LOCUS       NZ_CP024972            34065 bp    DNA     circular CON 18-AUG-2024
DEFINITION  Amycolatopsis sp. TNS106 chromosome, complete genome.
ACCESSION   NZ_CP024972
VERSION     NZ_CP024972.1
KEYWORDS    RefSeq.
SOURCE      Amycolatopsis sp. TNS106
  ORGANISM  Amycolatopsis sp. TNS106
            Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
            Pseudonocardiaceae; Amycolatopsis.
REFERENCE   1  (bases 1 to 8806031)
  AUTHORS   Liu,K. and Tao,M.
  TITLE     Discovery of new natural product by Amycolatopsis speibonae genome
            mining
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 8806031)
  AUTHORS   Liu,K. and Tao,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (21-NOV-2017) School of Life Sciences and Biotechnology,
            Shanghai Jiao Tong University, 1954 Huashan Road, Shanghai, Shanghai
            200030, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP Assembly v. 3
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 116.0x
            Sequencing Technology             :: Illumina HiSeq 4000; PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_019330265.1-RS_2024_08_18
            Annotation Date                   :: 08/18/2024 03:49:46
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,321
            CDSs (total)                      :: 8,231
            Genes (coding)                    :: 8,179
            CDSs (with protein)               :: 8,179
            Genes (RNA)                       :: 90
            rRNAs                             :: 4, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 75
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 35 of 52
            Pseudo Genes (internal stop)      :: 4 of 52
            Pseudo Genes (multiple problems)  :: 6 of 52
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 21:02:24
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1995203
            Orig. end                         :: 2029268
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP024972.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..34065
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="NAPAA"
                     /region_number="11"
                     /rules="(AMP-binding and TIGR02353)"
                     /tool="antismash"
     cand_cluster    1..34065
                     /SMILES="NC([*])C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(AMP-binding and TIGR02353)"
                     /kind="single"
                     /product="NAPAA"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..34065
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="False"
                     /core_location="[15000:19065](-)"
                     /cutoff="5000"
                     /detection_rule="(AMP-binding and TIGR02353)"
                     /neighbourhood="15000"
                     /product="NAPAA"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(15001..19065)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="(AMP-binding and TIGR02353)"
                     /neighbourhood="15000"
                     /product="NAPAA"
                     /protocluster_number="1"
     misc_feature    673..692
                     /note="TFBS match to DosR, Hypoxia stress response
                     regulator, confidence: weak, score: 23.12"
                     /tool="antismash"
     gene            complement(1390..2352)
                     /locus_tag="CVV72_RS08870"
                     /old_locus_tag="CVV72_08835"
     CDS             complement(1390..2352)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020662312.1"
                     /locus_tag="CVV72_RS08870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CVV72_08835"
                     /product="xanthine dehydrogenase family protein subunit M"
                     /protein_id="WP_219151943.1"
                     /transl_table=11
                     /translation="MRPFELLAPETVEDAVGSSGTFLAGGTTLVDLMKLNVLTPQQVLD
                     INAVPLRGIDTTDGLRFGALERMADIAGHPRVYPAISRALLLSASQQIRNMASIGGNLM
                     QRTRCSYFRDVAMPCNRRVPGSGCPAISGANRMHAVLGTSDSCVATHASDVAVALVALD
                     ARLRLVSEAGSRTVELGSFYRPPGDTPEVENDLRPGELIAEVVVPRLDWASNSTYVKVR
                     DRQSYEFALCSAAVALRVEGSRVVDARVAAGGVATVPWRLPAVEEALRGAPATVAAFED
                     AAALAAEGARPLAANGFKPSLLRRTIVRALLELTEGSRS"
     gene            complement(2339..2791)
                     /locus_tag="CVV72_RS08875"
                     /old_locus_tag="CVV72_08840"
     CDS             complement(2339..2791)
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /GO_function="GO:0051537 - 2 iron, 2 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020418979.1"
                     /locus_tag="CVV72_RS08875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CVV72_08840"
                     /product="(2Fe-2S)-binding protein"
                     /protein_id="WP_219151944.1"
                     /transl_table=11
                     /translation="MDISLEVNGRTEHLGVDPGVTLLDALRERLAVTGPKKGCDRGQCG
                     ACTVHVGGRPVLSCLTLAATVKQPVTTVEALSTEDGLHPVQQAFVDRDALQCGFCTSGQ
                     IMSAVAAIEQGVEDVREFMSGNLCRCAAYPNIVAAVEQARRADASL"
     misc_feature    complement(2868..2882)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.65"
                     /tool="antismash"
     gene            3014..3607
                     /locus_tag="CVV72_RS08880"
                     /old_locus_tag="CVV72_08845"
     CDS             3014..3607
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020635556.1"
                     /locus_tag="CVV72_RS08880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CVV72_08845"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_219151945.1"
                     /transl_table=11
                     /translation="MTTGSVNPRRADTRRNHERILATAAKSLACSGEVSFNAIAKEAEV
                     GVGTVYRHFPTPEALILAVYRREVRQLVEIVPSLLEKYPPEQAFRVWTTDHLAHYMMTK
                     RGLADALRAATAARGELPAGAYQDMVGAVSTLLQANIDAGTVRAGLAPETVLRGLGGLL
                     YLDPKGEWRRDVASLLDLLWHGMGTGPARTSTVD"
     gene            complement(3609..4208)
                     /locus_tag="CVV72_RS08885"
                     /old_locus_tag="CVV72_08850"
     CDS             complement(3609..4208)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004561919.1"
                     /locus_tag="CVV72_RS08885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CVV72_08850"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_219151946.1"
                     /transl_table=11
                     /translation="MLTKKGAATRQRIIEAAADEIRDHGVGAATLDDICRRSGTGKSQL
                     FHYFPEGKEELLLAVAEWEAGRVIEDQQPYLGRLTTWEAWEKWRDVVIRRYRRQGVHCP
                     LGVLITEIGRHTPAAQAVTRQLLEQWQRQVQAGIEDMRESGDIARDVDPVRASAALIAA
                     IQGGVTILMSTGSADHLEAALDLYLDYLRGGVPVPG"
     gene            complement(4267..4734)
                     /locus_tag="CVV72_RS41930"
     CDS             complement(4267..4734)
                     /NRPS_PKS="Domain: PKS_ER (4-153). E-value: 8.6e-08. Score:
                     23.6. Matches aSDomain:
                     nrpspksdomains_CVV72_RS41930_PKS_ER.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028: crotonyl-CoA reductase / alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024989.4"
                     /locus_tag="CVV72_RS41930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="zinc-binding dehydrogenase"
                     /protein_id="WP_370641885.1"
                     /sec_met_domain="ADH_zinc_N (E-value: 2.7e-13, bitscore:
                     49.0, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIGLVSREEKIPVAKKAGADHVLVSTGSGFERQVRELTGGEGAQV
                     VYDGGGSATFHSSQLSLRRHGVHAYYGVVNGNPVFRPADLPSSILLSYPSVVDHVPTRE
                     ALVRRTDELFEFIRKGQVAPFIGGRYALADAARAHRDIESRRTSGKLLLMP"
     aSDomain        complement(4276..4722)
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CVV72_RS41930_PKS_ER.1"
                     /evalue="8.60E-08"
                     /label="CVV72_RS41930_PKS_ER.1"
                     /locus_tag="CVV72_RS41930"
                     /protein_end="153"
                     /protein_start="4"
                     /score="23.6"
                     /tool="antismash"
                     /translation="VSREEKIPVAKKAGADHVLVSTGSGFERQVRELTGGEGAQVVYDG
                     GGSATFHSSQLSLRRHGVHAYYGVVNGNPVFRPADLPSSILLSYPSVVDHVPTREALVR
                     RTDELFEFIRKGQVAPFIGGRYALADAARAHRDIESRRTSGKLLL"
     gene            complement(<5024..5434)
                     /locus_tag="CVV72_RS41935"
                     /pseudo=""
     CDS             complement(<5024..5434)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF019845.4"
                     /locus_tag="CVV72_RS41935"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MMVGAVDVARHHASHVLHRHQPGEVVHRLPSFGEVDPAENADEKM
                     YRQVQSCAPGSVLAGTFFRTYVGLMHAIHISEYGGPEVMTWTEFPDPVPRPGEVGVRLK
                     VAGVNFMDTGARKMPLPTWSVPTVLGVEGMGVV"
     gene            5402..5806
                     /locus_tag="CVV72_RS08895"
                     /old_locus_tag="CVV72_08860"
     CDS             5402..5806
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024966.4"
                     /locus_tag="CVV72_RS08895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CVV72_08860"
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="WP_255632763.1"
                     /transl_table=11
                     /translation="MARYVYSADHHRWDDLAALFTPDAPFLASTVDGSTQARMTGRDEI
                     AGRLKARNQADSVLVHHLFSSEIDIESPDSAAGVWAMEDIVTTPHDGEMHGYGHYRVRF
                     TRSDGRWLIAELRITRLRLDWTHPDKENRP"
     gene            5803..7014
                     /locus_tag="CVV72_RS08900"
                     /old_locus_tag="CVV72_08865"
     CDS             5803..7014
                     /EC_number="3.-.-.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Abhydrolase_1 (93-200). E-value:
                     1.9e-13. Score: 42.5. Matches aSDomain:
                     nrpspksdomains_CVV72_RS08900_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016334365.1"
                     /locus_tag="CVV72_RS08900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CVV72_08865"
                     /product="epoxide hydrolase family protein"
                     /protein_id="WP_219151947.1"
                     /sec_met_domain="PF00561 (E-value: 6.2e-09, bitscore: 34.7,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTLEPFVIDVEQDVLDDLRRRLKATRFAPDLDNEDEAFGLSTAYL
                     KPIVEYWADGFDWRAVEARLNEYSHHRVEVDGTPVHFIREPGKGPAPIPLLLMHGWPWT
                     FWDWSKVIRPLADPAAHGGDPADAFDVIVPSLPGFAFSTPLTNGKENFVSMADRFHTLM
                     TDVLGHRRFGVGAADYGALVGAQLGHKYAASLHGLHLGNEMPLTIFQGARHWDLTGGAP
                     VDDLPAGPRADMVNFVDTYVSHVATHMLDAQTITHGLNDSPIGMLAWILKRWKKWSDQN
                     GVFEDSYPLDHILTNATIYWVNQAIGSSIRAYKNVNRHPWRPSHDRTPAVEAPTGFTFH
                     LGDAAPPGAHDRERRIAAFKEAAGPVYADVRQVNVHEKGGHFGPWEHPEAWIEDLRATF
                     RPLR"
     aSDomain        6082..6402
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CVV72_RS08900_Abhydrolase_1.1"
                     /evalue="1.90E-13"
                     /label="CVV72_RS08900_Abhydrolase_1.1"
