LOCUS       NZ_JAHPZL010000004     22703 bp    DNA     linear   CON 18-AUG-2024
DEFINITION  Austwickia sp. TVS 96-490-7B contig_4, whole genome shotgun
            sequence.
ACCESSION   NZ_JAHPZL010000004
VERSION     NZ_JAHPZL010000004.1
KEYWORDS    WGS; RefSeq.
SOURCE      Austwickia sp. TVS 96-490-7B
  ORGANISM  Austwickia sp. TVS 96-490-7B
            Bacteria; Actinomycetota; Actinomycetes; Micrococcales;
            Dermatophilaceae; Austwickia.
REFERENCE   1  (bases 1 to 382426)
  AUTHORS   Bruer,T., Sarker,S., Lynch,S., Jack,C., Helbig,K., Isberg,S. and
            Tscharke,D.C.
  TITLE     Draft genome assembly of Dermatophilus crocodyli, causative agent of
            dermatophilosis in saltwater crocodiles and a proposed taxonomic
            reassignment to Austwickia crocodyli
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 382426)
  AUTHORS   Bruer,T., Sarker,S., Lynch,S., Jack,C., Helbig,K., Isberg,S. and
            Tscharke,D.C.
  TITLE     Direct Submission
  JOURNAL   Submitted (21-JUN-2021) Immunology and Infectious Disease,
            Australian National University, Garran Road, 131, Canberra, ACT
            2601, Australia
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 2021
            Assembly Method                   :: SPAdes v. 3.13.2
            Genome Representation             :: Full
            Expected Final Version            :: No
            Reference-guided Assembly :: GCA_900187045.1; GCA_003391095.1;
            GCA_012277275.1
            Genome Coverage                   :: 115.0x
            Sequencing Technology             :: Illumina NextSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_019331795.1-RS_2024_08_18
            Annotation Date                   :: 08/18/2024 02:33:31
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,297
            CDSs (total)                      :: 3,245
            Genes (coding)                    :: 3,183
            CDSs (with protein)               :: 3,183
            Genes (RNA)                       :: 52
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 14 of 62
            Pseudo Genes (incomplete)         :: 53 of 62
            Pseudo Genes (internal stop)      :: 9 of 62
            Pseudo Genes (multiple problems)  :: 13 of 62
            CRISPR Arrays                     :: 3
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 12:42:56
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 326569
            Orig. end                         :: 349272
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JAHPZL010000004.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22703
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-ii"
                     /region_number="1"
                     /rules="cds(LANC_like and DUF4135)"
                     /tool="antismash"
     cand_cluster    1..22703
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22703
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12703](+)"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12703
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     gene            complement(1300..2625)
                     /locus_tag="KEM60_RS07340"
                     /old_locus_tag="KEM60_01526"
     CDS             complement(1300..2625)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1212:
                     sodium:dicarboxylate symporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015883316.1"
                     /locus_tag="KEM60_RS07340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KEM60_01526"
                     /product="dicarboxylate/amino acid:cation symporter"
                     /protein_id="WP_219106862.1"
                     /transl_table=11
                     /translation="MSATASSDIAAPDTGGDDLSPPSRRRFRLSYTTQVLVALALGVVL
                     GYLAREAQITWLATTLGTIGSLFVQLLKLAVPPLVFTAVVSSIAHLRGVTNAARLAGKT
                     LVWFAITGLASSLIGLALGLLTHPGRGVSLDLGAAKAPEKAGGWTDFLTGIIPTNPVGA
                     FVQGNVLQIVFLGVVVGLAAVQVGDKAEPFLAVVDAALEITQKALWWVILLAPLGTLGL
                     IGKAVATYGWDLLAPLATFAVDVYVGCFLVLLVLYPAVLMFAAKLNPVRFFAGAWPAIQ
                     LAFVSRSSVGTMPLTQEVTVDRLGVPKDYAAFAVPFGATSKMDGCAAIYPALASIFVAE
                     VFGMHLSVPQLALIVLVSVVGSAATAGLTGAIVMLTLTLSTLGLPLAGAGLLLAIDPIL
                     DMMRTATNVAGQALVPVVVAAREGLLDREVYDAPKGDLPIHG"
     CDS             complement(2652..2828)
                     /gene="allorf_329221_329397"
                     /locus_tag="allorf_329221_329397"
                     /protein_id="allorf_329221_329397"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MSCRGRQHPSRGAWALWGIPGEGRKFTFRGQHLEPDRTQVRRPAS
                     SGCVYLSGLTSPT"
     CDS_motif       complement(2790..2828)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MSCRGRQHPSRGA"
                     /locus_tag="allorf_329221_329397_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(2652..2789)
                     /prepeptide="core"
                     /locus_tag="allorf_329221_329397_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-5.10"
                     /molecular_weight="4872.5"
                     /monoisotopic_mass="4869.6"
                     /core_sequence="WALWGIPGEGRKFTFRGQHLEPDRTQVRRPASSGCVYLSGLTS
                     PT"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MSCRGRQHPSRGA"
                     /leader_location="[2789:2828](-)"
                     /alternative_weights="4890.5"
                     /alternative_weights="4908.5"
                     /alternative_weights="4926.5"
                     /alternative_weights="4944.5"
                     /alternative_weights="4962.6"
                     /alternative_weights="4980.6"
                     /alternative_weights="4998.6"
     gene            2968..3342
                     /locus_tag="KEM60_RS07345"
                     /old_locus_tag="KEM60_01527"
     CDS             2968..3342
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025379.4"
                     /locus_tag="KEM60_RS07345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KEM60_01527"
                     /product="antitoxin"
                     /protein_id="WP_219106863.1"
                     /transl_table=11
                     /translation="MSFLEEFSKVAQKALQEAEVVTAKARQAAGAAADAHRDKIDDYIG
                     KAGTFIDEKTEGKYHQQVIKAQDVAGKGVDIVAQQKSATIPDRPAAQPKDDSADTPQTP
                     RDAAPKAPAEPDREDGSPTA"
     CDS             complement(3350..3442)
                     /gene="allorf_329919_330011"
                     /locus_tag="allorf_329919_330011"
                     /protein_id="allorf_329919_330011"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MWQDRRSGSFGGSVCRRRVAGGPDADPAVT"
     CDS_motif       complement(3407..3442)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MWQDRRSGSFGG"
                     /locus_tag="allorf_329919_330011_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(3350..3406)
                     /prepeptide="core"
                     /locus_tag="allorf_329919_330011_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-2.70"
