LOCUS       NZ_CP050705            20822 bp    DNA     circular CON 07-SEP-2024
DEFINITION  Bacillus atrophaeus strain PENSV20 chromosome, complete genome.
ACCESSION   NZ_CP050705
VERSION     NZ_CP050705.1
KEYWORDS    RefSeq.
SOURCE      Bacillus atrophaeus
  ORGANISM  Bacillus atrophaeus
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
REFERENCE   1  (bases 1 to 4148820)
  AUTHORS   Boyetchko,S.M., Jones,S., Yu,M. and Dumonceaux,T.J.
  TITLE     Genome sequence of Bacillus atrophaeus strain PENSV20, a bacterium
            which antagonizes the growth of Sclerotinia sclerotiorum
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 4148820)
  AUTHORS   Boyetchko,S.M., Jones,S., Yu,M. and Dumonceaux,T.J.
  TITLE     Direct Submission
  JOURNAL   Submitted (26-MAR-2020) Bio-products and processes, Agriculture and
            Agri-Food Canada, 107 Science Place, Saskatoon, Saskatchewan S7N0X2,
            Canada
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: MAR-2020
            Assembly Method                   :: SPAdes v. March-2020
            Assembly Name                     :: AAFC_PENSV20_1.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 10.0x
            Sequencing Technology :: Oxford Nanopore MiniION; Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_019443725.1-RS_2024_09_07
            Annotation Date                   :: 09/07/2024 05:39:09
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,211
            CDSs (total)                      :: 4,099
            Genes (coding)                    :: 3,930
            CDSs (with protein)               :: 3,930
            Genes (RNA)                       :: 112
            rRNAs                             :: 8, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 8, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 83
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 169
            CDSs (without protein)            :: 169
            Pseudo Genes (ambiguous residues) :: 0 of 169
            Pseudo Genes (frameshifted)       :: 98 of 169
            Pseudo Genes (incomplete)         :: 119 of 169
            Pseudo Genes (internal stop)      :: 23 of 169
            Pseudo Genes (multiple problems)  :: 62 of 169
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 04:36:41
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1147819
            Orig. end                         :: 1168641
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP050705.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Susan M. Boyetchko.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..20822
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="3"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..20822
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20822
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:10822](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10822
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            346..1533
                     /locus_tag="HCU65_RS05650"
                     /old_locus_tag="HCU65_05670"
     CDS             346..1533
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003327670.1"
                     /locus_tag="HCU65_RS05650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HCU65_05670"
                     /product="DUF418 domain-containing protein"
                     /protein_id="WP_219947338.1"
                     /transl_table=11
                     /translation="MNQSPAPTQSDERIVSLDLLRGISILGILLVNIFDFKAPMAQTMT
                     IVQSMPGTISYWCEALIAIFIEGSFYPLFSFLFGTGAILFYERIRAKGLSFGAFYTRRL
                     LVLTAIGILHAVFVWSGDILFTYGILGFLLFFFLKRKKSVLLIWAVCLYCIPYGILSLL
                     MLLMLLVPAEEMQDLLGAPDQTAAIFQHGSFGDITAFRFSEWLTENVAVLPLSACIIVP
                     CFLIGIYAYKRGWFEKEISAGVKSELLVLMWCSLAAGLLLKLTPVWFGWNMTWIYIQQM
                     AGGPILALGYVSGFLLLWNKKRQAGSVLRMFSYVGRLSLTQYLFQTIFLSLFFYGYGLG
                     FYGMFSSAEMLGIALIFYACQLVFSRLWVQTFRYGPFEYVWRKLTYWRLPAFRKE"
     gene            complement(1496..1666)
                     /locus_tag="HCU65_RS05655"
                     /old_locus_tag="HCU65_05675"
     CDS             complement(1496..1666)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003327668.1"
                     /locus_tag="HCU65_RS05655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HCU65_05675"
                     /product="aspartyl-phosphate phosphatase Spo0E family
                     protein"
                     /protein_id="WP_003327668.1"
                     /transl_table=11
                     /translation="MNRKIEEKRMTLIETAQKFGMNSKEAIQCSQELDNLLNDGIKQDI
                     IPSEKREDANR"
     misc_feature    complement(1748..1768)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 24.35"
                     /tool="antismash"
     gene            complement(1818..2804)
                     /locus_tag="HCU65_RS05660"
                     /old_locus_tag="HCU65_05680"
     CDS             complement(1818..2804)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014479396.1"
                     /locus_tag="HCU65_RS05660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HCU65_05680"
                     /product="CotH kinase family protein"
                     /protein_id="WP_219947339.1"
                     /transl_table=11
                     /translation="METISLYFHPQQIQSNGSAAGLLVSESAASRILIRNRGGLNKKSY
                     VIEYENALHGKRTIYLNAEEHDPSLIRRRLAYHFFSQIGVLSPLASHVFLHINGREEGI
                     YVKIEAVDDHFLKERHMPLGAIYEARYTDPRIPLFGTENGLFNALSNMNTPKHDAYLQE
                     FLSFIHSAADDEFAVRIKTYLDVKLFYLWLIGSACTRHSSYFALYLNGDAGRFQIVPQE
                     TRELVLNTLADDDILLANGQTLAARLLAITAFKAQYHALLKNVLTREFTIDRLSQKIRE
                     WHLDICPRISGDPYISGTCSSLEREQTKILHDIEHRQALLHLQLATL"
     gene            2981..3886
                     /locus_tag="HCU65_RS05665"
                     /old_locus_tag="HCU65_05685"
     CDS             2981..3886
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388956.1"
                     /locus_tag="HCU65_RS05665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HCU65_05685"
                     /product="fumarylacetoacetate hydrolase family protein"
                     /protein_id="WP_003327666.1"
                     /transl_table=11
                     /translation="MKFATGELYNRIFVGLIIDDHKIMDLQKAEKKLFELETIPNTLAE
                     CIAEGDKFVAHARQLAEWAKKPNDELGSFIYSLSDVKLHAPIPKPSKNVMCIGKNYKDH
                     AIEMGSEADIPEYPMVFTKSPTTVTGHGDVINCHSQVTAQLDYEGELAVVIGKSGTHIS
                     KEEAYDHIFGYTIINDVTARDLQKKHKQFFIGKSLDSTCPMGPVLVHKSLIPDPQCLQV
                     ETRVNGELRQSGSTSDMIFSIAELIETLSKGMTLEAGDIIATGTPSGVGKGFTPPKFLQ
                     AGDSIDITIEPIGTLSNRMG"
     gene            3983..4339
                     /locus_tag="HCU65_RS05670"
                     /old_locus_tag="HCU65_05690"
     CDS             3983..4339
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388957.1"
                     /locus_tag="HCU65_RS05670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HCU65_05690"
                     /product="YisL family protein"
                     /protein_id="WP_003327665.1"
                     /transl_table=11
                     /translation="MTHMHIASWIVALILLFVSYGLYSSGSAKGAKITHMILRLFYILI
                     ILTGAELFIRFANFNGEYAGKMLLGIITIGLMEMILIRKKKEKSTGGLWIGFIIVLVLT
                     VLLGLHLPIGFHLF"
     gene            4538..7240
