LOCUS       NZ_JAHWJB010000003     47599 bp    DNA     linear   CON 12-SEP-2024
DEFINITION  Bacillus sp. FDAARGOS_1420 tig00000008_trim_arrow_pilon, whole
            genome shotgun sequence.
ACCESSION   NZ_JAHWJB010000003
VERSION     NZ_JAHWJB010000003.1
KEYWORDS    WGS; RefSeq.
SOURCE      Bacillus sp. FDAARGOS_1420
  ORGANISM  Bacillus sp. FDAARGOS_1420
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
REFERENCE   1  (bases 1 to 506737)
  AUTHORS   Sproer,C., Gronow,S., Severitt,S., Schroder,I., Tallon,L.,
            Sadzewicz,L., Zhao,X., Boylan,J., Ott,S., Bowen,H., Vavikolanu,K.,
            Mehta,A., Aluvathingal,J., Nadendla,S., Lowell,S., Myers,T. and
            Yan,Y.
  TITLE     FDA dAtabase for Regulatory Grade micrObial Sequences (FDA-ARGOS):
            Supporting development and validation of Infectious Disease Dx tests
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 506737)
  AUTHORS   Sproer,C., Gronow,S., Severitt,S., Schroder,I., Tallon,L.,
            Sadzewicz,L., Zhao,X., Boylan,J., Ott,S., Bowen,H., Vavikolanu,K.,
            Mehta,A., Aluvathingal,J., Nadendla,S., Lowell,S., Myers,T. and
            Yan,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (17-JUN-2021) Center for Devices and Radiological Health,
            US Food and Drug Administration, 10903 New Hampshire Avenue, White
            Oak, MD 20903, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: canu v. 2.1.1
            Genome Coverage                   :: 1241.19x
            Sequencing Technology             :: Pacbio; Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_019344915.1-RS_2024_09_12
            Annotation Date                   :: 09/12/2024 05:20:37
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,050
            CDSs (total)                      :: 6,900
            Genes (coding)                    :: 6,426
            CDSs (with protein)               :: 6,426
            Genes (RNA)                       :: 150
            rRNAs                             :: 12, 12, 12 (5S, 16S, 23S)
            complete rRNAs                    :: 12, 12, 12 (5S, 16S, 23S)
            tRNAs                             :: 109
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 474
            CDSs (without protein)            :: 474
            Pseudo Genes (ambiguous residues) :: 0 of 474
            Pseudo Genes (frameshifted)       :: 199 of 474
            Pseudo Genes (incomplete)         :: 296 of 474
            Pseudo Genes (internal stop)      :: 116 of 474
            Pseudo Genes (multiple problems)  :: 119 of 474
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 23:39:16
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 150038
            Orig. end                         :: 197637
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JAHWJB010000003.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..47599
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="NRPS"
                     /region_number="2"
                     /rules="cds(Condensation and (AMP-binding or A-OX) and not
                     alpha_am_amid)"
                     /tool="antismash"
     cand_cluster    1..47599
                     /SMILES="NC(CC(C)C)C(=O)NC(Cc1ccc(O)cc1)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX) and not alpha_am_amid)"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..47599
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="False"
                     /core_location="[20000:27599](+)"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      20001..27599
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     gene            49..936
                     /locus_tag="I6L50_RS29810"
                     /old_locus_tag="I6L50_29790"
     CDS             49..936
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="I6L50_RS29810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="I6L50_29790"
                     /product="hypothetical protein"
                     /protein_id="WP_219303854.1"
                     /transl_table=11
                     /translation="MIKLSLLENAYDSIQNGVEYLESAVKTENIYDYKHAVLNLCQGTE
                     LLLKEILFLKNPIYAFDKNSLFNKCENPLDPTLEELYECKSLDVNSLCYAVAKYAPDFS
                     GNEKVNLKIYEKRASKLRNKVQHFCFAIKSEEVREIVLKLYHQVIAPALLYINKQPDHT
                     FEEKLGNIFCSDERRERHEMMLNLQKEDYAIGNCFSCGHYSFFIMYRGNSYPTDCYCTT
                     CSFTIESIIDSDYLECPECGINSLVYNHELEAGTCLNYRCANHRDGGVLVDMEYCSSCR
                     EYRIEDTCQCEEEE"
     gene            972..1181
                     /locus_tag="I6L50_RS29815"
                     /old_locus_tag="I6L50_29795"
     CDS             972..1181
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="I6L50_RS29815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="I6L50_29795"
                     /product="hypothetical protein"
                     /protein_id="WP_219303855.1"
                     /transl_table=11
                     /translation="MNNKLDRFEMDYWIYMLGVGWKSEIECTLNNRKSPYKTNISIREK
                     LSFLVEAFPELKENRDFYDWILSD"
     gene            1764..2441
                     /locus_tag="I6L50_RS29820"
                     /old_locus_tag="I6L50_29800"
     CDS             1764..2441
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="I6L50_RS29820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="I6L50_29800"
                     /product="hypothetical protein"
                     /protein_id="WP_219303856.1"
                     /transl_table=11
                     /translation="MSDVLVDFSEEIRIYKDRIRIFLILYFLSEDMSEEHGNNTLKKVF
                     KSEVKIQKVDFLVRNPDYFAYQILLFAQENKISKQECKEIVKNIFTQREPSIRRLEMEK
                     FFFGAYENIDDVISFLKSIGFIDFNSKKSLDLRTIEKHYYITELACRKIDEIQNLKSLY
                     WYKERIELIKRFFGDLGGTQLKDLQYEIDEYKDASYKECISNIQDRVKKIYLEMFGEEL
                     YEI"
     gene            2431..4503
                     /locus_tag="I6L50_RS29825"
                     /old_locus_tag="I6L50_29805"
     CDS             2431..4503
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="I6L50_RS29825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="I6L50_29805"
                     /product="hypothetical protein"
                     /protein_id="WP_219303857.1"
                     /transl_table=11
                     /translation="MKFNFERFVEEVHKAYSDTFTLREVNELLNTVYEYKKDTPISTGK
                     KLILTKINIIGIKSSGEEINFSLPLNTGVNIIVGDNLKGKSSLFKMIQLALTGSNKLKH
                     DVKKWIKSILLSFKINDKQYSIIIKFENNRMKGALYSGVIDNIDDRKISKLDPIFETST
                     INEYEEQIQDFFFMQFSYYSLKWTQKSSSKEKNELVEANASWKTYFKSIYLESKDSASL
                     MYGSQGKKVFQMLLGLELTLVINQLSVKKDFLQFNNAKQIDQTQGQKNQDKKDYLLQRK
                     VDLENELVELNSFKMDSINQLHEKYEIIVNEINDENALITKNTIELSEERKLISEINWE
                     LDTYTNELKRIKKEINKNDRAINDMKEYIEIGIFFSNLNIKQCPSCNHEVKKENIHQEK
                     KCVLCHEPVHDLDKEINQDIYYQKLADLEIIKKKLNEEKSLIEKKIIKFNREFEQKSLI
                     IKQLEDPVINREKISSLKKKLKDIEESINKEMEKLSPKNERKTVLVAEKAVIDYRLDKL
                     TQSPDSLYKEEKKIELLEKAIRKLNKLRYDNGQKILKYLSDLMLENLHHFGLNSITEIK
                     INENFDIKYKQNGYDLTFDSIAEGEQLRAKIALYLALIQLDIEYNFGRHTRFLIIDSPN
                     KEEGDSNYLTGLTEVLVDIDKRYGDNLQIIIGTAERKLAHIVQNEKVFNKGEYVF"
     gene            4503..6197
                     /locus_tag="I6L50_RS29830"
                     /old_locus_tag="I6L50_29810"
     CDS             4503..6197
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="I6L50_RS29830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="I6L50_29810"
                     /product="hypothetical protein"
                     /protein_id="WP_219303858.1"
                     /transl_table=11
                     /translation="MKECIEIENFQNMKIHEKIYFFDIKSPDILINFDGKKVQQFLKNI
                     ILDSGENLYIRKKALENFINLVMIKKIKKRSALGILIDEWEFTGDDFLEITRLKKLFLF
                     YEDETEEIEEIYIVLKEHEKNEIKSESLFQLGCIYFLKANAIKDKEAYVKCLKSSLEYF
                     QKSNNCIENRIDAEFFCTVIKLLLDIIQHRESEFQLSFKKMAKLLWQQKLFSFESQVAP
                     LQVGLFRTLNAFRKISMVEPSSWLDYRKEFNQLCYYFYEIKNQEVCMELMESSLLKNMK
                     GNLMRRTIEPLFSLNFKAEICKIEKLLNEADKESEMHKFLSYLKQLISKTEVKENAEKD
                     IIFSKIINAFPNIDNSRIKKEFQKITGDINTHKILNLLELFSEYSYDKLIDVIINACIN
                     LQGNQLYRDKTENERNTFLATCLDMAGFYNKDQTLWSKSNEGKTSGEIDIFVKKKNGLP
                     FSIIEALNLDSLKKDYLELHLRKIFGYDTTGLKYNFIIVYSSSKNFSGLWKRYVDHIKK
                     YKYPYAKIDYKEVEEYVYANIKVGKTVHLRNNQEIYLVHIMVDLSLF"
     gene            7004..7165
                     /locus_tag="I6L50_RS29835"
                     /old_locus_tag="I6L50_29815"
     CDS             7004..7165
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="I6L50_RS29835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="I6L50_29815"
                     /product="hypothetical protein"
                     /protein_id="WP_219303859.1"
                     /transl_table=11
                     /translation="MGRVSKLRESDYLLQYINVKYHKWIKFAVEPRDIITYYGDLGINF
                     NFNSIAST"
     gene            7736..9181
                     /locus_tag="I6L50_RS29840"
                     /old_locus_tag="I6L50_29820"
     CDS             7736..9181
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002035166.1"
                     /locus_tag="I6L50_RS29840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I6L50_29820"
                     /product="3'-5' exonuclease"
                     /protein_id="WP_257475432.1"
                     /transl_table=11
                     /translation="MSLLVLPAPEGRQKEVLCLPEIGHYVVLGTAGSGKTTLAIHRAAY
                     LAKRSKSKEKVLLVTFNKSLVTYLNSLAENNLYNVDVRNYHRFARGYLDHKGMLGWNDI
                     VPSMDYNRENKKLSFIKQSLNEVIEEHGNNSTLSRAPEVFYEEISWIQKMGISSLEEYI
                     DAERIGRSGTRITRDKRHYFFAVYERYLDIRGRNDYRYDWDDLAHTVISELENDDDNDK
                     MYKHIIIDEGQDLSPVMLQSLALAVPKDGSITFFGDVAQQIYGGRLSWRNAGLNVTRNE
                     IWKFDQNYRNSKEIADLAIAISKQPFFNQNTDLVTPIEPVASGPQPVLAEFQNEATELK
                     WVIRNAVTLGERQTVAILMRTRESLKKVRALLGEVGVSPQELDGDLKRWKNNPGVSIGT
                     YHSAKGLEFNAVMIPYCSADRLPDQDKITALEDRDEALGEESKLIYVAATRAKRVLAIS
                     YTGVVTEIIPQDDSLYSKRKIEK"
     gene            9192..9878
                     /locus_tag="I6L50_RS29845"
                     /old_locus_tag="I6L50_29825"
     CDS             9192..9878
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025840.5"
                     /locus_tag="I6L50_RS29845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I6L50_29825"
                     /product="DarT ssDNA thymidine ADP-ribosyltransferase
                     family protein"
                     /protein_id="WP_219303860.1"
                     /transl_table=11
                     /translation="MDELLIRQEYQKRNITRLCHITRSQKAVHILSSEDGIQAVEFLDK
                     SLYDANDELRLDGRKDFINCSIQYPNHWYWKRVKDKDPLFREWVILLINPEILTLDTTE
                     FCPVNAATKRGAYINSGYSGFKELFNERVNYRNRPSQMLHCCPTDDQAEVLVYKNISRK
                     DIIGVVVLNEDQGEGESVRWEMLNIPKFDISIAPDLFDGEWSTKVRKGIRPIEYNYQGG
                     ASLGKE"
     gene            9865..11532
                     /locus_tag="I6L50_RS29850"
                     /old_locus_tag="I6L50_29830"
     CDS             9865..11532
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF015692.5"
                     /locus_tag="I6L50_RS29850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I6L50_29830"
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="WP_219303861.1"
                     /transl_table=11
                     /translation="MEKSENQKLDKWLGALVGAAAGDALGWPNEQNSKNISKAPHKEQE
                     IFQKWERRDGGRFWSHYEEIHPGEYSDDTQLIIATARSLSHGSNWNKLFSKVELPAWIS
                     YERGGGGATKRAAETWRKGSNPWNVEKESKEDVQRYFSAGGNGVAMRILPHVFRREGAW
                     AEVKHQVFLNGIFTHGHPRALIGALVYADALTYLQNIEKTLGYGELVDYLLERREEWGS
                     FPNVQKLDSWMNAANLVFKDNYMGLWDEVTEEVLEQLKIIKEGLDQGALDIGDEVLKKL
                     GCFDKKVNGSGTVTAVASIYLASKYASSPRLAIIEAAYLKNADTDTLASMVGGLLGILH
                     GSEFLSVSWLDVQDYEYLKSLIHQENKEDTKLNGPLFDYYNPEMKAKFKHLQVGDILRA
                     EPFGRLMLKDKHINRPNAKNAIVNTLKFVTEEGQHIFVKTYEKGSVEDEYPLKDSKCNM
                     LVNQSISRYQQQQTRPSGYPDKPVLDSRKIRGLSNILPEKLEFDLCLQFIADIMDEIER
                     NGSGGINQNGLKFLEQRWMKHQIDMKDIEKAVNVILKY"
     gene            11728..13050
                     /locus_tag="I6L50_RS29855"
                     /old_locus_tag="I6L50_29835"
                     /pseudo=""
     CDS             11728..13050
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001055915.1"
                     /locus_tag="I6L50_RS29855"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="I6L50_29835"
                     /product="IS4 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MNIHQKQGLSIFAEELYRYMSPATLNQLAIEAGGVKRKRKCHGQY
                     FLSLCVWLNQQIATTSLTRLCSQLETSTGVLLSPEGLTRHFNSASVTFLRTLFPTLLQD
                     KIGGLSKIFHSLSAYFERMRIHDSTTFQVPD"
     gene            <13250..13387
                     /locus_tag="I6L50_RS35100"
                     /pseudo=""
     CDS             <13250..13387
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002170924.1"
                     /locus_tag="I6L50_RS35100"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="site-specific integrase"
                     /pseudo=""
                     /transl_table=11
                     /translation="LLLAKGVNVISE"
     gene            complement(13777..14100)
                     /locus_tag="I6L50_RS29860"
                     /old_locus_tag="I6L50_29840"
     CDS             complement(13777..14100)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1148: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000468116.1"
                     /locus_tag="I6L50_RS29860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I6L50_29840"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_219303862.1"
                     /transl_table=11
                     /translation="MFGTRLHTLRKECKLRQEDMAKQLGIARTTYAMYEQGNREPDYDT
                     LIKLATFFEVSIDYLLGTTEIRKATDIQDPELYQWFKDINNATPQKREELKKFWEFIIQ
                     RED"
     gene            14261..14449
                     /locus_tag="I6L50_RS29865"
                     /old_locus_tag="I6L50_29845"
     CDS             14261..14449
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001213249.1"
                     /locus_tag="I6L50_RS29865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I6L50_29845"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_219303863.1"
                     /transl_table=11
                     /translation="MRFWLLEKRKNKEKTQDYIAYKARISRSMYAMIESGERNPSVPVA
                     KNIARALNFDWTLFFEE"
     misc_feature    14451..14464
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 18.15"
                     /tool="antismash"
     gene            14566..14976
                     /locus_tag="I6L50_RS29870"
                     /old_locus_tag="I6L50_29850"
     CDS             14566..14976
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001056451.1"
                     /locus_tag="I6L50_RS29870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I6L50_29850"
                     /product="hypothetical protein"
                     /protein_id="WP_219303864.1"
                     /transl_table=11
                     /translation="MNMKTFEMREKRLAELLGAKVLWEFISAVTEEIEKQELESTPGLL
                     EDLFIHVKETIQIQNMNQRITKASVKTEADGINKDTLFMEAYVELINHKFIISELAVEL
                     SSVLKELNYFVQSSLPQLQSELDSQEPQSASL"
     gene            complement(15820..16464)
                     /locus_tag="I6L50_RS29875"
                     /old_locus_tag="I6L50_29855"
     CDS             complement(15820..16464)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016135835.1"
                     /locus_tag="I6L50_RS29875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I6L50_29855"
                     /product="hypothetical protein"
                     /protein_id="WP_098618353.1"
                     /transl_table=11
                     /translation="MNIELLDTHHVKDAAHLLAHSFVNNEPLVSSLQIPFAPFHKMCEE
                     MIKQAVSQAMSFVAIDNFQIVGVLLTRKVTQPLIDKDKANELCPQMDPIFQLLDTLETE
                     SIEFSHLDKEKLVYLDMGACHPDWMGSGIVTSLLSHAIQEISKKDFDFIAACTNKISQK
                     ILNKLFTTLEMNEIVYSNFSYKETYPFANTTTSLAAQLLYIPQSQFVIKAI"
     gene            complement(16569..18221)
                     /locus_tag="I6L50_RS29880"
                     /old_locus_tag="I6L50_29860"
     CDS             complement(16569..18221)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1180: Decarboxylase, pyridoxal-dependent"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001152301.1"
                     /locus_tag="I6L50_RS29880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I6L50_29860"
                     /product="pyridoxal-dependent decarboxylase"
                     /protein_id="WP_219303865.1"
                     /transl_table=11
                     /translation="MQDILKLFPSVDGNEEKQQLLLESMQKIIKNLDQLKNEERATLGK
                     CEEKSEGYYNSLIHQSHIPLAGITMSEVIEELNQFMNGHPYPNKYYLSNAVPLPSIPSL
                     LGILTMALLNGNGVWDVYGPGAAEAEVKVVSMLSKLIGYNPHNSGGYTTWGGQGCVFSS
                     LRLAISKQFPLAKEHGAPQNVYCFASENAHYSLLKSAEATGIGSNHLIKVKTDPYTNSM
                     DIEDLEAKMIQVIKNGGIPLYILATMGSTDTFTIDDIKKIKESAEVIQKIYKLKPIYIH
                     ADSAMGGFYSFFNNYSFEENSLSFEPNVKNALQYVQDKMQYMSLADSVCFDFHKLGQTP
                     YASSILIVKNHTDLQLMDIEQDDTPYLGNRSYGSYHTGYTLECSRAGSAIPMYINLLAF
                     GIEGYQKLLANYVRVNLLFREKLREALPQVAITNDFTYGPITTFRFYMNGDGQENWEKE
                     RIGLATKEEIEDTNRLNIELFNYLGKNRDQVFFGDTTRSCVVDVINSSDRNPISTLKFF
                     SISPYTTVECLDDIVSFLYEHISIATKQTYSYV"
     gene            complement(18706..19632)
                     /locus_tag="I6L50_RS29885"
                     /old_locus_tag="I6L50_29865"
     CDS             complement(18706..19632)
                     /EC_number="1.1.1.-"
                     /GO_function="GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1039: aldo/keto reductase family oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016090563.1"
                     /locus_tag="I6L50_RS29885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I6L50_29865"
                     /product="aldo/keto reductase"
                     /protein_id="WP_219303866.1"
                     /transl_table=11
                     /translation="MEYRLLGNTGLIVSEIGFGSWAIGEDEWGAVKDNESIDAINKAID
                     LGVNFIDIADVYGLGHSETLVAKAINNRRQDIILSTKGGLIGHHYDQNQPAVFGDPQKI
                     IDAFEASLLRLKTDYIDVYFCHIWWDKPEETEAFLQAFQTLKTSGKVRAVGVSTNDLDY
                     IKHFNQNDDLDVVQFDYSILNKEPEKDILPYIEKHNLGAVIRGPLKMGILTGKFNHETQ
                     FPEDDLRKDWPKEQWFKDSLNKIEKLGSLVRSNRSLAQIALRYVLSHPAVSVAIPGAKN
                     STQVEENSLHLTRPLLLNSENEFIKKL"
     misc_feature    complement(19883..19898)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: medium, score: 23.21"
                     /tool="antismash"
     gene            20001..27599
                     /locus_tag="I6L50_RS29890"
                     /old_locus_tag="I6L50_29870"
     CDS             20001..27599
                     /NRPS_PKS="Domain: Condensation_LCL (13-310). E-value:
                     1.5e-58. Score: 190.1. Matches aSDomain:
                     nrpspksdomains_I6L50_RS29890_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (477-877). E-value:
                     4.9e-104. Score: 340.1. Matches aSDomain:
                     nrpspksdomains_I6L50_RS29890_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (984-1054). E-value: 1.5e-21. Score:
                     68.3. Matches aSDomain: nrpspksdomains_I6L50_RS29890_PCP.1"
                     /NRPS_PKS="Domain: Condensation_LCL (1075-1376). E-value:
                     2.6e-92. Score: 301.0. Matches aSDomain:
                     nrpspksdomains_I6L50_RS29890_Condensation_LCL.2"
                     /NRPS_PKS="Domain: AMP-binding (1538-1944). E-value:
                     1.7e-101. Score: 331.7. Matches aSDomain:
                     nrpspksdomains_I6L50_RS29890_AMP-binding.2"
                     /NRPS_PKS="Domain: PCP (2052-2118). E-value: 1.1e-16.
