAI37_RS01635"
                     /old_locus_tag="KAI37_00331"
     CDS             5241..6125
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1067: putative ABC
                     transporter permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014279338.1"
                     /locus_tag="KAI37_RS01635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KAI37_00331"
                     /product="sugar ABC transporter permease"
                     /protein_id="WP_071639192.1"
                     /transl_table=11
                     /translation="MKGSSQKLAPYLFIGPSIILLTLFSLLPILLALVISFTDMDLSGL
                     VNYDSIRFIGLENYTNVLLDPSFIKSLGNTLFFVIIGVPLVLIFSLSIAILINMGKSRA
                     FKVFRVVFYLPSVTNVVAVAVVWSYLYNPTLGLFNYVLGMMNLGPVPWLTDPTVAKVSL
                     IVLAVWRGIGLNMIIFIAAIKGIPGSYYEAAQLDGANTWQQIRYITLPQLRYAIFFVSI
                     TTMIGWLQFFEEPFVMTKGKPLDGTLTASLFIYNNGFQFSKFGYAAAGSFILFFAIIAV
                     TLIQFRLQNKAES"
     gene            6144..6998
                     /locus_tag="KAI37_RS01640"
                     /old_locus_tag="KAI37_00332"
     CDS             6144..6998
                     /GO_process="GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1069: putative ABC
                     transporter permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013308375.1"
                     /locus_tag="KAI37_RS01640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KAI37_00332"
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="WP_071639196.1"
                     /transl_table=11
                     /translation="MKTAVQQARANTRSGEKTFQWFVAILLTVGGLLMVLPFAWMILSS
                     FKTEGEVTKIPPTIWPQHFTLDNFKLLFDSMAFGTYLTNTLIIVLASFFGLFLNAMAGY
                     GFAKFQFKGKGFLFYLVLATMMIPGQVTMIPVYLILNQMGLTNSMLGIVLPGLVGAFAI
                     FLFRQFMSDIPEELLEATRLDGAGEFRTFLQIVLPISTPILAVQAILTFIGGWNSFLWP
                     LIIANDEKLYTLSVGLSLLKGQNESQFALQMAGSTFMVVPIMIIFIIFQKYIIENYTIS
                     GIK"
     gene            complement(7092..7769)
                     /locus_tag="KAI37_RS01645"
                     /old_locus_tag="KAI37_00333"
     CDS             complement(7092..7769)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF016430.4"
                     /locus_tag="KAI37_RS01645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KAI37_00333"
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="WP_345945616.1"
                     /transl_table=11
                     /translation="MSFLKIGINVYDWNIQKSFIFLSVQRGLEQMPTTMVIDCCKEDQC
                     RGSSRCFYRKICELYLSEVYRFCMHLIKNQSCFKFMAEECTQDTFVAARQQLVKLKHHP
                     NVKGWLYLTAKNLIYKSFRCYYTQKKHETTFDCEKICGFSNSVDEEWENRRLGDVDTVI
                     VNILMQLSKNEYTLYQDYFCRQLAVPLLATKYNISVTATTTRIYRLKRKLRTLSHQYCL
                     THI"
     gene            7897..9639
                     /locus_tag="KAI37_RS01650"
                     /old_locus_tag="KAI37_00334"
     CDS             7897..9639
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013308379.1"
                     /locus_tag="KAI37_RS01650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KAI37_00334"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_220030603.1"
                     /transl_table=11
                     /translation="MKESIVYKRLAATFRPYLKTVTIILICLILSAGLNILLPLTSKII
                     VDQGLLKGNMQAVILYTSAAFLIVCLDKLLNVCKEIFRAGLSAQVTFSLFEKAYLHLTR
                     VRMSYFNRTNEAELLNQIGTDVGNVSRITDSGVFFVIMQAFSMIGGICGLLLINWKMTV
                     IVLCFLPIKYVVVKYFVKRRKKLVGNLIEGSSDFAQWFGESVGGMKEQRMFGLIPHKHQ
                     QFSSKQRRIVESERKLSLLDAWNIASESILIQLLMMLLYVVGANLIFRLQLTVGGIFAF
                     VSYSAYVTTPVFAILNIGYMLAEVVPSAIRYYQFLDWAEEETSNSVTPASIVTEPPFED
                     HIAFHNVSFSYTKDEPVLPHVSFRIARGEKVAIIGANGAGKSTLLDLIMRFSQPDQGII
                     TYDGIDIQSYEIDEYRSQIALVSQQVYLFDTTIFGNIRIGTEVTNDAIEAIIAEVGLEE
                     LVQNSADDFPIGSNGSMLSGGQRQKIAMARALIREAPLFILDEVTSNLDTAARLNVQQL
                     LKTRLRDKTVIIVTHRSEILAHVDRVILLENGEPAQIGSHSHFMTCHAEYRGWVLGEEE
                     VSIK"
     gene            9744..9929
                     /locus_tag="KAI37_RS01655"
                     /old_locus_tag="KAI37_00335"
     CDS             9744..9929
                     /GO_component="GO:0005575 - cellular_component [Evidence
                     IEA]"
                     /GO_function="GO:0003674 - molecular_function [Evidence
                     IEA]"
                     /GO_process="GO:0030152 - bacteriocin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:TIGR04065.1"
                     /locus_tag="KAI37_RS01655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KAI37_00335"
                     /product="CLI_3235 family bacteriocin precursor"
                     /protein_id="WP_071559456.1"
                     /transl_table=11
                     /translation="MRKLVKRSTNVGDTIEAFGCGCSCYCPCSCYCAGSLTRSSNTQRE
                     SDGSYRRDNGTGIGNY"
     aSDomain        10001..10378
                     /aSDomain="Other_Sactipeptide_rSAM_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing rSAM protein in a sactipeptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_KAI37_RS01660_Other_Sactipeptide_rSAM
                     _RRE.1"
                     /evalue="1.30E-14"
                     /identifier="RREFam021.1"
                     /label="KAI37_RS01660"
                     /locus_tag="KAI37_RS01660"