                     /locus_tag="HCU65_RS05675"
                     /old_locus_tag="HCU65_05695"
     CDS             4538..7240
                     /GO_function="GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S8"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1075: alkaline serine protease, subtilase family"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388958.1"
                     /locus_tag="HCU65_RS05675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HCU65_05695"
                     /product="S8 family peptidase"
                     /protein_id="WP_219947340.1"
                     /sec_met_domain="Peptidase_S8 (E-value: 2.7e-45, bitscore:
                     152.8, seeds: 43, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKRTKVSSFWASVLIFTLVISLFTPFREVSASGNTIEDASILENG
                     KEQTGMLKEPEQSQWYQISPGKDEIFNDSHMALSVKSESFLNVSVYASKEKAQKDETFD
                     MYRSYTAQEGKSEINIPHAWKGPYYIKVEYVGEEAEDGDAVAAENGESDKTTEAAYTIS
                     YKGTKLQPADLEEESCPVEMSVDQKKSGKDILKQLRAIRDDQLNQTALGKQMSGLYYKA
                     APFIVAKLALNKETRNAVYQDLVTLQPMFKDVSENGADSSYTITENDQKAITRLYETAI
                     KSVPSFLKKDMKKQAEQLKINQVKGKTAGAFLTENKLAPESNVQTGKVIFKVKDKKSLQ
                     SVNNEMKGFTASAQSKKDIENVKNAKKLFDNLYSFELPKDQKQNGLYTASAKRVKSAAS
                     SLSKMSNVEFAEPVQEYKSLSKDIQYSYQWPLKNNGEDGGVKGADVKSESANALLAKRK
                     LNDTLIAVVDTGVDSTLSDLEGKVRADLGRNFVGRNNNAMDDQGHGTHVAGIIAAESGN
                     GYSMAGLHAKANIIPVKVLDSTGAGDTEQIALGIKYAADKGAKVINLSLGGGYSRVLEF
                     ALKYAASKNVTIAAASGNDGESELSYPASSKYVMSVGASNRMDMTADFSNYGKGLDITA
                     PGSDIPSLVPNGNVTYMSGTSMATPYAAAAAGLLLSQNPKLKPDEVEDILKRTADDISF
                     DSVDGGEEELYDENGDPIEIPHIPGVDWHSGHGRLNVMKAVSAVDLQVKINKLEDTQTA
                     VRGTAKAGTAVEVKNGKKKLGSAKAGKDGKFKVNIPTQKKDQVLHINASLGDAKTSVKT
                     VVVKGKPSGAPKVNGVKAKDTAVKGKANSKAAIKVKNKSKKVIASAKADNKGAFSVKIK
                     KQKAGTVLYVTAADTDKKESKAVKVVVEK"
     gene            complement(7277..7846)
                     /locus_tag="HCU65_RS05680"
                     /old_locus_tag="HCU65_05700"
     CDS             complement(7277..7846)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003327663.1"
                     /locus_tag="HCU65_RS05680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HCU65_05700"
                     /product="DUF2777 domain-containing protein"
                     /protein_id="WP_219947341.1"
                     /transl_table=11
                     /translation="MKRKQYLFTEERKWEYGTIIVEDGICVIENEEGDMLLAESLPNTP
                     VYIQFNGVWEKAGISNSFAVIRDGRRIPLSGGESIRYEKSIKRPLMALLDSLDDETFLA
                     FLQHLRVFGLSVFDCVFSYNKGLFSGGSPEEEEGVSFYHFSNDEAQCALQHHYSRGSSS
                     NDRFEWTASDGKRSIMYSAVQRDGTE"
     misc_feature    7817..7835
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 23.25"
                     /tool="antismash"
     gene            8022..9863
                     /gene="asnB"
                     /locus_tag="HCU65_RS05685"
                     /old_locus_tag="HCU65_05705"
     CDS             8022..9863
                     /EC_number="6.3.5.4"
                     /GO_function="GO:0004066 - asparagine synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA]"
                     /GO_process="GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="asnB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GATase_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Asn_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177: asparagine synthase (glutamine-hydrolyzing)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016938277.1"
                     /locus_tag="HCU65_RS05685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HCU65_05705"
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="WP_003327662.1"
                     /sec_met_domain="GATase_7 (E-value: 1.5e-47, bitscore:
                     158.5, seeds: 307, tool: rule-based-clusters)"
                     /sec_met_domain="Asn_synthase (E-value: 2.8e-99, bitscore:
                     331.0, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MCGITGWVDFKKQLVQEKQTMNKMTDTLSKRGPDDTNVWGKHHVL
                     FGHKRLAVVDIEGGRQPMACTFQGNTYTIIYNGELYNTEDLRKELQARGHRFKRTSDTE
                     VLLHSYIEWQEECVHRLNGIFAFAVWDEKRNQLFAARDRLGVKPFFYTEKGSSFLFGSE
                     IKAILAHPDVPARVDRNGLAEIFGLGPSRTPGMGVFKGIKEVRPAHALTFTKDGLNMWR
                     YWNVESKKHTDSFGETVANVRYLFQDAVTRQLVSDVPVCTFLSGGLDSSAITAIAAGHF
                     EKEGKGPLHTYSIDYEENDKFFKASAFQPNDDGPWIEKMTEAFGTQHHKCVISQAKLVE
                     YLEEAVYVRDLPGMADVDSSLLWFCREMKKDFVVGLSGECADEIFGGYPWFHTADAEAG
                     FPWMRSTEERITLLQDSWQKKLNLREYVNAKYEETLAETPLLDGETGEDKVRRQLFYLN
                     MLWFMTNLLDRKDRMSMGASLEVRVPFADHRLVEYVWNIPWEYKMHDQREKGILRKALE
                     GILPDEILYRKKSPYPKTHHPEYTRAVSEWLKQLLSQKDSVLHTLLNKNKMDQLLETEG
                     SSFQVPWFGQLMKGPQLIAHLAQIHTWFEAYRIDIDE"
     gene            10001..10822
                     /locus_tag="HCU65_RS05690"
                     /old_locus_tag="HCU65_05710"
     CDS             10001..10822
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019713903.1"
                     /locus_tag="HCU65_RS05690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HCU65_05710"
                     /product="phytoene/squalene synthase family protein"
                     /protein_id="WP_219947342.1"
                     /sec_met_domain="phytoene_synt (E-value: 1.1e-42, bitscore:
                     144.1, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 1.5e-47,
                     bitscore: 160.2, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MADIKRAYQQCEEITKTHAPTCYQAFTFLPLKRRQAAYAVYAFCH
                     TAITIDDKDELSALERDAEQCLAGTYEENHFLWAALADAFRQFALEAEPFREFIAGIHE
                     NNEKTRFETLDELLMFAYQTGSTAGLMLLPILTKRNKEKLRQAAVSLGLAIQLTRMLRD
                     AGKDYRRKKRICFPQQAMRQFGYTEDDFCNETVNKAFVSTWEYVAFEAEAYAEECFDAM
                     SLFPRYSQSSVKAAASLYKAVLEKIRAEHYEVFTKNMTLTEEEADAILQQL"
     gene            complement(10854..12221)
                     /locus_tag="HCU65_RS05695"
                     /old_locus_tag="HCU65_05715"
     CDS             complement(10854..12221)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0042910 - xenobiotic transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0006855 - xenobiotic transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1086: MATE efflux
                     family protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388962.1"
                     /locus_tag="HCU65_RS05695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HCU65_05715"
                     /product="MATE family efflux transporter"
                     /protein_id="WP_061670485.1"
                     /transl_table=11
                     /translation="MKQAVLRQTALKQPADQKLSLFSLTWPIFIEVSLYMFMGNADTLM
                     LSQYSDNSVAAVGVSNQILNLIIVMFSFIATGTTIIISQFLGSKQKKEAIEVAYVSIGA
                     NFVISLVISAAVFMAAVPMLHMMGLTNDLMPDAKIFLQVVGGLSFIQALIMTFSAILKS
                     YGYTKDTMFVTIGMNVLNIAGNFLVIFGPFGLPVLGVAGVAMSTSIARVIGLIAMIVIV
                     NKRINLTLTLKKVFHVHKEHLRKLLKIGIPSAGEQLSYNISQMVITYFIAIMGAQALTT
                     KVYTQNITMFILLFGTAISQGTQILIGRYIGAKQFDNAYDRCMKSLYWALGIAAGTSVI
                     MSLFSKQLIGIFSQNPDIIATASMLIVMTIILEPGRSFNVIIINSLRAAGDAKFPVYMA
