LOCUS       NZ_CP024972            12836 bp    DNA     circular CON 18-AUG-2024
DEFINITION  Amycolatopsis sp. TNS106 chromosome, complete genome.
ACCESSION   NZ_CP024972
VERSION     NZ_CP024972.1
KEYWORDS    RefSeq.
SOURCE      Amycolatopsis sp. TNS106
  ORGANISM  Amycolatopsis sp. TNS106
            Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
            Pseudonocardiaceae; Amycolatopsis.
REFERENCE   1  (bases 1 to 8806031)
  AUTHORS   Liu,K. and Tao,M.
  TITLE     Discovery of new natural product by Amycolatopsis speibonae genome
            mining
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 8806031)
  AUTHORS   Liu,K. and Tao,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (21-NOV-2017) School of Life Sciences and Biotechnology,
            Shanghai Jiao Tong University, 1954 Huashan Road, Shanghai, Shanghai
            200030, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP Assembly v. 3
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 116.0x
            Sequencing Technology             :: Illumina HiSeq 4000; PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_019330265.1-RS_2024_08_18
            Annotation Date                   :: 08/18/2024 03:49:46
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,321
            CDSs (total)                      :: 8,231
            Genes (coding)                    :: 8,179
            CDSs (with protein)               :: 8,179
            Genes (RNA)                       :: 90
            rRNAs                             :: 4, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 75
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 35 of 52
            Pseudo Genes (internal stop)      :: 4 of 52
            Pseudo Genes (multiple problems)  :: 6 of 52
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 21:02:24
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2570743
            Orig. end                         :: 2583579
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP024972.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..12836
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="hydrogen-cyanide"
                     /region_number="14"
                     /rules="(Fer2_4 and cds(Pyr_redox_2 and Fer2_BFD) and DAO)"
                     /tool="antismash"
     cand_cluster    1..12836
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(Fer2_4 and cds(Pyr_redox_2 and Fer2_BFD)
                     and DAO)"
                     /kind="single"
                     /product="hydrogen-cyanide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..12836
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[5000:7836](-)"
                     /cutoff="5000"
                     /detection_rule="(Fer2_4 and cds(Pyr_redox_2 and Fer2_BFD)
                     and DAO)"
                     /neighbourhood="5000"
                     /product="hydrogen-cyanide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(5001..7836)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="(Fer2_4 and cds(Pyr_redox_2 and Fer2_BFD)
                     and DAO)"
                     /neighbourhood="5000"
                     /product="hydrogen-cyanide"
                     /protocluster_number="1"
     gene            349..1563
                     /locus_tag="CVV72_RS11590"
                     /old_locus_tag="CVV72_11510"
     CDS             349..1563
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Amidohydro_1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020636353.1"
                     /locus_tag="CVV72_RS11590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CVV72_11510"
                     /product="amidohydrolase family protein"
                     /protein_id="WP_219152439.1"
                     /sec_met_domain="Amidohydro_1 (E-value: 1.7e-46, bitscore:
                     157.9, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNGSLLLRNARLLDPVKGEYTEGDLRCADGRIVEIGDGLTAGDAR
                     TEDLRGAFVLPGLIDAHVHVTASTADLGSLPASSPSYVAAHSARTMSRMLDRGFTTVRD
                     ASGADYGLADAQAEGLFRGPRLLFCGRALSQTGGHGDSRTRGANASDDHPCCAGLGRVA
                     DGVDAVRAAARDELRKGAHHIKVMASGGVASPTDRIDSTQYSAEELRAIVEEAEAANRY
