LOCUS       NZ_CP024972            49609 bp    DNA     circular CON 18-AUG-2024
DEFINITION  Amycolatopsis sp. TNS106 chromosome, complete genome.
ACCESSION   NZ_CP024972
VERSION     NZ_CP024972.1
KEYWORDS    RefSeq.
SOURCE      Amycolatopsis sp. TNS106
  ORGANISM  Amycolatopsis sp. TNS106
            Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
            Pseudonocardiaceae; Amycolatopsis.
REFERENCE   1  (bases 1 to 8806031)
  AUTHORS   Liu,K. and Tao,M.
  TITLE     Discovery of new natural product by Amycolatopsis speibonae genome
            mining
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 8806031)
  AUTHORS   Liu,K. and Tao,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (21-NOV-2017) School of Life Sciences and Biotechnology,
            Shanghai Jiao Tong University, 1954 Huashan Road, Shanghai, Shanghai
            200030, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP Assembly v. 3
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 116.0x
            Sequencing Technology             :: Illumina HiSeq 4000; PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_019330265.1-RS_2024_08_18
            Annotation Date                   :: 08/18/2024 03:49:46
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,321
            CDSs (total)                      :: 8,231
            Genes (coding)                    :: 8,179
            CDSs (with protein)               :: 8,179
            Genes (RNA)                       :: 90
            rRNAs                             :: 4, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 75
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 35 of 52
            Pseudo Genes (internal stop)      :: 4 of 52
            Pseudo Genes (multiple problems)  :: 6 of 52
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 21:02:24
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 4420496
            Orig. end                         :: 4470105
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP024972.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..49609
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /candidate_cluster_numbers="3"
                     /contig_edge="False"
                     /product="T1PKS"
                     /product="azole-containing-RiPP"
                     /region_number="24"
                     /rules="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or
                     hyb_KS or itr_KS or tra_KS))"
                     /rules="((YcaO or TIGR03604) and (((thio_amide and (PF06968
                     or PF04055 or PF07366)) or Lant_dehydr_C or Lant_dehydr_N
                     or (PF06968 or PF04055 or PF07366)) or (goadsporin_like or
                     PF00881 or TIGR03605)) or TIGR03882 or TIGR03603 or
                     thiostrepton or TIGR03602)"
                     /tool="antismash"
     cand_cluster    1..49609
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds(PKS_AT and (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS))"
                     /detection_rules="((YcaO or TIGR03604) and (((thio_amide
                     and (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /kind="neighbouring"
                     /product="T1PKS"
                     /product="azole-containing-RiPP"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     cand_cluster    1..45829
                     /SMILES=""
                     /candidate_cluster_number="2"
                     /contig_edge="False"
                     /detection_rules="cds(PKS_AT and (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS))"
                     /kind="single"
                     /product="T1PKS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..45829
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="False"
                     /core_location="[20000:25829](-)"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(20001..25829)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
     gene            complement(238..1173)
                     /gene="pip"
                     /locus_tag="CVV72_RS19860"
                     /old_locus_tag="CVV72_19775"
     CDS             complement(238..1173)
                     /EC_number="3.4.11.5"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0004177 - aminopeptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0030163 - protein catabolic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: Abhydrolase_1 (37-294). E-value:
                     2.9e-30. Score: 97.6. Matches aSDomain:
                     nrpspksdomains_CVV72_RS19860_Abhydrolase_1.1"
                     /codon_start=1
                     /gene="pip"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S28"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1036: alpha/beta hydrolase fold protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020421995.1"
                     /locus_tag="CVV72_RS19860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CVV72_19775"
                     /product="prolyl aminopeptidase"
                     /protein_id="WP_219145250.1"
                     /sec_met_domain="Abhydrolase_6 (E-value: 3.6e-09, bitscore:
                     36.5, seeds: 455, tool: rule-based-clusters)"
                     /sec_met_domain="PF00561 (E-value: 1.1e-27, bitscore: 96.2,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Peptidase_S28 (E-value: 8.4e-05, bitscore:
                     20.4, seeds: 12, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIDLYPPAEPYDSGLLDVGDGNTVYWETCGNPAGKPAVMLHGGPG
                     QGCTPGMRRMFDPARYRAVLFDQRGCGRSTPHASDPATDLRHNTTDHLVADMERLRKHL
                     GIERWLVTGGSWGTTLALAYAERFPERVTEVVVSSISTTRPSEIDWLYRGVGRFFPEAW
                     ARFRGDLTGDLVAAYARLMEDPDARVRTEAARSWCVWEDTVLLLETGVTVHNGPIGEWE
                     LAFARIVTHYYSHAGWLEPGELIRDAGVLRNIPGVLIHGRRDLSCPVDTAWELARAWPG
                     AELLIDDDSGHRSSDVKLAWKLAALERFAV"
     aSDomain        complement(292..1062)
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CVV72_RS19860_Abhydrolase_1.1"
                     /evalue="2.90E-30"
                     /label="CVV72_RS19860_Abhydrolase_1.1"
                     /locus_tag="CVV72_RS19860"
                     /protein_end="294"
                     /protein_start="37"
                     /score="97.6"
                     /tool="antismash"
                     /translation="VMLHGGPGQGCTPGMRRMFDPARYRAVLFDQRGCGRSTPHASDPA
                     TDLRHNTTDHLVADMERLRKHLGIERWLVTGGSWGTTLALAYAERFPERVTEVVVSSIS
                     TTRPSEIDWLYRGVGRFFPEAWARFRGDLTGDLVAAYARLMEDPDARVRTEAARSWCVW
                     EDTVLLLETGVTVHNGPIGEWELAFARIVTHYYSHAGWLEPGELIRDAGVLRNIPGVLI
                     HGRRDLSCPVDTAWELARAWPGAELLIDDDSGHRS"
     misc_feature    complement(556..558)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            1307..2386
                     /locus_tag="CVV72_RS19865"
                     /old_locus_tag="CVV72_19780"
     CDS             1307..2386
                     /EC_number="6.3.2.2"
                     /GO_function="GO:0004357 - glutamate-cysteine ligase
                     activity [Evidence IEA]"
                     /GO_process="GO:0042398 - cellular modified amino acid
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1165: carboxylate-amine ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016332251.1"
                     /locus_tag="CVV72_RS19865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CVV72_19780"
                     /product="glutamate--cysteine ligase"
                     /protein_id="WP_219145251.1"
                     /transl_table=11
                     /translation="MFTLGVEEEFVLLDPMDGSVALRAPELIECLAPGPDVTGELMRFQ
                     IETATGVCRGLDEVRSELTRLRQIVATAARADGCLMVATGIPPCGLREDALTPEPRYRR
                     MAQAFPDLIREAGTCACHVHVGLPSRDLGARVLAGLRPWLAPLLALSANSPVENGADSG
                     WSSRRFPLWDRWPTARPPEEWSGAAAYDRSLAEAVRHRAALDAAGVYFYARLSPRYPTV
                     EVRIADVCLSVDDAVLLAALVRGLVATCAGTTRPPRARGTRIGAALTAAARRGLDGPGI
                     DVFTGREADQRDLLGELVEFVRPALRAAGDEEDVERGLDALFGHGTGATRQRRLLAEAA
                     SPGEFAAGLAHATMTVPAR"
     gene            complement(2399..3004)
                     /locus_tag="CVV72_RS19870"
                     /old_locus_tag="CVV72_19785"
     CDS             complement(2399..3004)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005154150.1"
                     /locus_tag="CVV72_RS19870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CVV72_19785"
                     /product="DNA-binding response regulator"
                     /protein_id="WP_125676779.1"
                     /transl_table=11
                     /translation="MIKVLVAEDMHIVRGALVALLGLEPDIEVVAECASGDEILPLAQS
                     ARPDVALIDIDLPGKDGLTAAAELHERLPGVRTLILTSLGSPGTLRRALAAKVNGFLRK
                     DAPADRLANAVRGVAAGRRVVDGDLALAAWDSEDCPLTTREIEVLRLASVGSDPTEIAA
                     ELFLSAGTVRNYLTTIVSKLSARNRVDAVRIARESGWL"
     gene            3471..4169
                     /locus_tag="CVV72_RS19875"
                     /old_locus_tag="CVV72_19790"
     CDS             3471..4169
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1287: AraC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007034666.1"
                     /locus_tag="CVV72_RS19875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CVV72_19790"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_219154028.1"
                     /transl_table=11
                     /translation="MHEKLGEELTIDDIARAATFSKFHFSRVFQQATGVSPGRFLSALR
                     LDEAKRLLLTTSISVADISHRVGYNGVGTFSTRFSNRVGLSPSAYRRQGGFQHRLAGEP
                     LPGAKPAMVRGFVSAPPEISPGLVFVGLFPTRIPEGAPVRHTVIDVPGPYQLTDVPEGT
                     WHLVAHCVTGPLTRRGTGLTGHHGPITVEPGVTARLADLRVRPKRLFDPPVLLALPDLR
                     HRPEPVRRAA"
     gene            complement(4249..5253)
                     /locus_tag="CVV72_RS19880"
                     /old_locus_tag="CVV72_19795"
     CDS             complement(4249..5253)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007034665.1"
                     /locus_tag="CVV72_RS19880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CVV72_19795"
                     /product="DUF1702 family protein"
                     /protein_id="WP_219145252.1"
                     /transl_table=11
                     /translation="MSSLLGALRKVLFAPSLASVGFEGRGFGVPPTPATARLESIPQSV
                     VCGFEWGIDAPALWEAERRLDMVEPELRGFAYEGAAMAFTILDVMPGGRKDRTAELMSG
                     PGLPHVFLTYIGIGFAMARLPRPLWKKVLPELDGVPFHPTMSWLAVDGYAFDRAYFDTD
                     KWVGEQFVPKPYPWAGAPAYFPRACDQGIGRALWFINGGDPVKVAEAVNRFPAGRRPDL
                     WSGVGLASTFAGGCDQAGLERLREAAGSTGEYQDELGLGVVFAVKARTFSSFVPRHTHL
                     AARTLAGLSIEEAVDLADSTEVTEDAADGTPAYELWRQNIREGLAPSVGRLAA"
     misc_feature    complement(5652..5665)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 19.16"
                     /tool="antismash"
     gene            5726..6298
                     /locus_tag="CVV72_RS19885"
                     /old_locus_tag="CVV72_19800"
     CDS             5726..6298
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020629588.1"
                     /locus_tag="CVV72_RS19885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CVV72_19800"
                     /product="DNA-binding response regulator"
                     /protein_id="WP_255632785.1"
                     /transl_table=11
                     /translation="MVRGALVALLNLERDIEVVAEVGSGDKILPMAAEYLPDVAIIDID
                     LPAKDGLTAASELCQQLPSVRTLILTSLGRPGTVRRALDAKVNGFLLKDAPADKLANAV
                     RSVATGRRVIDSELALSAWEIEDCPLTPREVEILRLAANGRTVADIAAELFLSPGTVRN
                     YLATVVTKLNARNRVDAIRIAADSDWL"
     misc_feature    complement(6371..6380)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 15.26"
                     /tool="antismash"
     gene            6464..7276
                     /locus_tag="CVV72_RS19890"
                     /old_locus_tag="CVV72_19805"
     CDS             6464..7276
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1041:
                     transcriptional regulator, SARP family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016332245.1"
                     /locus_tag="CVV72_RS19890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CVV72_19805"
                     /product="AfsR/SARP family transcriptional regulator"
                     /protein_id="WP_219145254.1"
                     /transl_table=11
                     /translation="MHAMTIEPGDTAASAGAPHGVRARLLGPLELHIDDADRAPSTPKL
                     LQLLAMLLIRPGRTVHVDSLVHELWNEAPPRSVRRTLHTYVHHLRRHLDPGGTGDLLVT
                     SPPGYRLEIDAGAVDVWEFQRLHRLGRELLEEGDNAAAAHAFRTALDLWSGPPLANIHC
                     GPTLAAYTVYLLEHRRDARDRWIDAEIRAGRHREMLGVLRSLTTADPFDETLHAHLIRA
                     LGLSGRRSDALASYEWLRSRLEDELGVKPSAELRELHRELLSEGHPVR"
     gene            7321..8007
                     /locus_tag="CVV72_RS19895"
                     /old_locus_tag="CVV72_19810"
     CDS             7321..8007
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1167:
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020629590.1"
                     /locus_tag="CVV72_RS19895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CVV72_19810"
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="WP_219145255.1"
                     /transl_table=11
                     /translation="MTARTYGQFCGLARALEIIGERWSLLVIRDLVLGPKRFDELQQGL
                     PKIPMSILSTRLNELERHGVVQRRVLSQLDAGVVYELTEYGNDLDQIVLQLGLWGARSL
                     GDPTADDLFTLDSAVLSLYTTFQPDAARGVHCAFEMHYGGEMVIHAVVEDGALTAGEGP
                     HPDPDLVIEPRGPVMLKLLNGEMDAASALTSGAVAVKGDPDKLELFTRMFHIPSAPAKT
                     EGLVTH"
     gene            complement(8050..8670)
                     /locus_tag="CVV72_RS19900"
                     /old_locus_tag="CVV72_19815"
     CDS             complement(8050..8670)
                     /EC_number="2.7.7.87"
                     /GO_function="GO:0003725 - double-stranded RNA binding
                     [Evidence IEA]"
                     /GO_function="GO:0061710 - L-threonylcarbamoyladenylate
                     synthase [Evidence IEA]"
                     /GO_process="GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005154159.1"
                     /locus_tag="CVV72_RS19900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CVV72_19815"
                     /product="L-threonylcarbamoyladenylate synthase"
                     /protein_id="WP_219145256.1"
                     /transl_table=11
                     /translation="MARYFDVHPENPQRRAIGQVVDILREDGLIAYPTDSCFALGCQLG
                     NRQGIDRIRSIRKLDDRHHFTLVCQDFAQLGQFVHVDNAVFRAVKASTPGSYTFILPAT
                     KEVPRRLLHAKKKTVGVRIPDHVVTQALLGELGEPLLSSTLLLPDQEEPMTQGWDIKER
                     LEHVVDAVIDSGECGVEPTTVIDFSSGEPEIVRRGAGDTARFE"
     misc_feature    8908..8923
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 22.14"
                     /tool="antismash"
     misc_feature    8918..8931
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 18.22"
                     /tool="antismash"
     gene            9031..11352
                     /locus_tag="CVV72_RS19905"
                     /old_locus_tag="CVV72_19820"
     CDS             9031..11352
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020629592.1"
                     /locus_tag="CVV72_RS19905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CVV72_19820"
                     /product="sensor histidine kinase"
                     /protein_id="WP_219154029.1"
                     /transl_table=11
                     /translation="MPDQLAVTAEPLGTAGIDRRPRRALFLAGLIITVVFVNSCLVGLL
                     GVLLRPGVDFWHGLLAVLYVGPVLAIQLLYFSRPAVRLDTRRAKAMLVVQACLAYLPAL
                     HFDAALTSLTTLAAGSALLLLRPRTGWTVFAVLMAATTWILWTYDATWHGAVLDSITAI
                     LYALVVYLLTWLARLVTELHQARTELARRAVAEQRLAFARDLHDLLGLSLSAIALKGEL
                     VLRLLRKSLEGARAELAEITGIAQRTLSDVRSVARGYRELSLEKESRTAVSLLSASNVA
                     VRADLEPVELPVKLRTLLAKVLREGITNVLRYTGVEHCEISVREHEGRVVLEIVHDGTA
                     HEDLPEETAESLREVTEEVAGHGGELSAGPDAAGRWRLHAELPVPDQIEPAETVLAEAP
                     GHWSRIDARNVQWTLTVIFILFGLSAMTRAFMLTDDGWSIALIAGYLTASITLQLSYFA