                     MISMWGIGLPLAYLFGIHLGFGLAGVWISFIADEWVRGILMYRRWRSRIWIQKGMA"
     misc_feature    complement(12233..12246)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 21.18"
                     /tool="antismash"
     misc_feature    complement(12234..12247)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 21.54"
                     /tool="antismash"
     gene            12344..13207
                     /locus_tag="HCU65_RS05700"
                     /old_locus_tag="HCU65_05720"
     CDS             12344..13207
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1287: AraC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388963.1"
                     /locus_tag="HCU65_RS05700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HCU65_05720"
                     /product="AraC family transcriptional regulator"
                     /protein_id="WP_010788183.1"
                     /transl_table=11
                     /translation="MPRIMFTVPPFPVFIAAGEGVFKKGEMHARRIFSVFDLIYVKQGT
                     LYITENDQTFSVGGGEYILLSPGLEHFGSRGCEENTSYYWLHFDEKRYEFTQKGGNNWA
                     ELLQEKGSFEEPARYRLALPRKGKVQRPLFMEKQFDSLMDYTAENSDLPLRKQILFEEL
                     LLHLQKESFQIPSAKERVAWDAARYLQEHYKERVTIKDLSYALHYHQDYVTRCMQQVLG
                     VTPGQYTNKVRMTEAKRLLSSTNDKMGVIAETIGMEDPTYFSKLFKQTEGVSPIEYRKI
                     VSRKIE"
     gene            13333..14277
                     /gene="cyoE"
                     /locus_tag="HCU65_RS05705"
                     /old_locus_tag="HCU65_05725"
     CDS             13333..14277
                     /EC_number="2.5.1.141"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0008495 - protoheme IX farnesyltransferase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006783 - heme biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="cyoE"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003327657.1"
                     /locus_tag="HCU65_RS05705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HCU65_05725"
                     /product="heme o synthase"
                     /protein_id="WP_003327657.1"
                     /transl_table=11
                     /translation="MDKPEAVFGFEQNRVTIKDYIKLVKPGIIISNSIAAFGGFWIAYV
                     SSEKALTGSAFFVTMLAAMIGTAFVMASGTVYNNYFDRKIDAKMARTRHRASVTGKMSA
                     ASIITFGTFLGIAGLGMLAALNVLTAVLGFLAFIFYAVIYTIWFKRTSVWSTVVGSFPG
                     AAPPLMGYCAVAGHIDMTAVVLYAIMFLWQPPHFWAIGIRRKEEYRAAGVPLLPVVKGN
                     HVTKISIHRYITVLVPVTLLLSFYVGLHHLSPLYFISALILGFIWIYKSYQGFKTDDDV
                     QWSKGMFIYSLFYFCILFFIMMIDSFVMAFFVQ"
     misc_feature    complement(14327..14340)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 20.84"
                     /tool="antismash"
     gene            14384..15418
                     /locus_tag="HCU65_RS05710"
                     /old_locus_tag="HCU65_05730"
     CDS             14384..15418
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1078: LacI family
                     transcription regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003327656.1"
                     /locus_tag="HCU65_RS05710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HCU65_05730"
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="WP_219947776.1"
                     /transl_table=11
                     /translation="MKKTIYDVAKAAGVSITTVSRVINNTGRISVKTRQKVMRVMKEMD
                     YLPNVHASALTGKRSNIIGLLTPDISNPFFGELAKSIEDRADELGFNIIICSTDHDSKK
                     ESKYFSILKQKSVDGIIFATGIENHDSMSALEDIVNDEIPLAMISQDKPLVPMDIVIID
                     DFLGGYAATNHLLSLGHRKIACIMGDGSTTGEKDRMKGFRQAMQEADVPIDDSLFVPTV
                     FSLKSGKEEAGKLFDRSMPTAIFAFNDVLACAAIQAARERGIKVPEDLSIIGFDNTVLA
                     EMVDPPLTTMSQPIPEMGRRVVELLVDEMKGKKTAKQKIMLPPELVIRHSTARLKDIPP
                     VRLS"
     gene            15683..16711
                     /gene="iolG"
                     /locus_tag="HCU65_RS05715"
                     /old_locus_tag="HCU65_05735"
     CDS             15683..16711
                     /EC_number="1.1.1.18"
                     /GO_function="GO:0050112 - inositol 2-dehydrogenase (NAD+)
                     activity [Evidence IEA]"
                     /GO_process="GO:0019310 - inositol catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="iolG"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GFO_IDH_MocA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GFO_IDH_MocA_C3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1079: oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003239393.1"
                     /locus_tag="HCU65_RS05715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HCU65_05735"
                     /product="inositol 2-dehydrogenase"
                     /protein_id="WP_219947343.1"
                     /sec_met_domain="GFO_IDH_MocA (E-value: 8.2e-36, bitscore:
                     121.2, seeds: 39, tool: rule-based-clusters)"
                     /sec_met_domain="GFO_IDH_MocA_C3 (E-value: 3.5e-28,
                     bitscore: 96.0, seeds: 4226, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTNQVRCAVLGLGRLGYYHARNIINEVRGAKLVSVCDPMKGRAEQ
                     VAEEFGLEKWTDNPDVILEDPNIDAVIIVTPTSTHAEMIKKAAEHGKQIFVEKPLTLNL
                     EESKEVIEKVKETSVICQVGFMRRFDPAYADAKRRIDAGEIGKPIYFKGFTRDSGSPPP
                     EFIKHSGGIFIDCSIHDYDIARYVMGAEITSVSGHGRILNNPFMEAYGDVDQALTYLEF
                     DSGAAGDVEASRTSPYGHDIRAEIIGTEGSIFVGTLRNQNVTILTSAGSNYEIIPDFQT
                     RFHEAYCLELQHFAECVQTGKRPLVTEIDATINLEIGIAATDSYKTGKPVKIHMDKIHA
                     DV"
     gene            complement(17218..17718)
                     /locus_tag="HCU65_RS05720"
                     /old_locus_tag="HCU65_05740"
     CDS             complement(17218..17718)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1250: DinB"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003327652.1"
                     /locus_tag="HCU65_RS05720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HCU65_05740"
                     /product="DinB family protein"
                     /protein_id="WP_219947344.1"
                     /transl_table=11
                     /translation="MNNIEQLYQYHTWANKRIVEHVKSLPADIANQETKSVFSSINEVL
                     FHMCQTDYIWLRTLLGDSFQDAIDDLSQFQGIRGQLEAIENQFLSLNGQYRDFFTRQKN
                     LDQPFSIYHQHYGTLDTTYAEIMQHIINHGTYHRGNITAMLRQLGHKGIATDYIQYLYG
                     LKQ"
     gene            complement(17771..>18177)
                     /locus_tag="HCU65_RS05725"
                     /old_locus_tag="HCU65_05745"
                     /pseudo=""
     CDS             complement(17771..>18177)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_process="GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009966965.1"
                     /locus_tag="HCU65_RS05725"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="HCU65_05745"
                     /product="LysE family transporter"
                     /pseudo=""
                     /transl_table=11
                     /translation="VVVQQIPVFETIMLTSRFLFLAYMGWVTWHRRPDPDETQKNVFSA
                     KKQAAFAAAVSLLNPHAILDTAGVIGTQSLPYTGLDKWLYTLSCIAVSWVWFIVLVLAV
                     RIFKTLDTGGGLMMY"
     gene            <18186..18845
                     /locus_tag="HCU65_RS05730"
                     /old_locus_tag="HCU65_05750"
                     /pseudo=""
     CDS             <18186..18845
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_1_2 (0-191). E-value: 2.8e-20.
