LOCUS       NZ_CP024972            20687 bp    DNA     circular CON 18-AUG-2024
DEFINITION  Amycolatopsis sp. TNS106 chromosome, complete genome.
ACCESSION   NZ_CP024972
VERSION     NZ_CP024972.1
KEYWORDS    RefSeq.
SOURCE      Amycolatopsis sp. TNS106
  ORGANISM  Amycolatopsis sp. TNS106
            Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
            Pseudonocardiaceae; Amycolatopsis.
REFERENCE   1  (bases 1 to 8806031)
  AUTHORS   Liu,K. and Tao,M.
  TITLE     Discovery of new natural product by Amycolatopsis speibonae genome
            mining
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 8806031)
  AUTHORS   Liu,K. and Tao,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (21-NOV-2017) School of Life Sciences and Biotechnology,
            Shanghai Jiao Tong University, 1954 Huashan Road, Shanghai, Shanghai
            200030, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP Assembly v. 3
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 116.0x
            Sequencing Technology             :: Illumina HiSeq 4000; PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_019330265.1-RS_2024_08_18
            Annotation Date                   :: 08/18/2024 03:49:46
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,321
            CDSs (total)                      :: 8,231
            Genes (coding)                    :: 8,179
            CDSs (with protein)               :: 8,179
            Genes (RNA)                       :: 90
            rRNAs                             :: 4, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 75
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 35 of 52
            Pseudo Genes (internal stop)      :: 4 of 52
            Pseudo Genes (multiple problems)  :: 6 of 52
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 21:02:24
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 6997581
            Orig. end                         :: 7018268
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP024972.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..20687
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="CDPS"
                     /region_number="29"
                     /rules="CDPS"
                     /tool="antismash"
     cand_cluster    1..20687
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="CDPS"
                     /kind="single"
                     /product="CDPS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20687
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="False"
                     /core_location="[10000:10687](+)"
                     /cutoff="5000"
                     /detection_rule="CDPS"
                     /neighbourhood="10000"
                     /product="CDPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10687
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="CDPS"
                     /neighbourhood="10000"
                     /product="CDPS"
                     /protocluster_number="1"
     gene            complement(177..1154)
                     /locus_tag="CVV72_RS32225"
                     /old_locus_tag="CVV72_32080"
     CDS             complement(177..1154)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007028550.1"
                     /locus_tag="CVV72_RS32225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CVV72_32080"
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="WP_219147642.1"
                     /transl_table=11
                     /translation="MTHAIRAEGLVKHYGETKALDGVDLEVPAGKVVGVLGPNGAGKTT
                     AVRILATLIRPDRGHASVFGYDVVKNPMAVRSMIGLTGQYASVDEDLSGTENLVLLGRL
                     LEFSRADAKKRAADLLERFELTGAAGRAIKTYSGGMRRRLDLAASLVGRPKVLYLDEPT
                     TGLDPHARNEVWAVVRTLVADGTTVLLTTQYLEEADQLADTITVFDHGHVVANGRADEL
                     KRRTGGQTLQVRPSALADLDAVERILAGLTGVRPNRDDDTGLLTAPVADPVLLSTLVRK
                     LDEAGITADELALRLPSLDEVFLALTGKKTDESTKDTTPEGSLV"
     gene            1291..2307
                     /locus_tag="CVV72_RS32230"
                     /old_locus_tag="CVV72_32085"
     CDS             1291..2307
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016337750.1"
                     /locus_tag="CVV72_RS32230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CVV72_32085"
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="WP_219147644.1"
                     /transl_table=11
                     /translation="METAAKTLLIGILDGMVIEERVVPRGAGRKLVSGLLIGAVVPFAV
                     LTALRLVGYDGNTYTIAALALTPYAGIATLILGVLALGLRRWWTGVVALVLTCTIAALV
                     LPRAFANEQKALDGKHVRVLASNMLGGQADPDRIVGYVKEHRVDVLSLTEMTPEAITGL
                     ERAGLFQVLPYHVLHPAEWASGSGLVSRYPLTPLKLSGNSDYKQPSASVDLGDGVRIEV
                     VAVHPAAPMWDRHAWVGEAKDLPYADAEHDIRILAGDFNASLDHALFRELLTRGYVDAA
                     DQLGKALAGTWTNGLVPPVPIDHVLADKRTAIADFKVLETPGSDHDAVYAEIVLPGK"
     gene            2333..3169
                     /locus_tag="CVV72_RS32235"
                     /old_locus_tag="CVV72_32090"
     CDS             2333..3169
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007028552.1"
                     /locus_tag="CVV72_RS32235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CVV72_32090"
                     /product="hypothetical protein"
                     /protein_id="WP_219147645.1"
                     /transl_table=11
                     /translation="MKKLWGVLALSLVAACVPGQLPPSEAKSALGFAARPGEARSLGLQ
                     DPVTEIQRLFRPGPGRTGVALARAGGNVIGVGFREFPGESRWEPIAWVSGDEGRSVREI
                     VLPQDRPGHWAPAAIAADGDRVLVAGALGGDVRVWASGDAGTSWTVSPVHVRGSDLWFS
                     TVLRTGGKWLLAGGSAAGALIVTGEPGAWETVSLGDGRILGGTVDKAGEPVLFGDRTEW
                     DRARTSNRSCLVVWVADGGWQRGELGCPADRLIAAATLDDGRVMLKGDRDLWIRPS"
     gene            complement(3162..3974)
                     /locus_tag="CVV72_RS32240"
                     /old_locus_tag="CVV72_32095"
     CDS             complement(3162..3974)
                     /EC_number="2.3.1.286"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016337749.1"
                     /locus_tag="CVV72_RS32240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CVV72_32095"
                     /product="Sir2 family NAD-dependent protein deacetylase"
                     /protein_id="WP_219147646.1"
                     /transl_table=11
                     /translation="MSELERAAELIDGAGALLVCAGAGMGVDSGLPDFRGDEGFWKAYP
                     PYERLGISFVELADPRHFAEDPELAWGFYGHRLALYRATVPHDGFRLLRSWGARTPGGT
                     RAFTSNVDGQFQKAGYSRVAEAHGSIHHLQCLARCTKEIWPADDIDVPIDEDTMRAPEP
                     LPSCPRCGGLARPNILMFGDYDWLGQRSQAQLDELNAWRREHRDLVVVELGAGQAVPTV