                     Score: 52.8. Matches aSDomain:
                     nrpspksdomains_I6L50_RS29890_PCP.2"
                     /NRPS_PKS="Domain: NAD_binding_4 (2165-2404). E-value:
                     4.6e-54. Score: 175.1. Matches aSDomain:
                     nrpspksdomains_I6L50_RS29890_NAD_binding_4.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NAD_binding_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127: condensation domain-containing protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002065446.1"
                     /locus_tag="I6L50_RS29890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I6L50_29870"
                     /product="non-ribosomal peptide synthetase"
                     /protein_id="WP_219303867.1"
                     /sec_met_domain="AMP-binding (E-value: 1.1e-114, bitscore:
                     378.0, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.6e-16, bitscore:
                     55.5, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 6.8e-75, bitscore:
                     246.7, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="NAD_binding_4 (E-value: 3.5e-53, bitscore:
                     175.1, seeds: 102, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKEIQKQCEIVEELDATVGQEALWIAHQMELEKGMNNEAALIKLK
                     GNLQIETLKKALTVMVQSHPALRTLFIKRDEKIKQFIKKGIDFDIPIKDLTAFKNTEQK
                     FILKKFLDSIVNEKFNLEEGPLFKFHIIKLCEDEFILHMIFHHIIYDGCSLGIFIQQLS
                     HTYCKLLQENTGLVLESPYKSLVEFEEGFIDSAIYREGSSYWKDYLQGELPPTEFPATI
                     NKMNEPIYTNENISKNIDADLFYQIQCFAKRNNISVYRVMLSTYCALLHQMTNAEEIIV
                     GIPINTRPHTEEGNAFGYFVNTLPIRITIEKGDTFKGILNKVNKSVHLAIKYKHNPYSH
                     IVKDLNLNNNTHHNMIYSTAFNTVRITQLKIPDIESTVLTDCKRVNPFNMTWRIMRYEG
                     ETENKIEVDYNSALYKAESMNDLVERYIYLLQKLMKNVNEPIHSLDLLLKKDHRLYKDI
                     NSNTLAYPNSKTLDQLIDLQALKSPNQIAISMGDKSITYYDLQQRSNQIANYLRENDIK
                     KGQRVSITMVREIDTIVWILGILKSGGVYVPIDPNFPEKRIEYILKDSESQMIITKKEF
                     RGLIERFAIHTIYLEDFHYANSIENIVPTHTIEDTAYIIYTSGSTGLPKGVDVPHKAVI
                     NLSYSLMNQFNLDKNDVFLQFATMIFDASIMEMFPVLLCGGRMHLISEMEKRSAEEFIN
                     AINKNGITYVLLPTAFFKLIADMPKEMLLTLNSLKCVFVGGETLPAESVRKWQSKLGLK
                     IPVLNAYGPTEATVCTTIYEVNHEIKEESSNIPIGKPIANSKVFVVSPFNTLCPSGVVG
                     ELFIGGDGVAKGYINQKEKTEEAFISFEESYNCDKKMYSTGDLVRLLPSGNLEFIGRKD
                     NQVKLRGYRIELDEIERALFKHPEVKDAVVVTYQNDKIASFYLSKDNTEIKQEDLKTFL
                     SESLPDFMTPNYVFHLKTFPLSPSGKIDRKKLELQIPSLLGNMKNQYVPPISETEKRLV
                     KTWSEILNLGKYRISRDDDFFKLGGHSLIAVQVLNQIQKEFHLKIEIRDIFEHTTIASL
                     SAYIDKLMEVNTDREEHDMQVLKVADKECYKLSSAQKRIWFLNKYNAINRVYDTQLHIN
                     IEPSLKKNILQDAIRFLVERHEMLRTVFIEKNGEPRQVILKSISIDLIHDDIEHIAKKE
                     QQEYIRRTINQTDHTPFDLENGPLFRIRIFNLDKKRSYLYINLHHIITDEWSVRNLLDE
                     LMKVYNAFANRRNPELPTISNRYVDYVEWEHKQLKLGRWDTEKSYWMTELAAPLPLLNL
                     PLDFSRDRQSTNKGKVFEMKLDNKMKESLKQVCEQENVSMYMLFLAAYIQLLHYLTDQK
                     DIIVGTPVAGRNYQEFEQIQGFFVNTLAIRTQLNDVKNLKQLVQVVKEKCLNSFQNQSY
                     PFDKVIEQINPDRSFGNNPIFSTMFSYQKDILQQHDAYKLQLLPNKQDVSKFDISLAVE
                     EGSDYVEISFEYNINLFKEESINRFTQNLLNILDAFIHQRTVAYENLSFLSLEEESLYR
                     KVNHTERPYPYFQNIQEQFYKQVERQSNRIAIATETESLTYRQLNRSSNQVAQHLLEKG
                     IKTGDKVAIFLDRSINSIVSMIGILKAGAAYIPIDVKYPEDRINYIVSDSKACRIITNY
                     KYKNHLNSINYSVSIIEDIYRTTINDDVKILNKPDDLAYVIYTSGSTGKPKGTLLTHNG
                     VLNLAEWRNEVFHISPNDKVTQFYSHSFDSSVSEIFSTLLNGAELYVLSDEQRYSTFAY
                     AQAIQEIQATISDVPTVFFNELSTSLTKLDSDKIRSLRFMIMGGEAASTNAIRSWQNTF
                     KNQGQLVNEYGPTEATVSAMYYFIPDLECENNILGSIPIGIPISNTKVHILNSYMQHCP
                     VGGMGELYIESLGLAQGYWKQEEKTKQAFISNPFSEDNSKRLYRTGDLAKWLPNGNIEF
                     MGRKDKQVKIRGHRIELGEIEDSILQFEGISQAVVTQTKDGMLLQAYYKTVDGIEIEKN
                     KLAIHLSNVLPEYMIPKYYSHVLEIPITANGKIDFGKLPEIEFDNEKKDDCILKPQTKV
                     QKNIAKVWSEVLNIKSIGLKDDFFNLGGHSLKVMPALVKLKPIYPNLKIQDFFKYRTID
                     KLASHIEEMENMSLKKEKNMNVACIENETKTTPVYKRTKLEECELDMVNYPQAVFLTGA
                     TGYLGAHILERLLQLPSTTIYCLVRKNENQVIDEKLKERMSFYFGKEILKKLEERVELI
                     EGDLSLINLGLDSKQLDYLKSNVESIIHCGGEVRHYGEREHFQKVNVQSTKYLLELAKN
                     TNARYHYISTLSVVGQAESDPKEFEFFESNFDRGQNLDNVYLESKFQGEKMVREAMERG
                     VRATIYRVGNLVGNSKTGKFQYNINENAFYRLLKGICLSSIAPEINTYVDLTPVDYGSL
                     AITELSYKANTVNKTMHICNPAQLKWDRFINSLQVFGYNILSMKQEKYIEKFFNTNLTT
                     DEQIALELIMPLLESVEELSVSIPSCSYTQKYLKNVHCLKPNQEYINLLLNYAMSIEYL
                     PLFKEPILL"
     aSDomain        20040..20930
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_I6L50_RS29890_Condensation_LCL.1
                     "
                     /domain_subtypes="Condensation_LCL"
                     /evalue="1.50E-58"
                     /label="I6L50_RS29890_Condensation_LCL.1"
                     /locus_tag="I6L50_RS29890"
                     /protein_end="310"
                     /protein_start="13"
                     /score="190.1"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHIIYDG"
                     /tool="antismash"
                     /translation="LDATVGQEALWIAHQMELEKGMNNEAALIKLKGNLQIETLKKALT
                     VMVQSHPALRTLFIKRDEKIKQFIKKGIDFDIPIKDLTAFKNTEQKFILKKFLDSIVNE
                     KFNLEEGPLFKFHIIKLCEDEFILHMIFHHIIYDGCSLGIFIQQLSHTYCKLLQENTGL
                     VLESPYKSLVEFEEGFIDSAIYREGSSYWKDYLQGELPPTEFPATINKMNEPIYTNENI
                     SKNIDADLFYQIQCFAKRNNISVYRVMLSTYCALLHQMTNAEEIIVGIPINTRPHTEEG
                     NAFGYFVNTLPIRITI"
     aSModule        20040..23162
                     /complete
                     /domains="nrpspksdomains_I6L50_RS29890_Condensation_LCL.1"
                     /domains="nrpspksdomains_I6L50_RS29890_AMP-binding.1"
                     /domains="nrpspksdomains_I6L50_RS29890_PCP.1"
                     /locus_tags="I6L50_RS29890"
                     /monomer_pairings="Leu -> Leu"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       20109..20213
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_I6L50_RS29890_0001"
                     /evalue="2.60E-09"
                     /label="C2_LCL_024-062"
                     /locus_tag="I6L50_RS29890"
                     /protein_end="71"
                     /protein_start="36"
                     /score="29.5"
                     /tool="antismash"
                     /translation="NEAALIKLKGNLQIETLKKALTVMVQSHPALRTLF"
     CDS_motif       20433..20498
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_I6L50_RS29890_0002"
                     /evalue="7.20E-08"
                     /label="C3_LCL_132-143"
                     /locus_tag="I6L50_RS29890"
                     /protein_end="166"
                     /protein_start="144"
                     /score="25.0"
                     /tool="antismash"
                     /translation="FHHIIYDGCSLGIFIQQLSHTY"
     CDS_motif       20832..20921
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_I6L50_RS29890_0003"
                     /evalue="1.30E-09"
                     /label="C5_LCL_267-296"
                     /locus_tag="I6L50_RS29890"
                     /protein_end="307"
                     /protein_start="277"
                     /score="30.5"
                     /tool="antismash"
                     /translation="EIIVGIPINTRPHTEEGNAFGYFVNTLPIR"
     CDS_motif       21009..21086
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_I6L50_RS29890_0004"
                     /evalue="1.00E+01"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="I6L50_RS29890"
                     /protein_end="362"
                     /protein_start="336"
                     /score="-1.6"
                     /tool="antismash"
                     /translation="PYSHIVKDLNLNNNTHHNMIYSTAFN"
     aSDomain        21432..22631
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_I6L50_RS29890_AMP-binding.1"
                     /evalue="4.90E-104"
                     /label="I6L50_RS29890_AMP-binding.1"
                     /locus_tag="I6L50_RS29890"
                     /protein_end="877"
                     /protein_start="477"
                     /score="340.1"
                     /specificity="substrate consensus: Leu"
                     /tool="antismash"
                     /translation="QALKSPNQIAISMGDKSITYYDLQQRSNQIANYLRENDIKKGQRV
                     SITMVREIDTIVWILGILKSGGVYVPIDPNFPEKRIEYILKDSESQMIITKKEFRGLIE
                     RFAIHTIYLEDFHYANSIENIVPTHTIEDTAYIIYTSGSTGLPKGVDVPHKAVINLSYS
                     LMNQFNLDKNDVFLQFATMIFDASIMEMFPVLLCGGRMHLISEMEKRSAEEFINAINKN
                     GITYVLLPTAFFKLIADMPKEMLLTLNSLKCVFVGGETLPAESVRKWQSKLGLKIPVLN
                     AYGPTEATVCTTIYEVNHEIKEESSNIPIGKPIANSKVFVVSPFNTLCPSGVVGELFIG
                     GDGVAKGYINQKEKTEEAFISFEESYNCDKKMYSTGDLVRLLPSGNLEFIGRKDNQVKL
                     R"
     CDS_motif       21609..21650
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_I6L50_RS29890_0005"
                     /evalue="1.40E-04"
                     /label="NRPS-A_a2"
                     /locus_tag="I6L50_RS29890"
                     /protein_end="550"
                     /protein_start="536"
                     /score="15.2"
                     /tool="antismash"
                     /translation="LGILKSGGVYVPID"
     CDS_motif       21834..21893
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_I6L50_RS29890_0006"
                     /evalue="2.50E-08"
                     /label="NRPS-A_a3"
                     /locus_tag="I6L50_RS29890"
                     /protein_end="631"
                     /protein_start="611"
                     /score="26.1"
                     /tool="antismash"
                     /translation="AYIIYTSGSTGLPKGVDVPH"
     CDS_motif       22083..22118
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_I6L50_RS29890_0007"
                     /evalue="4.00E+01"
                     /label="NRPS-A_a2"
                     /locus_tag="I6L50_RS29890"
                     /protein_end="706"
                     /protein_start="694"
                     /score="-1.2"
                     /tool="antismash"
                     /translation="AINKNGITYVLL"
     CDS_motif       22278..22307
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_I6L50_RS29890_0008"
                     /evalue="8.50E-03"
                     /label="NRPS-A_a5"
                     /locus_tag="I6L50_RS29890"
                     /protein_end="769"
                     /protein_start="759"
                     /score="8.9"
                     /tool="antismash"
                     /translation="YGPTEATVCT"
     CDS_motif       22419..22508
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_I6L50_RS29890_0009"
                     /evalue="1.50E-13"
                     /label="NRPS-A_a6"
                     /locus_tag="I6L50_RS29890"
                     /protein_end="836"
                     /protein_start="806"
                     /score="42.9"
                     /tool="antismash"
                     /translation="PSGVVGELFIGGDGVAKGYINQKEKTEEAF"
     CDS_motif       22596..22661
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_I6L50_RS29890_0010"
                     /evalue="2.80E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="I6L50_RS29890"
                     /protein_end="887"
                     /protein_start="865"
                     /score="35.4"
                     /tool="antismash"
                     /translation="FIGRKDNQVKLRGYRIELDEIE"
     aSDomain        22953..23162
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_I6L50_RS29890_PCP.1"
                     /evalue="1.50E-21"
                     /label="I6L50_RS29890_PCP.1"
                     /locus_tag="I6L50_RS29890"
                     /protein_end="1054"
                     /protein_start="984"
                     /score="68.3"
                     /tool="antismash"
                     /translation="EKRLVKTWSEILNLGKYRISRDDDFFKLGGHSLIAVQVLNQIQKE
                     FHLKIEIRDIFEHTTIASLSAYIDK"
     aSDomain        23226..24128
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_I6L50_RS29890_Condensation_LCL.2
                     "
                     /domain_subtypes="Condensation_LCL"
                     /evalue="2.60E-92"
                     /label="I6L50_RS29890_Condensation_LCL.2"
                     /locus_tag="I6L50_RS29890"
                     /protein_end="1376"
                     /protein_start="1075"
                     /score="301.0"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHIITDE"
                     /tool="antismash"
                     /translation="ECYKLSSAQKRIWFLNKYNAINRVYDTQLHINIEPSLKKNILQDA
                     IRFLVERHEMLRTVFIEKNGEPRQVILKSISIDLIHDDIEHIAKKEQQEYIRRTINQTD
                     HTPFDLENGPLFRIRIFNLDKKRSYLYINLHHIITDEWSVRNLLDELMKVYNAFANRRN
                     PELPTISNRYVDYVEWEHKQLKLGRWDTEKSYWMTELAAPLPLLNLPLDFSRDRQSTNK
                     GKVFEMKLDNKMKESLKQVCEQENVSMYMLFLAAYIQLLHYLTDQKDIIVGTPVAGRNY
                     QEFEQIQGFFVNTLAIRTQL"
     aSModule        23226..27212
                     /complete
                     /domains="nrpspksdomains_I6L50_RS29890_Condensation_LCL.2"
                     /domains="nrpspksdomains_I6L50_RS29890_AMP-binding.2"
                     /domains="nrpspksdomains_I6L50_RS29890_PCP.2"
                     /domains="nrpspksdomains_I6L50_RS29890_NAD_binding_4.1"
                     /locus_tags="I6L50_RS29890"
                     /monomer_pairings="Tyr -> Tyr"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       23295..23405
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_I6L50_RS29890_0011"
                     /evalue="6.80E-09"
                     /label="C2_LCL_024-062"
                     /locus_tag="I6L50_RS29890"
                     /protein_end="1135"
                     /protein_start="1098"
                     /score="28.1"
                     /tool="antismash"
                     /translation="VYDTQLHINIEPSLKKNILQDAIRFLVERHEMLRTVF"
     CDS_motif       23625..23690
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_I6L50_RS29890_0012"