                     /protein_end="126"
                     /protein_start="0"
                     /score="45.3"
                     /tool="antismash"
                     /translation="MNMCQPFIYTFQTRLHHYVYDVNTNLILRIKEEAYHFLNSHSSFD
                     LDQMEATPELQQYIRDLLDNGFLSSQRPQIMNHPKTKHLEHMLQHQLKTLTLQVTQNCN
                     LRCSYCVYSGGYDNRGHTSLMM"
     gene            10001..11455
                     /gene="ccpM"
                     /locus_tag="KAI37_RS01660"
                     /old_locus_tag="KAI37_00336"
     CDS             10001..11455
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /GO_process="GO:0030152 - bacteriocin biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0046500 - S-adenosylmethionine metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="ccpM"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Other_Sactipeptide_rSAM_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PTHR43273"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013308381.1"
                     /locus_tag="KAI37_RS01660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KAI37_00336"
                     /product="Cys-rich peptide radical SAM maturase CcpM"
                     /protein_id="WP_256703340.1"
                     /sec_met_domain="Other_Sactipeptide_rSAM_RRE (E-value:
                     2.3e-12, bitscore: 45.3, seeds: 13, tool:
                     rule-based-clusters)"
                     /sec_met_domain="PTHR43273 (E-value: 4.6e-54, bitscore:
                     182.1, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 9.7e-13, bitscore: 47.1,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 3.4e-10, bitscore: 38.6,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNMCQPFIYTFQTRLHHYVYDVNTNLILRIKEEAYHFLNSHSSFD
                     LDQMEATPELQQYIRDLLDNGFLSSQRPQIMNHPKTKHLEHMLQHQLKTLTLQVTQNCN
                     LRCSYCVYSGGYDNRGHTSLMMDFETARKCIDFVIDRSVDSDRLDFGFYGGEPLINFPL
                     VKKCVEYIKEQVAYRDVGFHLTTNGTLLNDDILDFLDEHRFVLTISLDGDQENHDRNRR
                     FAVNGRGSFDTIIANVDKIKRNYPDLFEWINFNVVLDTRNDFGCINDFYTNYETFESLY
                     SVRSSYINDAYVKDEILYRNEFIEQRGYEVVKMMLSKFGRVDENHVSKLIKDYYIQMYF
                     RMFHYRKPSAGMPIEAHHGGPCVPGVQRLFADVHGNLYPCERVSEQSEVVQIGKVDTGF
                     EVDKISQILNVGTITEDACKNCWNFRFCTLCVAVADDLHTLSKEKKLSHCSVVKNDIRH
                     TLLDYCMMNELGYDFSEDTILDFEKA"
     gene            11467..12591
                     /locus_tag="KAI37_RS01665"
                     /old_locus_tag="KAI37_00337"
     CDS             11467..12591
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013308382.1"
                     /locus_tag="KAI37_RS01665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KAI37_00337"
                     /product="TIGR04066 family peptide maturation system
                     protein"
                     /protein_id="WP_220030604.1"
                     /transl_table=11
                     /translation="MTNKLIIFPFDYETIALVRNLNLLGSYEEVVLISFQGSGLIGKDA
                     CVTDKGEATGFIVKPESCLEQEMERCDAILLVKSNFKLDVAEVYLPVIKKAGQLGKKVM
                     CNFTLPDSCMEFIEPCEEQDDKLILKNTFDVRTKDILPPDPGSVIHDFFTPVLFVLGLN
                     ERTHKLNLQLNLRQKLEAQGYRVSQITSNGCGELIGAHSFPQFMFESGMTETQKIIMFN
                     RYLKKIEQSEKPDLILVGIPGGIVPFNNTFTNYFGVTSFLVSRAVRPDGLICCLHYDEY
                     NIKYLEHVKQYMENRFSSSLLGYAICNNVFDSYSSSTVNMQYASVDHRFVEEKKQELSN
                     YSVPVLHLSNDEDMNRLTKDILHYFSVDHHVVQL"
     gene            12605..12880
                     /locus_tag="KAI37_RS01670"
                     /old_locus_tag="KAI37_00338"
     CDS             12605..12880
                     /GO_component="GO:0005575 - cellular_component [Evidence
                     IEA]"
                     /GO_function="GO:0003674 - molecular_function [Evidence
                     IEA]"
                     /GO_process="GO:0030152 - bacteriocin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013308383.1"
                     /locus_tag="KAI37_RS01670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KAI37_00338"
                     /product="peptide maturation system acyl carrier-related
                     protein"
                     /protein_id="WP_220030605.1"
                     /transl_table=11
                     /translation="MNFTQDVKGTGMKLENIFWKLFKIKAGEINKEATLLGPDMGLFPR
                     DLVYLLFEVEKSFAILIPEERIVGGGLLTYNSLYETIKDCLSVEKE"
     misc_feature    complement(12889..12903)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 21.52"
                     /tool="antismash"
     gene            13004..13786
                     /locus_tag="KAI37_RS01675"
                     /old_locus_tag="KAI37_00339"
     CDS             13004..13786
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013308384.1"
                     /locus_tag="KAI37_RS01675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KAI37_00339"
                     /product="muscle M-line assembly protein unc-89
                     Uncoordinated protein 89"
                     /protein_id="WP_076293867.1"
                     /transl_table=11
                     /translation="MNVSFTSSHQSPFRTADHNRLELRHPLSAQAERKSIGKPQNKVIE
                     QLTEQKQSLMERRSDYLSNALKRGLGPEAVKAEMEEIDKQIQQIDENIQKQSLEEQKKA
                     LGMDEESKKEAQKGKKEEYTPKTAEEQQQRLITYTMHSIVSANNELKSAKIAKTAQITL
                     GSEAKGWENANPAKSAALREKAEGLNGKIMEIAANINERISEAVNNEPMVTDRVEPKDE