                     Score: 64.7. Matches aSDomain:
                     nrpspksdomains_HCU65_RS05730_Aminotran_1_2.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019: aminotransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003224478.1"
                     /locus_tag="HCU65_RS05730"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="HCU65_05750"
                     /product="PLP-dependent aminotransferase family protein"
                     /pseudo=""
                     /sec_met_domain="Aminotran_1_2 (E-value: 1.7e-18, bitscore:
                     64.8, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="GTVLSKQQRQEMIRLTTNERMPIIEDEAYGDLWFEEKPPPPIKSM
                     DKEGNVLYLGTLSKTVSPGLRIGWVTGPEPVIERLADIKMQTDYGSSALSQWAAAKWLS
                     EGRYEEHLAWLRKELKDRRDATLHFLQRYAGDIARWNVPAGSFYIWVTFHQPLPFRRLF
                     NQALTKNVLLNPGSVYDPDDRQSLRLSYSYAALPDIGKGIKVLAETARQLMSEHTK"
     aSDomain        18189..18761
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_HCU65_RS05730_Aminotran_1_2.1"
                     /evalue="2.80E-20"
                     /label="HCU65_RS05730_Aminotran_1_2.1"
                     /locus_tag="HCU65_RS05730"
                     /protein_end="191"
                     /protein_start="0"
                     /score="64.7"
                     /tool="antismash"
                     /translation="GTVLSKQQRQEMIRLTTNERMPIIEDEAYGDLWFEEKPPPPIKSM
                     DKEGNVLYLGTLSKTVSPGLRIGWVTGPEPVIERLADIKMQTDYGSSALSQWAAAKWLS
                     EGRYEEHLAWLRKELKDRRDATLHFLQRYAGDIARWNVPAGSFYIWVTFHQPLPFRRLF
                     NQALTKNVLLNPGSVYDPDDRQSLRLSY"
     gene            complement(18857..19495)
                     /locus_tag="HCU65_RS05735"
                     /old_locus_tag="HCU65_05755"
     CDS             complement(18857..19495)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1286: Pentapeptide
                     repeat protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003327647.1"
                     /locus_tag="HCU65_RS05735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HCU65_05755"
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="WP_219947346.1"
                     /transl_table=11
                     /translation="MNTSTIQKPRIPETLTAASFGEGLTKDDQLEMCLIEDCSIIGEDI
                     ERICADQVVFRNVQFIDVSFRNIELTDVLFEKCDLSNADFSGAIIHRTEWRQSKLLGIN
                     LAEATMRNVLFSQCPANFSSFLFSNMKQVRFDQCSLLQCECNDAVLQHTHFDSCDLEGA
                     NFIGTSLQKMDISSCRFEQIHVSLEKLKGCKITPQQATVFARALGAVIK"
     gene            19861..20664
                     /locus_tag="HCU65_RS05740"
                     /old_locus_tag="HCU65_05760"
     CDS             19861..20664
                     /NRPS_PKS="Domain: Abhydrolase_1 (22-254). E-value:
                     2.6e-35. Score: 114.1. Matches aSDomain:
                     nrpspksdomains_HCU65_RS05740_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1036: alpha/beta hydrolase fold protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003327645.1"
                     /locus_tag="HCU65_RS05740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HCU65_05760"
                     /product="alpha/beta fold hydrolase"
                     /protein_id="WP_003327645.1"
                     /sec_met_domain="PF00561 (E-value: 2.6e-27, bitscore: 94.0,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 7.3e-18, bitscore:
                     63.9, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGHYIQTEEHVTLFVEDIGSGRPIVFLHGWPLNHQMYEYQMNELP
                     KRGFRFIGIDFRGYGKSDRPWTGYDYDTMADDVKAVIYTLQLEDAVLAGFSMGGAIAIR
                     YMSRHDEADIKKLILMGAAAPAFTKRPYYPYGFLKKDVDDLIVQFRNDRPKALADFGQL
                     FFEKHISPEFRQWFQELNLNASPYGTIHSAIALRDEDLRKELGDIKVPTLIMHGVKDKV
                     CPFDFAREMKRGIKQAKLIPFEESGHGLFFDEKEKLNNEIMRFSR"
     aSDomain        19927..20622
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_HCU65_RS05740_Abhydrolase_1.1"
                     /evalue="2.60E-35"
                     /label="HCU65_RS05740_Abhydrolase_1.1"
                     /locus_tag="HCU65_RS05740"
                     /protein_end="254"
                     /protein_start="22"
                     /score="114.1"
                     /tool="antismash"
                     /translation="PIVFLHGWPLNHQMYEYQMNELPKRGFRFIGIDFRGYGKSDRPWT
                     GYDYDTMADDVKAVIYTLQLEDAVLAGFSMGGAIAIRYMSRHDEADIKKLILMGAAAPA
                     FTKRPYYPYGFLKKDVDDLIVQFRNDRPKALADFGQLFFEKHISPEFRQWFQELNLNAS
                     PYGTIHSAIALRDEDLRKELGDIKVPTLIMHGVKDKVCPFDFAREMKRGIKQAKLIPFE
                     ESGHGLFFDE"
     CDS_motif       20131..20166
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HCU65_RS05740_0001"
                     /evalue="2.60E-03"
                     /label="NRPS-te1"
                     /locus_tag="HCU65_RS05740"
                     /protein_end="102"
                     /protein_start="90"
                     /score="10.4"
                     /tool="antismash"
                     /translation="VLAGFSMGGAIA"
ORIGIN
        1 ccgcgatcgg ctgatcgacc atatctttat cgtacacatt ggtcgtattt ttgtaattcg
       61 taagcgtgag attgtctcct gtaataaagc tgcctgcacc cgcaaatgtc ttgacctggc
      121 tttgggggga aatggtgatg caatcgccga tatgaacgac tccgctcgta ccgactgcat
      181 taattttaaa cgctccgaca atcgctggca tacgggcaca tcctttattg taaaaatgag
      241 gcaaaacaag taaagtgagt aaggatatac atccatttgg gctattcacg atagcttatg
      301 acaaatgcac atttttgtga gcgaaaaaac aaaggagaac gtaaaatgaa tcaaagtcct
      361 gctccaacgc agtccgatga gcggattgta tcgcttgatt tgctgagggg aatcagtata
      421 ttagggattc ttctagtgaa tatttttgat ttcaaagcgc cgatggccca aacgatgaca
      481 atcgtccaga gtatgcctgg aacgatttcc tattggtgtg aagcgctgat tgccattttt
      541 attgaaggaa gtttttatcc gctgttttct ttcctttttg ggacgggggc gatcctgttt
      601 tatgagagaa tccgcgccaa agggctttca tttggggcat tttatacaag aagactgctc
      661 gttttaacag cgatcggcat ccttcacgcg gtttttgtgt ggtctggcga tatattgttt
      721 acatatggca tcctcggttt tctgctgttt ttctttctga aacggaagaa gtctgtgcta
      781 ttgatttggg cggtgtgctt atattgtatt ccgtacggga ttttatctct tttgatgctt
      841 ctcatgctgc tggttccggc ggaagagatg caggatctgc ttggtgcgcc tgatcagacg
      901 gcggcgattt ttcagcatgg aagctttggc gacattaccg cttttcgatt cagcgaatgg