                     RPNVRLRSRQSYALLFVQGCLIFLPLIPLGSAWVSMPSLFAGTALLVLPPLAGWTAFAL
                     TAAGVLWIRLAAGADFLGGFYTFASMLNTGLMVFGLIWLIRLVTELGETRKRLAEVAVA
                     EERLRFARDLHDLLGMSLSAIALKSELTSRIMDIDTTRASDELLEILGLTRQALTDVRS
                     VASGYRELSLDQESRSAKAVLTAADVQVRLEVEHEDLPATVRTVLAVVLREGVTNVLRH
                     SKVERCEIAVRRTGDGVALDIVNDGVQNGKPPDQNRPGRVEAPGSGITNMSDRVAGLGG
                     ELTAGVEPDGRFRLRAVVPV"
     misc_feature    9403..9405
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(11512..12120)
                     /locus_tag="CVV72_RS19910"
                     /old_locus_tag="CVV72_19825"
     CDS             complement(11512..12120)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005154162.1"
                     /locus_tag="CVV72_RS19910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CVV72_19825"
                     /product="DNA-binding response regulator"
                     /protein_id="WP_034313785.1"
                     /transl_table=11
                     /translation="MAIRVLVAEDMHIVRGALVALLRLEPDIEVVSEVASGDEILAAAR
                     TSRTQVAIIDIDLPGKDGLTAATEIHEQLPEVRTLILTSLGRPGTLRRALAAKVNGFLL
                     KDAPAEKLANAVRGVAAGRRMVDGDLALAAWDTVECPLTPREIDVLRLTAEGRDTLEVA
                     AKAFLSTGTVRNYLTSIVAKLNARNRVDAIRIARESGWI"
     gene            complement(12360..12551)
                     /locus_tag="CVV72_RS19915"
                     /old_locus_tag="CVV72_19830"
     CDS             complement(12360..12551)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016332241.1"
                     /locus_tag="CVV72_RS19915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CVV72_19830"
                     /product="hypothetical protein"
                     /protein_id="WP_219145257.1"
                     /transl_table=11
                     /translation="MQNAVTDNVRSLFAVRGIDTASAGRQVELVIDRFDNWSNRQAGQV
                     FGCFTTVCTTAPPLAEAS"
     misc_feature    complement(12551..12565)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.73"
                     /tool="antismash"
     gene            complement(12835..13380)
                     /locus_tag="CVV72_RS19920"
                     /old_locus_tag="CVV72_19835"
     CDS             complement(12835..13380)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013673458.1"
                     /locus_tag="CVV72_RS19920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CVV72_19835"
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="WP_219145258.1"
                     /transl_table=11
                     /translation="MSYLGSLPTDATLLQVFQRFPAPASKLLDLHELIMRAPSAFDAGE
                     RELIAAYVSGVNDCGYCHGVHTVTAEAFGVPEGLLAAALHDLASAPVDERMKPVLAYVG
                     KLTRTPSRMTDEDAEAVFAAGWDEAALHDAVLVCALFNFMNRMVEGLGIRADAAYAKTS
                     GVRLKEGGYAGLATLLGS"
     gene            complement(13352..13825)
                     /locus_tag="CVV72_RS19925"
                     /old_locus_tag="CVV72_19840"
     CDS             complement(13352..13825)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005154169.1"
                     /locus_tag="CVV72_RS19925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CVV72_19840"
                     /product="DUF6187 family protein"
                     /protein_id="WP_219145259.1"
                     /transl_table=11
                     /translation="MSEPYDSRFTLPSIDDAPSTEAGVILMGLDAGRLLAGVGLARLAD
                     EPALVALAVDQARHDALDLGTEALVEAGILRWRAVRPLIEAGPETTSAGSLRREWEHAT
                     ARVIATVTGLGPASVSCLAACWLRREDVDQFAEQRRAPEQGSAQDVLSRVFAD"
     gene            complement(13818..15137)
                     /locus_tag="CVV72_RS19930"
                     /old_locus_tag="CVV72_19845"
     CDS             complement(13818..15137)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007034656.1"
                     /locus_tag="CVV72_RS19930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CVV72_19845"
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="WP_219145260.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 6.6e-13, bitscore:
                     47.4, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MITFVPEPHLLDSPRGREWPVLPGTRAAVTAEPPPAADVVIVGAG
                     PAGLAVASALWHHGVRDIVVVDRDGRPCGRFFDRIDLLGQRVLRSPYEHHPGVEGYRDC
                     ELLDFARLHWSVLTPVERREIRMAQAGHRSVVPVDVFEAYCRHLAASHHVTERTWRGSV
                     REVLPTSDAVTVRADRFSVTARHVVLCLGEERRSAPDTWWGGGHPPRGVSYWDEPVPGG
                     GGRLAVVGAGLTAAHLISNGLAQGREVHWVVREAGERYQCADVNSSFFRPEGRARFDGV
                     SWSDRLELMGRFRRASIMFEFRPMLEAAEAEGRLIVHRGKAITKVTPGVGLHLEDGSRV
                     SVDHAVLALGTTPSIGDGLMPGEAVLDRGGWPQLDERTFAYIGAPRVFAVGAAAGMALG
                     PAARNIDGHRVATARVAATVAENLRRDLPLRTATKDVARV"
     gene            complement(15146..15631)
                     /locus_tag="CVV72_RS19935"
                     /old_locus_tag="CVV72_19850"
     CDS             complement(15146..15631)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020670857.1"
                     /locus_tag="CVV72_RS19935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CVV72_19850"
                     /product="DUF6423 family protein"
                     /protein_id="WP_034313773.1"
                     /transl_table=11
                     /translation="MAGVADVRRRVLMISGAIDTTEHDISVSVNLPEPGRWQVIKSETN
                     LTDKTWVAMQVVTDEDSTFVNDAETLVLSRQFSKSFMTPDQRRLTFYDGEVRPGEAVLK
                     VYSLDAGGRKPTYSYSRYSPIATDTAEQSRQTLDEMISNGMKQRPVIELIVPVTVIG"
     misc_feature    complement(15800..15814)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.89"
                     /tool="antismash"
     gene            complement(15852..16160)
                     /locus_tag="CVV72_RS19940"
                     /old_locus_tag="CVV72_19855"
     CDS             complement(15852..16160)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016332236.1"
                     /locus_tag="CVV72_RS19940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CVV72_19855"
                     /product="DUF6235 family protein"
                     /protein_id="WP_034313770.1"
                     /transl_table=11
                     /translation="MAMRLQLTSGLQVLEEWAINAPQADRNVVYEALFAVADGSAFLIY
                     DIFGDNREPHQFLFLVKHDLVLRIGIDRADSSFEIVYIGALEQGTPAAAWAEDSEES"
     gene            complement(16253..16402)
                     /locus_tag="CVV72_RS19945"
     CDS             complement(16253..16402)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005154173.1"
                     /locus_tag="CVV72_RS19945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_219145261.1"
                     /transl_table=11
                     /translation="MTAQVRIWVVTDDFDPRGAAEAGAAVTVPEPRQSGENDFPAEHII
                     LGYN"
     gene            16682..16858
                     /locus_tag="CVV72_RS19950"
                     /old_locus_tag="CVV72_19860"
     CDS             16682..16858
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016332235.1"
                     /locus_tag="CVV72_RS19950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CVV72_19860"
                     /product="hypothetical protein"
                     /protein_id="WP_219145262.1"
                     /transl_table=11
                     /translation="MSAAERQRTCAACGGPFAPGERTDLEAVLDGGILYVAVHARHSTY
                     PPRREIEAARRLA"
     gene            complement(16902..17090)
                     /locus_tag="CVV72_RS19955"
                     /old_locus_tag="CVV72_19865"
     CDS             complement(16902..17090)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016332234.1"
                     /locus_tag="CVV72_RS19955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CVV72_19865"
                     /product="acyl-CoA carboxylase subunit epsilon"
                     /protein_id="WP_219145263.1"
                     /transl_table=11
                     /translation="MSPSGMDSACVFRVLRGDPEDAELAALVAVFIALASDAPPPTAPS
                     AWSPLAAPTWRTSTLRW"
     gene            complement(17102..18643)
                     /locus_tag="CVV72_RS19960"
                     /old_locus_tag="CVV72_19870"
     CDS             complement(17102..18643)
                     /EC_number="6.-.-.-"
                     /GO_function="GO:0016874 - ligase activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1059: acetyl-CoA carboxylase, carboxyl transferase,"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007031235.1"
                     /locus_tag="CVV72_RS19960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CVV72_19870"
                     /product="acyl-CoA carboxylase subunit beta"
                     /protein_id="WP_370641964.1"
                     /transl_table=11
                     /translation="MPLLRAQRDELREHIVDGRLDGVRRQHSLGKHTARERLDLLLDPD
                     SFTEVELYRRHRASGLGLAENRPYTDGVIAGSGTIEGRRVFVYAQDFTVFGGSLGEAHA
                     AKIHKVLDLAIATGSPLIGLNDSGGARIQEGVMALDGYGGIFRRQVEASGVIPQISVVL
                     GPCAGGAAYSPALADFVFMVRDTARMYLTGPDVVETVTGERVSHDELGGADVHGASSGV
                     ATVVHDDEESCLADVRYLVSLLPSNYLEPAPRGPSHDAGKDRRPRFAELVPVEPNKPYD
                     MRDVFEELADDGEFFELHERWAPNVLCALARIDGRVVGLVGNQPVVFAGVLDGPASQKA
                     ARFVRFCDAFSIPLVTLVDVPGFLPGVEQEHSGIIRHGAQLLHAYCEATVPRVQVILRK
                     AYGGAYIVMDSRSIGTDVSLAWPTNQIAVMGAEGAVNVLFRKDLAAAADPDALRARLVA
                     EYTEEFMNPQYSAERGLVDDIIDPADTRSAVARALDMLQDKRKAAPQRKHGNHPI"
     gene            complement(18802..18969)
                     /locus_tag="CVV72_RS19965"
     CDS             complement(18802..18969)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005154180.1"
                     /locus_tag="CVV72_RS19965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF6222 family protein"
                     /protein_id="WP_219145265.1"
                     /transl_table=11
                     /translation="MTIDESTPPAPAPTAERPPVVTTMPRLGRGVCWRDIVREIELDEL
                     ERDARLRDAA"
     gene            complement(18985..19557)
                     /locus_tag="CVV72_RS19970"
                     /old_locus_tag="CVV72_19875"
     CDS             complement(18985..19557)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0010181 - FMN binding [Evidence IEA]"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1160: flavin reductase domain protein FMN-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007034651.1"
                     /locus_tag="CVV72_RS19970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CVV72_19875"
                     /product="flavin reductase family protein"
                     /protein_id="WP_192745961.1"
                     /transl_table=11
                     /translation="MGTPDEPSRPVLKRLPSPAARRRLSAQAGLREVMGQFATGVTVLT
                     AGGERAHGMTANAVTSVSLEPPMVLCCVSRAARMHEAIVTAGSYAVTVLASDQKELAKY
                     FADWRRPAGLAQFDSVDWTAGPQTGAPLLDGALAWLECELAEVYEGGDHSIFLGKVVAS
                     SRGTAQDSLVFYSGGYHQIDGRIRASA"
     gene            complement(19559..19999)
                     /locus_tag="CVV72_RS19975"
                     /old_locus_tag="CVV72_19880"
     CDS             complement(19559..19999)
                     /EC_number="3.1.2.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) 4HBT_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005154182.1"
                     /locus_tag="CVV72_RS19975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CVV72_19880"
                     /product="thioesterase family protein"
                     /protein_id="WP_034313761.1"
                     /sec_met_domain="4HBT_2 (E-value: 4.1e-13, bitscore: 48.7,
                     seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MADYYEILHTVGFEETNLVGNVYYVNYVRWQGRCREMFLKEKAPA
                     VLEEVRADLKLFTLKVECEFFAEITAFDELSIRLRLEELTQTQVQFAFDYVHLTDEGER
                     LVARGRQRIACMRGPNTATVPSRVPEQLREALAPYAVDGKGE"
     gene            complement(20001..25829)
                     /locus_tag="CVV72_RS19980"
                     /old_locus_tag="CVV72_19885"
     CDS             complement(20001..25829)
                     /EC_number="6.4.-.-"
                     /NRPS_PKS="Domain: PKS_KS(Enediyne-KS) (5-465). E-value:
                     3.7e-100. Score: 327.7. Matches aSDomain:
                     nrpspksdomains_CVV72_RS19980_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (620-848). E-value: 5.6e-57.
                     Score: 185.3. Matches aSDomain:
                     nrpspksdomains_CVV72_RS19980_PKS_AT.1"
                     /NRPS_PKS="Domain: PKS_KR (1212-1393). E-value: 1.1e-32.
                     Score: 105.3. Matches aSDomain:
                     nrpspksdomains_CVV72_RS19980_PKS_KR.1"
                     /NRPS_PKS="Domain: PKS_DH (1464-1607). E-value: 2.5e-11.
                     Score: 36.2. Matches aSDomain:
                     nrpspksdomains_CVV72_RS19980_PKS_DH.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     ene_KS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1021: malonyl CoA-acyl carrier protein transacylase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005154183.1"
                     /locus_tag="CVV72_RS19980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CVV72_19885"
                     /product="type I polyketide synthase"
                     /protein_id="WP_219145266.1"
                     /sec_met_domain="ketoacyl-synt (E-value: 1.9e-55, bitscore:
                     187.1, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="ene_KS (E-value: 3e-256, bitscore: 849.1,
                     seeds: 19, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 7.6e-55, bitscore: 185.3,
                     seeds: 1682, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSVERISIVGIGLRYPDAGSPEELWENVLAGRRAFRRLPDERMNR
                     EDYYSPDPKAPDRFYAQKAAVLRDWEFDRIKYKVAGSTFRSTDTTHWLALDVAAQALAD
                     AGFPEGEGLPRSATGVVIGNSLTGEFSRANIMRLRWPYVRRTVAAALAERGWAEGDTAA
                     FLHDLEAQYKAPFPEIDEDSLAGGLANTIAGRVCNFFDFGGGGFTVDGACSSSLLSVVT
                     AANALSEGDLDVAIAGGVDLSIDPFEVIGFAKTGALAKREMKVYDADSNGFWPGEGSGM
                     LVLMREEDAIAQGKRIYASIGGWGVSSDGKGGITRPEASGHRLALKRAYDKAGYGVETV
                     SYFEGHGTGTALGDATEIEALSTARRDADPLADRAALSTIKGNIGHTKAAAGVAGLIKA
                     TLAVYHQVIPPATGHFEPHESLIGDSARMYVPTEAGLWPADHPVRAGVSAMGFGGINSH
                     VTVTEAPGAARRKELDERTRSLVAGRQDSELLLLDADDAASLRGRLTGLLEVVPKLSMA
                     ELGDLAATLSAELSGKPVRAAIVATTPEDAERKLAKLLDLLGEGEPEVFSTGDGIFAGS
                     RTKNPKIGFLFPGQGSGRGTVGALRKRFAHADDIYRAAGLSTGADQVATEVAQPRIVTG
                     SLAGLRVLKSLGIEAQTVAGHSLGELTALHWGGALTEREVLKLAKIRGKVMATASDGNG
                     AMAGIAAGPGVAERFAEGEEVVIAGYNAPEQTVLSGPADAIDRVVARARAEGFTATRIN
                     VSHAFHSPAVVPAAEAMTEELAAFDFARLDRPVVSTVTGDVLHAAEDLRDLLRDQVVLP
                     VRFREAAAKVAERSDLVIEVGPGHVLTGLFGEIAPGTPVLAIDTDSPKLSAVLKVAGAA
                     FAFGAPLETSALFDGRIVRSLPVDGEFSFLASPCEAAPSIGADLTRDRVADSAAPAEAP
                     AGTASESGGSSTLDLLRKLASERVELPLEAVTADTHPLDDLHLSSITVGQLVNDVTRAL
                     GRPALEGMPNFATVCLGELAEMIDELAQTAKPADSNQAEVAGVGPWVRPFGVEYVVAPK
                     PSPDLTPGLSTADWSAFAPAGHPLAEPLRAALATSGVGDGVLLCLNADSDAGDVGLFLD
                     AGRAVLAAPNGTRFVVVQHGLGASGLAKTLRLEDPSARTTIVDLADVDPVDPEAVEAAV
                     TTVVAEVAATTDFSEVRYDAAGIRTVPKLAALTPAEAEGTPLGTEDVLLVTGGGKGITA
                     ESALALAKDSGAKLALLGRSDPADDAELSENLGRMAAAGITYRYERADVTDARQVADAI
                     GRVQGEFGPVTAVLHGAGRNEPAALFSLTEESFRKTLAPKIGGLNAVLDAVDKDRIKLL
                     VTFGSIIGRAGLRGEAHYATANDWMTELTVRFGQEHPQARAIALEWSVWSGTGMGEKLG
                     VVSALMRDGITPIPTEEGIEILRQVVGDPTAPSVLVVCGRTGGLATLPVEKRELPLTRF
                     VDRAVVHYPGVELITEADLSAGSDPYLADHLLDGQLLFPAVIGMEAMTQVAKAALGAET
                     LPAPVLSDVEFLRPIIVSPGGSTTIRLAALARDAETVDVVLRSGETGFSADHFRARLRF
                     SRPDPLGETVVRDVALPPVPVDPTTELYGTVLFQGKRFQRVTGYRRASARHAVAEIATG
                     AEVDWFAPFLPQEKLLADPGTRDAMMHAIQCCVPDATLLPQGIERLFLAEPGEQDPEYV
                     LLDARERSQDGDSYLYDLDVRNPDGKLVERWEGLKLRAVRKRDGEGPWVPSMLGSYLER
                     SVERLLGSSRAIVVEPDPVGVSVETTPERRAQTALAAGRAVDAPLEIRYRPDGKPEADG
                     VEVSASHSSDLTLAIAGSGRVACDVETAIERTPEDWAGLLGEDLLSVGELLAADAREPL