                     RRYSELASAATGALVRINPREPKVRHGRGVSLAGNGLETLRALDALLS"
     gene            complement(3967..4275)
                     /locus_tag="CVV72_RS32245"
                     /old_locus_tag="CVV72_32100"
     CDS             complement(3967..4275)
                     /EC_number="1.14.-.-"
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009084240.1"
                     /locus_tag="CVV72_RS32245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CVV72_32100"
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="WP_016337748.1"
                     /transl_table=11
                     /translation="MAVVKINAIEVPEGAGPELEKRFAARLHAVDNQPGFLGFELLRPV
                     SGESRYFVYTKWESEEAYQAWASGPAREAHAGERAKPVSTGANLLEFEVVQASKPGE"
     gene            4337..5533
                     /locus_tag="CVV72_RS32250"
                     /old_locus_tag="CVV72_32105"
     CDS             4337..5533
                     /GO_function="GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1087: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005165347.1"
                     /locus_tag="CVV72_RS32250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CVV72_32105"
                     /product="FAD-dependent monooxygenase"
                     /protein_id="WP_255632325.1"
                     /transl_table=11
                     /translation="MADTKILISGASVAGPALAFWLARYGFQVTVVERAPSLRPGGQAV
                     DLRGTAKEVARRMGLDERIRAACTDTKGETLVDRKNRTRATIRADDFDGDGVVAEIEIL
                     RGDLTEVLYEATKETTEYVFGDRITALDERADGVDVTFAVGARRTYDMVIGADGLHSGV
                     RALAFGEESRFVRHLGSYLAFFTVPNRLGLRNWAVGYDDVGRSAGIRAIRDGDEAMAYF
                     GFAAEKVDYDYRDVEAQKALVREFAAGMEWEAPWLLDRMDEAPDFYFDSCAQVIMESWS
                     RGRVGLLGDAAFCPSPLSGQGTSLAFVGAYVLAGELAAGLDTGLKRYEAVMREFVEKTQ
                     EMGRENAESIFAKSRTALRMRYVMMRVMRLKPFAALASRKMRDVVNGIDLPDYPASRI"
     gene            complement(5778..7220)
                     /locus_tag="CVV72_RS32255"
                     /old_locus_tag="CVV72_32110"
     CDS             complement(5778..7220)
                     /EC_number="3.4.11.-"
                     /GO_function="GO:0004177 - aminopeptidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008237 - metallopeptidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020641915.1"
                     /locus_tag="CVV72_RS32255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CVV72_32110"
                     /product="M1 family metallopeptidase"
                     /protein_id="WP_255632327.1"
                     /transl_table=11
                     /translation="MRSRVPAAGLVLGAVCALIIGCTADPPPATPPPPPPMNPAPGASG
                     AGDPYYPMDGNGGYDATEYQVGITYDPAKGRLDGDTTVIANATQDLDRYNLDLRGLTVQ
                     SVEVDGKPAKFAREGEFELVVTPAEPIRNGTVFRTKIVYGGDPSATPKAGGSENGWQKS
                     KDGGAFIVGEPHSASFWYPVNETPRDKAMFTLTARVPDGWTVISNGREIQKTAANGWTT
                     TSWQERTPVASYLTTVAIDKFTVDRMALPDGTPVVNAYAPGAEDRRDTGRRLPEIIGFL
                     SSKFGPYPVDAAGGIYLDEDIHFSLETQTRPTYAKWADLITVVHETAHQWFGDSVTLKS
                     WSDICLNECLASYAQWLWQESRDNENLDDRYRAALEIMRGSQDFWTPKLVGMGAGQEFH
                     GVYDKGILAIHALRRKIGEGAFTRLLKEWPAAYRNANASWADFEAFTIKLSEQNLRPFF
                     DAWFHGTTIPPDAELLPGTLRG"
     misc_feature    complement(6927..6929)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            7219..8016
                     /locus_tag="CVV72_RS32260"
                     /old_locus_tag="CVV72_32115"
     CDS             7219..8016
                     /NRPS_PKS="Domain: Abhydrolase_1 (20-117). E-value:
                     2.9e-23. Score: 74.7. Matches aSDomain:
                     nrpspksdomains_CVV72_RS32260_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1036: alpha/beta hydrolase fold protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016337745.1"
                     /locus_tag="CVV72_RS32260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CVV72_32115"
                     /product="alpha/beta fold hydrolase"
                     /protein_id="WP_219147648.1"
                     /sec_met_domain="PF00561 (E-value: 1.8e-18, bitscore: 66.0,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 4.4e-18, bitscore:
                     65.6, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEGSLVVIQRDGLITFGGDGPPIVLLHGLMGRATTWWRVARRLEP
                     YGRVHGLDARGHGRGPRGGPWRTERFADDVAAVLRTFGEPAVLIGHSMGGLHAWVTAAT
                     YPELVRAVVCEDFAPDQRGRTVDTWRGYFESWPVPFRSLAHVREFFGDTGDYFIECVEE
                     REDGYHLIASLPDLYEIAAEWGRRDFWEFVERVKCPLLAIEGERTAMPHGQQAELAARV
                     PGGLGRHIVVQGAGHVVHDEAPETYLGAVEAFLSDVLGQPFAS"
     misc_feature    7231..7233
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     aSDomain        7279..7569
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CVV72_RS32260_Abhydrolase_1.1"
                     /evalue="2.90E-23"
                     /label="CVV72_RS32260_Abhydrolase_1.1"
                     /locus_tag="CVV72_RS32260"
                     /protein_end="117"
                     /protein_start="20"
                     /score="74.7"
                     /tool="antismash"
                     /translation="PPIVLLHGLMGRATTWWRVARRLEPYGRVHGLDARGHGRGPRGGP
                     WRTERFADDVAAVLRTFGEPAVLIGHSMGGLHAWVTAATYPELVRAVVCEDF"
     CDS_motif       7471..7527
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CVV72_RS32260_0001"
                     /evalue="2.10E-04"
                     /label="NRPS-te1"
                     /locus_tag="CVV72_RS32260"
                     /protein_end="103"
                     /protein_start="84"
                     /score="13.9"
                     /tool="antismash"
                     /translation="PAVLIGHSMGGLHAWVTAA"
     gene            complement(7998..8432)
                     /locus_tag="CVV72_RS32265"
                     /old_locus_tag="CVV72_32120"
     CDS             complement(7998..8432)
                     /GO_process="GO:0061077 - chaperone-mediated protein
                     folding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016337744.1"
                     /locus_tag="CVV72_RS32265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CVV72_32120"
                     /product="co-chaperone YbbN"
                     /protein_id="WP_034310116.1"
                     /transl_table=11
                     /translation="MSKCKRFVCVLAGVLALITGFGNGVASAAPAAENVMTVTSANYAE
                     VMNISRQKLVIMDFGATWCPPCRQMKPVIERLAGEYGGRFLLGEVDVDQSRDLSTRYNI
                     RYLPTLVGVRNAAELPSSRNIGYPGEARLRAWIDAQLAKG"