                     /evalue="7.60E-08"
                     /label="C3_LCL_132-143"
                     /locus_tag="I6L50_RS29890"
                     /protein_end="1230"
                     /protein_start="1208"
                     /score="24.9"
                     /tool="antismash"
                     /translation="LHHIITDEWSVRNLLDELMKVY"
     CDS_motif       24030..24119
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_I6L50_RS29890_0013"
                     /evalue="3.70E-13"
                     /label="C5_LCL_267-296"
                     /locus_tag="I6L50_RS29890"
                     /protein_end="1373"
                     /protein_start="1343"
                     /score="41.8"
                     /tool="antismash"
                     /translation="DIIVGTPVAGRNYQEFEQIQGFFVNTLAIR"
     CDS_motif       24168..24287
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_I6L50_RS29890_0014"
                     /evalue="9.70E-12"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="I6L50_RS29890"
                     /protein_end="1429"
                     /protein_start="1389"
                     /score="37.2"
                     /tool="antismash"
                     /translation="KEKCLNSFQNQSYPFDKVIEQINPDRSFGNNPIFSTMFSY"
     aSDomain        24615..25832
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_I6L50_RS29890_AMP-binding.2"
                     /evalue="1.70E-101"
                     /label="I6L50_RS29890_AMP-binding.2"
                     /locus_tag="I6L50_RS29890"
                     /protein_end="1944"
                     /protein_start="1538"
                     /score="331.7"
                     /specificity="substrate consensus: Tyr"
                     /tool="antismash"
                     /translation="FYKQVERQSNRIAIATETESLTYRQLNRSSNQVAQHLLEKGIKTG
                     DKVAIFLDRSINSIVSMIGILKAGAAYIPIDVKYPEDRINYIVSDSKACRIITNYKYKN
                     HLNSINYSVSIIEDIYRTTINDDVKILNKPDDLAYVIYTSGSTGKPKGTLLTHNGVLNL
                     AEWRNEVFHISPNDKVTQFYSHSFDSSVSEIFSTLLNGAELYVLSDEQRYSTFAYAQAI
                     QEIQATISDVPTVFFNELSTSLTKLDSDKIRSLRFMIMGGEAASTNAIRSWQNTFKNQG
                     QLVNEYGPTEATVSAMYYFIPDLECENNILGSIPIGIPISNTKVHILNSYMQHCPVGGM
                     GELYIESLGLAQGYWKQEEKTKQAFISNPFSEDNSKRLYRTGDLAKWLPNGNIEFMGRK
                     DKQVKIR"
     CDS_motif       24804..24842
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_I6L50_RS29890_0015"
                     /evalue="1.70E-04"
                     /label="NRPS-A_a2"
                     /locus_tag="I6L50_RS29890"
                     /protein_end="1614"
                     /protein_start="1601"
                     /score="15.0"
                     /tool="antismash"
                     /translation="GILKAGAAYIPID"
     CDS_motif       25026..25085
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_I6L50_RS29890_0016"
                     /evalue="1.40E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="I6L50_RS29890"
                     /protein_end="1695"
                     /protein_start="1675"
                     /score="29.9"
                     /tool="antismash"
                     /translation="AYVIYTSGSTGKPKGTLLTH"
     CDS_motif       25470..25499
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_I6L50_RS29890_0017"
                     /evalue="2.20E-02"
                     /label="NRPS-A_a5"
                     /locus_tag="I6L50_RS29890"
                     /protein_end="1833"
                     /protein_start="1823"
                     /score="7.8"
                     /tool="antismash"
                     /translation="EYGPTEATVS"
     CDS_motif       25620..25709
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_I6L50_RS29890_0018"
                     /evalue="9.20E-11"
                     /label="NRPS-A_a6"
                     /locus_tag="I6L50_RS29890"
                     /protein_end="1903"
                     /protein_start="1873"
                     /score="34.0"
                     /tool="antismash"
                     /translation="PVGGMGELYIESLGLAQGYWKQEEKTKQAF"
     CDS_motif       25797..25862
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_I6L50_RS29890_0019"
                     /evalue="3.20E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="I6L50_RS29890"
                     /protein_end="1954"
                     /protein_start="1932"
                     /score="38.3"
                     /tool="antismash"
                     /translation="FMGRKDKQVKIRGHRIELGEIE"
     aSDomain        26157..26354
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_I6L50_RS29890_PCP.2"
                     /evalue="1.10E-16"
                     /label="I6L50_RS29890_PCP.2"
                     /locus_tag="I6L50_RS29890"
                     /protein_end="2118"
                     /protein_start="2052"
                     /score="52.8"
                     /tool="antismash"
                     /translation="KNIAKVWSEVLNIKSIGLKDDFFNLGGHSLKVMPALVKLKPIYPN
                     LKIQDFFKYRTIDKLASHIEE"
     aSDomain        26496..27212
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_I6L50_RS29890_NAD_binding_4.1"
                     /evalue="4.60E-54"
                     /label="I6L50_RS29890_NAD_binding_4.1"
                     /locus_tag="I6L50_RS29890"
                     /protein_end="2404"
                     /protein_start="2165"
                     /score="175.1"
                     /tool="antismash"
                     /translation="LTGATGYLGAHILERLLQLPSTTIYCLVRKNENQVIDEKLKERMS
                     FYFGKEILKKLEERVELIEGDLSLINLGLDSKQLDYLKSNVESIIHCGGEVRHYGEREH
                     FQKVNVQSTKYLLELAKNTNARYHYISTLSVVGQAESDPKEFEFFESNFDRGQNLDNVY
                     LESKFQGEKMVREAMERGVRATIYRVGNLVGNSKTGKFQYNINENAFYRLLKGICLSSI
                     APEINTYVDLTPVDYGS"
     gene            complement(28017..28691)
                     /locus_tag="I6L50_RS29895"
                     /old_locus_tag="I6L50_29875"
     CDS             complement(28017..28691)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016090591.1"
                     /locus_tag="I6L50_RS29895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I6L50_29875"
                     /product="hypothetical protein"
                     /protein_id="WP_219303868.1"
                     /transl_table=11
                     /translation="MNQVLRKSKKKMMYLVGSLLISLSMFSTTSFAATEGAVKSVTNST
                     YTGIAADINLPKSVVVKDGYVNWYLGIGASKVEGGISKTPSGYKVFLNSGYNESGQNSK
                     YWNTQYDASIKDGDRVNLKLVNNGNGTVTMYVNGSPRYANQPVYGSFSQYEPVKMVQGV
                     EDTGRNSFSQASFSNVLLRTDTSGVTYKSWNNSISSSFSRHGTYGNNFTVYSQVPLSAS
                     LR"
     misc_feature    complement(28903..28916)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: strong, score: 24.45"
                     /tool="antismash"
     gene            29159..29329
                     /locus_tag="I6L50_RS29900"
                     /old_locus_tag="I6L50_29880"
     CDS             29159..29329
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016089975.1"
                     /locus_tag="I6L50_RS29900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I6L50_29880"
                     /product="hypothetical protein"
                     /protein_id="WP_219303869.1"
                     /transl_table=11
                     /translation="MGITNTRSKLDNAAIEEAIEVLKDENECLCMEIDYLKKLKAFLQK
                     EMELQNKTKQE"
     gene            <29338..29475
                     /locus_tag="I6L50_RS35890"
                     /old_locus_tag="I6L50_29885"
                     /pseudo=""
     CDS             <29338..29475
                     /GO_process="GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612077.1"
                     /locus_tag="I6L50_RS35890"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="I6L50_29885"
                     /product="IS3 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="TKFESI"
     gene            complement(29574..29870)
                     /locus_tag="I6L50_RS29910"
                     /old_locus_tag="I6L50_29890"
     CDS             complement(29574..29870)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219734.1"
                     /locus_tag="I6L50_RS29910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I6L50_29890"
                     /product="hypothetical protein"
                     /protein_id="WP_000219732.1"
                     /transl_table=11
                     /translation="MTWFIILGFMLILIISGFHAHSIHIIFKIGSDTKAVPSWSFVNKI
                     NFQTLKELIIGLNKDKLKILTIGELVIPLSFFNRLFSKTLIFLFLFFYSQYLN"
     gene            31526..32527
                     /locus_tag="I6L50_RS29915"
                     /old_locus_tag="I6L50_29895"
     CDS             31526..32527
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1078: LacI family
                     transcription regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000805134.1"
                     /locus_tag="I6L50_RS29915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I6L50_29895"
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="WP_219303870.1"
                     /transl_table=11
                     /translation="MKPTIYDVAEKAGVSIATVSKVINQTGRISEKTINKVNQVMDELD
                     YQPSSVAAALTGKKTYTIGVLVPDISNPFFAEVARAFENSARESGYTLILCSTDHQTKR
                     EHEYIDLLFKKQVDGIIIATELNDYKLVKKIVNRDLPLVLFTVDHHSITTHVVTTDDMR
                     GGYLAGSYLTQNGHTSLTIMMEKDRKSSLGRLNGFKQALTDSAISLDDDAIISCYSTVE
                     DSKRASKELLHLPNRPTAVFACTDLIAICLMNEARKQGLSIPEDLSIIGFDNTIYAEIA
                     DPGLTTIEQPIKQMAACTFEQLLKTMEMKEHAKQKITIIPQLVERFSVKDIT"
     gene            complement(32616..33896)
                     /locus_tag="I6L50_RS29920"
                     /old_locus_tag="I6L50_29900"
     CDS             complement(32616..33896)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000991326.1"
                     /locus_tag="I6L50_RS29920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I6L50_29900"
                     /product="MFS transporter"
                     /protein_id="WP_219303871.1"
                     /transl_table=11
                     /translation="MNAISSNKTFMDRIGIPSNLTWGYIGIIVFMIGDGLEQGWLSPYL
                     VEKGLTLEHAAFLFTIYGITVSASSWFSGVFVQMWGPRKVMMFGLVSFILGSIGFIGIG
                     IQHMNYPVILICYALRGFGYPLFAYSFLVWVSYSTPQQMLSRAVGWFWFVFQLGLSVIG
                     AFYSSYMVPKIGEIATLWSALIFVVVGGLFSIVVNKDKFKAQTVSANKSSELLKGITIA
                     FENPKVGIGGIVKIINSAAQFGFVVFLPTYMMKYNFTMTEWLQIWGTLFFVNMVFNIIF
                     GIVGDKFGWVNTIKWFGGVGCGIVTLALYYVPQMVGHNYWAILFVACCYGATLAGYVPL
                     TALVPSLSPENKGAAMSVLNLGSGLSAFVGPLVVTVFIGPLGVGGVMWIFAGLYFFGAF
                     LTHFLTIPKENEMEQDLNTKSGEQFSV"
     misc_feature    33987..34001
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 23.23"
                     /tool="antismash"
     gene            34392..35417
                     /gene="iolG"
                     /locus_tag="I6L50_RS29925"
                     /old_locus_tag="I6L50_29905"
     CDS             34392..35417
                     /EC_number="1.1.1.18"
                     /GO_function="GO:0050112 - inositol 2-dehydrogenase (NAD+)
                     activity [Evidence IEA]"
                     /GO_process="GO:0019310 - inositol catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="iolG"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GFO_IDH_MocA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GFO_IDH_MocA_C3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1079: oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001101872.1"
                     /locus_tag="I6L50_RS29925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I6L50_29905"
                     /product="inositol 2-dehydrogenase"
                     /protein_id="WP_219303872.1"
                     /sec_met_domain="GFO_IDH_MocA (E-value: 4.2e-30, bitscore:
                     99.7, seeds: 39, tool: rule-based-clusters)"
                     /sec_met_domain="GFO_IDH_MocA_C3 (E-value: 3.3e-32,
                     bitscore: 105.9, seeds: 4226, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNVLKIGIIGAGRIGKLHVDNLQLMPQVKIKAVSDVVISHLEKWA
                     QDKGITTLTTNYQDLLADPEIDAVFICSPTNTHAQIIKEAALAKKHIFCEKPVSFSVEE
                     TLEALEVVKDQGVSLQVGFNRRFDPNFRKVYDLIQQGEVGQPHILKITSRDPQPPSIEY
                     VRSSGGLFMDMMIHDFDMARYVMNSEVVEVFAYGTTLIDSSIQEVNDVDTAIVTLKFTN
                     GALGVIDNSRQAVYGYDQRVEVFGEKGAVAADNCCPTTVQVSNTEGVVKDKPLYFFLER
                     YTQAYIEEVTQFTKSIIEGQAVICSGNDGLQAERIAKAAKESLLTGKPVQIEHKQPALN
                     Q"
     gene            35525..36523
                     /gene="iolC"
                     /locus_tag="I6L50_RS29930"
                     /old_locus_tag="I6L50_29910"
     CDS             35525..36523
                     /EC_number="2.7.1.92"
                     /GO_function="GO:0047590 - 5-dehydro-2-deoxygluconokinase
                     activity [Evidence IEA]"
                     /GO_process="GO:0019310 - inositol catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="iolC"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1276: PfkB domain protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068606.1"
                     /locus_tag="I6L50_RS29930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I6L50_29910"
                     /product="5-dehydro-2-deoxygluconokinase"
                     /protein_id="WP_219303873.1"
                     /transl_table=11
                     /translation="MNPLIFKEDCPLDLIAVGRLCVDLNANETQRPMEETRTFTKYVGG
                     SPANIAIGAARLGLQTGFIGKVSDDQMGRFITGYLKDNNINTDQICIDRTGAVTGLAFT
                     EIKSPEDCCILMYRDNVADLNLDPTEVSEDYIKQSKALLISGTALAKSPSREAVFLALE
                     YARKHDVVVFFDVDYRPYTWQSEAETAVYYNLAAEKSDVIIGTREEFDMMEKLLNYEQS
                     NDQVTAERWFSHHAKIVVIKHGGDGSIAYTRDGQSHRGGIFKTKVLKTFGAGDSYASAF
                     IYGLMQGLEIPQAMRLGGASASIVISKHSCSDAMPTRAEISAFMETAEELV"
     gene            36602..38065
                     /locus_tag="I6L50_RS29935"
                     /old_locus_tag="I6L50_29915"
     CDS             36602..38065
                     /EC_number="1.2.1.-"
                     /GO_function="GO:0018478 - malonate-semialdehyde