                     /locus_tag="CVV72_RS08900"
                     /protein_end="200"
                     /protein_start="93"
                     /score="42.5"
                     /tool="antismash"
                     /translation="PLLLMHGWPWTFWDWSKVIRPLADPAAHGGDPADAFDVIVPSLPG
                     FAFSTPLTNGKENFVSMADRFHTLMTDVLGHRRFGVGAADYGALVGAQLGHKYAASLHG
                     LHL"
     gene            complement(7025..8764)
                     /locus_tag="CVV72_RS08905"
                     /old_locus_tag="CVV72_08870"
     CDS             complement(7025..8764)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055: pyruvate oxidase/decarboxylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020636738.1"
                     /locus_tag="CVV72_RS08905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CVV72_08870"
                     /product="pyruvate dehydrogenase"
                     /protein_id="WP_219151949.1"
                     /sec_met_domain="TPP_enzyme_N (E-value: 6.7e-39, bitscore:
                     132.1, seeds: 75, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 3.4e-39, bitscore:
                     132.9, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAKPNVAEQFVQVLVQAGVERIYGVVGDSLNPVVDAIRRTPGIEW
                     VHVRNEEAGAFAAAAEAQLTGRLAVCAGSCGPGNTHLVQGLYDAHRTGAPVLALASHIP
                     SGQIGTGFFQETHPERLFVDCSGYCEQISGPAQMPRVLRIAMQHAVSRGEVSVLVLPGD
                     VAHLDAVAPTGSGAPVTEHGTIVPPEAQVTRLAELINDAETVTLFAGAGVRGAHAEVME
                     LAGTVQAPVGHSLRGKEWIQYDNPYDVGMSGLLGYGACYRAMQDADLLVLLGTDFPYDS
                     FLPQARTVQVDHDATRLGRRTPLELAVHGDVRETLRAVQPLLRRKTDRTFLDRMLRDHC
                     KTLEQVVDAYTRNVERHVPIHPEFAADLLDELAADDAIFTVDTGMCNVWAARYLTPNGR
                     RRVIGSFLHGTMANALPHAIGAQFAYPGRQVVSMSGDGGLGMLLGELLTVALHDLPVKI
                     VTFNNSSLGMVKLEMLVDGLPDYQTDHRPVDFAAIASGAGLRAERVTDPTRLRAALKEA
                     LSHDGPALVDVVTDPNALSVPPHITAGQLGGFALAASKVVLEGGVGRMIDLARANLRNI
                     PRL"
     gene            complement(9086..9676)
                     /locus_tag="CVV72_RS08910"
                     /old_locus_tag="CVV72_08875"
     CDS             complement(9086..9676)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027: isochorismatase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020635563.1"
                     /locus_tag="CVV72_RS08910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CVV72_08875"
                     /product="isochorismatase family protein"
                     /protein_id="WP_219151951.1"
                     /transl_table=11
                     /translation="MTSTTLREISTLPTTPATLSDATVILVDYQNTYTRGVMELDGWEA
                     ALDEAATLLARARAEGATVIHVMHDGGEGSPYDLGQDIGRIHERVAPGPGEEIVVKTAP
                     NSFVGTRLGELVDAAGHQNVVVAGFMTHMCVTFTAEGAFLRGNAPTVVAGACATRALPS
                     VAGPVTAADQHRAALATIGDLYAVVVGSSAELG"
     gene            9798..10769
                     /locus_tag="CVV72_RS08915"
                     /old_locus_tag="CVV72_08880"
     CDS             9798..10769
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1287: AraC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005159963.1"
                     /locus_tag="CVV72_RS08915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CVV72_08880"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_255632603.1"
                     /transl_table=11
                     /translation="MNAPSVAVLTFEGINPFHLAVPSLVWGPESPAGDMEPWPITVAAV
                     TPGRLTTSAGYSIDVPAGLGALAEADIVVVPWWSDPESPTPAPVAAALRGAHERGALVV
                     GLCLGVFALADAGILDGRTATTHWKWVETFRRRFPSVRLRPEELYVDEGDIVTGAGATA
                     GIDTCLHLLARTAGQVAANRVARRIVAAPHRPGGQAQFIELPVPEKDDDPLTTVMNWAR
                     SHPDVPHGIDDLAARAHMSRSTFTRSFRARTGATVHSWLVAQRLARARHLLETTALGID
                     AVAAQSGFGTAARLREHFATALGTTPTRYRVEFSAGKSFSPS"
     gene            complement(11164..11529)
                     /locus_tag="CVV72_RS08920"
                     /old_locus_tag="CVV72_08885"
     CDS             complement(11164..11529)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1058: ArsR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020660069.1"
                     /locus_tag="CVV72_RS08920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CVV72_08885"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_219151953.1"
                     /transl_table=11
                     /translation="MNSPLYQATAEFFKTLGHPVRIRVLELLSEREHHVSELLADLGIE
                     PANLSQQLAVLRRANLVVPRKEGTTVSYSLTSPSVAELLAVTRGILTGLITGQLGLLDD
                     LQNSTGVSGGAHSSETD"
     misc_feature    11676..11690
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.24"
                     /tool="antismash"
     misc_feature    complement(11681..11694)
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: medium, score: 18.28"
                     /tool="antismash"
     gene            11795..12457
                     /locus_tag="CVV72_RS08925"
                     /old_locus_tag="CVV72_08890"
     CDS             11795..12457
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016334370.1"
                     /locus_tag="CVV72_RS08925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CVV72_08890"
                     /product="hypothetical protein"
                     /protein_id="WP_219151955.1"
                     /transl_table=11
                     /translation="MTTRHSLPAAATRAHLVLAAHAAELADLAANAARVDATGEQDTGS
                     TRDRSSLIEMAQQILEAAVVAARLDGKTWEEIACGLDGATPRSVRTRYWPSVARFRADP
                     FPSQDARHENMAEHTEQTAFRLRRLPTPDRRPEAESTTGPTPHLALVTVPAEQGDGEAV
                     REPAAADARLKIAERLVAAYERIATNDRRPPQWILDGLAHARHTAAALRAHAGTPPE"
     gene            complement(12472..12621)
                     /locus_tag="CVV72_RS08930"
     CDS             complement(12472..12621)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005159959.1"
                     /locus_tag="CVV72_RS08930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_167373467.1"
                     /transl_table=11
                     /translation="MIAESANQQSVTFPQEATPIFDLVAKMVARTKTEDEHDFDREAGL
                     ATPV"
     gene            complement(12748..13554)
                     /gene="map"
                     /locus_tag="CVV72_RS08935"
                     /old_locus_tag="CVV72_08895"
     CDS             complement(12748..13554)
                     /EC_number="3.4.11.18"
                     /GO_function="GO:0070006 - metalloaminopeptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene="map"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1172: methionine aminopeptidase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007032696.1"
                     /locus_tag="CVV72_RS08935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CVV72_08895"
                     /product="type I methionyl aminopeptidase"
                     /protein_id="WP_219151957.1"
                     /transl_table=11
                     /translation="MIELKTPAEIERMQVTGRFVAEVLTEVGDLADVGVNLMDLEHHVR
                     GMIERRGAESCYWDYAPSFGKGPFRNVICLAVNDAVLHGLPHDYTLHDGDVLTADLAVK
                     IDGWAADSARTVIVGTPAEEDLRIVRATEEALEAAIEAARPGNRLGDISAAIWAVARAH
                     GYPVNTEFGGHGIGRTMHEELHIPNKGKAGRGLKLQPGLTVALEPWFARTTDRIVFDDD
                     GWTIRSADGSRAAHSEHTVAITEGAPLVLTRREREVAADRISAKGS"
     misc_feature    complement(13574..13587)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 15.96"
                     /tool="antismash"
     misc_feature    13575..13588
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 15.92"
                     /tool="antismash"
     misc_feature    complement(13609..13622)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 15.92"
                     /tool="antismash"
     misc_feature    13610..13623
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 15.96"
                     /tool="antismash"
     misc_feature    complement(13612..13625)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 14.51"
                     /tool="antismash"
     gene            complement(13634..15004)
                     /locus_tag="CVV72_RS08940"
                     /old_locus_tag="CVV72_08900"
     CDS             complement(13634..15004)
                     /NRPS_PKS="Domain: Aminotran_3 (49-389). E-value: 3.5e-80.
                     Score: 261.5. Matches aSDomain:
                     nrpspksdomains_CVV72_RS08940_Aminotran_3.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1013: aminotransferase class-III"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016334371.1"
                     /locus_tag="CVV72_RS08940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CVV72_08900"
                     /product="aspartate aminotransferase family protein"
                     /protein_id="WP_219151959.1"
                     /sec_met_domain="Aminotran_3 (E-value: 4.2e-83, bitscore:
                     278.1, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIPTPTARPALVPRVEGALPGPRSAEYLEHQRQWESSARAYPRHL
                     PIAIAGAAGSHLWDMDGNVFLDFLSGAGVLSLGHNHPELVRAATEQLTVLTHGLDFPTP
                     AKREFIDAQLSMLPPGLRSRTRMHFCGPGGANAVDAAIKLCKTATGRGDLVSFQGGFHG
                     SSHAAMALTGLVAQKRPIANGVPGVHFFPYSYCARCPVGLSPDTCETNCVGLLERSLRD
                     PNGGIPLPAAVILEMVQGEGGIIPADRDFVRRVRALTAELDIPLVVDEVQTGCGRTGTW
                     FAFEHYDIEPDVIIASKALSGMGLPVAMIFYDRRLDGWAPGAHSGTFRGNQAAFAAGAA
                     AVHVVRRDDVLGNVRQRGRQLARRLGVLHDHVWVREVRGLGLMWGIELADPRDGRPAGG
                     YARAVQAHALRHGLIVELGGRDDGVIRLMPPLTVTAEEIELACGILLDAIERCHPAQ"
     aSDomain        complement(13838..14857)
                     /aSDomain="Aminotran_3"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CVV72_RS08940_Aminotran_3.1"
                     /evalue="3.50E-80"
                     /label="CVV72_RS08940_Aminotran_3.1"
                     /locus_tag="CVV72_RS08940"
                     /protein_end="389"
                     /protein_start="49"
                     /score="261.5"
                     /tool="antismash"
                     /translation="AGAAGSHLWDMDGNVFLDFLSGAGVLSLGHNHPELVRAATEQLTV
                     LTHGLDFPTPAKREFIDAQLSMLPPGLRSRTRMHFCGPGGANAVDAAIKLCKTATGRGD
                     LVSFQGGFHGSSHAAMALTGLVAQKRPIANGVPGVHFFPYSYCARCPVGLSPDTCETNC
                     VGLLERSLRDPNGGIPLPAAVILEMVQGEGGIIPADRDFVRRVRALTAELDIPLVVDEV
                     QTGCGRTGTWFAFEHYDIEPDVIIASKALSGMGLPVAMIFYDRRLDGWAPGAHSGTFRG
                     NQAAFAAGAAAVHVVRRDDVLGNVRQRGRQLARRLGVLHDHVWVREVRGLGLMWGIELA
                     "
     gene            complement(15001..19065)
                     /locus_tag="CVV72_RS08945"
                     /old_locus_tag="CVV72_08905"
     CDS             complement(15001..19065)
                     /GO_function="GO:1904091 - non-ribosomal peptide synthetase
                     activity [Evidence IEA]"
                     /NRPS_PKS="Domain: AMP-binding (51-440). E-value: 2.6e-100.
                     Score: 327.8. Matches aSDomain:
                     nrpspksdomains_CVV72_RS08945_AMP-binding.1"
                     /NRPS_PKS="Domain: PP-binding (554-618). E-value: 1.9e-10.