     gene            complement(8445..8795)
                     /locus_tag="CVV72_RS32270"
                     /old_locus_tag="CVV72_32125"
     CDS             complement(8445..8795)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007028559.1"
                     /locus_tag="CVV72_RS32270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CVV72_32125"
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="WP_219147650.1"
                     /transl_table=11
                     /translation="MLPLITRTELLSRMESGSVVVVDTMPVAYFSKEHLPEARNIPGFP
                     YERAAEFTDRLAPEVLPDKAAEIVVYCANTPCRNSEFVGRRLLELGYTNVRKYREGIED
                     WVANGLPTWSSS"
     gene            complement(8888..9841)
                     /locus_tag="CVV72_RS32275"
                     /old_locus_tag="CVV72_32130"
     CDS             complement(8888..9841)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016337742.1"
                     /locus_tag="CVV72_RS32275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CVV72_32130"
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_219147651.1"
                     /transl_table=11
                     /translation="MEIQVRHLRVICEIAASGSLNRAAAGLGLGQPALSHQLRRIERMV
                     GGPLFHRDQHGVRPTELGALILRRARAIVLTFDELEHDFHRQEPETGESIRIGWNDSAI
                     TGSLLGGLRDLRPGEPFRTRADTSRTRLLAQVANRGIDLALIMICGGRGLPVPPEVRTM
                     TLVEEPSFVAIPAEHPLAAEEEIELAELAGEDWIVSSGGDGCRVVFREMCLAHGFDPRI
                     THDADIDTTREDLVSGGYGVGLIQPTRPSADGLAIRPLVGAPMSVRHVLAWREDGRCAP
                     GVPELAASARAGYWRLAGRTAPYRAWLHRHGRLTAG"
     misc_feature    complement(9905..9922)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 14.95"
                     /tool="antismash"
     misc_feature    complement(9929..9942)
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: strong, score:
                     17.65"
                     /tool="antismash"
     gene            10001..10687
                     /locus_tag="CVV72_RS32280"
                     /old_locus_tag="CVV72_32135"
     CDS             10001..10687
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) CDPS:
                     CDPS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007028561.1"
                     /locus_tag="CVV72_RS32280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CVV72_32135"
                     /product="tRNA-dependent cyclodipeptide synthase"
                     /protein_id="WP_034310123.1"
                     /sec_met_domain="CDPS (E-value: 3.6e-75, bitscore: 251.3,
                     seeds: 17, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPRPLPLTEHCADPLARAEHVCLGVSPFNSHFTVDRIADLARWAM
                     SAFRGFHFFVPDGPSAFTLEALGYDPVRAAQKAQRQGNYTRNKIVRALGQICVPDPHAL
                     ILDAAALEADSAYLGLLSEAHHRFATDPEFAEQCLGATGWVLDRRLPEGEHPTRDQLRS
                     AVRYFLAELPMFVGTVAVAGVGSSVFAYHQRVAFLERLYRGELSWRPLPGQGFVVLEQA
                     VPERVE"
     gene            10690..12003
                     /locus_tag="CVV72_RS32285"
                     /old_locus_tag="CVV72_32140"
     CDS             10690..12003
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005165331.1"
                     /locus_tag="CVV72_RS32285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CVV72_32140"
                     /product="cytosine permease"
                     /protein_id="WP_219147652.1"
                     /transl_table=11
                     /translation="MEHDDFSLRRVPADRRYSWISVALQRFGQVSSFHQFLLGAVLGFG
                     MTFWEAVLAITIGSVLLEIITILMGVAGTREGLSTSVLARWTGFGTGGSSLVGLLMTLS
                     LAGWFGVQNDVFAHGLHALMGGPPVWVWALAGGALVTAIVVFGFHAMAWTAYLTVPAFL
                     ALAGFSIVSALGDHSLPALMAEPPPGPSMSLAQGTTLVAGAFIMGAIMTPDMTRFNRTA
                     SDVVKQTLVSVTLGQYLIGLIGVLLAHAAKSADVVGIITSSSGVLGTLILVTAILKIND
                     WNLYSSSLGLVNTVQVLLSRRLDRTTATLLLGGLGTVLSAIGILDHFTTFLTWVGVLTP
                     PVAGVVIAEYYVVRRWKPELDATRASGELPSTCPSWVPSALICWVAGAAVGAWLPWGIP
                     TVNSVLGAFLLYILLGRRTAAAVSSTAMTSSGGSKTRS"
     gene            12000..12974
                     /locus_tag="CVV72_RS32290"
                     /old_locus_tag="CVV72_32145"
     CDS             12000..12974
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007028563.1"
                     /locus_tag="CVV72_RS32290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CVV72_32145"
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_219147653.1"
                     /transl_table=11
                     /translation="MTKEFDVVQLDVHHLRVIRAIADTGSLSRAAIALGVTQPAVSAQL
                     KRLENMLGYRLFDRCEGGVTPTPMGELLLRRTAALLPQLDKLLEDIEQRVCPSGPPDVV
                     RVVAVASALVARLPSLVTGLWPEVSEVQVVHDDHPERLLPLLAQRRAELGLVKDYPGYE
                     LEIPANVDTAVVVTEPTFVLLPEFHPLAREKVVDLRDLRDEAWVTVSDSSAATFTKYFA
                     DTCARHGFSPSFTHQVTSQQVALLVVKAGAIGLSQPICDPGNHGIVPRPLRGDVLPRRH
                     ILAWNRETFVAGRREELLSAVVEAYWAEARTAPVYAEYLDGNA"
     misc_feature    12219..12221
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(13059..14501)
                     /locus_tag="CVV72_RS32295"
                     /old_locus_tag="CVV72_32150"
     CDS             complement(13059..14501)
                     /EC_number="3.4.11.-"
                     /GO_function="GO:0004177 - aminopeptidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008237 - metallopeptidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016337738.1"
                     /locus_tag="CVV72_RS32295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CVV72_32150"
                     /product="M1 family metallopeptidase"
                     /protein_id="WP_219147654.1"
                     /transl_table=11
                     /translation="MTVRLRWQEPLCTALLATTMIGACPASAAAEPAPGSDGYVHVSPD
                     GTVLGPDPYYPEDGNGGYDVGKYSLALQYAPYSMLLSGRATITATATQDLSRFDLDLRG
                     LTVRSVTVDGVAATFRRAGEHELVITPRTPVAEGRPFTVVVEYDGRPEPIPTARGRVGW
                     LAAYGDSAVATGQPRSAMTWFPVNNTEADKAALHVSVTVLNEFSVLGNGSQVSDVPAGP
                     GRHTVTWSEETALAPSTAMLGIGRWEVERITLPGGRTAVNAYHPCAVDKRQIGGRLPEV
                     LEFLTGKFGDYPQSAAGGLFLDRSLGYTHGAQTRPVYGRTATIADLVYAVAYQWWGAGV
                     SGKMWRDALMPESVARYAVWLWDEAKNGADLDRRYRERVAEVRDDPAFWAPKLTDPGKG
                     AEFAPTAKAVLMVHALRRHIGDDAFFQIMAGFPMINPQGNQNWHDFELYVSAMTQRELG
                     EFNQAWLDGTVRPPDELLFPGM"
     gene            14669..15823
                     /locus_tag="CVV72_RS32300"
                     /old_locus_tag="CVV72_32155"
     CDS             14669..15823