                     dehydrogenase (acetylating) activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aldedh"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1017: aldehyde dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016136259.1"
                     /locus_tag="I6L50_RS29935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I6L50_29915"
                     /product="CoA-acylating methylmalonate-semialdehyde
                     dehydrogenase"
                     /protein_id="WP_219303874.1"
                     /sec_met_domain="Aldedh (E-value: 1.8e-153, bitscore:
                     506.2, seeds: 89, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVQTAQIVKNYIGGEWVESISTKMEAVYNPATGEVIAQVPLSTK
                     EDVEHAVLAANEAFKYWSKTAVPKRARILFKYQQLLVDNWEELAKLITIENGKSYNEAY
                     GEVLRGIECVEFAAGAPTLMMGKQLPDIATGIESGMYRYPIGVIGGITPFNFPMMVPCW
                     MFPLAIACGNTFVLKPSERTPLLAARLAELAAEAGIPKGVLNIVNGAHDVVNGLLEHKL
                     VKAISFVGSQPVAEYVYKKGTENLKRVQALAGAKNHSIVLNDANLELATKQIISAAFGS
                     AGERCMAASVVTVEEEIADQLVGRLVEEANKIIIGNGLDEDVFLGPVIRDNHKERTIGY
                     IDSGVEQGATLVRDGREDTAVKGAGYFVGPTIFDHVTKEMKIWQDEIFAPVLSIVRVKS
                     LDEAIEIANESRFANGACIYTDSGASVRQFRETIESGMLGVNVGVPAPMAFFPFSGWKD
                     SFYGDLHANGTDGVEFYTRKKMLTSRWEK"
     gene            38220..40154
                     /gene="iolD"
                     /locus_tag="I6L50_RS29940"
                     /old_locus_tag="I6L50_29920"
     CDS             38220..40154
                     /EC_number="3.7.1.22"
                     /GO_function="GO:0016823 - hydrolase activity, acting on
                     acid carbon-carbon bonds, in ketonic substances [Evidence
                     IEA]"
                     /GO_function="GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA]"
                     /GO_process="GO:0019310 - inositol catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="iolD"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055: pyruvate oxidase/decarboxylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001195343.1"
                     /locus_tag="I6L50_RS29940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I6L50_29920"
                     /product="3D-(3,5/4)-trihydroxycyclohexane-1,2-dione
                     acylhydrolase (decyclizing)"
                     /protein_id="WP_219303875.1"
                     /sec_met_domain="TPP_enzyme_N (E-value: 5.4e-36, bitscore:
                     118.6, seeds: 75, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 4.1e-40, bitscore:
                     131.9, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQTVRMTTAQALVKFLNQQYVEFDGEKQKFIKGIFTIFGHGNVVG
                     LGQALEEDAGELEVYQGRNEQGMANAAMAFAKQKHRKQIMACTSSVGPGSANMITSAAT
                     ASANNIPVLLLPGDVFATRQPDPVLQQIEQTHDLSISTNDAFRAVSKYWDRINRPEQLM
                     TAMIQAMRVLTNPADTGAVTICLPQDVQGEAWDFPDYFFQKRVHRIERRPPTKASLADA
                     VEMIKRKKKPVMICGGGVRYAEAAEELKQFAETFHIPFGETQAGKSAIESSHPYNLGGI
                     GVTGNIAANTIAKEADLVIGIGTRFTDFTTASKQLFQNEEVEFLNINISEFHTNKLDAL
                     KIIADAKEALLALIDELQVIDYRSSYTVEIAAAKEAWETELSRLHNICFTGQDFTPEVE
                     GHFDGKLNEYVDALGTQLTQTAVIGQINTLLDEDAIIVGAAGSLPGDLQRMWASRKPNT
                     YHMEYGYSCMGYEVAGALGAKLAEPSKEVYAMVGDGSYQMLHSELVTSLQENRKINVLL
                     FDNSGFGCINNLQMGNGMGSFGTEFRYRNQETRKLDGAIMKIDFAASAAGYGVKTYHVT
                     SLEQLQEALIDAKKQTVSTLIDIKVLPKTMTNGYESWWHVGVAEVSKSQSIQAAYESKV
                     SNLQQARSY"
     gene            40277..41173
                     /gene="iolE"
                     /locus_tag="I6L50_RS29945"
                     /old_locus_tag="I6L50_29925"
     CDS             40277..41173
                     /EC_number="4.2.1.44"
                     /GO_function="GO:0050114 - myo-inosose-2 dehydratase
                     activity [Evidence IEA]"
                     /GO_process="GO:0019310 - inositol catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="iolE"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000471977.1"
                     /locus_tag="I6L50_RS29945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I6L50_29925"
                     /product="myo-inosose-2 dehydratase"
                     /protein_id="WP_002065461.1"
                     /transl_table=11
                     /translation="MFKENTVKLGIAPIAWTNDDMPELGAENTFEQCISEMALAGFNGS
                     EVGNKYPRNTVVLKKSLELRNLEIASAWFSTFLTTKPLEETVEEFIKHRDFLHDMGAKV
                     IVVSEQGHSIQGLMDVPLFKNKPIFTEEEWDKLAEGLHNLGKLAQEKGLHIVYHHHMGT
                     GVQTTAEIEKLMDMTDPALVSLLFDTGHLVFSGEEPLYILKKYLPRIKHVHLKDIRQEV
                     VDAVKESKLSFLQAVKNGAFTVPGDGVIVFDELFTILANSDYQGWFVVEAEQDPALANP
                     FEYALKARKFIQEKAGL"
     gene            41302..42147
                     /locus_tag="I6L50_RS29950"
                     /old_locus_tag="I6L50_29930"
     CDS             41302..42147
                     /EC_number="4.1.2.13"
                     /GO_function="GO:0004332 - fructose-bisphosphate aldolase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001131823.1"
                     /locus_tag="I6L50_RS29950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I6L50_29930"
                     /product="class II fructose-bisphosphate aldolase"
                     /protein_id="WP_219303876.1"
                     /transl_table=11
                     /translation="MPLVQMKDILIKANQENYGVGAFSVANMEMVMGAIKAAEELSSPL
                     ILQIAEVRLNHSPIHMIGPLMVAAAKKATVSVAVHFDHGMTFEKIKETLEIGFSSVMFD
                     GSHYPLEENIQKTKEIVELAKQYGATVEAEIGRVGGSEDGSEDIEMLLTSTTEAKRFAE
                     ETDVDALAVAIGNAHGMYSGDPDLRLDRLQEINEVVHIPLVLHGGSGISPDIFKQCIQH
                     GVRKINVATATFQNVITRVNTTALNTPYLDYFTYQQDVIEAAYENVKNHIRIFGSENKA
                     "
     gene            42252..43043
                     /locus_tag="I6L50_RS29955"
                     /old_locus_tag="I6L50_29935"
     CDS             42252..43043
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900820.1"
                     /locus_tag="I6L50_RS29955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I6L50_29935"
                     /product="5-deoxy-glucuronate isomerase"
                     /protein_id="WP_219303877.1"
                     /transl_table=11
                     /translation="MLGKLGELNEGYNVLTEMNGQCSDMLMDIGIYKMSNGKEELLFDN
                     KNETAVLLLEGTIRLEWEGIEQVIQRQSVFEENPWCLHVAKNVKVTITALSDSEVLVQK
                     TDNDQEFASKLYTPNECQSVVAGEGVWEGTAQRVIRTIFDYKNAAYSNMVVGEVISYPG
                     RWSSYPPHHHDQPEVYYYRFNKLQGFGCAMVGEDAYRVVHNSFITIPGELDHPQATAPG
                     YAMYFCWMIRHLENNPWNDRIMEEEHKWLLEPNAKIWPEKE"
     gene            43225..44109
                     /locus_tag="I6L50_RS29960"
                     /old_locus_tag="I6L50_29940"
     CDS             43225..44109
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000104996.1"
                     /locus_tag="I6L50_RS29960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I6L50_29940"
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
                     /protein_id="WP_219303878.1"
                     /transl_table=11
                     /translation="MSTKLVNLRIDFAFKQLFGTKGNEEILTGFLNAILEESLDAPITS
                     LQLDDPHLHKSYEDDKLSILDLLATLDNGTQVNIEIQLRNTHDMVKRSLYYWSKLYTSQ
                     MQEGMPYRSLRKTITINLLDFILFSQDDAFHTIGQLWNTKMQQLLSDDIEIHFVEIPKL
                     VKQWREEKVNPWENKFVRWMLLLPAHEDEHLTQTLEEIAMNQDPILQKAINKWENMSHD
                     SSFRTAYEAREKLLLDEQAKLAHAEQEGMEKGIEQGKMQMIRGMHEIGVPLETIAKASK
                     LSVEEIERILKLK"
     gene            complement(44400..44558)
                     /locus_tag="I6L50_RS29965"
                     /old_locus_tag="I6L50_29945"
     CDS             complement(44400..44558)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000721406.1"
                     /locus_tag="I6L50_RS29965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I6L50_29945"
                     /product="Phr family secreted Rap phosphatase inhibitor"
                     /protein_id="WP_219303879.1"
                     /transl_table=11
                     /translation="MKKTKKLFLSMVVVSALACSMISLNVSQHSSFNGGDTPAPTKLIV
                     SSGVSID"
     gene            complement(44558..45658)
                     /locus_tag="I6L50_RS29970"
                     /old_locus_tag="I6L50_29950"
     CDS             complement(44558..45658)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000217983.1"
                     /locus_tag="I6L50_RS29970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I6L50_29950"
                     /product="hypothetical protein"
                     /protein_id="WP_219303880.1"
                     /transl_table=11
                     /translation="MTVQEKSNKQLMELLHEWYEEIRLYHVKEAKQTYLQVKERLKEIE
                     TDQYVSFYYSLLNFRYKVLVDGMSITKDSFNQIEKLPNIKEEFSFLAYYYYFFKAIHST
                     ISANYTEAKTHYGKAKEILIDIPDEVEKAEFEYRFSTYCYQSYQPFEAIQHVVKAKEIY
                     RNHGGYEINIALCDNVYGLACIDLREFERAEECLNTVIDVFKKYNEEQLLLRVRSNLGW
                     LYNIQDLYPLAIRQSSEIINTIPNHFKALFVLARAYYKLEGVETAKAYIEQGMKYTNEL
                     GNEEYKHRFAVLNELITELPKIKLEKVVTDAIFYFEKEDMWDCVKEYAEILALQFYEAN
                     NHVKASKYFYISNNADKKHLRKGALR"
     gene            46025..46243
                     /locus_tag="I6L50_RS29975"
                     /old_locus_tag="I6L50_29955"
     CDS             46025..46243
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002169375.1"
                     /locus_tag="I6L50_RS29975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I6L50_29955"
                     /product="hypothetical protein"
                     /protein_id="WP_033706791.1"
                     /transl_table=11
                     /translation="MISFGINLRTIISYTQESRNLNNIRILSKLGIRLFDIYGEPLPVS
                     DVNRELVTALKRQDINTQRYILSHLQG"
     gene            <46277..>46387
                     /locus_tag="I6L50_RS35105"
                     /pseudo=""
     CDS             46277..>46387
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462941.1"
                     /locus_tag="I6L50_RS35105"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="DNA-binding protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MVLSDKPRSYHQRFVKFYFLKSSELRSNILKLFNSVL"
     gene            46691..47230
                     /locus_tag="I6L50_RS29980"
                     /old_locus_tag="I6L50_29960"
     CDS             46691..47230
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017658211.1"
                     /locus_tag="I6L50_RS29980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="I6L50_29960"
                     /product="hypothetical protein"
                     /protein_id="WP_219303881.1"
                     /transl_table=11
                     /translation="MKGEENLKIFNSVASIQIKNEELPFDISWMTDWIVDWFGPLFNGG
                     SDVMKDGGDKIDGAVHASVPAFIDVIFLILSVVILISLLVFGASLWFKHIKWKKRSIYF
                     GVDSFILILLIRILPVLMLTTRSFDFQTFMSNLMGLITSIILGTAVLMFLISLALGMLY
                     KKFEHPKYGKWSLWRK"
     misc_feature    46693..46702
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 16.22"
                     /tool="antismash"
     misc_feature    complement(47401..47414)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: strong, score: 24.03"
                     /tool="antismash"
ORIGIN
        1 tattaggcaa atgaaacact tataataaag ggcttggggg agaaatagtt gattaagcta
       61 tctttacttg aaaatgcata tgattcaatt caaaatggtg ttgaatatct tgaatctgct
      121 gttaaaacag aaaatatcta tgattacaag cacgctgtat taaatctttg tcagggtaca
      181 gaactattat taaaagaaat tctattctta aaaaacccaa tatatgcttt tgataaaaat
      241 tcgttattta ataaatgtga aaaccctttg gacccgactc tagaggaatt atatgaatgt
      301 aaatcgttgg atgttaattc attgtgttat gcggtagcta agtatgcgcc tgattttagt
      361 ggaaatgaga aagtaaattt gaaaatatat gagaaacggg catcgaaatt aagaaataaa
      421 gtgcaacact tttgctttgc aattaagtct gaggaagtta gagaaatagt tttaaaatta
      481 tatcatcaag taatagcacc agctttatta tatataaata aacaacctga ccacacattt
      541 gaagaaaagt taggtaacat tttctgtagt gatgaacgta gagagcgtca tgaaatgatg
      601 ttgaatttgc aaaaagaaga ttatgcaatt ggtaattgct tttcatgtgg tcattattct
      661 ttcttcataa tgtatagagg gaattcctat ccaacagatt gttattgcac tacatgtagt
      721 tttacaattg aatctataat tgattctgac tatttagaat gtccggaatg cggaataaat
      781 tctttagtat acaatcatga attagaagct gggacttgtt taaattatag gtgtgctaat
      841 catagagacg gtggagtatt agttgatatg gaatactgct cttcttgtag ggagtataga
      901 atagaagaca cctgtcaatg tgaagaagaa gaatagtttt gtagagagat ttttgagctg
      961 acaagatagc gttgaacaac aaattagacc gatttgagat ggattattgg atatatatgt
     1021 taggagttgg atggaaatct gagattgaat gtactttaaa taaccgtaaa agtccatata
     1081 agacgaacat ctctattcga gagaaattat catttttagt tgaagcattt cctgaattaa
     1141 aggagaacag agatttttat gattggatat taagcgacta aaaaaatagt gaactaatca
     1201 ctaatgaatc cctttatatt acaatgagtg aatcaggatg atgagaatca agcacaatag
     1261 gaacagataa gagaatttta gcgtttattt ccgaataatc ttttaagagc ggggattaga
     1321 agttgccctt gctaaggtaa taatgttaag cttagcaatt atttatgtta aggctaataa
     1381 gagaatccat tttgatatat cttttcaaaa tggattcttt ttgttcgtta taaaaggatt
     1441 agtcattttt ttatgttagt tggtaattta ttccgattaa tcttctttca aaaataaagg
     1501 ttactttgta acttcatcaa taatacgctt atcgcttata tcatgcactg tctttgaact
     1561 tataacattt cataaaattc ttgattcctc ttagtatttt tagtatctca atcaatttta
     1621 taatgctcat tatacaaatg cttcctattt tcaatggatt ttttttaaaa tatacactaa
     1681 tcagttatta taataagtag taagaatatg cagttgtatg gaaaatttgg tatattatta
     1741 aggtaatata tggaggggat ataatgagcg atgtgttagt tgatttttct gaagaaatta
     1801 ggatatataa ggatagaatt agaatttttc tcatcttgta tttcctttct gaagatatgt
     1861 ctgaagaaca tggtaataat actttaaaaa aagtttttaa aagtgaagtg aaaatccaga
     1921 aagttgattt tttggtgcgt aaccccgatt actttgcata tcaaatttta ttatttgctc
     1981 aagaaaataa aattagtaaa caagaatgta aagaaattgt gaaaaatatt tttactcaaa
     2041 gagaacccag tataagaaga ctcgaaatgg aaaagttttt ttttggagcg tacgaaaata
     2101 ttgacgatgt aatcagtttt ctaaaaagca taggctttat tgactttaat agtaaaaaaa
     2161 gtttggattt aagaacaatt gaaaagcatt attatattac agagctagca tgtagaaaaa
     2221 ttgatgagat tcaaaattta aaatcattat attggtataa agaaagaata gaattaataa