                     /molecular_weight="1791.0"
                     /monoisotopic_mass="1789.9"
                     /core_sequence="SVCRRRVAGGPDADPAVT"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MWQDRRSGSFGG"
                     /leader_location="[3406:3442](-)"
                     /alternative_weights="1809.0"
     CDS             complement(3355..3534)
                     /gene="allorf_329924_330103"
                     /locus_tag="allorf_329924_330103"
                     /protein_id="allorf_329924_330103"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MTGFLVRQGRDRKSGFGAASGSFSSVASVNGCGRIGDQDLLADQC
                     VVGVSRAALMPILP"
     CDS_motif       complement(3481..3534)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MTGFLVRQGRDRKSGFGA"
                     /locus_tag="allorf_329924_330103_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(3355..3480)
                     /prepeptide="core"
                     /locus_tag="allorf_329924_330103_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.40"
                     /molecular_weight="3954.5"
                     /monoisotopic_mass="3952.0"
                     /core_sequence="ASGSFSSVASVNGCGRIGDQDLLADQCVVGVSRAALMPILP"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MTGFLVRQGRDRKSGFGA"
                     /leader_location="[3480:3534](-)"
                     /alternative_weights="3972.5"
                     /alternative_weights="3990.5"
                     /alternative_weights="4008.5"
                     /alternative_weights="4026.6"
     CDS             complement(3372..3521)
                     /gene="allorf_329941_330090"
                     /locus_tag="allorf_329941_330090"
                     /protein_id="allorf_329941_330090"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MCVKAETGRVASELRAGVFHLWRLLTGVAGSAIRIFWRISVSSAC
                     RGRP"
     CDS_motif       complement(3429..3521)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MCVKAETGRVASELRAGVFHLWRLLTGVAGS"
                     /locus_tag="allorf_329941_330090_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(3372..3428)
                     /prepeptide="core"
                     /locus_tag="allorf_329941_330090_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-5.30"
                     /molecular_weight="2021.4"
                     /monoisotopic_mass="2020.1"
                     /core_sequence="AIRIFWRISVSSACRGRP"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MCVKAETGRVASELRAGVFHLWRLLTGVAGS"
                     /leader_location="[3428:3521](-)"
                     /alternative_weights="2039.4"
                     /alternative_weights="2057.4"
     CDS             3536..3685
                     /gene="allorf_330105_330254"
                     /locus_tag="allorf_330105_330254"
                     /protein_id="allorf_330105_330254"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MSHSAGDVSDDCPISPYHDGAIAGHRGRWGSPVPRDPNRTHDDCG
                     MLLR"
     CDS_motif       3536..3610
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MSHSAGDVSDDCPISPYHDGAIAGH"
                     /locus_tag="allorf_330105_330254_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       3611..3685
                     /prepeptide="core"
                     /locus_tag="allorf_330105_330254_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.80"
                     /molecular_weight="2756.1"
                     /monoisotopic_mass="2754.4"
                     /core_sequence="RGRWGSPVPRDPNRTHDDCGMLLR"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MSHSAGDVSDDCPISPYHDGAIAGH"
                     /leader_location="[3535:3610](+)"
                     /alternative_weights="2774.1"
     gene            3691..6627
                     /locus_tag="KEM60_RS07350"
                     /old_locus_tag="KEM60_01528"
     CDS             3691..6627
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="KEM60_RS07350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="KEM60_01528"
                     /product="hypothetical protein"
                     /protein_id="WP_219106864.1"
                     /transl_table=11
                     /translation="MAGMRPDRGESADAGAPDQPMTRRARRHNAAESEPLTRAERMRRE
                     RMAMTESSGDLGATESSWPAQGTSYDSGISGYGSSSPSYGSSSSSPYSSGSLPTSGSPY
                     GTSTSDPTSAAYPSGSNPSSPYSSPTPSTPYTPSSYTSPATTYPSSGSTGSTTDTGSTT
                     GTGSSSYTSGSTYGAGSADKSSGTGLSSSPSSPYSSPTPSTPYTPSSYNSPATTYPSSG
                     STGSTTDTGSTTGTGSSGSSSYSSGSLPTSGSPYGASTPSTTPSAYTPSSPYTSPSYSS
                     GSSSSGIGTSPYSTGSSSPSTPATTSSPSSPLPGVGGAGSSSPYSSGPLPTSGSPYGAS
                     TPSTTPSAYTPSSPYTSPSYSSGSSSSGIGTSPYSTGSSSPSTPATTSSPSSPLPGVGG
                     AGSSSPYGGYSPTPSRSTAGTLPGVAGTPSASTPPGGFTATPTTGGLHSQALDPGPAVP
                     YNLPTNTMPKLRRTSTNALPTIDVSRPAELPVISAPRTTGLPVITVPGAPPLPVIGAQP
                     TVEMPVVSLPAFDKAHGDLDARSSMNAPVEGRSGRRRTDDDADEPLRGRSERSRSRRRS
                     ALDLDVENDEPVGRRSSRDRDASRDLEEFDEADEVDTTRDGRIAPWHLGLAALFLVLPW
                     IMHDALSPAEQQSLKAAQLPGFPIRKISITTDGILGTYHLLLHPLVSMVPPMIGARALS
                     VLGFAVTVSLACRIGRLVDGARGLVVAGVVTMMNPLLIGAAVQVKPYTLATAVATAAVL
                     RVLHIALDRKPVSQLWWVTWLGALAGYLHFFAFLAPVAAGMGMVVRRRSIRRLRHSSGM
                     WPALTAFCLMMPVGLIALVQIQQTSDSAPFSPISAVEMLAAALVRAPGLNSPLGHGIVL
                     LVLSAFGLGCLVMMAWSARRLRRPEESAVLTIAVSWLVLPSLGIVAASVLVPMLVPGYV
                     TASVPAVGLLAALSYRSARTTGIGTGRTVVLAYLIVMTVVSLASLVIW"
     gene            complement(6766..7512)
                     /locus_tag="KEM60_RS07355"
                     /old_locus_tag="KEM60_01529"
     CDS             complement(6766..7512)
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011773304.1"
                     /locus_tag="KEM60_RS07355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KEM60_01529"
                     /product="response regulator transcription factor"
                     /protein_id="WP_255574357.1"
                     /transl_table=11
                     /translation="MPTSDTLTRVVIVDDDSLVVEALRLFVESAQDLAVVGTASDGLGA
                     TKLVAEVKPDVVLMDMHMPYMDGVEATKRIHESHPDVCLLTLSSFATDRYVVAALRAGA
                     SGYLVKDTRPEEIIAAIRRAVAGEQTLSPEVVRHVVSAIREETRPTPPPAARFITEREM
                     DVIKLLTRGMSNKEIAENLFLTEATVKSHLARLIAKLGVRDRVQAVIRAYEWNIADLGL
                     DDCTRSGRAFSATRDVTRGCHRAGRR"
     misc_feature    complement(7522..7539)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 16.32"
                     /tool="antismash"
     misc_feature    complement(7553..7567)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 19.91"
                     /tool="antismash"
     misc_feature    complement(7555..7573)
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 19.72"
                     /tool="antismash"
     gene            7891..9045
                     /locus_tag="KEM60_RS07360"
                     /old_locus_tag="KEM60_01531"
     CDS             7891..9045