                     VAAHAYTARAVNRALELGVRSIEHGNLIDDRSVELFLRHDAYLVPTLVTYWALKEEGRE
                     HGLPESSWRKVDEVLGAGMAALEKAAGGGVKLVYGSDLLGGMHRHQNHEFRLRGEVQSA
                     LEVVRSATSTAADLLNLTGEIGTLAPGAHADLLVVDRDPLEDIGVLAEPEKFRHIVQGG
                     TVVSP"
     gene            complement(1625..2995)
                     /locus_tag="CVV72_RS11595"
                     /old_locus_tag="CVV72_11515"
     CDS             complement(1625..2995)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aldedh"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1017: aldehyde dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007029073.1"
                     /locus_tag="CVV72_RS11595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CVV72_11515"
                     /product="aldehyde dehydrogenase (NADP(+))"
                     /protein_id="WP_255632635.1"
                     /sec_met_domain="Aldedh (E-value: 9.2e-28, bitscore: 95.8,
                     seeds: 89, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKQIESAAEIAGAWAATDPKTRTAVLTGVADALDAAGPSLIEVAD
                     AETRLGTKRLTGELARTTFQLRLLAAESGSYYDVRIDRPDPSWPPGPRPELRRYRTAVG
                     PVLVFAASNFPFAFSVAGGDTASAWVAGCPVVVKAHPGHPELSRRTAAVVVEALGRWGA
                     LLSLVEGEAAGVEALRHPAIAASAFTGSVPGGLALARIAAERPVPIPFHGELGSVNPVI
                     VLPGAARSRAEELAAGYAGSLTLGNGQFCTNPGLVFVPSESPFVDRVAERLREVPAAPF
                     LNDRIASGFRTGAVRLAAIPGMREVVRGPGAHLLEVDLEDFVPEAAEECFGPLGVVVRY
                     SRLHDVLPVLAALPGQLTTTVHALPEEAPDVEALRPVLADRSGRILWGGWPTGVAVTAA
                     IQHGGPFPATTSPASTSVGTAAVDRFLRPVSYQDWPSHLLPEPLRDDNPWDVPQRIS"
     gene            complement(3091..4092)
                     /locus_tag="CVV72_RS11600"
                     /old_locus_tag="CVV72_11520"
     CDS             complement(3091..4092)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020646747.1"
                     /locus_tag="CVV72_RS11600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CVV72_11520"
                     /product="proline racemase family protein"
                     /protein_id="WP_219152440.1"
                     /transl_table=11
                     /translation="MRSIRSITAVDSHTEGMPTRVVTGGVGVIPGDTMAERRRYFMEHL
                     DHLRQFLMNEPRGHSAMSGAILQPPARPDADWGVVYIEVSGCLPMCGHGTIGVATVLVE
                     TGMVEVTEPKTVVRLDTPAGLVHAEVEVRDGRAVRVKLRNVASFLTERDAVVEVPGFGE
                     VRYDLAYGGNFYAILELSQVDIPFDRAEKDRILAAGLDIMAAINDQRPPKHPADPLIGG
                     CKHVQFLAPGSDARASRNAMAIHPGWFDRSPCGTGTSARMAQLHARGELPLHTPFENSS
                     FIGTTFTGELVAETTVGGVPAVVPEFSGRAWITGNATYLLDPDDPFPAGFVL"
     misc_feature    complement(4060..4074)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: strong, score: 20.76"
                     /tool="antismash"
     gene            complement(4093..5004)
                     /locus_tag="CVV72_RS11605"
                     /old_locus_tag="CVV72_11525"
     CDS             complement(4093..5004)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005153898.1"
                     /locus_tag="CVV72_RS11605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CVV72_11525"
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="WP_219152441.1"
                     /transl_table=11
                     /translation="MSTPDLCGVVVATALPYRADASAPAGLAVDYDAYAAHCRWLVDNG
                     CRGVGPNGSLGEYSSLTDEERRRVARTAIETVGEDGIVVVGVHGPGSHQAKYWAEVAAE
                     DGADGLLCLPPTMYRANRGEVLAHFEAVASVGLPVMVYNNPIDTKVDLTPALLAEIARI
                     DNVVAVKEFSGDVRRVLEIREQAPGLDVISGADDVVLESLLMGATGWFAGFPNVFPAES
                     VRLFDLARSGKLEEARALYEPLVAAFRWDSRTEFVQAIKLGMDLVGRYGGPCRPPRGPL
                     TGEHREQVTADMRRALASLGVA"
     gene            complement(5001..6362)
                     /locus_tag="CVV72_RS11610"
                     /old_locus_tag="CVV72_11530"
     CDS             complement(5001..6362)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hydrogen-cyanide: Fer2_BFD"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hydrogen-cyanide: Pyr_redox_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1176: alkyl hydroperoxide reductase subunit"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016333970.1"