     2281 aacgattctt tggagattta ggaggtacac agctcaaaga cttacagtat gaaatagatg
     2341 aatataaaga tgctagttat aaagagtgta ttagtaatat ccaagataga gtaaagaaaa
     2401 tttatttaga aatgtttgga gaagaattat atgaaattta attttgaaag atttgtagag
     2461 gaagtacata aagcttatag tgatactttt acgttaagag aagttaatga gctattgaat
     2521 acagtatatg agtataaaaa ggatactccc atttctaccg gtaaaaaact aattttaact
     2581 aagataaata ttattggaat aaaaagtagc ggtgaagaaa ttaactttag tctcccttta
     2641 aataccggtg taaatataat agtgggtgat aatcttaaag ggaaatcaag cttgtttaag
     2701 atgattcaat tggcacttac aggtagtaat aaattgaaac atgatgttaa aaaatggatt
     2761 aaatcaattt tattatcatt taaaataaac gataaacaat attctataat tataaaattt
     2821 gaaaataatc gaatgaaggg tgcattatac agtggggtaa tagataacat tgatgataga
     2881 aagatatcta agttagatcc catatttgaa acgagcacaa ttaatgagta tgaagagcaa
     2941 attcaagatt ttttctttat gcagttttct tattactcgc ttaaatggac ccaaaaaagt
     3001 tcaagtaaag aaaagaacga actcgtagaa gcaaatgcaa gttggaaaac atattttaag
     3061 tctatatatc ttgaatcaaa ggatagtgca agtttaatgt atggtagcca aggaaaaaaa
     3121 gtttttcaaa tgttattagg acttgaatta acattagtaa ttaaccaact ttcagttaaa
     3181 aaagatttct tgcaatttaa taatgctaaa caaattgatc aaacacaagg acaaaaaaat
     3241 caagataaaa aggattattt actccaaaga aaagttgatt tagaaaatga attagttgag
     3301 ttaaattcat ttaaaatgga tagtattaat caactgcatg agaaatatga aataatagtt
     3361 aatgaaatca atgatgaaaa tgctttaata actaaaaata caattgagtt aagtgaagaa
     3421 cgtaaattga taagtgaaat taattgggaa cttgatacat atactaatga attaaaaaga
     3481 ataaagaaag aaattaataa aaatgatagg gctataaatg atatgaaaga atatattgaa
     3541 atcggtatct tcttttcaaa ccttaatatt aaacaatgtc ctagttgtaa tcatgaagta
     3601 aaaaaagaaa atatccatca agaaaaaaaa tgtgtcctat gtcatgaacc agttcatgat
     3661 ttagataaag aaattaatca agatatatat tatcaaaagc ttgccgattt agaaatcata
     3721 aagaaaaaac ttaatgaaga aaagagttta attgaaaaaa aaatcataaa attcaataga
     3781 gagttcgaac aaaaaagttt aattataaaa caattagagg atcctgtgat aaatcgagaa
     3841 aaaattagtt ctctaaagaa aaaactaaaa gatattgaag aaagcatcaa taaagagatg
     3901 gaaaagctaa gtcctaaaaa tgaaagaaaa actgttttag tagctgagaa agcggttata
     3961 gattatcgtt tggataaact aacacaaagt ccggatagtc tttataaaga agaaaagaag
     4021 attgaattat tagagaaagc aattagaaag ttaaataaat taagatatga taatggacag
     4081 aagatattaa agtatctatc tgatttaatg ttagagaatc tgcatcattt tgggttaaat
     4141 tcaattacag aaattaaaat caatgaaaat tttgatatta agtataagca aaatggatac
     4201 gatcttactt ttgatagtat tgcagaagga gaacaattaa gagcaaagat agccttgtat
     4261 cttgcactta ttcaattaga tattgaatat aattttggga gacatacgag atttctaata
     4321 atagatagtc caaataaaga agaaggggat tctaattatc ttactggttt aacggaggtt
     4381 cttgtagata ttgataaaag atatggagat aatctacaaa taattattgg gacggctgaa
     4441 agaaaattag cacatatagt acaaaatgaa aaagttttta ataaaggaga atatgtattt
     4501 taatgaagga gtgtattgaa atagaaaact ttcaaaatat gaaaatacat gagaaaattt
     4561 acttcttcga tattaaaagt ccggatattt taattaattt tgatggaaaa aaagttcagc
     4621 aatttttaaa aaatattatt ttagacagtg gagaaaactt atatataagg aaaaaagcac
     4681 ttgaaaattt tatcaattta gtcatgatta agaaaataaa aaaaagatct gcattaggaa
     4741 tactgataga cgaatgggaa tttacaggcg atgatttttt agaaattact aggttaaaga
     4801 aattgtttct attttatgag gatgaaacag aagaaataga agaaatttac attgttttga
     4861 aagaacatga aaaaaatgag attaaaagtg aaagcttatt tcaattagga tgtatatatt
     4921 ttctaaaagc aaatgcaata aaggataaag aggcatatgt aaaatgttta aaaagtagtt
     4981 tggaatattt ccagaaatct aataattgta tagaaaatag aatagatgca gagttttttt
     5041 gtacagttat aaaactatta ttagacataa ttcaacacag agaaagtgaa tttcaattaa
     5101 gctttaaaaa aatggccaag ttattatggc aacaaaaact attttctttt gaaagtcagg
     5161 ttgcaccact tcaagtagga ttatttcgta cattaaatgc atttagaaaa attagtatgg
     5221 ttgaaccttc aagctggtta gattatcgaa aagaatttaa tcaactttgt tattattttt
     5281 atgaaataaa aaatcaagaa gtttgtatgg aattaatgga aagttcttta ttaaaaaata
     5341 tgaaaggtaa tttaatgagg agaacaattg aaccactatt ttcattaaac ttcaaagctg
     5401 aaatttgtaa aattgagaaa ttgttaaatg aagctgataa agagtcagag atgcataaat
     5461 ttttatctta tctaaaacag ttgatttcta agacggaagt aaaggaaaat gcagaaaaag
     5521 acataatttt cagtaagatt attaatgcat ttccaaatat agataattcg agaataaaaa
     5581 aggaatttca gaagattacg ggggatataa atacccataa aattttaaat cttttagaat
     5641 tattttcgga gtattcatat gataaattaa tagatgtaat tattaatgct tgtattaatt
     5701 tacaaggtaa tcaattatac agagataaaa cagaaaatga aagaaacaca tttttggcga
     5761 catgtttaga tatggctggt ttttacaata aagaccagac attatggagt aaatcgaatg
     5821 aggggaaaac atctggggaa atagatatct ttgttaagaa aaagaatggg ctaccatttt
     5881 caattattga ggcattgaat ttagattcat taaaaaagga ttatttagag ttacacttga
     5941 gaaaaatatt tggatatgat accactggac ttaagtacaa ttttataatt gtatattctt
     6001 cttcaaaaaa tttttcgggg ttgtggaaaa ggtatgttga tcatataaaa aaatataaat
     6061 acccttatgc aaaaatagat tataaagagg tagaagaata tgtttatgca aatataaagg
     6121 ttggtaaaac agtacattta agaaataatc aagaaatata tttggttcat ataatggttg
     6181 atttaagttt attttaagga ttgtccatat ggggttagaa tctaatcgga tattttcaat
     6241 tatgaatatc ttttaaaaat aagaaaagag ttatatattt taaaaacttc aactttaaaa
     6301 atgttgttac ggttttacca aagttaataa tagggggctt ttactatttt ttctttttgt
     6361 agagatacca agatagtagt ttgactcaaa aattaagtaa aaaaatcaac ccaaaaaaat
     6421 gttttacaag agaaaggaat ttattatgaa ggaattaaat acaggttaaa tgaaaagacg
     6481 agtatttgtt gaaggttatg agatttaaaa atagatttag aagtgctatc tataacgttt
     6541 ttagagtata aacaatcctt ttataattgt ttggagcacg aacttcaaaa aaataaacca
     6601 tcatgaggtt tttattcgaa aactcatatt tcaatagatg atgaaggtag gtaggaaaga
     6661 aagagagatt ttatataaag ttaaatcatt cgtatactga tataatgaca ccggtgaatt
     6721 cgattttacc ttcttattta gcgccagttt atcactttaa taattatatc gatacagtag
     6781 gagatacttt acatgggacg atattaagta agatgtagat acatcccaat ggatatctaa
     6841 ggttaataga agggtatctt accaaataga atttcaagct atattttact ccattaaaat
     6901 gacattagat tgcttagtag ctgtttttac atattattac aagggtctat ctgtaaaatc
     6961 tactattgtt agatataaaa aatcagaaaa gaaggaagag ctcatgggga gagttagtaa
     7021 actaagggaa agtgattacc ttttacaata cataaatgta aaatatcata agtggattaa
     7081 atttgcagtt gaacctaggg acattattac ttattatggt gatttaggaa tcaattttaa
     7141 ctttaattcg attgcttcta cataatacct attcaagtta ataacaagtt aatacggaat
     7201 aaaaaagaag aatcaacatc tactagttat aactttatgc acctagatga ttttgtttct
     7261 cttttttatg atttttatga agatattttt aacggtttat tatcaaaatc attagtagtt
     7321 tctcagggga gaataacaaa aaagatgtta cttgtttttt tgagtgttag tgctgggtta
     7381 tcgtataggg gcaaatccaa aatatcgcta attcatttca aaaaagaaca gtattttgaa
     7441 cagaagaact gactgctcga ttgatataat tactgatcca agtcaagtaa ctgtttaaga
     7501 aataaatgcc ttttaaatgg gaagaatttg cttttacttc caataacgag aattatgtaa
     7561 atgagctgtc catatggatg gcttattata ttttttgctt agcttttttt tctgaaatgt
     7621 ggcgataccc catccaatat atggacatac atctttagag actatatagt tagtatatgg
     7681 tttgtaatat tgaaatatga tgcttaagtg tatcaatttt ttatgtataa gggggatgag
     7741 tttattggta ttacctgctc cagagggaag acaaaaagaa gttttatgtt taccagaaat
     7801 aggacattat gtcgttttag ggacggctgg tagtggaaaa accactttag caattcatag
     7861 agcggcttat ttagcaaaac gttcaaaatc gaaagaaaag gttctcttgg ttacgtttaa
     7921 taagtctctt gtaacctatt taaattcact tgctgaaaac aatttatata atgttgacgt
     7981 tagaaattac caccggtttg cccgaggtta tctagatcac aaaggtatgc ttggatggaa
     8041 tgacatagtt ccatccatgg attacaatag ggaaaataaa aagctctctt ttattaaaca
     8101 atcacttaat gaggtaatag aagaacatgg caataattcg acactatcga gggcacctga
     8161 agtgttctat gaagaaatat cctggataca gaaaatgggt atttcttcgt tagaagaata
     8221 tattgatgca gaaagaattg gacgttctgg tacacggatt actagagata agaggcatta
     8281 tttctttgcc gtttatgaaa ggtatcttga tataagaggg agaaatgatt atcgttatga
     8341 ttgggacgat ctagctcata ctgtcataag tgaactagaa aatgatgatg ataatgataa
     8401 aatgtacaag catattatca ttgatgaggg acaagatctc tcaccggtaa tgcttcaatc
     8461 tttagcacta gcagtaccta aagatggaag tattacattc tttggggatg tggctcaaca
     8521 aatatatgga gggcgtttat cttggagaaa tgccggtctt aatgttacta gaaatgaaat
     8581 ttggaaattt gatcagaact atagaaatag taaagaaata gcagatttag ctattgcaat
     8641 atctaaacaa ccgttcttta accagaatac agacttagtc acaccaatag agcccgtcgc
     8701 ttctggtcca cagcctgtgt tagctgagtt tcagaatgaa gctaccgaat taaagtgggt
     8761 tattcgcaat gccgttacgc ttggtgaaag acagactgtt gctattttga tgaggactag
     8821 agaatcactt aaaaaggtta gagcactact gggggaagta ggtgtatctc ctcaagaatt
     8881 ggacggagat ttaaagaggt ggaaaaacaa tcccggagtt tctattggaa cataccactc
     8941 tgctaaggga ctagagttta atgctgtaat gattccatat tgtagcgctg ataggttacc
     9001 agatcaagat aaaattacag cattagaaga cagggatgaa gcattaggtg aagagtcaaa
     9061 acttatttat gttgcagcta ctagagctaa gcgagtatta gctattagtt acactggtgt
     9121 agtgactgaa attattcctc aagatgactc tctttacagt aaaagaaaaa tagaaaagta
     9181 ggggtgggtt tatggacgaa ttattaatta gacaggaata tcaaaaaaga aatatcactc
     9241 gtttatgtca cataactcga tctcaaaaag ctgtgcatat attaagctct gaagatggaa
     9301 tacaagctgt tgaatttctt gataaaagtt tgtatgatgc caatgatgaa ctacgtttgg
     9361 atggtaggaa ggattttatt aattgttcta tccaataccc aaatcactgg tattggaaaa
     9421 gagtaaagga taaggatcca cttttcaggg aatgggttat tttattgata aatccagaaa
     9481 tactaacatt agatacaact gagttttgtc cagtaaatgc agcaacaaaa agaggcgcgt
     9541 atatcaacag tggatattct ggttttaaag aactttttaa tgagagggtc aattatcgca
     9601 atagaccttc tcagatgctc cattgttgtc cgacagatga tcaagcggaa gtattggtgt
     9661 ataaaaatat atcaagaaaa gatatcatag gtgtagtagt cctaaatgaa gatcaaggtg
     9721 aaggtgaaag tgttaggtgg gaaatgttaa atatccctaa gtttgatata tctatagctc
     9781 cagacttatt cgatggcgaa tggagtacga aagttcgtaa aggcataaga cctatagagt
     9841 ataattacca aggaggtgca tcacttggaa aagagtgaga atcaaaagct agacaaatgg
     9901 ttaggggctt tagttggagc agcagctggt gatgcattag gatggcccaa tgaacaaaac
     9961 agtaaaaata taagtaaggc tcctcacaaa gaacaagaaa tttttcaaaa atgggagaga
    10021 cgtgatggag gccgattttg gtcacattat gaggaaatac atcctgggga atatagtgat
    10081 gatactcaat taattattgc aactgctaga agtttaagtc atggatctaa ttggaataag
    10141 ctattttcaa aagtagaact tccagcatgg atttcatatg aaagaggtgg cggaggagct
    10201 actaaaaggg ctgctgaaac ttggagaaag ggcagcaatc cttggaatgt agaaaaagaa
    10261 agtaaagaag atgttcaaag gtactttagt gccggtggaa atggtgtagc aatgcgtatt
    10321 ttaccccatg tatttagacg tgaaggggca tgggctgagg ttaaacacca ggttttccta
    10381 aatggaatat ttacacacgg tcatccaaga gcgttgattg gcgcattagt ttatgctgat
    10441 gcattaacat acttacaaaa cattgaaaaa acccttggat atggagagct tgttgattat
    10501 cttttagaac gcagagaaga atggggatca tttccgaatg tccaaaaact cgatagctgg
    10561 atgaatgctg caaatttagt atttaaagat aattatatgg gtctttggga tgaagtaact
    10621 gaagaagttc ttgaacaatt gaaaattatt aaagaaggac ttgatcaagg tgctttagat
    10681 ataggggatg aagtcctaaa aaaattgggg tgttttgaca aaaaagtaaa tggttcaggt
    10741 acagttacag ccgttgcttc tatctatctt gcatcaaaat atgcttccag tcctcgccta
    10801 gccataattg aagcagctta tttaaaaaat gctgatacgg acacattagc ttcaatggta
    10861 ggtggtttgt taggtatctt acatggttcg gagtttcttt cagtttcatg gcttgatgtt
    10921 caggactatg aataccttaa aagtcttatt caccaagaaa ataaggaaga tacaaaactt
    10981 aatggtcctt tgtttgacta ttacaatcct gagatgaaag caaagttcaa acatttacag
    11041 gttggtgaca tattaagagc agagccattt ggtagattga tgcttaaaga taagcacata
    11101 aatcgaccaa atgcgaaaaa tgcaattgtc aatacactaa aatttgtaac ggaagaaggg
    11161 caacacattt ttgttaaaac ctatgaaaaa ggatctgtag aagatgaata ccctttaaaa
    11221 gatagcaagt gtaacatgct ggtaaatcaa tcaatttcta ggtatcagca acagcaaaca
    11281 cggccttcag gttatccaga taaaccagtt ctagactcta gaaaaatcag aggtttatca
    11341 aacattttac ctgaaaagtt agagtttgat ttatgtttac agtttattgc ggatattatg
    11401 gatgaaatcg aacggaatgg tagcggtggt attaatcaga atggtttgaa gtttcttgaa
    11461 cagagatgga tgaaacatca aattgatatg aaagacattg agaaagctgt taacgttatt
    11521 ttgaaatatt aaaataaaaa agggattgga tattatttta aatatccaat ccctttttta
    11581 tttatctaat gagattgggc tgtcttaaaa ttttagtttg atgggtggcg ggacccccat
    11641 ccatcgaaaa aaatattcta actattctta aaattaaaaa ctctttacta ttttcttata
    11701 ttaatgagaa agggtgacgt gctttttatg aatatacatc aaaaacaagg gttgtctata
    11761 tttgccgaag agttatatcg atatatgtct cccgctacac ttaatcaatt agctatagaa
    11821 gctggcggag tgaaacgaaa acgtaagtgc catggtcagt attttctatc cttgtgtgta
    11881 tggttaaatc aacaaatcgc tactacctct cttactcgac tttgtagtca gttagaaacc
    11941 tcaacaggag ttttattgag tccggaggga cttactcgac actttaactc agcttctgta
    12001 actttcttgc gaactttatt tcctacactt ctacaagata aaattggagg gttatctaag
    12061 atttttcatt ctctttcagc ttactttgag cgcatgcgca tccatgattc tacaactttt
    12121 caagttccag attgattcgc ctctacttat tttggtgccg gaggatttag tcataaagct
    12181 ggtgtgaaaa ttcaattagt gtatgacttg ttgagtagat aattctctga tgtgaaaatt
    12241 gagccaggaa aactaagtga tcaggcgtat ggtgcgactc gaacaggcat gatacaaaag
    12301 aatgaactat atattcgtga cttaggatat tttcgtttac aagactttaa gtctatctaa
    12361 gataagcaag gatattattt atcacgtctt aaattaccaa ctaaaatata aagaaaagaa
    12421 ttcggaacag tggtatttaa aacaaaaccg gatcaattga gaccggtata tatacaagtt
    12481 catttggaag acatcatgaa ataattacaa tgtgaccgag ctatttgtga aaagaaaaaa
    12541 aggattacac atacagattg tacgaagctt ttgcaaggaa ttacggtata tatgacaaac
    12601 atttctacgg aatgggtacc aaaagagaaa atctatgatt tatattcccc gcgttggcaa
    12661 attgagctgt tatttaaaat atggaaatct tggtttcaaa ttcatcgttg taaatctatt
    12721 aaacaagagc ggctagaatg tcacctatat ggacaactca ttagtatcct attatgttct
    12781 tctactatgt tccaaataag ggaacctctg ttacgtgaga aacagaaaga actaagtgaa
    12841 tataaagcga tgtacatgat taaagattat ttcttacttt ttcatcaaac attgcataaa
    12901 cacacccaag aattatcaaa aattctcctt cgtctgttta accttctaca gcaaaacgga
    12961 cgaaaatccc acagatatga gaaaaaaaca gtctttgata ttgtgggtgt tgtttatgag
    13021 tttaccgctt ctattcatca ggtatcatag ttatagtaaa aaaatttaaa tccttcaggg
    13081 tttatttgat atgtctactt ttatgatatc tataaaaaac tatatggcaa gatcagtctt
    13141 tgtataaaca tatactttaa gttgatggat gtggggtctc acttcactta taagctctct
    13201 gtctttatta ttttatattg ggtatttaaa ggtataatgg tgggggtttt tgttattggc
    13261 taaaggtgtg aatgtgattt ctgagtagtt aggaaacagt aacatcaaaa ttacattaga
    13321 catatactcg catgtattac caacgatgca agaagatgca gttcacaaaa tcgatgagat
    13381 tttgtagaga atgtgaccac tggagttgta gcataggatt tttccaaaaa taaaacccgc
    13441 atcaaaagct aatttgacac ggtttctaca atatgcctcc ggagaggttc gaactcacga
    13501 ccttcaccct gtcaaaatcg ataatctttc atgattataa cagataatag atgttaaact
    13561 ctgatatatc agcatgttat taaatctata caggataaaa aatctttgaa aacgatataa