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1184: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016337737.1"
                     /locus_tag="CVV72_RS32300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CVV72_32155"
                     /product="MFS transporter"
                     /protein_id="WP_219147655.1"
                     /transl_table=11
                     /translation="MLPLPALLALTTTVFLGCLTEVLPAGLLLGMSEDLGVSPSATGQL
                     VTVYAITTALTAVPLTGATLRVPRKRLLLALITGFLVTNLVIAVSSSYPVILAARVVSG
                     ALTGVMWSLVAGYAMRLAPPGLTGRALAVAMSGTPVGFALGVPAGTALGELADWRWAFA
                     VMALITVPLLVWVLVAVPAVPADPAGPTRPLAASRLPGMRPVLATVALFSFGHNVAYTY
                     VGPVLAGLDAESLLGAVLLVFGCAAVGGMAAVGSALDSHPRAVLLSCTAVTAAAVVLLG
                     ISDGVHGLVLMAAGLWGLGFGGAPTAFQAVTALLAGPTADAAQSLTIAAWNGAVAGGAL
                     IGGLLLPLGTGLLPWCAALVILSPLLFSRRVVLSAPGDRCRTRR"
     gene            complement(15768..16730)
                     /locus_tag="CVV72_RS32305"
                     /old_locus_tag="CVV72_32160"
     CDS             complement(15768..16730)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007028566.1"
                     /locus_tag="CVV72_RS32305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CVV72_32160"
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="WP_219147656.1"
                     /transl_table=11
                     /translation="MADFDRRTALKGGLTASAVGLLGTATISAADAASGVTEPKIHGTA
                     AWSARPPNGAIEVQNHKPTYIVVHHTVEPGNVTDYTLEHAFWASRSIQNFHMDTRGWID
                     TGQQFTNSRGGHITEGRHRSLEILRGGTQHVLGANVGNNNSTCIGIENEGLYSTEDVTP
                     ALWDSLVKLVAYMASQYGISPEFIKGHRDFNSTECPGTVLYNRLPELRTEVGKLLGTSS
                     PKADLPEWPLLKPGDSGPRVRMAQELLRARGFAVPTDGLFGQSTKDAVAAVAARHGLER
                     DTCGATAATDETGFLGSDVWPLIVGSGTDLRALKARLAG"
     misc_feature    16715..16729
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.37"
                     /tool="antismash"
     gene            complement(16819..17694)
                     /locus_tag="CVV72_RS32310"
                     /old_locus_tag="CVV72_32165"
     CDS             complement(16819..17694)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005165321.1"
                     /locus_tag="CVV72_RS32310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CVV72_32165"
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="WP_219147657.1"
                     /transl_table=11
                     /translation="MGVDADVLTEWFDEVGRDLPWREPECTAWGVLVSEIMLQQTPVAR
                     VQPIWLEWMARWPVPSALAASSQGEVVRAWGKLGYPRRALRLHAAAAVIAAEHGDVVPS
                     DVDTLLALPGIGAYTARAVAAFAYGKRAPVVDTNVRRVVARAVHGAGDAGPPSNTRDMA
                     DVEALLPAEDAPAAKLSAALMELGALVCTARSPRCADCPIYDDCAWQHAGRPAYAGPAK
                     QLQKFAGTDRQVRGLLLDVLRGSEGPVEKARLDLVWHESGQRDRCLDSLLVDGLLEQTR
                     DGLFALPGEH"
     misc_feature    complement(17658..17673)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.64"
                     /tool="antismash"
     gene            complement(17713..18204)
                     /locus_tag="CVV72_RS32315"
                     /old_locus_tag="CVV72_32170"
     CDS             complement(17713..18204)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020641910.1"
                     /locus_tag="CVV72_RS32315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CVV72_32170"
                     /product="carbonic anhydrase"
                     /protein_id="WP_219147658.1"
                     /transl_table=11
                     /translation="MTSIDVLLKRNQELGDVTPGDRSSPRPSLQVAILTCMDARIRVFE
                     IFGLIQGESHILRNAGGVVTDDMIRSLALSQRKLGTREVLIVQHTDCGLSMVTEDDFKD
                     ELEAASGLRPTWSVEAFREVEDSVRRSVQRVRRSDFLPHTDSVRGFVYDVKLGRLTEVA
                     "
     gene            complement(18256..19356)
                     /locus_tag="CVV72_RS32320"
                     /old_locus_tag="CVV72_32175"
     CDS             complement(18256..19356)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1078: LacI family
                     transcription regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005441636.1"
                     /locus_tag="CVV72_RS32320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CVV72_32175"
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="WP_005165317.1"
                     /transl_table=11
                     /translation="MGRPIRTRRQATLASLAAELGVSRTTVSNAYNRPDQLSPELRRRV
                     LETARRLGYPGPDPVARSLRTRKAGAVGLLLTENLSYAFRDPAAVGVLEGLALACEDAG
                     VGLHLVPASPGREDVAAVHRAGVDGFVVYSVPDDDPHLGAVLERPVPTVIVDQPRVDGV
                     DRVGPDDAAAVTAMAEHLISLGHRQIGVLCMRLARERNDDFVSIQRQSAAHFHVQRIRL
                     EALAAAFSAAGVDWATVPVVERFDHTVDDGASAARQLLDAYPQVTAVICTSDILALGAL
                     AEAERRGLRVPQDLTVTGFDGITEAERSGLTTVHQPVLEKGKAAGKLLLSSADRVGPKV
                     ITLQTELRVGRTSAPPRTAEERWFGP"
     misc_feature    19328..19345
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 19.59"
                     /tool="antismash"
     misc_feature    complement(19492..19506)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 19.11"
                     /tool="antismash"
     misc_feature    19493..19504
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 16.21"
                     /tool="antismash"
     misc_feature    complement(19493..19508)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 18.05"
                     /tool="antismash"
     misc_feature    complement(19552..19566)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.96"
                     /tool="antismash"
     gene            19557..20489
                     /locus_tag="CVV72_RS32325"
                     /old_locus_tag="CVV72_32180"
     CDS             19557..20489
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1252: cation ABC
                     transporter, periplasmic"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007028570.1"
                     /locus_tag="CVV72_RS32325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CVV72_32180"
                     /product="metal ABC transporter solute-binding protein,
                     Zn/Mn family"
                     /protein_id="WP_219147659.1"
                     /transl_table=11
                     /translation="MNSRRTKSVFAAVSALAVLALGATACASGDKASTGSGSQNASAAN
                     PGGGEKIKVVASTDVWGSVVTAVGGDKVEVTSIIHDPSADPHSYETTASDAIAAKNAKL
                     TLSNGGGYDDFFSKLADQATGAQKLVAVDIAATGNENEHVWYSLPGVEKIADQVAAKLG
                     EIQPASKDAFTANAAAFKGKTQELLKKVSGLGGSGAKVVATEPVAHYLLDSAKVTDATP
                     PAFAEAVEAEQDVPAAALNEVKQLISGKQVKALVNNAQTTTPVTQQVVGDAKNAGIAVV