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF019350.4"
                     /locus_tag="KEM60_RS07360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KEM60_01531"
                     /product="sensor histidine kinase"
                     /protein_id="WP_219106865.1"
                     /transl_table=11
                     /translation="MNRLNPIDAAWTLRVFLLGGVLLSFISGADGSIGDICYSATTHAI
                     PAVAVFRADIASLLFIPLLIISAPLDTAFAILLPLLILMALVANTQPLRRVAGLATAAV
                     AWLAVELGFGQLDFSANITPLFLISVGITLQGVLLRLSILQRRKQQHELAEAMKRAEAA
                     SAGERRRLAGELHDIVAHDLTVLTMLSTMGQTLDDTEKIKDHLSRMELTSRSALADLRR
                     LLGALERTEVPPVSLGTSTTRPDIRAVVDSGIEELTRLNFPTSLTCRGELDSIPRSVQH
                     ALRRSINEMFANVTKYAEPGSPVDIVLVLTTDGVTLRITNVPSPIDRRTDSGGMGLGLS
                     HLQEQAESFNGSFQAGLEGHRWISELYIPLQPNETDDGRQSSPR"
     gene            9276..10004
                     /locus_tag="KEM60_RS07365"
                     /old_locus_tag="KEM60_01532"
     CDS             9276..10004
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012235.4"
                     /locus_tag="KEM60_RS07365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KEM60_01532"
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="WP_219106866.1"
                     /transl_table=11
                     /translation="MDSGEIRLKNLSFSYAGEPRAVLDDINMSIGSGDLVAVVGQSASG
                     KSTLGKVICGLYEAGREAVEIGGHPLGDYDRDALRRQIGYVPQDVTLHNGTILENLAMG
                     SDLDEAEIERRCRRLDFLDFIERLPMGYRTMVANLGANFSGSQRQRLAIARVLLRSPQI
                     IVFGEATSALDQLNEQRVNRVLRSLGCTRIIIAHRLETVRGADTIYVIEDGCVVEQGTH
                     NGLLESNGVYSLLYRQGVPA"
     gene            10001..12703
                     /locus_tag="KEM60_RS07370"
                     /old_locus_tag="KEM60_01533"
     CDS             10001..12703
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF024964.4"
                     /locus_tag="KEM60_RS07370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KEM60_01533"
                     /product="DUF4135 domain-containing protein"
                     /protein_id="WP_219106867.1"
                     /sec_met_domain="DUF4135 (E-value: 9.7e-56, bitscore:
                     183.9, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 6.5e-17, bitscore:
                     55.7, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAIGTPLTPVDVDAEPIRIQTAFAPLLDAVTDRVTASRAPRYVL
                     PEGVAAGLRAVIRTDVTMVWIRILVEEFHRFREELGLPDSPASTTALRRFHEALLDGDF
                     IDRVIGAWPTAVGLVERRGRWHRDAAEEMWAAWLADRDRLVAAGMVSADFEPVAARFGA
                     GDSHHQARTVIILTGADDSRIVFKPRAPETDLMLVDLLDLLGRTFGVDMSRCAPRSLAG
                     TQGCWQEFIASHEPVNPQEVHDYFLRFGLLAGLSGAIGAGDLHHENVILRGAYPCVVDS
                     ETILQARFMPLDGRLASRMLNAAQRCPGATLMLPARVRRGAFDIFISALGVPWVQVSDK
                     ETFDIVDDGTDAVRLGRIKITMELDGNVVRLGGERVDHLDHLDTVIEGYLLAQATLTEH
                     LDEYVAALESARNALFRIVLRPTQVYGTFVDASVHPSALADSVERRRVLGLLKDVDYND
                     EGRIGARERADLEVLDIPAFHCFGGSTRLVSGGQELSGDYFVLSPVDSALRSLHEFCER
                     PAAYHRFQLETSLNELAAGQDRPYPFAMLRSAFVAGPQATIDQVFHVLDAAGERGMNEQ
                     GVEAISWLSHLGHDGLETYEIDQTMTFHDTDGIAAMLSTRHPGTALAAQSLAALSLVQV
                     PTGTTRCSVLAGPASTLFIRGRAVLPAPPEAPTESTELDLMVGTAGLLLAAARMAEPDL
                     AWIARARDHLTTWTPQCAWKRPWSDLAHGMIGVEWARFRAAHTLGEDTGRLAAGLIAGL
                     EHAVEDSMYGAAWCSGAAGGLVVLADLHESGHDVPADLTRRLTRRVATGGPGVVDVSVC
                     HGVAGRIQALLRAEEGRLITDGRERAQELWRRSAETARTEGIQTGAPGRTAILEYFLGW
                     AGVADTAHRLLHGAGLFDAVSLIPPTKEI"
     gene            12705..13583
                     /locus_tag="KEM60_RS16510"
                     /pseudo=""
     CDS             12705..13583
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012235.4"
                     /locus_tag="KEM60_RS16510"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="ABC transporter ATP-binding protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MAITIDHVSLDYGEFALKDVTFDVQPGEVVGFLGPNGSGKSTTLR
                     VLLGLERPDSGTVLIAGQR"
     gene            13589..14344
                     /locus_tag="KEM60_RS07385"
                     /old_locus_tag="KEM60_01536"
     CDS             13589..14344
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="KEM60_RS07385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="KEM60_01536"
                     /product="hypothetical protein"
                     /protein_id="WP_219106870.1"
                     /transl_table=11
                     /translation="MRTLRTELRKVVAYRLPLFVAVGALLLVGLWDVTILARGQSGLRA
                     MDSSLAFSGIVLPTAWFIIPMLLVGADTCEGTLWPALHSRPGTTRVLMGKAVAAVVVAV
                     VTALLAALMLAGLTLVTSHGAPTVEVLPAVIGRLLIQAMLCTVIAFSIYVLTGYQGASW
                     IILGLLVWIHFVERVLSSALPGNAGMLGMPFRLVDFWIRGKWSATMPQLEMFGFGPLAV
                     YTAALAALAAGSFIFFSDSSGRTWGRKRW"
     gene            14349..15191
                     /locus_tag="KEM60_RS07390"
                     /old_locus_tag="KEM60_01537"
     CDS             14349..15191
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="KEM60_RS07390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="KEM60_01537"
                     /product="hypothetical protein"
                     /protein_id="WP_219106871.1"
                     /transl_table=11
                     /translation="MSFTLADGRGADRSPTVESTPWATTLRWMRTLVVKNGLAPILLRS
                     VLVPMLLSFAGALFMMLGPVPIRPDAAGGIPDRDVVFLFLGYMLLGQLVVIVSGAWLHL
                     RDVLSRSLGGIYTAVPDRRAVTLGTALVAAVVGALGALASVLTGVVTFMVVAGGDLAAT
                     MSSPRVMQMLLGLPFGAAMLSVIAVAVAVLVRQPIAAACLLVIWATYGEDAVGLIPGVG
                     PVVKLLLPITNGQAVAGAPGVQGISGSSLVAGLWMAVLAAISVVVAVVVERRRRGWVS"
     gene            15329..15958
                     /locus_tag="KEM60_RS07395"
                     /old_locus_tag="KEM60_01538"
     CDS             15329..15958
                     /GO_function="GO:0070273 - phosphatidylinositol-4-phosphate
                     binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF017530.4"
                     /locus_tag="KEM60_RS07395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KEM60_01538"
                     /product="GPP34 family phosphoprotein"
                     /protein_id="WP_219106872.1"
                     /transl_table=11
                     /translation="MLICEDVMILLAEPRGMIENWDARRQWSLTAGALCDLEELGAIAI
                     EGKQVRVLSEQATGHAALETILTRIVDRRDRKLPSILRDSAACPLEDIIEGLSARGVLE
                     LKSKSRFGLLPSRYTVTDSTVENNLRAAMTNTLHGRGNRHHLSVLAIINSVEVVHQALK
                     HEAAGVKDREISALLEDVKDSSTMMSALRSSTRGIGSALPAIAGGM"
     misc_feature    complement(15332..15345)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 19.21"
                     /tool="antismash"
     gene            complement(16061..16462)
                     /locus_tag="KEM60_RS07400"
                     /old_locus_tag="KEM60_01539"
     CDS             complement(16061..16462)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF012422.4"