      961 ctgacggaaa atgtggcggt gctgccgctc tctgcttgta tcatcgtgcc ttgttttctt
     1021 atcggtattt atgcttataa aagaggatgg tttgaaaaag aaatatccgc gggtgtaaaa
     1081 agtgaattac tcgtgctgat gtggtgttcg ttagccgccg gtctgttgct taagcttact
     1141 cccgtgtggt ttggctggaa tatgacatgg atttacatac agcagatggc gggagggccg
     1201 attcttgccc ttggctatgt atcaggattc ctgctgttat ggaataaaaa gcggcaggct
     1261 ggctctgttc ttcgcatgtt ttcctatgtc ggcaggctgt cgctgactca gtatttgttt
     1321 cagacgattt ttttaagcct gtttttttac ggctacggat tggggttcta cgggatgttt
     1381 tcttcagcgg aaatgcttgg tatcgcgctg attttttatg cgtgtcagct ggtattcagc
     1441 agattatggg ttcaaacgtt ccgctacggt ccgtttgaat atgtatggcg gaagcttacc
     1501 tattggcgtc ttcccgcttt tcggaaggaa taatgtcctg cttaatgcca tcatttaaga
     1561 ggttgtccag ctcttggctg cattgaatcg cctctttgga attcatgccg aatttttggg
     1621 ctgtctcgat taaagtcatt ctcttttctt caatttttct gttcatcatg acggtctcca
     1681 actctcgaat ttattttgga aaacggagga tatggttagt ataacctatt tttgtataaa
     1741 aggttttctt tcgtcaatat gacaaaaaat gtgacaaaat tttatgttaa aagaaagcag
     1801 gcccggataa gagacagcta gagtgtggcc agctgtaggt gcaataaggc ctgccgatgt
     1861 tcgatatcat gtaagatttt tgtctgttcc cgttctaatg aggagcaggt gccgctgata
     1921 tatgggtcgc cgctaatccg cgggcaaatg tcaaggtgcc actctctgat tttctgagac
     1981 agacggtcta tcgtaaattc ccttgttaac acatttttta atagagcgtg atactgtgct
     2041 ttaaaggcgg taatagcgag cagtctggca gccagcgttt gtccgtttgc aagcaggatg
     2101 tcatcgtctg ccaatgtgtt caagacaagc tctcgcgtct cttgcggcac gatttgaaag
     2161 cggccggcgt ctccgtttaa ataaagggcg aaataggatg agtgccgggt gcaggcgctt
     2221 ccgatcagcc ataagtaaaa aagcttcaca tcaaggtatg ttttgatgcg cacggcaaat
     2281 tcgtcatcag ccgctgaatg aataaaggaa agaaattctt gtaagtatgc gtcatgcttg
     2341 ggtgtgttca tattgcttaa agcattaaaa agcccattct ctgtgccaaa gagcggaatt
     2401 ctcggatcgg tatagcgggc ttcgtaaatc gcccccaacg gcatatggcg ctcctttaag
     2461 aaatggtcgt caaccgcttc gattttgaca taaatgcctt cttcccggcc atttatatga
     2521 agaaacacat gggaagcaag aggagagaga acgccgattt ggctgaaaaa gtgataggcc
     2581 agcctccgtc tgataagtga gggatcatgc tcctccgcgt tcaaatatat cgttcttttt
     2641 ccgtgcagcg cgttctcata ttctattaca taagatttct tattcaggcc gccccggttt
     2701 ctgataagaa tacgtgaggc tgcagattct gagacgagca ggccggctgc tgagccattg
     2761 ctttgtatct gctgcggatg aaaatataga cttatcgttt ccatattctt ttcctttcct
     2821 cctttacgcc atatgtatga tatgtacaag gagcatgtcc cgaaactgtg catctcgtta
     2881 ttctttgcct aaactcatga cggagaaaaa agggtttctc atttttaata gagaataaaa
     2941 taaatagcgc gttttgatat aaagacgatg ggggaataag atgaaatttg cgacagggga
     3001 actatacaac cgaatatttg tcggcctgat tattgatgat cacaaaatta tggatttgca
     3061 aaaggctgaa aaaaaactgt ttgaacttga aacgattccg aatacgcttg cggaatgcat
     3121 tgcagaagga gacaaatttg tggcgcatgc ccgccagctt gcggaatggg ccaaaaaacc
     3181 aaatgatgag cttggttcat ttatttattc actgtcagac gtgaaactgc acgcgcctat
     3241 ccctaagcca tctaaaaacg tgatgtgtat cgggaaaaac tataaggatc atgcgattga
     3301 aatggggagt gaggcagaca tacccgagta tccgatggta tttacaaagt cgccgacaac
     3361 cgtcacaggg cacggcgatg tgatcaactg ccattcacaa gtcactgcac agcttgacta
     3421 tgagggggag cttgcggtcg tcatcggtaa aagcgggaca catatctcta aagaagaagc
     3481 ttatgaccac attttcggat atacgataat taacgatgtc acagcccgtg accttcaaaa
     3541 aaagcataag caatttttca ttggcaaaag ccttgattct acctgtccga tgggaccggt
     3601 gcttgtacat aaatcattga ttccggaccc tcagtgctta caggttgaaa cgagagtcaa
     3661 cggcgaactg cgccagtccg gctcgacaag cgatatgatt ttttcgattg cagagttaat
     3721 tgaaacgctg tcgaagggca tgacgcttga agcaggggat attatcgcga caggcacgcc
     3781 gtccggtgtc ggcaaaggat ttaccccgcc gaagttttta caggcgggag acagcattga
     3841 cattaccatt gaaccaatcg ggactttatc aaatcgcatg ggctgattgt ccggctggct
     3901 ttttgagaaa ttcattttgt tgccggggac aagttcatgg tactataagt ggggtatatt
     3961 tatctgatag ggggaaacgt gtatgacaca catgcatatt gcatcatgga tcgtggcgtt
     4021 gattttgctt ttcgtcagct acgggcttta ttcttctggg agtgcgaagg gcgccaaaat
     4081 cactcacatg atcctgagat tattttatat tctcatcatt ttgacaggcg ctgagctatt
     4141 tatccggttc gccaacttta acggagaata cgccggaaaa atgctgctcg gcattatcac
     4201 gatcggctta atggaaatga tcctcatccg caagaaaaaa gagaaatcaa ctggaggctt
     4261 gtggatcggt tttatcattg ttctcgttct tactgtttta ctcggcttgc atttgccgat
     4321 cggctttcat ttgttttaaa agatgatccg gttaaaggac aaaatcctta accgggtttt
     4381 tttatgctct cagaaaacga tgtgcacaat atattagcaa attcatataa attccataaa
     4441 tatttaaaat taccttaaat gtccccttga ataactccga atctgttaaa ttatgatact
     4501 cttcaaaaag aatcagaatt tttcaggagg ttatgaaatg aaacgaacaa aagtgagttc
     4561 tttctgggcg tcggttttga tctttacgct tgtcatcagt ctctttacgc cgttcagaga
     4621 agtgtctgct tcaggcaata cgattgaaga tgcctcaatt ttggaaaatg gaaaagaaca
     4681 aaccggaatg ctaaaggagc cggagcagtc tcaatggtac caaatctccc cgggcaaaga
     4741 tgaaatcttc aacgattctc atatggcatt gtcggttaag agtgaatcct ttttaaatgt
     4801 aagcgtttat gccagcaaag aaaaagcgca aaaagacgaa acctttgata tgtaccgctc
     4861 ttatactgcg caagaaggaa aaagtgaaat caacattcct catgcctgga aggggcctta
     4921 ctacataaag gtggagtatg tcggggaaga agctgaagac ggggatgcgg ttgctgctga
     4981 aaatggcgaa tccgacaaaa ccacggaagc ggcgtacacc atcagctaca aaggaacaaa
     5041 gcttcagccg gctgatcttg aagaagagtc ttgtccggtg gaaatgagtg ttgaccagaa
     5101 aaagtcaggt aaagacattt taaagcagct gagagccatt cgtgatgatc agctgaatca
     5161 aacggcccta ggtaaacaga tgtccggcct ctattataag gcagctccgt tcatcgtcgc
     5221 taaacttgct ctgaataaag agacgagaaa tgcggtatat caggatctag tgacgctgca
     5281 gccaatgttc aaagatgtat ctgaaaatgg cgcggattct tcgtatacca taacggaaaa
     5341 cgatcaaaaa gcgataactc gcctgtatga aacggcaata aaatccgttc cttctttcct
     5401 gaaaaaagac atgaaaaaac aagcggaaca attgaaaata aatcaagtaa agggaaagac
     5461 ggcgggagca tttttaacag aaaacaagct ggcgcctgaa agcaacgttc agaccggaaa
     5521 agtcatcttt aaagtgaagg acaagaagag ccttcagtcc gtaaataatg aaatgaaagg
     5581 ctttacggcc agcgcgcaat cgaaaaaaga tatagaaaac gtgaaaaatg caaaaaaact
     5641 gttcgataat ctctattcgt tcgaactgcc gaaggatcaa aaacaaaacg gattgtatac
     5701 agcaagtgca aaacgagtga agagcgcggc ttcttcttta tcaaaaatgt ctaacgtaga
     5761 gtttgctgaa cctgttcagg aatacaaaag tctgtctaag gatattcaat actcctatca
     5821 atggccgctc aaaaataacg gagaagacgg cggcgtgaag ggggcggacg tgaaatctga
     5881 atcggcaaat gccctgcttg caaaacgcaa gctgaatgac acgctgatcg ctgttgtgga