                     Score: 32.9. Matches aSDomain:
                     nrpspksdomains_CVV72_RS08945_PP-binding.1"
                     /NRPS_PKS="Domain: TIGR02353 (644-1338). E-value: 1.3e-208.
                     Score: 686.5. Matches aSDomain:
                     nrpspksdomains_CVV72_RS08945_TIGR02353.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NAPAA:
                     TIGR02353"
                     /gene_functions="biosynthetic (rule-based-clusters) NAPAA:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016334372.1"
                     /locus_tag="CVV72_RS08945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CVV72_08905"
                     /product="Pls/PosA family non-ribosomal peptide synthetase"
                     /protein_id="WP_219151961.1"
                     /sec_met_domain="AMP-binding (E-value: 3.5e-109, bitscore:
                     364.0, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 2.2e-07, bitscore:
                     30.2, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR02353 (E-value: 1.7e-206, bitscore:
                     686.5, seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSPYGQPSGQFTTDGLVLTCDGHEQRVRWRTGDRLERLYERLCDR
                     LRDTGLGDRLAVDAGGVKVTFGGLDERANRLARHLLAHGVRPGDRIGLLFTEPVHPYVA
                     MLAVLKVNAAYVPLDAGFPDDRLAYIVQDAGVRLVISTSGLRERFEPDAVDLVCLDVDS
                     DRIAALPGTRLSADERGTPADELCYVVYTSGSTGRPKGVTIDHASICNFVLVAADVYGI
                     QDTDRVYQGMTIAFDFSVEEIWVPLLSGATLVPKPGGAALVGHDLLEFLRENRVTALCC
                     VPTLLASLDEDLPLLRFLLVSGEACPEDLVRRWYRADRRFLNVYGPTEATVTATWSVLR
                     PDRPVTIGVPLPTYSVVILDPDEPVALAAGELGEIGIAGIGLAGGYLNRPDLTERAFIP
                     DFLGIGHNPSRRIYRTGDLGRITPDGEIEYHGRADTQVKIRGYRVELTEIESVLLRIPG
                     IAQAVVETHHPEAGTTELVAYYSLRRDNEDVDPGELRRRLAELLPGYMVPAYLEQLDHI
                     PLTPAGKADRKHLPAPSSPRRVGNDVDYVAPATKTELRLAEALSGVLGIEPVSVTGHFF
                     DDYGADSLLLAKFCAVVRERGEVASLSARDVYLNPTIRGLAESTASAVEATVARAEEPR
                     RASTTSYVLCGVFQLLAFLAYAAGSGWLLDTGFRWIDAATGFAESYARAAGLGFVVFVV
                     LSVVPVLAKWMLVGRWKPGEIPLWSVGYLRFWTVKALVRFSPLMLFVGTPLYSWYLRAL
                     GADIGKGALILSRNPPVCTDLLSVGAGAVIRKDAYFSCYRARAGRIQTGTVTLGANAFV
                     GEMTVLDIGSALGDGAQLGHSSSLHSGQSVPDGESWHGSPARLSTVDYRALGTVARGRL
                     RPIVFCASSLLLLLLGTLPLSLGGAGVLVEQWFTTTVDFTSWAFYLGRIADSALVYFGA
                     LLAGLAVVLVLPRLLGLFLRPDHVYPLYGRHFAIQRLIARLTNLRAYTYLFGDSSYIVY
                     YLRALGYDLSKVHQTGSNFGVEVKHETPFLSTVGTGTMVSDGLSLLNADFSASSFRLRK
                     TSVAPQAFLGNEIAFPPGARIGRNCLLATKVLVPLDGPVRENVGLLGSPAFEIPRTVRR
                     DTGFEHLGTGDALRRGLRAKNRHNTVTIGVYLLVHWLHLFGVLLIGAVAGALHGRLGPL
                     AVGGGIVATLAFSVAFLMLAELAVQGFRAMRPLFCSIYDPAFWRHERFWKLSPARYLAL
                     FNGTPFKPFLLRRLGVRIGRRVFDDGCAIPERSLVSIGDDCVLNLHTVAQGHSLEDGTF
                     KSDHITIGAGCTLGVGAFVHYGVTMADGAIAEADAFLMKGTAVPARTRWHANPAVELDT
                     ADEIAATRRLP"
     aSDomain        complement(15052..17133)
                     /aSDomain="TIGR02353"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CVV72_RS08945_TIGR02353.1"
                     /evalue="1.30E-208"
                     /label="CVV72_RS08945_TIGR02353.1"
                     /locus_tag="CVV72_RS08945"
                     /protein_end="1338"
                     /protein_start="644"
                     /score="686.5"
                     /tool="antismash"
                     /translation="CGVFQLLAFLAYAAGSGWLLDTGFRWIDAATGFAESYARAAGLGF
                     VVFVVLSVVPVLAKWMLVGRWKPGEIPLWSVGYLRFWTVKALVRFSPLMLFVGTPLYSW
                     YLRALGADIGKGALILSRNPPVCTDLLSVGAGAVIRKDAYFSCYRARAGRIQTGTVTLG
                     ANAFVGEMTVLDIGSALGDGAQLGHSSSLHSGQSVPDGESWHGSPARLSTVDYRALGTV
                     ARGRLRPIVFCASSLLLLLLGTLPLSLGGAGVLVEQWFTTTVDFTSWAFYLGRIADSAL
                     VYFGALLAGLAVVLVLPRLLGLFLRPDHVYPLYGRHFAIQRLIARLTNLRAYTYLFGDS
                     SYIVYYLRALGYDLSKVHQTGSNFGVEVKHETPFLSTVGTGTMVSDGLSLLNADFSASS
                     FRLRKTSVAPQAFLGNEIAFPPGARIGRNCLLATKVLVPLDGPVRENVGLLGSPAFEIP
                     RTVRRDTGFEHLGTGDALRRGLRAKNRHNTVTIGVYLLVHWLHLFGVLLIGAVAGALHG
                     RLGPLAVGGGIVATLAFSVAFLMLAELAVQGFRAMRPLFCSIYDPAFWRHERFWKLSPA
                     RYLALFNGTPFKPFLLRRLGVRIGRRVFDDGCAIPERSLVSIGDDCVLNLHTVAQGHSL
                     EDGTFKSDHITIGAGCTLGVGAFVHYGVTMADGAIAEADAFLMKGTAVPARTRWHANPA
                     "
     aSModule        complement(15052..18912)
                     /complete
                     /domains="nrpspksdomains_CVV72_RS08945_AMP-binding.1"
                     /domains="nrpspksdomains_CVV72_RS08945_PP-binding.1"
                     /domains="nrpspksdomains_CVV72_RS08945_TIGR02353.1"
                     /locus_tags="CVV72_RS08945"
                     /monomer_pairings="X -> X"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(15601..15627)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CVV72_RS08945_0007"
                     /evalue="9.90E+01"
                     /label="NRPS-A_a2"
                     /locus_tag="CVV72_RS08945"
                     /protein_end="1155"
                     /protein_start="1146"
                     /score="-3.6"
                     /tool="antismash"
                     /translation="FGVLLIGAV"
     misc_feature    complement(15694..15696)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     CDS_motif       complement(15814..15849)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CVV72_RS08945_0006"
                     /evalue="3.80E+01"
                     /label="NRPS-A_a2"
                     /locus_tag="CVV72_RS08945"
                     /protein_end="1084"
                     /protein_start="1072"
                     /score="-1.1"
                     /tool="antismash"
                     /translation="CLLATKVLVPLD"
     CDS_motif       complement(16249..16281)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CVV72_RS08945_0005"
                     /evalue="5.40E+01"
                     /label="NRPS-A_a2"
                     /locus_tag="CVV72_RS08945"
                     /protein_end="939"
                     /protein_start="928"
                     /score="-1.6"
                     /tool="antismash"
                     /translation="GALLAGLAVVL"
     aSDomain        complement(17212..17403)
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CVV72_RS08945_PP-binding.1"
                     /evalue="1.90E-10"
                     /label="CVV72_RS08945_PP-binding.1"
                     /locus_tag="CVV72_RS08945"
                     /protein_end="618"
                     /protein_start="554"
                     /score="32.9"
                     /tool="antismash"
                     /translation="RLAEALSGVLGIEPVSVTGHFFDDYGADSLLLAKFCAVVRERGEV
                     ASLSARDVYLNPTIRGLAE"
     CDS_motif       complement(17716..17781)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CVV72_RS08945_0004"
                     /evalue="2.60E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="CVV72_RS08945"
                     /protein_end="450"
                     /protein_start="428"
                     /score="35.5"
                     /tool="antismash"
                     /translation="YHGRADTQVKIRGYRVELTEIE"
     aSDomain        complement(17746..18912)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CVV72_RS08945_AMP-binding.1"
                     /evalue="2.60E-100"
                     /label="CVV72_RS08945_AMP-binding.1"
                     /locus_tag="CVV72_RS08945"
                     /protein_end="440"
                     /protein_start="51"
                     /score="327.8"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="GDRLAVDAGGVKVTFGGLDERANRLARHLLAHGVRPGDRIGLLFT
                     EPVHPYVAMLAVLKVNAAYVPLDAGFPDDRLAYIVQDAGVRLVISTSGLRERFEPDAVD
                     LVCLDVDSDRIAALPGTRLSADERGTPADELCYVVYTSGSTGRPKGVTIDHASICNFVL
                     VAADVYGIQDTDRVYQGMTIAFDFSVEEIWVPLLSGATLVPKPGGAALVGHDLLEFLRE
                     NRVTALCCVPTLLASLDEDLPLLRFLLVSGEACPEDLVRRWYRADRRFLNVYGPTEATV
                     TATWSVLRPDRPVTIGVPLPTYSVVILDPDEPVALAAGELGEIGIAGIGLAGGYLNRPD
                     LTERAFIPDFLGIGHNPSRRIYRTGDLGRITPDGEIEYHGRADTQVKIR"
     CDS_motif       complement(17875..17961)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CVV72_RS08945_0003"
                     /evalue="2.40E-10"
                     /label="NRPS-A_a6"
                     /locus_tag="CVV72_RS08945"
                     /protein_end="397"
                     /protein_start="368"