                     /locus_tag="KEM60_RS07400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KEM60_01539"
                     /product="response regulator transcription factor"
                     /protein_id="WP_219106873.1"
                     /transl_table=11
                     /translation="MRISSDKRLPNAASPTALKARSGREGAGDVRRTVMVEQTLSPGVI
                     AHVVDAIREDKRSAPPMAARFITGREMDVIKLLGRGMSNRETADALGLTEATVKSYLAR
                     LIAKLGVRDRVQAIIRAHEWNIAELGLDD"
     gene            16461..16922
                     /locus_tag="KEM60_RS07405"
                     /old_locus_tag="KEM60_01540"
     CDS             16461..16922
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0046983 - protein dimerization activity
                     [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF019350.4"
                     /locus_tag="KEM60_RS07405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KEM60_01540"
                     /product="histidine kinase"
                     /protein_id="WP_219106874.1"
                     /transl_table=11
                     /translation="MALVANTQPLKWVIALAVASVAWGTVASAYGVFRLDGGIAALLPI
                     LAGVVLQGAVLRSSLLPRRLERNELAAAVTRAETARAAERRRLAGELHDIVAHDLTILT
                     MLSATGQNLDDSGRYKPRSPAWYRHPGRPSPNSASSSTCSNERRHLRSV"
     gene            17021..17374
                     /locus_tag="KEM60_RS07410"
     CDS             17021..17374
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="KEM60_RS07410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_219106875.1"
                     /transl_table=11
                     /translation="MVPRSVQHGLRRSISGMLANAAKYAEPGTPVDIDLALTADEVALR
                     VVNTSSSTGQIHGPERIGLGLNNLQEQAECFNGTFHAELRQHRWVSELRVPLQPHAAEA
                     VRNLSTWPAEQMS"
     gene            <17433..17579
                     /locus_tag="KEM60_RS16515"
                     /pseudo=""
     CDS             <17433..17579
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012949561.1"
                     /locus_tag="KEM60_RS16515"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="IS5/IS1182 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="TCRAPVECANALLKSSFKALRRITLCPWRIGHITTVALILLTTNG
                     GCW"
     gene            complement(17764..19533)
                     /locus_tag="KEM60_RS07415"
                     /old_locus_tag="KEM60_01543"
     CDS             complement(17764..19533)
                     /EC_number="4.2.1.53"
                     /GO_function="GO:0050151 - oleate hydratase activity
                     [Evidence IEA]"
                     /GO_function="GO:0071949 - FAD binding [Evidence IEA]"
                     /GO_process="GO:0006631 - fatty acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002856600.1"
                     /locus_tag="KEM60_RS07415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KEM60_01543"
                     /product="oleate hydratase"
                     /protein_id="WP_219106876.1"
                     /transl_table=11
                     /translation="MYYSSGNYEAFARPRKSHRADTASAHLVGAGLASLAAAGFLIRDA
                     QVDPHRITILEASPLSGGACDGIVDPGKGFLIRGGREMEEHFECLWDLFRSIPSLETPG
                     ASVLDEFSWLNKDDPNYSLMRATKDQGRDGRTDGRFDLTTRAQLDIGRLFFTRDEDLAD
                     LKITDVLGRDFLDSTFWLYWRTMFAFEEWHSALEMKLYLQRFIHHIGGLPDFTALKFTK
                     YNQYESLILPLVTWLQDQGVTFQYDTRVTNVLVEKTAVPGDPTAPLRKMARRIEWTRNG
                     FPGGIDLTENDVVFVTNGSCVENSTWGDHHQAPALDARIHDDGIWSLWKNMARQDESFG
                     HPEKFCSDPQLTNWESATLTTLDDRIPPYLEKICQRNPFEGRVTTGGIVTVRDSSWMMS
                     WTINRQPHFAAQPADKLVIWIYGLFTDRPGDYVKKPMRDCTGEEITREFLYHIGVPPAQ
                     IDEMAATSAVCMPCMMPFITAFFMPRSRADRPDVVPAGSVNLAFLGQFAHTDRDTVFTT
                     EYSVRTGMEAVYTLFDVDRGVPEVWGSVYDIRVLLTAASRLRDGRPLWAPTVIRRGLDR
                     TVLGPLLRSTGVL"
     gene            19730..20458
                     /locus_tag="KEM60_RS07420"
                     /old_locus_tag="KEM60_01544"
     CDS             19730..20458
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1215: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF036523.4"
                     /locus_tag="KEM60_RS07420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KEM60_01544"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_219106877.1"
                     /transl_table=11
                     /translation="MPTSGPPETHPAPPTEGRRERNKRLKAEAILAAAEDLFRHHGYTA
                     VTTQQIAEAAQVSNGSLFRFAGTKADLLIRVMESRLRLGREQGLQMARSGADPVEAIIA
                     LLHPIAETGMPHPEVVVAYQRELLFAEAPERGAELDSVEAMEAAIREVLTIERPGYDEQ
                     TVHFAAFTIYSTIYMDLVRVSVGRASAQDLPRRLRATIRTLLDTLIPAKEGMVSAADPA
                     RVPQRSSTGSAPGQRSTVRT"
     gene            complement(20434..21399)
                     /locus_tag="KEM60_RS07425"
                     /old_locus_tag="KEM60_01545"
     CDS             complement(20434..21399)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013986.4"
                     /locus_tag="KEM60_RS07425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KEM60_01545"
                     /product="BadF/BadG/BcrA/BcrD ATPase family protein"
                     /protein_id="WP_219106878.1"
                     /transl_table=11
                     /translation="MSAPSEAPPTSYAVADCGGTHTRLEIWHGTTPALTETFGSANTAS
                     RSADEALDVYSALIARVAEHHVTATYIATAGFDDTSADTLAAQFRSLAITHQYDGTIHL
                     VNDVAPLLFSGAPGTETVAAIIGTGSAFWTRDATDSLTRVGGVEWLASDEGAAVDLGKR
                     ALIAMVRAADGRGPATTITTHANLNDADTLHLARTLGETAHPKQHLAGLAPAVTTAWTD
                     DHDPVATEIITAAVADVEAALAASARFLSHPAAASWLFCGGLVSGSDDYQQLILAAATR
                     ASGGATDLRVVQNALDLLRSFAAHGWANRVGERYVRTVER"
     misc_feature    21486..21502
                     /note="TFBS match to NtrC, Nitrogen regulatory protein C,
                     confidence: medium, score: 23.38"
                     /tool="antismash"
     gene            21558..21989
                     /locus_tag="KEM60_RS07430"
                     /old_locus_tag="KEM60_01546"
     CDS             21558..21989
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018188911.1"
                     /locus_tag="KEM60_RS07430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KEM60_01546"
                     /product="DoxX family membrane protein"
                     /protein_id="WP_219106879.1"
                     /transl_table=11
                     /translation="MKPYVRLLARILLGVFLMSAGYSHMTSARMEFQAQVPDWFPMDKD
                     LVVILSGIVEMTLGAALISGFRKQIVGLAAAAFFIAIFPGNIAQFIEGKNAFGLDSDRA
                     RAIRLLFQPLLVLWALWATDAFPVITQWWKSRKAGASQS"
ORIGIN
        1 ccgcgcaacg gttcctcgct caacagcacg agattgagac cttcacccaa gaaacactgg
       61 ccgggtcatt gcgctccatt gttggttcgc tgactgtgga gcaaattatc cgcgaccgag
      121 cggcttttgc tcagcgcgtc gccgacgagt ccgaaacgtc cctcactggg caggggcttg
      181 tccttgatac cttccaaatt caggacatca ccgacgacgg cagctacctg catgacctgg
      241 gtcgccccga agctgcccgc aacggtcaga ccgcagccat cgccgaagcc aacgcccgtc
      301 aagctgccga acaagcccgc atcgccgctg aacagcagat cgccgactcc cagcgtgcgc