     5941 tacgggcgtt gacagcaccc tttcagattt ggaaggaaag gtaagggcgg atttaggacg
     6001 caatttcgtc ggacgaaaca ataatgcgat ggatgatcaa ggacatggaa cacatgtcgc
     6061 cggtattatc gcggcagaaa gcggcaatgg atattcaatg gcgggtttac atgctaaagc
     6121 aaacattata cctgttaaag tgctcgattc caccggggcc ggagacactg agcaaatcgc
     6181 gctcggcatc aaatacgcgg ctgacaaagg agcaaaagtc atcaatttga gcctgggcgg
     6241 gggatacagc cgggtgcttg aatttgcgtt gaagtatgct gcatccaaaa atgttacgat
     6301 cgcggcggca agcggaaatg acggagaaag cgagctgtcg tatcctgctt cttctaaata
     6361 tgtaatgtca gtcggagcaa gcaaccgcat ggatatgacg gctgatttct caaactatgg
     6421 aaaagggctg gatatcacag caccgggttc tgatattcca agcttggtgc cgaacggaaa
     6481 cgtgacgtat atgagcggaa cttcaatggc gacgccatat gctgctgcgg ccgccggact
     6541 attgctttct caaaatccga agctgaaacc ggatgaagtt gaggatattc tgaagcgtac
     6601 agctgacgat atttcctttg acagtgtgga cggcggagaa gaagaactgt atgacgaaaa
     6661 cggtgatccg attgaaattc ctcatattcc cggcgttgac tggcattccg gccacggccg
     6721 tttgaatgtg atgaaggcgg tcagcgcggt agatttacaa gtgaagatca acaagcttga
     6781 agatacgcag acagccgtcc ggggaacagc aaaagcaggc accgcagttg aagttaaaaa
     6841 cggcaagaaa aagctgggca gcgcaaaagc cggaaaagac ggcaaattca aagttaatat
     6901 tccaacccag aaaaaagatc aagtattgca tatcaatgcc tcattgggtg atgcaaaaac
     6961 gtctgtcaaa acagttgtgg taaaaggcaa accatcaggc gctccaaaag taaatggagt
     7021 gaaagcgaaa gacacggcag taaaaggaaa agcaaacagt aaggcagcaa tcaaggtcaa
     7081 aaataaatcg aaaaaggtca tagcctctgc gaaagcggat aataaaggag cgttttctgt
     7141 aaaaatcaaa aaacaaaaag cgggaaccgt cctttatgtc acggcggccg atacagataa
     7201 aaaagaaagc aaagcggtaa aagtggttgt ggaaaaatag aaaaaacagg cggagcctcg
     7261 gcggccgcct gtttttttat tcagttccgt cccgctgaac agcggagtac ataatggatc
     7321 gtttcccatc cgacgctgtc cattcaaacc ggtcgtttga ggaggaccct ctgctgtaat
     7381 gatgctgcaa ggcgcactga gcttcatcat ttgaaaaatg ataaaaggac acgccctctt
     7441 cttcttccgg actgccgcct gaaaataaac ctttattata agaaaaaaca cagtcaaata
     7501 cagataagcc gaagacacgc aaatgctgta aaaacgcaag aaaggtctca tcatcaagcg
     7561 aatccaaaag agccattaac ggacgcttaa tcgacttttc atagcggatg ctttccccgc
     7621 cggaaagcgg aatacggcgt ccgtcacgga tcacggcaaa gctgtttgaa atgccggctt
     7681 tctcccatac tccgttaaac tgaatataaa cgggggtatt cggaaggctt tcggcaagca
     7741 gcatatcgcc ttcctcattt tcaatgacgc atatcccgtc ttctacgatg attgttccat
     7801 attcccattt tctttcttct gtaaataaat actgttttcg cttcatagaa tggggtaatc
     7861 tcctttttta tttcatcctc accgttcttt ccaattcagg cttgtctcat acaagtcttc
     7921 atgggacaaa tcaactataa gcctatagat gcataagcta agaaaggtgc tgaaggatac
     7981 gaatttgata ccgaaagaaa cgggattgga gctgatatta catgtgcggt attacgggtt
     8041 gggtcgattt taaaaagcag ctcgtccaag aaaaacaaac gatgaacaaa atgacagaca
     8101 ctctttccaa acgaggacct gatgatacaa acgtttgggg aaagcatcat gttttattcg
     8161 gacataaaag gcttgcggtt gtggacattg aaggcgggcg ccagccgatg gcttgtactt
     8221 ttcaaggaaa tacgtatacc atcatttaca atggcgaact gtataataca gaagatttac
     8281 gaaaagaact gcaggctcgc ggccatcggt tcaaacggac ttctgacacg gaggtcttgc
     8341 tgcacagcta tattgaatgg caggaagaat gcgttcatcg cctgaatggg atttttgcct
     8401 ttgccgtttg ggatgaaaaa cggaatcagt tatttgcggc gagggatcgg ctcggcgtga
     8461 agccgttttt ttatacggag aaaggttctt cgtttctatt tggctccgaa atcaaagcca
     8521 tactcgccca tcctgatgta ccggcccgcg tggacagaaa cgggcttgcc gagatatttg
     8581 ggctcggccc gtctagaacc cccggcatgg gtgtatttaa agggataaaa gaagttcgtc
     8641 ccgcacacgc actgaccttt acaaaagacg ggctgaatat gtggcgctat tggaatgtgg
     8701 aaagcaagaa acatacagac agctttggcg agactgtcgc aaacgtaagg tacttatttc
     8761 aagacgcggt gacacgacag ctcgtgtcgg atgtgccggt ctgtacgttc ttatccggcg
     8821 ggcttgattc aagcgccatc actgccattg cagcaggcca ttttgaaaaa gaaggaaaag
     8881 gcccgcttca tacttattcg attgattacg aggagaacga caaatttttt aaggcaagcg
     8941 cgtttcagcc gaacgacgat ggcccgtgga ttgaaaaaat gacagaagca ttcggcacac
     9001 agcatcacaa atgtgttatc agccaggcaa agcttgttga atatttggaa gaagctgtgt
     9061 atgtgagaga tttgccggga atggcggatg tcgattcttc tttactgtgg ttttgccggg
     9121 agatgaaaaa agactttgtc gtcggcctct ccggggagtg tgcggatgaa atattcggcg
     9181 ggtatccgtg gttccatact gctgatgcgg aggcgggatt tccgtggatg agatctacag
     9241 aagagcggat taccctgtta caagattcgt ggcaaaaaaa gctgaatctg agagaatacg
     9301 tgaatgccaa atatgaagaa accttggcgg aaacgccgtt attagacgga gaaaccgggg
     9361 aagataaagt gagaagacag cttttctatt tgaatatgct gtggtttatg acaaatctat
     9421 tggatcgcaa ggaccggatg agcatgggag caagccttga agtgcgggtt ccgtttgccg
     9481 accaccgcct tgtggagtat gtatggaata taccgtggga gtacaaaatg catgaccagc
     9541 gggaaaaggg gattttacgc aaagcgcttg aggggatttt accagacgag attttatacc
     9601 gcaaaaaaag cccttatccg aaaacccatc acccggaata cacaagagcg gtcagtgagt
     9661 ggctgaaaca acttctgagc cagaaggatt cggtgcttca cacgcttctg aacaaaaata
     9721 aaatggatca gctattagaa acagaaggtt catcctttca ggtgccttgg tttgggcagt
     9781 taatgaaggg gccgcagctg attgcgcatc ttgctcaaat ccatacatgg tttgaagcat
     9841 accgcattga tatagacgaa taaaattcat atgccggttc ctgataagga acggcatatg
     9901 ttttatagat aaaggacaag cttcggaata cgatgatatg tgacaaagcc gcaaaaacat
     9961 aatagacttg gagaagaatt ttggaaagga gtgaatacga atggctgata tcaaaagagc
    10021 ctatcagcaa tgtgaagaaa tcacaaaaac acatgccccg acatgttatc aagcatttac
    10081 gttccttccg ctgaaaagaa ggcaggcggc ctatgcggta tatgcttttt gccatacagc
    10141 tatcacgata gacgataaag acgagctgtc tgcattagaa agagatgcgg aacaatgtct
    10201 cgccggtaca tatgaagaga atcatttttt gtgggctgcg cttgccgatg ctttccggca
    10261 gtttgcgtta gaagcggaac cttttcggga gttcatcgcc ggtatccatg aaaataacga
    10321 aaaaacgaga tttgaaacgc tcgatgaatt gctcatgttt gcatatcaaa cgggaagcac
    10381 agccggattg atgcttttgc cgattctcac caaaagaaat aaagaaaaac ttcgccaggc
    10441 tgccgtatcc ctcggcttgg ctatccagct gacccgcatg ctgcgggatg ccggtaagga
    10501 ttatcgccgg aaaaagcgta tttgttttcc tcagcaggcg atgcggcaat tcggttatac
    10561 agaagatgat ttttgcaatg agacggttaa taaggccttc gtttcaacat gggagtatgt
    10621 cgcctttgaa gcggaagcgt atgccgagga atgcttcgac gcaatgtccc tctttcctcg
    10681 atattcccaa tcatcagtaa aagccgcagc ttctttatat aaagctgttt tagaaaaaat
    10741 cagagcggaa cattacgaag tttttaccaa gaatatgacg ctgacggaag aggaagcaga
    10801 cgccatcctg cagcagctat aaaaaaatcc cggctctctt tagagaccgg gatttatgcc
    10861 attccttttt gaatccaaat tcgggagcgc catcttctgt acattaaaat tcctctgacc