                     /locus_tag="CVV72_RS11610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CVV72_11530"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_255632636.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 8.6e-32, bitscore:
                     109.4, seeds: 64, tool: rule-based-clusters)"
                     /sec_met_domain="Fer2_BFD (E-value: 1.2e-07, bitscore:
                     31.0, seeds: 211, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNVVIVGAGPAGLAAAEHALRAGAQVTVLDQAETPGGQFHRMLPE
                     AYAARRPERGRHGRAEFDRRRRVLSHPRCRWWPGSTVWAFDRAEKTVHVLRGQSDGKGR
                     RRLTLAPDALILATGAHDRTLPFPGWELPGVYTAGAAQALAKGERVAIGERVLVAGAGP
                     FLLPVAESLLGVGAEVVAVLEANPFSTVRKGWSSRPWRLAAHAGKTGELARYAATLARH
                     RVPYRLGRAVIEARGADRVREVVTARVRADWSIVPGTERTYEVDAVCVGHGFVPQPELA
                     VAAGCVLDDGFVRVDAAQRTTVDGVFAAGEITGIGGAVTAAAEGAVAGCAAAGGEPSRE
                     LIRARDRALTFAGRLATAHPIGAAWRSWLREDTIICRCEETTYGALTRAAEDPARPGSH
                     AVKLGTRAGLGPCQGRVCGPTVSELCGGTERHHRPIVQPIRLGELAARTEGDPE"
     gene            complement(6359..6667)
                     /locus_tag="CVV72_RS11615"
                     /old_locus_tag="CVV72_11535"
     CDS             complement(6359..6667)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hydrogen-cyanide: Fer2_4"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007029078.1"
                     /locus_tag="CVV72_RS11615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CVV72_11535"
                     /product="(2Fe-2S)-binding protein"
                     /protein_id="WP_219152443.1"
                     /sec_met_domain="Fer2_4 (E-value: 2.6e-24, bitscore: 84.0,
                     seeds: 114, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSGRLLPRDRDPVGRTDRPIRITVDGETLTGIAGQSVAGILLAAG
                     RVSWRTTRSGAPRGVFCGIGACFDCLLTVNGVPDVRACRRPAADGDEIHTQSREETA"
     gene            complement(6664..7836)
                     /locus_tag="CVV72_RS11620"
                     /old_locus_tag="CVV72_11540"
     CDS             complement(6664..7836)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hydrogen-cyanide: DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1103: FAD dependent oxidoreductase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007029079.1"
                     /locus_tag="CVV72_RS11620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CVV72_11540"
                     /product="FAD-binding oxidoreductase"
                     /protein_id="WP_219152444.1"
                     /sec_met_domain="DAO (E-value: 1.4e-64, bitscore: 217.8,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNRTRVVVLGAGIIGAACARELSRAGFDVVVVERGRPGGGTTSHG
                     EGNILVSDKGPGAELELAKLSIALWPQVVAEIADEDARAASVIEYDPKGGIVVATTDDG
                     ARTLAAFAASQTGVRAEPLSLEEAAEAEPALTREVTAAFHYPEDAQVQPAGAALALLGS
                     AVRHGARLRSDTEVVGATVHNGRITGVRVPGEVIEADVVVNAAGPWAGQVSERLGAPIA
                     VRPRRGEVLVTTPMPGVVRHKVYDADYVGAVGADSSALQTSAVVESTWGGTVLIGSSRR
                     RVDFDDAIRPDVLSAIAVKALRLFPALADAAIMRAYGGFRPYVDDHLPVLGEDPRLGNL
                     WHATGHEGAGIGLSVGTARLLRELLTGAETAMPVEEFTVDRPAVLAEVAA"
     gene            complement(7915..8514)
                     /locus_tag="CVV72_RS11625"
                     /old_locus_tag="CVV72_11545"
     CDS             complement(7915..8514)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1148: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016333967.1"
                     /locus_tag="CVV72_RS11625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CVV72_11545"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_219152445.1"
                     /transl_table=11
                     /translation="MEDETPSIRDMLAVNLRAARAARGISLSELSRRSGIGKATLSQLE
                     SGGGNPTIETVFSLSRVLEVAISDLLDHRAGGALTVVRGADVEVLSGEGVDLRPLRRIE
                     TGDGVFEVYDQVVRGDAPQRSQGHVGVEHTIVQTGSLLVEVAGRSVEVGPGDYVAFDAR
                     EPHCYTAPEGPVHSVLLLQYRADERLDGRPHPVLKG"
     misc_feature    complement(8741..8761)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 19.62"