                     QESNAEADRVWTEQELNAYLDSAKDGAKTAGTKVNIAV"
     gene            13937..15523
                     /locus_tag="KAI37_RS01680"
                     /old_locus_tag="KAI37_00340"
     CDS             13937..15523
                     /GO_function="GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S8"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1075: alkaline serine protease, subtilase family"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013308385.1"
                     /locus_tag="KAI37_RS01680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KAI37_00340"
                     /product="S8 family serine peptidase"
                     /protein_id="WP_220030606.1"
                     /sec_met_domain="Peptidase_S8 (E-value: 4.8e-11, bitscore:
                     40.7, seeds: 43, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNGKIHVAIIDDGVNAGFLNTQLLYNVEIAHGDVEDGRTLNHGTL
                     CAAIVQTYFPDAIISSVKTMNHRKGNAAQLCAALDWCVKHGVQVANISLGSINYRDRGI
                     LREAVNNAAMAGLIMVCAAQNGGLLTYPASFANVIGVRCDHSGILTAGQYTYDAEKAFS
                     SGIDFTAFAKHELVGAAGEAVQCPNSNSYATPLITAHICKVLQQSKPVPSIEQLKHILH
                     KYSYLPVQDTIIPVMRYGHPDWIRRAYVFIEDCAISSKAPYYFQTQWKAQLSGDKIVAI
                     FEQAILQEREQQDTALEGGQRVYDLTDTIVLLGEMEPVSLQEVEQLASRYGKHVVYISK
                     NQRYIPALNFSSCYLRWWQQEGGLFMSQEEAIAIEDSRIPLICIYYDKGIDIIYFLHEL
                     RGGFARDGYQSWIAVDQSSAVLHDMEYTLSSDASIGLQELLYNAGTMAYNAYTDIAILC
                     VEATNITHCTKERVLLDVDIELSLLLKAETERIYISIRTEQGYLKEWVLSNLNVGDIGC
                     IYTYLEQLLVD"
     misc_feature    complement(15622..15642)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 24.71"
                     /tool="antismash"
     gene            15740..17254
                     /locus_tag="KAI37_RS01685"
                     /old_locus_tag="KAI37_00341"
     CDS             15740..17254
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019685877.1"
                     /locus_tag="KAI37_RS01685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KAI37_00341"
                     /product="alpha-N-arabinofuranosidase"
                     /protein_id="WP_025723872.1"
                     /transl_table=11
                     /translation="MAAAVKAKMIVDKSFRIAEVDKRIYGSFVEHLGRAVYGGIYEPTH
                     STSDESGFRNDVKELVKQLDVPIIRYPGGNFVSGYNWEDGVGPVASRPRQLELAWRTVE
                     PNEVGTNEFFKWAKDVGSEVMMAVNLGTRGIDAARNLVEYCNHTGGSYWSDLRRSHGVE
                     QPHKIKTWCLGNEMDGPWQIGHKTAEEYGRLAVESAKAMKLIDPDIELVSCGSSSSTMP
                     TFPEWEATTLDHTYEVADYISLHQYYGNHDNDTANYLARSMDMDHFIHTVISTCDYIKA
                     KKRSKKKMMLSFDEWNVWYHSNDADKKIDPWSVAPPQLEDIYNFEDALLVGSMLITFLR
                     HADRVKMACLAQLVNVIAPIMTENNGKAWKQTIFYPYLHASRYGRGVSLMPVVDSEKYD
                     SKDFTDIPYLDSAVVYDEEGDALTVFAVNRHLSESLELTVDVRSFEGYRIVEHTVLEHD
                     DLKATNSPAGEKVTPHNGGNAKLEDGIVKAHLGKASWNVIRLAKSH"
     misc_feature    complement(17311..17327)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 24.36"
                     /tool="antismash"
     gene            17675..19570
                     /locus_tag="KAI37_RS01690"
                     /old_locus_tag="KAI37_00342"
     CDS             17675..19570
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0051082 - unfolded protein binding
                     [Evidence IEA]"
                     /GO_process="GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016820229.1"
                     /locus_tag="KAI37_RS01690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KAI37_00342"
                     /product="HSP90 family protein"
                     /protein_id="WP_071639206.1"
                     /transl_table=11
                     /translation="MSQTDQYRFQVNLGGMIDILANHLYSSPRVFIREVLQNATDAITA
                     RKELRKVAAESKVLKEDKALGDTASESNDYEGKVIVELSGSGEHQVLMIQDNGIGLSEE
                     DIHRFLSIIGQSSKKGADLLASETSFIGRFGIGLLSCFMVSDEIVVLTRSVKEGISMEW
                     RGKPDGTYTIRRLETELPVGTQIYLRCKPGSEFYYEPAHVEESLIYYGALLPYPVMLSV
                     DGETKRVNLPSTSWMQDPEQLRSRRSEVLDLGYRLMGERFSDFIPLRTASGRTGGIAFI
                     LPRSVNLNSKRLHRVYLKHMLVSDKAENVLPEWAFFIKSLIWTDELQPTASREYFYENE
                     QLDDVRSELGTCIREELLRMAQYEPDRLQHWIRLHELSMKALAVEDDEFLRIMYRWFSF
                     ESTFGRRELKELIREADGRPLHYTSTVDEYRQITHVAAAQSMLVINGGYIYDSDILEKL
                     PWIDSNLQTERLSPEEVSLSFTGLTQEERENYYGVLRVMDAALQPMRCRAELKRFEPAS
                     LPVLYTISQDALTLRSMENTVEETTSLFSNVLDSLKAGVQQNSGYSTLYFNLNNPVVAR
                     ILEATDTQMVAAATEMMYVNALMMGHYPMNRSELGLMNRSVLHFINWGLGNGQNS"
     gene            19595..20656
                     /locus_tag="KAI37_RS01695"
                     /old_locus_tag="KAI37_00343"
     CDS             19595..20656
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016820230.1"
                     /locus_tag="KAI37_RS01695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KAI37_00343"
                     /product="hypothetical protein"
                     /protein_id="WP_071639208.1"
                     /transl_table=11
                     /translation="MEDTIYDLMEQAQDLPGGAAKLALLEEAVRLADTSGLKALAYEIR
                     GEIVDCAIFNGYPLKSLIAFSWQLGQFDQNPEEYDPFELLWNYKWILGKVCSFSNISKT
                     QIEDLVEDMRRRYAEYGYNERPYYYYKFRIAMDMGELDEARRYLDTFRLIESDSMSDCE
                     ACEQSQMVRFYYLTGEDEQALAVAKPILSGRMKCAEVPHVTLSQVLLPLYRQGEVDQAK
                     DNHRKGYRLIRDDRDFLKTIAEHIEYLAIADPVQGIEVVERHLHMALDYESGLEQMYFY