      361 tgagcctgcg acaggcagag atcaaagccg aaacggacgc ggccagcgca aaagctgcgg
      421 cctccggccc gctcgcccaa gccgaacggg accaggccgt cctctccgag aaggaaaagg
      481 tcgccgtccg tcaggccgca ttgaaagaac ggcaactcga cactgaggta cgtcgtcccg
      541 ccgacgccga acggtaccgc gtcgaacagg acgctgctgc gcgtcgtaac gccgcgatcg
      601 ctgaagctga agcgcggaaa gcagcctcca tcgcggcggc cgaagccgat gcagaaaaag
      661 cccgcctcac cggtgaagcc gagaaatctc gccgtaccgc actggccgaa gctgaagcca
      721 tcgaaggtgc ccgccgaggt gaggcggaga aagcccgccg caccgctgaa gccgacgcca
      781 cccgcgctga aggtgacgcc caggcagcgg cgacgctggc catcggccat gctgaagccg
      841 aagcgatgaa cgcacgcgcc gaagcgttcg cccgctacaa cgaagccgcc gtgctgcaga
      901 tgctcgtcga agtgcttccg caagtcgctc gtgaagtcgc ggcaccaatg gcagccatcg
      961 acaaactcac cgtggtctcc acggacgggg ctgccgcttt gcccaagcag gtcactgaca
     1021 acctcgtcca gaccatggca ctgctgaaaa acaccaccgg agtcgacttg gagtctctgg
     1081 tcaagaaata cggccagtca tcgccgaacc acggagacgc cgcatccatc tcgtgaccgg
     1141 acagcgcctc ctggatgagc tgacatgaga cggcatgagc tggcgagaca gtggtgggcg
     1201 gccggagcaa tctccggtcg ccccccacga cctttgcgat ctgtccctag gcgccgacga
     1261 ccctcaacaa ccaaagagaa gcggccccgc ggcgaccttt cacccgtgga tcggcaggtc
     1321 acctttcggc gcgtcataca cctcacggtc cagcaggccc tctcgagccg cgaccaccac
     1381 cggcaccagc gcctgaccag ccacattggt ggcggtacgc atcatgtcca agatcggatc
     1441 gatggccaac aacaacccgg ccccggccaa tggcaaaccc aacgtcgaca aggtcaacgt
     1501 caacatgacg atggcgccgg tcaggccggc cgtggctgcg gaaccgacaa ccgagaccaa
     1561 cacgatcaag gcaagctgtg gcactgacaa gtgcatccca aacacctcag ccacaaaaat
     1621 cgacgccaac gctgggtaga ttgccgcgca accgtccatc tttgaggtcg ccccaaaagg
     1681 tacggcgaac gccgcgtaat ccttcggcac gcccagtcga tccacggtga cttcttgggt
     1741 caacggcatc gtgcccactg aggatcggga cacaaacgcc aactggatcg ctggccacgc
     1801 acccgcgaag aagcgcaccg gattgagttt tgcagcgaac atcagcactg ccgggtagag
     1861 caccaacaac accaggaagc atccgacgta cacatcgacg gcaaacgtgg ctagcggggc
     1921 cagcaaatcc cagccatacg tcgcgacagc cttaccgatc aacccgagcg tccccagcgg
     1981 agccaacaga atcacccacc acaacgcttt ctgggtgatc tccaaagcag catcaacgac
     2041 cgcaaggaac ggttcagctt tgtctccgac ctgcaccgca gcgagaccga cgaccacgcc
     2101 gaggaagacg atctgcaaga cgttgccctg cacaaacgca cccaccgggt tggtcgggat
     2161 gatgccggtg aggaagtccg tccacccccc ggctttctcc ggggccttcg ctgcccccag
     2221 atcaaggctg acgccacgcc ccggatgggt gagcaaacct aacgccagac cgatcagtga
     2281 cgacgccaac cccgtgatgg cgaaccacac caacgttttt ccagccagac gagccgcatt
     2341 ggtgacaccg cgcaggtgag caatgctgct gaccactgcc gtgaaaacca gcggtgggac
     2401 agcaagtttg aggagttgca caaacaacga gccgatggtg cccaaggtcg ttgccaacca
     2461 ggtgatctga gcttcccggg cgagatagcc cagcacaacg cccagcgcca gcgcgacgag
     2521 cacctgggtg gtgtaggaga gtcggaatcg acgtcgcgat ggtggagaca ggtcgtcccc
     2581 gccagtgtca ggagctgcga tgtcagatga tgcggtggcg gacatgtttt tccttgaggt
     2641 ctgggtgcgg gtcaggtggg gctggtcagc ccagacagat acacgcagcc tgacgacgca
     2701 ggtcgacgta cctgcgttcg gtcaggttcc agatgttggc cacgaaacgt gaacttacgc
     2761 ccctcgccgg gtattcccca aagagcccac gcacccctac tcgggtgctg cctgccgcga
     2821 caggacaccc caccccgggt ctcaccgcac cgatccccgt ccgagacgat ggtctcgccg
     2881 gtcgcaaaga tcccggcacg gcgtccttgc caccaccggt ggggacctta ctgaatcgtt
     2941 catggacacc cagcgaagga gaacgccatg tcattcctcg aagaattcag caaagtcgcc
     3001 caaaaagccc tgcaagaagc cgaggtcgtc accgccaagg cacgtcaggc agcaggggcg
     3061 gccgccgacg cccatcgcga caaaattgac gattacatcg gcaaagctgg aacgttcatc
     3121 gacgagaaga ccgaagggaa gtatcaccag caggtcatta aagcgcagga cgtggcaggg
     3181 aagggagtcg acatcgtggc ccagcagaag tccgcgacca tcccggaccg acccgcagcg
     3241 cagcccaaag atgacagcgc cgacaccccg cagacccccc gtgacgcagc gccgaaagca
     3301 ccagctgaac ccgaccggga agacggatct cctactgcct gaaggggcct cacgtcacgg
     3361 caggatcggc atcagggccg cccgcgacac gccgacgaca cactgatccg ccaaaagatc
     3421 ctgatcgccg atcctgccac acccgttaac agacgccaca gatgaaaaac tcccgctcgc
     3481 agctccgaag ccactcttcc ggtctctgcc ttgacgcaca aggaagcccg tcatcttgtc
     3541 tcattccgca ggtgatgtat cggacgactg tcctattagc ccgtatcatg acggggcgat
     3601 agccggtcat cgcggtcggt ggggatcccc agtcccgcgc gatccgaacc ggacccacga
     3661 cgactgcggg atgctgctga ggtgatgcag atggcgggga tgcgacccga ccggggagaa
     3721 tccgccgatg cgggcgctcc cgaccagccc atgacacgac gagcccggcg ccacaacgcc
     3781 gcggagtcag aaccgctcac cagagctgag cggatgcgcc gagaacgcat ggccatgacc
     3841 gaatcgtccg gggacctcgg cgccaccgaa tcctcatggc cggctcaggg gacgtcgtac
     3901 gactccggca tctccgggta tggatcgagt tctccttcct acgggtcgag cagcagctct
     3961 ccatacagct ccggatcgct ccccaccagc gggtccccgt acggcaccag cacgtccgac
     4021 cccacttcgg ctgcatatcc gagcggcagc aacccgagca gcccctacag cagccccaca
     4081 cccagcacgc cgtacacacc cagctcctat accagccccg ccaccaccta ccccagcagc
     4141 ggcagcactg ggagcaccac tgacactggg agcaccacgg gcacaggcag ctcctcgtac
     4201 acctctgggt ctacctacgg cgctggcagc gcggataaga gtagcggcac cggactcagc
     4261 agcagcccga gtagccccta cagcagcccc acacccagca cgccgtacac acccagctcc
     4321 tacaacagcc ccgccaccac ctaccccagc agcggcagca ctggcagtac cactgacact
     4381 gggagcacca cgggcactgg cagtagtggc agttcgtcgt acagctccgg atcactgccc
     4441 accagcggat ccccgtacgg cgcgagcaca cccagcacca ccccctcggc gtacaccccc
     4501 agcagcccct acaccagccc cagctacagc agcggaagct cctccagtgg catcggcacc
     4561 tccccctact ccacgggaag cagttccccg tcaacacccg ccaccacaag cagccccagc
     4621 tccccgctgc ccggcgtcgg cggtgcggga agcagctcac cgtacagctc cggaccactg
     4681 cccaccagcg gatccccgta cggcgcgagc acacccagca ccaccccctc ggcgtacacc
     4741 cccagcagtc cctacaccag ccccagctac agcagcggaa gctcctccag cggcatcggc
     4801 acctccccct actccacggg aagcagttcc ccgtcaacac ccgccaccac aagcagcccc
     4861 agctccccgc tgcccggcgt cggcggcgcg ggaagcagct ccccgtacgg cggatacagc
     4921 cctacaccgt cacggagtac ggccgggacc ttacctggag tagcaggaac cccgagcgcc
     4981 tcaactccgc ccggaggctt caccgccacc cccactaccg gcgggttgca ctcccaggcg
     5041 ttggatcccg gcccggcggt cccctataac ttgcccacga acacgatgcc gaaactgagg
     5101 cggacgtcga caaacgccct gcccactatc gatgtctccc gaccagctga actcccagtg
     5161 atcagcgcgc ctcgtacgac gggattaccg gtaatcacgg ttcccggggc gcccccgctg
     5221 cccgtcatcg gcgcccagcc cacagtggag atgccagtag tgtcgctacc cgcttttgac
     5281 aaggcgcatg gcgatctgga tgcccgttct tccatgaacg cccccgtcga aggcaggtct
     5341 gggcgtcgcc gtacggacga cgacgcggac gaaccattgc ggggccggtc cgaacggtcc
     5401 cgtagtcgcc gacggtctgc tttggatctg gatgtcgaaa acgatgagcc agtgggtcgc
     5461 cggagcagcc gagaccgtga cgctagccgg gatctggagg agttcgacga ggcagacgag
     5521 gttgacacca cgcgcgacgg tcgcattgcg ccatggcatt tagggctagc tgcgcttttc
     5581 ctggtcttgc cgtggatcat gcacgacgcg ctgtcaccag cggagcagca aagcttgaaa
     5641 gctgctcaac tcccaggctt ccccatccgc aagatttcca tcaccactga cggcatcctg
     5701 ggcacctacc acctattgct gcatccgctg gtgtcgatgg tgccgccgat gatcggggca
     5761 cgagccctgt cagtcctggg ttttgcggtc accgtgagtt tggcctgccg gatcggcaga
     5821 ctcgttgacg gggccagagg attggtggtg gccggcgtgg tcaccatgat gaatccgctg
     5881 ctgattggcg cagccgtgca ggtcaagcca tataccttag cgactgcggt ggccacggca