                     /tool="antismash"
     gene            complement(8826..10241)
                     /locus_tag="CVV72_RS11630"
                     /old_locus_tag="CVV72_11550"
     CDS             complement(8826..10241)
                     /EC_number="3.4.-.-"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0004177 - aminopeptidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0070006 - metalloaminopeptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1172: methionine aminopeptidase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005153882.1"
                     /locus_tag="CVV72_RS11630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CVV72_11550"
                     /product="aminopeptidase P family protein"
                     /protein_id="WP_219152446.1"
                     /transl_table=11
                     /translation="MTGDRTRPDLRALLAAKGFRNWISDGWEPADDTVDVPPGTAEAAA
                     AHRGRLSAELPGQRIALAAGRAVVRSNDTFHGFRADSDFVWLTGCQREGAILVMTPAGD
                     SHHATLYVPRPAEAHEPDFVGDADTSPLWVGSAAGPAAYGRTLGIECRPLEDLPHGLRG
                     RNPSFLVGAGVDPALDAYGFGHSERLRTVLAELRRIKDDWEIGQLRAAVDATALGFADV
                     LAALPEAVRGGGERWLQGTFDRRARTEGTGPGYTSIVAAGPHAPILHWTRCDGQVTEDS
                     LLLLDAGVEVDSLYTADITRTFPVGGEFTVAQRDVYDLVHKAHVAALGEVRPGQDYGAF
                     QATALRVLAEGLHDWGLLPVSVDEALSPDGQQHRRYIVCGTGHFLGLDVHDCAAAHPST
                     YREGTLAEGMALAVEPGLYFHAGDRTVPPELRGLGVRIEDDLVVTGSGYDLLSGGFPAT
                     ADEITAWVQAARG"
     gene            10332..11318
                     /locus_tag="CVV72_RS11635"
                     /old_locus_tag="CVV72_11555"
     CDS             10332..11318
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007029083.1"
                     /locus_tag="CVV72_RS11635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CVV72_11555"
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_219152447.1"
                     /transl_table=11
                     /translation="MALEIRHLRAICAIAEAGSLSQAAAALGMSQPSLTSLLQRLERRI
                     GAPLFARSHTGVTPTPVGEQTLRRALTLLVEFDRFESDLLGALGDGPVRLGSSQMDCLP
                     TFVERLDDALPGLDVTVHVEPSSAVLAQALARATLDIAVIAMSDDQEVPLAKHLGHRVL
                     FSWVPVFIGLPAEHRLAGGFEVDLADLADEAWIGPPGPEDGSLTSLRAATHRAGFSPRI
                     RFECPNGGGRHLIAAGQAVQLVEPTAPELPGMVVRPLKGDPMRMRLVLAWRKERLTWDQ
                     AENVYRAVMTSYTRHAMASTPFRTWWERRRSSRSWDGLVDFFRVDGP"
     gene            11386..11592
                     /locus_tag="CVV72_RS11640"
                     /old_locus_tag="CVV72_11560"
     CDS             11386..11592
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007029084.1"
                     /locus_tag="CVV72_RS11640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CVV72_11560"
                     /product="hypothetical protein"
                     /protein_id="WP_219152448.1"
                     /transl_table=11
                     /translation="MMPQRVWLGLAVVYTCTAVVQLYLLASTGAVWAGTLTAVGFAAAL
                     LCLLAAWRSSKRERRDTREIDSP"
     gene            complement(11589..12146)
                     /locus_tag="CVV72_RS11645"
                     /old_locus_tag="CVV72_11565"
     CDS             complement(11589..12146)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1298: putative carboxymuconolactone decarboxylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005153875.1"
                     /locus_tag="CVV72_RS11645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CVV72_11565"
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="WP_219152449.1"
                     /transl_table=11
                     /translation="MARIAPLAPPYEADVEKALRTWMPPGVAQEPLALFRLLQLHPELA
                     SRMRVVGTGLLAHGELPALDREIVIARVTARCGCRYEWGVHAAVFAPMVGLKPEQLEAT
                     VTGDSRHPVWSERHGVLIRAVDELHDTATVSGETWAALAGHFPAPELLEFLVLAGWYRT
                     IATVANGAGLEEEPWAVPYPGR"
     gene            12218..12556
                     /locus_tag="CVV72_RS11650"
                     /old_locus_tag="CVV72_11570"
     CDS             12218..12556
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1167:
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016333961.1"
                     /locus_tag="CVV72_RS11650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CVV72_11570"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_219152450.1"
                     /transl_table=11
                     /translation="MPGEPIPRPGQPVRGSETGRPLMAALDLLGRRWTLRVIWELRQGD
                     LGFRELRRRCGHMSSSVLATRLGELTEARIVEAGGEGYRLTPLGEQLLDAVHPLEKWGL
                     AWEKALRE"
ORIGIN
        1 gcgggcactg cgccgggtgc acagcagcca tccggtcgag tacccggtcg gcggcgagaa
       61 gaccgtcgag gtggccgccg ggtggctgga gcggtgcatc accggccagg agccctattt
      121 cgggccggac agcgcggcgg tgcgggagat cttcaccgac cacgaactca tcgaccggct
      181 cggctgcggc gcggtgatca acgtgccggt ggtggacggc ggccgcacgc tcggcgtcct
      241 caacctcctc gacgccgaag gcagttacga cgaggattcc gtcacggcgg cccgttcact
      301 ggcaccgttg gcggccccgg ccctgcgcga actcctggag gagacccgat gaacggatcg
      361 ctgctgctgc gcaacgcccg tctgctcgac ccggtcaagg gcgagtacac cgagggagac
      421 ctccgctgcg ccgacggccg gatcgtcgag atcggcgacg ggctcaccgc gggcgacgca
      481 cggaccgagg acctgcgcgg cgcgttcgtg ctgcccggac tgatcgacgc ccacgtgcac
      541 gtcaccgcgt cgaccgcgga tctcgggtca ctgcccgcgt cgtcaccttc ctacgtggcc
      601 gcgcacagtg cccgcaccat gagccggatg ctggaccggg gcttcacgac ggtccgtgac
      661 gcctccggcg ccgactacgg cctcgccgac gcgcaggccg agggcttgtt ccgcggcccg
      721 cggctgctgt tctgcggacg cgcgctgagc cagaccggcg ggcacggcga cagccggacg
      781 cgcggcgcca acgccagcga cgatcacccg tgctgcgccg gtctcggccg ggtcgccgac
      841 ggggtcgacg cggtccgcgc cgcggcgcgc gacgaactgc gcaagggagc gcaccacatc
      901 aaggtgatgg cctccggtgg cgtcgcgtcc cccaccgatc ggatcgactc gacgcagtac
      961 tccgccgagg agttgcgcgc catcgtcgag gaggcggaag cggccaaccg ttacgtggcc
     1021 gcacacgcct acaccgcccg cgcggtgaac cgcgcgctgg aactgggcgt gcggtcgatc
     1081 gaacacggca acctgatcga cgaccgcagt gtcgaactgt tcctccggca cgacgcgtac
     1141 ctcgtgccca ccctggtcac gtactgggcg ctgaaggagg aagggcgcga gcacgggctg
     1201 ccggaatcca gctggcgcaa ggtcgacgag gtgctcggcg cgggcatggc cgcactcgaa
     1261 aaggccgccg gaggcggcgt gaaactcgtg tacggcagcg atctgctcgg cgggatgcac
     1321 cggcaccaga accacgagtt ccggctgcgc ggcgaggtcc agtccgcgct ggaggtggtc
     1381 cgctccgcga cgtcgacggc ggccgacctg ctgaacctga ccggcgagat cggcacgctg
     1441 gcgccgggcg cgcacgcgga cctgctcgtc gtcgaccggg atccgctgga ggacatcggc
     1501 gtcctggccg agccggagaa gttccggcac atcgtgcagg gcgggaccgt ggtctccccc
     1561 tgacgcaatt cgtcacctac ttgcgacgcc gtcctctcgc aagcaggtga cgaatcgcgc
     1621 ggggtcagga gatgcgctgc gggacgtccc acgggttgtc gtcccgcagc ggttccggca
     1681 gcaggtgcga cggccagtcc tgataggaca ccggccgcag gaaacggtcc accgccgcgg
     1741 tcccgaccga ggtcgacgcc ggtgacgtcg tcgccgggaa cggtccgccg tgctgtatcg
     1801 cggcggtcac cgcgaccccg gtcggccagc cgccccacag gatccgaccg ctgcggtcgg
     1861 ccagcaccgg gcgcagcgcc tcgacgtcgg gggcttcctc gggaagtgcg tgcacggtcg
     1921 tcgtgagctg gccgggcagg gcagccagca ccggcaggac atcgtgaaga cgcgagtacc
     1981 gcaccaccac gcccagcggg ccgaagcact cttcggcggc ttccggcacg aagtcctcca
     2041 ggtcgacttc gagcaggtgg gcgccgggtc cccggacgac ctcgcgcatg ccggggatcg
     2101 cggccagccg taccgcgccg gtccggaaac ccgacgcgat gcggtcgttc aagaacggcg
     2161 cggccgggac ctcgcgcaac cgttcggcga cgcgatccac gaacgggctt tccgacggca
     2221 cgaacaccag tccgggattc gtgcagaact ggccgttgcc cagcgtcagc gaaccggcgt
     2281 agcccgccgc cagttcctcc gcccgcgagc gtgccgcgcc gggcaggacg atcaccgggt
     2341 tgacgctgcc gagctcaccg tggaacggga tcgggaccgg ccgctcggcc gcgatccgcg
     2401 ccagcgcgag cccacccggc accgatccgg tgaacgcgga ggccgcgatc gccggatgac
     2461 gcaacgcctc cacgccggcg gcttctcctt cgacgaggct caggagcgcg ccccagcggc
     2521 cgagagcctc cacgacgaca gccgccgtcc tgcgggacaa ctccggatgt ccgggatggg
     2581 ccttgaccac caccgggcat ccggccaccc acgccgacgc ggtgtccccg cccgccacgc
     2641 tgaacgcgaa cgggaaattg ctcgcggcga acaccaggac cgggccgacc gcggtgcggt
     2701 accggcgcag ctccggccgg gggccgggcg gccaggacgg atcgggccgg tcgatccgga
     2761 cgtcgtagta cgagccgctt tcggccgcga gcagcctcag ctggaacgtc gtgcgggcca
     2821 gttcgccggt cagccgcttc gtccccagcc gggtctcggc gtcggcgacc tcgatcaggg
     2881 acggaccggc cgcgtccagc gcgtcggcca cgccggtgag caccgccgtg cgcgtcttcg