                     ATMVSLLQKLDTSGEKRLIRLPASLEWGKEDRTLTEIIAYFRPLAESAAADFDRRNGNT
                     FYSDWLGKIVQTA"
ORIGIN
        1 taacgagctg ggaattgaac accccgtaca tataggaggt ggttgtaatg gtttcttcct
       61 tacctcctga gtaatgcccg cccattaaaa tgtgcccatg gggacgctct acacgaagct
      121 ctttggattt gagtacaaca tgctcatatc tgtccgtgaa aaaggaaagt agttcatcgc
      181 catcccgttc ttcttcctgc cgtttcggga aaagttgatt cacttcggca gcggttaagt
      241 ccagcgtgcg cagcggctca ccgatggttt gagctggagc cacacgccct gcctgaagat
      301 cacttgtcgc gtgtgccggt atgctggtct cggaagtgtc cgctagaacg gtagctactt
      361 cgtcgcgtgc ctttgtcacc agctcctgat actctagctt tgtcactgcg gctggatgat
      421 tgggctggaa cagaccgtaa aaagtaaagc gagcttcccc tgcaagtttc acccgctcag
      481 attgcaacgc ggtataggcg aattcgtatt ggtacacttc attggcgagc gagtcacgat
      541 ggagtgcttc cggctcattc gtttctttgt acgaaagtcc aaagaactga aatccgtcag
      601 tcgagtaacc aacagtgcgg gttaacgaac cttgttgaat gtatgggaac gcctgacttt
      661 gaggctggtt ttgacgtgag caaacggtgt agcctctttg ttcatcatgg tagacggtgt
      721 ggtcaatata ttgagacaaa taagcttcat tactgcgcac agcagcggta tcggcaatgc
      781 cgatatcctg accgtacacg atatctgctt ccacgtcatc gccctgtagg gttacatccc
      841 agaaccatac tcccaggcgg cttagcgtga aggtcacctg atagcctaca ccagcggtga
      901 aaccttccca aataatctgc tgatccgttt gtcggattac tcccggtgag cgaactccaa
      961 gcaggggagt gatacttaca ccggacggac ggtacaatct caagtacaga ttgttcaagg
     1021 aaccgtcgac tgaattggtc aacagttggt tgatcatcgt tgagccgtgg gcgatcttat
     1081 acacatcacc actgcttaag aaggtaaaag acaggtcgcc ggcccgcagc aaaatatttt
     1141 gatccagact tgtattcatc aaagggaacg cctcactttc ctgtttattt cactaaccga
     1201 aaacggcttt cactagtatc tcggctgtta ggtcctgtaa agacggcaaa ttcaccgctg
     1261 tcactgctga agctcaaatc tgcatgatga tagcgcagct gaggctcggt caatgcaaat
     1321 tccacttccc ggctttcgcc tggggcaaga aggactttgc agaaatcctt cagttctttc
     1381 attggacgaa ctgtatcacc gctgatatca cgaacataga actggacggt ttcctcgacc
     1441 ggacgtgttc ctgtgttcgt tacctgcact ttaatggtca gttcctgacc aggtataagg
     1501 gtatcgccgg aaagctgtac gctgtcatag gctacatcgg tgtaactcag tccatagccg
     1561 aacgggaata aaggttcgtt tggtacgtct agatattgag acacgtagcg ttcttttgta
     1621 ttcggatcta actgcgggcg tcccgtatta aaatgattgt aatacacggg cacctgtccg
     1681 accgtttgcg ggaaggacat ggtcagacga cccgtaggtt cggcatcacc gtacaacaaa
     1741 tcggcaatcg ccgcgccgcc ttcaccacca gggaaccagg cttccaatac ggcgtctgct
     1801 tcttcaatga caccgtgcag atccaacgga cgaccattaa ataatacggc taccataggc
     1861 ttgttcagcg tcttcaggcg cttcaccagt tccaactggg cttgtggcag gcgaatattg
     1921 gaacggctgc ctgcttcacc actcatatcg gagcgctcac caagcgccaa cacgataacc
     1981 tctgcttggc tggctgcttg cagagcttcc gcatattgct cctcagttat atcgtcggta
     2041 gagaaacctg ccgcaaccgt gagcagcgag gaggatattt tcgattggaa cccgtcgaca
     2101 acgcgaatag cttcctcctg tgaaccgctc cacgaccaag agcccaggat atcaccgctc
     2161 tctgcaaaag gtccgatcaa cgcaatatgt tgattgcgat tcaatggaag aacggaatca
     2221 tttttgagca acacgcaaga tttaatagct aattctttgg caaccgtacg gtgagcttcg
     2281 cagaacacaa cttcacgttc acgctcaggg tctgcgccgc gtagcggatt ttcgaacaag
     2341 cccagctttt gcttgagctt caatatacgc atcacggctt catcaatgag cgcttcatcc
     2401 agttgtccgc tgcgaaccag ctcaggcaga tgcccgttat agcaggaggt catcatttca
     2461 atatctacgc cagccagcag tgctttcttc gctgcctcgc gctcatcctc ggcgatgccg
     2521 tgagggataa gctccttgat ggcggcccaa tccgagatga gcacaccatc aaagccccat
     2581 tcatcacgaa gcaaatcacg catcaggcgc ttattgcccg ttgctgctac gccttctacg
     2641 gtattgaagg acgtcatcac catttcgcag ccttcatcta aagcagcttt gtaggagggg
     2701 agataatact ctcgcagctg ccatgcggat acatctacag tgttgtaatc ccgtccgcct
     2761 tcgccagctc catatgcggc aaaatgcttc acgcatgcgg ccacccggtc ggtatcgttc
     2821 gtcagatctt taccctgaaa cccgcgcaca aacgcacgag caaattcgct gttgaggtaa
     2881 gggtcttccc ctgtagattc catcacacgg ccccagcgcg ggtcacgcac tagatcgacc
     2941 ataggagcga atgtgacgtg aacaccggat acagccgcct cgcgggctgc aatggtagcg
     3001 ctctcttctg caagttgcat atcccatgag caaccaatgg ccagcggtat agggaaaatc
     3061 gttttgaagc cgtgtacaat atctgccata attaaaagcg gaatacccag acgattttta
     3121 ctcaaatgag cctgctgaac acgaatcgct tccttggccc ctgcgatacc aagcacggaa
     3181 ccgacgttat ggacattttt ctctgtgatg ccgagagaag ccatggggcc ggtaatttga
     3241 ctatccgttc ccgcttcttc aaagaaggca cccacaagct gtagcagttg atcgactttt
     3301 tcttcaagcg tcatgttttc taaataggaa ttcaggtgtt gttccatcat aatcctccat
     3361 aagctgtatt gttggtggac agctcttttt tttcagattc atgagatttt ttggataaaa
     3421 ttgattcaaa aaagtgctga acaggctaat agctagtata gaagcataat attctgtcgt
     3481 attattaatc gaaacgtttc tattgttgaa ctcagttgga ttatatacgc tttcaaatgg
     3541 agagtcaaat ccaattcagg gggtttttat aggctaaata acgtaataaa gatgatataa
     3601 acgaaaaaaa gtcgggattc tgtgcaaata aaaaataata tttctattga atacggtttc
     3661 aatttgttct ataatgacta tcgaaacgtt tctattgacg ggtatggtcc ttgtgctttg
     3721 aacataagtg ttatagcggt atgctttaat cgctatgtat ttacatgcat caggatttta
     3781 caaaatttcg attccagtcg ctcgaaagtg caatatatag atgaactaga ccatttcgat
     3841 ctatataatg ttcattggaa gtcgcttatt gaatttttgc aaaatcctcg tatttgaatc
     3901 cgttatcata ttgcatgatc ggtaaaccga tcatctcggg aggaattcgt atgatgaaaa
     3961 gaacgttggg gatcattttg gcaagtacct tattactggg gggcgcgctg gcaggctgct
     4021 cgtccaagga tgattcgtct ggcaaagatg cgaacggcaa gacgactatc accatgtggg
     4081 gcatgggagc ggaaggaaaa ctgctgcctg aaattgtaaa agattttgag aaagaaaatc
     4141 cagatattca cgttgatgta caggcgttac cttgggataa cgctcacgat aagctgctga