                     SVAHTRVWSALECVRKTGDMTQALTVHRVDPDGWAVLSHGGARIATWVTTVNDRPDPVV
                     FAVLQGEEN"
     aSDomain        complement(21009..21437)
                     /aSDomain="PKS_DH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CVV72_RS19980_PKS_DH.1"
                     /evalue="2.50E-11"
                     /label="CVV72_RS19980_PKS_DH.1"
                     /locus_tag="CVV72_RS19980"
                     /protein_end="1607"
                     /protein_start="1464"
                     /score="36.2"
                     /tool="antismash"
                     /translation="AVVHYPGVELITEADLSAGSDPYLADHLLDGQLLFPAVIGMEAMT
                     QVAKAALGAETLPAPVLSDVEFLRPIIVSPGGSTTIRLAALARDAETVDVVLRSGETGF
                     SADHFRARLRFSRPDPLGETVVRDVALPPVPVDPTTELY"
     aSModule        complement(21009..25814)
                     /domains="nrpspksdomains_CVV72_RS19980_PKS_KS.1"
                     /domains="nrpspksdomains_CVV72_RS19980_PKS_AT.1"
                     /domains="nrpspksdomains_CVV72_RS19980_PKS_KR.1"
                     /domains="nrpspksdomains_CVV72_RS19980_PKS_DH.1"
                     /incomplete
                     /locus_tags="CVV72_RS19980"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       complement(21324..21371)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CVV72_RS19980_0005"
                     /evalue="1.30E-03"
                     /label="PKSI-DH_m2"
                     /locus_tag="CVV72_RS19980"
                     /protein_end="1502"
                     /protein_start="1486"
                     /score="11.4"
                     /tool="antismash"
                     /translation="YLADHLLDGQLLFPAV"
     aSDomain        complement(21651..22193)
                     /ASF="KR domain putatively catalyzing L-configuration
                     product formation"
                     /ASF="catalytic triad S,Y,N inconclusive"
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CVV72_RS19980_PKS_KR.1"
                     /evalue="1.10E-32"
                     /label="CVV72_RS19980_PKS_KR.1"
                     /locus_tag="CVV72_RS19980"
                     /protein_end="1393"
                     /protein_start="1212"
                     /score="105.3"
                     /specificity="KR activity: active"
                     /specificity="KR stereochemistry: (unknown)"
                     /tool="antismash"
                     /translation="VLLVTGGGKGITAESALALAKDSGAKLALLGRSDPADDAELSENL
                     GRMAAAGITYRYERADVTDARQVADAIGRVQGEFGPVTAVLHGAGRNEPAALFSLTEES
                     FRKTLAPKIGGLNAVLDAVDKDRIKLLVTFGSIIGRAGLRGEAHYATANDWMTELTVRF
                     GQEHPQARAIALEWSVWS"
     CDS_motif       complement(21717..21803)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CVV72_RS19980_0004"
                     /evalue="4.90E-06"
                     /label="PKSI-KR_m4"
                     /locus_tag="CVV72_RS19980"
                     /protein_end="1371"
                     /protein_start="1342"
                     /score="19.1"
                     /tool="antismash"
                     /translation="LVTFGSIIGRAGLRGEAHYATANDWMTEL"
     CDS_motif       complement(22095..22187)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CVV72_RS19980_0003"
                     /evalue="7.00E-05"
                     /label="PKSI-KR_m1"
                     /locus_tag="CVV72_RS19980"
                     /protein_end="1245"
                     /protein_start="1214"
                     /score="15.5"
                     /tool="antismash"
                     /translation="LVTGGGKGITAESALALAKDSGAKLALLGRS"
     aSDomain        complement(23286..23969)
                     /ASF="(Methyl)Malonyl-CoA specificity inconclusive"
                     /ASF="found active site serine: True, scaffold matched
                     GHGE: True"
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CVV72_RS19980_PKS_AT.1"
                     /evalue="5.60E-57"
                     /label="CVV72_RS19980_PKS_AT.1"
                     /locus_tag="CVV72_RS19980"
                     /protein_end="848"
                     /protein_start="620"
                     /score="185.3"
                     /specificity="substrate consensus: mal"
                     /specificity="PKS signature: Malonyl-CoA"
                     /specificity="Minowa: mal"
                     /tool="antismash"
                     /translation="DQVATEVAQPRIVTGSLAGLRVLKSLGIEAQTVAGHSLGELTALH
                     WGGALTEREVLKLAKIRGKVMATASDGNGAMAGIAAGPGVAERFAEGEEVVIAGYNAPE
                     QTVLSGPADAIDRVVARARAEGFTATRINVSHAFHSPAVVPAAEAMTEELAAFDFARLD
                     RPVVSTVTGDVLHAAEDLRDLLRDQVVLPVRFREAAAKVAERSDLVIEVGPGHVLTGLF
                     GEIAPG"
     CDS_motif       complement(23769..23891)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CVV72_RS19980_0002"
                     /evalue="1.90E-09"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="CVV72_RS19980"
                     /protein_end="687"
                     /protein_start="646"
                     /score="29.5"
                     /tool="antismash"
                     /translation="GIEAQTVAGHSLGELTALHWGGALTEREVLKLAKIRGKVMA"
     aSDomain        complement(24435..25814)
                     /ASF="found active site cysteine: True, scaffold matched
                     GSSS: True"
                     /ASF="found active site histidines: True"
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CVV72_RS19980_PKS_KS.1"
                     /domain_subtypes="Enediyne-KS"
                     /evalue="3.70E-100"
                     /label="CVV72_RS19980_PKS_KS.1"
                     /locus_tag="CVV72_RS19980"
                     /protein_end="465"
                     /protein_start="5"
                     /score="327.7"
                     /tool="antismash"
                     /translation="ISIVGIGLRYPDAGSPEELWENVLAGRRAFRRLPDERMNREDYYS
                     PDPKAPDRFYAQKAAVLRDWEFDRIKYKVAGSTFRSTDTTHWLALDVAAQALADAGFPE
                     GEGLPRSATGVVIGNSLTGEFSRANIMRLRWPYVRRTVAAALAERGWAEGDTAAFLHDL
                     EAQYKAPFPEIDEDSLAGGLANTIAGRVCNFFDFGGGGFTVDGACSSSLLSVVTAANAL
                     SEGDLDVAIAGGVDLSIDPFEVIGFAKTGALAKREMKVYDADSNGFWPGEGSGMLVLMR
                     EEDAIAQGKRIYASIGGWGVSSDGKGGITRPEASGHRLALKRAYDKAGYGVETVSYFEG
                     HGTGTALGDATEIEALSTARRDADPLADRAALSTIKGNIGHTKAAAGVAGLIKATLAVY
                     HQVIPPATGHFEPHESLIGDSARMYVPTEAGLWPADHPVRAGVSAMGFGGINSHVTVTE
                     AP"
     CDS_motif       complement(24759..24806)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CVV72_RS19980_0001"
                     /evalue="9.30E-03"
                     /label="PKSI-KS_m5"
                     /locus_tag="CVV72_RS19980"
                     /protein_end="357"
                     /protein_start="341"
                     /score="9.0"
                     /tool="antismash"
                     /translation="YFEGHGTGTALGDATE"
     gene            complement(26214..27164)
                     /locus_tag="CVV72_RS19985"
                     /old_locus_tag="CVV72_19890"
     CDS             complement(26214..27164)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016332230.1"
                     /locus_tag="CVV72_RS19985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CVV72_19890"
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="WP_219145267.1"
                     /transl_table=11
                     /translation="MAPALVRLALRRALREVRYVRPVPFGRATGLVRDVYRRLERDFGM
                     LAPPVALHSPSPAVLAASWVMLRESLVANGETSRADREVVATLVSRENSCPYCVEVHGM
                     ALDSLGRSSEASAIASGRPVADPRAGAMSTGARAELTAVAFAFHYLNRVVSVFLGSSPL
                     PSSVPDSARAKAKAVLGRFLRPVEEAPPGDSLDLLPSGSGDFAWAVGNPLIVDAFSRAS
                     SAFAALPVSSAVREVVERELSTWDGSPPGLSRAWVDAFDDPGVRLALVVAKAPYQVDDA
                     LVAAAGLTDRELIELVGWASFTAAARAVSVASVGG"
     gene            complement(27167..28819)
                     /locus_tag="CVV72_RS19990"
                     /old_locus_tag="CVV72_19895"
     CDS             complement(27167..28819)
                     /GO_function="GO:0016614 - oxidoreductase activity, acting
                     on CH-OH group of donors [Evidence IEA]"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020629609.1"
                     /locus_tag="CVV72_RS19990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CVV72_19895"
                     /product="GMC family oxidoreductase N-terminal
                     domain-containing protein"
                     /protein_id="WP_219145268.1"
                     /transl_table=11
                     /translation="MTAYDKTDVVIVGSGFGGSIPAYHLAAGGAKVTVLERGPWLETKD
                     FEHDYLLGSSYTRAFDFVVGDGMSVLGGNCVGGGSVVYFAAMPRAPKFVFERHGSIGRR
                     MWPSTITRDSLEPWYDRVSESLPVSKQDWNDVSYAGGLWAAFCDHSGRTANPAPVAVDN
                     DRCVNCNFMMAGCRFDAKRSLLTNYLPAALAHGAKIRPLHEVQRIERIDDGDYRVHFNI
                     VDDEDYRLQSGSGTIDAKIVIIAAGAGATPVILQRSEAALGTMPHGVGRYFSGNGERLN
                     TAIINEERVREVLGLSREDGKVYEANHIGKGPTVANWDKLDGSLPEYERYSLEQLYFPP
                     GLGTILAQVPDGDEPRWFGAQKKEILKKWASWLTIFLMTEDDNEGVFGAPPPTGNAYRI
                     SQQMLGRGPLKYDPTPNTRHGWALADAECKEILEKDGLAKVSPWTNDVVGAYTVHPLAS
                     CRIGDDPKTSALHPNHELREHPGIFVTDSASVPGALTVNPAMTIAALAERSVPGIVRAL
                     QARGVDVTYGAPAPDGSITGRRAVSKLSLVAGS"
     cand_cluster    27336..49609
                     /candidate_cluster_number="3"
                     /contig_edge="False"
                     /detection_rules="((YcaO or TIGR03604) and (((thio_amide
                     and (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /kind="single"
                     /product="azole-containing-RiPP"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    27336..49609
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[37335:39609](-)"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      complement(37336..39609)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="2"
     gene            complement(28816..29373)
                     /locus_tag="CVV72_RS19995"
                     /old_locus_tag="CVV72_19900"
     CDS             complement(28816..29373)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016332228.1"
                     /locus_tag="CVV72_RS19995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CVV72_19900"
                     /product="DUF5987 family protein"
                     /protein_id="WP_125676537.1"
                     /transl_table=11
                     /translation="MDSDEQVKVSTLEAYADTILPGEKRFPGDHAIAGAAEGPGAVVAG
                     ALELLHTDATGVTVGLPYLAQSLNDHAKGYAKEHDLTLDESLPPFVALSFADRTALVRS
                     LTAPGHPEKDGWVSLALFCNMSFDSAAHKHTAEAIAEGHPGLLAMGYTAPDEDGLWRFP
                     KFSYRRELARLHPDTTPSGSPA"
     gene            complement(29379..30731)
                     /locus_tag="CVV72_RS20000"
                     /old_locus_tag="CVV72_19905"
     CDS             complement(29379..30731)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016332227.1"
                     /locus_tag="CVV72_RS20000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CVV72_19905"
                     /product="cytochrome P450"
                     /protein_id="WP_219145269.1"
                     /sec_met_domain="p450 (E-value: 2.7e-89, bitscore: 298.9,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSGAETSRAARLAPPGPPRRATFGLLKKLFTDRLALMSDSAEAH
                     GDVVRIAIGPKTMYLVNHPDLAKHVLADNAANYHKGIGLQEARRALGDGLLTSDGDVWK
                     KQRRTIQPVFQPKRIARQASVVANEVEGLVKRLRDTEGPVEILHEMTGLTLGVLGKTLL
                     DADLGGFTSLGHSFEAVQDQAMFEAVTLSMVPQWAPLKKQLRFRESRADLRRIADELVE
                     QRLANPVENGEDVLSRLIATDGTREQMRDELITLLLAGHETTASTLGWAFHLLDEHPEI
                     AAKLRAEADAVLGDQSPTHDDLHRLPYTARVVEEVMRLYPPVWLLPRVAQADDEIGGYH
                     VPAGSDVVVVPYTLHRHPEFWPEPEKFDPDRFDPDRPSGRPRYAYIPFGAGPRFCIGNS
                     LGVMEAVFVLTMVLRDLELRKLPGYDVVPEAMLSLRVRGGLPMTVHTRNRR"
     gene            complement(30728..31723)
                     /locus_tag="CVV72_RS20005"
                     /old_locus_tag="CVV72_19910"
     CDS             complement(30728..31723)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016332226.1"
                     /locus_tag="CVV72_RS20005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CVV72_19910"
                     /product="enediyne biosynthesis protein"
                     /protein_id="WP_219145270.1"
                     /transl_table=11
                     /translation="MTVMAEQTLTAPKSNKTITALRRFAISITVFNIIGYTVLGFEQPY
                     TYPFIALATAYATEILLEIIGARTQGRGVRFRGNGFKGLVEFLFPAHITGLALNMLTYV
                     NDQVLVMMFGVVVAVGAKWVLQAPVRGRLRHYMNPSNFGITIILLVFPWASIAPPYHFT
                     EQVDSWVGWLIVGIIIVSGTVLNAMLTQRMWLIGAWLITFALQAIIRGLVFDTAIPGAL
                     GMMTGVAFVLYTNYMVTDPGTTPSKPASQVLFGSGVALAYGFFMVVHVAYGLFLATALV
                     CLIRGAFLWGLHFSKKATEKWEAEQAKSAEVTSLPKPAEKPETETGAVAA"
     gene            complement(31720..33684)
                     /locus_tag="CVV72_RS20010"
                     /old_locus_tag="CVV72_19915"
     CDS             complement(31720..33684)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020629613.1"
                     /locus_tag="CVV72_RS20010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CVV72_19915"
                     /product="CRTAC1 family protein"
                     /protein_id="WP_219145271.1"
                     /transl_table=11
                     /translation="MTATLGWLRKQLAGIVALVLMAGLFVVAQLPTVSTAEADTMASKY
                     AFEPLTIALPEAAKSQSIRTVNKDYEHIRAWISSVGAAIAVNDLDGDKLANDLCFVDPR
                     SDQVVITPTPGKGGDRYAPFALDAAPLPMGKYIAPMGCVPADYNEDGRVDLLAYYWGRT
                     PILFLSKPGATKLEPKAYEPVELVPGNNSKNGEYAGPLWNTNAASVGDFDGDGHQDIFI
                     GNYFPDSAVLDDRVQGGVEMNKSMSHADNAGGKYIFRFTGATQGAKPTATFVCDDQAIP
                     ADAQGGWSLAASATDVDGDNLPELYIGNDFGHDRLLYNKSRPGHVEFAEVKGVRGPNDP
                     KSKVLGNDSFKGMGVDFADLDHDGLYDLYVSNITTSWGIEESHFQFMNTAKDTADLRGR
                     LQGGEAPWVDRSAQAGTAWSGWGWDVKIADYNNSGESVITQATGFVKGDVNRWPQLQEL
                     ATSNDELLKHPSFWPNMVAGDDVGGDHTLHFWAKSPDGRYTDLAPRLGLAVPVPTRGIA
                     TGDADGDGKLDFAVARQWEQPIFYRNVSPDAGSYLNLKLVHDKASADGPLKAAGTAAIG
                     AQVTVITPDGKKYMDRVDGGSGHSGKRSHEIQIGLGKVTGPVKVCLQWRDLTGQIRTQE
                     VQLTPGSHTFQLGAQAKEK"
     gene            complement(33681..34625)
                     /locus_tag="CVV72_RS20015"
                     /old_locus_tag="CVV72_19920"
     CDS             complement(33681..34625)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016332224.1"
                     /locus_tag="CVV72_RS20015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CVV72_19920"
                     /product="DUF1702 family protein"
                     /protein_id="WP_255632182.1"
                     /transl_table=11
                     /translation="MITPDVSETSLDKRGFHKKSPAAQELLETVGEKFLLGYAHAVEAR
                     SVDQAEEWLERIPVKYRGFAYEGAGMGYGMLDGLPGGGRRHIEEFLAGPGEKHDYIIYV
                     GVGWAMARLPRFRWPSAEDFDPLLRWLVLDGYGFHQAYFKTAKYIDGQFQDPGFSWPPG
                     NDGYALRAIDQGIGRALWFICGTDVDLVADAIARFPERRHGDLYAGVGLASTYACGVTS
                     DELLKLAEFAGEHRGNLAQGSAFAAEARVRAGLLIPETEVATQAICGLPAERAAAITQE
                     VRPATVVDGELPAFETWRQRIAAEVLNSGGAGK"
     misc_feature    complement(34693..34708)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 22.62"
                     /tool="antismash"
     gene            complement(34796..35698)
                     /locus_tag="CVV72_RS20020"
                     /old_locus_tag="CVV72_19925"
     CDS             complement(34796..35698)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1287: AraC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020629615.1"
                     /locus_tag="CVV72_RS20020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CVV72_19925"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_370641795.1"
                     /transl_table=11
                     /translation="MQLRTVAMAANEKGVTEPGRHPEPASPLQPAVLQAISAMHARYFD
                     PITLSDLAQEVFVSPFHFSRIFAKATGVTPGRYLTAIRLFEAKRLLLTTSLTVSDIVCS
                     VGYSSVGTFTSRFTRAVGMTPTQYRDPEVGELLVAMAPHFQRLPTLEALHSAGMGSPTM