                     DVTETLPQGVTDYIAWMTKEVDALAGALK"
     misc_feature    20558..20573
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.63"
                     /tool="antismash"
     misc_feature    20653..20667
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.25"
                     /tool="antismash"
ORIGIN
        1 gccgccgaac agatagacga acatgaccag gaagatgatc ggcgcgatgg tgacgtcggc
       61 cagctgttcc gggttcttgc ggatcttcag gacaccgcgc caggcaaggg aaagcccgtg
      121 ccgcacgctg ctcgacgggg aaacgcgccg tggtggcgcg ggcatcgcga tggtcgtcat
      181 accaggctcc cttccggagt ggtgtccttt gtggactcgt cggtcttctt gccggtcagc
      241 gcgaggaaca cctcgtcgag gctgggcagc cgcagcgcca gctcgtccgc ggtgatcccg
      301 gcctcgtcca gcttgcggac caaagtggac agcaggaccg ggtcggcgac gggcgcggtg
      361 agcagcccgg tgtcgtcgtc ccggttcggc cggacgccgg tgagcccggc caggatgcgc
      421 tcgacggcgt cgaggtcggc gagcgcggac ggccggacct gcagcgtctg gccgccggtc
      481 cgccgcttga gctcgtcggc gcgcccgttc gccacgacgt gcccgtggtc gaacacggtg
      541 atcgtgtcgg ccagctggtc ggcctcctcc aggtactggg tggtgagcag caccgtcgtg
      601 ccgtcggcga ccagcgtccg gaccacggcc cagacctcgt tgcgggcgtg cgggtcgagc
      661 ccggtggtcg gctcgtccag gtacagcacc ttgggacgcc cgaccaggct cgcggcgagg
      721 tcgagccgcc gccgcatccc gcccgagtag gtcttgatcg cgcggccggc ggcgccggtc
      781 agctcgaacc gctccagcag gtcggccgcg cgcttcttcg cgtccgctcg cgagaactcc
      841 aggagcctgc cgagcaggac gaggttctcc gtaccggaaa ggtcctcgtc gaccgacgcg
      901 tactgcccgg tcagcccgat catgctccgg accgccatcg ggttcttcac gacgtcgtac
      961 ccgaagacgc tcgcgtggcc gcggtccggc cggatcaagg tggccaggat ccggacggcg
     1021 gtcgtcttcc ccgcgccgtt cggccccagc accccgacca ccttgcccgc cgggacctcc
     1081 agatcgaccc cgtcgagcgc cttcgtctcc ccatagtgtt tgaccaggcc ctcggccctg
     1141 atcgcgtgag tcatcgtttc ctcctgtgga tctcgccccg ccgaccaagg tgcacccggt
     1201 gcctggcaga ccgcgcacag tgcgctggca gcggctgaca ggacctgata agcgctggta
     1261 gacgcggtgt gaggaggttg tgaaggtgtt gtggagacgg ccgccaagac gctcttgatc
     1321 ggcatactcg acggcatggt gatcgaagaa cgcgtggtgc cccgaggcgc cgggcgaaag
     1381 ctggtcagcg ggctgctcat cggggcggtc gtgccgttcg cggtgctgac ggcgttgcgg
     1441 ctggtgggct acgacggcaa cacgtacacg atcgcggcgc tcgcgctcac gccgtacgcc
     1501 gggatcgcga cgctgatcct cggcgtcctc gcgctgggac tccgccgctg gtggaccgga
     1561 gtggtcgcgc tggtgctgac ctgcacgatc gcggccctgg tccttccccg cgcgttcgcg
     1621 aacgaacaga aggcgctcga cgggaaacac gtgcgcgtgc tggcgtcgaa catgctcggc
     1681 gggcaggcgg acccggaccg gatcgtcggc tacgtgaagg agcaccgggt cgacgtcctg
     1741 agcctgaccg agatgacgcc cgaggcgatc accgggctcg aacgggccgg gctgttccag
     1801 gtcctgccct accacgtgct gcacccggcc gagtgggcgt cgggctccgg gctggtgtcg
     1861 aggtatcccc tcacaccgct gaagctgagc ggcaattcgg actacaagca gcccagcgcg
     1921 agcgtggacc tcggggacgg cgtccggatc gaggtcgtcg cggtccatcc ggcggcgccg
     1981 atgtgggatc ggcacgcgtg ggtcggcgag gccaaggacc tgccgtacgc cgacgccgag
     2041 cacgacatcc ggatcctggc gggcgacttc aacgcgagcc tcgaccacgc gctcttccgc
     2101 gagctgctga ccaggggata cgtggacgcg gccgatcagc tggggaaggc gttggcgggg
     2161 acctggacga acgggctggt gccgccggtg ccgatcgacc acgtgctggc ggacaaacgg
     2221 acggccatcg cggacttcaa ggtgctggag acgccgggca gcgatcacga cgccgtctac
     2281 gcggaaatcg tcctgcccgg aaagtgacct tccgctggca ggcttcccgc tcatgaagaa
     2341 gctctgggga gtgctcgcgc tttccctggt cgcggcgtgc gtcccggggc agttgccacc
     2401 gtccgaggcg aagagcgcgc tgggtttcgc cgcccggccc ggtgaggcac ggtccctcgg
     2461 cctccaggac ccggtcaccg agatccagcg gctgttccgg ccggggcccg gccggaccgg
     2521 agtggcgctg gcccgcgcgg gcgggaacgt gatcggcgtc ggcttccggg agttccccgg
     2581 ggaaagccgg tgggaaccga tcgcctgggt gtccggggac gaaggccgca gtgtgcggga
     2641 gatcgtgctg ccgcaggaca ggccggggca ttgggcgccg gcggcgatcg cggccgacgg
     2701 cgatcgggtt ctcgtggccg gagccctcgg cggcgacgta cgggtatggg cctccggcga
     2761 cgcgggcact tcctggacgg tgtcgccggt gcacgtgcgg ggaagcgacc tctggttttc
     2821 cacggtgctc cggacaggcg ggaaatggct gctggccggg ggttccgcgg ccggggcgct
     2881 gatcgtgacc ggcgagcccg gcgcctggga gaccgtttcc ctcggggacg gccggatcct
     2941 cggcggaacc gtcgacaagg cgggtgagcc ggtgttgttc ggcgaccgca ccgagtggga
     3001 ccgggcccgg acctcgaacc ggtcgtgcct ggtggtgtgg gtcgccgacg gcggctggca
     3061 gcggggtgag ctgggctgcc cggcggatcg gctcatcgcc gcggcgaccc tcgacgacgg
     3121 gcgggtgatg ctgaaaggcg accgcgacct gtggatccgc cctagctgag cagcgcgtcc
     3181 agcgccctga gcgtttccag gccgttgcct gccagtgaaa cgccgcggcc gtgccggacc
     3241 tttggctcgc gcgggttgat ccggaccagc gcgccggtcg cggcgctggc cagctccgag
     3301 taccgccgca ccgtcggcac ggcctgtccg gcgccgagtt ccaccaccac gaggtcgcga
     3361 tgctcgcgac gccacgcgtt cagctcgtcg agctgggctt ggctgcgctg accgagccag
     3421 tcgtagtcgc cgaacatcag gatgttgggc cgggcgaggc cgccacagcg tggacaggac
     3481 ggcaacggct ccggcgcgcg catcgtgtcc tcgtcgatcg ggacgtcgat gtcgtccgcg
     3541 ggccagatct ccttggtgca cctggcgagg cactgcaggt ggtggatgga cccgtgcgcc
     3601 tcggcgaccc gggagtagcc cgccttctgg aactgtccgt ccacattgga cgtgaacgcg
     3661 cgcgtgccgc ccggtgtgcg cgctccccag gaccgcagga gacggaaccc gtcgtgcggg
     3721 acggtggcgc ggtacagcgc gagccggtgc ccgtagaaac cccaggccag ctcggggtct
     3781 tcggcgaaat gccgcgggtc ggccagttcg acgaagctga tgcccagccg ctcgtacggc
     3841 ggatacgcct tccagaaacc ttcgtcgccc cggaaatcgg gcaggccgga gtcgacaccc
     3901 atcccggcac cggcgcagac gagcagcgcg ccggcgccgt cgatcagttc cgcggctcgt
     3961 tcgagctcac tcacccggct tcgaagcctg gacgacctcg aattccagca gattcgcgcc
     4021 ggtggagacc ggcttcgcgc gctcgcccgc gtgcgcctca cgcgccgggc cggacgccca
     4081 cgcctggtac gcctcttcgg actcccactt ggtgtagacg aagtagcgcg actcgccgga
     4141 gaccgggcgg agcagctcga agccgagaaa gccgggctga ttgtcgacgg cgtgcagccg
     4201 cgcggcgaac cgcttctcca gctcggggcc tgcgccttcg gggacctcga tcgcgttgat
     4261 cttcacgaca gccatgccgc cagcctacga cgaaactctt ttgcgccgcg atgtgatgcg
     4321 tgggaccttc cagaggatgg ctgacaccaa gatcctcatc tccggggcga gcgtcgccgg
     4381 gcccgcactg gccttctggc tagcccggta cggcttccag gtgaccgtcg tggagcgcgc
     4441 gccttcgctg cgccccggcg gccaggccgt cgacctgcgc ggaacggcca aggaggtcgc
     4501 gcgccggatg ggcctggacg aacgcatccg cgccgcctgc acggacacga agggcgagac
     4561 gctcgtcgac cggaagaacc gcacgagggc cacgatccgc gccgacgact tcgacggtga
     4621 cggcgtcgtc gccgagatcg agatcctgcg cggcgacctg accgaagtgc tctacgaggc
     4681 gaccaaggag acgacggagt acgtcttcgg cgaccggatc accgcgctgg acgagcgggc
     4741 cgacggcgtc gacgtcacct tcgccgtcgg tgcccggcgg acctacgaca tggtcatcgg
     4801 ggcggacggg ctgcattcgg gagtgcgggc gctggccttc ggcgaagagt ccaggttcgt
     4861 ccggcatctg ggctcctacc tggcgttctt caccgtgccg aaccggctgg gcctgcggaa
     4921 ctgggccgtc ggttacgacg acgtcggccg gtccgccggg atccgcgcca tccgcgacgg