     4201 cagcagttgc ttcaaaatcc ggtccggacg tggttcagtt aggtacatca tgggttcccg
     4261 aacttgcgtc tgcgggtgca ttgacggata ttacccctta tattagcaag tatcctgaac
     4321 tggaatcgaa gaatttcttc gagggtgctg taggtacgac aaaatttgaa gggaaaccag
     4381 tcggtgtgcc ttggtacact gaaacgagag ttttgttcta tcgttctgac ctactgaaac
     4441 aagtcggata taatgaagca cctaaaacgt ggggagagct ttccgatgct gctcaaaagc
     4501 tggcggctcg gggcaaaggc aaatatggca tctcctttag tgcaaaggag cagtctatgg
     4561 gctttatgtt tgctctccag aacggttcca agctggttga cgagcagggc aatccgctgt
     4621 tcaatcaacc accgtttgtg gatgctgtga agtatgtgaa tacctttttc caaaatggct
     4681 ctaacgcagt ggatattgga attgattccg ttcaaggttt gcaaggcgag ggtatcgttc
     4741 caatgtttat cagcggtcct ttcatgatta aagaaatcaa gagcaaggca ccagaattgg
     4801 aaggtaagtg gaatatagcg gagcttcctg gcaaagtaaa caacctgtcc gttttgggtg
     4861 gagccaacct ttcaattatg aaattcagca agcacccaga ggagtcggcc aaattcctgg
     4921 cttacatgag caaaccagaa acacagctga aatggatgga tctgtccagt aacttgcctg
     4981 caactactaa atcgtgggaa gatgccaaac tgaagagtga tccgatgctt cggacgattc
     5041 gcaaacagtt ggatcattcc gcagcattgc cgcaactggc cgcatgggaa gaggtttctc
     5101 aacaattcat caagagcttc gaacgtattt accgcggtca tgccgatgta cagaaggaaa
     5161 tggatgactt taatcagcag gctgcaagta taatgaaaaa ataatgatcc atatccgtca
     5221 ttgtcaaagg gagtgaaggc atgaaaggaa gctcgcagaa gcttgcgcca tacttgttta
     5281 tcggtccctc catcatcctg ttgacgctgt tttcgctgtt gccgattcta ctggcgctcg
     5341 taatcagctt cacggatatg gatctgtcag gacttgttaa ttatgatagt attcgcttta
     5401 taggtctgga aaattataca aacgtactat tggacccttc ctttataaag tcccttggta
     5461 ataccctgtt cttcgtcatc atcggtgttc cgttggtgct gatattttcg cttagcatcg
     5521 cgattctgat taacatgggt aaatcacgtg ctttcaaagt attccgcgtt gtgttctatc
     5581 taccgtccgt aacgaatgtg gttgcagtcg cagtcgtttg gagctacctg tataatccga
     5641 cgcttggatt attcaactat gtacttggta tgatgaattt aggtcccgtc ccatggctga
     5701 ccgatccaac agtagcgaaa gtttcgttga ttgtgttagc agtttggcgg ggcatcggct
     5761 taaacatgat tatttttatt gcggctatta aagggattcc gggttcttat tatgaagcgg
     5821 ctcagcttga cggtgccaat acatggcagc aaattcgtta tattacgctt ccgcagcttc
     5881 gttacgctat tttcttcgtg tccatcacga cgatgatcgg ctggctgcaa tttttcgagg
     5941 aaccgtttgt catgaccaaa gggaagccgc tcgacggcac gctgacggca tccctgttca
     6001 tttacaataa cggcttccaa tttagtaaat tcgggtatgc cgcggcggga tcgttcattc
     6061 tgttcttcgc gatcatcgcg gtgacgctga ttcagttccg tttgcaaaat aaagcggagt
     6121 cctgatagag agaggtgatg aacgtgaaaa cagctgttca gcaagcccgc gccaatacgc
     6181 gcagtggtga aaaaacattt caatggttcg tggcgattct cctgaccgtg ggaggtctgt
     6241 tgatggtgct gccttttgcg tggatgatat tatcctcctt taagacagag ggtgaggtaa
     6301 ccaaaattcc tccgaccatc tggccgcagc attttacact ggataatttt aaattactat
     6361 tcgatagcat ggcttttgga acctatctga cgaatacgct gatcattgtt ttagcttcct
     6421 tcttcggatt attcctcaat gccatggcgg gttatggctt tgccaaattt caatttaaag
     6481 gcaaagggtt tctattctac ctggtactgg caacgatgat gattccaggt caagtgacga
     6541 tgattcccgt ctacttgatc ctgaaccaaa tgggattgac caattccatg ctggggattg
     6601 tccttcctgg attggtaggc gcgttcgcga tcttcctgtt ccggcagttt atgtccgata
     6661 tcccggaaga attgctggag gcgacacgtc tcgatggagc aggggagttc cgtacttttc
     6721 tgcaaatcgt attgcctatc tcgacaccaa ttctggcagt acaggccatt ttaaccttta
     6781 tcggtggatg gaatagcttc ttgtggccgc tcattattgc gaacgatgag aagctgtaca
     6841 ccttgtccgt cgggttgtca ctgctcaagg ggcagaacga aagtcaattt gcccttcaaa
     6901 tggcaggctc gaccttcatg gtcgttccaa tcatgattat tttcattatt ttccaaaagt
     6961 atattatcga gaattataca atttcgggga ttaaatagta gtgtagtgtg aatacaagtc
     7021 atagtcacaa gaacgaacag cggagcttct ctttgggagg ggctccgcct ttttgcttta
     7081 cagggacata tttatatatg agttagacaa tattgatggg acaatgtacg aagtttcctt
     7141 ttcagtctgt agattcgagt cgttgtagcc gtaaccgaaa tattatattt ggtagcgagc
     7201 aagggcactg ccagttgtcg acaaaagtag tcctgataga gcgtatattc attttttgaa
     7261 agctgcatca gtatgttaac aataaccgta tccacatctc ccagccttcg attctcccac
     7321 tcctcatcta ccgaatttga gaaaccacat atcttctcac aatcaaacgt agtttcatgc
     7381 tttttttgtg tatagtagca cctaaatgat ttatatatga gatttttagc cgtaagatat
     7441 agccaaccct tcacattggg gtgatgtttg agcttgacca attgctgtct tgccgctaca
     7501 aaagtatctt gtgtacattc ttctgccata aatttaaagc aagactgatt cttgattaaa
     7561 tgcatacaga aacgatatac ctcgctcaga taaagttcac aaatttttct gtaaaagcat
     7621 ctggaactac ctctgcattg atcctctttg caacagtcga taaccatcgt agtcggcatt
     7681 tgttcaagcc ccctttggac ggataaaaaa ataaatgatt tttgtatgtt ccaatcatat
     7741 acattaattc caattttcaa gaatgacata aatcatattt aatctcgtaa atgtggaatt
     7801 actagaacag ttaaaagata ttttaaggtg attttgattc tgatacggaa ttagttaata
     7861 gggggagagg gtgcatctgg tgaaaggggg aaaaggatga aagaatccat agtatataaa
     7921 cgtttggcag caacatttag accttatctg aagacggtca ctatcatttt gatatgtctc
     7981 atcctatcag cgggcttgaa tatattactg cctttaacaa gcaagattat tgtggaccaa
     8041 ggtcttctga aagggaatat gcaggctgta atcctgtaca catctgctgc gtttttaatc
     8101 gtttgcttgg acaagctgtt gaatgtgtgt aaagaaatct ttcgggcagg cttaagcgca
     8161 caggttacct tttcattatt tgaaaaggcg tatctgcatc tgacaagagt acgaatgagc
     8221 tattttaacc gaaccaatga agcggagcta ctgaaccaaa ttggcacgga tgtaggcaat
     8281 gtatcgagga tcacagatag tggagtattt tttgtcatta tgcaggcgtt cagcatgatt
     8341 ggtggtatat gtggtttgct gctcattaac tggaaaatga ctgtaatcgt gctgtgcttt
     8401 ttacccatca aatatgttgt ggtgaagtat tttgtgaagc gtagaaaaaa actagtgggg
     8461 aatttaattg aaggcagtag tgattttgct cagtggtttg gggaatctgt cgggggcatg