    10921 cattcatccg cgataaagga aatccaaacg ccggcaaggc cgaatcctaa atggatgccg
    10981 aaaaggtacg caagcggaag tccgatgccc cacattgaaa tcatcgccat gtagaccgga
    11041 aacttcgcat cacccgcagc acgcaaggag ttgatgatga tgacattaaa tgaacggccg
    11101 ggttcaagaa taatcgtcat gacaatcagc atgcttgctg ttgcgataat atcagggttc
    11161 tggctgaaga tgccgatgag ctgtttggaa aacagagaca tgataactga agttcccgca
    11221 gcgattccaa gcgcccaata caggcttttc atacagcggt cataggcatt gtcaaattgt
    11281 ttggcgccga tataacggcc gattaaaatc tgtgttcctt gactgatggc ggtcccaaac
    11341 agcaggataa acattgtgat gttttgtgtg tatacttttg tagtgagagc ctgtgcgccc
    11401 ataatggcga taaaataggt aatcaccatt tgtgaaatgt tgtaggaaag ctgctccccg
    11461 gcagaaggaa ttccgatttt cagcagcttg cgcaaatgct ctttatgcac gtgaaacact
    11521 tttttcaatg tcaacgttag gttgatgcgt ttattaacaa ttacgatcat agcaattaat
    11581 ccgatgacgc gggcgatgga tgttgacatg gccacgccgg ccacgccgag aacaggcaat
    11641 ccgaaaggcc cgaaaatgac aagaaagtta ccggcaatat ttaaaacgtt catgccgatg
    11701 gtgacaaaca ttgtatcttt tgtatagccg tagctcttta aaatcgcact gaacgtcatg
    11761 attaacgcct gaataaacga aaggcctccg acaacctgta aaaagatttt cgcatcgggc
    11821 atcaggtcat tggtcagccc catcatatgc agcatcggaa cggctgccat aaacacagcg
    11881 gcgctgatga cgagactgat aacaaagtta gccccgatgg atacgtaagc gacctctatc
    11941 gcttctttct tttgctttga acccaaaaat tgagaaataa tgatagtcgt tcctgtagcg
    12001 ataaagctga acatcacgat aattaaattc aaaatctggt tgctcacacc gaccgcagcc
    12061 acgctgttat cggaatattg actgagcatc agagtgtcgg cattccccat aaacatatat
    12121 aatgaaacct caataaatat cggccaagtc agcgaaaata atgagagttt ttgatcagca
    12181 ggttgtttca atgcagtttg acgtaagaca gcctgtttca tagcgctacc cctttctttt
    12241 aaaaaaatca acgttttaaa gtgtaccgcc atttccttat aataaaaagg gagagaaccg
    12301 aaacttcttg caataatccg acttaaaaag gaggatgaaa aaagtgccgc gcatcatgtt
    12361 tacagtgccg ccttttccgg tctttatcgc agccggtgaa ggtgttttta aaaaaggcga
    12421 aatgcatgcg agacgaattt tttccgtatt tgatcttatc tatgtaaaac aaggaacctt
    12481 atatataaca gaaaatgacc agaccttctc ggtgggagga ggcgaatata ttttgctgtc
    12541 gcccggcttg gagcatttcg gctcaagggg ctgtgaagaa aatacttcct attattggct
    12601 tcatttcgac gaaaaaaggt atgaattcac gcaaaaaggc ggaaacaatt gggcggagct
    12661 gctgcaggaa aaaggcagct ttgaagagcc ggcccgctat cgcctggcct tgcctcgcaa
    12721 aggaaaggtg cagcgtccgc tatttatgga aaaacaattt gacagcttaa tggattacac
    12781 tgctgaaaac tcggatttgc cgctgcgcaa gcaaatcctg ttcgaagagc ttttgctgca
    12841 tctccaaaaa gagtcatttc agattccgtc agctaaagag cgggtcgcat gggacgccgc
    12901 cagatacttg caagagcatt ataaagagcg ggtgacgata aaggacctct cttacgcgct
    12961 ccactatcat caggattacg tgacccgctg tatgcagcaa gtgctcggag taactccggg
    13021 ccaatataca aacaaggtga gaatgacaga ggcgaagcgc ctgctgtctt caacaaatga
    13081 caaaatgggg gttatcgcgg aaaccatcgg aatggaggac ccgacttatt tttcaaagct
    13141 cttcaaacag actgaaggcg tgtcaccgat tgaataccgt aaaatcgtaa gccggaaaat
    13201 cgagtagtta tttttcaata tttgacaata aagtgaatgt tttatagaaa cgtttcgtat
    13261 gtacaccttc tcttggtagg atagaatagg gcggtttcta ttcgtctgaa agataagagg
    13321 aggtgctgat ttgtggataa acctgaagcg gttttcggtt ttgagcaaaa ccgggtcaca
    13381 attaaagatt atatcaagct tgtaaaaccg ggaattatta tatcaaactc aattgccgca
    13441 ttcggcgggt tttggatcgc ttatgtgagt tcagaaaaag ctttaacagg ctccgcgttt
    13501 tttgtgacca tgctggcggc tatgatcgga acggcgtttg ttatggcctc aggcacagta
    13561 tataacaatt attttgacag aaagattgat gccaaaatgg cccgtacacg tcatcgggca
    13621 tctgtcactg ggaaaatgtc tgcggcctcg attatcactt ttggtacatt cttaggaata
    13681 gccggactgg ggatgctggc ggccctgaat gtgttaaccg ctgttttagg ttttttagct
    13741 tttattttct atgccgtgat ttatacgatc tggtttaaaa gaacgtccgt ctggagcacg
    13801 gttgtgggga gttttccggg agccgcgccg ccattgatgg gatattgcgc tgtggcggga
    13861 catatagaca tgacagcagt tgtactgtac gccattatgt tcttatggca gccacctcat
    13921 ttttgggcaa tcggcatcag gcgaaaagaa gagtatcgag cggcaggcgt cccgctattg
    13981 ccagttgtaa aaggtaatca tgtcacaaaa ataagcatac accggtatat tacagtgctt
    14041 gttcccgtta cacttttgct ttccttttat gtcggccttc atcatttgag cccgctctat
    14101 tttatttctg ccttaatcct cggattcata tggatatata aaagctatca gggatttaaa
    14161 acggatgatg atgttcaatg gtcaaagggg atgtttatct attctctttt ttatttttgt
    14221 atattgtttt tcattatgat gatcgactct ttcgtcatgg ctttttttgt acaatgataa
    14281 acgatgcctc atatcctgga cctgtccacc ttccgcagcc ctgttctttt ctgataaaat
    14341 aatgaaacac gaaaatggtg aaggaacgga tgagggattt atgatgaaaa aaacaattta
    14401 tgacgtggca aaagcggcag gcgtctccat tacaacagta tcgcgtgtca ttaacaatac
    14461 cggcagaatc agcgtgaaaa cccggcagaa ggtgatgcgt gtcatgaaag aaatggatta
    14521 tctgcctaat gtgcacgcct ccgcgctgac aggaaaacgc tcgaatatta tcggcctgct
    14581 gactccggat atatcgaacc ccttttttgg cgagctggca aaaagcattg aagacagggc
    14641 agacgagctt gggttcaata tcattatttg cagcacggat catgattcga aaaaagaatc
    14701 gaaatacttc tcaattctca agcaaaaaag cgtggacggt atcatttttg ccacaggaat
    14761 tgagaatcat gacagtatgt ccgcattaga agatatcgtc aatgatgaaa tcccgcttgc
    14821 catgatttct caagataaac cgctcgttcc gatggacatc gtcattatcg acgattttct
    14881 cggcggctat gcggcaacga accatttgct gtccttgggc catagaaaaa tcgcctgcat
    14941 catgggggac ggctccacaa caggtgaaaa agacaggatg aaaggatttc ggcaggccat
    15001 gcaggaggcg gacgtgccga ttgatgattc gctctttgtc ccgacagtat tttcattgaa
    15061 aagcgggaaa gaagaagcgg gcaaattgtt tgaccgaagc atgccgaccg ccatttttgc
    15121 atttaacgac gttttggcgt gcgcggcgat tcaggcggcg agagaaaggg gaatcaaggt
    15181 gccggaggat ctgtccatca tcggattcga caataccgtt cttgcagaaa tggtcgatcc
    15241 gccgctcacc acgatgtctc agccgattcc tgaaatgggc cgccgagtcg tcgaactgct
    15301 tgttgatgaa atgaaaggaa agaaaacggc aaaacaaaaa atcatgttgc cacccgagct
    15361 tgtcattaga cattctaccg ctagattaaa agacattccg ccagtccggc tttcatagcg
    15421 gtcttttttt tttgtgaaaa tgaatgtgtg aaaaaacaaa aaacatattg cgaatgggaa
    15481 aaaggcattg tagaatgaaa tcacctcgtt gagaaagcgc ttgcgcaaaa ttaagaaaac
    15541 cgttaagcgg tcagtggatg ctgaaacggc actttatttc acctattatg taaagcgctt
    15601 tcattaaggg tgatcccgga cggaatcatc acatgtaaag gcttcggcgg ccgggtcaga
    15661 caacataagg agttgattgg caatgacgaa tcaagtaaga tgcgcagtat tggggctagg
    15721 gagacttggt tactatcatg caagaaacat catcaacgaa gtacgcggag caaagctcgt
    15781 cagcgtgtgt gaccctatga agggaagggc cgagcaggtc gccgaagagt tcggcttgga