                     /score="32.7"
                     /tool="antismash"
                     /translation="AGELGEIGIAGIGLAGGYLNRPDLTERAF"
     CDS_motif       complement(18448..18507)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CVV72_RS08945_0002"
                     /evalue="3.80E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="CVV72_RS08945"
                     /protein_end="206"
                     /protein_start="186"
                     /score="28.6"
                     /tool="antismash"
                     /translation="CYVVYTSGSTGRPKGVTIDH"
     CDS_motif       complement(18709..18750)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CVV72_RS08945_0001"
                     /evalue="1.70E-04"
                     /label="NRPS-A_a2"
                     /locus_tag="CVV72_RS08945"
                     /protein_end="119"
                     /protein_start="105"
                     /score="14.9"
                     /tool="antismash"
                     /translation="LAVLKVNAAYVPLD"
     gene            complement(19062..20204)
                     /locus_tag="CVV72_RS08950"
                     /old_locus_tag="CVV72_08910"
     CDS             complement(19062..20204)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007032699.1"
                     /locus_tag="CVV72_RS08950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CVV72_08910"
                     /product="aspartate kinase"
                     /protein_id="WP_255632604.1"
                     /transl_table=11
                     /translation="MAAEVAAIAATGDRVVLVVSAMGDSTDRLIALAGEVAEPPAPREL
                     DQLMATGEQASAAMLAMALTERGVEAVSLSGDQAGIEVAGEPGSGTIVSVDPGRIVARL
                     RDAQVVVVAGFQGRNADGELLTLGRGGSDTTAVALAAALGGTECEIRTDVHGVRTADPR
                     IVRDTRPVRTISYDAMAELAGVGARVLHPRSVDLARRHGVAVRVKHSSDPGPSTVVKAG
                     EEPLEDTPRVIGIAHERDVRLVRVEVSASDPDRYARVLAMLADCGVRPDNLSWPDPGEL
                     RFTVRGTEPLGPPITRLAMELEARSTVCEELGSVSVVGTALLDPPGFLPELLRILAGHR
                     VTVPAMTTSRSRLTAVVPADVVDTTVRALHDSFGLAEDGA"
     misc_feature    complement(20310..20323)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 15.67"
                     /tool="antismash"
     misc_feature    complement(20629..20643)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.52"
                     /tool="antismash"
     gene            complement(20792..21475)
                     /locus_tag="CVV72_RS08955"
                     /old_locus_tag="CVV72_08915"
     CDS             complement(20792..21475)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016334375.1"
                     /locus_tag="CVV72_RS08955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CVV72_08915"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_219151965.1"
                     /transl_table=11
                     /translation="MSLNLTGVTLTYPDGDTRLTALDDVTVEVPAGTLTAVAGPSGSGK
                     SSLLAVAATLITPDRGTVTVDGTTTTGLNRGELAELRRRKIGIVFQQPNLLPALTAAEQ
                     LQVMARIDGRSAAGARGVAMDLLDAVGLAAQAGRRPHQLSGGQRQRVNIARALMNEPTV
                     LLIDEPTSALDHERGAAVVDLIAGLTRERATATVLVTHDRVHLAAVDRIVEVHDGRLGS
                     PSPVG"
     gene            complement(21472..22554)
                     /locus_tag="CVV72_RS08960"
                     /old_locus_tag="CVV72_08920"
     CDS             complement(21472..22554)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005159890.1"
                     /locus_tag="CVV72_RS08960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CVV72_08920"
                     /product="ABC transporter permease"
                     /protein_id="WP_219151967.1"
                     /transl_table=11
                     /translation="MFVAWRDLRFAKGRFALMGAVVVLITLLVGLLSGLTAGLGEQNTS
                     AITGLPADKIVFAAPAAGQSLSYANSAITDTQRRQWAETPGVTAAEPLGIATTKAVAGD
                     RSAGISVFGVRTGSALAPDSEKISGDSVVLSTSAAEDLGVRSGDTVAVAGRPLTVAAVA
                     GDAWFSHTPVIWAGLDVWAKTAPPADGEPSATVLALTTTAGADLAATDLTAGTTTVSKG
                     DSLSAIGSYTSENGSLQLMRGFLFAISALVIGAFFTVWTIQRSGDIAVLKALGASTAFL
                     LKDALGQAVVLLVGGTAIGTGLAVGLGTVVAGSAVPFLLTPATVLVPSAVMILLGALGA
                     ALSVRRITSVDPLTALGSAR"
     gene            22722..23888
                     /locus_tag="CVV72_RS08965"
                     /old_locus_tag="CVV72_08925"
     CDS             22722..23888
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007032702.1"
                     /locus_tag="CVV72_RS08965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CVV72_08925"
                     /product="sensor histidine kinase"
                     /protein_id="WP_219151969.1"
                     /transl_table=11
                     /translation="MTAASALTPTSRVLTWCLHLLLIALLTLAAARAVADGSPDAGTIV
                     AAAVTCAAVYAAGPLLPRVRTSRRAALWWLIAVGLVWLVLLVLTADGVWVAFPLYFLQL
                     HLLPRRQGLVAVIATALAAITAFAAHQGSFAPAAAIGPALGAAVAVAVVWGYQALYRES
                     ERRRNLIEELTATRADLAAAQHEAGVLAERERLAHEIHDTLAQGLSSIQLLLRAAERTL
                     PDTAGNAARYVEQARQAAADNLAEARRFVVALSPPALDDTTLADALARLCATTTARHRI
                     TARFHLTGDPVPLPTAHEVVLLRIGQAALANTVRHADASTAEVTLSYDGDQVTLVVVDD
                     GVGFDPDHSGFGLTAMRTRAEALDGIFTVESSPGHGTTVSARLPKECP"
     gene            23885..24520
                     /locus_tag="CVV72_RS08970"
                     /old_locus_tag="CVV72_08930"
     CDS             23885..24520
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005159887.1"
                     /locus_tag="CVV72_RS08970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CVV72_08930"
                     /product="response regulator transcription factor"
                     /protein_id="WP_304511405.1"
                     /transl_table=11
                     /translation="MTEPPIRLLLADDHPIVRAGLRAVLETEPGLVVSAEAATAEEAVA
                     RAAEGDIDVVLMDLRFGSGMTGAEATAAITARPDAPRVLIVTTYDTDADTLPAIEAGAT
                     GYLLKDAPPEDLAAAVRTAAAGRTTLAPTVADRLMNRMRMPATALTLREIEVLGLVADG
                     LSNRAIADRLHLTEGTVKSHLARSYTKLGVDSRTAAVATATDLGLIRR"
     gene            complement(24723..25895)
                     /gene="aztD"
                     /locus_tag="CVV72_RS08975"
                     /old_locus_tag="CVV72_08940"
     CDS             complement(24723..25895)
                     /codon_start=1
                     /gene="aztD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020635593.1"
                     /locus_tag="CVV72_RS08975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CVV72_08940"
                     /product="zinc metallochaperone AztD"
                     /protein_id="WP_219151973.1"
                     /transl_table=11
                     /translation="MARKARYLALMATTASTLALAACGTEQPAAEPGKDAAPASVVADP
                     VAVTYDGGIVLLDGKTLKEAKNLPLEGFNRLNPAGNDRHLLVSTSTGFRVLDAVGAVLT
                     DNEVKAAKPGHVVRHAGKTVLFADGTGEVTVFDPKTIGTAAFPAPKHKTPEAHHGVAVE
                     LANGELLTTVGNEDKRSGIVVLDKDKKEIARNEQCPGVHGEAAARGEAVVVGCQTGVLI
                     YRNGVITKVTSPDPYGRIGNQAGSDVSPITLGDYKVDEAAELERPTRISLIDTEKATLK
                     HVDIGTSYTFRSLARGPQGEALVLGTDGQIHVIDPVSGAVTRKIAVLGTWQEPIEWQQP
                     RPAIFVRGGTAYVTDPGKKEIHSVDLASGTKTATGTIPGTPNEVSGVLGH"
     gene            complement(25922..26821)
                     /gene="aztC"
                     /locus_tag="CVV72_RS08980"
                     /old_locus_tag="CVV72_08945"
     CDS             complement(25922..26821)
                     /GO_component="GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /gene="aztC"
                     /gene_functions="transport (smcogs) SMCOG1252: cation ABC
                     transporter, periplasmic"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007032705.1"
                     /locus_tag="CVV72_RS08980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CVV72_08945"
                     /product="zinc ABC transporter substrate-binding protein
                     AztC"
                     /protein_id="WP_219151974.1"
                     /transl_table=11
                     /translation="MRRRVLALVVVAVLAAAGCSGTGGGGKSVVVTTNILGDITRAVVG
                     DQAEVTVLMKPNADPHSFGISAQQAAQVERAGLIVYNGLGLEEGILRTVRTAEQSGVPA
                     LPAGERVNPISYADNKPDPHFWTDPARVRDAVKTIADEVVAHVDGVDEAVIRANAERYR
                     GEIEALDKAMTEKFGGIPPERRKLVTNHHVFGYLAQRFGFQVVGAVIPGGTTLASPSSS
                     DLKALADTVRAAGVPVIFADSSQPDRLARVLAEQAGLHVQVAPLFSESLSEPGQGAATY
                     LEMMRANTESITTGLTRS"
     gene            complement(26818..28014)
                     /locus_tag="CVV72_RS08985"