     8521 aaggagcaac ggatgtttgg tcttattcca cataagcatc agcagttctc atccaagcag
     8581 cgtcgaattg tagaatcaga acggaaatta tcacttctgg acgcctggaa tatcgcttcg
     8641 gaatctattt taattcagct tctaatgatg cttttgtacg ttgtgggtgc taatcttatc
     8701 tttcgtttac agcttactgt aggtgggatt tttgcctttg tttcttacag tgcttatgtt
     8761 accactcctg tattcgctat tctaaacatt ggctacatgc tggctgaagt cgttccctcc
     8821 gccattcgat attatcagtt cttggattgg gcagaggaag aaacatctaa ttcagtcact
     8881 ccagcgtcta tagtaactga gccgccattc gaagatcaca ttgcatttca taatgtttca
     8941 ttttcctata ccaaggatga acccgtactg ccccacgtga gctttaggat tgcccgaggg
     9001 gaaaaagtag ctatcattgg agcaaatggg gcagggaagt ctacgttgct ggatctgatt
     9061 atgagattca gccagcctga tcaagggata atcacttatg acggcattga catccaaagc
     9121 tatgaaatag atgagtatcg aagtcaaata gctttggtca gtcagcaggt gtatttattt
     9181 gatactacta tttttggtaa tatccgcata ggcacagaag tcactaatga tgcaatagag
     9241 gccattatcg cggaggttgg tctggaagaa ttggttcaga actcggcaga tgacttcccc
     9301 ataggctcga acggctccat gttgtcgggt gggcaaagac agaaaattgc tatggcccgg
     9361 gcattgatca gggaagcgcc attgtttatt ctcgacgagg tgacctccaa tctagacaca
     9421 gcagctaggc taaatgttca gcaattgttg aagacccggt tgcgtgacaa gaccgtaatc
     9481 atcgttacac atcgcagcga gatattagcg catgtcgata gagttatttt gttggagaac
     9541 ggcgaaccag cccaaatagg atcacactcc cattttatga cctgtcatgc agaatacaga
     9601 ggatgggtat taggggaaga agaggtctcc ataaaatgat gaaaaaaaca aacgctttca
     9661 tagagtgatt taacaccatg tacggaatta gtataggtga acaccttttt aaatcatatc
     9721 atgaatggga ggagtagttt aacatgcgta agcttgtgaa aagaagcacg aatgtaggcg
     9781 acacgattga ggcatttggc tgtggttgtt cctgttattg tccttgctcc tgttattgcg
     9841 caggcagttt gactcgaagc tccaatactc agcgtgaaag tgacggttct tatcgcagag
     9901 ataacggaac tggaattggt aattattaag cttgtatctg tatggaggag cctgggcatt
     9961 ccaggcttct gtccacatca aaacagagta ggtgtgaatc atgaacatgt gccaaccctt
    10021 tatatacaca tttcagacga gactccacca ttatgtatat gatgtaaata ccaatttaat
    10081 tttgaggatt aaagaggagg cttaccattt cctgaattcg cattccagct tcgacctgga
    10141 tcagatggag gctacaccgg aattgcagca gtatatccgt gacttgttgg ataacggatt
    10201 tttatcttca cagcgtccgc agattatgaa tcatcccaaa acaaagcact tggaacatat
    10261 gcttcagcat cagctgaaga ccctcacctt acaggtaact caaaattgca atcttagatg
    10321 ctcttactgc gtttattcag gaggatatga caatcgaggt cataccagtc tgatgatgga
    10381 ttttgagaca gcccgcaagt gtatcgattt tgtcattgat aggtcagtag acagtgaccg
    10441 tttggatttt ggtttttatg ggggagagcc gcttattaat tttccgttgg tcaagaagtg
    10501 tgtggaatat atcaaggagc aggtagcgta tagagatgta ggctttcatt tgacgaccaa
    10561 tggtacgctg cttaatgacg atattctgga ctttctggat gaacatcgtt ttgtgcttac
    10621 gatcagtctg gacggagatc aagagaatca tgacagaaac agacgatttg ctgttaacgg
    10681 gcggggctcc ttcgatacga ttattgccaa tgtggataaa attaagagaa attacccaga
    10741 cctctttgaa tggattaatt ttaatgtggt gttggatacc cgtaatgatt ttggttgtat
    10801 caatgatttt tatacgaatt atgaaacctt cgaaagtctg tacagtgtaa ggtcgtccta
    10861 cattaacgat gcttatgtga aggatgaaat tttgtacaga aatgaattta ttgagcagag
    10921 aggctatgag gtagttaaaa tgatgctttc caagtttgga agagtagatg aaaatcatgt
    10981 ctccaagctg attaaggact attatattca gatgtatttc cgaatgtttc attatagaaa
    11041 gccttctgcg gggatgccga tagaagcgca tcatggcgga ccctgtgtgc ctggtgtaca
    11101 gcgattgttt gcggatgtgc atggaaatct gtatccatgt gaacgggtca gtgagcagtc
    11161 ggaggtggtg cagattggaa aggtggacac aggctttgaa gtggataaaa tcagccagat
    11221 tttgaatgta gggacaatca cggaggatgc atgtaaaaac tgttggaatt tccgcttttg
    11281 tacgctgtgt gttgctgtag cagatgattt gcataccttg tccaaagaaa agaagctgag
    11341 tcattgttcg gtagtcaaaa atgatattag gcatacctta cttgattatt gcatgatgaa
    11401 tgagctgggc tatgatttct ccgaggatac gattctcgat tttgaaaaag catgaggggt
    11461 gtctccatga ccaataaatt aatcattttt ccgtttgatt atgaaacgat agccctggtt
    11521 aggaacttaa atctattagg aagttatgag gaagttgtac ttatctcttt tcaagggtcg
    11581 gggttgatcg ggaaagatgc ctgtgtaacg gacaaggggg aagcgacagg cttcatagtg
    11641 aagccggagt cttgtttgga gcaagaaatg gagcgttgtg atgctatatt actggtgaaa
    11701 tccaatttca agctggatgt agctgaggtg tatcttcccg tgatcaagaa ggctggacaa
    11761 cttggcaaaa aagtcatgtg taatttcact ttgccagact catgtatgga attcatcgaa
    11821 ccctgtgagg agcaagatga caagctgatt ttaaaaaata catttgatgt acgcacgaaa
    11881 gatattttac cgcctgaccc gggctctgtt attcatgatt tttttacacc ggttctattt
    11941 gtattagggc tgaacgagcg aacgcataag cttaatttgc agcttaacct tcggcagaag
    12001 cttgaagcac aaggatatcg ggtgtcgcaa atcacatcta atggatgcgg ggagctgatt
    12061 ggtgcacatt cttttccaca gtttatgttt gagagcggta tgacggaaac ccagaagatt
    12121 atcatgttta atcggtattt gaaaaaaata gagcagagcg aaaagcctga tctaatactc
    12181 gtaggcattc caggtgggat tgttcccttt aacaatacgt tcacgaatta ttttggagta
    12241 acctcatttt tggtatcccg cgctgttagg ccggatggac taatctgttg tcttcactat
    12301 gatgaataca atataaaata tttggagcat gtgaaacagt acatggaaaa ccgtttttcc
    12361 tcttcattat taggatatgc catatgtaac aatgtattcg atagttactc ttcttccaca
    12421 gtcaatatgc aatatgcatc tgttgatcat cgtttcgtgg aagagaaaaa gcaggagctt
    12481 tccaattatt ccgtgcctgt actccatctg tccaacgatg aagatatgaa taggctgacg
    12541 aaggatattt tacattattt ttcggttgat catcacgtag ttcagttgta atggagggaa
    12601 gaacatgaac tttactcagg atgtaaaggg aacaggaatg aaactggaaa atatattttg
    12661 gaagcttttt aaaataaaag cgggtgagat aaataaagag gctacattac tgggtcctga
    12721 tatggggttg ttccccagag atctggtata tctattattt gaagtggaaa aaagctttgc
    12781 tatcctaatt ccagaagagc gtatagtggg aggggggttg cttacatata acagcttgta