     5941 gccgtgctgc gggtgttgca catcgccttg gaccgtaaac cggtctcaca gttgtggtgg
     6001 gtgacctggc taggggcgct agcaggctat ttgcatttct ttgccttttt ggccccggtc
     6061 gcagcgggga tgggcatggt ggtccgacga cggtcgatac gtcgactacg gcattcgtcg
     6121 ggaatgtggc cagcgttgac ggctttctgc ctgatgatgc cggtgggttt gatcgcttta
     6181 gtgcagatcc agcagacctc cgattcggcg ccgttctcgc cgatatcagc ggtggaaatg
     6241 ctcgcagccg ctctggtccg agcgcccggg ttgaactcgc cgctgggcca cgggattgtc
     6301 ttgctggtct tgtccgcttt cgggctggga tgcctggtga tgatggcgtg gtctgcgcgc
     6361 cggttgcgcc gccctgaaga gtccgcggtc ttgacgattg cagtgtcctg gctggtgctg
     6421 ccaagcctag gtatcgtggc cgcttcagtg ctggtgccga tgctggtgcc ggggtatgtg
     6481 acggcgtcag tcccggcggt gggtttgtta gcggcgctgt cgtaccggtc ggcgcgcacc
     6541 actggcattg ggaccgggcg cactgtggtc ctggcctact tgatagtgat gactgtggtg
     6601 agcttggcgt cgctggtgat ctggtagtta tcgacatcac caggaggggg cgccccgcgc
     6661 agggacgccc cctcctcgca tacccagacc tcgttcgttc aggctgagta gggcaggatc
     6721 aagagctgac gtctgctagc accacctgcc accaccacac cgccgtcacc gacgtccagc
     6781 cctgtgacag cccctcgtca cgtctctcgt ggcggagaag gcgcgaccgc tccgggtgca
     6841 gtcgtcaaga ccaaggtcgg cgatattcca ttcgtaggcc cggatgaccg cctggacacg
     6901 gtcacggacg ccgagtttgg caatcagccg agcgaggtgg gatttcaccg ttgcttcggt
     6961 gagaaacagg ttttccgcaa tctctttgtt gctcataccc cgagtgagga gcttgatgac
     7021 gtccatctcc cgttcggtga tgaaccgagc tgcgggagga ggtgtgggcc gcgtctcctc
     7081 ccgaatcgcg ctgactacat ggcggacgac ttcaggtgac agggtctgct caccagcgac
     7141 ggcacgacgg atagccgcaa tgatttcttc cggccgcgtg tccttgacca ggtatcccga
     7201 ggccccagca cgcagcgcag cgacgacata acggtcagtg gcgaaggacg acaaggtgag
     7261 gaggcagacg tcggggtgcg actcgtggat acgtttcgta gcctccacac cgtccatgta
     7321 cggcatgtgc atgtccataa ggaccacatc tggcttcact tcggcgacga gtttggtggc
     7381 gcccaggccg tctgaagcgg tacctaccac tgctaggtct tgggcggact ccacgaagag
     7441 tcgaagcgct tcaacgacga gcgaatcatc gtccacgatg acgacacggg tcagagtgtc
     7501 agaggtaggc acacagggaa tgtaacgtac ctctcacaag cgtgacagca acttcgcata
     7561 atgggtacaa cagccaaatt ggacatgtgg caagctggag actgcctccc aagcgtctcg
     7621 atctccatct tgaaggactt gcatgcacac cacgcgccga gccctcactg tcagcgcctt
     7681 tcccagcatg ggtctcatct cgttcggggc ggcccccatg cacactactt cgctcctggc
     7741 ggcaccgacg gagcacccat tgacagggat cgaggcctca caccagggca tcaacagagg
     7801 attaatggcg ccacttaata tcaaactttc cgcggctact cctcacatcc atcagatctc
     7861 tcgttgacaa cgatggcaaa aaccctgacc atgaaccgac tcaatcctat tgacgctgct
     7921 tggactctcc gagtattcct ccttgggggg gtgctcttgt ccttcatcag tggggctgac
     7981 ggtagcatcg gcgatatctg ctatagcgcc accacccacg ccatccctgc agtggcagtg
     8041 ttccgtgcgg atatcgcgag ccttttgttt ataccccttt taattattag cgcacccctc
     8101 gacacagcat ttgcgattct cttgccgctg ctgatcctca tggcattggt cgccaacacc
     8161 cagcctctcc gacgagtcgc aggcctcgcc actgccgctg tcgcatggtt ggcagtggag
     8221 ttaggttttg ggcagcttga tttttccgcc aacatcaccc cactgtttct tatctcggtg
     8281 ggaattacac tccaaggcgt cctcctccgt ttatccatcc tgcaacggcg gaaacaacaa
     8341 cacgaactcg cagaagcgat gaagcgcgcc gaggctgcca gcgctgggga acgacgacgc
     8401 ctcgccggcg aattacacga catcgtcgcg cacgatctca ccgtactcac gatgctctcc
     8461 accatgggac agactctcga cgacacagag aagatcaaag atcatctcag ccgaatggaa
     8521 ttaacgtctc ggtctgccct cgcagatctt cggcggctgc tcggtgcact cgaacgcacg
     8581 gaggtacctc cggtcagcct aggaacttcc accacccggc ccgacatccg cgccgtagtg
     8641 gactctggca tcgaggaact cacccgcctc aattttccca cgtcactcac atgcagggga
     8701 gagctagatt ccattccacg ttcagtccaa cacgcactgc ggcgcagcat taacgaaatg
     8761 ttcgctaacg tcacgaagta cgcagagcca ggtagccctg tcgacattgt cctcgtcctc
     8821 acaacggatg gagtcaccct gcggatcacc aatgtcccat caccgataga tcgccgcact
     8881 gattccggag gaatgggact aggcctcagc cacctccaag aacaggcaga gtcgttcaat
     8941 ggctcattcc aggctggcct tgaggggcat cgatggatat ccgaactcta tattccgttg
     9001 caacccaacg agacggatga cggccgtcag tcaagtcccc ggtagtcggg taacggagaa
     9061 tatcgatctc acgtcctgac tgatcatctc gacgagttgg aatcgggtcc tcgccgaacg
     9121 cgacatcgtg acctggatcc agagctggaa ccccaatccg gaaccgttcg tatggaccaa
     9181 aatcgccgac gctacgctcg tactcccgct acctcgaaaa gctcgaggac atcctcggca
     9241 ccgaggtcga gtcgaccagc gggtcgcgca ccgagttgga cagcggtgag atacgactca
     9301 agaacctgtc cttcagctac gccggtgagc cgcgtgccgt gctggacgac atcaacatgt
     9361 ccatcggctc gggtgacctc gtcgccgtcg tgggccaatc tgcttccggc aagagcaccc
     9421 ttggcaaggt catctgtggc ctgtacgagg ctggtcggga ggcggtcgag atcggtgggc
     9481 atcccctcgg cgactacgac cgtgacgccc tgcgccgcca gattggttac gtgccacagg
     9541 acgtcacgct gcacaacggg acgatcctcg agaacctcgc tatgggcagc gacctcgacg
     9601 aggccgagat cgaacgtcgc tgccgccggc tcgacttcct cgacttcatc gagcgcctcc
     9661 ccatggggta ccgcacgatg gtggccaatc tcggagccaa cttctccggg agccagcgtc
     9721 agcgtctcgc gatcgccagg gtgctcctgc ggtctcctca gatcatcgtc ttcggcgagg
     9781 cgaccagcgc tctcgatcag ctcaacgagc agcgcgtcaa tcgtgtcctg cgcagcctgg
     9841 gttgtacgcg gatcatcatc gcccaccgcc ttgagacggt gcgcggcgcc gacaccatct
     9901 acgtcatcga agacggatgc gtcgtggagc aaggcactca caacggtctt ctcgagtcca
     9961 atggggtgta ttcgctcctc taccgccagg gagtccccgc atgaccgcca tcggcacccc
    10021 gctcacccct gtcgatgtcg acgctgaacc catccggatc caaacggcgt ttgcgccgct
    10081 gctggatgcg gtgaccgacc gggtcaccgc atccagagcg cctcggtacg tgctgccgga
    10141 aggcgtcgca gccggactga gggctgtgat ccgcaccgat gtgacgatgg tgtggatccg
    10201 catcctcgtc gaggagttcc accgtttccg agaggaactc ggccttccgg attctccagc
    10261 gtccaccacg gcgctccgcc gtttccacga ggcgctcctc gacggcgact tcattgaccg
    10321 agtgatcggt gcctggccga ccgcggtcgg gctcgtcgaa cgccgaggcc gctggcaccg
    10381 cgacgccgcc gaggagatgt gggcggcgtg gcttgccgac cgggaccggc tcgtcgccgc
    10441 gggcatggtc tccgccgatt tcgagccggt cgccgcacgg ttcggtgcgg gcgacagcca
    10501 ccaccaggct cgcaccgtca ttatcctcac cggggccgac gactcgagga tcgtcttcaa
    10561 gccccgcgcc cccgagacgg acctcatgct cgtcgacctg ttggacctgc tcgggcgaac
    10621 gttcggcgtg gacatgagcc ggtgcgcccc ccgttccctg gcgggaacgc aagggtgctg
    10681 gcaggagttc atcgcctctc acgaaccggt gaacccccag gaggtgcacg actacttcct
    10741 gcggttcggc ctgctcgcag gtctctctgg cgccatcggc gccggagacc tgcaccacga
    10801 gaacgtcatc ctgcgtggtg catacccgtg tgtcgtcgac agcgagacca tcctccaggc
    10861 acgtttcatg ccactcgatg gacgcctcgc cagcaggatg ctgaacgccg cgcaacgctg
    10921 ccccggggcg acactcatgt tgcccgcccg ggtccgcagg ggtgcgttcg acatcttcat
    10981 cagcgccctc ggagtaccgt gggtgcaggt ctccgataag gagaccttcg acatcgtcga
    11041 cgacggtacg gacgcagtgc gcctgggccg gatcaagatc accatggaac tcgacggcaa
    11101 cgtcgtccgc ctcggcggtg agcgggtcga ccacctcgac cacctggaca ccgtaatcga
    11161 ggggtacctg ctcgcgcagg cgacgctcac cgagcacctc gacgagtacg tcgccgccct
    11221 cgagtcggcg cgcaacgccc tcttccgcat cgtcctgcgc cccacacagg tgtatggcac
    11281 cttcgtcgac gcgtccgtgc atccttcggc gctcgcggat tccgtcgaga ggcggcgtgt
    11341 gctggggctt ctgaaggacg tcgattacaa cgacgaggga cgcatcggtg cacgtgagcg
    11401 cgccgacctg gaggttctcg acattcccgc gttccactgc ttcggcggct ccacgcgcct
    11461 cgttagcggg ggacaggagt tgtcggggga ctacttcgtg ctctcaccgg ttgactccgc