                     RTGTGTISVRVETPRGAGPATVLIGLFAESIPQCGPVAFGGRANVLSADIEIQNVPEGR
                     WTVIGVAEHAAGTAASSFSMGTLPARVDITRYGMVHLRMPMRAPLPTDAPMAITLAGGP
                     TSAGNRMVAPAPGYLRAVA"
     gene            complement(35851..37293)
                     /locus_tag="CVV72_RS20025"
                     /old_locus_tag="CVV72_19930"
     CDS             complement(35851..37293)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005154194.1"
                     /locus_tag="CVV72_RS20025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CVV72_19930"
                     /product="SagB family peptide dehydrogenase"
                     /protein_id="WP_219154031.1"
                     /transl_table=11
                     /translation="MAETIPLWSLTDDSLVEIGEDGSLVVVTRWGEHEFPHAEPLVRES
                     LRRMALGPVSLANVTSSWEPVEREPDLEGELSWTAEGADALRQVLKELGGSVVRSLGLA
                     DGRGPLLSVIPVVLAPVFAPVEIPATRPIRLSRFSSLRSDADGMGLESPSARYRVVLSQ
                     PWAVHVAATLATAKSVGEIVTTTGIDRGVVGAIVSYLVAAGVVQAAENGRFAEDDDPEL
                     RVWSPDELSFHTTSRTWRPGGPADLAGLGNPPVVKAPTGEGPSYSLFRPDLADRAETDP
                     TLTALLEHDHSCPEFTESVLSAEQIGEFLYRGARIRSIGPAHLPNGPAHSASQRPYFSV
                     ACLYELELYVSVNRCSGLDRGIYHYDPLGHRLDLVNDDAADLDEMLDIAMIGGGNHRWP
                     SALITVTARMPRMASVLGGGAYATTLAHVGALQQTLYLVARAMGLAAHAVPVDAGDRVD
                     RALKLDWPAEVGVGECVLDFPA"
     misc_feature    37278..37292
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: strong, score: 20.47"
                     /tool="antismash"
     misc_feature    37331..37347
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 20.59"
                     /tool="antismash"
     gene            complement(37336..39609)
                     /locus_tag="CVV72_RS20030"
                     /old_locus_tag="CVV72_19935"
     CDS             complement(37336..39609)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: YcaO"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: TIGR03882"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: TIGR03604"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Cyanobactin_D_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Goadsporin_CD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NHLP_CD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ThiF"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005154196.1"
                     /locus_tag="CVV72_RS20030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CVV72_19935"
                     /product="TOMM precursor leader peptide-binding protein"
                     /protein_id="WP_219145273.1"
                     /sec_met_domain="Cyanobactin_D_RRE (E-value: 8.5e-24,
                     bitscore: 82.3, seeds: 10, tool: rule-based-clusters)"
                     /sec_met_domain="Goadsporin_CD_RRE (E-value: 2.9e-20,
                     bitscore: 71.1, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="NHLP_CD_RRE (E-value: 1.7e-16, bitscore:
                     58.9, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="ThiF (E-value: 1.2e-05, bitscore: 23.7,
                     seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR03882 (E-value: 1.5e-44, bitscore:
                     150.9, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="YcaO (E-value: 1.4e-92, bitscore: 309.8,
                     seeds: 127, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR03604 (E-value: 1.1e-78, bitscore:
                     263.6, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MREASSTSGSISGGLGFKRHLRVEVRAGNGAYLFSEQGVIAMRGA
                     QVASVAALLDGTRDLDGLLSARPDGMSAEQVTGVLARLVEAGLVTVHVPDEISGDERAL
                     AYWDACGLDASAVAGRQKPATASLTAIGSGIDTSQVASGLAASGIEVVDTASELAIVLC
                     DDYLDPRLAEIDAEHRRTGRPWLLARPSGSQVWIGPIMQPGRSGCWHCLTNRLWGHRHA
                     EACVQEVLGHDGPASFPMPAVPPLTAAASHLISLEASKWLAGHRYPGQQAVWILDTLDL
                     QGRLHELRRRPQCPECGDEGIVAARTAEPVVLREAKKATSGGGGHRTRTPVEVLDRYGH
                     LISPVTGIVKEISRDPRAPAFVNAYHSGGNVARRVRGEAGLQAGLRGENGGKGASPIDA
                     EVGALCEAIERFSANYQGDELRIRDTYRALGEDAVHPNSCMLFDERQYESRVEWNATHS
                     NFQYVPERFDAEAAIDWTPLWSLSRQRRKLMPTAYLYYGVPWECGLTGMRADSNGCAAG
                     SSIEDAILQGLLELVERDAVALWWYNRLPVPGVDIASFDDPWAEEMVGQYARAGRELWV
                     LDLTADLGVPVMVALSRSIVGPRENVMMGFGAHLDPRTALRRAVSELNQLIPAVLANDV
                     ELDDPDAARWLRYATVANQPYLLPAPGRSAKRAADFKFVRRPDVRDDVECLVRRLSVLG
                     METLVLDQTRPDIDLPVVRVVVPGLRPFWSRFAPGRLFDVPVRLGRLAEPTPYERLNPF
                     PMFL"
     aSDomain        complement(39274..39567)
                     /aSDomain="Goadsporin_CD_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing CD fusion protein in a
                     goadsporin cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_CVV72_RS20030_Goadsporin_CD_RRE.1"
                     /evalue="1.00E-22"
                     /identifier="RREFam013.1"
                     /label="CVV72_RS20030"
                     /locus_tag="CVV72_RS20030"
                     /protein_end="112"
                     /protein_start="14"
                     /score="71.1"
                     /tool="antismash"
                     /translation="LGFKRHLRVEVRAGNGAYLFSEQGVIAMRGAQVASVAALLDGTRD
                     LDGLLSARPDGMSAEQVTGVLARLVEAGLVTVHVPDEISGDERALAYWDACGL"
     aSDomain        complement(39301..39567)
                     /aSDomain="NHLP_CD_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing CD fusion protein in a
                     NHLP/Nif11 LAP cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_CVV72_RS20030_NHLP_CD_RRE.1"
                     /evalue="5.80E-19"
                     /identifier="RREFam015.1"
                     /label="CVV72_RS20030"
                     /locus_tag="CVV72_RS20030"
                     /protein_end="103"
                     /protein_start="14"
                     /score="58.9"
                     /tool="antismash"
                     /translation="LGFKRHLRVEVRAGNGAYLFSEQGVIAMRGAQVASVAALLDGTRD
                     LDGLLSARPDGMSAEQVTGVLARLVEAGLVTVHVPDEISGDERA"
     aSDomain        complement(39340..39579)
                     /aSDomain="Cyanobactin_D_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing D protein in a cyanobactin
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_CVV72_RS20030_Cyanobactin_D_RRE.1"
                     /evalue="2.90E-26"
                     /identifier="RREFam007.1"
                     /label="CVV72_RS20030"
                     /locus_tag="CVV72_RS20030"
                     /protein_end="90"
                     /protein_start="10"
                     /score="82.3"
                     /tool="antismash"
                     /translation="ISGGLGFKRHLRVEVRAGNGAYLFSEQGVIAMRGAQVASVAALLD
                     GTRDLDGLLSARPDGMSAEQVTGVLARLVEAGLVT"
     gene            39831..40670
                     /locus_tag="CVV72_RS20035"
                     /old_locus_tag="CVV72_19940"
     CDS             39831..40670
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1041:
                     transcriptional regulator, SARP family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016332220.1"
                     /locus_tag="CVV72_RS20035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CVV72_19940"
                     /product="AfsR/SARP family transcriptional regulator"
                     /protein_id="WP_219145274.1"
                     /transl_table=11
                     /translation="MYTGSRVADTHHGSAPNPIPVTPASPVRFTLLGPLELVRDGIDYA
                     PTTPKLLQVLAMLVMSPGKIVPIDTIVRELWADDPPRSVRTTMHTYVYQLRKCIEENEL
                     APYGETMLATKPPGYVFRIAPEQVDVFEFQELQQRGRELHLRGEHVEAAKAFRSALALW
                     SGPPLANVHCGPVLSAYSVDLVEQRRSTLHLRIEADIAAGMRHELIGELRSLVAANPLD
                     EALHGQLIRVLGRSGRRSDALATYRQVRTRLNYELGVEPCDELQVLHHGLLSEGEPA"
     gene            40711..41397
                     /locus_tag="CVV72_RS20040"
                     /old_locus_tag="CVV72_19945"
     CDS             40711..41397
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1167:
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007034637.1"
                     /locus_tag="CVV72_RS20040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CVV72_19945"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_219145275.1"
                     /transl_table=11
                     /translation="MSIRTYGQFCGLARALEIIGERWSLLIVRDLVLGPKRFTELQAGL
                     PKIPPSTLSARLNELEQSGVLRRRLLPQLDAAVVYELTEYGSELDQIVLDLGLWGARSL
                     GQPSAEDVFTLDSAILSLYTTFRSEKAKGVQVTYELRYPGEMILHAIVEDGALKVAEGA
                     HPGADAVIEPLGPFIKDLLTGDLTAADATRTGKIRLEGAFEYLELFAELFHIPAAPKVT
                     EGIVVR"
     misc_feature    complement(41445..41460)
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: medium,
                     score: 17.23"
                     /tool="antismash"
     gene            41513..42088
                     /locus_tag="CVV72_RS20045"
                     /old_locus_tag="CVV72_19950"
     CDS             41513..42088
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016332218.1"
                     /locus_tag="CVV72_RS20045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CVV72_19950"
                     /product="hypothetical protein"
                     /protein_id="WP_219145276.1"
                     /transl_table=11
                     /translation="MATLDSRPGLLAALNGKYHRAALLSFAVVVVAHWAEHLVQAFQIY
                     ALGWKTPDARGVLGIPFPKLISSEWLHYGYAIVMLVFLFALRKGFAGRSRQWWNLALGL
                     QFWHHIEHLLLLIQAQTGWRLGGGTAPSSIIQLFIPRVELHLFYNTIVTIPMIIAMLVH
                     RKAPAVERELTGCTCSPESRRELATAAS"
     gene            42085..43419
                     /locus_tag="CVV72_RS20050"
                     /old_locus_tag="CVV72_19955"
     CDS             42085..43419
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005154202.1"
                     /locus_tag="CVV72_RS20050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CVV72_19955"
                     /product="copper resistance CopC/CopD family protein"
                     /protein_id="WP_219145277.1"
                     /transl_table=11
                     /translation="MTRRLFALLAVLVAWFGVAVLTAAPASAHVELLSSNPADGARLTS
                     APARVSLTLSENIGIQPNSIKVVDQQGTDVVAGPVFQPGEIAEEVAVALEPDLPDGSYL
                     VEYAFVSADSHPVRGTIAFVIGTGPLITSAGAVSASTGTDPVTDALFTTFRWGSFGGVA
                     LLGGLVFLLVCRPEGRTDPSARKLITAGLWLSGVTAVAGFLLQGPYVTGRGVGALFDPA
                     LIEATLRVAYGKLLLLRLAAIVALAVIVRRLLTGDLPERLRSRYENLGIAAGFIVMLSF
                     SATGHAVADKIMFLSVSADLAHFGAMAVWVGGLIQLAVLLRGRYSASEAEPALARFHPI
                     ATRSIVIMVVSGAYLGFRLVPSVEALWTSAYGIVFLLKLTGFAALLWVANLSRNAVRRG
                     ISGRGGTGVVTADLRKLRISVGVEVLIVAVVLALAAALSSMSPTG"
     gene            complement(43420..44028)
                     /locus_tag="CVV72_RS20055"
                     /old_locus_tag="CVV72_19960"
     CDS             complement(43420..44028)
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016332216.1"
                     /locus_tag="CVV72_RS20055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CVV72_19960"
                     /product="maleylpyruvate isomerase family
                     mycothiol-dependent enzyme"
                     /protein_id="WP_255632183.1"
                     /transl_table=11
                     /translation="MLADHAGAAERVVPACPQWTVRELIAHLAEICDRVITRFGGEACP
                     VPETASAAEVLKLWLERGPEADALLAADGEGKGRGDILVMDAFTHELDLRYALGAPPPG
                     AHAAWLRGFEVLVRGLGDSLGRHGLPGLRIETEGATWIAGTEPVAAVLSGAPVDLYRSL
                     AGRRSPAQIAAMEWLGDPEPWLRAFTWGPFAPPEAEIER"
     gene            44328..44996
                     /locus_tag="CVV72_RS20060"
                     /old_locus_tag="CVV72_19965"
     CDS             44328..44996
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007034633.1"
                     /locus_tag="CVV72_RS20060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CVV72_19965"
                     /product="M protein"
                     /protein_id="WP_219145279.1"
                     /transl_table=11
                     /translation="MEMPGFDLAWRGFDRAQVREFVREVEAELRRVEAERDEALRRGDA
                     LAAELTAAREDNRELKATVDRISRVPIAPDALQERSRRMLELTREEAEEITARAAEEAA
                     KAEAQRKRIAEDFELAMTLRRAEAMRALAARDEAAQARARKLLDDAAEESERLVAEARQ
                     KADVALRLRDDVLKQLVGCRELLTEAGLVLAVPDSPEPEVPVQRRSRPEARTGTEAAAT
                     "
     gene            complement(44997..45359)
                     /locus_tag="CVV72_RS20065"
                     /old_locus_tag="CVV72_19970"
     CDS             complement(44997..45359)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016332214.1"
                     /locus_tag="CVV72_RS20065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CVV72_19970"
                     /product="YciI family protein"
                     /protein_id="WP_034313727.1"
                     /transl_table=11
                     /translation="MKYMIMITMNPTAWDALPEEERDEVVARIDPFMKKLTESGELLGT
                     QALGEPKESTVVRVRDGVPVVTDGPFAESKEYLAGFYLVECDSKERAIEIAGQIPDAHI
                     NAMEIRPVVFSSGDPA"
     misc_feature    45333..45348
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 17.87"
                     /tool="antismash"
     misc_feature    45335..45349
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.18"
                     /tool="antismash"
     gene            45526..45807
                     /locus_tag="CVV72_RS20070"
                     /old_locus_tag="CVV72_19975"
     CDS             45526..45807
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003089374.1"
                     /locus_tag="CVV72_RS20070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CVV72_19975"
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="WP_007034631.1"
                     /transl_table=11
                     /translation="MTGYGTEREAYLKRLRRIEGQIRGLQRMVEEDKYCIDILTQVSAA
                     TKALQSFSLELLDEHLATCVVHAAAAGGEEADLKVREASDAIARLVRS"
     gene            complement(45758..47950)
                     /locus_tag="CVV72_RS20075"
                     /old_locus_tag="CVV72_19980"
     CDS             complement(45758..47950)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1037: heavy metal
                     translocating P-type ATPase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017982164.1"
                     /locus_tag="CVV72_RS20075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CVV72_19980"
                     /product="cation-translocating P-type ATPase"
                     /protein_id="WP_219154032.1"
                     /transl_table=11
                     /translation="MTCASCAARVERKLNKVDGVSATVNYATEKAQVDFPAALSVEDLV
                     GVVESAGYTAQPPKPDEDEDQTGALRTRLVVSAVLAVPVIVLAMVPAWQFTYWQWVSLA
                     LAAPVVTWGAWPFHRPAWTNLRHGAATMDTLISLGVAAATLWSLYALLFGTAGVPGMRH
                     GFELTMQRGSGAGHLYLEVAAGVTTFLLAGRYFEARSKRRSGAALRALLELGAKDVALL
                     KDGAESRVPIGALKTGDEFVVRPGEKIATDGVVTDGGSAVDLSMLTGEAVPVEVGAGDT
                     VVGGTVNAGGRLVVRATRIGADTQLAQMARLVEDAQNGKARVQRLADRVSAVFVPVVIA
                     LAVGTLGFWLGAGSGADAAFTAAVAVLIIACPCALGLATPTALLVGTGRGAQLGILIKG
                     PEVLESTRAVDTVVLDKTGTVTAGKMSLTDLFGADETEVLRLAAAVEHASEHPIARAIV
                     TAAEERLGELPPVDGFRTVEGLGVFGVVEGKTVLAGRPALLDQHGIAVGEEYSQVRTAA
                     EDRGATAVVVAWDGETRGVVVVADTVKPTSAEAVAELKALGLRPVLLTGDNTGSAKAVA
                     AEVGIDEVIAEVLPADKVDVVKRLQAEGRVVAMVGDGVNDAAALAQADLGLSMGTGTDA
                     AIEAGDLTLVRGDLRAAADAIRLSRRTLGTIKGNLFWAFAYNVAALPLAALGLLNPMIA
                     GAAMAFSSVFVVTNSLRLRRFRTGPAGRWRRTPPGP"
     gene            complement(47992..48153)
                     /locus_tag="CVV72_RS20080"
     CDS             complement(47992..48153)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020629626.1"
                     /locus_tag="CVV72_RS20080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_167373499.1"
                     /transl_table=11
                     /translation="MSTAVKVSAFAAALVAVFAVAWAIGSAVGPLDEAPPSPAPTSEHH
                     GHHPGGTP"
     gene            complement(48150..48356)