    12841 tgagacgata aaggactgct taagtgtgga aaaggaatga aggatttgtg aaaatgatga
    12901 taaaacatac aaaaacatac aaaaaaatcc gataaacctc tagaatcact tatttcagga
    12961 ttttggaaaa atcctcattt aaaagagaat tggaggtttt aggatgaatg tatcatttac
    13021 atcatctcac caatcgccgt tccgcaccgc agatcacaac cgacttgaac tacggcaccc
    13081 cctttccgct caggctgaaa ggaagagtat aggcaagcca caaaacaagg ttattgaaca
    13141 attgacagag caaaagcaaa gtttgatgga gaggcgttcg gactatttaa gtaatgctct
    13201 caagcgtggt ctcggtccgg aagctgtaaa agctgaaatg gaagagatag ataagcagat
    13261 tcagcaaatt gacgagaaca ttcaaaagca gtcactggaa gagcaaaaaa aggctttagg
    13321 catggatgag gaaagtaaaa aagaagctca gaaaggcaaa aaggaagaat atacgcctaa
    13381 gactgctgag gagcagcagc aaagattgat cacctataca atgcatagta ttgtatctgc
    13441 aaacaatgag ttgaagagtg ccaaaatagc caaaacggca caaatcacgt tgggaagcga
    13501 ggctaaggga tgggaaaacg ctaaccctgc aaaatcagcg gctttgcgtg aaaaggcaga
    13561 gggacttaat ggaaagatca tggaaatcgc tgcgaatatt aatgagcgta tcagcgaagc
    13621 agtgaataac gaaccgatgg ttacagatcg ggttgaacct aaggatgagc aggagtcgaa
    13681 tgcagaggca gatagggtgt ggactgaaca agagctcaat gcctatctgg actcggctaa
    13741 agacggggcg aagactgcag gcacgaaggt aaatattgca gtctgatccg gctatcatgt
    13801 acatggttcg ctaaattagg agggtgcttt cagacgaacg ctatcgttcg cagaggcacc
    13861 ctccgcttac tctaatatgg aacggaacag agccgtgaga ttcatttcac aatccgaaga
    13921 gacaggggga gaaaaaatga atggcaagat ccatgtagcc attattgacg acggggttaa
    13981 tgctggcttt ttaaacaccc aattattata taacgtcgaa atagctcatg gagacgtaga
    14041 agatggacgc accttaaatc acggtacgct atgtgcagct attgtacaaa cgtattttcc
    14101 agatgcgatc atcagcagtg taaaaacaat gaaccataga aaaggaaatg cagctcagct
    14161 ttgtgctgcg ctggattggt gtgtaaagca tggtgtacag gtagccaata tcagcctggg
    14221 aagtataaat tatcgagatc gaggcatact gcgggaagct gtaaataatg cagctatggc
    14281 gggattaatt atggtatgtg cagcacaaaa cggaggactt cttacttatc cggcttcctt
    14341 tgccaatgtg attggtgtgc gctgcgatca tagcggtata ctcacagcag gacaatatac
    14401 atatgatgct gagaaagcat tctcaagtgg tatcgatttt accgcttttg ccaagcatga
    14461 actggtaggt gcagctggag aggctgtaca atgtcccaac agcaatagct atgccactcc
    14521 attgattaca gcacacatat gtaaagtttt gcagcagtcc aagcctgttc cttccataga
    14581 acagctaaaa catattttac ataagtatag ttatcttccg gtacaggata ccataatccc
    14641 cgtaatgcgt tacggacatc cggattggat acggcgcgcc tatgtgttta tagaggattg
    14701 tgcaattagc tcgaaagcac cctattattt tcagacccaa tggaaagctc aactctctgg
    14761 cgacaaaatt gttgcgatct tcgaacaagc catcctgcag gagcgagaac aacaggacac
    14821 agcgctcgaa ggtggacaac gggtatacga ccttacagat acgattgtct tgctagggga
    14881 aatggagcca gtgagtttgc aggaagtgga gcaattggct tcacgttatg gaaaacatgt
    14941 cgtctatatc tctaaaaatc aacgatacat ccccgcactg aatttctcat cttgctattt
    15001 gcgctggtgg cagcaagagg gggggctctt tatgtcgcag gaggaggcta tcgcaataga
    15061 ggattctcgc attccgctta tttgtattta ttatgacaag ggcattgaca ttatttattt
    15121 tttgcatgag ttgagagggg gatttgcccg ggatggatac caaagctgga tcgcggtgga
    15181 ccagtcctcg gcagtgttgc atgatatgga gtatacgctc tcttcggatg caagcattgg
    15241 attacaggaa ctgttatata atgcgggtac aatggcatat aacgcttata cggatattgc
    15301 tattttgtgt gtagaggcta cgaatattac gcattgcacc aaagaacgag ttttattaga
    15361 cgttgatatt gagctttctt tactgttgaa agcggaaact gaacgcattt atatatctat
    15421 acggacagag cagggctatt tgaaagaatg ggtcctctcg aatttaaacg tgggcgatat
    15481 aggttgtatt tatacatatt tagaacaact gttggtagac tgatattcac tcaataagtt
    15541 tgtttataaa acgaaatatt ttgaagtacg taaccaattg cttatcgttt acgattaatg
    15601 ttaataaata tgttaagtat ttaataataa tgttgactat aataaatatg gtgtgttata
    15661 ttaaaaccgt aaataaaacg gcttcttagt cttggtggta caacggattt tattttcgca
    15721 ttcagagagg atggtttagg tggcagcagc tgtaaaagca aagatgattg tagacaaatc
    15781 ttttcgtatt gctgaagtcg ataaacgcat ttatggctct tttgtagagc atctcgggcg
    15841 tgccgtatat ggcggcattt acgagcctac tcattcaact agtgatgaaa gcggtttccg
    15901 aaatgatgtt aaagagttgg taaaacagct tgatgttcct attatacgct atccgggagg
    15961 taactttgta tccggttaca attgggagga cggtgtcggc cctgtcgcgt ccagacctag
    16021 acagttggag ctggcgtgga gaacggtcga gccgaacgaa gtgggtacga atgaattttt
    16081 caagtgggcc aaggatgtag gttccgaagt catgatggcg gttaatttgg gtacgcgcgg
    16141 aattgatgct gcgcgtaatc tggtggaata ttgcaaccac acaggtggct cctattggag
    16201 tgatctacgt cgtagtcacg gtgtagagca accacataag attaaaacct ggtgtcttgg
    16261 taacgagatg gatggcccat ggcaaattgg tcacaagaca gcagaagaat atggccgtct
    16321 ggctgttgaa tctgcaaaag ccatgaagct gattgatcct gacattgagc ttgtatcctg
    16381 tggaagctcc agttccacaa tgccgacgtt cccagaatgg gaagcaacca cgctggatca
    16441 tacctatgaa gtagcggact atatttcctt gcaccaatac tacggcaatc atgacaatga
    16501 tacggctaat tatctggcac gttctatgga tatggatcat tttattcata cggtcatttc
    16561 gacttgtgac tatatcaaag caaagaaacg cagcaagaaa aaaatgatgc tcagctttga
    16621 cgaatggaac gtatggtacc actccaatga tgcggacaaa aaaattgatc catggtctgt
    16681 ggcaccaccg cagcttgagg acatctataa ctttgaggat gcattgttgg taggcagcat
    16741 gttgattacg ttcctgcgcc acgcggatcg tgtgaaaatg gcttgccttg cccaactggt
    16801 caacgttatt gcgccaatca tgaccgagaa taacggaaag gcgtggaaac aaacgatttt
    16861 ctatccgtat ctgcatgcct cccgttatgg tcgtggggta tcgctgatgc ctgtcgtgga
    16921 ttcggaaaaa tatgattcca aggacttcac agacatccct tatctggaca gcgctgtagt
    16981 ttatgatgaa gagggagacg cactgactgt ctttgcagtg aaccgtcatt tgtctgaatc
    17041 gctggagttg acagtagatg tacgcagttt tgaaggctac cgcattgtcg agcatactgt
    17101 attggagcat gatgatctta aagcgaccaa cagtccagcc ggtgaaaaag ttactcctca