    13621 aattacgatg ttctgcccca aaagtactat tccatccatt ttagcaaaca gttatatata
    13681 agaaaattcc ttgaatatca agggattttc ttatgacccc aaagaggata taactcatga
    13741 cttttatcct gtcaaagtgg agatttttca aataatctag tcttcccttt gtattataaa
    13801 ctcccaaaac ttttttaatt cctcacgttt ttgaggagtc gcattgttta tatctttaaa
    13861 ccattgataa agctcaggat cttgaatgtc tgtagctttt cttatttcag ttgtaccaag
    13921 gaggtaatca atagatactt caaaaaaggt ggctaatttt atcaatgtat cataatcagg
    13981 ttctcgattt ccttgttcat acattgcata tgtagttcga gcaatcccta gttgttttgc
    14041 catgtcttct tgacgcagtt tgcattcttt tcgaagagtg tgtagtctag tgccaaacat
    14101 atgctacctc cttttaggtg ttttctacat caattataac gtcacaatat gtaacattta
    14161 ataaggtaca cgaaatgtgt aaaaaatatt gattttaaac ttattattat gtaatataat
    14221 cattagttac acattttgtg acaatgaaag agggggaata atgaggtttt ggttattgga
    14281 aaaacgtaaa aataaagaga aaacacaaga ttatattgca tataaggcaa gaatatctag
    14341 aagtatgtat gcaatgattg aaagtggtga aagaaatcca agtgttcctg tcgcaaagaa
    14401 tatagctagg gcactcaatt ttgattggac tctttttttt gaagagtaat gtcacgatac
    14461 gtgtaattat tgggggtgag aatttcattt ctatattgtt ttcctaaaac gaaataattt
    14521 attaattatt tttaagaaaa tattagataa gggaagtgtt taaatatgaa catgaaaaca
    14581 tttgaaatgc gtgaaaaacg attagcagaa ctactaggtg caaaggtact atgggagttt
    14641 ataagtgctg taacagagga aattgaaaag caggaattag agtcgacacc aggtttatta
    14701 gaagatctat tcatacatgt gaaagagact attcaaatac aaaatatgaa tcaacgcata
    14761 acaaaagcct ctgtaaaaac agaggctgat ggtataaata aagatacatt atttatggaa
    14821 gcgtatgtag aattaattaa tcataagttt attatttctg aattagctgt agagctttca
    14881 tctgttctaa aagaattaaa ttattttgtt caatcatctt tgccacagct tcaaagtgag
    14941 cttgattctc aagaacctca atctgcttct ctttaggaag tgattgaagt atttctttta
    15001 tttctttaca ttcgtataaa ttattctccg agtcttcgat taatttatta cggcgattgg
    15061 tgtattcaag tgcacctaaa gtcgctaatg cgcgaggatc taatcctaga atttccatgt
    15121 attcctctcc tttcctctac aataattcga taggggagag gagattcctt tagtaattta
    15181 gtaaagtctt tatacagtta tacaaattgt taatgattag tgagcatgtt atttagcagg
    15241 aatacaattg aattagactt aaaagagctt cttaaaagga agagaagaaa ggggaatcca
    15301 gtaattctta ctcttttttc ttaaatgcta aatatgacac gtttgtttcc ttttatcatg
    15361 aattttaaat gggattcttt aaggaagatt agatagctat agggtatgta atatgaatag
    15421 ataaacaaaa tgaaagagaa ttgtaaccgt cagtattata gggaatatta atgggttatc
    15481 aagtaatatg tcttaaagtg tttaaaagtg ggaatctatg tatcactcgt tacttaaaaa
    15541 gtaaaagatt agacattaaa atagtgaaaa gtatttaagt tacttgtata gatgaaataa
    15601 tggagcataa caaattaaaa cacgatgaaa catgttgaaa taaatagaaa gggatcttga
    15661 ggtaggttaa gaagagaaat aaggcatgct gagaaagtgg ctattgaatt cgaagaggtt
    15721 aaagtgtaaa aggtgtcact tatgtaagaa tgtttattgc tattttactc tatataaaaa
    15781 agaagctgta caaaagtaca gctagacttc tacacaaatt tatatggcct taatgacgaa
    15841 ttgggattga ggtatatata gtaattgagc tgctaaagaa gttgtcgtgt tagcaaatgg
    15901 atatgtttct ttataagaaa aattactata cactatttca ttcatttcca aggtcgtgaa
    15961 cagtttgttt agaatttttt gagaaatttt atttgtacaa gcagcaataa aatcaaaatc
    16021 ttttttactt atttcttgaa ttgcatgtga aagaaggctg gtgactatcc cacttcccat
    16081 ccaatctgga tgacaagcgc ccatgtctag atagaccaat ttttctttat ccaaatgaga
    16141 aaactcaata gattctgttt ctaatgtatc taaaagttga aaaataggat ccatttgtgg
    16201 gcatagttca tttgccttat ctttatctat tagtggctgg gttacttttc ttgttaaaag
    16261 aacaccgaca atttgaaaat tatctattgc tacaaatgac attgcttgag atacagcttg
    16321 ctttatcatt tcttcgcaca ttttgtgaaa aggagcaaag ggaatttgta aactgcttac
    16381 aagaggttcg ttattcacaa aagaatgtgc aagtaaatgt gctgcatctt tcacgtggtg
    16441 tgtatctaat agctctatat tcatatgttt ttcctctttt cctgatatag ttaatagtaa
    16501 ttaaaagaat aaagattttt atttaattta gttaaattta actattaaag cgctaacaaa
    16561 tatgattatt aaacatatga ataagtctgt ttagtagcaa tcgaaatatg ttcataaaga
    16621 aatgatacga tatcatctaa acattcaaca gttgtatatg gagagataga aaagaatttt
    16681 aatgtggaaa tcggatttct atcactactg tttattacat ctactacaca agaacgagtt
    16741 gtatcaccaa aaaatacttg atcgcgattt tttcctagat aattaaatag ttctatattt
    16801 aatcggtttg tatcctcaat ttcttctttt gttgcaagac ctattctttc tttttcccaa
    16861 ttttcttgac catctccatt catatagaaa cggaaggttg taattggtcc atatgtaaaa
    16921 tcatttgtga ttgcgacttg aggtagagcc tcacgcaact tctctctaaa taatagattt
    16981 acacgaacat aatttgctag taatttttga tatccttcaa ttccaaaggc taatagattg
    17041 atatacatgg gaatagcgct accagctcgt gaacattcta aggtatagcc tgtatgataa
    17101 ctcccatagg atctattacc aagataaggt gtatcatctt gttcaatgtc catcagttgt
    17161 aaatcagtat gattttttac gattaaaata cttgaagcat aaggtgtttg acctaattta
    17221 tgaaaatcaa aacatacact gtctgcaagg gacatatatt gcattttatc ttgtacgtat
    17281 tgtaaggcat ttttcacatt aggttcaaat gagagtgaat tttcttcaaa actataatta
    17341 ttaaagaaac tatagaatcc gcccattgca gaatccgcat ggatataaat aggttttaat
    17401 ttatatattt tttgtattac ttcagcgctc tctttaattt tttttatatc atcaatggta
    17461 aatgtatctg ttgaccccat agtagctaga atataaaggg ggataccgcc atttttaata
    17521 acttgtatca ttttagcctc taaatcttct atatccatag aatttgtata aggatcagtt
    17581 ttcactttta ttaagtgatt tgacccaata ccagttgctt cagctgattt taataaacta
    17641 taatgtgcat tttcagaagc aaagcaatat acattttgtg gagcgccatg ttcttttgct
    17701 aatgggaatt gtttagagat tgctaaacgt aagctcgaaa atacacaacc ttgtccaccc
    17761 catgttgtat aaccaccgct attatgtgga ttataaccaa tcagttttga aagcatggat
    17821 acaactttta cctctgcttc agctgcccct ggtccataga catcccaaac gccattacca
    17881 tttaaaagtg ccatggttag tatacccaat agtgatggaa tacttggtag tggtacagca
    17941 ttagacaagt agtatttatt gggataagga tggccattca taaattggtt tagctcttct
    18001 ataacctcag acatagtgat tccagctagt ggtatatgac tttggtgaat taagctatta
    18061 tagtatcctt ctgatttttc ctcacattta cctaaagtag ctcgctcttc attttttaat
    18121 tggtcaagat ttttaattat tttctgcata gattctaata aaagttgttg tttttcttca
    18181 tttccgtcaa cgctcggaaa tagttttaaa atatcttgca tgcagtcact tctccttgta
    18241 aaaaactgga tttttatttt acttggttaa acataagggt ataataattt gtaattgccc
    18301 tttgaatcct tagaaatgag gagctattta gaaaaaaatg taattccata gaaaattata
    18361 tgaactatgg aatttaaagt aaagaaaaat tttttgattt atttttaaaa aagtaattgt
    18421 gagataatga agtttctaaa aatatatctg aattaattgt ttatttaatt tatatcttgt
    18481 cctaacatgt attgaactag tgtagtagat attttaatat aatgtagaac gtattataag
    18541 gtagttgaat aaaagtgttc aactacctta taaactgtag aaattgtcgg gaaaagagaa
    18601 aaaatagggt ggaagtgtta aagatatgtt ctagtggaga agaagtagtg gtatggattt
    18661 gatagtaaaa ttagcatgaa tttttatgga agaataatta ttggatcaaa gttttttaat
    18721 gaattcattc tcactattta ataataatgg acgagttaag tgtaaagaat tttcttcaac
    18781 ctgagtagag ttttttgcac caggaatcgc aactgaaacg gctgggtggc ttaaaacata
    18841 acgtaaggcg atttgcgcta gacttcgatt tgatcgtaca agagaaccta gtttctctat
    18901 tttgtttaag ctatctttaa accactgttc ttttggccaa tcttttctta aatcatcttc
    18961 tggaaattga gtttcatgat taaatttccc agttaaaatt cccatcttaa gaggacctct
    19021 tatcacagca cctaaattat gtttttcaat ataaggaagg atgtcttttt caggttcttt
    19081 atttaaaata ctataatcaa attgtacaac atctaaatca tcattctgat taaaatgttt
    19141 aatataatct aaatcattag tagaaacgcc aactgctctc actttgccag atgtttttaa
    19201 ggtttggaaa gcttgtagaa aagcttctgt ttcttcaggt ttatcccacc aaatatgaca
    19261 aaagtacaca tctatataat ccgttttaag ccgtagtaaa ctagcctcaa acgcatcaat
    19321 aatcttttga ggatctccaa aaactgctgg ttgattttgg tcataatgat gaccgattaa
    19381 tccacccttt gtagaaagaa tgatatcctg ccttcgatta tttatggctt ttgcaacgag
    19441 tgtttcacta tgacctagtc cataaacatc agcaatgtca ataaaattaa cccctaggtc
    19501 aattgcttta ttgattgcat caatggattc attatctttt actgcgcccc attcatcttc
    19561 accaatcgcc caagaaccga atcctatctc agaaactatt aatccggtgt tgcctaataa
    19621 tctatattcc attatgtacg gactcctcct tttcagttta tattattaga aatatatata
    19681 tagtgacctg ttggaatatc cttgaattta ttttcggggt ataaattaga gtatatattt
    19741 taataaatat atatgagatt actttataaa aagtaattgg aattattagt aaaatgattt
    19801 tttatgctta aattgaataa aagtatgaac tttcacggta taaatatgaa ttttattcat
    19861 cattttaata actatgcaac aagtgaaata aatgttgaat ttagtcgaaa aaaatacatt
    19921 tacaaatcgt agaatatgta catatagttg taaatgtaaa tattatccgt tttgaaatat
    19981 ttataaaagg agaaattcat atgaaggaaa tacaaaagca atgtgaaatt gtagaagaat
    20041 tggatgcaac agtagggcaa gaagcattat ggatagctca tcaaatggaa ttagaaaaag
    20101 gaatgaacaa tgaagctgcc ctaataaagc taaaaggaaa tcttcaaata gagaccctaa
    20161 agaaagcgct tactgtaatg gtgcaatctc atccggcgct acgtacatta tttattaaaa
    20221 gggacgaaaa aataaaacaa ttcattaaaa agggtataga ttttgatata ccaattaagg
    20281 atttaactgc ttttaaaaac acagaacaaa aatttatttt aaaaaaattc ttagactcta
    20341 tagtgaatga gaaatttaat ttagaagaag ggcctttgtt taaattccac atcattaaat
    20401 tgtgtgaaga tgaatttatt ttacatatga tttttcatca cattatttat gatggatgta
    20461 gtttaggaat ttttatccaa caattgtctc atacgtattg taaattactt caagaaaata
    20521 caggtttagt attagaatct ccttataaga gccttgtaga atttgaggaa ggttttattg
    20581 acagtgcaat atatagagaa ggatcatcct attggaaaga ttatttacaa ggtgaattac
    20641 ctcctacaga gtttcctgct actattaata aaatgaatga accgatatat acgaatgaaa
    20701 atataagtaa gaatattgat gccgatctat tttatcaaat acaatgtttt gctaaaagaa
    20761 ataacataag tgtctatcgg gttatgttaa gtacttattg tgccttgctt catcaaatga
    20821 caaacgctga agaaattatt gtaggtattc caattaatac tagaccacac acggaagaag
    20881 ggaatgcttt tggttatttt gttaatacat taccaatacg tataacaata gaaaaggggg
    20941 atacatttaa ggggatactt aacaaggtga ataaatctgt tcatttggct attaagtata
    21001 aacataatcc atattcacat atagtaaaag atttaaatct aaataataat acacatcata
    21061 atatgatata ttcaacagca tttaatacgg taaggataac tcaattgaaa attccagata
    21121 ttgagtccac agttttaaca gattgtaaaa gagtaaatcc ttttaacatg acctggagaa
    21181 taatgagata tgaaggggaa acagagaata aaattgaggt tgactataat tcagcgttat
    21241 ataaagcaga gagtatgaat gatttagttg aaagatatat atatttgtta caaaaactaa
    21301 tgaagaatgt aaatgagcct atccattcat tggatttact tttaaaaaag gatcatcgtt
    21361 tatacaaaga tataaactca aatactcttg catatcctaa ttcaaaaaca ctagatcagt
    21421 taatcgatct acaagcatta aaatcgccaa atcaaatagc gatttcaatg ggagataaat
    21481 cgattaccta ttatgacttg cagcaaaggt caaatcaaat tgcgaattat ttacgtgaaa
    21541 atgatataaa aaagggacag cgtgtaagta ttactatggt gagagagatt gatacaattg
    21601 tgtggattct aggtatacta aaatcaggtg gagtttatgt accaatcgat ccaaattttc
    21661 ctgaaaaaag aatagaatat atattaaaag atagtgaaag tcaaatgatt attacaaaga
    21721 aagaattcag gggattaatt gaaaggtttg cgattcatac aatttatcta gaggattttc
    21781 attacgctaa ttctatagaa aatattgtac ctacacatac catagaagat acagcgtata
    21841 ttatctacac gtcaggttcg acaggtttac caaaaggagt agatgtacca cataaagcag
    21901 taattaattt atcatattca ttaatgaatc aatttaattt agacaaaaat gatgtatttt
    21961 tacaatttgc aacgatgatc tttgatgcct ccattatgga aatgtttccg gttttgttat
    22021 gcggagggag aatgcattta atttctgaaa tggaaaaacg ttctgcagaa gaatttataa
    22081 atgcaattaa caagaatggt attacatatg ttcttttacc aactgcattt tttaaattaa
    22141 tagctgatat gccaaaagaa atgttactta cattaaattc tttaaaatgt gtatttgtgg
    22201 gaggggaaac cctacctgct gaatcagttc gtaaatggca aagtaaatta gggttaaaga
    22261 ttccagttct taacgcatat ggtcctactg aagctactgt atgtacaacc atttatgaag
    22321 taaatcatga aataaaagaa gaaagttcta atatcccaat aggtaaacca attgctaata
    22381 gtaaagtttt cgtggtaagt ccgttcaaca cgttatgtcc gtcaggagta gtaggtgagt
    22441 tattcattgg tggtgatggg gttgccaaag gatatataaa tcaaaaggaa aaaacagaag
    22501 aggcatttat ttctttcgaa gaatcctata attgcgataa aaaaatgtat agtactgggg
    22561 atttagtacg tcttttacca agtgggaact tagaatttat cggaaggaaa gataatcaag
    22621 taaaactacg tgggtatcga attgagcttg atgaaattga aagagcatta tttaaacacc
    22681 cagaggtaaa agatgcagta gtagtaactt atcaaaatga caaaatcgct agcttttatt
    22741 tatcaaaaga caatacagag ataaaacaag aggacttaaa aacattctta agtgaaagtt
    22801 taccagattt tatgactcca aattatgtat ttcaccttaa aacatttcca ttatcaccaa
    22861 gtggtaagat tgatagaaaa aaattagaat tacaaatccc atctttactt ggaaatatga
    22921 agaatcaata tgtaccacca ataagtgaaa cagaaaaaag gttggtaaaa acatggtcag
    22981 agattttaaa tttagggaaa tatagaatca gcagagatga tgactttttt aaacttgggg
    23041 gacattcatt aattgctgtg caagtgttaa atcaaattca aaaagagttt catttgaaaa
    23101 tagaaattag agatattttt gagcatacaa caattgctag tctatctgct tacattgata
    23161 aattaatgga agtaaatacg gatagagaag aacatgatat gcaagtatta aaggttgcag
    23221 ataaggaatg ttataagtta tccagtgctc aaaaaagaat ctggttttta aataagtata
    23281 acgctattaa tagagtatat gatacacaac tacacataaa tattgagcca agtttaaaaa
    23341 agaatatttt acaagacgcc ataagatttt tagttgaacg acacgagatg ctacgaacag
    23401 tgtttattga aaaaaacggg gagcctaggc aggtcatatt aaaatcaata tctattgacc
    23461 ttattcacga tgatattgaa cacatagcta aaaaggaaca acaagaatat atacgtagaa
    23521 caataaatca aacggatcat acaccatttg atttggaaaa tggaccactt ttccggatta
    23581 gaatttttaa tcttgataag aaaagatcct atttatatat caatttacac catattatta
    23641 ccgatgagtg gagtgtaagg aatttattag atgaattaat gaaggtatat aatgcctttg
    23701 ctaatcgaag aaatcctgag ttaccaacta tttctaatcg atatgtggat tatgttgagt
    23761 gggagcacaa gcagttaaaa ttaggccggt gggatacaga aaaatcttat tggatgaccg
    23821 agcttgcggc gcctcttccc ctactaaatc ttccgttaga ttttagtagg gatcgtcaaa
    23881 gtacaaataa aggtaaagtc tttgaaatga agttagataa taaaatgaaa gagtctttga
    23941 aacaagtatg tgaacaagag aatgtgtcta tgtatatgct atttttggca gcatatatac
    24001 aattgttaca ctatctaacg gatcaaaaag atattattgt aggtacaccg gttgctggaa
    24061 ggaattatca ggaatttgaa caaatacaag gattttttgt aaatacttta gctattagaa
    24121 cacaattaaa tgatgtgaaa aatttaaaac aactagtaca agtcgttaaa gaaaaatgtt
    24181 tgaattcttt ccaaaaccaa tcgtacccat ttgataaagt aattgagcaa ataaatcctg
    24241 atagaagttt tggaaataac cctatctttt ctacaatgtt tagttatcag aaagatattt
    24301 tgcaacagca tgatgcatac aagcttcaat tgttacctaa taaacaagat gttagtaagt
    24361 ttgacatttc tttagctgtt gaagaaggat cggattatgt agagatttca tttgagtata
    24421 atattaatct tttcaaggaa gagtcaatta ataggtttac tcaaaattta cttaatatac
    24481 tggacgcatt tattcatcaa agaacagtgg catatgagaa tctttcattc ctatcactgg
    24541 aagaggaatc tctatataga aaggtaaatc atacagaaag accgtatcct tattttcaaa
    24601 atatacagga gcaattctat aagcaagtag aaagacaatc aaataggatt gctatagcta
    24661 cagaaacaga gtctttaaca tataggcaat taaataggag ttctaatcaa gtagctcaac
    24721 atttactcga aaaaggtata aaaacaggtg acaaagtagc catattttta gatagaagta
    24781 tcaatagtat cgtctctatg attggaatat taaaagctgg cgctgcctat ataccaatcg
    24841 atgtaaaata ccccgaggat agaattaatt atatagtaag tgacagcaag gcatgtagaa
    24901 ttataacgaa ttacaaatac aaaaatcatt tgaattcaat taattatagc gtttcaataa