     2941 ggtcggtcgc ggcccaggcg ccggcgatct ccgccgcgct ctcgatctgc ttcatgcttc
     3001 cttcctctcc gagttccggg atccgatcag cgggtacacc aggccgaaca ccgtccggag
     3061 cgcgtcgcga aaggcctttc acggacccgt tcagaggacg aagcccgcgg ggaacgggtc
     3121 gtccgggtcg agcaggtagg tggcgttgcc ggtgatccag gcccgtccgg agaactccgg
     3181 caccacggcg gggacaccgc cgacggtggt ctcggcgacg agttcgccgg tgaacgtggt
     3241 gccgatgaac gagctgttct cgaagggcgt gtgcaacggc agctcgccgc gggcgtggag
     3301 ctgggccatc cgggccgaag tgccggtgcc gcagggcgac cggtcgaacc agcccggatg
     3361 gatcgccatc gcgttccgcg aagcccgggc atccgacccc ggagcgagga actggacgtg
     3421 tttgcagccg ccgatcagcg gatcggcggg atgcttcggc gggcgctgat cgttgatcgc
     3481 cgccatgatg tccagccccg cggcgaggat ccggtccttc tccgcccggt cgaacgggat
     3541 gtccacttgg gacagttcga ggatggcgta gaagtttcca ccgtaggcca ggtcgtaacg
     3601 cacctcgccg aagccgggca cctcgacgac ggcgtctcgc tcggtgagga aggacgcgac
     3661 gttgcgaagt ttgacgcgga ccgcgcggcc gtcccggacc tcgacctcgg cgtgcacgag
     3721 cccggccggg gtgtccaggc gtacgacggt cttcggttcg gtcacctcga ccatgccggt
     3781 ctccaccagc acggtcgcca cgccgatcgt gccgtgcccg cacatcggca ggcagccgga
     3841 cacctcgatg tacaccacgc cccagtcggc gtccggccgg gcgggcggct gcaggatcgc
     3901 gccgctcatc gccgaatggc cgcgcggctc gttcatcagg aactgccgca gatggtccag
     3961 gtgctccatg aagtaccggc ggcgttcggc catcgtgtca ccggggatga cgccgacccc
     4021 gccggtcacc acccgggtcg gcatgccctc ggtatgcgaa tcgacggcgg tgatcgaccg
     4081 gatcgaccgc acctacgcca cccccagcga ggcgagcgcg cggcgcatgt cggcggtgac
     4141 ctgctcgcgg tgttccccgg tcagcggccc ccgcggcgga cggcacggcc cgccgtagcg
     4201 gccgacgagg tccatcccga gtttgatcgc ctggacgaac tcggtgcgcg agtcccagcg
     4261 gaaagcggcc accagcggct cgtagagcgc cctggcctct tcgagtttcc cggaccgcgc
     4321 caggtcgaac aggcgcaccg actcggcggg gaacacgttg gggaacccgg cgaaccagcc
     4381 tgtcgcgccc atcagcaggc tttccagcac gacgtcgtcg gcgccgctga tcacgtccag
     4441 ccccggcgcc tgttcgcgga tctccagcac ccgccggacg tcgccggaga actccttgac
     4501 cgcgaccacg ttgtcgatcc gcgcgatctc ggcgagcagg gcgggcgtga ggtcgacctt
     4561 ggtgtcgatg gggttgttgt agaccatcac cggcagcccg accgacgcca ccgcttcgaa
     4621 atgggcgagc acctcgccgc ggttcgcccg gtacatcgtg ggtggcaggc acagcaggcc
     4681 atccgcgccg tcctcggcgg cgacctcggc ccagtacttg gcctggtgcg atccggggcc
     4741 gtgcacgccg acgacgacga tcccgtcctc accgacggtt tcgatcgcgg tgcgggcgac
     4801 gcgacggcgt tcctcgtcgg tcagcgacga gtattcgccg agcgagccgt tcgggccgac
     4861 gccccggcaa ccgttgtcga ccagccaccg gcagtgcgcg gcgtaggcgt cgtagtccac
     4921 ggccagcccg gcgggggccg aagcgtccgc ccggtacggg agggcggtcg cgacgacgac
     4981 gccacagagg tcgggggtgc tcattcaggg tctccttcgg ttcgggcggc gagttcgccc
     5041 agccggatcg gctggacgat cgggcggtgg tgccgttcgg tgccaccgca gagttcggac
     5101 acggtcggcc cgcagacgcg gccctggcac gggccgaggc cggcccgggt gccgagtttc
     5161 accgcgtgcg agccgggacg ggccgggtcc tcggccgcac gcgtcaaggc gccgtacgtg
     5221 gtttcctcgc agcggcagat gatcgtgtct tcgcgcagcc agcttcgcca ggccgcaccg
     5281 atcggatggg ccgtggcgag gcgtccggcg aaggtgagag cacggtctcg agcgcggatc
     5341 agctcccgtg acggctcgcc cccggcggcg gcgcatccgg ccaccgctcc ctcggccgcg
     5401 gcggtgaccg cgccgcctat cccggtgatc tctcccgcgg cgaagacacc gtccactgtg
     5461 gtccgttgcg cggcgtcgac ccggacgaaa ccgtcgtcca ggacgcagcc cgcggcgacc
     5521 gcgagttccg gctgtgggac gaagccgtgc ccgacgcaga ccgcgtcgac ctcgtacgtc
     5581 cgctcggtgc cggggacgat cgaccagtcg gcgcggaccc gcgcggtcac gacctcgcgg
     5641 acgcggtccg ccccgcgagc ctcgatcacg gcccgtccca gccggtacgg gacccggtgc
     5701 cgggccagcg tcgcggcgta tcgagccagt tcaccggtct tcccggcgtg ggcggccagg
     5761 cgccacggcc gggacgacca tcctttccgg acggtcgaga acgggttcgc ctccaggacc
     5821 gcgaccacct cggccccgac gcccagcaac gattccgcga ccggcaacag gaacggcccg
     5881 gccccggcga cgaggacccg ttcgccgatc gcgacccgtt cccccttcgc cagcgcctgg
     5941 gccgcgcccg cggtgtacac gccgggcagc tcccagccgg ggaacggcag cgtgcggtcg
     6001 tgcgcgccgg tcgccaggat cagcgcgtcc ggggcgaggg tcagccgccg acgtcccttt
     6061 ccgtcggact gcccgcgcag gacgtgcacc gtcttctccg cgcggtcgaa cgcccacacg
     6121 gtggagccgg gccaccatcg gcaccgcgga tgcgagagca cccggcgccg ccggtcgaac
     6181 tccgcccggc cgtgccggcc ccgctccggg cgccgcgccg cgtacgcctc ggggagcatc