                     /locus_tag="CVV72_RS20085"
                     /old_locus_tag="CVV72_19985"
     CDS             complement(48150..48356)
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020629627.1"
                     /locus_tag="CVV72_RS20085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CVV72_19985"
                     /product="heavy-metal-associated domain-containing protein"
                     /protein_id="WP_219145280.1"
                     /transl_table=11
                     /translation="MAETTYTVKGMSCGHCASSVTEEVSGIAGVSAVNVDVASGKVTVT
                     SDSPLDVQAVDAAVTEAGYQLVS"
     misc_feature    48402..48417
                     /note="TFBS match to CsoR, Copper-responsive repressor,
                     confidence: medium, score: 27.98"
                     /tool="antismash"
     misc_feature    complement(48402..48418)
                     /note="TFBS match to RicR, Copper-responsive regulator,
                     confidence: medium, score: 26.96"
                     /tool="antismash"
     misc_feature    complement(48403..48418)
                     /note="TFBS match to CsoR, Copper-responsive repressor,
                     confidence: weak, score: 22.0"
                     /tool="antismash"
     gene            48453..49217
                     /gene="cobF"
                     /locus_tag="CVV72_RS20090"
                     /old_locus_tag="CVV72_19990"
     CDS             48453..49217
                     /EC_number="2.1.1.152"
                     /GO_function="GO:0043819 - precorrin-6A synthase
                     (deacetylating) activity [Evidence IEA]"
                     /GO_process="GO:0009236 - cobalamin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="cobF"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TP_methylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020645476.1"
                     /locus_tag="CVV72_RS20090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CVV72_19990"
                     /product="precorrin-6A synthase (deacetylating)"
                     /protein_id="WP_219145281.1"
                     /sec_met_domain="TP_methylase (E-value: 7.5e-26, bitscore:
                     90.3, seeds: 87, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRKISAIGIGAGDPDHLTVQAVRRLNETDVFFVLDKGSEKQDLTA
                     LRQEILDRFVERPGYRVVRAPDPERDRTPDDYRKAVADWHRLRTDVYENMIASLGPDER
                     GAFLVWGDPALYDSTLTLLDAVLARGTVEFEYDVIPGVSSVAALTARHRTTMNQIGRPV
                     QITTGRRLEAGWPADVDDVFVMLDANCTFSQFADTGLEIYWGAYLGTPDELLLSGPLSA
                     GLAAEIRSVRASARSRKGWIMDIYHLRRPARP"
ORIGIN
        1 acaaggcacc atcatgccgg acgcctaccg aagcatgctc gacgaaacca atgccggatc
       61 gcggacgtct tcgttcagct gagtgacgca ccgtccggcc catctccgaa gcagccgcga
      121 ctgtgtggat tttgtcgcgt tagatgaccc gaaatccaca cggtccctac caggaccacc
      181 aagcgcggag ctgggacctc acaagcacgc ccgagtccgc gcggtcccgc gtcatcctca
      241 gaccgcgaac cgctccaacg ccgccagctt ccacgccagt ttcacgtcac tcgagcgatg
      301 tcccgagtcg tcgtcgatca gcagctccgc tccgggccag gcgcgggcga gttcccaagc
      361 cgtgtccacc gggcagctca ggtcccggcg gccgtggatc agcacgccgg gaatgttccg
      421 caacacaccg gcgtcgcgga tcagctcgcc gggttccagc cagcccgcgt gggagtaata
      481 gtgcgtgacg atacgtgcga acgctagttc ccactcgccg atcggaccat tgtggacagt
      541 cacaccagtt tccagtaaca gcacggtgtc ctcccagaca caccaggagc gggcggcttc
      601 ggtccgcacc cgggcgtcgg ggtcttccat gagccgtgcg tacgcggcga ccaggtcgcc
      661 ggtgaggtca ccgcgaaaac gtgcccacgc ttcggggaag aaccggccga cgccgcgata
      721 gagccagtcg atttccgacg gccgtgtcgt gctgatggag ctgacgacga cctcggtgac
      781 ccgctccggg aaccgttcgg cgtaggcgag cgcgagcgtc gtgccccacg aacctccggt
      841 gacgagccag cgttcgatac ccagatgctt ccgcagccgt tccatgtcgg cgacgagatg
      901 atccgtcgtg ttgtgccgca ggtcggtcgc cgggtcgctc gcgtgcgggg tgctgcggcc
      961 gcagccgcgc tgatcgaaca gcaccgcccg gtagcgggcc gggtcgaaca ttcgccgcat
     1021 tcccggcgtg cagccctgcc cggggccgcc gtgcagcatg accgccggct tacctgccgg
     1081 atttccgcag gtctcccagt agacggtgtt gccgtcacct acatcgagca gtccgctgtc
     1141 gtacggctcg gctggtggat acagatcgat catgaagcaa ggctagaccg tcagtgaggc
     1201 cgcgaaacac tttcgccgca acgaagttca gcacaccggc cctttcgtcg ccgcgcccga
     1261 gggggcagat tcagtgatac cggcgaaaac cacggaacgg ggaaccatgt tcacccttgg
     1321 tgtggaagaa gagttcgtcc tgctcgaccc gatggacggc tcggtcgcgc tgcgagcacc
     1381 cgaactgatc gaatgcctcg cccccggccc ggacgtcacc ggtgagctga tgcggttcca
     1441 gatcgagacc gcgaccggcg tctgccgcgg cctcgacgag gtgcgctcgg agctgacgcg
     1501 gctgcggcag atcgtcgcga cggcggcgcg ggccgacggt tgcctgatgg tggcgacggg
     1561 catcccgccc tgcggcctgc gggaagacgc gctcacgccg gagccgcggt accggcggat
     1621 ggcacaggcg ttcccggacc tgatccgtga ggcggggacc tgcgcctgcc atgtgcacgt
     1681 cggcctgccg tcgcgggatc tcggcgcacg ggtcctcgcc gggctgcggc cgtggctcgc
     1741 gccgttgctg gcgctcagcg ccaactcccc ggtcgaaaac ggcgccgact caggatggtc
     1801 gagcaggcgc ttcccgctct gggaccggtg gccgacggcg cgaccacccg aagaatggtc
     1861 cggcgcggcc gcgtacgacc ggagcctcgc ggaggccgtg cgccaccgtg ccgccctcga
     1921 cgcggcgggc gtgtacttct acgcccgcct ttccccgcgt tatcccacgg tcgaggtgcg
     1981 gatcgccgac gtctgcctgt cggtcgacga cgcggtgctg ctcgccgcgc tggtgcgcgg
     2041 actggtcgcg acctgcgccg gaaccacgag accgccgcgt gctcgcggta cccggatcgg
     2101 cgcggcgttg acggcggccg cgcgccgcgg actggacggg ccgggcatcg acgtcttcac
     2161 cggccgggag gccgatcagc gcgatctgct cggcgaactc gtcgagttcg tccggccggc
     2221 actcagggcc gcgggcgacg aggaggacgt cgagcgaggg ttggacgcgc tgttcggcca
     2281 cggcaccggc gcgacccggc aacgccgcct gctcgcggaa gcggcctccc ccggcgagtt
     2341 cgccgcgggg ctcgcgcacg ccacgatgac cgtcccggcc aggtgaggcg accccgcgtc
     2401 acaaccagcc ggactccctg gcgatccgca ccgcgtcgac ccggttgcgg gcgctgagct
     2461 tcgaaacgat cgtcgtcagg tagttccgca cggtaccggc ggacaggaac agctcggcgg
     2521 cgatctcggt cgggtcggag ccgaccgacg ccagccggag cacctcgatc tcgcgggtgg
     2581 tgagcgggca gtcctcgctg tcccaggcgg cgagcgccag atcgccgtcg accacgcgcc
     2641 gtccggcggc gaccccgcgg accgcgttgg cgagcctgtc ggcgggtgcg tccttgcgaa
     2701 ggaagccgtt gaccttcgcg gccagcgccc gtcgcagcgt gccggggctg ccgagcgaag
     2761 tgaggatcag cgtgcggacg ccgggaagcc gctcatgcag ctcggcggcc gcggtgagcc
     2821 cgtccttgcc cggcaggtcg atgtcgatga gcgcgacgtc ggggcgcgcg gactgggcca
     2881 gcgggaggat ttcgtcgccg ctcgcgcatt cggcgacgac ctcgatgtcg ggttccaagc
     2941 cgagcagcgc gaccagggcg ccacggacaa tatgcatgtc ctcggccacc aggaccttga
     3001 tcatcgaccc catctgcctt tccacccgcg tctctccccc gagccgacga tactatcctc
     3061 acacacccgt tccgcgaaat ggaaaccggc ccttgaccgc cgagggggtg cgcggtcgag
     3121 ggccggttct gtgttgtcgc gggaatacgt tcttcgcacc acgccaacac ggtcggggtg
     3181 gttccgacgt gaatgcgcta ccaggaattc tgcgcccacc cggcacgggg atccagtgcg
     3241 cgcaccattg ccggaccgtg gttttcgcat ggtcccgcca ccggacggcg accgtgaaat
     3301 tttcatgtcg ccgcacacag caattcatat cgggcgatga atcaagcact tcaggagtag
     3361 cggtggcgaa cagtagtgtc gaaaccgcaa acatcccaga aatcctcgag cgaaaggacg
     3421 gcacaatgga tgagactgtc cggcgagccg tggagcgagc cattggggcc atgcacgaga
     3481 aactgggcga agagctcact atcgacgaca tcgcccgcgc cgcgaccttc agtaaattcc
     3541 atttcagcag ggtgttccag caggccaccg gcgtctctcc cggccggttc ctgtccgcgc
     3601 tgcgcctcga cgaggccaaa cgcctgctgc tgacgacctc gatctcggtc gccgacatca
     3661 gccaccgcgt gggttacaac ggtgtcggca ccttcagcac gcggttcagc aaccgggtgg
     3721 gcctctctcc ctccgcgtac cgccggcagg gcggtttcca gcaccgcctg gcgggcgaac
     3781 cccttcccgg cgcgaagccg gcgatggtcc gcggtttcgt gtccgcgccg ccggagatct
     3841 cacccggcct cgtgttcgtc ggtctcttcc cgacccgcat tcccgagggc gcgcccgtgc
     3901 ggcacacggt catcgacgtc cccggcccct atcagctgac cgacgtcccg gaaggcacct
     3961 ggcacctcgt cgcgcactgc gtgaccgggc cgctcacgcg ccgcggcacc gggctcaccg
     4021 gccaccacgg gccgatcacc gtggagccgg gcgtcaccgc acggctggcg gacctgcggg
     4081 tgcgccccaa gcgcctgttc gacccgccgg tcctgctcgc cctccccgac ctgcggcatc
     4141 ggccggagcc ggtcaggcgc gcggcctgac cctcacccgc gcgtcaggaa agggtcgttc
     4201 caaggcggaa ggcgtcttga acggcccttt cccgacatcc tggcggcctc aggcggccag
     4261 gcggcccacc gaaggggcga gcccctcccg gatgttctgc cgccacaact cgtacgcggg
     4321 tgtcccgtcc gcggcgtctt cggtgacctc ggtcgagtcg gcgaggtcga cggcctcctc
     4381 gatgctcagc ccggcgagcg tccgcgcggc gaggtgggtg tgccgcggga cgaacgacga
     4441 gaacgtcctc gccttcaccg cgaacacgac gccgaggccg agttcgtcct ggtactcccc
     4501 cgtcgacccc gctgcctcgc gcagcctctc cagtccggcc tggtcgcaac cgcccgcgaa
     4561 ggtcgaggcc agcccgactc cgctccacag gtccgggcgg cgtccggcgg ggaagcggtt
     4621 caccgcctcg gcgaccttca ccggatcgcc gccgttgatg aaccacaacg cccgcccgat
     4681 gccctggtca caggcgcgcg ggaagtaggc gggggcaccc gcccacgggt acggcttggg
     4741 gacgaactgc tcgccgaccc acttgtccgt gtcgaagtag gcgcggtcga aggcgtatcc
     4801 gtcgacggcc agccagctca tcgtcgggtg gaacgggacg ccgtccagct ccggcagcac
     4861 cttcttccac agcggccggg gcagccgggc catcgcgaac ccgatgccga tgtaggtcag
     4921 gaacacgtgc gggagcccgg gcccgctcat cagttcggcc gtgcggtcct tccggccgcc
     4981 gggcatgacg tcgaggatgg tgaacgccat cgccgcgccc tcgtaggcga acccgcgcag
     5041 ctccggctcg accatgtcca gccgccgttc ggcctcccac agcgccggcg cgtcgatccc
     5101 ccattcgaaa ccgcacacca ccgactgcgg gatcgactcc aggcgggcgg tcgccggtgt
     5161 cggcggcacc ccgaaccctc gcccctcgaa gccgaccgaa gccagcgaag gcgcgaacaa
     5221 caccttgcgc agagcaccca gcaatgagct catctcatac gtcctttgtg gatagtggcg
     5281 aattcgcgcg ggaaaccggc tcgtgccgag gacaccacgc cgtgctctcc acccgctcga
     5341 cgcccgatcg agatccgcgc cggtaccgcc gaacaggcca tccccggctt ccggaaagaa
     5401 ggcgggttca cccgttcggc gggcgaattc accggaatgg aaagtactca acagggaatg
     5461 aaatgcactc cgcgcggcct ttttaccggc cccctacatg acggtgcgta atcgatcgct
     5521 cgcagtttca tcaccctcga agtcgccgca tcgccgcagc tcaccaggac ttgatcacac
     5581 cgaagcaccc gccgggaaaa gcgcaacctt gtatcgtgcg aatcagattc actcttacgg
     5641 gtttggtggg tacactgaga gttactgctt ttctggggaa gaggaggtcg gagtgatccg
     5701 agtcctgttg gccgaggaca tgcacatggt ccgcggcgcc ttggtcgccc tgctgaacct
     5761 cgaacgcgac atcgaggtcg tcgcggaggt cggttccggc gacaagatcc ttccgatggc
     5821 ggcggagtac ctgccggacg tcgcgatcat cgacatcgac ctgcccgcca aagacgggct
     5881 cacggccgct tccgagctct gccagcaact tccgagtgtc cgcaccctga tcctcacgtc
     5941 gctcggccgt ccgggcaccg tacgccgcgc gctggacgcg aaggtcaacg gcttcctgct
     6001 caaggacgca cccgccgaca aactcgccaa cgccgtccgc tcggtcgcca ccggccgccg
     6061 ggtcatcgac agcgaactcg ccctgtccgc gtgggaaatc gaggactgcc cgctgacccc
     6121 gcgggaggtc gagatcctcc gcctcgccgc gaacgggcgc acggtcgccg acatcgcggc
     6181 cgaactgttc ctgtcaccgg gaacggtccg gaactatctc gccacggtgg tgacgaaact
     6241 caacgcgcgc aaccgggtgg acgccatccg catcgccgct gattcggact ggctctgact
     6301 ctgatcgcgt cttctctttt gccacaaccg gttcagtacc cgaagtcgtg acgatcgcat
     6361 gcggggcaaa gaaaaaatca tgcctcgtag tgtgtttccg gcactgttcc gaaggttccg
     6421 cctctgtcac cgtcattgag gggggagtcc ggaggggcag gggatgcacg cgatgacgat
     6481 cgaaccgggt gacacggccg cctcggccgg tgcgccgcac ggggtgcgcg cgcggctcct
     6541 cggcccgctc gaactgcaca tcgatgacgc cgatcgcgcg ccgagcacac cgaaactcct
     6601 gcaactgctg gcgatgctgc tcatccgccc cggcaggacg gtccacgtcg actccctcgt
     6661 ccacgagctg tggaacgaag ccccgccgcg cagtgtccgc cggaccctgc acacctacgt
     6721 ccaccacctc cgccgccatc tcgatcccgg cggaaccggc gatctgctgg tcaccagccc
     6781 gcccgggtac cggctcgaga tcgacgcggg agcggtcgac gtgtgggagt tccagcggct
     6841 ccaccgcctc ggccgcgaac tgctcgagga aggcgacaac gcggcggccg cacacgcgtt
     6901 ccgtaccgca ctggacctgt ggtccggtcc cccgctggcg aacatccatt gtggaccgac
     6961 cttggccgcc tacaccgtct atctgctgga gcaccggcgc gacgcccgtg accggtggat
     7021 cgacgccgag atccgcgccg gccggcaccg ggagatgctc ggcgtcctgc ggtcgctgac
     7081 caccgcggac ccgttcgacg aaaccctgca cgcccacctg atccgcgcgc tggggctcag
     7141 cggacgacgc agtgacgccc tggcgtccta cgaatggctg cgctccaggc tcgaggacga
     7201 actgggggtg aaacccagcg ccgaactgcg agagctgcac cgtgaactgc tttccgaggg
     7261 acacccggtc cgctgaccga gcaccaccgc caccagatca aggaatatga ggagtcaagc
     7321 atgaccgctc gcacctatgg ccagttctgc ggcctcgccc gcgccctcga gatcatcggg
     7381 gaacgctggt ccctgctcgt gatccgtgac ctggtactcg gcccgaaacg cttcgacgag
     7441 ctacaacagg gcttgccgaa gatcccgatg agcatcctgt cgacccggct caacgagctg
     7501 gagcggcacg gtgtcgtcca gcgccgggtg ctctcgcagc tcgacgccgg ggtggtctac
     7561 gagctgaccg aatacggcaa cgacctcgac cagatcgtgc tgcagctggg cctgtggggc
     7621 gcccgttcgc tcggcgaccc gacggcggac gacctgttca ccctcgactc ggccgtcctg
     7681 tcgctgtaca ccacgttcca gccggacgcg gcccgtggcg tccactgtgc gttcgagatg
     7741 cactacggcg gcgagatggt catccacgcg gtggtcgagg acggcgcact gaccgcgggc
     7801 gaaggcccgc acccggaccc ggacctcgtc atcgagccgc gcggcccggt catgctgaag
     7861 ctgctgaacg gcgagatgga cgccgcgagc gcgctcacca gcggcgccgt ggccgtcaag
     7921 ggcgacccgg acaagctgga gctgttcacc cggatgttcc acatcccctc cgcgccggcg
     7981 aagaccgaag ggctcgtcac gcattgaggg cgttccagcg gcggggccgg ggccccggtc
     8041 ccgccgttcc tattcgaacc gtgcggtgtc gccggcgcct cgccgcacga tctccggttc
     8101 ccccgacgaa aaatcgatga ccgtggtggg ttcgaccccg cattcaccgg agtcgatcac
     8161 cgcgtccacc acgtgctcca gccgttcctt gatgtcccag ccctgggtca tcggctcctc
     8221 ctggtcgggc agcagcagcg tgctcgacag cagcggctcg ccgagctcgc ccagcagcgc
     8281 ctgggtgacc acgtggtccg ggatccgcac gccgacggtc ttcttcttgg cgtgcagcag
     8341 ccgtcgcgga acctccttgg tggccgggag gatgaacgtg tagctgccgg gagtggacgc
     8401 cttgaccgcg cggaagacgg cgttgtccac gtgcacgaac tggcccagct gagcgaaatc
     8461 ctggcacacc agggtgaaat ggtggcggtc gtccagcttg cggatgctcc ggatgcggtc
     8521 gatgccctgt ctgttcccca gctggcagcc gagggcgaag caggagtccg tcggatacgc
     8581 gatgagcccg tcttcgcgca ggatgtcgac gacctgtccg atcgcgcgcc gttgcggatt
     8641 ttccggatgt acgtcgaaat acctggccat gcgcagagct taaggccacc ggcccccgcc
     8701 cgccgcgaga ggccgcccgg cgtcgcgtac acagtggatc tccccggagc ccgtccgcgg
     8761 ctccggcgtc ttccatagtg gcatgttccg cgacgaaccc ggtggtgcga acagcccaca
     8821 cccgtgcggg tgaccggccg aatttttctg tccccagcag ggaaagcgtc tccctgttcg
     8881 ccgttcttcc tttgtccgaa gggagcaacc ccggtaacga acatgggtta tgatccgaat
     8941 catagcgatg gaaggccgta tcgcggcccg ggccgtcgcg agggggaacg cgaccggatc
     9001 gagccgtctt ctgttatcac tggggtgcct gtgccggacc agctcgctgt gaccgccgaa
     9061 ccgctgggaa ccgccgggat cgaccggcgg ccccgccggg cgctgttcct cgccgggctg
     9121 atcatcaccg tcgtcttcgt caactcctgc ctggtcggtc tcctcggcgt gctgctccgg
     9181 ccgggcgtgg acttctggca tgggctgctc gcggtgcttt acgtcggccc cgtgctggcg
     9241 atccagctgt tgtacttcag ccgtccggcg gtccggctgg acaccaggcg cgcgaaagcg
     9301 atgctggtgg tccaggcctg tctcgcctac ttgcctgcct tgcacttcga cgcggccctg
     9361 acgtcgctga ccacgctcgc cgcgggcagc gcactgctgc tgttacggcc gcggacgggg
     9421 tggacggtgt tcgccgtgct catggcggcc accacctgga tcctgtggac gtacgacgcc
     9481 acctggcacg gagcggtgct cgacagcatc accgcgatcc tctacgccct ggtcgtgtac
     9541 ctgctgacct ggctcgcgcg gctggtgacc gaactgcacc aggccaggac cgagctggcc
     9601 cggcgcgcgg tggcggaaca acggctggcc ttcgccaggg acctgcacga cctgctcggg
     9661 ctcagcctgt ccgcgatcgc gctcaagggc gaactggtgc tccggctgct gcgcaaatcc
     9721 ctggaagggg cccgcgcgga actcgccgag atcaccggga tcgcccagcg gacgctgtcc
     9781 gacgtgcgat cggtggcgag gggttaccgg gaattgtcgc tcgagaagga gtcccggacc
     9841 gcggtgtcgt tgctctcggc ctccaacgtc gccgtgcggg ccgacctcga acccgtcgag
     9901 ctgccggtga agctgcgcac cctgctggcg aaggtgctgc gggaggggat cacgaacgtg
     9961 ctccgctaca cgggcgtcga gcactgcgag atctccgtgc gcgagcacga aggccgggtc
    10021 gtcctggaga tcgtccacga cgggacggcg cacgaggacc tcccggagga aacggcggag
    10081 agcctgcgcg aggtgaccga ggaggtcgcc gggcacggcg gggagctgag cgcgggtccc
    10141 gacgcggcgg gccgatggcg gctgcacgcc gaactcccgg tgcccgacca gatcgagccc
    10201 gcagagaccg tgctggccga ggcgcccggc cactggtccc ggatcgacgc caggaacgtc
    10261 caatggacgc tgacggtgat cttcatcctc ttcggtctct cggcgatgac ccgcgccttc
    10321 atgctgaccg acgacggctg gtccatcgcg ctcatcgccg ggtacctcac cgcgtcgatc
    10381 acgctgcagc tgtcctattt cgcccggccg aacgtccggc tgcgctcgcg gcagagctac
    10441 gcgctgctgt tcgtccaggg ctgcctgatc ttcctgccgc tgatccccct cgggagcgcc
    10501 tgggtgagca tgcccagcct gttcgccggc accgcgctgc tggtgttgcc gcccttggcc
    10561 ggctggacgg cgttcgccct gacggccgcc ggcgtgttgt ggatccggct cgcggcgggc
    10621 gccgacttcc tcggcggctt ctacaccttc gcgtccatgc tgaacaccgg gctgatggtc
    10681 ttcgggctca tctggctgat ccggctggtc accgaactgg gcgagaccag gaagcggctc
    10741 gccgaggtcg cggtcgccga ggaacggctg cgcttcgccc gcgacctgca cgacctgctc
    10801 ggcatgagcc tctcggcgat cgcgctgaag agcgagctga ccagccggat catggacatc