    15841 aaaatggacg gataatccgg atgtgatttt ggaagatcct aatattgacg ccgttatcat
    15901 tgtcaccccg acaagcaccc atgcagagat gatcaaaaaa gctgcggaac acggcaagca
    15961 aatcttcgtt gagaagccgt tgacgctgaa ccttgaagaa tcaaaagaag tgatagaaaa
    16021 ggtaaaagaa acaagcgtca tctgccaggt cggctttatg aggcgattcg atcccgcata
    16081 tgcagatgca aaaaggcgca tagacgccgg agaaatcggc aagcccattt actttaaagg
    16141 ctttacgagg gacagcggtt caccccctcc ggagtttatc aaacacagcg gcggaatttt
    16201 tatcgactgc tcgatacacg actacgatat tgctcgttat gtgatgggag ccgaaatcac
    16261 ctctgtttcc ggacatggcc ggattttgaa caatccgttt atggaagcgt acggtgacgt
    16321 tgatcaagcg ttaacctatc ttgagtttga ttcaggtgcg gccggtgatg ttgaagcaag
    16381 caggacctcc ccttacggcc atgatatccg agcggaaatt atcgggacag aaggcagtat
    16441 atttgttgga acattgcgaa atcagaatgt gacgatccta acgtcagcag gcagcaacta
    16501 tgagatcata ccagactttc aaactcgttt tcacgaggca tattgtttag aactccagca
    16561 ttttgctgaa tgcgttcaaa caggaaaacg tccgcttgtc accgagatcg acgcaacgat
    16621 caatttagaa atcggaattg cagcaaccga ctcatacaaa accggcaaac ctgtaaagat
    16681 tcacatggat aaaattcacg cggatgtgta acacgccaaa gcgcccttgc agcaggatga
    16741 tggcggcttt gaaagatgga agagaaagtg ggaaatgatt caaacgaagg catcacgctt
    16801 ggaattgctc cgttcagctg ggcgaacgac gaccttccgg atcgagacgc gaccagttgg
    16861 aagtattgaa aacctatttt aatagaatca gatatgtgca tgtaaaggac gtaagaaagg
    16921 acattttttt atgaggtttc agaaaaaaat ctggatttcc ggcaggctgt ccgtaaaggg
    16981 ttttacggtg ccggggacgg agattttgat gttgcgccca ttgtgaaata gctggcggaa
    17041 aaggcggtac agcggctggg ccatcgttga agcggaacag agcccggcga tctatgatcc
    17101 ttatgattat gctaaacgtg caaaaacata tatgggcggt ttgcttgttc gtgaacgaaa
    17161 cagatagagg catctctttt acgggctgac agtcgaaaag attgccagcc gcttgtctta
    17221 ctgcttcaat ccatacaaat attggatata gtcagttgca attcctttat gtcccagctg
    17281 ccgcagcatc gccgttatat tcccgcgatg atacgtaccg tggttgataa tatgctgcat
    17341 gatttctgcg tatgtggtgt caagcgtgcc gtagtgctga tgataaatgg aaaaaggctg
    17401 gtccaagttt ttttggcggg tgaaaaaatc tctatattgc ccgtttaagg atagaaactg
    17461 attttcaatc gcttcgagct gcccccgaat accttgaaat tggctcagat cgtcaatagc
    17521 gtcttgaaaa gaatctccta acagcgttct gagccatata taatctgttt ggcacatgtg
    17581 aaacagcact tcatttatgg aagaaaaaac actcttcgtt tcttgattgg caatgtcggc
    17641 cggcaggctt tttacgtgtt caacaatccg tttgtttgcc catgtgtgat actgataaag
    17701 ctgttctata ttattcatct gactccccct cacttttatt attctctttt ttattcggca
    17761 attccttttt ttaaaacagc agtgcagccc cccgcatcac caaagctgaa catttattta
    17821 atacatcatc agtcctccgc ccgtatccag cgttttaaat attcgcacag ccaaaaccag
    17881 cacgataaac cagacccaag aaacggcaat gcaagacagc gtatataacc atttatcaag
    17941 tcccgtgtac ggaagcgatt gggtgccgat cacaccggca gtgtccaaaa tggcgtgcgg
    18001 atttaagagg gaaaccgctg ccgcaaatgc ggcttgtttt ttagcgctga acacgttctt
    18061 ttgcgtctca tccggatccg gccgtctgtg ccatgtcacc cagcccatat aagcaagaaa
    18121 caaaaatctg gacgtaagca tgatcgtttc aaagacggga atctgctgca caacaacaac
    18181 atgccgggac tgtgctttca aaacagcaga gacaagaaat gattcggctg acaacaaacg
    18241 agcggatgcc aatcatagag gacgaagcgt acggagattt gtggtttgaa gaaaagccgc
    18301 cgcccccaat aaagtcgatg gataaggaag gaaatgtcct gtatctgggc acgttatcca
    18361 agacggtgag tccgggactt cgcatcggct gggtgaccgg acctgaaccg gtgattgaga
    18421 ggctggctga tatcaaaatg cagacagatt acggttcaag cgctttgtcc cagtgggctg
    18481 cggcaaagtg gctgtcagaa ggccgttatg aagagcatct tgcgtggctg aggaaagagc
    18541 tgaaagacag aagagatgca acactccatt ttctgcagcg atatgcggga gatatcgccc
    18601 gatggaacgt tcccgcaggc agtttctata tttgggtgac gtttcatcag ccgctccctt
    18661 tcagacggtt atttaaccag gcgctgacaa aaaacgttct cctgaatccc ggttcagtat
    18721 atgatccaga tgaccggcaa agcttgcggc tgtcttattc atacgccgcc cttcctgata
    18781 tcgggaaggg cattaaggta ttagcagaaa cggcgcggca attgatgtcc gagcacacga
    18841 aataaaaagg gggctcttat ttaatgaccg cgccgagtgc tctggcgaat acggtggcct
    18901 gttgcggagt tattttacag cctttcagct tttcaagtga aacatgaatc tgttcaaacc
    18961 ggcagctgct gatgtccatt ttttgaagag acgtcccgat aaagtttgcg ccctccaagt
    19021 cacacgaatc aaaatgtgtg tgctgcaaga cagcgtcatt gcattcacat tgcaaaagtg
    19081 aacattgatc aaaacgaacc tgcttcatat tagaaaaaag gaacgaactg aaattggcgg
    19141 ggcactggct gaacaaaaca ttccgcatgg ttgcttctgc caaattgatt cctagtagct
    19201 ttgactgtct ccattcggtt ctgtggataa tagcgccgct aaaatcggca tttgacagat
    19261 cgcacttttc aaacagcaca tcggttaatt caatattccg gaatgagaca tcaataaatt
    19321 gcacatttct gaaaaccacc tgatctgcgc atattctttc aatgtcttcc ccaatgatcg
    19381 aacaatcttc aatcaggcac atctcgagtt gatcatcttt cgtcagcccc tcgccgaagc
    19441 tggctgctgt aagggtttcc ggaattcggg gtttttgaat ggtgcttgta ttcatctgat
    19501 gacatccttt actgatcttg cggaaagata ctccgctgag acattttttt agagtttgat
    19561 aataaattgc aaagctgtgc gatacatata gttaaatgag tgccttttaa agctggtgaa
    19621 gttaaccgca gcagccatgc agctggaagc ggccattaaa acaggaactc caagcaggct
    19681 gaatacagag cgaagtttta taatgataaa gctttgactg ttcaaccggc cgaaaatatc
    19741 agcatgttta ctgtgtttaa tggcggttcg tcccgcttat ttctaaaagc ataatgggaa
    19801 ggtcctttca cgtcaagggg cggcggatga tcactgggga acaagacagg aggttttaaa
    19861 atggggcatt acattcaaac ggaagagcat gtgacgctat ttgtggaaga tatcggttcg
    19921 ggccggccga ttgtcttttt gcatggctgg ccgttgaatc accagatgta tgagtatcaa
    19981 atgaatgagc tgcctaaaag aggcttccgt tttatcggca tcgactttag aggctacgga
    20041 aaatctgacc gcccgtggac cggctatgat tatgacacga tggcagatga tgtaaaggct
    20101 gtcatataca ccttgcagct tgaagatgcc gtgctcgccg gattttcaat ggggggagcc
    20161 atcgccatcc gttacatgtc gaggcacgac gaagcagata ttaagaagct gattctaatg
    20221 ggagccgcgg cgcctgcgtt tacaaagcgg ccgtattacc cgtatggctt cttgaaaaaa
    20281 gacgtcgacg acttgattgt ccaattcaga aatgaccgac cgaaagcact tgcagatttc
    20341 gggcaattat tttttgaaaa gcatatctcg ccggaattca ggcaatggtt tcaggagctg
    20401 aatctgaatg cttcccccta tggcacgatt cattccgcta tagctttaag agatgaggat
    20461 ttaagaaaag agctcggaga cattaaggtg ccgactctca ttatgcacgg cgtcaaggat
    20521 aaggtatgtc cgtttgattt cgccagagaa atgaagcgcg gcatcaaaca agccaaatta
    20581 attccgtttg aagaaagcgg ccatgggctc ttttttgacg agaaagaaaa attaaataat
    20641 gaaatcatgc ggttttcaag gtgaagcgcg aaaaaacccg atgtaagaat tcgggttctt
    20701 tttacacgtt tatatgattc ctttagtatg cagttcatga atgatcaagt ctgctgcatc
    20761 cgcaatggat attttatctg attcaatcgt cagatcaggc gaaagcgggg cttcataagg
    20821 ag
//