                     /old_locus_tag="CVV72_08950"
     CDS             complement(26818..28014)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016334381.1"
                     /locus_tag="CVV72_RS08985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CVV72_08950"
                     /product="hypothetical protein"
                     /protein_id="WP_219151976.1"
                     /transl_table=11
                     /translation="MKLKAVTAVVAALTLAACGSEQPGEVTAEVPHGYVEGAEEAAEAQ
                     SRLIVADTDTGAVRVVDLITEEVHEAGRVDGVQAVTGDGRFGYLTAGDGTIRVIDSGSW
                     MVDHGDHVHYYRAKVRDVGVAPGKQPLAVYSDPAVTALSYSDGTTTLLDRTALDKGTVT
                     ELGKITREPHASVAIPYREHIIATVADAGKTLARGVRVHDRQGKVVAEIDQPCPDLRGQ
                     AVTRRGAVFGCADGALLVTEKDGAFSGVKIPYPRDVSAQERATAFSHRPGGSTLAARAG
                     ESAVWSLDVGRRSWQHVETGPVAAVNAVGEGGPLLVLTRDGKLRSFDGTGKEQTAVPLL
                     TPEATAAGVPSIQVDSTRAYLNNPLSAEVYEIDYNDNLRRARTLKVGGKAGHIVETGR"
     gene            complement(28011..28862)
                     /gene="aztB"
                     /locus_tag="CVV72_RS08990"
                     /old_locus_tag="CVV72_08955"
     CDS             complement(28011..28862)
                     /codon_start=1
                     /gene="aztB"
                     /gene_functions="other (smcogs) SMCOG1245: ABC transporter
                     protein, integral membrane"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016334382.1"
                     /locus_tag="CVV72_RS08990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CVV72_08955"
                     /product="zinc ABC transporter permease AztB"
                     /protein_id="WP_219151978.1"
                     /transl_table=11
                     /translation="MDWLLIPFEVSFVQRALVAGVLVSAVCAVVGTWVVLRGMAFIGDA
                     MSHGMLPGVAIASLTGVNLLIGAAISAGVMALGVTALGRSRRLSEDTTIGLLFVGMLAS
                     GVIIVSHSRSFAVDLTGFLFGDVLAVGSGDLVGLAVTLLVVGAVALAGHRSFTALTFDV
                     RKAHTLGLRPRLANAVLLGLVTLTIVASFRVVGTLLVFGLLIAPAAAALFWSRRITTIM
                     LIAALLGVAATLGGLLVSWHWGTAAGATIAAGAVLLFFLSAFLSFVRQRFRSLTPEIES
                     SR"
     misc_feature    28875..28890
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 19.86"
                     /tool="antismash"
     misc_feature    complement(28877..28890)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 15.85"
                     /tool="antismash"
     misc_feature    complement(28877..28891)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 21.0"
                     /tool="antismash"
     misc_feature    28878..28891
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 15.71"
                     /tool="antismash"
     misc_feature    complement(28878..28893)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: medium, score: 23.97"
                     /tool="antismash"
     misc_feature    28881..28896
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 23.56"
                     /tool="antismash"
     misc_feature    complement(28883..28896)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 14.95"
                     /tool="antismash"
     misc_feature    28883..28897
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 19.08"
                     /tool="antismash"
     misc_feature    complement(28890..28904)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 18.95"
                     /tool="antismash"
     gene            28910..29677
                     /gene="aztA"
                     /locus_tag="CVV72_RS08995"
                     /old_locus_tag="CVV72_08960"
     CDS             28910..29677
                     /codon_start=1
                     /gene="aztA"
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020635597.1"
                     /locus_tag="CVV72_RS08995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CVV72_08960"
                     /product="zinc ABC transporter ATP-binding protein AztA"
                     /protein_id="WP_219151980.1"
                     /transl_table=11
                     /translation="MTPDTAALTIDRAHAHYGSREVLRGITAQVPSARLTAIAGANGAG
                     KSSLLNLVAGVLPPTTGSVTRGDQGRVAYVTQQSEVSRSLPITVRATVTMGRWAHRGHW
                     RRLSKMDRKIVEECLELLEITSIADRLIGTLSGGQRQRALVAQGLAQRAGLLLLDEPSA
                     GLDLHARGLIEKALRATLAEGTTVLRVTHDLEVAGRADHCLLLQDGRLVGEGVPASVLT
                     PARVAEAWGLPVIGDAALDVHGTPGAHPIRPVQ"
     gene            29717..30487
                     /locus_tag="CVV72_RS09000"
                     /old_locus_tag="CVV72_08965"
     CDS             29717..30487
                     /EC_number="3.1.-.-"
                     /GO_function="GO:0016788 - hydrolase activity, acting on
                     ester bonds [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016334249.1"
                     /locus_tag="CVV72_RS09000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CVV72_08965"
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="WP_219151982.1"
                     /transl_table=11
                     /translation="MPSAISKRLVTLGDSFTEGVGDDDPSSPNGVRGWADRVAATLAAN
                     HQDFRYANLAIRGKLLGQVLAEQLDPALALNPDVVTLYAGGNDLMRPKVDIDALLDDYD
                     AAVGKVVATGARVVLFTGVDGVEDALFRRIRGRVAIYNEHVRGIAARHETLLVDMWAMR
                     QLRDRRLWAPDRLHLNSLGHNEIAIAVLDALGEPHKLTPAELGPRPLLSPRARRTENLQ
                     WGKEHAVPWIKRRLRGESSGDELAPKRPTMDPYA"
     misc_feature    29741..29743
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(30478..31050)
                     /locus_tag="CVV72_RS09005"
                     /old_locus_tag="CVV72_08970"
     CDS             complement(30478..31050)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007034533.1"
                     /locus_tag="CVV72_RS09005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CVV72_08970"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_125678004.1"
                     /transl_table=11
                     /translation="MTDEKPLRADARRNRTRVLEAAERVFTAKGTSAPTEEVAREAGVG
                     VGTVFRHFPTKEALLEAVLFARLHRFVDEAEATVAADSPDPGAAFFGFLTGWIEMSGAK
                     NAYFEALSAAGVSVPSAGSVIGVRLKDALGVLLSRAQDTGDVRKDLGVDELIPVIIGTA
                     KAAEHAGPEFRARTICILFDGLRPRQA"
     gene            complement(31097..31480)
                     /locus_tag="CVV72_RS09010"
                     /old_locus_tag="CVV72_08975"
     CDS             complement(31097..31480)
                     /NRPS_PKS="Domain: Polyketide_cyc2 (1-122). E-value: 3e-08.
                     Score: 26.1. Matches aSDomain:
                     nrpspksdomains_CVV72_RS09010_Polyketide_cyc2.1"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007034534.1"
                     /locus_tag="CVV72_RS09010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CVV72_08975"
                     /product="SRPBCC domain-containing protein"
                     /protein_id="WP_255632607.1"
                     /transl_table=11
                     /translation="MWRALTEPQLLERWLRMSNDIKPVVGHRFELLADPVPAAGFEGGP
                     VACEVLAVEPERLLSISWGPEWTVTWRLVPEGRGTRLFLSHEGFDPDDEFQRMSRRIMG
                     GGWRTGVPKALARVLDEMPDRKT"
     aSDomain        complement(31115..31477)
                     /aSDomain="Polyketide_cyc"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CVV72_RS09010_Polyketide_cyc2.1"
                     /domain_subtypes="Polyketide_cyc2"
                     /evalue="3.00E-08"
                     /label="CVV72_RS09010_Polyketide_cyc2.1"
                     /locus_tag="CVV72_RS09010"
                     /protein_end="122"
                     /protein_start="1"
                     /score="26.1"
                     /tool="antismash"
                     /translation="WRALTEPQLLERWLRMSNDIKPVVGHRFELLADPVPAAGFEGGPV
                     ACEVLAVEPERLLSISWGPEWTVTWRLVPEGRGTRLFLSHEGFDPDDEFQRMSRRIMGG
                     GWRTGVPKALARVLDEM"
     gene            complement(31540..31857)
                     /locus_tag="CVV72_RS09015"
                     /old_locus_tag="CVV72_08980"
     CDS             complement(31540..31857)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1058: ArsR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016334246.1"
                     /locus_tag="CVV72_RS09015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CVV72_08980"
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="WP_125678008.1"
                     /transl_table=11
                     /translation="MPVNDDVFAALANPARREVLGILLDGPRAAGEIAERFDMRRPSLS
                     EHLRVLREAGLVREERQGRNRVYFLEAAPLQEVSDWLSPYERYWRGKLGNLRDLLDEEE
                     F"
     gene            complement(31857..32243)