    11521 tctgcgcagc ctgcatgagt tctgcgaacg ccctgcggcg tatcaccggt tccagctcga
    11581 gacgtccttg aacgagttgg ctgccggtca ggaccgcccc tatcccttcg cgatgttgcg
    11641 gtccgcgttc gtcgcggggc cacaggcgac aatcgatcag gtcttccacg ttctcgacgc
    11701 cgccggggag cgcggcatga acgagcaagg cgtcgaggcg atctcctggc tctcgcacct
    11761 cggccacgac ggcctggaga cctacgagat cgaccagacc atgaccttcc acgacaccga
    11821 cggcatcgcg gccatgttgt cgacgcgaca tcctggaacg gctctcgccg cacagtccct
    11881 ggcggcgcta agcctcgtcc aggtgcctac agggacgacc cggtgctcgg tgctcgccgg
    11941 cccggcgagc actctcttca ttcgtggacg ggccgtgctc ccagcacccc ctgaggcgcc
    12001 cacggaatcc accgaactcg acctcatggt cggaacggca ggacttctcc tcgccgcggc
    12061 acggatggcc gagcccgatc tcgcctggat tgcacgggct cgtgaccacc tcaccacctg
    12121 gacgccccaa tgtgcctgga agcggccctg gtcggacctc gcacacggaa tgatcggggt
    12181 ggaatgggct cgattccgag ccgcccacac tctcggtgaa gacaccgggc gcctcgcagc
    12241 gggactgatc gcggggctcg agcacgctgt ggaggactcg atgtacggcg cagcctggtg
    12301 ctccggcgct gccgggggcc tcgtcgtcct cgcggacctg cacgagtccg gacacgacgt
    12361 gcccgcagac ttgacccgac gcctgacccg acgagtcgcc accggcggcc ccggcgtcgt
    12421 cgatgtctcg gtctgccacg gcgtcgccgg tcggatccag gcgctgctgc gtgcagaaga
    12481 gggccggctc atcaccgacg gccgcgaacg tgcccaagag ctgtggcgcc gctcggccga
    12541 aacagcccgc acagaaggaa tccagaccgg tgctccgggc cggacggcta tcctcgagta
    12601 cttcctcggc tgggcgggcg tcgccgacac cgcccaccga ctcctccacg gggcaggcct
    12661 tttcgacgcc gtctccctga ttccaccgac gaaggagatc tgacatggcc atcaccatcg
    12721 accacgtgtc gctcgactac ggcgagttcg cactcaagga cgtcactttt gacgtgcaac
    12781 ccggagaggt cgtcggcttt ctcggcccga acggttcggg taagtccacc acattgcgag
    12841 tcctgctcgg cctcgaacgc ccagacagcg gaacggtcct gatcgccggc cagaggtaac
    12901 aggacatcgg tcgtccactg cgggtcatcg gttccctcat cgacaccaat tggatcaacg
    12961 gatcccagcg cacccaggac tatctgtcgt ggctagcggc gtccaacgac ctcgacaagg
    13021 cccgcatccc ggagctgctc gaacgcgtcg gccttgccca cgtccacaag cgcaaggtgt
    13081 cgaagctctc ccttgggatg cggcaacgcc tgggtatcgc ggcagcgttg ctcggcgacc
    13141 cggcctacct ggtgttcgac gagccgctga acgggctcga tcctgagggc atccgatggg
    13201 tgcgtaggct cctcggcgag ctccgcgacg acgggcgggc catcctgctc tctagccaca
    13261 tcctcgccga ggtcgccgag gtcgccgacc gggtcgcgat gatctccgac ggcgccatcg
    13321 tcggatacgg cagtctcccc gagttcgagg gcggcattgg cctggtcgcc gtagtttctg
    13381 atcccgaccg ggccgtcgcg gtcctcatcg agaaggggta cgaggccacg cacacaggca
    13441 cccccgaggt cctcgtctcc ggggacgctc acgggggcga cgtggcccgg gctctcgtcg
    13501 aggccgacat caccttcgaa tccatcgcca aacgcgaggg cgaccttgag aacgccttct
    13561 tctcccgcct cgtcaagaag tgaccggcat gcgcactctg cgcacagagc tgcggaaagt
    13621 cgtcgcctac cggctgccgc tgttcgtagc cgtcggcgcc ctgctgctcg tggggctgtg
    13681 ggacgtcacg atcctggctc ggggccagtc cggcctcagg gcgatggatt cctccctcgc
    13741 gttcagcggg atcgtgcttc ccacggcgtg gttcatcatc cccatgctcc tcgtcggagc
    13801 cgacacctgc gagggcacgt tgtggcccgc gctgcactcc cggcccggaa ccactcgtgt
    13861 gctgatgggc aaggcggtgg ccgccgtggt cgtcgccgtc gttacggccc tcctggccgc
    13921 gctcatgctt gccgggctga ctctcgtcac gtcccacgga gcccccaccg tggaggtgct
    13981 tcccgccgtg atcggacgtt tgctcatcca ggccatgttg tgcacagtga tcgccttctc
    14041 gatctacgtc ctcaccggtt atcagggcgc atcgtggatc atcctcggcc tcctggtgtg
    14101 gatccacttt gtcgaacggg tactctcctc ggcgctaccg ggcaacgcag gaatgctcgg
    14161 gatgccgttc cgcctcgttg acttctggat ccgcggcaag tggagcgcga ccatgcctca
    14221 actcgagatg ttcggcttcg gcccactggc cgtgtacacc gccgcgctcg ccgcgctggc
    14281 ggccggctcc ttcatcttct tctccgacag ctccgggcgc acctggggca gaaagcgctg
    14341 gtgaacccat gtccttcacc ctcgcggacg gccgcggcgc cgaccggtcg cccacggtcg
    14401 agagcacacc gtgggcgacc acgctccgct ggatgcgcac cctggtcgtc aagaacggtc
    14461 ttgcacccat ccttctgcgc agcgtcctcg ttccgatgct gctgtccttc gccggtgccc
    14521 tgttcatgat gctcgggccg gtgccgatcc ggcctgacgc tgcaggtggt atccccgacc
    14581 gcgacgtcgt gttcctcttc ctcggctaca tgctcctcgg ccaactggtg gtgatcgtat
    14641 ccggcgcgtg gctacacctc cgggatgtcc tctcccggtc tctgggcggc atctacaccg
    14701 ccgtcccgga tcgtcgggcc gtgacgctcg gcaccgccct cgtggccgcc gtcgtcggcg
    14761 cactgggtgc gctggcgagt gttctcaccg gcgtggtgac gtttatggtc gtcgcagggg
    14821 gcgatctcgc cgccacgatg agttcaccgc gagtcatgca gatgctactc ggcctcccgt
    14881 tcggcgccgc gatgctctcc gtcatcgccg tcgctgtcgc ggtgctcgtg cgtcagccca
    14941 ttgcagcggc ctgcctcctc gtcatctggg ccacctacgg tgaagacgcc gtcggtctca
    15001 tccccggtgt cggcccggtg gtgaagctgc tgcttccgat caccaacggt caggcagtcg
    15061 caggcgcccc gggtgtccag ggcatctcgg gttcttccct cgttgcggga ctgtggatgg
    15121 cggtcctcgc ggcgatctcc gtcgtcgtcg ccgtcgtcgt cgagcgccgc cgccgaggct
    15181 gggtctcctg acgactcagc ctcggttctt ggagcccgtc gccgcgcatc tccgggtgcg
    15241 cggcgacgcc acgggggcgg accgtatcgc ctatggggcc atccgatggg atgaaccgcc
    15301 agcggaaacg agtacctaag ctggccccat gttgatctgc gaagacgtca tgatccttct
    15361 cgccgaacca cgcgggatga tcgagaactg ggatgcgcgg cgacagtgga gtctcacggc
    15421 cggagccctg tgtgacctcg aagagctcgg cgccatcgca attgaaggca agcaggtgcg
    15481 ggtgctctcc gagcaggcca ccggtcacgc ggcccttgag acaatcctca cgcgcatcgt
    15541 cgaccgacgc gatcgcaagc tcccctcgat cctgcgcgat tccgcggcgt gtccgctgga
    15601 ggacatcatc gaggggctct ccgcccgagg cgtcctggaa ttgaagagca agagccgctt
    15661 cggcctgttg ccgagccgat acacggtaac cgactcgacc gtggagaaca acttgcgtgc
    15721 cgccatgacc aacactctcc acgggcgtgg caatcggcac catctcagcg tgctcgccat
    15781 catcaacagc gtcgaggtgg tccaccaggc actcaaacac gaggccgctg gcgtcaagga
    15841 ccgtgagatc tccgccttgc tcgaggatgt caaggactcc tcgacgatga tgtcggcgct
    15901 gcggtcctcc actcgtggca tcggcagcgc cctccccgcc atcgccgggg gcatgtgacc
    15961 gccgcgaccg ggccgcgact cgcgcacgca aagaaggcac cacggtcacg tccgtccccc
    16021 acggacgtga ccgtgcggag gcgccgcgca ctctcgcgga tcagtcgtcg agacctagct
    16081 cggcgatgtt ccactcgtga gcgcggatga tcgcctgaac gcggtctcgc acgccgagct
    16141 tcgcgatgag acgagcaagg tatgacttca ccgtcgcctc ggtgagacct agagcgtccg
    16201 cggtctcacg gttgctcatg ccgcgcccga gtagcttgat gacgtccatc tcccgcccgg
    16261 tgatgaaccg cgccgccatg ggcggggccg accgcttgtc ctcgcggatc gcatcgacca
    16321 cgtgagcgat caccccgggt gacaacgttt gctcgaccat gacagtgcgg cggacatcgc
    16381 cagcgccctc tctcccactt ctggccttca gcgccgtagg ggaggcagcg ttgggaagtc
    16441 tcttatcgct gctgatcctc atggcgctcg tcgcgaacac acaacccctc aaatgggtca
    16501 tcgcgctcgc ggtcgcatcc gtggcatggg gcacggtggc gtcggcctac ggtgtgttcc
    16561 gtctcgacgg cggcattgcc gcactgctgc cgatcctggc gggcgtcgtg ttacaggggg
    16621 ccgtcttgcg gtcgtcgctc ttgccacgcc gactggagcg gaacgaactc gcggctgcgg
    16681 tcacccgtgc cgaaacggcc agagcagcag agcggcggcg cctcgccggt gaacttcacg
    16741 acatcgtcgc gcacgacctc actatcctga cgatgctttc tgccaccggg cagaatctcg
    16801 acgactccgg aaggtacaaa ccacgttcgc ccgcatggta tcgacatccc ggtcggcctt
    16861 ccccaaactc tgccagctcc tcgacgtgct cgaacgaacg gaggcacctc cggtcagtgt
    16921 gagcgcctcc accacccgcc ccgacgtcgg agcggcgctg accagcggca tcgaagaact
    16981 cacgcgactc ggattctctc cgtccctcac atagttggat gtggtccccc gatccgtgca
    17041 acacgggctg cgtcgaagca tcagcggaat gctcgccaac gccgcgaaat atgcagagcc