     6241 cggtggaact ggccgccggg ggtctccgcc tggtccagca ccgtgacctg cgcaccggcc
     6301 cgcaacgcgt gctcggccgc cgcgagcccg gcgggcccgg caccgacgat caccacgttc
     6361 acgccgtctc ctcccgggac tgcgtgtgga tctcgtcccc gtcggcggcc gggcggcggc
     6421 acgcgcggac atcgggcacg ccgttgaccg tgagcaggca gtcgaagcac gcgccgatac
     6481 cgcagaacac gccgcggggt gcgccggaac gcgtggtgcg ccaggagacc cggcccgcgg
     6541 cgagcaggat tcccgccacg ctctgcccgg cgatcccggt cagggtctcg ccgtcgacgg
     6601 tgatccggat cggccggtcg gtgcggccca ccggatcgcg atcgcgcggc agcagccgtc
     6661 cgctcatgcg gccacctccg ccagaacggc cggacggtcc acagtgaact cttcgaccgg
     6721 catcgcggtc tccgccccgg tgagcagttc ccgcagcaac cgagcggtgc cgacgctcag
     6781 gccgatcccg gcgccctcgt gcccggtggc gtgccagaga ttccccagcc gcggatcctc
     6841 tccgagcacc gggaggtgat catcgacgta gggccggaag ccgccgtatg cgcgcatgat
     6901 cgcggcgtcg gcgagcgccg ggaacagccg cagtgccttg actgcgatgg cgctcagcac
     6961 gtcggggcgg atcgcgtcgt cgaaatccac ccggcggcgt gacgagccga tcagcacggt
     7021 gccaccccag gtcgactcga cgacggcgga ggtctgcagc gcactcgaat cggcgccgac
     7081 cgcaccgacg taatcggcgt cgtagacctt gtgccgcacg acaccgggca tcggggtggt
     7141 caccagcacc tcgcctcggc gggggcggac cgcgatcggg gcgccgagac gctccgacac
     7201 ctgaccggcc caggggcccg cggcgttcac gacgacgtcg gcctcgatga cctcgccggg
     7261 cacgcggacg ccggtgatcc gtccgttgtg gacggtcgcg ccgacgacct cggtatcgga
     7321 gcgcaaccgc gcgccgtgcc gcaccgcgga gcccagcagg gccagggccg cgcccgcggg
     7381 ctggacctgc gcgtcctccg ggtagtggaa cgccgcggtc acctcgcggg tcagcgcggg
     7441 ctccgcttcg gcggcttcct ccagggacaa cggttccgcg cggacaccgg tctgcgacgc
     7501 ggcgaacgcg gcgagggtgc gcgctccgtc gtccgtggtg gcgacgacga tgccgccctt
     7561 ggggtcgtat tcgatcaccg aagcggcgcg cgcgtcctcg tcggcgatct cggcgaccac
     7621 ctgtggccac aacgcgatcg aaagcttcgc gagttcgagt tccgcgccgg gccccttgtc
     7681 ggagacgagg atgttgccct caccgtgcga cgtggttccc ccgccgggac ggccgcgctc
     7741 cacgaccacg acgtcgaagc ccgcccggct cagctcacga gcgcacgcgg cgccgatgat
     7801 gcccgcgccg agaacgacca cgcgcgttcg gttcatcgac cctccagcgt tcggtaaagc
     7861 gaacgatcgg agcgtaggtt ccaccctgga ggggtgtcaa cacctcgggc gcggtcagcc
     7921 cttcagcacc ggatgcggcc tgccgtcgag ccgctcgtcg gcgcggtact gcaacaggag
     7981 gaccgagtgc accggcccct ccggcgcggt gtagcaatgc ggctcacggg cgtcgaaggc
     8041 gacgtaatcc cccgggccga cctcgacgct gcggcccgcc acctcgacca gcaacgatcc
     8101 ggtctgcacg atggtgtgct caaccccgac atgcccttgc gaacgctgtg gcgcgtcccc
     8161 gcgcaccacc tggtcgtaca cctcgaagac gccgtcgccg gtctcgatcc gccgcagcgg
     8221 ccggagatcc actccctcgc cgctgagcac ctcgacgtcg gcgccgcgca ccacggtgag
     8281 cgcaccgccc gcccggtggt ccagcaggtc cgagatcgcc acctccagca ccctggacag
     8341 gctgaacaca gtctcgatgg tcggattgcc gccgccggac tccagttgcg acagcgtcgc
     8401 cttgccgatg cccgaccgcc gcgaaagctc cgacagcgag atacccctcg ccgccctggc
     8461 cgcgcgcagg ttgaccgcca gcatgtcccg gatcgagggc gtctcgtcct ccaccgcttc
     8521 tcccctgtcg ttcgtcaaac cgtacgacct cgttcgcttt gccgatcgag ttcgcggaca
     8581 tcatgacacg cctcacgacg cgtttcgagg ggatgacggt cattgagggg taaggcgaac
     8641 gtgtcgtggc gcgaagccga tcacacaccg attgtccaca aaggatgctc gcccggttct
     8701 gtgtccggtt cgggagccat gtgcggtggg tcgtgagtgg taatggtcgt tctaacgctc
     8761 tttatcactc acgaccccac caccaaaagg cgcgaacacc ccctgcctta ctcctcgtcc
     8821 gtccttcagc ccctggctgc ctggacccag gcggtgatct cgtcggcggt ggcggggaaa
     8881 ccgccggaca gcaggtcgta cccggacccg gtgaccacga ggtcgtcctc gatccgcacg
     8941 ccgaggccgc gcagctccgg cggcacggtg cggtcgccgg cgtggaagta caggccgggc
     9001 tccaccgcca gcgccatccc ctcggcgagc gtgccctcgc ggtacgtgga cggatgggcg
     9061 gcggcgcagt cgtggacgtc cagcccgagg aaatggccgg taccgcagac gatgtaccgc
     9121 cgatgctgct gcccgtccgg cgacagcgct tcgtccaccg acaccgggag caggccccaa
     9181 tcgtgcaacc cctccgcgag cacgcgcagc gccgtcgcct ggaacgcgcc gtagtcctgg
     9241 ccgggacgga cctcgcccag cgccgcgacg tgtgccttgt gcacgaggtc gtagacgtcg
     9301 cgctgcgcca cggtgaactc tccgccgacc gggaaggtcc gcgtgatgtc ggccgtgtac
     9361 aaggaatcca cttcgacgcc ggcgtccagc agcaggagac tgtcctcggt cacctgcccg
     9421 tcgcagcgcg tccagtgcag gatcggcgcg tgcggcccgg ccgccacgat ggaggtgtag
     9481 ccggggccgg ttccctcggt gcgggcacgg cggtcgaagg tgccctgaag ccagcgttcc