                     /locus_tag="CVV72_RS09020"
                     /old_locus_tag="CVV72_08985"
     CDS             complement(31857..32243)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007034536.1"
                     /locus_tag="CVV72_RS09020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CVV72_08985"
                     /product="VOC family protein"
                     /protein_id="WP_219151984.1"
                     /transl_table=11
                     /translation="MNIDRIQFLTVPVADQAKARDFYVGKLGFDLLVDVSGPHGPFVMV
                     GPKGAETGIVLVDRAVGGLDLETRVHFQLSTADVDADIAELRAQGIEVDDAEEMPWGRV
                     TSLKDPDGNAMGLLEPSGYGDWPR"
     misc_feature    32258..32274
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 19.42"
                     /tool="antismash"
     gene            32453..33037
                     /locus_tag="CVV72_RS09025"
                     /old_locus_tag="CVV72_08990"
     CDS             32453..33037
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0008752 - FMN reductase (NAD(P)H) activity
                     [Evidence IEA]"
                     /GO_function="GO:0010181 - FMN binding [Evidence IEA]"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0052873 - FMN reductase (NADPH) activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016334244.1"
                     /locus_tag="CVV72_RS09025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CVV72_08990"
                     /product="NADPH-dependent FMN reductase"
                     /protein_id="WP_219151987.1"
                     /transl_table=11
                     /translation="MTAENTTQSPVRLAVIIGSVRHERFADAITGWLLTELAALDGLEV
                     DPIDLADIDLPLQGTQPGGTETVISDRLRAADAYLVVTPEYNHSFPAALKNAIDWHFTE
                     WAYKPVAFVGYGAGSGGIRAIEQLRLIFPELRATTTRDAVLLNAPWTRLGPNGYEGTDA
                     ERGALAATMTELGWWARTLRAGRVATQASAA"
     misc_feature    32834..32836
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(33074..33089)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.5"
                     /tool="antismash"
     misc_feature    complement(33090..33108)
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 21.02"
                     /tool="antismash"
     misc_feature    complement(33992..34006)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 19.61"
                     /tool="antismash"
ORIGIN
        1 gcacggtcag caggcccgtc ccggggtccg ccccgctggt cgcgacgacg gccgtgtcgt
       61 cgggcagcag ggtgatcccg accgtggccg ggaaccgcag tgcggggaac atcgcggtgg
      121 ccgtgcccat gcccacgagc cagtcaccgt ccgtgcgccc ccggggtgcg cgatccgccc
      181 agccgaaccg cgccgcgccg acgcggaagc attcgtcgag gtgtttgctc gaccactgca
      241 gatccttgcc cggcggagcg gtggaattgt tccgctgccg cagctcgatc gggtccatgc
      301 ccagcgtgac ggcgagttcg tcgagtgcgc tctccagcgc gaaggatccc ggtgcctcac
      361 ccggcgcccg catgaaggtg gtcgggggga tgttgagcgg caccatcttc tggctgatgg
      421 ccaggttccg cgtggcgtac cactcgcgcg acgtgccgtg tgatgtcggc tcgacgaacg
      481 accggtccag gggcgtgctg caccacgaat cgtgccgcag cgcgttcagc gtgccatcat
      541 gctccgcgcc gagggcgatc ttctgcaccg tcgcggcgcg gccggcggtc gcggtgaaga
      601 cctgttcccg gctgagcgcg gctttcaccg gcctgcccag caccctggcc gccgccgcgg
      661 cgaggaacgc cggggtggac gtgcggccct tgcccccgaa cgcaccgccg acgaagggat
      721 tcaccgcgtg cacctcggac ggctccaggt ccagcgccat cgccagttcc gccgcctgga
      781 ggttcgaacc ctggttgccg ctgtggatcg tcaagccctc ggggccccac accgcgaccg
      841 cggaatgcgg ttccatcgcg gcgtggtgct gaggcgcggt ggtgtacgtg gcttcgatga
      901 ccaccgggct ctcggcgagc gcgtcctcga tggactcgac gccctcggcg aggactgcga
      961 gggcggacgg cacaccccgc gattccggcg cgtcctcggc cgaggccagg ccgtcctcca
     1021 aggacgtccg gcccggccgg gtcaggtagg agacctcgac cagcatcgcc gcgtcgcgtg
     1081 cctgctcgta ggtctcggcg accacgaagc cgatcggctg gccgtagtag gtgacttcct
     1141 tgtcctgcaa aggcacccag gtctcgccca tgaacggcgt gctcggagtc cgcagttcca
     1201 gcggctcgaa gggcgtgtac acgccgatca cgccgggcgc gcccctcgcc gccgtgacgt
     1261 ccatcgtgtc gatctcgccg tgggcgatcg tgctgagcac gacgtaaccg tggaccagtc
     1321 cggggaaggt atggtccgcc ccgtactcgg cccggccggt gaccttcagc ggcccgtcca
     1381 ccctgctgct catgagcggc tcccctcggt cagttcgagc agcgcgcgga cgatggtccg
     1441 ccgcagcaac gacggcttga atccgttcgc ggccaacggg cgcgctccct cggcggcgag
     1501 cgccgcggcg tcttcgaagg cggcgaccgt cgcgggcgca ccccgcaagg cctcctcgac
     1561 cgcgggcagc cgccatggca cggtggcgac gccgccggcc gcgacccggg cgtcgacgac
     1621 gcgcgagcct tccacccgca gcgcgaccgc cgcggagcac aacgcgaact cgtaggactg
     1681 cctgtcccgc accttgacgt aggtggagtt cgacgcccag tccagccgcg ggaccacgac
     1741 ctcggcgatc agttcgccgg gccgcagatc gttctcgacc tcgggagtgt cgccgggcgg
     1801 gcgatagaag gagcccagct cgacggtgcg gctccctgcc tcgctgacca ggcgcagccg
     1861 cgcgtcgagg gcgaccaagg cgacggccac gtcgctggcg tgggtcgcca cgcacgaatc
     1921 gctcgtgccc agcaccgcgt gcatccggtt ggcgcccgaa atcgccgggc agccgctgcc
     1981 gggaacccgc cggttgcacg gcatggcgac gtcgcggaag tacgagcagc gcgtgcgctg
     2041 catgagattg ccgccaatgc tcgccatgtt ccggatctgc tgtgaggcgc tgagcagcag
     2101 tgcacgggag atcgccgggt acaccctggg atgcccggcg atgtccgcca tccgctccag
     2161 cgcgccgaaa cggagcccgt cggtggtgtc gatgccccgc agcggtaccg cgttgatgtc
     2221 cagaacctgc tgcggtgtca ggacattgag tttcatcagg tcgacgagcg tggttccgcc
     2281 cgccaggaac gtgccggacg agccgaccgc gtcttcgacg gtctcggggg cgagcagctc
     2341 aaagggacgc atcggccctc ctcgcctgct cgaccgcggc gacgatgttc ggatacgccg
     2401 cgcatcggca gagattgccg gacatgaact cgcggacgtc ctcgacgcct tgctcgatgg
     2461 cggcgacggc cgacatgatc tgcccggacg tgcagaatcc gcactgcagg gcgtcccgat
     2521 cgacgaacgc ctgctgaacc ggatgcaaac catcctctgt ggacagtgct tcgaccgtgg
     2581 tcaccggctg cttcacggtg gccgccaggg tcaagcagga gagcaccggc cgtccgccga
     2641 cgtgcaccgt gcaggcgccg cactgccctc tgtcacagcc cttcttcggg ccggtgacgg
     2701 cgagccgctc ccgcagcgcg tccagcaggg tcaccccggg atcgacaccg agatgttccg
     2761 tcctgccatt gacttcgagt gagatgtcca ctggatctct ttccgcagat cgtccgggcc
     2821 ggggcccgac ggcgtaggtt gaggtggtgg ggagtctgtt cgcgagacga aacggatatt
     2881 catccgcttc gattttcaag ttagcggaat acaatccgct cggcaaggtc gatgctcgcc
     2941 ctggagtcgc tccaggtccg acgggttcct cggctacatt caccggagga cgggtcggcg
     3001 gacaggaggg accatgacga cgggatcggt caatccccgg cgcgcggaca cccgccgcaa
     3061 ccacgagcgc atcctcgcca ccgcggcgaa gtcgctggct tgttccggcg aggtttcctt
     3121 caatgccata gcgaaggagg ccgaggtcgg cgtcggcacg gtgtaccggc acttccccac
     3181 gccggaggcc ctcatcctgg cggtgtaccg gcgtgaggtg cgtcagctcg tcgagatcgt
     3241 gccgagcctg ctcgagaagt atccgccgga acaggcgttc cgcgtgtgga cgaccgacca
     3301 cctggcgcac tacatgatga ccaaacgcgg tcttgccgac gctctgcgcg ccgcgaccgc
     3361 cgcacgcggc gagctgcccg cgggggccta ccaggacatg gtcggcgcgg tctccaccct
     3421 gctgcaagcc aacatcgacg ccggcaccgt ccgcgcgggc ctggcgccgg aaaccgtcct
     3481 gcgaggactg ggtggactgc tctatctcga cccgaaaggc gaatggcggc gtgacgtcgc
     3541 gagcctgctc gacctgctgt ggcacggaat gggcaccggc ccggcccgaa catccacagt
     3601 ggactgagtc agccgggcac tggcacgccg ccgcgcagat agtccaggta cagatcgagt
     3661 gccgcttcga ggtggtccgc ggatccggtg gacatcagta tcgtcacccc gccctggatc
     3721 gcggcgatca gtgctgccga ggcgcgcacc gggtcgacgt cacgagcgat gtcaccgctt
     3781 tcccgcatgt cctcgatgcc ggcctggacc tgacgttgcc attgctccag cagctgcctc
     3841 gtgaccgctt gagcggccgg ggtgtgcctg ccgatctcgg tgatcagcac cccgagcgga
     3901 cagtgcaccc cctgccgtcg gtagcgccgg atcaccacgt cacgccactt ctcccacgcc
     3961 tcccacgtgg tcaaccgacc gaggtagggc tgctgatcct caatgacccg cccggcctcc
     4021 cattcggcca cggcgaggag cagctcttcc ttgccctccg ggaagtagtg gaacagctga
     4081 ctcttgcccg ttccgctgcg gcgacagatg tcgtcgaggg tcgcggcccc cacgccgtgg
     4141 tcacggatct cgtccgccgc ggcttcgatg atccgctgcc gcgtcgcggc gcccttcttc
     4201 gtgagcacga aagcctcccg gaatgtactc ggcggtccat tgtgccgtgt ccgctccgca
     4261 ccgcggtcac ggcatcagta gcagctttcc cgaggtgcga cgggattcga tgtcccggtg
     4321 cgcacgcgcc gcgtcggcga gggcgtagcg gccgccgata aacggggcca cctgcccctt
     4381 tcggatgaac tcgaacagct cgtccgttcg ccgcaccaac gcctcacggg tgggcacgtg
     4441 gtcgacgacg gacggatagg acagcaggat gctgctcggc aggtccgcgg gacggaacac
     4501 gggatttccg ttcaccacgc cgtagtaggc gtgcacgccg tggcggcgca gcgacagctg
     4561 ggacgagtgg aacgtcgccg agccgccacc gtcgtacacg acctgtgccc cctcgccgcc
     4621 ggtcagctct cggacctgtc gttcgaagcc gctcccggtg gacaccagca catggtccgc
     4681 gccggccttc ttcgccaccg ggatcttctc ctcgcgtgac accagcccga tcacggtgcc
     4741 gccgcgagcc ttgatcagct gggtcaggat ggtcccgacc ccccgcggcc gagtgcacca
     4801 cggccgtgtc ccccggcttg atcgcgtacg tctccgtcgt gaaatggttc gcggtcaagc
     4861 cctgcatcag gacggcggcc gcggtctcgt cgtcgatgtc atcgggcacc cgcaccagcg