    10861 gacaccacgc gggcctccga cgagttgctg gagatcctcg ggctgacccg gcaggcgctg
    10921 acggacgtcc gctcggtggc cagcggctac cgggaactgt cactggacca ggagtcccgc
    10981 tcggcgaagg cggtgctgac ggccgccgac gtccaggtgc ggctggaggt cgagcacgag
    11041 gacctgccgg cgacggtgcg gacggtgctg gccgtggtgc tgcgcgaggg cgtgacgaac
    11101 gtgttgcggc acagcaaggt cgaacgctgc gagatcgccg tacggcgcac cggtgacggc
    11161 gtcgcgctcg acatcgtcaa cgacggcgtc cagaacggga agccgccgga ccagaaccgg
    11221 ccggggaggg tcgaggcccc gggcagcggc atcaccaaca tgtccgaccg ggtcgccggg
    11281 ctcggcgggg aactgaccgc cggtgtcgaa cccgacggcc ggttccggtt gcgcgcggtg
    11341 gtgccggtct aggcggtgtc ctgtaagtct gttcgatggg cttcgtgatc caggtggttc
    11401 ctggcggtgc gggcggatcg gcctcgtacc gggtcgtact cggccgcgtc cgcccgtgcc
    11461 gccaggggcc gcctgggcgc gaagaccgcg ggcagccttg caggacacgg tctagatcca
    11521 gccggattcc ctggcgatcc ggatcgcgtc gacccggttg cgcgcgttga gtttcgcgac
    11581 gatcgaggtc aggtagttgc gtacggtccc ggtggagaga aacgctttcg ccgcgacctc
    11641 cagcgtgtca cggccctccg cggtcagccg caggacgtcg atctcccgcg gcgtcagcgg
    11701 gcattccacg gtgtcccagg cggcgagggc caggtcgccg tcgaccatgc gcctcccggc
    11761 cgccacgccg cgcacggcgt tggccagttt ctccgcgggc gcgtccttca gcaggaatcc
    11821 gttcaccttg gccgccagcg cccggcggag tgtgccgggc ctgccaaggc tggtcaggat
    11881 cagggtcctg acttcgggga gctgctcgtg gatctcggtg gccgcggtga gaccgtcctt
    11941 gccgggaagg tcgatgtcga tgatcgcgac ctgggtccgt gaagtccgcg cggcggccag
    12001 gatctcgtcg ccggacgcca cttcggacac cacttcgatg tcgggctcca atcggagcaa
    12061 cgccacgaga gcccctctga cgatatgcat gtcttcggcc acgagaactc ggatcgccat
    12121 tacgccgccc ccttcgtgcg cacccccacg acccaacata aacacgcccg tacggaacgc
    12181 gttccaccgt tcgagtgacg catccgacct ctcccggtga ggggcgatac gccgaatgaa
    12241 ccggaccgct acgaattccg cgcctcgccc ggtcgctttc cgtcatcgcg tcgtggctcg
    12301 gcacacgaaa ccggccgccg ctcgcgttcg gggcgcgagc gacggccggt gaggtgccct
    12361 cagctggctt cggccagcgg cggggcggtg gtgcagacgg tggtgaaaca gccgaagacc
    12421 tgcccggcct gccggttgga ccagttgtcg aaccggtcga tcaccagctc gacctggcgc
    12481 ccggccgaag cggtgtcgat cccacggacg gcgaagagcg aacggacgtt gtcggtcaca
    12541 gcgttctgca tcgaaatgac tcccaggctg gtcgcggttt tccttcactg aggaaatcgt
    12601 gcccgcatgc ccgttttccg gccagtgtcg tgcatcatcg cgggaatgtg ctttttacct
    12661 actccggaag cttcttccga ctgcgccatt cccgcgatct tcgccatcga atggagtaac
    12721 gtgcagcttt cacggtgacg gaacgcggtg aagtgaattc tttacgccac catcaccgac
    12781 agtcacggga ataccccgaa cagaccaatc gattcgtcca ctgtggacag cggatcagga
    12841 gccgagcagg gttgccaggc cggcgtatcc gccctctttc aggcgcacgc cggacgtctt
    12901 cgcgtacgcg gcgtcggcgc ggatcccgag cccttcgacc atccggttca tgaagttgaa
    12961 cagggcgcac acgagcaccg cgtcgtgcag cgcggcctcg tcccagcccg ccgcgaagac
    13021 ggcctcagca tcctcatcgg tcatccgaga cggcgtacgc gtcagcttgc ccacataggc
    13081 cagcacgggc ttcatgcgct cgtccacggg cgcggaggcg aggtcgtgga gcgcggcggc
    13141 cagaagtcct tccggcacac cgaaagcctc ggcggtgacg gtgtggaccc cgtggcagta
    13201 cccgcagtcg ttgacgccgg aaacgtaggc cgcgatcagc tcccgctccc ccgcgtcgaa
    13261 cgccgacggc gcccgcatga tcagctcgtg caagtccagc agcttcgacg ccggagcggg
    13321 aaacctctgg aacacctgca gcaacgtggc gtcagtcggc aaagacccga gataggacat
    13381 cttgtgcgct cccctgctcc ggcgcccgcc tctgttcggc gaactggtcg acgtcctcgc
    13441 gccgcagcca gcaggccgcg aggcaggaca ccgatgccgg tcccagcccg gtcaccgtgg
    13501 cgatgacccg cgcggtcgcg tgttcccatt ctcggcgcag ggaacccgcc gacgtcgtct
    13561 ccggacctgc ttcgatcaac gggcggaccg cgcgccagcg aaggatcccg gcctccacca
    13621 acgcttcggt gccgagatcg agcgcgtcgt gccgggcttg gtccacggcg agggcgacca
    13681 gcgcgggctc gtcggcgagc cgggcgagcc cgacgccggc gagcaggcgt ccggcgtcca
    13741 gtcccatcag gatcaccccc gcctcggtcg agggagcgtc gtcgatcgac ggcagggtga
    13801 agcgggagtc gtagggctca gacacgggcg acgtccttcg tggccgtccg gagcggaaga
    13861 tcccggcgca ggttctcggc gacggtggcc gcgacccggg cggtggcgac gcggtgaccg
    13921 tcgatgttgc gggcggcggg acccagcgcc atccccgcgg ccgcgccgac ggcgaagacc
    13981 cggggcgcgc cgatgtaggc gaaggtgcgt tcgtccagct gcggccagcc gccgcggtcg
    14041 aggacggcct cgccgggcat caagccgtcc ccgatcgacg gcgtggtgcc gagcgccagt
    14101 acggcgtggt ccacggacac ccgcgaaccg tcttcgaggt ggaggccgac gccaggggtc
    14161 accttcgtga tcgccttgcc gcgatgcacg atcagccgtc cttcggcttc ggccgcttcg
    14221 agcatcgggc ggaactcgaa catgatcgac gcgcgccgga accggcccat cagttcgagc
    14281 ctgtcggacc agctcacccc gtcgaagcga gcgcggcctt ccggccggaa gaacgacgag
    14341 ttgacgtcgg cgcactggta gcgttcgccc gcttcacgga ccacccagtg cacctcgcgg
    14401 ccctgggcga gcccgttgga gatcaggtgc gcggcggtga ggcccgcgcc gacgacggcg
    14461 aggcgcccgc cgccgccggg aacgggttcg tcccagtagc tcacgccgcg cggcggatga
    14521 ccaccgcccc accacgtgtc cggggcggac cggcgctcct cgccgaggca cagcacgaca
    14581 tgccgcgcgg tgacggagaa ccgatcggcg cgcacggtga cggcgtcaga agtcggcagc
    14641 acctcccgga ccgaaccgcg ccaggtccgc tcggtgacgt gatgactcgc cgcgagatga
    14701 cggcagtagg cctcgaagac gtcgacgggg accaccgagc ggtgcccggc ctgcgccatg
    14761 cggatctccc ggcgttccac cggcgtgagc accgaccagt gcagccgggc gaagtccagg
    14821 agttcgcagt cgcggtagcc ctcgacgccg gggtggtgtt cgtacggcga ccgcagcaca
    14881 cgctggccga gcagatcgat gcggtcgaag aaccggccgc agggacggcc gtcgcggtcg
    14941 acgaccacga tgtcgcggac tccgtgatgc cacaacgcgg aagcgaccgc gagcccggcc
    15001 gggcccgccc cgacgatgac cacgtcggcg gcgggcggcg gttcggcggt gaccgccgcg
    15061 cgggtgccgg gaagcaccgg ccactcacgc ccgcgcggcg aatcgaggag atggggttcc
    15121 gggacgaagg tgatcaccgg cgtactcagc cgatcacggt caccgggacg atcagctcga
    15181 tcacgggacg ctgcttcatc ccgttgctga tcatttcgtc cagtgtctgc cgggactgct
    15241 cggcggtgtc cgtcgcgatc gggctgtagc gggagtacga gtaagtcggc ttccgcccgc
    15301 ccgcgtcgag cgagtacacc ttgagcaccg cttcgccggg ccggacttca ccgtcgtaga
    15361 aggtgaggcg gcgctgatcc ggcgtcatga aggacttcga gaactggcgg gagaggacca
    15421 gcgtttcggc gtcgttgacg aaggtcgagt cctcgtcggt gacgacctgc atcgcgaccc
    15481 aggtcttgtc ggtcaggttg gtctcggact tgatcacctg ccagcggccc ggttccggga
    15541 gattgacact caccgagatg tcgtgctcgg tggtgtcgat cgccccggag atcatcagca
    15601 cccgccgccg gacgtcggcg accccggcca tctgaatgtc acgtgcgcgt acccgagtgg
    15661 aaacatccaa tcccgggaat tcaggtgatg acatcttgca cacctccaag accttgatat
    15721 cgcaattcaa tccccggcat gatcccccca gccgcaaaca ccggaagaat ttcacgctga
    15781 actgggcgat gtcaagatga ggaacacatg atccactgcc gccgggactg gtccgttcgg
    15841 cggtaccggg gtcaggattc ttcggaatcc tcagcccagg ccgccgctgg tgtgccctgc
    15901 tccagcgccc cgatgtagac gatctcgaac gaggaatcgg cccgatcgat cccgatacgg
    15961 aggacgaggt cgtgtttcac cagaaatagg aactgatgcg gttcccggtt gtctccgaaa
    16021 atgtcgtaga tgaggaaggc ggaaccgtcc gcaaccgcga acagtgcttc gtagacgaca
    16081 ttgcggtcgg cctgcggagc attgatcgcc cattcttcca acacctgcaa acccgacgtg
    16141 agctggaggc gcatagccat ccggaggcct cctcgtggtc tggcgggttc gcgggcgatc
    16201 ttcatcgtcg cgcgcgcgat acccggcggt cttcttcgtc tgtgctgggt ggctagttgt
    16261 aaccgaggat gatgtgctcg gccgggaaat cgttttcgcc ggactgcctc ggctccggga
    16321 cggtcaccgc cgcgccggcc tccgcggccc cgcgcgggtc gaaatcatcg gtcacgaccc
    16381 aaattcgcac ctgcgccgtc atgacgttcc tcccggcctt cgatgaacga ctcacttgac
    16441 aaccaaggat ggacccgtcc gatcgtgccg cgatcgagga tcgacggagg tctcgatgag
    16501 caaaggaaaa gtcgccgccg aagggctgcc ggtagtgccc ttgagatacc tcgaaaccca
    16561 gggagcgcac catgaccgaa cgtctcgacc cgtacgagat ctacgccgac gacgaggtcg
    16621 acgtcgattt gctgggcctg tcgtggcccg acccggcggt ccccgagcag cgggatcggc
    16681 aatgagcgcc gcggagcggc agcggacctg tgcggcctgc gggggaccgt tcgcgcctgg
    16741 ggagcgaacg gatctggagg ccgtgctcga cggagggatc ctctacgtcg cggtgcacgc
    16801 ccgccacagt acgtatccgc cgcggcggga gatcgaggcc gcgcggcgtc tcgcatgagc
    16861 acgcgcgagt ccgtgaagga ggccttcaca gactcgcgtg ttcaccagcg cagcgtcgag
    16921 gtacgccagg tcggggcggc gagaggcgac caggcggaag gcgccgtggg cgggggcgcg
    16981 tcggaggcca acgcgatgaa gacggcgacg agtgccgcca gctcggcgtc ttccgggtcg
    17041 ccgcgcagga cccggaagac gcacgcactg tccattccgg acggtgacat ggttcccccg
    17101 ttcagatcgg gtggttgccg tgcttgcgct ggggcgccgc cttccgcttg tcctgcagca
    17161 tgtccagcgc cctggcgacg gcggaccggg tgtccgcggg gtcgatgatg tcgtcgacca
    17221 gcccgcgttc ggccgagtac tgcgggttca tgaactcttc ggtgtattcg gcgaccaggc
    17281 gcgcgcgcaa cgcgtccgga tcggccgcgg cggcgagatc cttgcggaac agcacgttga
    17341 ccgcgccctc ggcgcccatc acggcgatct ggttggtcgg ccacgccagc gagacatcgg
    17401 tcccgatgga ccgcgagtcc atcacgatgt acgcgccgcc gtacgccttg cgcaggatga
    17461 cctggacgcg cggcacggtc gcctcacagt aggcgtgcag cagctgggcc ccgtgccgga
    17521 tgatccccga gtgctcctgc tcgacccccg gcaggaagcc ggggacgtcc acgagcgtca
    17581 ccagcgggat gctgaacgcg tcgcagaacc gcacgaaccg cgccgccttc tgcgacgccg
    17641 ggccgtcgag cacaccggcg aacaccaccg gctggttgcc gaccaggccg accacccgcc
    17701 cgtcgatccg cgcgagcgcg cacagcacgt tcggagccca tcgctcgtgc agttcaaaga
    17761 actcgccgtc gtcggccaat tcttcgaaca cgtcgcgcat gtcgtacggc ttgttcggct
    17821 ccaccgggac gagttcggcg aaccggggcc gccggtcctt gcccgcgtcg tgcgacggcc
    17881 cacggggcgc gggctccagg tagttcgacg gcagcagcga caccagatac cggacgtcgg
    17941 cgaggcagct ctcctcgtcg tcgtgcacca cggtcgccac gccggacgac gcgccgtgca
    18001 cgtccgcgcc ccccagttcg tcgtggctga cccgttcccc ggtcacggtc tcgacgacgt
    18061 ccggcccggt caggtacatg cgggcggtgt cgcgcaccat gaagacgaaa tccgcgagcg
    18121 cgggcgagta cgccgccccg cccgcgcacg gccccagcac cacgctgatc tgcgggatga
    18181 cgccggacgc ctcgacctgg cggcggaaga tgccgccgta gccgtcgagc gccatgacgc
    18241 cttcctggat ccgggctccc ccgctgtcgt tgagcccgat gagcggcgag ccggtggcga
    18301 tcgccagatc cagcaccttg tggatcttcg ccgcgtgcgc ctcgccgagc gaaccgccga
    18361 agacggtgaa gtcctgcgcg tagacgaaca cccgccggcc ctcgatggtg cccgagccgg
    18421 cgatgacgcc gtcggtgtac ggccggttct ccgccagccc gagcccactc gcccgatgcc
    18481 gccggtacag ctcgacctcg gtgaaggaat cgggatccag caacagatcc agccgttcac
    18541 gcgcggtgtg cttgcccagc gagtgctgcc gacggacgcc gtcgagccgt ccgtcgacga
    18601 tgtgctcacg cagctcgtcg cgctgggcgc gcagcaacgg catcgtcggt tgcggcggat
    18661 ggaccggttc ggcgccgcgg gcgaggggga tcacctgccc gtcggtcgcc ctggggaccc
    18721 gggggcgccg caaccggtcc tccggcagcg gcaccacctc ggaatcctcc gtgcgctgag
    18781 cacccggatc accttgcagg gtcacgccgc gtcccgtagc cgggcatcac gctcgagttc
    18841 gtcgagctcg atctcgcgca cgatgtcgcg ccagcacacc ccccgtccga gccggggcat
    18901 cgtggtcacc accggcggcc gctcggccgt gggcgccggt gcgggcgggg tggattcgtc
    18961 gatggtcatg acattccttt ctggtcaggc cgatgcccgt atccggccgt cgatctggtg
    19021 gtagccgccg ctgtagaaga ccagcgagtc ctgggcggtg cctcggctgg aggcgaccac
    19081 cttgccgagg aagatcgagt ggtcaccgcc ttcgtagact tcggcaagct cgcattccag
    19141 ccacgccagc gcgccgtcga gcagcggggc gccggtctgc ggccccgccg tccagtccac
    19201 cgagtcgaac tgggcgagcc cggccgggcg gcgccagtcg gcgaagtact tcgccagttc
    19261 cttctgatcc gacgccagca ctgtgaccgc gtacgaaccc gccgtcacga tcgcttcgtg
    19321 catccgggcg gcgcgggaaa cgcagcacag caccatcggc ggctccagcg acacggaggt
    19381 gacggcgttg gcggtcatcc cgtgggcccg ttcgcccccg gcggtcaaca cggtgacccc
    19441 ggtggcgaac tggcccatca cctcccgcaa cccggcctgc gcggacaacc ggcggcgggc
    19501 ggcgggcgac ggcaggcgtt tcagcacggg ccgcgaaggc tcgtccggcg tgcccacgtc
    19561 attccccctt gccgtcgacc gcgtacgggg ccagcgcctc acgcagctgc tcgggcaccc
    19621 ggctgggcac cgtggccgtg ttcgggccgc gcatgcacgc gatccgctgc cttccgcggg
    19681 ccaccagccg ctcgccctcg tcggtgaggt ggacgtagtc gaaggcgaac tggacctggg
    19741 tctgggtcag ctcctccagt cgcagcctga tggacagctc gtcgaacgcg gtgatctcgg
    19801 cgaagaactc gcactccacc ttgagcgtga agagcttgag gtcggcgcgg acctcttcga
    19861 gtaccgcggg cgccttctcc ttcaggaaca tttcgcggca ccggccctgc cagcgcacgt
    19921 agttcacgta gtagacgttg cccaccaggt tggtctcttc gaacccgacg gtatgcagga
    19981 tctcgtagta gtcggccatg tcagttctcc tctccctgga gcaccgcgaa gacgacggga
    20041 tcgggccggt cgttgacggt cgtcacccag gtggcgatgc gggcaccgcc gtgggaaagc
    20101 accgcccagc cgtccgggtc gacccggtgc acggtgagcg cctgtgtcat gtccccggtc
    20161 ttgcgcacgc attccagcgc gctccagacc ctggtgtgcg cgaccgaaag cggctcgcgg
    20221 gcgtccgcgg cgagcagttc gcccaccgac agcagatcct cgccgagcag ccccgcccag
    20281 tcttcgggcg tccgctcgat cgcggtttcg acgtcgcacg cgacccgccc gctgcccgcg
    20341 atcgcgaggg tgaggtcgga gctgtgcgac gcgctcacct cgaccccgtc ggcttccggt
    20401 ttcccgtccg ggcggtagcg gatctcgagc ggggcgtcga cggcgcggcc ggcggccagc
    20461 gccgtctgcg cccgccgttc cggcgtggtc tccacggaga cgcccaccgg gtccggttcg
    20521 acgacgatcg cgcgagacga gccgagcagc cgttcgacgg aacgctccaa ataggacccg
    20581 agcatcgacg ggacccaagg cccttcgccg tcccgcttgc gcaccgcgcg cagcttcagc
    20641 ccttcccacc gctcgaccag cttcccgtcg gggttgcgga cgtcgaggtc gtagaggtag
    20701 ctgtcgccgt cctgcgaacg ctcgcgggcg tcgaggagca cgtactccgg gtcctgctcg
    20761 ccgggttcgg cgaggaacag ccgctcgatc ccttgcggca gcagcgtcgc gtccggcaca
    20821 cagcactgga tcgcgtgcat catcgcgtcg cgggtgccgg ggtcggccag cagcttctcc
    20881 tgcgggagga acggcgcgaa ccagtcgacc tcggcgccgg tcgcgatctc cgcgaccgcg
    20941 tgccgcgcgc tggcccgccg gtagccggtg acccgctgga atcgcttgcc ctggaacagg
    21001 accgtgccgt acagctcggt cgtcgggtcg accgggacgg gcggcagcgc gacgtcgcgg
    21061 acgacggtct cgccgagcgg atccggccgg gagaaccgca gccgggcccg gaagtggtcg
    21121 gcgctgaacc cggtctcccc gctgcgcagc accacgtcca ccgtttcggc gtccctggcc
    21181 agcgcggcga gccggatcgt ggtcgaccca cccggtgaga cgatgatcgg acgcaggaac
    21241 tcgacgtcgg agagcaccgg cgccggcagt gtttccgcgc cgagggcggc cttcgcgacc
    21301 tgggtcatcg cctccatgcc gatcaccgcg gggaacagca gctgaccgtc gagcaggtgg
    21361 tcggccagat acgggtcgct gcccgcggac aggtcggcct ccgtgatcag ctcgacaccc
    21421 gggtagtgca cgacggcccg gtcgacgaag cgggtcagcg gcagttcgcg cttctccacc
    21481 ggcagggtgg ccagcccgcc ggtccggccg cagacgacca gtaccgacgg ggccgtcgga
    21541 tcgccgacga cctggcgaag gatctcgatg ccttcttcgg tcgggatggg ggtgatgccg
    21601 tcgcgcatca gagcgctgac gacaccgagc ttttcgccca tgcccgtccc ggaccagacc
    21661 gaccactcga gggcgatcgc cctggcctgg gggtgctcct ggccgaaccg cacggtcagt
    21721 tcggtcatcc agtcgttggc cgtggcgtag tgcgcctcac cgcgcaggcc cgcccgtccg
    21781 atgatgctgc cgaaggtcac cagcagcttg atcctgtcct tgtcgacggc gtcgaggacg
    21841 gcgttgagac cgccgatctt cggggccaac gtcttgcgga agctctcctc ggtcaaggag
    21901 aacagcgcgg cgggctcgtt gcggcccgcg ccgtgcagca ccgcggtgac cgggccgaac
    21961 tcgccctgca cgcggccgat cgcgtcggcg acctgccggg cgtcggtgac gtcggcgcgt
    22021 tcgtagcggt aggtgatacc cgccgccgcc atgcggccga ggttctccga cagttcggcg
    22081 tcgtcggccg ggtcgctccg gccgagcagc gcgagtttcg cgccggagtc cttggccagc
    22141 gccaacgcgc tctcggcggt gatgcccttg ccgccgccgg tgacgagcag gacgtcttcg
    22201 gtccccagcg gggtcccttc ggcctcggca ggggtcaggg cggccagctt cggcaccgtg
    22261 cggatcccgg cggcgtcgta gcggacctcg ctgaagtcgg tggtcgccgc cacttcggcg
    22321 accacagtgg tcaccgcggc ttcgacggcc tcggggtcga ccgggtcgac gtcggcgaga
    22381 tcgacgatcg tggtgcgggc cgacgggtcc tccagccgca gcgtcttcgc caggccggag
    22441 gcaccgagcc cgtgctgcac cacgacgaac cgcgtgccgt tgggcgcggc cagcacggcg
    22501 cggcccgcgt ccaggaacag gccgacgtcg ccggcatcgc tgtccgcgtt caggcagagg
    22561 aggacaccgt cgccgacacc cgaggtggcc agtgccgcgc gcagcggctc cgccagcgga
    22621 tgcccggccg gggcgaacgc cgaccagtcg gcggtggaca ggcccggcgt gagatcgggc
    22681 gacggcttcg gcgcgacgac gtactcgacc ccgaacggcc ggacccacgg tccgacgccg
    22741 gcgacctcgg cctggttgct gtcggcgggt ttggcggtct gggcgagttc gtcgatcatc
    22801 tcggcgagtt cgccgagaca gacggtcgcg aagttcggca tgccctccag cgcgggacgg
    22861 ccgagcgccc gggtcacgtc gttgacgagc tggccgaccg tgatcgacga aaggtgcagg
    22921 tcgtcgagcg gatgcgtgtc ggcggtgacc gcttcgagcg gcagttcgac ccgctcggaa
    22981 gcgagtttgc gcagcaggtc gagggtactg ctgccaccgc tttccgaggc cgttccggcc
    23041 ggggcttcgg cgggcgcggc cgagtcggcg acccggtcgc gggtcaggtc ggcaccgatg
    23101 gacggcgcgg cctcacacgg gctggcgagg aacgagaact ccccgtccac cggcagggac
    23161 cgcacgatcc ggccgtcgaa cagcgcggag gtctccagcg gggcgccgaa cgcgaacgcg
    23221 gcgcccgcga ccttcagcac cgcggacagt ttcgggctgt cggtgtcgat cgcgagcacc
    23281 ggcgtgccgg gcgcgatctc gccgaacagg ccggtgagca cgtggccggg gccgacctcg
    23341 atcaccaggt cgctgcgctc ggcgaccttc gcggccgcct cacggaagcg gaccggcagg
    23401 accacctggt cccgcagcag atcgcgcagg tcctcggcgg cgtgcaggac gtcaccggtc
    23461 accgtcgaga cgacgggccg gtcgagcctg gcgaaatcga acgcggcgag ttcctcggtc
    23521 atcgcctcgg cggccgggac gaccgccggc gagtggaacg cgtgcgagac gttgatgcgg
    23581 gtggcggtga agccctccgc gcgggcacgg gcgaccacac ggtcgatcgc gtccgccggt
    23641 ccggaaagga cagtctgctc gggcgcgttg tagcccgcga tgacgacctc ttcgccctcg
    23701 gcgaaccgct cggcgacccc gggcccggcg gcgatccccg ccatggcgcc gttcccgtcg