     9541 ccgccaccgc ggaccgcctc gggaagcgcg gccagcacgt cggcgaaccc gagggcggtg
     9601 gcgtcgacgg cggcacgcaa ctggccgatc tcccagtcgt ccttgatccg gcggagttcc
     9661 gcgaggaccg tccggagccg ttcgctgtgg ccgaagccgt acgcgtcgag cgccggatcg
     9721 accccggcgc cgaccaggaa gctcggattc cgcccgcgca agccatgcgg gaggtcctcc
     9781 agcggacggc actcgatgcc gagcgtgcgc ccgtacgcgg ccggtccggc ggcggagccg
     9841 acccacagcg ggctggtgtc ggcgtcgccc acgaagtcgg gctcgtgcgc ctcggccggt
     9901 cgcgggacgt acagcgtcgc gtggtgactg tcccccgccg gggtcatcac gaggatcgcg
     9961 ccctcccgct ggcatccggt cagccagacg aagtcgctgt ccgcgcggaa gccgtggaag
    10021 gtgtcgttcg accgcaccac cgcccggccc gcggcgagcg cgatccgctg accgggaagt
    10081 tccgccgaga gcctgccgcg atgcgcggcc gccgcctcgg cggtgccggg cggcacgtcg
    10141 acggtgtcgt cggcgggctc ccagccgtcg ctgatccagt tccggaatcc cttggcggcc
    10201 agcagcgcgc gcagatccgg ccgggttcgg tcgccggtca tcggctcccc tttcaggtag
    10261 tcacggttct ggccgcacct tcgcaccgcg aacggccggg ccgtaatgac cggcggcgat
    10321 agactccgcc tatggccctg gagatccggc acctgcgggc gatctgcgcc atcgccgaag
    10381 cgggcagcct ctcgcaggcg gccgccgcgc tcggcatgtc ccagccgtcg ctgacctcgc
    10441 tgctccagcg gctcgaacgg cggatcggcg cgccgctgtt cgcccgcagc cacaccggcg
    10501 tgaccccgac cccggtcggc gagcagacgc tgcgccgggc gctgaccctg ctcgtggagt
    10561 tcgaccggtt cgaaagcgat ctcctcggcg cgctcggcga cggcccggtg cggctcggat
    10621 cgtcccaaat ggactgtctg cccaccttcg tcgaacggct ggacgacgcg ctgccggggc
    10681 tggacgtgac cgtccacgtg gagccctcca gcgcggtgct cgcgcaggcg ctggcacgcg
    10741 cgaccctcga catcgccgtc atcgccatgt cggacgacca ggaggtgccg ctggcgaagc
    10801 atctcgggca ccgggtgctg ttctcgtggg tgcccgtgtt catcggcctc cccgccgaac
    10861 accggctcgc cggcgggttc gaggtcgacc tcgccgatct cgccgacgaa gcgtggatcg
    10921 gcccgcccgg ccccgaggac ggctcgctga cgtctctgcg cgcggcgacg caccgcgccg
    10981 ggttctcccc gcggatccgg ttcgaatgcc ccaacggcgg cgggcggcac ctgatcgccg
    11041 ccgggcaggc ggtgcagctc gtcgaaccca ccgcgcccga actgcccgga atggtcgtcc
    11101 ggccgctgaa gggcgacccc atgcggatgc ggctcgtgct ggcctggcgc aaggaacgac
    11161 tgacctggga ccaggcggaa aacgtgtacc gcgccgtgat gacgtcgtac acgcggcacg
    11221 cgatggcgtc gacgccgttc cggacgtggt gggagcggcg gcggagttct cggtcgtggg
    11281 acgggctggt ggacttcttc cgcgtggacg gtccatgagc gcgtggctgt aacccgatcc
    11341 cgcctcgccg cgattgaccc cgtaccgagc gaacggagac gggggatgat gccgcaacgg
    11401 gtgtggctgg gtctggcggt cgtctacacg tgcacggccg tggtccagct ttatcttctc
    11461 gccagcaccg gcgccgtctg ggccgggaca ctcaccgcgg tcggcttcgc ggcggcactc
    11521 ctgtgccttc tcgccgcctg gcggtcctcg aagcgagaac ggcgcgacac aagggaaatc
    11581 gactcaccct aacggccggg atacgggacg gcccacggct cctcttcgag accggcaccg
    11641 ttggcgacgg tggcgatcgt ccggtaccag cccgccagca cgaggaactc caggagttcc
    11701 ggcgccggaa agtgcccggc gagcgcggcc cacgtctcgc ccgaaaccgt tgccgtgtcg
    11761 tggagttcgt cgacggcacg gatgagcacg ccgtgccgct ccgaccagac gggatgccgg
    11821 gagtcgccgg tcacagtcgc ttcgagctgt tccggcttca agccgaccat cggcgcgaaa
    11881 accgcggcgt ggacacccca ttcgtagcgg catccgcagc gagcggtaac ccgcgcgatc
    11941 acgatttccc ggtccagcgc gggcaattcg ccgtgcgcga gcagtccggt gcccactacg
    12001 cgcatccgcg aagccagctc aggatgcagc tgcagcaagc ggaacagcgc cagcggttcc
    12061 tgtgcgacac ccggcggcat ccaggtgcga agggcctttt cgacgtcagc ctcgtacggc
    12121 ggggcgagcg gcgcgatccg ggccatgaac acctccagtg cttcgatttc agaaccacta
    12181 tgctgcttcg aaagtcgaag cacaaggggg tggtggcatg cccggcgaac cgatcccgag
    12241 gcccggacag ccggtccgcg gctccgaaac cggccgtccg ctcatggccg cgctcgatct
    12301 gctgggccgc cgatggacgc ttcgcgtgat ctgggaactg cgccaaggcg acctcggctt
    12361 tcgcgagctg aggcgccgtt gcggacacat gtcctcgagc gtgctcgcca cccgcctcgg
    12421 cgagctcacc gaagcccgta tcgtcgaggc cggcggggaa ggttaccgtc tgacaccttt
    12481 gggcgaacaa ctcctcgacg cggtgcaccc actcgaaaaa tggggtctcg cctgggaaaa
    12541 ggcacttcgc gagtgaccat gcgccgcgat gtatcccgcc gttcaccgca tctggccttg
    12601 ccacctgcgg tgagcagcgt acggtgagac gtacgtgagg ttgagtccac cagcccgcgc
    12661 gaacgacccg catgtccgcg gcccgagcac cttgtcacag ggcgacgcgg aggcgagttg
    12721 acttgcgcag ccgttgtgca ggcttacccg ttgtccgtct cgtcccggct atccgggaga
    12781 cagcaccatg accgaacgta ttcctttcac gcgaggcagc cgcgacggcc ccgcct
//