     4981 cgacgaggcg atggcctact tcgggttcgc cgcggagaag gtggactacg actatcgcga
     5041 cgtcgaggcg cagaaggcgc tggtgcgcga gttcgcggcc gggatggagt gggaggcgcc
     5101 ctggctgctg gaccggatgg acgaggcccc cgacttctac ttcgattcgt gcgcccaggt
     5161 gatcatggag tcctggtcgc gtggccgcgt cgggctgctg ggcgacgccg ctttctgccc
     5221 ctcgccgctt tccgggcagg gcacgagcct ggcgttcgtc ggcgcgtacg tcctcgccgg
     5281 ggaactcgcc gccggtctcg acaccgggct caagcgctac gaggcggtca tgcgcgagtt
     5341 cgtcgagaag acgcaggaga tggggcggga gaacgcggag tcgattttcg cgaaatcgcg
     5401 taccgcgctg cgcatgcgct acgtgatgat gcgggtcatg cggctcaagc cgttcgccgc
     5461 gctggcgtcg cggaagatgc gggacgtggt gaacggcatc gacctgccgg actaccccgc
     5521 ctctcgcatt taggtgacta aacgcggggc cgggcacacg atcgccccgc gggccgtgtc
     5581 gcgaaagcca ctttcgagac gctggatgtc ccgaaagtgg ctttcgcgac atccagtgtc
     5641 ccgcccccag cgtgcgaacc gggaagggtt gcgaaagcca ctttcgcaac cttgagcgtt
     5701 gcgaaagtgg ctttcgcaac gctctcgcgt cgggagcgac cgcgccggac gcatttaggt
     5761 gactaaatgc gtgggggtca gcctcgcagg gtccccggca gcagctcggc gtccggcggg
     5821 atcgtcgtgc cgtggaacca cgcgtcgaag aacggccgca ggttctgctc cgaaagcttg
     5881 atcgtgaacg cctcgaagtc cgcccaggag gcgttggcgt tgcggtacgc cgccggccat
     5941 tccttcagca ggcgcgtgaa cgctccttcg ccgatcttcc gccgcagcgc gtggatggcc
     6001 aggatcccct tgtcgtagac gccatggaac tcctgcccgg cccccatgcc gaccagtttc
     6061 ggggtccaga aatcctggct gccgcgcatg atctcgaggg cggcgcggta gcggtcgtcc
     6121 aggttctcgt tgtcccgcga ctcctgccac agccattgcg cgtacgacgc gaggcattcg
     6181 ttgaggcaga tgtcggacca cgatttcagc gtcaccgaat cgccgaacca ctggtgcgcg
     6241 gtttcgtgca ccacggtgat caggtcggcc catttcgcgt aggtcggcct ggtctgggtc
     6301 tccagcgaga aatggatgtc ctcgtcgaga tagatgccgc ccgccgcgtc caccggatac
     6361 ggcccgaact tcgagctcag gaaaccgatg atctccggca gccgcctgcc ggtgtcgcgc
     6421 cggtcctcgg cgcccggcgc gtacgcgttg accaccgggg tcccgtccgg gagcgccatc
     6481 cggtcgacgg tgaacttgtc gatcgccacc gtggtcagat aggaggccac gggcgtgcgc
     6541 tcctgccagg acgtcgtggt ccagccgttg gccgcggtct tctggatctc acgcccgttc
     6601 gagatgacgg tccagccgtc cggcacccgt gcggtgaggg tgaacatcgc cttgtcgcgc
     6661 ggggtctcgt tgaccggata ccagaacgac gccgaatgcg gctcgccgac gatgaacgcg
     6721 ccgccgtcct tcgacttctg ccagccgttc tcgctgccgc ccgccttggg cgtcgccgac
     6781 gggtcgccgc cgtagacgat cttcgtgcgg aagacggtcc cgttccggat cggctcggcg
     6841 ggcgtcacca ccagttcgaa ttcgccctcg cgcgcgaact tcgccggttt cccgtccact
     6901 tcgacggatt gcacggtcaa gccgcgtaag tccaggttgt accgatcgag gtcctgggtc
     6961 gcgttcgcga tcaccgtggt gtcgccgtcg agccgccctt tcgcggggtc gtacgtgatc
     7021 cccacttggt attcggtcgc gtcgtaaccg ccgttcccgt ccatcgggta gtacgggtcg
     7081 cccgcgccgg aagcgccggg agccgggttc atcggcggcg gcggtggggg cgtggccggc
     7141 ggcggatcgg cggtgcagcc gataatcagg gcgcagacgg cccccagtac cagaccggcg
     7201 gcggggacac ggctgcgcat ggaggggagc ttagtggtga tccagcgcga cgggttgatc
     7261 actttcggcg gtgacgggcc gccgatcgtc cttctgcacg ggttgatggg cagggcgacg
     7321 acgtggtggc gggtcgcgcg aaggctcgag ccgtacgggc gtgtccacgg tctcgacgcg
     7381 cgaggtcacg ggcgcggtcc gcgcggcggg ccatggcgca ccgagcggtt cgccgacgac
     7441 gtcgccgcgg tgctgcggac cttcggcgaa cccgccgtcc tgatcggaca ttcgatgggt
     7501 ggcctgcacg cctgggtcac cgcggccacg tatcccgagc tcgtccgcgc cgtggtctgc
     7561 gaggatttcg cgccggacca gcgcggccgg accgtggaca cctggcgcgg gtatttcgaa
     7621 tcgtggccgg tcccgttccg ctcattggcc cacgttcgcg agttcttcgg cgacaccggc
     7681 gactacttca tcgaatgcgt cgaggagcgc gaagacggct accacctgat cgcgtccctc
     7741 ccggacctgt acgagatcgc ggccgaatgg ggcaggcgcg acttctggga attcgtcgaa
     7801 cgcgtgaaat gcccgctgct cgcgatcgaa ggcgaacgga ccgcgatgcc ccacggccag
     7861 caggccgagc tggccgcacg cgtgcccggc ggcctcggac ggcacatcgt cgtccaaggc
     7921 gccgggcacg tggtgcacga cgaagcgccg gagacctacc tcggtgcggt cgaagcgttc
     7981 ctctccgacg tcctcggtca gcccttcgcg agctgagcgt cgatccaggc gcgcagccgc
     8041 gcctcgcccg ggtagccgat gttccgcgag gacggcagct cggcggcgtt gcggactccg
     8101 accagcgtcg ggaggtagcg gatgttgtac cgggtggaca ggtcccggct ctggtcgacg
     8161 tcgacctcac cgagcaggaa ccggccgccg tattcaccgg cgagccgttc gatcaccggc
     8221 ttcatctggc ggcacggcgg gcaccaggtc gcgccgaagt ccatgatgac cagtttctgc
     8281 cgcgagatgt tcatgacctc ggcgtagttg gccgacgtca ccgtcatcac gttttccgcc
     8341 gccggcgcgg ccgaagccac gccattgccg aaaccggtga tgagcgccag cacgccggcc
     8401 agcacgcaga cgaaccgttt gcacttggac aagacgatct cctttcagga cgaagaccag
     8461 gtcggcaagc cgttcgcgac ccagtcttcg atgccttcgc ggtatttgcg gacgttcgtg
     8521 tacccgagct ccagcagccg ccgcccgacg aattcactgt tgcggcacgg cgtgttcgcg
     8581 caatagacga cgatctcggc ggccttgtcc ggcagcactt ccggtgccag ccgatcggtg
     8641 aattcggccg cccgttcgta cgggaaaccc ggaatgttgc gtgcctccgg aagatgttcc
     8701 ttcgagaaat aggcgaccgg catcgtgtcc accacgacca ccgatccgga ctccatccgg
     8761 gagagcagtt ccgtacgggt gatcaacggc agcatggtgc cccttctttc ggcgaccgtg
     8821 attgacgatt cccatcgtcg gggcgctcgc gggacacgct ctagtgccgc atcggcatgc
     8881 cgaagggtta tccggcggtc agcctgccgt ggcggtgcaa ccaggctcgg tacggcgccg
     8941 tccgcccggc gagccgccaa tatccggccc tcgccgaagc ggcgagttcc gggacaccgg
     9001 gcgcgcaccg gccgtcctcc cgccaggcca gcacatgccg cacgctcatc ggcgcgccca
     9061 cgagcggccg gatggccagc ccgtccgccg acggccgggt cggctggatc agcccgacgc
     9121 cgtatccgcc gctgaccagg tcctcccgtg tggtgtcgat gtcggcgtcg tgggtgatcc
     9181 gggggtcgaa accgtgcgcc aggcacattt cgcggaagac cacccggcag ccgtcgccgc
     9241 cgctcgacac gatccagtcc tcgcctgcca gctcggcgag ttcgatctcc tcttcggcgg
     9301 cgagcgggtg ctccgcgggg atcgccacga acgacggctc ctccaccagc gtcatggtcc
     9361 gcacttccgg cggcaccgga aggccgcgtc cgccgcagat catgatcagc gcgaggtcga
     9421 tgccgcggtt cgcgacctgc gcgagcagcc gcgtgcggga ggtgtccgcg cgcgtgcgga
     9481 acggctcgcc cgggcgcagg tcgcgcagtc cgccgagcag cgaacccgtg atggcgctgt
     9541 cgttccagcc gatcctgatc gattcgcccg tctcgggttc ctgccggtgg aagtcgtgct
     9601 ccagttcgtc gaaggtgagc acgatcgccc gcgcccgccg caggatcagg gcgccgagtt
     9661 cggtgggccg caccccgtgc tggtcgcggt ggaacagcgg gccgccgacc atgcgctcga
     9721 tccggcgcag ctggtggctg agcgcgggct gcccgagccc cagcccggcc gcggcccggt
     9781 tgaggctgcc ggaggcggct atctcacaga tcacgcgaag atgccgaacc tgaatctcca
     9841 tgacttcgta taccgcgacc cgttcgcgcc cggcaccccc gaaagtcgag acacccgatt
     9901 tctcataacc cggtgacaac attcggtggc aatacccgtg ccagccggcc gtggctacgt
     9961 tcggtcgacg ccccgcatat cacgcgaatc aggagccgtc ttgccgcgac cattgccgct
    10021 cacggagcat tgcgctgatc cgctggcgcg agccgaacac gtttgcctgg gtgtcagccc
    10081 gttcaacagc catttcacgg tggaccgtat cgccgatctc gcccgctggg ccatgtcggc
    10141 ctttcgcggt ttccatttct tcgtccccga cggcccgtcc gccttcaccc tcgaagcgct