    23761 ctcgcggtcg ccatcacctt gccgcggatc ttggccagct tgaggacttc gcgttcggtg
    23821 agcgcgccac cccagtgcag ggcggtgagt tcgccgaggc tgtggccggc gaccgtctgc
    23881 gcctcgatgc cgaggctctt caggacacgg agcccggcga gcgaaccggt gacgatgcgc
    23941 ggctgcgcga cctccgtggc gacctggtcg gcgccggtcg aaaggccggc cgcgcggtag
    24001 atgtcgtcgg cgtgggcgaa gcgcttgcgc agcgcgccga ccgtgccgcg tccggaaccc
    24061 tggccgggga acaggaaacc gatcttcggg ttcttggtgc gagagcccgc gaagatgccg
    24121 tcgccggtgg agaagacctc cggctccccc tcgccgagga ggtcgagcag cttggccagc
    24181 ttgcgctcgg cgtcctcggg agtggtcgcg acgatcgccg cgcggaccgg tttcccggac
    24241 agttccgcgg aaagcgtggc cgcgaggtcc ccgagctccg ccatcgagag cttcggcacg
    24301 acttccagca gaccggtcag cctgccgcgc agcgacgcgg cgtcgtcggc gtcgaggagc
    24361 agcagttcgc tgtcctgccg tccggcgacc agcgagcggg tccgctcgtc gagttccttg
    24421 cgccgggccg cgcccggcgc ctcggtgacg gtgacgtgcg agttgatacc accgaagccc
    24481 atcgccgaga cacccgcgcg gaccgggtgg tccgcgggcc acagcccggc ctcggtcggg
    24541 acgtacatcc gcgcggagtc gccgatcagc gactcgtgcg gctcgaagtg accggtcgcg
    24601 ggcgggatga cctggtggta gaccgccagc gtcgccttga tcagcccggc gaccccggcc
    24661 gcggccttgg tgtggccgat gttgcccttg atcgtgctca gcgcggcgcg gtcggcgagc
    24721 ggatcggcgt cgcggcgggc ggtggagagc gcctcgatct cggtggcgtc gcccagcgcg
    24781 gtcccggtgc cgtgcccctc gaagtaggaa acggtctcga ctccgtagcc ggccttgtcg
    24841 taggcccgct tgagcgcgag acggtgaccc gacgcctcgg gccgggtgat gccgcccttg
    24901 ccgtcggagg agacgcccca gccgccgatg ctggcgtaga tccgcttgcc ctgcgcgatc
    24961 gcgtcctcct cgcgcatcag cacgagcatg ccggaaccct cgccgggcca gaacccgttg
    25021 gagtcggcgt cgtagacctt catctcccgc ttggcgagcg cgccggtctt ggcgaaaccg
    25081 atcacctcga acgggtcgat cgacaagtcg acaccgcccg cgatggcgac gtcgaggtca
    25141 ccctcggaaa gcgcgttcgc cgccgtcacc acggaaagca gcgacgacga gcaggcgccg
    25201 tccacggtga acccgccgcc gccgaagtcg aagaagttgc agacgcggcc ggcgatcgtg
    25261 ttcgccagcc cgcccgcgag cgagtcctcg tcgatctccg ggaacggggc cttgtactgc
    25321 gcctccaggt cgtggaggaa cgcggcggtg tcaccctcgg cccagccgcg ctcggcgagc
    25381 gcggccgcga cggtgcggcg cacgtacggc cagcgcagcc gcatgatgtt ggcgcgcgag
    25441 aactcaccgg tgaggctgtt gccgatgacc acgccggtgg cggaccgcgg cagcccctcg
    25501 ccctcgggga accccgcgtc cgccagcgcc tgcgcggcga cgtcgagcgc cagccagtgc
    25561 gtggtgtcgg tcgaccggaa cgtgctgccc gcgaccttgt acttgatccg gtcgaattcc
    25621 cagtcgcgga gcaccgcggc cttctgggcg tagaaacggt ccggcgcctt ggggtcgggc
    25681 gagtagtagt cctcgcggtt catccgctcg tcgggcagtc tccggaacgc cctgcggccg
    25741 gcgaggacgt tctcccacag ttcttccggg gaaccggcgt ccgggtatcg gagaccgata
    25801 ccgacaatcg aaatccgctc aacgctcatg ccaccgcact cccctagctc tcaagactca
    25861 agtcacggaa tccggtcccg gcgccgggct ctgtccccag aaccgcggcc gccgtccgtt
    25921 cgcgcagtcc ggtcaagcat gaaccggcgg tgggcgcgaa gtcttctctc tggttgttga
    25981 aggtgacccg ctgtccgggc caggcaggtc cggatgaggg catcggcgcg ttctcgactg
    26041 tccacacggg acacatttcg tggccggggc ccccgattcg agcgcttctc gaccgggtca
    26101 cgaatgacga agagcgttcc attgtggggt gtgtggaaat agggacgttg agtgtcccta
    26161 ttcccacaca ccgctcgcgg cagggtcgtt ccaccgggcg accgccgacg tcgctaaccc
    26221 cccaccgaag cgaccgaaac agcacgggcg gcggccgtga aactcgccca gcccaccagt
    26281 tcgatcaact ctcgatcagt caggcccgcg gccgcgacca gcgcgtcgtc gacctgatac
    26341 ggcgccttcg cgaccaccaa ggccaaccgg accccgggat cgtcgaaggc gtccacccaa
    26401 gcccggctca gcccaggcgg cgaaccgtcc caagtggaca gttcccgctc cacgacctcc
    26461 cgaaccgccg aagacaccgg aagtgcggcg aacgccgagg aagcacggga gaacgcgtcg
    26521 acgatcaacg gattacccac cgcccaggcg aaatcccccg accccgaagg cagcaggtcc
    26581 agcgaatccc caggcggagc ctcttccacc gggcgaagga accgccccag aaccgctttc
    26641 gccttggcac gcgccgaatc cggcacggac gaaggcagcg gcgacgaccc gaggaagacg
    26701 ctcaccaccc gattcaggta gtggaacgcg aacgcgaccg cggtcagctc cgcacgggca
    26761 cccgtcgaca tggcccccgc acgaggatcc gccacgggcc gccccgaagc gatcgccgac
    26821 gcctccgatg aacgcccgag cgagtccagc gccatcccgt ggacctcgac acagtacgga
    26881 cacgagttct ctcgcgacac cagcgtcgcg acgacctccc ggtccgcccg gctcgtctcc
    26941 ccgttcgcca ccagcgactc ccgcagcatc acccagctcg ccgcgagcac cgccggcgac
    27001 ggcgaatgca gcgccaccgg cggggccagc atgccgaagt cgcgttccag ccgtcggtag
    27061 acgtcgcgca cgagcccggt cgcccggccg aacgggaccg gccggacgta ccggacttcg
    27121 cgcaaggccc gccgcagcgc caacctcacc agcgcaggcg ccatgatcag ctcccggcga
    27181 ccagcgacag cttgctgacg gcgcgccgcc cggtgatgga gccgtccggt gcgggagcgc
    27241 cgtaggtgac gtcgacgccg cgtgcctgga gcgcccgcac gatacccggc accgaacgct
    27301 cggccagcgc cgcgatcgtc atcgccgggt tcaccgtcag cgcgcccggc acggaggcgc
    27361 tgtcggtcac gaagatcccg gggtgctcgc ggagttcgtg gttcgggtgc agcgccgagg
    27421 tcttcgggtc gtcaccgatc cggcacgacg ccagcgggtg cacggtgtac gcgccgacga
    27481 cgtcgttggt ccacggcgac accttcgcca ggccgtcctt ctcgaggatc tccttgcact
    27541 ccgcgtcggc cagcgcccag ccgtgccggg tgttcggcgt cgggtcgtac ttcagcggac
    27601 cgcggccgag catctgctgc gagatgcggt aggcgttgcc ggtgggcggc ggcgcgccga
    27661 agacaccctc gttgtcgtcc tcggtcatca ggaagatggt cagccaggag gcccacttct
    27721 tgaggatctc cttcttctgc gccccgaacc aacgcggttc gtcgccgtcg ggcacctgcg
    27781 ccaggatcgt gccgagcccc ggcgggaagt acagctgctc cagcgagtac cgctcgtact
    27841 ccggcaggga accgtcgagc ttgtcccagt tcgcgacggt cgggcccttg ccgatgtggt
    27901 tggcctcgta gaccttcccg tcctcacggg acagtccgag cacctcgcgg acccgctcct
    27961 cgttgatgat cgcggtgttg agccgctcac cgttgcccga gaagtaccgg ccgaccccgt
    28021 gcggcatggt gcccagcgcc gcctcggagc gctgcaggat caccggggtc gcgccggcgc
    28081 ccgcggcgat gatgacgatc ttcgcgtcga tcgtcccgct gccggactgg agccggtagt
    28141 cctcgtcgtc cacgatgttg aagtgcactc ggtagtcgcc gtcgtcgatc cgctcgatcc
    28201 gctggacctc gtgcagcggg cggatcttcg cgccgtgcgc gagcgcggcg ggcaggtagt
    28261 tggtcagcag cgagcgtttc gcgtcgaacc ggcagcccgc catcatgaag ttgcagttca
    28321 cgcagcggtc gttgtccacc gcgaccggcg ccgggttggc cgtccggccg gagtggtcgc
    28381 agaacgccgc ccacagccca cccgcgtacg agacgtcgtt ccagtcctgt ttggacaccg
    28441 gaagcgattc cgagacgcgg tcgtaccaag gctccagcga atcccgcgtg atcgtcgacg
    28501 gccacatgcg gcggccgatg ctgccgtggc gctcgaacac gaacttcggg gcgcgcggca
    28561 tcgcggcgaa gtacaccacg ctgccaccgc cgacgcagtt ccctccgagc acgctcatcc
    28621 catcgccgac gacgaagtcg aaagcccggg tgtaggacga gccgagcaga tagtcgtgct
    28681 cgaagtcctt cgtctccagc cacggtccgc gttccagcac ggtgaccttc gccccgcccg
    28741 cggccaggtg gtaggcgggg atggagccac cgaacccgct gccgacgatg acgacgtcgg
    28801 tcttgtcgta ggcagtcatg cggggctccc ggaaggcgtc gtgtcagggt ggagccgcgc
    28861 cagctcgcgg cgataggaga acttcgggaa ccgccacagc ccgtcttcgt ccggcgcggt
    28921 gtaccccatc gccagcaggc cggggtgccc ctcggcgatg gcttcggcgg tgtgcttgtg
    28981 cgcggcgctg tcgaaggaca tgttgcagaa caaggcgagg ctcacccagc cgtccttctc
    29041 cggatgccct ggcgcggtca gcgaccgcac gagcgccgtc cggtcggcga aggacagcgc
    29101 gacgaacggc ggcagcgact cgtcgagggt gaggtcgtgc tccttggcgt agcccttcgc
    29161 gtgatcgttg agggactgcg ccagatacgg cagcccgacg gtcaccccgg tcgcgtcggt
    29221 gtgcagcagt tcgagcgcgc ccgccacgac cgcgcccggc ccctccgccg cgccggcgat
    29281 cgcgtgatcg ccggggaatc gcttctcccc cggcaggatc gtgtccgcgt aggcctccaa
    29341 agtggacacc ttgacctgtt cgtccgaatc cacggaacct acctcctgtt cctggtgtgc
    29401 acggtcatcg gcagcccgcc ccgcacccgg agcgacaaca tcgcttcggg caccacgtcg
    29461 tagccgggga gcttcctgag ttcgaggtcc cgcaggacca tcgtcagcac gaagacggcc
    29521 tccatcacgc cgaggctgtt gccgatgcag aaccgcggcc cggcgccgaa cgggatgtag
    29581 gcgtagcggg gccgtccgct cggccggtcc ggatcgaacc ggtccgggtc gaacttctcc
    29641 ggctccggcc agaactccgg atgccggtgc agcgtgtagg gcacgacgac gacgtcggat
    29701 ccggcgggga cgtgatagcc gccgatctcg tcgtcggcct gcgccacccg aggcagcagc
    29761 cacaccggcg gatacagccg catgacctct tccacgaccc gcgccgtgta cggcaaccgg
    29821 tgcaggtcgt cgtgtgtcgg cgactggtcg cccagtaccg cgtcggcctc ggcacgcagt
    29881 ttcgccgcga tctcgggatg ttcgtcgagc aggtggaacg cccagcccag cgtgctcgcc
    29941 gtcgtctcgt gcccggccag cagcagggtg atcagctcgt cccgcatctg ctcacgggtc
    30001 ccgtcggtcg cgatgaggcg cgagagcacg tcctcgccgt tctcgaccgg gttggccagc
    30061 cgctgctcga cgagttcgtc ggcgatccgg cggaggtcgg cccgtgattc ccggaaccgc
    30121 agttgcttct tcagcggggc ccactgcggg accatgctca gcgtcaccgc ttcgaacatc
    30181 gcctggtcct gcacggcttc gaacgaatgc cccagcgagg tgaagccgcc gaggtccgcg
    30241 tcgagcaggg tcttgccgag cacaccgagg gtcagcccgg tcatctcgtg caggatctcc
    30301 accggtcctt cggtgtcccg caagcgtttc acgagccctt cgacctcgtt cgcgacgacc
    30361 gaggcctgcc gcgcgatccg cttgggctgg aacaccggct ggatggtccg gcgctgcttc
    30421 ttccagacgt cgccgtcact ggtgagcagc ccgtcgccga gcgcccgcct cgcctcctgg
    30481 aggccgattc ccttgtggta gttggccgcg ttgtccgcga gcacgtgttt cgccagatcg
    30541 gggtggttca ccaggtacat cgtcttggga ccgatcgcga tccggacgac gtccccgtgt
    30601 gcctccgccg aatccgacat gagcgccagc cggtcggtga agagcttctt cagcagaccg
    30661 aaggtcgccc ggcgcggcgg gccgggcggc gcgagacgcg ccgcccggct ggtttccgca
    30721 ccggaggtca tgccgccacg gccccggttt ccgtctccgg cttctcggcc ggcttgggca
    30781 gggaggtgac ttcggccgac ttcgcctgct cggcctccca cttttcggtg gccttcttgg
    30841 agaagtgcag gccccacagg aacgcgccgc ggatgaggca gaccagcgcg gtggcgagga
    30901 acaggccgta cgccacgtgc acgaccatga agaacccgta cgccagcgcc acgcccgacc
    30961 cgaacaggac ctgcgacgcg ggcttcgacg gggtcgtgcc cgggtcggtg accatgtagt
    31021 tcgtgtagag cacgaacgcc accccggtca tcatcccgag cgcgccgggg atcgcggtgt
    31081 cgaacaccag cccgcggatg atcgcctgga gcgcgaaggt gatcagccag gcgccgatca
    31141 gccacatccg ctgcgtcagc atcgcgttga ggacggtgcc cgacacgatg atgatgccga
    31201 cgatcagcca gccgacccag gagtcgacct gctcggtgaa gtgatacggc ggcgcgatgc
    31261 tcgcccaggg gaacaccagc aggatgatcg tgatgccgaa gttcgacggg ttcatgtagt
    31321 gccgcaaccg gccgcgcacc ggggcctgca ggacccactt ggcgccgacg gcgacgacga
    31381 cgccgaacat catgaccagc acctggtcgt tgacgtaggt gagcatgttc agcgcgagac
    31441 cggtgatatg cgccgggaag aggaactcca cgagtccctt gaacccgttg ccgcggaagc
    31501 ggacgccccg cccttgggtc cgggcgccga tgatctccag caggatttcc gtggcgtagg
    31561 ccgtggccag cgcgatgaac ggataggtgt agggctgctc gaaaccgagc acggtgtagc
    31621 cgatgatgtt gaagacggtg atcgagatcg cgaaccggcg aagggccgtg atcgtcttgt
    31681 tgctcttcgg tgcggtgagt gtctgctcag ccatgacggt catttctcct tagcctgagc
    31741 gccgagctgg aaggtgtggc tgcccggggt cagctggact tcctgcgtgc ggatctgccc
    31801 ggtcaggtcg cgccactgca ggcagacctt caccggcccg gtgaccttgc cgagtccgat
    31861 ctggatctcg tggctgcgct tgccggagtg gccactgccg ccgtcgaccc ggtccatgta
    31921 cttcttgccg tcaggggtga tgacggtgac ctgcgcgccg atcgccgcgg tgcccgccgc
    31981 cttgagcggt ccgtccgccg aagccttgtc gtgcaccagc ttcaggttca ggtaggaccc
    32041 ggcgtcgggg ctgacgttgc ggtagaagat cggctgctcc cactggcggg ccactgcgaa
    32101 gtcgagcttg ccgtcgccgt cggcgtcgcc ggtggcgata ccgcgcgtgg gcaccgggac
    32161 cgcgagaccg aggcgcgggg ccaggtccgt gtagcggccg tcggggctct tggcccagaa
    32221 gtgcagggtg tggtcgccac cgacgtcgtc accggcgacc atgttcggcc agaaggacgg
    32281 atgcttcagc agttcgtcgt tcgaggtcgc cagttcctgc agctgcggcc agcggttgac
    32341 gtcgcccttg acgaacccgg tcgcctgcgt gatcaccgat tcgccgctgt tgttgtagtc
    32401 ggcgatcttg acgtcccagc cccagccgga ccacgcggtg cccgcctgtg cgctgcggtc
    32461 gacccacggc gcctcgccgc cctgcagacg gccgcgcaga tccgcggtgt ccttggcggt
    32521 gttcatgaac tggaagtggc tttcctcgat cccccaggac gtcgtgatgt tgctgacgta
    32581 caggtcgtag agaccgtcgt ggtcgaggtc ggcgaagtcg acgcccatgc ccttgaagga
    32641 gtcgttgccg agcaccttgg acttcgggtc gttgggcccg cggacgccct tcacctcggc
    32701 gaactcgacg tgaccggggc gggacttgtt gtacagcagg cggtcgtgcc cgaagtcgtt
    32761 gccgatgtag agctccggca ggttgtcccc gtcgacgtcg gtggcgctgg ccgccagcga
    32821 ccagccgccc tgggcgtcgg ccgggatggc ctggtcatcg cagacgaacg tggccgtcgg
    32881 cttggcgcct tgggtggcac cggtgaagcg gaagatgtac ttgccgccgg cgttgtcggc
    32941 gtgcgacatc gacttgttca tctcgacccc gccctggacg cggtcgtcca gcaccgcgct
    33001 gtcggggaag tagttgccga tgaagatgtc ctggtggccg tcgccgtcga agtcaccgac
    33061 cgaggcggcg ttggtgttcc acagtggacc ggcgtactcg ccgttcttgg agttgttgcc
    33121 cggcaccagt tcgaccggct cgtaggcctt cggctccagc ttcgtggcgc ccggcttcga
    33181 gaggaacagg atcggggtgc ggccccagta gtaggccagc aggtcgaccc ggccgtcctc
    33241 gttgtagtcc gcgggcacgc agcccatggg cgcgatgtac ttccccatcg gcagcggtgc
    33301 cgcgtcgagc gcgaacggcg cgtagcggtc gccgcccttg cccggcgtcg gggtgatgac
    33361 gacctggtcg ctgcgcgggt cgacgaagca caggtcgttc gcgagcttgt cgccgtcgag
    33421 gtcgttgacc gcgatcgcgg cgccgaccga cgagatccag gcccggatgt gctcgtaatc
    33481 cttgttcacc gtccggatcg actggctctt cgccgcttcc ggcaaggcga tcgtcagtgg
    33541 ttcgaacgcg tacttcgagg ccatcgtgtc ggcctcggcg gtcgagaccg tgggcagctg
    33601 cgccaccacg aacagacccg ccatcagcac caaggccacg atgcccgcaa gctgcttgcg
    33661 gagccagccc aaggtcgcgg tcatttccct gcacctccag agttgagaac ctcagcggcg
    33721 atgcgctgtc gccaggtttc gaatgccggg agttcgccgt cgaccacggt ggcggggcgc
    33781 acctcctggg tgatggccgc ggcccgctcg gccggcagcc cgcagatcgc ctgcgtggcg
    33841 acctcggtct cagggatcag cagcccggcg cggacgcggg cttcggcggc gaaagcgctg
    33901 ccctgggcga ggttcccgcg gtgctcaccg gcgaactcgg ccagtttcag cagttcgtcg
    33961 gaagtgaccc cgcacgcgta ggtcgaggcg agcccgaccc cggcgtagag gtctccgtgg
    34021 cgccgctccg ggaagcgcgc gatcgcgtcg gcgacgaggt cgacgtcggt accgcagatg
    34081 aaccacagcg cccgtccgat gccctggtcg atcgcccgca gcgcgtaccc gtcgttgccg
    34141 ggcggccagg agaagccagg gtcctggaac tgcccgtcga tgtacttcgc cgtcttgaag
    34201 tacgcctggt ggaagccgta gccatcgagc accagccagc gcagcaacgg atcgaagtcc
    34261 tcggcggagg gccagcggaa gcgcggcagc cgcgccatcg cccagccgac gccgacgtag
    34321 atgatgtagt cgtgcttctc accgggtccg gcgaggaact cctcgatgtg ccggcgtccg
    34381 cctcccggca gcccgtccag cattccgtat cccattcccg cgccttcgta ggcgaagccg
    34441 cggtatttca ccggaatacg ttcgagccat tcttccgcct ggtcgacgga acgcgcttcg
    34501 accgcgtgcg cgtagccgag caggaatttc tcaccgacgg tctccagcaa ttcttgagcg
    34561 gctgggctct tcttgtggaa accgcgcttg tccagtgacg tctcggagac gtccggtgtg
    34621 atcatgcgcc gtctgatcgt gcgccaacca ttgcccaacg cactctcccc ctatcgggtg
    34681 gattcgaatt ctggatcgct taaagcgtca catgcgtggt gatggcccag ctactccacg
    34741 gttgcgtccg cgttctcccg gtttgcgaga ccgggagaac gcggaacgac ttcggtcagg
    34801 ccaccgcgcg caggtacccg ggcgccggcg cgaccatccg gttccccgcc gacgtcgggc
    34861 caccggcgag ggtgatcgcc atcggcgcgt cggtcggcag cggggcgcgc atcggcatcc
    34921 ggaggtggac catgccgtac cgggtgatgt cgacgcgggc gggcagcgtg cccatggaga
    34981 acgaggacgc cgcggtcccg gcggcgtgtt cggccacgcc gatgacggtc caccggccct
    35041 cggggacgtt ctggatctcg atgtccgccg acaggacgtt cgccctgcca ccgaaggcga
    35101 ccgggccaca ctgcgggatc gactcggcga acagtccgat gaggacggtc gccgggccgg
    35161 ccccgcgcgg ggtctcgacc cgcacgctga tcgtgccggt cccggttcgc atcgtcgggc
    35221 tgcccattcc ggcactgtgc aacgcttcca gggtcggaag ccgctggaag tgcggggcca
    35281 tcgccacgag cagttcgccg acctcgggat cgcggtactg ggtcggggtc atcccgaccg
    35341 cacgggtgaa gcggctcgtg aacgtgccga cactgctgta gccgacgctg cacacgatgt
    35401 ccgacaccgt cagcgatgtc gtcagcagca gtcgtttcgc ttcgaagagc cggatcgcgg
    35461 tgaggtagcg gccgggggtg acaccggtcg ccttcgcgaa gatccgggag aaatggaacg
    35521 ggctgacgaa gacttcctgt gccagatcgc tcaaggtgat cgggtcgaaa tacctggcgt
    35581 gcatcgcgga gatggcctgc agcaccgcgg gttgcaaggg ggacgccggc tcagggtgcc
    35641 gaccgggttc ggtgacgcct ttctcgttcg ccgccatggc gactgttcgt agctgcatca
    35701 gaccaacctc ggattcgctg tcgcttttct ctgtacgcca gctaacgcgt cggtgatttc
    35761 agcgggctcg acgagcgatc gagatgggtc ctgcggtctt gtccgaacgt gcgctatcgg
    35821 tggacggtcg ggcccctggc acgcacgacc tcaagccggg aaatcgagca cgcattcccc
    35881 gacgccgacc tcggcgggcc agtcgagttt gagggcacgg tcgacgcggt cgccggcgtc
    35941 caccgggacg gcgtgcgcgg ccagtcccat ggcgcgggca acgaggtaga gcgtctgctg
    36001 caacgcaccg acatgcgcca gcgtcgtggc gtacgcgcca ccaccgagca cggacgccat
    36061 ccgcggcatc cgcgcggtga cggtgatcag cgccgagggc catcgatggt tgccgccacc
    36121 gatcatcgcg atgtcgagca tctcgtcgag gtcggccgcg tcatcgttga ccaggtcgag
    36181 ccgatggccg agcggatcgt agtggtagat cccgcggtcc agccccgaac agcggttcac
    36241 cgacacgtaa agctcgagtt cgtacaggca ggcgacactg aagtacggcc gttgcgaggc
    36301 gctgtgcgcg ggcccgttcg gaagatgtgc gggcccgatc gaccggatgc gcgcgccgcg
    36361 gtacaggaac tcgccgatct gctcggccga cagcacgctc tcggtgaact cggggcagct
    36421 gtggtcgtgc tccagcaacg ccgtcagcgt cggatcggtc tcggcgcgat cggccagatc
    36481 cggccggaac agcgagtagc tcgggccttc gccggtgggg gccttgacca ccggcggatt
    36541 cccgagcccg gcgaggtcgg ccgggccgcc cggccgccag gtccggctcg tggtgtggaa
    36601 cgacagctcg tccggggacc acacgcgcag ttcgggatcg tcgtcctcgg cgaacctgcc
    36661 gttctcggcg gcctggacga cgcccgcggc gaccagatag gacacgatcg cgccgaccac