     4921 acgccgccgg gatggcgagc cgttcggcgt agctgccctt gtggtagcgc caagcgaccc
     4981 ggtcgccgac ggcgaagtct tcgacgcccg gccccagcgc cgcgacgacg cccatccctt
     5041 cgacacccag cacggtgggg accgaccagg tgggcagcgg catcttgcgg gcaccggtgt
     5101 ccatgaagtt caccccggcc accttcagtc gcacgccgac ctcgccgggg cgcggcaccg
     5161 ggtccgggaa ctcggtccag gtcatgacct ccgggccgcc gtattcgctg atgtgaatcg
     5221 cgtgcatgag gccaacgtag gtccgaaaaa atgtaccggc aagtacagaa cctggcgcgc
     5281 aggactgtac ttgccggtac attttttcgt cggcattctc ggccgggtca acctcaccga
     5341 acgaaggaag ccgatggacg acctcacccg gctggtggcg gtggaggacg tgcgacgcgt
     5401 gatggcgcgc tacgtctaca gcgccgacca tcatcgatgg gacgacctcg ccgccctgtt
     5461 cacgcccgac gctccgttcc tcgcctccac agtggacgga tcgacccaag cgcgcatgac
     5521 cggccgcgac gagatcgccg ggcggctcaa agcccgcaac caagccgatt ccgtgctggt
     5581 acatcacctg ttctccagcg agatcgacat cgagtcaccg gattcggcgg ccggtgtctg
     5641 ggccatggag gacatcgtca ccacgccgca cgacggcgaa atgcacggtt acggccatta
     5701 ccgggtgcgc ttcacccgat cggacggccg ctggctcatc gccgaacttc gcatcaccag
     5761 gcttcgcctg gactggaccc acccggacaa ggaaaaccga ccatgacact cgaaccgttc
     5821 gtgatcgacg tcgaacagga cgtcctcgac gacctccggc ggcggctgaa agcgaccagg
     5881 ttcgcacccg acctggacaa cgaagacgag gctttcgggc tgagtaccgc ctatctcaag
     5941 ccgatcgtgg agtactgggc cgacggtttc gactggcgag ccgtcgaagc ccggttgaac
     6001 gagtactcgc accatcgcgt cgaggtcgac ggcaccccgg tgcacttcat ccgcgagccg
     6061 gggaagggtc ccgcgccgat tccgttgctg ctcatgcacg gctggccgtg gaccttctgg
     6121 gactggagca aggtcatccg accgctcgcc gaccccgccg cgcacggcgg tgaccccgcg
     6181 gacgccttcg acgtcatcgt cccttcgctg cccggcttcg cgttctcgac tccgctgacg
     6241 aacggcaagg agaacttcgt cagcatggcc gaccggttcc acacgctgat gaccgatgtg
     6301 ctcggccatc ggcgattcgg ggtcggcgcg gccgattacg gagcgctggt cggggcgcaa
     6361 ctcggccaca agtacgccgc ctcgctccac gggctccacc tcggcaacga gatgccgctg
     6421 acgatcttcc agggcgcgcg ccactgggat ctcaccggcg gcgcgccggt cgacgacctg
     6481 cccgcgggcc cgcgcgccga catggtcaac ttcgtcgaca cctacgtttc ccatgtcgcg
     6541 acgcatatgc tcgacgcgca gacgatcacg cacggcctga acgattcccc gatcgggatg
     6601 ctcgcgtgga tcctcaagcg gtggaagaag tggagcgacc agaacggggt cttcgaagat
     6661 tcctatccgc tggaccacat cctcaccaac gcgacgatct actgggtcaa ccaggccatc
     6721 ggctcgtcga tccgcgccta caagaacgtc aaccgccatc cgtggcggcc gtcgcacgac
     6781 cgcaccccgg cggtcgaggc gccgaccggg ttcaccttcc acctcggcga cgccgcgccg
     6841 ccgggagccc acgaccgcga acgtcgcatc gccgcgttca aggaagcggc cggtcctgtc
     6901 tacgccgacg tgcggcaggt gaacgtccac gaaaagggcg gccatttcgg gccgtgggaa
     6961 catccggaag cgtggatcga agacctgcgc gccacgttcc gcccgctgcg ctgagcgagc
     7021 ggcctcacag ccgggggatg ttgcggaggt tggcccgggc gaggtcgatc atccggccga
     7081 ccccgccttc gaggacgacc ttgctcgcgg ccaaggcgaa cccaccgagc tgaccggcgg
     7141 tgatatgtgg cgggacggac agcgcgttcg ggtcggtcac gacgtccacc agcgccgggc
     7201 cgtcgtgact cagcgcttcc ttgagggccg cgcgcaaccg ggtcggatcg gtcacccgct
     7261 cggcgcgcag ccccgcgcca ctggcgatgg cggcgaaatc gaccggacgg tggtcggtct
     7321 gatagtcggg caggccgtcc accagcatct ccagcttcac catgcccagc gaggaattgt
     7381 tgaacgtcac gatcttgacc ggaagatcgt gcaaggcgac ggtgagcagt tcgccgagca
     7441 gcatgcccag cccgccgtcg ccggacatcg acacgacctg ccgtcccgga taggcgaact
     7501 gcgcgccgat ggcgtgcggc agggcgttgg ccatcgtgcc gtgcaggaac gacccgatga
     7561 cccggcggcg cccgttgggg gtgagatacc tggccgccca cacgttgcac atgccggtgt
     7621 cgacggtgaa gatcgcgtcg tccgcggcga gttcgtcgag gagatccgcg gcgaactccg
     7681 gatggatggg cacgtgccgc tcgacgttgc gggtgtaggc gtcgacgacc tgctccagcg
     7741 ttttgcagtg atcacgcaac atgcggtcca ggaacgtgcg gtcggtcttg cggcgcagga
     7801 gcggctgcac ggcccgcagg gtctcccgaa cgtcgccgtg caccgccagt tcgagcgggg
     7861 tgcggcggcc gagccgggtc gcgtcgtggt cgacctgcac ggtccgtgcc tgcggcagga
     7921 aggagtcgta agggaaatcg gtgccgagca agaccagcag atccgcgtcc tgcatggccc
     7981 ggtagcaggc gccgtagccg agcagcccgc tcatcccgac gtcgtaggga ttgtcgtact
     8041 ggatccattc cttgccgcgc aggctgtggc cgaccggtgc ctgcacggtc ccggccagct
     8101 ccatcacctc cgcgtgggca ccacgcaccc cggcgccggc gaacaaggtg acggtctcgg
     8161 cgtcgttgat caactcggcg agccgggtca cctgcgcctc gggtggcacg atcgtcccgt
     8221 gctcggtgac cggcgctccg gatccggtgg gcgcgacagc gtcgagatgc gcgacgtcgc
     8281 cgggcagcac cagtaccgaa acctcgccgc gggacaccgc gtgctgcatg gcgatccgca
     8341 gcaccctcgg catctgagcg ggcccgctga tctgttcgca atatccactg cagtcgacga
     8401 acaaccgttc gggatgggtc tcctggaaga acccggtccc gatctggccg gacgggatgt
     8461 gcgaagcgag cgcgagcacc ggggcgccgg tgcggtgcgc gtcgtagagc ccttgcacca
     8521 gatgggtgtt gccgggaccg cagctacccg cgcacaccgc gagccgcccg gtcagctggg
     8581 cctcggcggc cgcggcgaaa gcacccgcct cctcgttacg gacatggacc cattcgatcc
     8641 ccggggtgcg gcggatcgcg tcgacgacgg ggttcaggct gtccccgacc acgccgtaga
     8701 tccgttccac cccggcctgc accaggactt ggacgaactg ctcggcgacg ttgggcttgg
     8761 ccatcacgac cccttcgatg cttcggcggc ggaataccct catgatccac gtgcgggcac
     8821 cacctcgcag gtcctggtga ggggtaaggc gaatatggcc tgatcgaggc cgcggcggga
     8881 gcgggctcac cgaggaccga gcacgaccgc cggtcggaaa ccgagtgacg cgaaagccac
     8941 tttcgggaca ccagacgtcg cgaaagtggc tttcgcgacg tcagttccgc gcgggggtcg
     9001 tgagtggcaa agagcgttag aacgacactt accactcacg acccgcccga tgccggccgt
     9061 acgtacctcg aaggcacgcc cggtcctagc cgagttcggc cgaggaaccg acgacgacgg
     9121 cgtagaggtc accgatcgtg gcgagcgccg cgcggtgctg gtccgcggcg gtcaccggac
     9181 cggcgacaga gggaagcgcg cgcgtcgcgc aggccccggc cacgacggtc ggggcgtttc
     9241 cgcgcaggaa cgcgccctcc gcggtgaacg tgacgcacat atgggtcatg aacccggcca
     9301 cgacgacgtt ctggtgcccg gcggcatcga ccagctcgcc cagccgggtc ccgacgaacg
     9361 agttcggcgc ggtcttcacc acgatctcct cacccggacc gggggcgaca cgctcgtgga
     9421 tccggccgat gtcctggccg aggtcgtacg ggctgccctc gccgccgtcg tgcatgacgt
     9481 ggatgaccgt cgccccctcg gcacgagcgc gcgccagcaa ggtggccgcc tcgtcgagcg
     9541 cggcttccca gccgtcgagt tccatcacgc cgcgcgtgta ggtgttctgg tagtcgacga
     9601 ggatcacggt cgcgtccgag agcgtcgcgg gggtcgtcgg caacgtactg atttcgcgga
     9661 gggtggtgct ggtcatcgtg tgttccttca ctttccggtc ggtacggtta cccatgatcg
     9721 ttgacccgat ccgatagtga gatacggttt cgggtcagcc gtggtcgaca tcggccgaca
     9781 tccgcgggaa gggatcgatg aacgctccga gtgtggccgt cctgacgttc gaagggatca
     9841 acccgttcca tctcgccgtg ccgtcactgg tgtggggccc tgaatccccg gcaggtgaca
     9901 tggagccgtg gccgatcacg gtcgccgccg tcaccccggg caggctcacc acgagtgccg
     9961 gctattcgat cgacgttccc gccgggctcg gcgcgctcgc ggaggccgac atcgtcgtcg
    10021 tcccgtggtg gtccgacccg gaatccccga cgcccgcgcc cgttgccgcc gcgctgcgag
    10081 gcgcgcacga acgcggagca ctcgtcgtcg gactctgtct cggggtgttc gccctcgcgg
    10141 acgccggcat cctcgacggc cgcaccgcga ccacccactg gaaatgggtc gaaaccttcc
    10201 ggaggcgctt cccttcggtg cggctgcgtc cggaagagct gtacgtcgac gaaggcgaca
    10261 tcgtgaccgg cgcgggcgcg accgccggga tcgacacctg tctccacctg ctcgcccgca
    10321 cggccggaca ggtcgccgcc aaccgggtcg cgcgccggat cgtcgccgca ccgcaccgtc
    10381 ccggcggcca ggcccagttc atcgagcttc ccgtaccgga gaaggacgac gacccgctca
    10441 ccaccgtgat gaactgggcg cggtcccatc cggacgtgcc gcatggcatc gacgatctcg
    10501 ccgcccgggc acatatgagc cggagcacct tcacccgctc gttccgcgcc cgcaccgggg
    10561 ccaccgtcca cagctggctt gtcgcgcaac gcctcgcgcg ggcacgccac cttctcgaga
    10621 cgaccgcgct cggcatcgac gcggtcgccg cgcagtcggg gttcggcacg gctgcacgcc
    10681 ttcgcgagca cttcgccacc gcgctgggca cgacgccgac acgctaccgg gtggaattct
    10741 ccgcagggaa atccttttcc cccagctgac gggaaagtgg aatcattatt tccgcaaacc
    10801 ggcggaccgc agtgcgagca cggaattgac catgtcctgg actcgtcttt tcacctcgcc
    10861 gaatggctca ccccggaggg tgagctctat cgagtgcatt gcccggcgga actggatcga
    10921 agaagccgcc gcgaggcaag atgatcgggc acgaagcccg gcgcgacgga ggaccatgtg
    10981 gagcagtgcg gaacccccat cttcgactct ctggtcgagg aggcaaggaa ggcggccgcc
    11041 ggaaatgaca tgctcccccg cgagtacgat tccgaatcga gcgagccgcg tacggatgac
    11101 gacaagggaa acaaatgacg atcaccggac gcgatgaccg agagaaatgg ccgttgtcga
    11161 ttttcagtct gtttccgatg aatgcgcgcc accggaaacg ccggtggaat tctgcagatc
    11221 gtcgagcaga cccaactggc cggtgatgag cccggtcagg atcccgcgag tgacggcgag
    11281 cagttcggcg accgacggac tggtcagcga ataggagacg gtcgtaccct ccttgcgcgg
    11341 caccaccaga ttggcacgac gcaggacggc gagctgctga gacaggttgg cgggctcgat
    11401 accgaggtcg gcgagcagct ccgagacatg gtgctcccgc tcgctgagca gttcgagcac
    11461 gcggatccgg acggggtgcc ccagcgtctt gaagaactcc gccgtcgcct gatacagggg
    11521 gctgttcatc ggcatccctt ccccgcaggt ccggccgtcc acacgaacct gatcgtgccc
    11581 gattcgcgga accgccggac ctcaccccgc cctgatcggg tgcgaccaca cacgatcagg
    11641 gcacaaaatc acggtgattc gacagcgcac gcccatgaat tgcatattta tgcaagtctg
    11701 catatcagag aaaggtgaga acacctgtga gtcacggcat gcgggattcc gcgagcctct