    24961 tagaggatat atatcgtacg acaataaatg atgatgttaa aattttaaat aaaccagatg
    25021 acttggcata tgtaatttat acttcagggt caacaggcaa accaaaaggt acattattaa
    25081 ctcataacgg agtattaaat ttagctgaat ggagaaatga agtatttcat atttccccaa
    25141 atgataaagt aacacagttt tattcccata gttttgattc ttctgtatcg gaaatttttt
    25201 ctaccttgtt aaatggggct gaactatatg tattaagtga tgaacagcgc tattcaactt
    25261 tcgcatatgc tcaagctatc caagaaatac aagcaactat ttctgacgtg ccaacagtat
    25321 tttttaatga attatcgact tcattaacta aattggatag tgataagata cgttctttaa
    25381 gatttatgat aatgggaggg gaagctgcat caacaaatgc tattaggagt tggcaaaata
    25441 cttttaaaaa ccaagggcaa ctggtaaatg agtatggacc tactgaagca actgtttcag
    25501 cgatgtatta tttcatacca gacttagaat gcgaaaataa tattttaggt agtataccga
    25561 ttggtattcc aatttctaat acaaaggttc atattttgaa ctcatatatg caacattgtc
    25621 cggtaggggg catgggtgaa ttatatattg agagtttagg attggcccaa gggtattgga
    25681 aacaggaaga gaaaacaaaa caggcattta tttcaaatcc attttcagaa gataatagta
    25741 aaaggttata ccgaacaggt gatttagcaa agtggttacc aaatggaaat atagaattta
    25801 tgggaagaaa agataagcag gttaagatta gagggcatag aattgaatta ggggaaatag
    25861 aagattccat attacaattt gaggggataa gtcaggctgt ggtaacacaa acgaaagatg
    25921 gaatgctact gcaagcttac tataaaacag tggacggtat agaaatagag aaaaataagt
    25981 tagcaataca tttatcaaat gtattgccag aatatatgat ccctaaatat tactctcatg
    26041 tgttagaaat accaataacg gctaatggga aaattgattt cggaaaactg ccagaaatag
    26101 agtttgacaa tgagaaaaag gatgattgta tacttaagcc tcaaactaaa gtgcaaaaaa
    26161 acattgcaaa agtatggtct gaagttttaa acataaaatc tattggctta aaagatgatt
    26221 tctttaattt aggtgggcat tctttaaaag ttatgccggc attagttaaa ttaaaaccga
    26281 tatatcctaa cttgaaaatt caagacttct ttaagtatag aacaatagac aaattagcct
    26341 ctcatattga agagatggaa aatatgtcgt taaagaaaga gaaaaatatg aatgtagcat
    26401 gtattgaaaa tgaaacgaaa acgactcctg tttataaaag aactaaatta gaagaatgtg
    26461 agttagatat ggtgaattat ccacaagcag tttttcttac aggagcaaca ggatacttag
    26521 gagctcatat tttagaacga ttattacagt tgccatctac gactatttac tgtttagtga
    26581 gaaaaaatga gaatcaagta attgatgaaa agttaaaaga aagaatgagt ttttatttcg
    26641 gtaaagaaat tcttaaaaag ttggaagaga gagtagaatt aattgaagga gatttatctt
    26701 tgataaatct aggtctggat tcaaagcaat tggattattt aaagagtaac gtagagtcaa
    26761 tcatacattg tggcggagaa gttagacact atggagaacg tgagcatttt caaaaagtaa
    26821 atgttcagtc tacaaaatac ttattggaat tagctaagaa tacaaatgca cgttatcatt
    26881 atatatcgac tttaagtgtg gtaggtcagg ctgaaagcga tccaaaagaa tttgaattct
    26941 ttgagtctaa ttttgataga gggcaaaatt tagataatgt gtacttagaa agtaagtttc
    27001 aaggcgagaa aatggtcaga gaagcaatgg aaagaggagt tcgtgccacg atataccgtg
    27061 tggggaattt agtgggtaac tctaaaacgg gtaaatttca atacaatatt aatgaaaacg
    27121 cattttatag attattaaaa gggatatgcc tatctagcat agcacctgaa atcaatacgt
    27181 atgtagattt aacgcctgtg gactatggaa gtttagccat tactgaacta tcttataagg
    27241 ccaacacagt aaataaaacc atgcatattt gtaatccagc tcagctaaag tgggaccgat
    27301 ttattaatag tttacaagtt ttcggataca atattctgtc aatgaaacaa gagaagtata
    27361 tagagaagtt ttttaatacg aatctaacta ctgatgaaca gatagcatta gagcttataa
    27421 tgcctttatt agaatctgta gaagagctat ctgtatctat accatcttgt tcgtatacgc
    27481 aaaaatatct gaagaatgta cattgtttaa aaccaaatca agaatatatt aatttgttat
    27541 taaattacgc catgagtata gagtatttac cattatttaa agaaccaata cttttataga
    27601 atatattata gattatgaac aaaaaagaac ctgttttcca tggaaaacag gttctttttt
    27661 ggaaaagata acttaggggt acagaaaaga ttctttccca ataggatgga aaacgcacta
    27721 ttgagaatat aaatatgcaa ttatgtatat ttatattggt tatttttaat aatttaaaaa
    27781 tctaatatat aattaaaagg ttttttattg aattaattaa cctataaaaa acgtgggaat
    27841 taaatatttt tacgtttttt tgtacataac gtttaaataa acagcttgtc ttttgaaaag
    27901 attgaaagtt ggtatttata ttggcgagaa tatcttttac aatggaccct atataaaaaa
    27961 agtagctgca agtgcaacta ctttttttca aaaacattat tattcaaata acgcctttag
    28021 cgtaaacttg cgcttaatgg tacttgagaa taaactgtga aattgttacc ataagtaccg
    28081 tgccttgaaa atgaggaaga aattgaattg ttccaacttt tgtaggtaac cccagatgta
    28141 tctgttctta gaagtacgtt tgaaaagcta gcttggctaa aggaattacg tccagtatct
    28201 tcaaccccct gaaccatttt tactggttca tattgagaaa atgagccata tacaggctga
    28261 tttgcatatc tagggcttcc atttacatac atagtaaccg taccatttcc gttattaacg
    28321 agtttaaggt ttactcggtc accatcttta attgatgcat catactgcgt gttccaatac
    28381 ttactgtttt gacctgattc attatatcct gaatttagaa atactttata cccacttggt
    28441 gttttggaaa taccaccctc aactttagat gctccaatac ctaaatacca attcacatat
    28501 ccatctttaa caacaactga ttttggtaga tttatatcag ctgcaatccc agtataggta
    28561 ctatttgtaa cactttttac agcaccttct gtagctgcaa aactagtagt tgaaaacatt
    28621 gatagagaaa ttagaagtga accaactaga tacatcattt ttttcttact tttccttaat
    28681 acttgattca tgttagatcc cccatatttt aaattattaa attgtatgga aagttggcca
    28741 actaactaca acttacaaat taaagatata tcaggtttca tttaatgtat atatttccct
    28801 gttataagtc attgaaatgt caaatgaatt tgttttttca tatttatcaa tatagatgga
    28861 gttgacagaa taaagtagta tgtctattta aatgtaagaa gattttgtta aaaaatataa
    28921 aaacttataa gtgtgttggg gatagtatgt actacgattc atttaggaga gagaaatatg
    28981 gaatgaatat agtttttttc aatgggtaga tctgaaatat ttagaaatag attaaaaaca
    29041 aaggaaataa atgaatcgtt tttcttaagg aattcattga aatagttcgt agatgaaagg
    29101 aaatatatga tttataagac atggatttcc tatataaaag aagaaagggg atccaggtat
    29161 gggaattaca aatacaagat cgaagttaga taatgcagct attgaagagg ctatagaggt
    29221 attaaaagat gaaaatgaat gtttatgtat ggaaatcgat tacttaaaaa agttaaaggc
    29281 cttccttcaa aaagagatgg aattacagaa caagacaaag caagagtaat ttatcttaca
    29341 aaattcgaaa gtatataaca tattaagata gtattagata attatatagt tcattacaat
    29401 cgcaagataa ttaaagtaca gttaaaagga atgagtccag tacaataccg gactcacatt
    29461 caaacagccg cttaattttt tgtttaattc ttcaggtcca gttcatcata ggcgatcgat
    29521 tgttggcctg ctacgcttag tgattgttat tctttaactc atctcatatt acgttagttt
    29581 aagtattgag agtaaaagaa taggaataga aatattaatg ttttgctaaa taatctatta
    29641 aagaaactta aaggaataac aagttctcct attgtaagga ttttaagttt atccttattt
    29701 agtcctatta ttaattcttt taatgtttgg aagtttattt tattaacgaa agaccaactt
    29761 ggcacagcct ttgtatctga acctattttg aaaataatat gaatactatg tgcatgaaaa
    29821 ccgcttatta ttagaataag cataaatcct aaaataatga accaagtcat ttttcaacac
    29881 ctcctttcag tatctaatat taagatatta aaactgctga gaaagtgtgc tgttgtccat
    29941 gaaaaatatt gagaatttgt tgaggaaacg ttgaaaatgt tgcaatgcga ttgattgtag
    30001 gggagttaga gttaataatg cttgtcagat tatatgcgtg aaaaaaggaa ataggaaaga
    30061 gaacaattgc gtagactgtt ctcttaagga gcggaagtgc tgaacatttt caatgacaat
    30121 gattcaacca ttccgttaat agtatgtgca aatatttata attcatacaa gaaaggcggc
    30181 tattaaaaat agccgccttg cctcagggag agttcaagaa aatcagagat tcattatgga
    30241 tacagattgg ctgttaccaa tctattcgta gtattggaaa taatcacatg aattattcgt
    30301 aagttaaaat ctcaattcat tgtaggatga gtgacatgca aagtaaaaag agcacttttt
    30361 aaaagtgctc tttttaaggt gtgtattagg acttgaaaga ggtatcaatg acaatttaga
    30421 aggagatatc tctatacaac atatggaggt actatggaag ggtgacgata aaaaataaaa
    30481 agagcagtta gaatgaacta actgctcagc tccaggggaa ttggagactt ggttttttat
    30541 agtattagca aactttcggt gtattattcg aaagtagata tagatggtta attttaaaga
    30601 ttgtattagt gcatcttatc ctttaaatag tgttcctcca ttagtaacat gagactctcc
    30661 actttctcca atttcctcaa caggaataag tggtaaatta ttattatctg atctattatt
    30721 tctattcata gcattaaaaa attgcaagat ggatcagtaa ctagatttgg ttatgaaatt
    30781 ttttgatttt ataaaggggg aaggggtagt ttcaattatc gagacagtaa aaggaaaagc
    30841 aaaaaggatt aattttgaag aaagtgcgtg ctttaattgt attaggagtc ttaattatcg
    30901 tataactacg tcctatatag ctagggaaaa tgaacggata aattgcatag aagtctttgt
    30961 atatcatagg cttaattcta tgtatgatac ttggacattt tgggttacta gagctatcaa
    31021 tattagtagg gttagtatgt attgtatgag gtatccttat agcgatatga attagtgtta
    31081 tatagaaaaa ctaggtgttc agagcatcta aattggataa ttttttactt tgcatagaaa
    31141 aaggaaccca ggagggttcc ttttcttatt ccgatctatc ttaagcgcat ataagataat
    31201 attattttac atcttaatat taggaattac aattaataat tagaaattac cgtgaggtgg
    31261 tgttaatagg agaaaggacc acaaacatta ctgcattctc tggttgtaat gagccttgca
    31321 tttggatatt aaatgtctag taagtaaatt ggtcagattt ttttctaccg gtgtttcatc
    31381 aaggttaatt agctcgtaaa tatgaagctt tacgctataa gatagaaata cttacaaatt
    31441 tcaaaagaat tccttttatg taccaagaag caaaatatat ttatgataaa atatagaaaa
    31501 agatgattaa gaagggataa ttaaagtgaa accaacaatt tatgatgttg cggaaaaagc
    31561 aggtgtatca atagcgactg tatccaaggt aattaatcaa actgggcgta ttagtgaaaa
    31621 aacaataaac aaagtaaatc aggtaatgga tgaattagat tatcagccaa gtagtgtagc
    31681 agcagcgtta acaggtaaaa aaacatatac gattggggta cttgtcccag atatctcaaa
    31741 cccttttttt gcagaagtag caagagcgtt tgaaaatagt gcacgagaat ccgggtatac
    31801 actcatttta tgtagtacag accatcaaac aaaacgtgaa cacgaataca ttgatctatt
    31861 atttaaaaag caagtagatg gcatcattat tgcaacggag ctaaatgatt ataaacttgt
    31921 aaaaaaaatc gtgaatcgag atttgccact tgtactattc actgtagatc accattccat
    31981 cacaactcat gttgtgacaa ctgatgatat gagaggaggc tatctagctg gaagttatct
    32041 aacgcagaat ggccatacat ctttaacaat tatgatggag aaggatagaa aaagtagctt
    32101 agggagattg aatggtttca aacaagctct tacggattca gcgatatcgt tagatgatga
    32161 tgctattatt agttgctatt cgacagtgga agacagtaaa cgtgcaagta aggaattact
    32221 tcatttgcct aacagaccta cagcggtttt tgcttgtaca gatttaattg ctatatgcct
    32281 tatgaatgaa gcaagaaaac aaggactttc aattccggaa gatttatcaa taatcggatt
    32341 tgataataca atctatgctg agattgcaga tccagggtta acaacaattg agcagccaat
    32401 taaacaaatg gcagcctgta cgtttgaaca actgctaaaa acgatggaaa tgaaggagca
    32461 tgctaagcaa aaaattacaa ttattcctca gttagtagag cgattctcag taaaggatat
    32521 tacatgatag attttttata agcctatttg aatgtaacaa aagaaggtca tcgtaactaa
    32581 gtatagttag gatgaccttc ttttatattt aggatttata ctgagaattg ttctccgctt
    32641 ttcgtattta aatcctgctc catctcattt tcctttggaa tagtaaggaa atgagttaaa
    32701 aatgcaccaa agaagtacaa accagcaaag atccacatca cgccgccaac acctaatgga
    32761 ccgatgaaaa cggttactac taatggcccg acgaatgctg ataatcctga acctaaattt
    32821 aagacagaca ttgcagctcc tttattttca ggagataaag atgggactaa tgcggtaaga
    32881 ggtacataac cggcaagtgt tgctccatag caacaggcaa caaataatat tgcccaataa
    32941 ttatgtccta ccatttgtgg tacataatag agtgcaagag ttacaatacc gcaaccgact
    33001 cctccgaacc atttaattgt atttacccaa ccaaacttgt ctccaacaat accaaaaata
    33061 atattaaata ccatatttac aaagaataga gtaccccaaa tttgaagcca ttcagtcatc
    33121 gtaaaattat atttcatcat ataggtaggt aggaaaacaa caaatccaaa ctgagcggcc
    33181 gagtttataa tttttacaat accgcctata ccaactttag gattttcaaa tgcgatggta
    33241 atgcctttta gtaattcact tgatttgtta gcgcttacgg tttgtgcttt aaatttatcc
    33301 ttattcacaa caattgagaa taatccaccg acgacaacaa aaattaaagc actccataat
    33361 gtagcgattt ctccgatttt aggaaccata tagctagaat aaaaggctcc tataacacta
    33421 agccctagct ggaatacgaa ccagaaccaa ccaactgctc ttgaaagcat ttgttgagga
    33481 gtactgtaag atacccaaac tagaaaagaa taagcaaata aaggataacc gaaccctcgt
    33541 agggcatagc aaattaatat tacgggataa ttcatatgtt gaattcctat acctatgaac
    33601 ccgattgaac ctaaaatgaa tgatactaaa ccaaacatca tgacttttct tggcccccac
    33661 atttgtacaa ataccccaga aaaccaagaa gaagcagata cagtaattcc gtaaatagta
    33721 aacaggaaag cagcgtgttc tagcgttaat cctttttcaa cgagataagg ggataaccat
    33781 ccctgttcta aaccgtcccc aatcataaaa acaataatcc ctatgtatcc ccaagttaaa
    33841 ttagaaggga tcccaatcct gtccataaat gttttgtttg aactaatagc gttcattctc
    33901 ccaccaccga taagttattt tttggttaag cgcttaattc tttttgataa aaaaagtata
    33961 cgcttacatt atgaggtcgt caattaaatt ttttgacaat ttacaacttt cttttataga
    34021 ggcaatctaa ttacttattg gacaataaaa taatagtgag tatgaaaaga gagaaatacc
    34081 ttatagatgg aggtgactat ttaaaaggct cggttttctt tgttatatca gtattttaaa
    34141 agaatatatt tatagctttt tagatgattt atttctaaat tattattttt tatttttatg
    34201 taatacgttt atagagggaa cttaaaattc agatgaaaag gggagtattc caaaaaataa
    34261 aaatgttttc aatttagaat caagtgtgta taatgaagaa aaacaaggaa agcgcttaac
    34321 ttaatttaat gtgcttaacc ttatagactt tcatttcgtt tcttaaattt taatatagag
    34381 ggagaaatca tatgaacgtt ttaaaaattg ggattattgg tgctgggcga attgggaaac
    34441 tacatgttga taatttgcag cttatgccac aagtaaaaat taaagcggtt tcagatgtag
    34501 taattagtca tctagaaaag tgggctcaag ataaagggat taccactcta actacaaact
    34561 atcaggattt attagcagat ccagaaattg atgctgtctt tatttgttca ccaacaaata
    34621 cacatgcgca aattattaaa gaagcagctc ttgcgaaaaa acatattttc tgtgaaaagc
    34681 ctgttagttt ctcagtagaa gaaacattag aagcattaga agtggtaaaa gatcagggag
    34741 tatcacttca agtaggtttt aatcgtcgtt ttgatcctaa cttcaggaaa gtttatgatc
    34801 tgattcaaca aggtgaagtt gggcagccgc atatcttaaa aattacgtca cgtgatccac
    34861 aaccgccaag tatagaatat gttcgctctt caggcggatt gtttatggat atgatgattc
    34921 atgattttga tatggctcgc tatgtgatga atagtgaagt cgttgaagta tttgcatatg
    34981 gaacaacatt aattgattcc tccattcagg aagtaaatga tgttgataca gcaattgtca
    35041 cattaaaatt tacaaatgga gctttaggag taattgataa tagccgccaa gctgtttatg
    35101 gatatgacca gcgtgttgaa gtgtttggtg aaaaaggcgc ggttgctgcg gataattgct
    35161 gcccgacaac agtacaagtt tctaacacag aaggtgttgt aaaagataag ccgctttatt
    35221 tctttttaga gcgttacacg caggcttaca ttgaggaagt aacacaattt acaaagtcaa
    35281 ttatagaagg acaagctgtt atttgcagtg gtaatgatgg gttacaagca gagcggattg
    35341 cgaaagctgc gaaggaatct ttgctaacag gaaaacctgt tcaaattgaa cataaacagc
    35401 ctgcattaaa tcaataaaga gagcgcttac ttctagatag ataaataaag agtaatgaat
    35461 agtaggttta taaaaatatg aactatatca ttcattcttt cataaagcat gggaggtagt
    35521 aacaatgaat ccacttattt ttaaagaaga ttgtccatta gaccttattg cagttggacg
    35581 tttatgcgtt gatttaaatg ctaatgaaac acaacgtcct atggaagaaa ctagaacgtt
    35641 tactaaatat gtaggaggtt ctcctgcaaa tattgcgatt ggtgctgcac gtcttggctt
    35701 acaaacagga tttatcggta aagtgtccga tgaccaaatg ggccgcttta ttactgggta
    35761 cctaaaggac aacaatatta atacagatca gatatgtatc gatcgtacag gtgcagtgac
    35821 aggtttagca tttacagaaa ttaaaagccc tgaagattgc tgtattttaa tgtaccgcga
    35881 caatgtcgca gacttaaacc ttgatccaac agaggtatct gaggattata ttaaacaatc
    35941 aaaagcactc ttaatttcag gaacagcttt agcgaagagt ccttctcgcg aggcggtatt
    36001 tttagcgcta gaatatgcgc gtaagcatga tgtagttgta ttttttgacg tggattaccg
    36061 cccttataca tggcagtcag aagctgaaac ggctgtgtat tacaatctag cagctgaaaa
    36121 atctgatgtc attattggaa cgcgtgaaga attcgatatg atggaaaaac tattaaacta
    36181 tgaacagtct aatgaccaag ttacggctga aagatggttt tctcatcatg cgaaaatcgt