    36721 gccgcgatcg atcccggtcg tggtcacgat ctccccgacc gacttcgccg tcgcgagggt
    36781 cgccgcgacg tgcaccgccc acggctggga cagcacgaca cggtagcgcg cggacggcga
    36841 ctccagcccc atcccgtcgg cgtcggaacg cagggaactg aagcgggaca accggatcgg
    36901 gcgggtggcg gggatctcca ccggcgcgaa caccggcgcg agcacgaccg ggatcaccga
    36961 cagcagcggg ccgcggccgt cggcgagccc gagcgagcgc accacggaac cgccgagttc
    37021 cttgagcacc tgccgcagcg cgtcggcgcc ctcggccgtc cagctcagtt cgccttcgag
    37081 gtcgggctcc cgttcgacgg gctcccacga agacgtcacg ttcgccagcg acaccggacc
    37141 caaggccatc cgccgcaacg attcccgcac cagaggttcc gcgtgcggga attcgtgctc
    37201 accccagcgc gtgacgacca ccagtgagcc gtcctcaccg atttcgacaa ggctgtcgtc
    37261 ggtgagcgac cacaggggga tcgtttcggc cacaccgccg gggtgatctg tcgtcaactg
    37321 ttgctccagc ttgatctaca agaacatggg gaacggattc agccgctcgt agggggtcgg
    37381 ttcggcgagc ctgcccagac gcaccggcac gtcgaacagc cgtccgggag cgaagcggct
    37441 ccagaacggg cgcagccccg gaacgaccac ccggaccacc gggaggtcga tgtcgggcct
    37501 cgtctggtcc agcaccagcg tctccattcc cagcacggaa agcctgcgta ccaagcactc
    37561 cacgtcgtcg cggacgtcgg gacgccggac gaacttgaag tccgcggccc gtttcgccga
    37621 ccggccgggc gccggcagca gatacggctg gttggcgacc gtcgcgtacc ggagccaccg
    37681 cgccgcgtcg ggatcgtcga gctcgacgtc gttcgcgagc accgccggga tcagctggtt
    37741 gagctcgctg accgcccgcc gcagcgccgt cctgggatcc aggtgggcgc cgaagcccat
    37801 catgacgttt tcgcgcggcc cgacgatact cctggacagc gcgaccatca ccggaacacc
    37861 gaggtccgcc gtcaggtcga ggacccacag ttcccggcct gcccgcgcgt actggccgac
    37921 catctcctcg gcccacgggt cgtcgaacga agcgatgtcg acgccgggca cgggaagccg
    37981 gttgtaccac cacagcgcga cggcgtcgcg ttcgacgagt tcgagcagcc cctgcaggat
    38041 cgcgtcctcg atactgcttc cggccgcgca gccgttggag tccgcgcgca tcccggtgag
    38101 cccgcattcc cacggcaccc cgtagtagag gtacgcggtc ggcatcagct tccggcgctg
    38161 ccgggagagc gaccacagcg gcgtccagtc gatcgcggct tcggcgtcga accgttccgg
    38221 gacgtactgg aagttggagt gggtggcgtt ccactcgacg cggctttcgt attggcgctc
    38281 gtcgaagagc atgcacgagt tcgggtggac ggcgtcctcg ccgagcgcgc ggtaggtgtc
    38341 gcggatccgc agttcgtcgc cctggtagtt cgccgagaac cgctcgatcg cctcgcacag
    38401 cgcgccgact tcggcgtcga tcgggctcgc gcccttgccg ccgttctccc cgcgcagccc
    38461 ggcctgcaac cccgcctcac cgcgcacgcg gcgcgcgacg ttcccgccgg agtggtacgc
    38521 gttcacgaac gcaggcgccc gtgggtcgcg ggagatctcc ttgacgatcc cggtgaccgg
    38581 gctgatcagg tgcccgtagc ggtcgagcac ctcgaccggg gtgcgggtcc ggtgcccgcc
    38641 accgccggac gtcgccttct tggcctcccg cagcaccacc ggttccgccg tccgcgcggc
    38701 gacgatccct tcgtcaccgc attcggggca ctggggacgg cgccgcagtt cgtgcaggcg
    38761 cccctgcagg tccaaggtgt ccaggatcca cacggcctgc tgccccggat agcggtgtcc
    38821 cgccagccat ttggacgctt cgagggagat cagatgggac gcggccgcgg tcagcggcgg
    38881 cacggccggc atcgggaacg aggcggggcc gtcgtgcccg agaacctcct ggacgcaggc
    38941 ctcggcgtgc cggtgccccc acaaccggtt cgtcaggcag tgccagcagc cggaccggcc
    39001 gggctgcatg atcgggccga tccacacctg cgaacccgac ggccgggcca acagccacgg
    39061 ccgcccggtg cgccggtgct cggcgtcgat ctccgccagg cgcgggtcga ggtagtcgtc
    39121 gcacagcacg atggccagtt cggacgccgt gtcgaccact tcgatcccgc tcgcggccag
    39181 cccgctcgcc acctgtgagg tgtcgatgcc actgccgatc gcggtcaggc tcgccgtcgc
    39241 cggcttctga cggccggcca ccgcggaggc gtcgaggccg cacgcgtccc agtacgcgag
    39301 cgcgcgttcg tccccgctga tctcgtccgg gacgtggacg gtgaccagac cggcctcgac
    39361 cagcctggcc agcacgccgg tgacctgttc ggcgctcatc ccgtccgggc gggcggacag
    39421 gagtccgtcg aggtcacggg tgccgtcgag cagcgccgcc accgacgcga cctgcgcgcc
    39481 gcgcatcgcg atgacccctt gttccgaaaa cagataggcc ccgttccccg cgcggacctc
    39541 cacgcgcaga tgccgtttga accccagacc accgctgatc gagccggacg tggacgatgc
    39601 ctcacgcatg tggaccccca gaaggtcggt tcgattctcg aatcctgctc ggccgccttt
    39661 gccccggcca gtgcgcgatt catgtgtcgg acatgaaaaa cccacgttct tccgggacac
    39721 acgcacgcgg aagctggtgg acggctcact ggcccgcgac gggccgctct gccactgtcg
    39781 aagtactggg aatcaggtct cgacgcgtat cgagctggag ggcgcttgcg atgtacaccg
    39841 gatcacgagt agcggacacg caccacggct cggcacccaa cccgattccg gtcacgcccg
    39901 caagccccgt ccgtttcacc ctcctcggcc cgctcgaact cgtgcgggac gggatcgact
    39961 acgcaccgac gacgccgaag ctgctccagg tgctcgccat gctggtgatg agcccgggca
    40021 agatcgtgcc catcgacacg atcgtgcggg aactgtgggc cgacgatccg ccgcgcagcg
    40081 tccgcaccac catgcacacc tacgtctacc agctgcgcaa atgcatcgag gagaacgagc
    40141 tcgccccgta cggtgagacc atgctggcga cgaaaccgcc ggggtacgtg ttccggatcg
    40201 cccccgagca ggtggacgtc ttcgagttcc aggagctgca gcagcggggc cgggaactgc
    40261 acctgcgcgg cgagcacgtc gaggcggcga aagccttccg ctccgcgctc gccctgtggt
    40321 cggggccgcc gctggcgaac gtccattgtg gaccggtgtt gtcggcgtac tcggtcgacc
    40381 tcgtcgaaca gcggcgcagc accctgcacc tgcggatcga ggcggacatc gcggccggga
    40441 tgcggcacga gctgatcggt gaactgcgtt ccctcgtcgc cgcgaatccg ctggacgagg
    40501 ccctgcacgg gcaactgatc cgcgtgctcg gccgcagcgg gcggcgttcc gacgcgctcg
    40561 ccacgtaccg tcaggtgcgg actcggctca actacgaact gggcgtcgag ccctgcgacg
    40621 aactgcaggt actgcaccac ggcctgctct ccgagggtga acccgcgtga acaccattcc
    40681 cggcacggaa acgaaagtga ggatcgacgg atgagcattc gtacctatgg acagttctgc
    40741 ggtctggcca gggcgctgga gatcatcggc gaacgctggt cgctgctgat cgtccgtgac
    40801 ctcgtcctcg gcccgaagcg gttcaccgag ctgcaggcgg gcctgcccaa gatcccgccg
    40861 agcaccctct ccgcgcggct caacgaactc gagcagtccg gggtgctccg ccgccgcctg
    40921 ctcccccagc tcgacgccgc cgtggtctac gaactcaccg agtacggcag cgaactcgac
    40981 cagatcgtgc tggacctcgg cctgtggggc gcccggtcgc tcgggcagcc gtccgccgag
    41041 gacgtcttca ccctggactc ggcgatcctc tcgctgtaca cgaccttccg gagcgaaaag
    41101 gccaagggcg tccaggtcac ctacgaactg cgctacccgg gcgagatgat cctgcacgcg
    41161 atcgtcgagg acggcgcgct caaggtcgcg gagggcgcgc atcccggcgc cgacgcggtc
    41221 atcgaaccgc tgggcccgtt catcaaggac ctgctgaccg gcgacctcac cgccgccgac
    41281 gcgacgcgaa ccggcaagat ccgcctcgaa ggcgccttcg aatacctcga actgttcgcg
    41341 gaattgttcc acatccccgc ggctccgaaa gtgaccgaag gaatcgtcgt ccgctgagcc
    41401 atccggcgta agaccgcagg tcggatcagc aatccggagt aacggaaacc gccgggtgac
    41461 gggatatcgt cgacatccgt caccggtcgg tctttcgtct taggagccct tcatggccac
    41521 acttgattcg cgtccgggtc tgctcgccgc gctcaacggg aaatatcacc gcgcggcgct
    41581 cctctccttc gcggtggtgg tcgtggccca ctgggccgaa cacctggtgc aggcgttcca
    41641 gatctatgcc ctcggctgga agaccccgga cgcgcgcggc gtgctcggga tccccttccc
    41701 gaagctgatc agctccgaat ggctgcacta cgggtacgcc atcgtcatgc tggtcttcct
    41761 gttcgccctg cgcaaaggtt tcgccggtcg ttcgcggcag tggtggaacc tcgcgctcgg
    41821 cctgcagttc tggcaccaca tcgaacatct gctcctgctg atccaggcgc agaccggctg
    41881 gcggctcggc ggcggcaccg cgccgagcag catcatccag ctgttcatcc cgcgtgtgga
    41941 actgcacctg ttctacaaca cgatcgtcac catcccgatg atcatcgcga tgctcgtgca
    42001 ccggaaggcc cccgccgtcg agcgggagct gaccgggtgc acgtgctcgc ccgaaagccg
    42061 gcgtgagctg gcgaccgcgg cgtcgtgacc aggaggctct tcgcgctact ggcggtgctg
    42121 gtggcgtggt tcggggtcgc ggtgctcacc gcggccccgg cctcggccca cgtcgagctc
    42181 ctttcttcga accccgccga cggcgcccgg ctcacgtccg cccctgcccg ggtctcgctc
    42241 accctgtcgg agaacatcgg catccagccg aattcgatca aggtcgtcga ccagcaaggc
    42301 accgacgtgg tggccggtcc ggtgttccag ccgggcgaga tcgccgaaga ggtcgccgtc
    42361 gcactcgaac ccgatcttcc ggacggcagc tatctcgtcg agtacgcctt cgtctcggcc
    42421 gactcgcatc cggtgcgcgg cacgatcgcg ttcgtgatcg gcaccggccc cctgatcacg
    42481 tcggcgggcg cggtgtccgc ctccaccggg accgatccgg tgaccgacgc gctgttcacc
    42541 accttccgct ggggctcctt cggcggtgtc gcactgctgg gcgggctggt gttcctgctg
    42601 gtctgccgcc ccgagggccg caccgatccg tcggcgcgga agctgatcac cgcgggtctg
    42661 tggctctcgg gggtcacggc cgtggcggga ttcctgctgc aaggtccgta cgtcacgggc
    42721 cgcggggtgg gcgcgctctt cgacccggcg ctgatcgagg cgaccctgcg ggtggcgtac
    42781 gggaagctcc tgctcctgcg cctggccgcg atcgtcgcgc tcgccgtgat cgtgcgacgg
    42841 ctgctcacgg gtgaccttcc ggagcggctg cgttcgcgct acgagaacct cggcatcgcg
    42901 gccgggttca tcgtgatgct gagcttctcc gcgaccgggc acgcggtggc cgacaagatc
    42961 atgttcctct cggtcagcgc cgacctggcg catttcggcg cgatggccgt gtgggtcggc
    43021 gggctgatcc agctggccgt gctcctgcgc ggcaggtact cggcgtccga ggccgagccg
    43081 gcgctggccc ggttccaccc gatcgccacc cggtcgatcg tgatcatggt ggtcagcggc
    43141 gcctacctgg gcttccggct cgtgccgtcg gtggaggcgc tctggacgtc ggcctacggc
    43201 atcgtcttcc tgctgaagct gaccggcttc gccgcgttgc tgtgggtggc gaacctcagc
    43261 cgcaacgccg tgcggcgcgg gatctccggg cgcggcggca ccggcgtggt gaccgccgac
    43321 ctgcggaaac tgcggatcag cgtcggggtc gaggtgctga ttgtcgccgt ggtgctcgcg
    43381 ctggccgcgg cgctgtcctc gatgtccccg accggctgat caccgctcga tctccgcttc
    43441 cggtggggcg aacggccccc aggtgaaagc ccggagccac ggctctggat cgccgagcca
    43501 ctccatggcg gcgatctggg ccgggctccg gcgcccggcg agcgatcggt aaagatccac
    43561 gggcgcgccc gagagcaccg cggcgaccgg ttcggtaccg gcgatccagg tcgcgccctc
    43621 ggtctcgatc cgcagcccgg ggagcccgtg cctgcccagc gagtcaccga ggccacggac
    43681 gagcacttcg aatcctcgca gccaggcggc gtgcgctccg ggcggcggag cgccgagcgc
    43741 gtaccggaga tcgagttcgt gggtgaaggc gtccatcacc aggatgtcgc cgcggccctt
    43801 cccctcgccg tcggcggcga ggagggcgtc ggcctcggga ccccgttcga gccagagctt
    43861 cagtacttcg gcggccgacg ccgtctccgg caccgggcag gcctcaccac cgaaccgggt
    43921 gatcacccgg tcgcagatct cggccagatg cgcgatcagc tcgcgcacgg tccactgtgg
    43981 acacgccggg acgacccgtt cggcggcgcc cgcgtgatcg gcgagcaaga tcgcgaagtt
    44041 ctctctgacc tgccgatacc cttcggccgc tgtcgccgta ttccagccag ggacccgaat
    44101 tcggctgctc gtcacgcggc cacctccagt aggggtaagc gatggtcgtc cattctccca
    44161 ccgccgcgga gcttcaccct tctccccgct tgcgcgtacc gttcaacgca aagaccaccc
    44221 acccgtggcg cgtgtcgccg cggcttcagg cacactggtc ggtgaaagcc ccgtgtggca
    44281 agagaaagcg cccaatggcg acacatcgac cactgtggag gtgaccaatg gagatgcccg
    44341 gcttcgatct ggcgtggcgt ggtttcgatc gcgcgcaggt ccgggaattc gttcgcgagg
    44401 tggaagccga actacgacga gtggaagccg aacgcgatga agcgctccgc cgtggagacg
    44461 cgctcgccgc cgagctcacg gccgcgcgtg aggacaatcg agaattgaag gccacggtcg
    44521 accggatcag ccgtgtgccg atcgcgccgg acgcgttgca ggagcgctcg cgccgcatgc
    44581 tcgaactcac ccgcgaggaa gccgaggaga tcaccgctcg cgccgccgaa gaagccgcca
    44641 aggccgaggc gcaacggaag cggatcgccg aagacttcga gctcgccatg acgctgcgcc
    44701 gcgcggaggc gatgcgcgcg cttgccgcac gggacgaagc cgcgcaggcc cgggcgcgaa
    44761 aactgctcga cgacgccgcc gaagaaagcg agcgtctggt cgccgaagcg cggcagaagg
    44821 ccgacgttgc cctccgcctt cgcgatgacg tgctgaaaca gctggtcggc tgccgcgaat
    44881 tgctcaccga ggccggcttg gtgctggccg tgcccgactc acctgaaccg gaagtgcccg
    44941 ttcagcgccg gagcaggccc gaagcccgca ccggcaccga agcggccgcg acctgactaa
    45001 gcggggtcac ccgaggaaaa gaccaccggc cggatctcca tcgcgttgat gtgcgcgtcc
    45061 gggatctggc ccgcgatctc gatcgcgcgc tccttgctgt cgcattcgac caggtagaag
    45121 ccggccaggt actccttcga ctccgcgaac gggccgtcgg tgaccaccgg gacgccgtca
    45181 cgcacccgca ccaccgtgct ctccttcggc tcccccagcg cctgcgtccc cagcagttcg
    45241 ccgctctcgg tgagcttctt catgaaaggg tcgatgcggg cgaccacctc gtcgcgctcc
    45301 tcctcgggaa gggcgtccca ggcggtgggg ttcatggtga tcatgatcat gtacttcatc
    45361 ggtgttcctc ctggtcgtcc ggccgatacc cggccactca cagaggagtc ggagccgccg
    45421 gatcgtcctc gacatcctgg catccggaaa ttcggccgcc cccggcacat acgtggggag
    45481 ggtatactcg tcggagacag ggaacgacga gagaacgggt gcggaatgac gggctacggc
    45541 accgagcggg aggcctatct caagcgcctg cgccggatcg aaggacagat ccgcggcttg
    45601 cagcggatgg tcgaggagga caagtactgc atcgacatcc tgacgcaggt gtccgcggcc
    45661 acgaaggcgc tgcagtcgtt ctccctcgaa ctgctggatg agcacctcgc cacctgcgtg
    45721 gtccacgcgg ccgccgcggg cggtgaagag gccgacctca aggtccggga ggcgtccgac
    45781 gccatcgccc ggctggtccg gtcctgaagc gtcgcagccg caggctgttg gtgacgacga
    45841 acaccgagga gaacgccatc gcggcccccg cgatcatggg gttgagcagg ccgagcgcgg
    45901 ccagcggcag cgcggcgacg ttgtaggcga acgcccagaa cagattgccc ttgatcgtgc
    45961 cgagcgtgcg gcgcgaaagc cggatggcgt ccgcggccgc gcgcaggtcg ccacgcacga
    46021 gggtcaggtc accggcctcg atcgcggcgt cggtgccggt ccccatcgag agaccgaggt
    46081 cggcctgcgc gagcgcggcc gcgtcgttga cgccgtcgcc gaccatggcg accacgcggc
    46141 cttcggcctg cagtcgcttg acgacgtcga ccttgtcggc gggcaggacc tccgcgatca
    46201 cctcgtcgat gcccacctcg gcggcgacgg ccttcgcgga accggtgttg tcgccggtca
    46261 gcaggaccgg gcggagcccg agcgctttca gttccgccac ggcctcggcc gacgtcggct
    46321 tgacggtgtc ggcgacgacg accacgccgc gcgtctcgcc gtcccaggcg acgacgaccg
    46381 cggtggcgcc acgatcctcg gcggccgtcc tgacctggga atactcttcg ccgacagcga
    46441 tgccgtgctg gtcgaggagg gcaggccgcc cggccaggac ggtcttgccc tcgaccacac
    46501 cgaagacacc cagcccctcg acagtgcgaa acccgtcgac cggcggcagt tcgccgagcc
    46561 gctcttcggc ggccgtgacg atcgcgcggg cgatcggatg ctcggaagcg tgctcgaccg
    46621 ccgcggccag ccgcagcacc tcggtctcgt cggcgccgaa aagatcggtg aggctcatct
    46681 tcccggcggt caccgtgccg gtcttgtcca ggacgacggt gtcgaccgcg cgagtggact
    46741 cgagtacttc gggtcccttg atgaggatgc ccagctgcgc gccgcgaccg gtgccgacca
    46801 gcagcgccgt cggcgtggcg aggccgagcg cgcacgggca ggcgatgatg aggaccgcga
    46861 cggcggcggt gaaggcggcg tcggctccgc tgccggctcc gagccagaag ccgagcgtgc
    46921 cgaccgcgag cgcgatcacc accgggacga acacggccga aacccggtcg gcgagccgtt
    46981 ggacccgcgc cttgccgttc tgcgcgtctt cgaccagccg tgccatctgc gcgagctgcg
    47041 tgtcggcgcc gatccgggtg gcgcggacga cgagccgccc accggcgttg accgtcccgc
    47101 cgacgacggt gtccccggcc cccacctcca ccgggaccgc ttcacccgtc agcatgctca
    47161 ggtcgacggc cgagcccccg tcggtcacga caccgtcggt ggcgatcttc tcgcccggcc
    47221 gcacgacgaa ctcgtcgccc gtcttcagcg ctccgatcgg gacgcggctc tcggcgccgt
    47281 ccttcagtag cgcgacatcc tttgccccga gttcgagcag cgcccgcagc gcggcgccgg
    47341 agcggcgctt ggaccgggcc tcgaagtacc ggcctgccag gaggaacgtc gtcaccccgg
    47401 cggcgacttc gaggtagagg tggcccgcac cggaaccgcg ctgcatcgtc agctcgaagc
    47461 cgtgccgcat gccgggtacc ccggcggtgc cgaacagcag ggcgtacagc gaccagaggg
    47521 tggcggcggc gacgccgagc gagatcaggg tgtccatggt ggcggcgcca tgccggaggt
    47581 tcgtccaggc cgggcggtgg aacggccacg cgccccaggt gacgaccggc gcggccaagg
    47641 ccagcgagac ccactgccag taggtgaact gccaggccgg gaccatcgcc agcacgatca
    47701 ccggcacggc gagcacggcc gaaacgacga gacgcgtccg aagcgcgccg gtctggtctt
    47761 cgtcctcgtc gggcttgggc ggctgggccg tgtagccggc ggactcgacg acgccgacga
    47821 ggtcttcgac cgaaagcgcg gcggggaagt cgacctgcgc cttctcggtg gcgtaattga
    47881 ccgtggcgga gacgccgtcg accttgttca gtttgcgttc gacccgcgcg gcgcaggacg
    47941 cgcaggtcat cccgccgatc gccagttcga cccgctggga tgtcccgagg ctcacggcgt
    48001 acctcccgga tggtgcccgt gatgctcgct ggtcggcgcg ggcgagggcg gcgcctcgtc
    48061 cagcggcccc acggcggacc cgatcgccca ggcgacggcg aacaccgcga ccagagccgc
    48121 ggcgaacgcc gacaccttga cggcggtgct cacgagacga gctggtaacc ggcctcggtg
    48181 acggccgcgt cgacggcctg gacgtccaag ggcgagtcgc tggtgacggt gaccttgccg
    48241 ctggcgacgt ccacgttcac ggcgctgacg cccgcgatcc cgctgacctc ctcggtgacg
    48301 gaggaggcgc agtgcccgca ggacatgccc ttgacggtgt aggtggtttc ggccatcggt
    48361 acgaactcct ctacaggaca ggtggagcga tcacttcctt tataccccgt gggggtaggg
    48421 gtgtgcacgg agggtacggg gacactgcgg aaatgaggaa gatctccgcc atcggcatcg
    48481 gcgccggcga cccggaccac ctgaccgtcc aggccgtccg gcggctgaac gagaccgatg
    48541 tgttcttcgt gctcgacaag ggttcggaga agcaggacct gacagcgctg cgccaggaga
    48601 tcctcgaccg gttcgtcgaa cggcccggct accgcgtcgt gcgggcaccg gaccccgaac
    48661 gcgaccgtac tccggacgac taccggaagg ccgtcgccga ctggcaccgg ctccggaccg
    48721 acgtctacga gaacatgatc gcttccctgg gccccgacga gcggggcgcg ttcctcgtat
    48781 ggggcgatcc cgcgctctac gactcgaccc tgacgctgct ggacgccgtg ctggccaggg
    48841 gcaccgtcga gttcgagtac gacgtcatcc ccggggtcag cagtgtggcc gcgctgaccg
    48901 cccggcaccg gaccacgatg aaccagatcg gccgcccggt acagatcacg accggccgcc
    48961 gcctcgaggc cggctggccc gcggacgtcg acgacgtctt cgtgatgctg gacgcgaact
    49021 gcaccttctc gcagttcgcc gacaccggcc tggagatcta ctggggcgcg tacctcggga
    49081 cacccgacga gctcctgctc tccggtcccc tgtccgccgg actcgccgcc gaaatccgct
    49141 ccgtccgcgc ctccgcgcgc tcacggaagg gctggatcat ggacatctac cacctacgac
    49201 gcccggcccg cccctaactc ccgcccggcc ctacctcact cgcggggccc tcactcacgt
    49261 gcccaccccc gtcacccgcg tgtccagcac cgtaactcgc gtgtccggcg ccgtatctcg
    49321 cgtgcttgag cgcgtatctc gcgtgtccag acgcgtaact cgcgtgctca accggacgac
    49381 tcgtgtgctt gggtggacga ctcgtgtgat cagagggacg gcacgcgtgc ttgggtggac
    49441 gacacggcgt acgtgccctc ggatcgccgt gtcgtccgtc tgatcacagg tgtcgtccgt
    49501 ctgatcacgc gagttacgtc tctgatcacg cgagttacgt tcctgagcac gggtgttacg
    49561 cgctcgatca cgggtgttac gtccctgatc acgggtgtgg cgggttttg
//