    10201 cggctacgac ccggtgcgcg ccgcgcaaaa ggcacagcga cagggcaatt acacccggaa
    10261 caagatcgtc cgcgcgctgg ggcagatctg cgtgccggat ccgcacgcct tgatcctgga
    10321 cgcagcggcg ctcgaagccg acagcgcgta cctcggcctg ctttccgagg cacaccaccg
    10381 attcgccacc gacccggagt tcgccgagca gtgcctcggc gccacgggct gggtgctgga
    10441 ccggcggctg cccgagggcg aacatcccac gcgcgaccag ttgcgcagcg cggtccggta
    10501 cttcctcgcc gagttgccga tgttcgtcgg caccgtcgcc gtggccgggg tcggcagctc
    10561 cgtgttcgcc tatcaccagc gggtcgcctt cctcgaacgg ctctaccgcg gcgaactctc
    10621 gtggcggccg ctgcccggcc aaggtttcgt cgtcctcgaa caagccgtcc cggaacgagt
    10681 ggagtgaccg tggaacacga cgacttctcc ctccgccggg tacccgccga ccgccgctac
    10741 tcctggattt ccgtcgcgtt gcagcgattc gggcaggtgt cctcgttcca ccagttcctg
    10801 ctcggcgcgg tgctcggctt cggcatgacc ttctgggaag cggtactggc catcacgatc
    10861 ggttcggtgc tgctggagat catcaccatc ctgatgggcg tcgcgggcac ccgggagggg
    10921 ctttcgacgt cggtactcgc gcgctggacc ggattcggca ccggcgggtc ctcgctcgtc
    10981 ggtctcctga tgacactgag cctggccggc tggttcggcg tgcagaacga cgttttcgcc
    11041 cacggtctcc atgccttgat gggcggcccg ccggtgtggg tgtgggcgct cgcgggcggc
    11101 gcgctggtca ccgcgatcgt cgtgttcggc tttcacgcga tggcctggac ggcctatctg
    11161 acggtgcccg ctttcctcgc gctggcgggg ttttcgatcg tctcggccct cggtgatcat
    11221 tcgctgcccg cgctgatggc cgagccaccg ccgggaccgt cgatgtcgct ggcacagggc
    11281 accacgctgg tggcgggggc gttcatcatg ggcgcgatca tgacgccgga catgacccgg
    11341 ttcaaccgga ccgcgtccga cgtggtgaag cagaccctgg tcagcgtcac cctcggccag
    11401 tacctcatcg gcctgatcgg ggtcctgctc gcgcacgcgg cgaaaagcgc cgacgtggtc
    11461 gggatcatca cctcgtcgtc cggtgtgctc ggcacgctga tcctggtcac cgcgatcctg
    11521 aagatcaacg actggaacct ctattcgtcc tcgctcgggc tggtgaacac cgtgcaggtg
    11581 ctgctgtccc ggcggctgga ccgcaccacc gcgaccctgc tgctcggcgg tctcggcacg
    11641 gtgctctccg cgatcggcat cctcgaccac ttcaccacct tcctgacgtg ggtcggcgtg
    11701 ctcacgccac cggtggccgg ggtggtgatc gccgagtact acgtggtccg tcgctggaaa
    11761 ccggagctgg acgccacccg cgcgtccgga gagctgccgt ccacctgccc gtcctgggtt
    11821 ccgtccgcgc tgatctgctg ggtggccggg gcggcggtgg gggcctggct gccgtgggga
    11881 atccccaccg tgaactccgt tttgggtgct ttcctcctgt atattctgct cggcagacgg
    11941 accgcggccg cggtgtcctc cacggccatg acttcttccg gcgggtcgaa aacccgttcg
    12001 tgaccaagga gttcgacgtc gtacagctgg atgtccacca cctgcgggtg atcagggcga
    12061 tcgcggacac gggaagcctt tcccgggccg cgatcgcgct cggtgtcacc cagcccgcgg
    12121 tttccgcgca gctcaaacgg ctggagaaca tgctgggcta ccggttgttc gaccggtgcg
    12181 agggcggcgt gaccccgacg ccgatgggcg aactgttgtt acgccgcacc gccgctttgc
    12241 tgccacagct ggacaaactg ctcgaagaca tcgagcagcg cgtctgcccc agcggtccgc
    12301 ccgacgtggt ccgggtggtg gcggtggcca gcgcgctggt ggcgcgtctg ccctcgctgg
    12361 tgaccggatt gtggcccgag gtctccgagg tgcaggtcgt gcacgacgac caccccgaac
    12421 gactgctgcc gctgctggcg caacggcgcg cggaattggg gctggtcaag gattatccgg
    12481 gatacgagct cgaaatcccc gcgaacgtgg acaccgcggt ggtggtgacg gagccgacct
    12541 tcgtcctgct gccggagttc catccgctgg cgcgcgagaa ggtcgtcgac ctgcgtgacc
    12601 tgcgggacga agcgtgggtg acggtgtccg attcgtcggc ggccacgttc accaagtact
    12661 tcgccgacac ctgcgcgcgg cacggcttca gcccgtcgtt cacccatcag gtgacttcgc
    12721 agcaggtggc gctgctggtg gtcaaggcgg gcgcgatcgg gctgtcacaa ccgatctgcg
    12781 atccggggaa ccacggcatc gtgccccggc cgctgcgcgg ggacgtgttg ccgcgcaggc
    12841 acattctcgc gtggaacagg gagaccttcg tagcgggacg gcgggaggaa ctgctctccg
    12901 ccgtggtcga agcgtactgg gccgaagcga ggaccgcgcc cgtctacgcc gagtacctgg
    12961 acggaaacgc gtgacctgct gggcgaacgg accggcagag ccacgaagac tcgtgagtgg
    13021 taaggacggt tagaaccgtc cttaccactc acgaggcctt acatcccggg aaacaggagt
    13081 tcgtccggcg gccgcaccgt gccgtccagc caggcctggt tgaactcgcc gagctcgcgc
    13141 tgcgtcatcg cggagacgta gagctcgaag tcgtgccagt tctggtttcc ctgcggattg
    13201 atcatcggga agcccgccat gatctggaag aacgcgtcgt cgccgatgtg acggcgcagc
    13261 gcgtgcacca tcagcaccgc cttggccgtc ggcgcgaatt cggcaccctt gccgggatcg
    13321 gtgagcttgg gcgcccagaa ggccgggtcg tcgcgcacct cggccaccct ctcccggtag
    13381 cggcgatcca ggtcggcacc gttcttggcc tcgtcccaca gccagacggc gtaccgcgcg
    13441 acggattcgg gcatcagtgc gtcgcgccac atcttgccgc tcaccccggc tccccaccat
    13501 tggtacgcga cggcgtacac cagatcggcg atggtggccg tgcggccgta caccggccgg
    13561 gtctgcgcgc cgtgcgtgta gccgagggag cggtcgagga acagcccgcc cgccgccgat
    13621 tgcgggtagt cgccgaactt cccggtgagg aattccagga cctcgggcag ccgcccgccg
    13681 atctgccgtt tgtccacggc gcaggggtgg taggcgttga ccgccgtccg gccaccggga
    13741 agagtgatcc gctcgacctc ccagcgcccg atgccgagca tcgccgtgct cggcgcgagg
    13801 gcggtctcct ccgaccaggt gacggtgtgc cgtcccgggc ccgcgggtac gtcggagacc
    13861 tgggaaccgt tgcccagtac ggagaattcg ttcaggacgg tgacggagac gtgcagggcc
    13921 gccttgtcgg cttcggtgtt gttgacgggg aaccaggtca tcgccgaacg cggctgcccg
    13981 gtggccacgg cggaatcgcc gtaagcggcg agccagccga cccggccacg cgcggtgggg
    14041 atcggttccg gccggccgtc gtactcgacc accacggtga acggcctgcc ttcggccacc
    14101 ggggtccgcg gggtgatcac cagctcgtgc tcgcccgccc gccggaacgt ggcggccacg
    14161 ccgtcgacgg tgaccgatcg gacggtgagc ccgcgcagat cgaggtcgaa ccggctgagg
    14221 tcctgagtag ccgtcgcggt gatcgtcgcc ctgccgctca gcagcatcga gtacggcgcg
    14281 tactgcagcg cgagtgagta ctttccgacg tcgtaaccgc cgttgccgtc ctccgggtag
    14341 taaggatcgg ggccgaggac ggtcccgtcg ggcgagacgt gcacgtatcc gtcgctgccg
    14401 ggtgccggct cggccgccgc ggaagccggg caggcgccga tcatcgtggt ggcgagcaac
    14461 gcggtgcaca gtggctcctg ccaccgaagc cgcactgtca tgaacgagcc ttctctctca
    14521 gggggaggat gtccggtcat cgtgcgtacg tgcccgccgc gcgcggcact gccagccggt
    14581 catgccgccg ggttatcccg gccgataacc cctcggcata cccgccaggg actatcgcgt
    14641 gccgcgagag ggaggagatc gtcgaggcat gctgcccctc ccggcgctgc tcgcgctgac
    14701 gacgacggtc ttcctcggct gcctcaccga agtgctgccc gccgggttgc tgctgggcat
    14761 gtccgaggat ctgggtgttt ccccgtcggc caccgggcag ctggtgacgg tctacgcgat
    14821 caccaccgcg ctcaccgccg ttccgctcac cggcgcgacc ctccgggtac cgcgcaaacg
    14881 cctgctactg gcgctgatca caggcttcct ggtcaccaac ctggtgatcg ccgtgtcctc
    14941 gtcgtacccg gtgatcctcg cggcgcgggt cgtgtccggg gcgctgaccg gggtgatgtg
    15001 gtccctcgtg gccggttacg cgatgcgtct cgccccgccg ggactcaccg gacgggcgct
    15061 ggccgtggcc atgtccggca cgccggtcgg cttcgccctg ggtgtgcccg ccggtaccgc
    15121 gctcggcgaa ctcgccgact ggcgctgggc gttcgccgtg atggcgctga tcaccgtgcc
    15181 gctgctggtc tgggtgctcg tcgcggtgcc cgctgtgccc gccgatccgg caggtcccac
    15241 ccgcccgctg gccgcgtcac ggctgccggg aatgcgtccc gtgctcgcga cggtggcgct
    15301 gttctcgttc gggcacaacg tggcctacac ctacgtcgga ccggtgctcg ccggtctgga
    15361 cgcggaatcg ttgctgggcg cggtgttgct ggtgttcggc tgtgccgcgg tgggcgggat
    15421 ggccgcggtc ggctccgccc tcgacagcca tccgcgcgcg gtactgctgt cctgcaccgc