    17101 cggcacgccc gtcgacatcg atctcgctct caccgccgat gaggtcgccc tccgagtcgt
    17161 caacacgtcg tcgtcgacgg gtcagattca cggaccagag agaatagggc ttggcctgaa
    17221 caaccttcag gagcaggcgg agtgtttcaa cgggaccttc cacgcggaac tccggcagca
    17281 tcgatgggtc tccgaactgc gcgtcccgtt gcaacctcac gcggcagaag ccgtccgcaa
    17341 cctttccacc tggcccgccg aacagatgtc atagcgaaac gagccccata gggacacccc
    17401 ccgacaccgc ctgccgcaac cagctcatca acacctgccg cgcacccgtc gaatgcgcca
    17461 acgccctgct gaaatcctcc ttcaaggccc tacgccgcat caccttatgc ccctggagaa
    17521 tcggacacat caccaccgtc gccctcatac ttttaaccac caacggcggc tgctggtgag
    17581 aaaacctctc tcggcgatgc ctttcactga gccagctatc agactagacc gcatctttct
    17641 aaatcaggga accagatggg tcattgtcct gacctatctg tctgtgatga tttcgctgtc
    17701 ccaactgatc cgctagaccg tacgtgaggg ggcgccccac tggagcatcc ccctctcgca
    17761 ccctcagaga acgccggtgg agcgcaagag gggacccagg actgttcggt cgaggccgcg
    17821 gcggatcact gtgggagccc acagaggtcg tccgtcccgg agccgggacg cagccgtgag
    17881 cagtacccgt atgtcgtaca cgctgcccca cacctcgggg acgccacggt ccacatcaaa
    17941 cagcgtatag acggcttcca tgccggtacg cactgagtat tcagtggtga acacggtgtc
    18001 gcggtcggtg tgggcaaatt gtccgaggaa ggcgaggttg acgctgcctg cggggacgac
    18061 atcgggccgg tccgcacggc tccgaggcat gaagaaggcg gtgatgaacg gcatcatgca
    18121 gggcatgcag accgctgaag tggcggccat ctcgtcaatc tgcgccggag gcaccccgat
    18181 gtggtaaagg aattcgcgag tgatttcttc gccggtgcag tctcgcatcg gttttttcac
    18241 ataatcgccg gggcgatcag tgaagagtcc gtagatccag atgactagtt tgtcagcggg
    18301 ttgagctgca aaatggggtt ggcggttgat ggtccaggac atcatccaag aggaatcacg
    18361 gacagtgaca atgccgccgg tggtcactct cccctcaaaa ggattccgtt ggcagatctt
    18421 ctccaggtac ggcgggatac gatcgtcgag ggtggtcagc gtcgctgatt cccagttagt
    18481 cagttggggg tcgctgcaga acttttcggg atggccgaag gactcatctt gacgggccat
    18541 gtttttccac aggctccaga tgccatcgtc gtggatgcgc gcgtcaaggg ctggggcttg
    18601 gtgatggtcg ccccaggtgg agttttccac gcacgatccg ttagtgacga agaccacgtc
    18661 attctcggtg aggtcgatgc cgccggggaa tccgttgcgg gtccattcga tccgacgagc
    18721 catcttgcgc agcggtgcag tggggtcgcc tggtacggcg gtcttctcaa cgaggacgtt
    18781 ggtgactcgg gtgtcgtatt ggaaggtgac gccttggtct tgcagccagg tcaccagggg
    18841 caggatgagc gactcgtact gattatattt ggtgaatttg agcgcggtga aatcggggag
    18901 accaccaatg tggtgaataa aacgttgaag atagagcttc atctccagcg cactgtgcca
    18961 ttcttcaaag gcaaacattg tgcgccagta gagccagaac gtggagtcca ggaagtcccg
    19021 cccaaggacg tcagtgatct tcagatcagc gaggtcttca tcccgggtaa aaaagagtcg
    19081 accaatatca agttgagccc gagtggtgag gtcgaatcgg ccatcggtgc gaccgtctcg
    19141 accttggtct ttggtggctc gcatgaggga gtagttgggg tcatccttat tgagccagga
    19201 gaactcgtcg aggacagatg caccgggggt ttccagtgag ggaatggatc ggaagaggtc
    19261 ccagagacac tcgaagtgct cttccatttc gcgcccccca cgaatgagga atcctttgcc
    19321 tggatccacg atgccgtcgc aggcccctcc agatagtggt gaggcttcga ggatggtgat
    19381 gcggtgcggg tctacttggg catctcggat gaggaatccg gcagcagcga gtgaggcgag
    19441 tccggcgccg acaagatggg cagatgccgt gtcagcgcga tgggatttgc ggggtcgagc
    19501 aaaggcttcg tagtttccgc tgctgtagta cacgacgtgt ccttccgtgg agcgccgagc
    19561 tggcgtcgcc gtagctgtgg tcccagcgag aatacctctt tcggagtccg ctccgcttta
    19621 gattgcggtt gtcgcagcca cggccaagcc gccccggcgg ccactcaagg ccccgatacg
    19681 ctgggagttc atcggatcca cgaggtgaac cagaatgcag acagccccca tgcccacttc
    19741 cggacctccg gagacccacc ccgccccacc gacagagggt cgccgagagc gcaacaagcg
    19801 gctcaaggcg gaggccattt tggccgcagc ggaagacctc tttcgacacc acggatacac
    19861 tgccgtcacc acccagcaga tcgccgaagc agcacaggta tccaatggca gtcttttccg
    19921 cttcgccggc actaaagcgg acctgttgat tcgggtgatg gagagccgcc ttcggctggg
    19981 ccgtgaacaa ggcttacaga tggccaggag cggagctgac cctgtcgagg cgatcatcgc
    20041 gctgctgcac ccgatcgctg aaaccgggat gccccaccct gaagtcgtcg tggcctacca
    20101 gcgagaactg ctgttcgcgg aggctccaga gcgcggcgcc gaattggatt cagtcgaagc
    20161 catggaggca gcaatccggg aggttctcac gatcgagcgc cccggatacg acgaacagac
    20221 cgtgcacttc gcagcgttca cgatctattc gacgatctat atggatctcg ttcgagtcag
    20281 tgtggggcga gcgtcagcgc aggacttgcc gcgacggctt cgggcgacga ttcggacctt
    20341 gctggacacg ctgatccccg cgaaggaggg aatggtgtca gcagcagacc cggcccgagt
    20401 gccgcagcgc agctcgacgg gttccgcgcc gggtcaacgc tccacagtgc gcacgtagcg
    20461 ttcgccgact cgattcgccc atccgtgggc ggcgaaggaa cgcaacaggt cgagagcgtt
    20521 ttgtacgacg cggagatcgg tggcgccgcc agatgcacgg gtcgcggcag ccaggatgag
    20581 ttgttgatag tcatcgctgc cgctgaccag acctccgcag aagagccagc tggccgcggc
    20641 ggggtgactg aggaagcggg cggaggcagc gagtgcggct tcgacgtcgg cgactgcggc
    20701 agtgatgatc tcggtggcca ctgggtcgtg gtcgtcggtc caggcggtgg tgacggcggg
    20761 ggcgagtccg gcgagatgtt gtttggggtg tgccgtctcg ccgagtgtgc gggcgaggtg
    20821 gagggtgtcg gcgtcgttga ggttcgcgtg ggtggtgatg gtggtggcgg ggccgcgtcc
    20881 gtctgcggcg cggaccatcg cgatgagggc tcgtttgccg aggtcgacgg cggcgccttc
    20941 gtcgctggcg agccattcga cgccaccgac acgggtgagg gagtcagtgg cgtcgcgggt
    21001 ccagaaggcg ctgccggtgc cgatgatggc ggcgacggtt tcagtgccgg gtgcgccact
    21061 gaagagcagt ggtgcgacgt cgttgacgag gtggatagtg ccgtcgtact ggtgggtgat
    21121 cgccagggat cggaattggg cggcgagcgt atcggcggag gtgtcgtcga aacctgcggt
    21181 ggcgatgtag gtggcggtga cgtgatgttc ggcgacgcgg gcgatgagtg cgctgtagac
    21241 gtcgagggct tcgtcggcgg atctgctggc ggtgttggcg ctcccgaagg tttcggtgag
    21301 ggctggggtg gtgccatgcc agatttcgag tcgggtgtgg gtgccgccgc agtcggcgac
    21361 ggcgtacgac gtcgggggtg cctcggaggg tgcgctcacg gcattgattc tctctcgtca
    21421 gagggggtgg tgtggtgcgg ctggtggggt acggcgagct cgcggggaac ccgacagtca
    21481 gattgtgcac aatttaattg cgtacactgg gatcgagccc attggtccac cctcgacacc
    21541 tcgaaggaaa acacctgatg aaaccgtacg tacgcctcct tgcccgcatc ctgctcggcg
    21601 tctttttgat gtcagctggg tacagtcaca tgaccagtgc ccggatggag ttccaggctc
    21661 aggtccccga ctggttcccg atggacaagg atctggtggt gatcctctcc gggatcgtcg
    21721 agatgaccct gggcgctgcg ttgatctccg gcttccgcaa gcagatcgtc gggttggcag
    21781 ctgctgcttt cttcatcgcg atcttcccgg gcaacatcgc ccagttcatc gagggcaaaa
    21841 atgctttcgg cctggactcc gaccgcgccc gcgccatccg actgctgttc cagccgctgc
    21901 tggtgctgtg ggcactgtgg gccactgacg ccttcccggt gatcacccag tggtggaagt
    21961 cccgcaaggc aggtgccagc cagagttgag acggcagcgc cgtcctcgac agttacttct
    22021 cccgtcgagg acggcgcgtg aacgcccgct ccacaccatg ctcagcccgg accgcaccgt
    22081 gagtcgctgg ttcgccgggc tcaccgacac cttggaggac cgtcggcgct gccgcagtca
    22141 tcggaccgga tgcccgccgc ttcagtcgct gctccagctg ctgcgccagc cacatcaaca
    22201 catagttggc gaggataaac agcagtgctg ccaccagata cgccggcacg gtgttggcat
    22261 aggccgaccc catcgtgcgc gaccaactca tcagctcagg gaacgtgatc gccactccca
    22321 gcgcggagtc tttaagcacc acgatcagct gactcaccag agctggaagc atcgcggtca
    22381 acgcctgagg cagctggacg acccgcaatg tctgccaagg agtcagcccc actgacaggc
    22441 ccgcctcggc ttggccgcga ggaagaccgt ccaccccgga gcggaccaat tcggcgataa
    22501 ccgagccgtt atacaaggtc agcgcggtca ccaccgcagc caagggcgca tattggctgt
    22561 ccaagactcc ccgggcaaag aacccgaagt aggcaaatac catcatcagc aagaccggaa
    22621 cggcgcggaa gaattcgacg acgaccccgc agaaccaacg gatggggacg atcggggaca
    22681 ttcgccccat tccgaagagc aca
//