    36241 tgtaattaaa catggcgggg atggttcaat cgcttatacg agagacggtc aatctcatcg
    36301 aggcggtatc tttaaaacaa aggtgttaaa gacgtttggc gcgggcgact cgtatgcatc
    36361 tgcgtttatt tatggcttaa tgcaagggct tgagatccct caagcgatgc gattaggtgg
    36421 cgcttctgct tcgatcgtta tttctaaaca tagctgttct gatgcaatgc caacaagggc
    36481 agagatttct gcattcatgg aaacggctga ggaattggta tagaaatctc atgaattaat
    36541 aatcaagtaa gggcttatcc tattagatgc ttctacatta cataaaaggg agagaatgaa
    36601 tatgacagta caaacagcac aaattgtaaa aaactacatt ggcggcgaat gggtagaatc
    36661 catttcaact aagatggaag ctgtatataa tccggcaaca ggggaagtaa tcgctcaagt
    36721 accactttca acaaaagaag atgttgaaca tgctgtatta gcagcaaatg aagcattcaa
    36781 atattggtct aaaacggctg tgccaaaacg cgctcgtatt ctatttaaat atcaacaatt
    36841 actagtagat aactgggaag agttagcgaa acttattacg attgaaaacg gaaaaagcta
    36901 taacgaggct tacggtgaag ttcttcgtgg tattgagtgc gtggagtttg cagcgggtgc
    36961 tcctacatta atgatgggaa aacaattacc tgatattgca acaggtattg agtctggtat
    37021 gtatcgttac ccaattggtg ttataggcgg cattacacct tttaacttcc cgatgatggt
    37081 tccatgctgg atgttcccac ttgcgattgc ttgtggtaat acatttgtat taaaaccttc
    37141 agagcgtaca ccacttctag cagcaagatt agcagaatta gctgcagaag caggcatacc
    37201 taaaggtgta ttaaatattg taaatggtgc tcacgatgta gtaaacggtc ttcttgaaca
    37261 taaattagtg aaggcaattt catttgtagg ttctcagcct gtcgcagaat atgtatacaa
    37321 aaaaggaaca gaaaacttaa aacgcgttca agcactagca ggtgcgaaaa accattccat
    37381 tgtattaaat gatgcgaatc ttgagctagc gacaaagcaa attattagtg ctgcattcgg
    37441 ttcagctggt gagcgttgta tggccgcttc tgttgtaaca gtagaagaag aaattgcaga
    37501 tcaattagtt ggaagattag tagaagaagc gaacaaaatt atcatcggaa atggtcttga
    37561 tgaagatgtg tttttagggc ctgttattcg tgataaccat aaagagcgca caattggtta
    37621 catcgattca ggtgtagaac agggcgctac attagttcgt gatggacgcg aagatacagc
    37681 tgtaaaagga gctggttact tcgttgggcc aacaattttt gaccatgtca caaaagaaat
    37741 gaaaatctgg caagatgaga tttttgctcc tgttctatct attgttcgtg tgaaatcatt
    37801 ggatgaagcg attgaaattg ccaatgagtc tcgttttgca aatggagctt gcatttatac
    37861 agatagtggg gcaagtgtac gtcaattccg tgaaacaatt gaatcaggta tgttaggtgt
    37921 gaatgttggg gttccggcac caatggcgtt cttcccgttc tctggctgga aagactcttt
    37981 ctatggtgat cttcatgcga acggtacgga cggcgttgag ttttatacta gaaagaaaat
    38041 gcttacatct cgttgggaaa agtaatcatt aagagagaag tagaatctgt ctagttgctt
    38101 ggaagcgaaa gtaacgcaag tagtaaaaca taagaaggaa gtattaggaa tctatcaaat
    38161 tcctaatact cctttttcat atgcagaatg actgttagag atagaaagga gcaaattata
    38221 tgcaaactgt tagaatgacg actgcgcaag cattggtgaa atttttgaat cagcagtacg
    38281 tagagtttga tggagagaaa caaaagttta ttaagggaat ctttacgatt tttggtcatg
    38341 ggaatgtagt aggcctaggt caagctttag aagaagacgc aggggaatta gaagtttacc
    38401 aagggagaaa tgaacaagga atggcaaatg ctgcgatggc ctttgcaaaa caaaaacata
    38461 gaaaacaaat tatggcatgt acttcttctg ttggtcctgg atcagcaaat atgattacct
    38521 ctgcagcaac agcatctgca aataatattc ccgtgttact acttccagga gatgtatttg
    38581 caacgagaca acctgatcct gttcttcaac aaattgaaca aacacatgac ttatctattt
    38641 ctacaaatga tgcttttcgt gcagtaagta agtactggga caggataaat cgtcctgaac
    38701 aattgatgac agctatgatt caagcgatgc gtgttttaac aaatccggca gatacaggag
    38761 ctgtaacaat ttgtttacca caagatgtcc aaggagaagc atgggatttt ccagattact
    38821 tcttccaaaa gcgtgttcac cgtattgaac gtcgtccacc tacaaaagcc agcttagcgg
    38881 atgcagtgga aatgattaag agaaagaaaa agccagttat gatttgcggt ggtggtgtaa
    38941 gatacgcaga agcggcagaa gagttaaaac agtttgctga aacattccac attccatttg
    39001 gagaaacaca agctggaaaa agtgcgattg aaagtagtca tccatataat cttggtggca
    39061 tcggggtaac tggaaatata gcagctaata caattgcaaa ggaagcggat cttgttattg
    39121 ggatcgggac gagatttact gattttacaa cggcatctaa acaattattt caaaatgagg
    39181 aagttgagtt tttaaacatc aatatttcag aattccatac caataagctg gatgcattaa
    39241 agattatagc ggatgcgaaa gaagcgcttc ttgctctaat tgatgaactg caagtaattg
    39301 attatcgatc tagttataca gtggaaattg ctgctgcaaa agaggcttgg gaaacagaat
    39361 tatcacgtct acataatatt tgctttacag gtcaagattt cacaccagaa gtagaaggcc
    39421 atttcgatgg aaagttaaat gagtatgtag acgcacttgg tacacaatta acacagactg
    39481 cagtcattgg acaaatcaat acattacttg atgaagatgc aattatcgtt ggagcggcag
    39541 gaagtcttcc aggtgattta caaagaatgt gggcatcaag aaaaccaaat acatatcaca
    39601 tggagtatgg atactcttgc atgggctatg aggttgcggg cgcactaggt gcaaagctag
    39661 ctgaaccatc gaaggaagta tatgcaatgg taggggatgg tagttaccag atgcttcatt
    39721 ctgagcttgt cacaagtctt caagaaaaca gaaaaattaa cgttttattg tttgataact
    39781 ccggatttgg ttgcattaat aacttacaaa tgggtaatgg aatggggagc tttggaacag
    39841 agtttcgcta ccgaaaccag gaaactcgta aattagacgg ggcaattatg aaaattgatt
    39901 ttgcagctag cgcagctgga tatggtgtga aaacatatca tgttacatca ctagaacaat
    39961 tacaggaagc gcttatagat gcgaaaaaac aaacagtttc cacattaatt gatattaaag
    40021 tattacccaa aacaatgaca aatggatacg agtcatggtg gcatgtaggt gttgcggaag
    40081 tatctaaaag tcaaagtata caagctgcgt acgagagtaa agtaagtaac ttgcaacagg
    40141 caagatctta ttagattagg acacaaagag agcttcttat ctacatgcat attgattagg
    40201 aagctctctt ttcaataacc agttaagaga atttggcgaa attctatcac attttgtaaa
    40261 gaggagagac aaggggatgt ttaaagaaaa tacagttaag cttggtattg caccaattgc
    40321 ttggacaaat gatgatatgc cggagctagg ggcagaaaac acgtttgaac aatgtattag
    40381 tgagatggca ctagctggat ttaatggaag tgaagtaggg aataaatatc cgagaaatac
    40441 agttgtatta aaaaaatctt tggaattacg aaacttggag attgctagtg catggtttag
    40501 tacgttttta acaacgaagc cacttgaaga gacagtagaa gaatttatta agcataggga
    40561 tttcttgcat gacatgggtg caaaagtcat cgttgtttca gagcaagggc atagtattca
    40621 aggtttaatg gatgtaccac tatttaaaaa taagcctatt tttacagaag aagagtggga
    40681 taagcttgcg gagggtttgc ataacctcgg taaattagct caagaaaagg ggctgcatat
    40741 tgtataccat catcatatgg gtacaggtgt tcaaacaacg gcagaaattg aaaagttaat
    40801 ggacatgact gatccagcgc ttgtatctct gctttttgat acaggtcatc ttgttttttc
    40861 aggagaagag ccactttata ttttgaagaa atatttacct cgtattaaac acgtacattt
    40921 aaaagatatt cgtcaagaag tagtagatgc tgtaaaggaa agcaaattaa gtttcctaca
    40981 ggcagtgaag aatggagcat ttacagttcc cggggatggc gtaattgtgt ttgatgaatt
    41041 gtttactatc cttgcaaact ctgattatca agggtggttt gtggtagaag cagagcaaga
    41101 cccagcttta gcgaatccct ttgaatacgc attaaaagcc cgaaaattta tacaagaaaa
    41161 agcaggtctg taatttaagc attttaagat tatccctaag taaatggtat ggtaatcaac
    41221 atatcttctt acaaaagggg taaaaagacg tgaaggttgg ttttacatgt aataaataat
    41281 attgaaatag gggagtatgt aatgccatta gttcaaatga aagatatttt aattaaagca
    41341 aatcaagaga attatggggt tggagctttt agtgtcgcta atatggaaat ggtaatggga
    41401 gctattaaag cagctgaaga gttaagttca ccgcttattc tacaaatcgc ggaagttcgt
    41461 ttgaatcatt cgccaattca tatgattggt cccttgatgg tagctgcagc aaaaaaagca
    41521 actgtttcag tagcagttca ctttgatcac gggatgacgt ttgaaaagat taaagagacg
    41581 ttagagattg gctttagctc ggttatgttt gatggctctc actatccatt agaagaaaat
    41641 atccaaaaga caaaagaaat tgtagaactt gcgaaacagt atggagcgac ggtagaggcc
    41701 gagattggta gagttggtgg tagtgaggat ggatcagaag atattgaaat gttgctgaca
    41761 agcactacag aagcaaaacg atttgcagaa gaaacagacg tagatgcgtt agctgttgca
    41821 attggaaatg cgcatggtat gtacagtgga gatcctgatt tacgattaga ccgtctacag
    41881 gaaattaatg aggtagttca tatcccgctc gtattacatg gtggatctgg aattagccca
    41941 gatattttta aacaatgcat ccaacatggt gttcgaaaaa ttaatgtagc aacagccacg
    42001 tttcagaatg taattactag agttaacact acggccttaa atactcctta tttagattac
    42061 tttacgtacc aacaagatgt aattgaggcc gcatacgaaa acgttaaaaa tcatatacgc
    42121 atattcggaa gtgaaaacaa agcataacca gaaaagcctt cttcattaaa taatagaagg
    42181 aactcataat ttagttagtt gacaaaagta gagaatgata gagtagccat taaaaaaagg
    42241 aggagaacat catgttagga aaattaggtg aattaaatga aggctataat gtattaacag
    42301 aaatgaacgg tcaatgcagt gatatgttaa tggatatagg catatataag atgtctaatg
    42361 gaaaagaaga gttgctattt gataataaaa atgaaacggc agtactttta ctagaaggga
    42421 caatacgtct agagtgggaa ggaatagaac aagttattca aagacagtct gtttttgaag
    42481 aaaacccttg gtgtttacat gtggctaaaa atgtgaaggt tacaattact gctctttcag
    42541 atagtgaagt gcttgttcaa aaaacagata atgatcaaga atttgcgtcc aagttgtata
    42601 ctccaaatga gtgtcaaagt gttgtagctg gagaaggagt atgggaggga acagcacaac
    42661 gtgttattcg tacgattttt gactataaaa atgcagcata ttctaatatg gtagtaggag
    42721 aagttatttc ttatccaggt cgatggtcta gttatccacc gcatcatcat gaccagccag
    42781 aggtatatta ttatcgcttt aataagctgc agggatttgg atgtgcaatg gtaggtgagg
    42841 atgcttatcg cgttgtacat aatagcttca ttacaattcc gggtgagcta gaccacccac
    42901 aagcaacggc acctggatat gcaatgtatt tttgttggat gattcgacat cttgagaata
    42961 acccatggaa tgatcgtatc atggaggaag aacacaagtg gttattagaa ccaaatgcga
    43021 aaatttggcc agaaaaagaa tagatgaaaa taaaggttct ggacaaaaac gatgtcactt
    43081 gcaattgttt ttgctaagaa ccactaattt tttgtcaatg taggcaggct cttatgtgag
    43141 gtaacgtaag agcctgtttg catgttctac ctttttttat gtacaatagt aataagagat
    43201 gatatagaca gggagaggaa atccatgtcc actaaattag taaatttacg gattgatttt
    43261 gcttttaaac agctatttgg aacaaaagga aatgaggaaa ttttaacggg tttcctaaat
    43321 gcaattttag aggaatcttt agatgcacct attacttcgc tacaattaga tgatccacac
    43381 ctccataaat cttatgaaga tgataagtta tcgattttag atctattagc aacactagat
    43441 aatgggacgc aagtaaatat agaaatccag cttcgaaata cacatgatat ggtgaagcga
    43501 tctttatact attggagtaa actatataca tcccaaatgc aagaagggat gccatatcgt
    43561 tcacttcgaa aaacaattac gattaactta ctagacttta ttttattttc tcaggatgat
    43621 gcatttcata ccatcggaca attatggaat acaaaaatgc agcaactatt aagtgacgac
    43681 attgaaatcc attttgtaga gataccgaaa ttggtaaaac aatggcgtga agaaaaagta
    43741 aacccgtggg aaaataaatt tgttcgttgg atgttattat taccagcaca tgaagatgaa
    43801 catttaactc aaacattgga ggagattgcg atgaatcaag atccaatttt acaaaaggcg
    43861 ataaataaat gggagaatat gagccacgat tcttctttcc gaacagcata tgaagctcga
    43921 gagaaattac ttctagatga acaagctaag ctagcacatg cagaacaaga gggtatggaa
    43981 aaaggcattg agcaaggtaa gatgcaaatg attcgaggga tgcatgaaat tggtgtgccg
    44041 cttgaaacta ttgcaaaagc aagtaagttg agtgtggagg aaatagaacg tatcttgaaa
    44101 ttaaagtaaa tatatatgta cctacagtac tcatgaataa aagaaagtag atactcatta
    44161 tcatggtatg tttaatagaa aagcattgct gaagatttta gcagtgcttt ttctcaatca
    44221 actttttaat atttttcatt ctgctcacaa ttatatagaa aagttgaaag aagaacgtga
    44281 atagtccgaa acaaatatgt ttcggacaag gggttcaata ttttatccat gtatttaaca
    44341 ttttttaaaa attaagaggc tgaattttct gattttaaaa gcaagaaaaa tgtattacgt
    44401 taatcaatag atactccact agagacaatc agttttgttg gtgctggcgt atctccacca
    44461 ttaaacgaag agtgttgtga tacatttaaa ctaatcatgc tacatgctaa tgcacttact
    44521 actaccatac ttaaaaacaa tttttttgtt tttttcatta ccttaacgct ccttttctca
    44581 aatgtttctt atcagcatta ttgctaatat agaaatattt gctcgcttta acatgattat
    44641 ttgcctcgta aaattggagt gctaaaatct ctgcatattc ttttacacaa tcccacatgt
    44701 cctctttttc aaaataaaaa attgcatcag taactacttt ttctagttta attttaggta
    44761 gttctgtgat tagttcattt aaaactgcga aacgatgctt atattcctca tttcctaatt
    44821 catttgtata cttcattcct tgctcgatat atgcttttgc tgtttcaacg ccttctaatt
    44881 tataatatgc tcttgctaag acaaataatg ctttaaaatg attcggtatg gtatttataa
    44941 tctcagaact ctgtctaatc gccaatggat atagatcttg aatattatat aaccagccta
    45001 aattggatcg tactcgtaat aataattgtt cttcattata cttcttaaaa acatcaataa
    45061 ccgtattgag acattcttcc gctctttcaa attctcttag atctatacaa gccagtccat
    45121 atacattgtc gcataaagca atattaattt catagcctcc atgattccgg tatatttctt
    45181 tggcttttac tacatgttga atcgcttcaa atggttgata agattgataa cagtaagttg
    45241 aaaatctata ctcaaactcg gctttttcta cttcatcagg tatatcaatt aaaatttctt
    45301 ttgcctttcc atagtgtgtt ttcgcttcag tataatttgc tgaaattgta gagtggattg
    45361 ccttaaagaa ataataatag taagctaaaa atgaaaattc ctctttgata ttagggagtt
    45421 tttctatttg attaaaagaa tcttttgtaa tactcattcc atctaccaag actttatatc
    45481 taaaattcag tagggaataa tagaatgata catattggtc tgtttctatt tcctttaaac
    45541 gttcttttac ttgtagatat gtctgttttg cttcttttac atgatataaa cgaatttctt
    45601 cataccattc atgtaatagt tccatcaatt gtttattact tttttcttga acagtcataa
    45661 tatcccccat ttctctgtaa aggcttattc tgataataac aggaattaga tacattaaat
    45721 gtaactacga tttttttcat taatatacag aatattccga attataataa tgtccatgct
    45781 tttaaatttg aaatagtata gttaagacag tactagtttc gttaatggtt ttttcaaaat
    45841 ttattaatgg ttgtctattg aatacttctt ataagaggtg gcgtagcact atattagaaa
    45901 gagagagagt ttatactgtt atggtattga gaaatatata gggcttatta agcttcaagg
    45961 gattcctcga aaataaatag aagtatatcc atatctattt acattgaaga gggagcgtta
    46021 gtttatgata agttttggga ttaatttacg cactattatt agttatacac aagagagtag
    46081 gaatcttaat aatatacgga ttttaagtaa gttgggtata agattatttg atatatatgg
    46141 agaaccatta cctgtatcag atgttaatcg agaattagta acggcattaa aacgccaaga
    46201 cataaatacg caaagatata tattaagtca tttacaaggt tagaaaaacc gatattatgt
    46261 tgcatttttt catacgtatg ttctatccga taaaccaaga agctatcatc aaaggtttgt
    46321 gaaattttat tttcttaaat cgagtgaatt acgtagtaat attttaaaat tatttaattc
    46381 ggtactatag tttgtatcac catgaaatgt ataaaactcg tctatgtcaa taaaaacaga
    46441 ataaagaatg tgtaatgaag tacccatcca attattatgt gtatcacaat tggatgggta
    46501 cttttttact tattccaaaa taggtacaaa gctaaatgca acggatcgtt atcaaaacgc
    46561 gagtgtacaa atgtaacaaa tgaaatttct attcataagt gtggtccttc tatttaatca
    46621 agtatgattt aatacttgat tagttttggt taaggaaatt tatatactta aagtaaaggg
    46681 gggattttta atgaaggggg aggagaattt gaaaattttc aactcagttg cttctataca
    46741 aataaaaaat gaagagttac catttgatat ttcctggatg accgattgga ttgtagactg
    46801 gtttggtcct ttgtttaatg gcggcagtga tgtaatgaaa gatgggggag ataaaataga
    46861 tggggcagtt catgcgagtg tgcctgcatt tattgatgtt attttcctta tcctttctgt
    46921 agtaatttta atttctttat tagtttttgg agcttcttta tggtttaagc atataaagtg
    46981 gaaaaagcga tccatttatt ttggagtaga ttcatttata ctcatactac taataaggat
    47041 tttaccagtg ttaatgctga caacccgttc ttttgatttt caaaccttta tgagtaattt
    47101 gatgggctta attacttcta taattttagg aacagctgtt ttaatgtttt taatatctct
    47161 agcattaggt atgctttata agaaatttga acatcccaaa tatggaaaat ggagtctttg
    47221 gaggaagtaa aggttgattt tgatattaat ggaaccaaag taagattaca taaaaagcct
    47281 aagttaaaga aaagtatata taaaataaag agtgatagat aactcctcaa tagtaactgt
    47341 cagctaaaaa tgaagatacg gtactgtaat ggagggaagg tcacataaaa tgatcaatct
    47401 tttttataaa aaattacgga ttctaaaatg aaaacccaga ggtcattctg tcaaatccat
    47461 caagatagct taattataaa cacaaataga attaaaacac aaaatatgag tttatagttc
    47521 ataaatagat actaaataca aaataaagaa gaatccataa ttcactggaa tcttctttat
    47581 tgatttttta cttgctaat
//