    15481 cgtcaccgcc gccgccgtcg tcctgctggg gatcagcgac ggtgtccacg gtctggtgct
    15541 gatggccgcc ggactgtggg gcctggggtt cggcggcgcg ccgaccgctt tccaggccgt
    15601 caccgccttg ctcgcgggcc ccacggccga cgccgcccag tcgctcacga tcgcggcctg
    15661 gaacggcgcc gtcgccggtg gcgcgctcat cggcggcctg ctgctgccgc tgggaacagg
    15721 gctgctccct tggtgtgccg ccttggtgat cttgtcgccg ctgctgttca gccggcgagt
    15781 cgtgctttca gcgcccggag atcggtgccg gacccgacga tgagcggcca gacgtcggag
    15841 ccgaggaaac cggtctcgtc ggtcgccgcg gtcgcgccgc aggtgtcgcg ctccagcccg
    15901 tgccgtgccg ccacggcggc gaccgcgtcc tttgtggact gtccgaacag gccgtcggtc
    15961 ggcacggcga aaccgcgtgc ccgcaggagt tcctgtgcca tccgcactcg cggcccgctg
    16021 tcgccgggtt tgagcagcgg ccactccggc agatcagcct tcggcgacga ggtccccagc
    16081 agcttgccga cctcggtgcg cagctccgga agccggttgt acagcacggt gcccgggcat
    16141 tcggtggagt tgaagtcgcg gtggcccttg atgaattccg gcgagatccc gtactgcgaa
    16201 gccatgtacg cgaccagctt caccagcgag tcccagagcg cgggcgtgac gtcctctgtg
    16261 ctgtagaggc cttcgttctc gatcccgatg caggtgctgt tgttgttgcc cacgttcgcg
    16321 cccagcacgt gctgggtccc gccacgcagg atttccaggc tgcgatgccg tccttcggtg
    16381 atgtgcccgc cgcggctgtt cgtgaactgc tggccggtgt cgatccagcc acgggtgtcc
    16441 atatggaagt tctggatgga gcgcgacgcc cagaaggcgt gttcgagtgt gtagtcggtg
    16501 acgttccccg gctcgaccgt gtggtgcacg acgatgtacg tcggtttgtg gttctgcacc
    16561 tcgatcgcgc cgttcggcgg ccgcgcgctc cacgcggccg tgccgtggat cttcggttct
    16621 gtcaccccgg acgccgcgtc ggcggcggaa atcgttgctg tccccagtag cccgacggcg
    16681 cttgccgtca ggccgccctt gagcgcggta cgtcggtcga agtcggccac gggcgaaact
    16741 cccatcatgc gcgttggccg gaaaactaac ccgccatcgc gccgatgaca accattgacc
    16801 aacttttgtc gtaatgcgtt agtgttcgcc agggagggcg aacaggccgt ccctggtctg
    16861 ttcgagcaac ccgtccacca gcaaggagtc gaggcagcgg tcgcgctgtc cggattcgtg
    16921 ccagacgaga tcgagccgcg ccttctcgac cgggccttcg ctgccgcgca ggacgtcgag
    16981 cagcaatccg cgcacctggc ggtcggtgcc ggcgaacttc tggagctgct tcgcgggacc
    17041 ggcgtacgcg ggccttcccg cgtgctgcca cgcgcagtcg tcgtagatcg ggcagtccgc
    17101 gcagcgcggc gaacgcgcgg tgcagacgag cgcgccgagt tccatcagcg cggccgaaag
    17161 tttcgcggcg ggcgcgtctt ccgccggcag cagggcctcg acgtcggcca tgtcgcgggt
    17221 gttcgagggc ggcccggcat cacccgcgcc gtgcaccgcc ctggccacca cgcgccggac
    17281 gttcgtgtcc accaccggtg cccgcttgcc gtaggcgaag gcggcgacgg cgcgcgcggt
    17341 gtacgcgccg atacccggca acgcgagcag agtgtccaca tcggacggaa cgacgtcgcc
    17401 gtgttcggcg gcgatgacgg ccgccgcggc gtgcagccgc aacgcgcgcc gcgggtagcc
    17461 gagtttgccc caggcgcgca cgacctcgcc ctgcgacgac gccgccagag ccgacggtac
    17521 cggccagcgc gccatccatt cgagccagat cggctgtacg cgcgcgaccg gtgtctgctg
    17581 caacatgatc tcgctgacga gcacacccca ggcggtgcat tccggctcac gccaagggag
    17641 gtcgcgcccc acctcgtcga accactcggt cagcacatcc gcgtcgacgc ccaccgggcc
    17701 agcttaaaac ccttacgcga cctcggtcag gcggcccagc ttcacgtcgt agacgaagcc
    17761 gcgcacgctg tcggtgtgcg ggaggaagtc gctgcgccgg acgcgctgca ccgaccggcg
    17821 cacgctgtct tccacctccc ggaacgcctc gaccgaccac gtcgggcgaa gtccgctggc
    17881 ggcttcgagt tcgtccttga agtcgtcttc tgtgaccatg gagaggccgc agtcggtgtg
    17941 ctgcacgatc agcacctcgc gggtgcccag ttttcgctgg ctgagcgcga gcgagcggat
    18001 catgtcgtcg gtgacgaccc cgcccgcgtt ccgcaggatg tgggattcgc cctggatcag
    18061 gccgaagatc tcgaacaccc ggatacgggc gtccatgcag gtcagaatcg ccacctggag
    18121 tgatggcctc ggcgacgagc ggtcaccagg agtgacatca cccagctcct ggttgcgctt
    18181 gagcagtacg tcgattgagg tcacgcgttc attggaaccg acacgccggg ggagagcaac
    18241 gtgtgcgggc acagatcacg gcccgaacca gcgttcttcc gccgttcgtg gcggcgccga
    18301 cgtgcggccg acccggagtt ccgtctgcag ggtgatcacc ttcggcccca cccggtcggc
    18361 cgagctgagc agcagcttgc ccgccgcctt gcccttttcg agcaccggct ggtggaccgt
    18421 ggtgagcccg gagcgctcgg cctcggtgat gccgtcgaag ccggtgaccg tcagatcctg
    18481 cgggacgcgc aggccccggc gctccgcttc ggccagcgcg ccgagggcga ggatgtccga
    18541 ggtgcagatc acggcggtga cctgcggata cgcgtcgagc agctggcgtg cggccgacgc
    18601 gccgtcgtcc acggtgtggt cgaagcgctc gactaccggc accgtcgccc agtcgacccc
    18661 ggccgccgag aacgcggcgg ccagcgcctc cagccggatc cgctggacgt ggaaatgcgc
    18721 ggcgctctgc cgctggatgg agacgaagtc gtcgttgcgc tcgcgggcca gccgcatgca
    18781 cagcacgccg atctgccggt ggccaaggga gatgaggtgt tcggccatgg cggtgaccgc
    18841 ggccgcgtcg tccgggccga cgcggtcgac gccgtcgacg cgcggctggt cgacgatcac
    18901 cgtcggcacc gggcgttcca gcacggcgcc gagatgcggg tcgtcgtcgg gcaccgagta
    18961 gacgacgaag ccgtcgacac cggcgcggtg cacggccgcg acgtcctccc ggcccgggct
    19021 cgccgggacc aggtgcaggc cgacgcccgc gtcctcgcag gccagcgcca gcccttcgag
    19081 cacgccgacg gcggcggggt cgcggaaggc gtaggagagg ttctcggtga gcagaagacc
    19141 gacagcgccg gccttgcgcg tccgcagtga acgggccacc gggtccgggc ccgggtagcc
    19201 gaggcggcgt gcggtctcga ggacgcgacg gcgcagctca ggggacaact ggtccggtcg
    19261 gttgtaggcg ttcgagacgg tggtcctcga cacaccgagc tctgcggcca acgacgccag
    19321 tgtcgcctgc ctcctggtgc ggataggacg gcccatccgc aaaccgtaac ggttcagaac
    19381 gttttgcaga agcatcaccc gacgtgtggc aggtctcgat tcagagtgac cctgggtaca
    19441 gctcggacct ggaccggagg cggcgtcatc cggatggggt acagttgaat ctgacaacgg
    19501 tttccattac ccggcattgg ggacacctgg ccagggcatc cgcaggagtg cagtaaatga
    19561 attcccgccg taccaagagt gttttcgcgg ccgtgtcggc cctggccgtc ctcgcgctcg
    19621 gcgcgacggc ttgcgcgtcg ggcgacaagg cgtcgacggg ttccggttcg cagaacgcgt
    19681 ccgccgcgaa cccgggcggc ggcgagaaga tcaaggtcgt cgcctcgacc gacgtctggg
    19741 gcagcgtcgt gaccgccgtg ggcggcgaca aggtcgaggt cacctcgatc atccacgacc
    19801 cctccgccga cccgcactcc tacgagacca ccgcgagcga cgcgatcgcc gcgaagaacg
    19861 cgaagctgac gctgtccaac ggcggcggct acgacgactt cttctccaag ctcgccgacc
    19921 aggccaccgg cgcgcagaaa ctggtcgccg tcgacatcgc cgcgaccggc aacgagaacg
    19981 agcacgtctg gtacagcctg cccggcgtcg agaagatcgc cgaccaggtc gccgcgaagc
    20041 tcggtgagat ccagcccgcc tcgaaggacg ccttcaccgc caacgcggcc gcgttcaagg
    20101 gcaagaccca ggagctcctg aagaaggtct cgggcctggg cggctcgggc gcgaaggtcg
    20161 tcgcgaccga gcccgtcgcg cactacctgc tcgacagcgc gaaggtcacc gacgcgacgc
    20221 cgccggcctt cgccgaggct gtggaagcgg agcaggacgt gcccgccgcc gcgctcaacg
    20281 aggtcaagca gctgatctcc ggcaagcagg tcaaggcgct ggtcaacaac gcgcagacca
    20341 ccaccccggt cacccagcag gtcgtcggcg acgccaagaa cgccggcatc gcggtcgtcg
    20401 acgtcaccga aacgctgccc cagggtgtga ccgactacat tgcatggatg accaaggaag
    20461 tggacgcgct ggcgggagca ctgaagtagt gacctccgta cctgccggag ctcgccccgc
    20521 ggtccgtgtc cgcggggcga gcctcgcgtt cggcaccagg accctctggt ccgggctcga
    20581 cctcgacgtc gagcccggcg agttcctcgc gatcctcggg ccgaacggct ccgggaagag
    20641 cagcctgctc aaggtgctgc tcggccagca ggggctgccc gagggca
//