    17161 caacggcggc aacgccaagc ttgaagacgg aattgtaaaa gctcatttgg gcaaagcatc
    17221 gtggaacgtt atccgtctcg ctaagtctca ttaattctct tctgtaaaag gtagagcttc
    17281 gactgtatct aaataagctc gcattctctc ttgtaagagt attacaagag cggcaatgcg
    17341 agctttttgc gtaaaatgag ccatttgtcc ctccatagat atagggttct aagagaaggg
    17401 tggattttaa ataaatatta tgtttattac taaatttaac taaacaaaga tgatccttat
    17461 tcactaattg ctcatactct ctacattttt atgaagttaa ttagacccag tgccagactt
    17521 cctaggtgaa aaaagaccct gttatatcgt tgtcaacgta ttgatatctg aaatgcaggg
    17581 tgtgcaatcc gacttaaatc cacgttatac tttaaaagac agtctattta aaaccagatg
    17641 atggttgtag catttcgaga aaggaatgat ctgtatgagt cagacagacc aatatcgttt
    17701 tcaagtgaac ttgggcggta tgattgatat tttggccaat catttatata gcagtccacg
    17761 agtgtttata cgtgaggttt tgcaaaatgc aacagatgcg atcacggctc gcaaggagct
    17821 gcggaaggtt gctgctgaaa gtaaagtatt gaaagaagac aaggcccttg gagatacagc
    17881 ttctgagagt aacgactatg aaggtaaagt catcgtggag ttatctggtt ctggggagca
    17941 tcaggtattg atgattcagg ataacggcat tggattgtca gaagaagaca ttcaccgttt
    18001 tttgtcgatt atcggtcagt cttccaagaa gggagccgat ttgctggctt ctgagacttc
    18061 gtttatcgga cgctttggga ttgggttact atcctgcttt atggtgagcg atgaaattgt
    18121 agtgttgacc cgctcggtga aggagggcat ctccatggaa tggagaggga agccggatgg
    18181 gacgtatacg attcgtcgct tggagaccga gctgcctgta gggacgcaaa tttatttgcg
    18241 ctgcaagccg ggaagtgagt tttattatga gccagcgcac gtagaggagt ctttaatcta
    18301 ttatggggcg ttgctgccgt acccggtcat gctgtctgta gacggggaga ccaagcgcgt
    18361 caatcttcca tcgacgagct ggatgcagga cccagaacaa ttgcgtagtc gccgtagtga
    18421 ggtgctggat ttaggctatc gcctgatggg tgagcgcttc agtgatttta taccgttgcg
    18481 gacggcatca ggcagaacag gcgggattgc attcattttg cctcgcagtg ttaatctgaa
    18541 cagcaagcgg ctacatcggg tgtacctgaa gcatatgctg gtgtcggaca aggcggaaaa
    18601 tgttttgcca gaatgggcat tcttcattaa aagcctgatt tggacagatg aattgcaacc
    18661 aacagcatca cgtgagtatt tttatgaaaa tgagcaactt gacgatgttc gttctgaact
    18721 ggggacctgt attcgggaag aactgctacg catggcgcag tatgagccag accgcttgca
    18781 gcactggatt cgtttgcatg agctgtccat gaaggcgctc gccgtggagg atgatgaatt
    18841 tttgcggata atgtaccgtt ggttttcctt cgaaagtacg tttgggcggc gtgagctgaa
    18901 agaactgatc cgagaggcgg acggacgtcc gttgcattac acatcgacag tagatgagta
    18961 tcgtcagatt acgcatgtgg cggcggcgca atccatgttg gtgatcaatg gcggctatat
    19021 ttatgattca gacattttgg aaaagctgcc ttggattgac tctaacctgc aaacagagcg
    19081 tcttagccct gaggaagtat ctctttcatt taccgggcta acacaggaag agcgcgagaa
    19141 ttattacggt gtgctacgtg tcatggatgc tgctttgcag ccgatgcgtt gccgcgctga
    19201 gttgaagcgt tttgagcctg cgagtttgcc agtgttgtat accatttctc aggatgcact
    19261 gaccttgcgc tccatggaaa acacggttga ggagacaacc tcactttttt ccaatgtgct
    19321 tgatagtctg aaagcaggag tccagcagaa ttcgggttat tccaccttat actttaatct
    19381 gaacaaccca gtggtggcgc gaattcttga agctaccgat acgcagatgg tcgcggctgc
    19441 tacagaaatg atgtatgtga atgcgcttat gatggggcac tacccgatga accgcagtga
    19501 gttgggactg atgaatcgga gtgtactgca ttttatcaat tggggattag ggaacggaca
    19561 aaattcgtaa ttgcgtaatt atagggggat ccaaatggaa gatacgatat atgatttgat
    19621 ggagcaggcg caggatctgc caggaggggc ggcaaagctg gcgcttctgg aagaagcagt
    19681 ccgcttggca gacacttccg gattgaaggc actcgcttat gaaatccggg gagagattgt
    19741 agactgcgct atttttaacg gatatccatt gaagtcgctg attgcttttt cgtggcagtt
    19801 gggccaattt gatcaaaatc cagaggagta cgatccgttt gagttgttgt ggaattacaa
    19861 atggatactc gggaaggtgt gcagcttttc caatatatcg aagactcaaa tagaagatct
    19921 ggtggaggat atgcgcagac gttatgccga atacgggtat aatgagcgtc catattacta
    19981 ttataagttc cgcatcgcga tggacatggg tgaactggat gaagcacggc ggtatctgga
    20041 caccttccgc ttgattgagt cggacagtat gagtgattgt gaagcctgcg agcagagcca
    20101 gatggtacgg ttctattact tgactggaga agacgagcag gcgcttgccg tggcaaaacc
    20161 gattttgtcg ggtcgcatga aatgtgcaga agtaccacat gtgacgctct cgcaggtgct
    20221 attgccgctt tatcgtcaag gcgaggttga tcaggcaaag gacaatcatc gcaaaggata
    20281 ccgcctaatt cgggatgacc gcgactttct gaaaacgata gcggagcata tcgaatattt
    20341 ggcgattgct gatccggttc aaggaatcga agtagtagag cgtcatctac atatggcgct
    20401 agactatgag agcgggctgg agcagatgta tttttacgcg acgatggtga gtctgctaca
    20461 aaagttggat acttcgggag aaaaacgatt gatccggttg ccggcttctt tggaatgggg
    20521 taaagaggat cgcacattga ccgaaatcat tgcgtatttt aggccactgg cagagtcagc
    20581 ggcggctgat tttgaccgac ggaacgggaa tacgttttat tccgattggc tcgggaaaat
    20641 tgttcaaacg gcatagaaga agtggtagct gtgaagaata ttttatacag cccaaacaat
    20701 gagcaggtat aatgttcctg tgaaatgaca ggaggggtta tgttgtgact gtaaccgaaa
    20761 aggtgattaa tttcgcacac cgcggagctt caggtgtatg tcctgagaat acgatggcgg
    20821 cattccgcca cgccttggaa ctgggagcaa caggtataga aacggatgtg cagcgtaccc
    20881 aagatgggca cctggtgctg attcacgatg agtcgctgga gcgtacgaca ggttgctcac
    20941 tggatgtaag ggatattacg cttgaggaat taaataaact ggatgcgggc ggttggtttg
    21001 atgagaaatt ccgaggtgag cgggtcccga tgctggatga gctacttgaa ctagcccagt
    21061 cctcgaatac aattattaat ttagagttga aaaacagcat ttatctctat ccgggtatgg
    21121 aggaagaggt cattgctgcc gtgaagcgtt ttgggttgga acagcgggta atcatatcca
    21181 gcttcaatca cgaatcgctg gcgctgtgtg cgcagcttgc tcctgaaatc aagacggggg
    21241 cgctgtatat cgaaattatg gttcgtccat ccgagtatgc aacccaattc ggagtaacag
    21301 cactccatgc ctacaaacaa gttgttacgc cagaagctgt atcagaggct ttggcattag
    21361 gcgtcgtcta ccacccatgg acggtgaatg agccagaaga aatgaagcgt ctgctggagg
    21421 ccggggtgaa cggcatcatc acggactatc ctgat
//