    11761 tgtcgatcct ccggcccgcc acgaggagtg gacggtgacc acacgccatt ccctccccgc
    11821 cgccgccacc cgggctcacc tggtcctcgc cgcgcacgcg gcggaattgg ccgatctcgc
    11881 cgcgaacgcc gcccgagtgg acgccacagg ggaacaggac acgggctcga cgcgggatcg
    11941 ttccagtctg atcgaaatgg cgcagcagat cctcgaggcg gcggtggtgg ccgcgcgact
    12001 cgacgggaag acgtgggagg agatcgcgtg cgggctcgac ggggcgacac cgcgctccgt
    12061 ccggaccagg tactggcctt cggtcgcgcg attccgcgcg gatcccttcc cgtcgcagga
    12121 cgcgcgccac gagaacatgg cggagcacac cgaacagacg gccttccgcc tgcgccggct
    12181 gccgaccccg gaccggcgac ccgaagccga gtccacgacg gggccgaccc cgcacctcgc
    12241 cttggtcacc gtcccggccg aacagggcga cggcgaagcg gtgcgtgaac cggcggccgc
    12301 ggacgcccgg ctgaagatcg cggaacggct ggtcgcggcc tacgagcgga tcgcgaccaa
    12361 cgaccgccgg cccccgcaat ggatcctcga cggcctggcc cacgcccgtc acacggccgc
    12421 ggcactccgt gcccacgcgg gcacgccgcc cgaatgactc tcggcgggaa gctacaccgg
    12481 ggtcgcgaga ccggcttcgc ggtcgaagtc gtgctcgtcc tcggtcttcg tccgcgccac
    12541 catcttcgcg accaggtcga agatcggcgt ggcctcctgc gggaaggtca cgctctgctg
    12601 gttcgcgctc tcggcgatca tgaaccgcta ctcctcaagg gtgatgacta cagcgaccgt
    12661 tcactctaac ggtcccgtcg gcggtgacgg gacgtattcg gagttttcgg tcgaacctca
    12721 ccccgggcgc ccgaaacgca aacgggctca ggaacctttt gcggaaatac gatcggcggc
    12781 cacctcgcgc tcacgcctgg tgagcaccag cggagcgcct tcggtgatgg cgaccgtgtg
    12841 ctcggaatgg gccgcacgcg agccgtcggc cgagcggatg gtccagccgt cgtcgtcgaa
    12901 gacgatccgg tcggtcgtac gggcgaacca gggttcgagc gcgacggtga gtccgggctg
    12961 gagcttcagg ccgcggcccg ccttgccctt gttcggaatg tgcagctcct cgtgcatggt
    13021 gcggccgatg ccgtggccgc cgaactcggt gttcaccgga tagccgtggg cacgggccac
    13081 cgcccagatg gccgcggaga tgtcgccgag gcggttgccc ggacgcgcgg cctcgatcgc
    13141 ggcctccagt gcctcctcgg tggcgcggac gatccgcagg tcttcctcgg cgggcgtccc
    13201 gacgatgacc gtgcgcgccg agtcggccgc ccagccgtcg atcttcaccg cgagatccgc
    13261 ggtgagcacg tctccgtcgt gcagcgtgta gtcgtggggc aggccgtgca ggacggcatc
    13321 attgaccgcc aggcagatca cgttgcggaa cgggcctttg ccgaaggacg gcgcgtagtc
    13381 ccagtagcac gactccgcgc cgcgacgttc gatcatgccg cgcacgtggt gctccaggtc
    13441 catcaggttg acgcccacgt ccgcgaggtc gccgacctcg gtgagcactt cggcgacgaa
    13501 acgcccggtc acctgcatac gctcgatctc ggcgggcgtc ttcagttcga tcatcggatc
    13561 ctcgcgtccc tggttggtat tattataccg gcaccctagc aggaagcggt ataataatac
    13621 caatcagtgg ggcttactgc gccggatgac agcgctcgat cgcgtcgagc aggatcccgc
    13681 acgcgagctc gatctcctcc gcggtcacgg tgagcggtgg catcaggcgg atcacgccgt
    13741 cgtcgcggcc accgagttcg acgatcaggc cgtgccgcag cgcgtgagcc tgtacggccc
    13801 gggcgtatcc gcccgccggg cggccgtcgc gcggatcggc cagctcgatc ccccacatca
    13861 ggccgaggcc acgaacctca cggacccaga cgtgatcgtg caggacgccg agtcgtcgag
    13921 cgagctgcct cccgcgctgc cggacattgc ccagcacgtc gtcccgccgg acgacgtgga
    13981 ccgccgccgc gccggcggcg aacgcggcct gattgccccg gaacgtgccg ctgtgcgcgc
    14041 cgggcgccca gccgtcgagc cgccggtcgt agaagatcat cgccaccgga agccccattc
    14101 cgctcaaggc cttcgaagcg atgatcacgt cgggctcgat gtcgtaatgc tcgaacgcga
    14161 accaggttcc ggtgcgaccg catcccgtct gcacctcgtc gacgacgagc gggatgtcca
    14221 gttccgcggt cagcgcgcgg acgcgccgca cgaaatcgcg gtccgccgga atgatcccgc
    14281 cttcgccttg caccatttcc aggatcaccg cggcgggaag ggggatgccg ccgttgggat
    14341 ctcgcagcga ccgttccagc aggcccacgc agttggtctc gcacgtgtcc ggcgaaaggc
    14401 ccaccgggca tcgagcgcag tacgagtacg ggaagaagtg cacgccgggc acaccgttgg
    14461 cgatcggccg tttctgggcg acgaggccgg tcaacgccat cgcggcgtgg ctcgagccgt
    14521 ggaacccgcc ctggaaggac accaggtcac cacgcccggt cgcggtcttg cagagtttga
    14581 tcgcggcgtc gacggcgttg gccccgccgg gaccgcagaa gtgcatccgt gtccgcgagc
    14641 gcaggccggg cggcagcatg gaaagctgag cgtcgatgaa ttcgcgtttc gccggtgtcg
    14701 ggaagtccag gccgtgggtg agcacggtga gttgttcggt ggccgcccgc accagttcgg
    14761 gatggttgtg gccgagggag agcacacccg cgcccgagag gaagtcgagg aagacgttcc
    14821 cgtccatgtc ccacaggtgg cttcccgccg cgcccgcgat cgctatcggg aggtggcgcg
    14881 ggtaggcccg cgcgctggac tcccactggc gctggtgttc gaggtactcc gccgagcgcg
    14941 gccccggcag tgcgccttcg acgcgaggca ccagggccgg cctcgccgtg ggggtgggga
    15001 tcatggcaac ctcctggtcg cggcgatctc atctgccgtg tcgagttcga ccgccgggtt
    15061 ggcgtgccag cgggttcgcg ccgggaccgc ggtgcccttc atcaggaacg cgtcggcctc
    15121 ggcgatcgct ccatccgcca tcgtcactcc atagtggacg aaggcgccga cgccgagcgt
    15181 gcatcccgcg ccgatggtga tgtggtcgga tttgaaggtc ccgtcctcga gcgaatgtcc
    15241 ttgcgcgacg gtgtgcaggt tgagcacgca gtcgtcgccg atgctcacca gggaccgttc
    15301 cgggatcgcg cagccgtcgt cgaagacacg ccggccgatc cggacgccga gacggcgcag
    15361 gaggaacggc ttgaacggtg tcccgttgaa caacgcgagg tagcgggcgg gactgagctt
    15421 ccagaaccgt tcgtgccgcc agaaggccgg gtcgtagatc gagcagaaca gtggccgcat
    15481 cgcccggaag ccctgtacgg ccagttccgc cagcatgagg aacgcgaccg agaacgccag
    15541 cgtcgcgacg atgccgccgc cgacggccag tgggccgagc cgcccgtgca gggcaccggc
    15601 caccgcgccg atcagcagga caccgaacag gtgcagccag tgcacgagca ggtaaacgcc
    15661 gatggtgacg gtgttgtgcc ggttcttcgc ccgtaagccc cggcgcagcg cgtccccggt
    15721 gccgaggtgc tcgaacccgg tgtcacggcg gacagtgcgg ggtatctcga acgcgggcga
    15781 tcccagcagg ccgacgttct cccggaccgg tccgtcgagg ggaacgagga ccttggtggc
    15841 cagcaggcag ttccggccga tcctcgcgcc cggcgggaag gcgatctcgt tgccgaggaa
    15901 ggcctgcggc gcgacggacg tcttgcggag ccggaacgac gatgcggaga agtcggcgtt
    15961 gagcagcgaa aggccgtccg agaccatcgt cccggtgccg accgtgctga ggaacggcgt
    16021 ctcgtgtttg acctcgaccc cgaagttcga tccggtctgg tggaccttcg acaggtcgta
    16081 tcccagcgcg cgcaggtagt acacgatgta gctgctgtcg ccgaacaggt acgtgtacgc
    16141 gcgcaggttg gtcagccgcg cgatcagtcg ctggatcgcg aaatgcctgc cgtagagcgg
    16201 gtagacgtgg tccggccgga ggaacaggcc gagcaggcgc gggagcacga ggacgaccgc
    16261 cagtccggcg agcagcgcac cgaagtacac cagtgccgag tcggcgatcc ggccgagata
    16321 gaaggcccag ctcgtgaagt ccaccgtcgt cgtgaaccac tgctcgacga gcacaccggc
    16381 accgcccagg ctcaggggaa gcgtgccgag cagcagaagc agcaggctgg acgcgcagaa
    16441 gacgatcggc ctgagcctgc cgcgcgcgac cgtgcccagc gcccggtagt ccacggtgga
    16501 caagcgagcg ggagacccgt gccagctctc gccgtcgggg acggactggc cggagtgcaa
    16561 ggacgacgag tggccgagct gtgcgccgtc gccgagcgcc gagccgatgt cgagcacggt
    16621 catttcaccg acgaaggcgt tggcgccgag cgtgaccgtg ccggtctgga tccggcccgc
    16681 cctggcgcgg tagcaagaga agtaggcgtc cttccggatg acggcgccgg caccgacgct
    16741 gagcagatcg gtgcagaccg gcgggttcct ggacaggatc agggcgccct tgccgatgtc
    16801 cgcgccgagt gcccgcagat accacgagta gagcggagtg ccgacgaaca gcatcagcgg
    16861 gctgaatctg accagggcct tgaccgtcca gaagcgcagg tagccgacgc tccacagcgg
    16921 gatctccccc ggcttccacc ggccgacgag catccacttc gccaagaccg gcaccacgga
    16981 gagaacgacg aacacgacga acccgagccc ggcggcgcgc gcgtagcttt cggcgaaccc
    17041 tgtcgcggcg tcgatccagc gaaatcctgt gtccaggagc cagcccgaac cggcggcata
    17101 ggcgaggaag gccaggagct ggaacactcc acaaaggaca tacgacgtag tggacgcccg
    17161 gcgtggctcc tcggcccggg cgaccgtggc ctcgaccgcg gaggcggtcg actcggcgag
    17221 gccgcggatg gtgggattga ggtacacgtc cctggccgac agcgacgcga cctcgccacg
    17281 ttcccggacc accgcacaga acttggccag cagcagggag tcggcaccgt agtcgtcgaa
    17341 gaagtgcccc gtcaccgaga ccggctcgat cccgaggaca ccgctcaagg cctccgccag
    17401 gcgcagttcg gtcttcgtcg cgggcgccac gtagtcgacg tcgttgccca cccttcgtgg
    17461 gctcgagggt gccgggagat gcttgcggtc ggcttttccc gccggtgtca acgggatgtg
    17521 gtcgagttgt tcgaggtagg cgggcaccat gtagcccggc agcagttccg ccagccggcg
    17581 gcgtagttct ccgggatcga cgtcctcgtt gtcgcgccgc aggctgtagt aggcgaccag
    17641 ttcggtggtg cccgcttccg gatggtgggt ttcgaccacc gcctgggcga ttccggggat
    17701 ccgcaggagg acggactcga tctcggtgag ctccacgcgg tagccgcgga tcttcacctg
    17761 ggtgtcggcg cggccgtggt attcgatctc cccgtccggg gtgatccgcc ccagatcgcc
    17821 ggtgcggtag atccggcggg acggattgtg cccgatgccg aggaagtccg ggatgaacgc
    17881 gcgttcggtc agatcgggcc ggttcaggta gccacccgcg agtccgatcc ccgcgatgcc
    17941 gatctccccc agttcgcccg cggccagcgc caccggctcg tccggatcga ggatgacgac
    18001 cgaataggtg ggcaggggca ccccgatggt caccggccga tcgggtcgca gcaccgacca
    18061 ggtcgcggtg accgtggcct cggtcggacc gtagacgttg aggaatctcc ggtccgcgcg
    18121 ataccagcgg cgcacgaggt cttcgggaca cgcttcgccg gacaccagga ggaaccgcag
    18181 cagcggcagg tcttcgtcga ggctggccag cagggtcggg acgcagcaca acgcggtgac
    18241 ccggttctcc cgcaggaatt cgaggagatc gtgcccgacg agggcggcac cgccgggttt
    18301 cggcacgagt gtcgcgccgc tcagcaacgg cacccagatc tcctcgaccg agaagtcgaa
    18361 cgcgatcgtc atgccctggt agacccggtc ggtgtcctgg atgccgtaga cgtcggcggc
    18421 gaccaggacg aagttgcaga tcgaggcgtg gtcgatcgtc acgcctttcg gccgcccggt
    18481 cgacccggag gtgtagacga cgtaacagag ttcgtcggca ggagtgcccc tctcgtccgc
    18541 gctgagccgg gttcccggca gtgcggcgat ccggtccgag tcgacgtcga ggcagacgag
    18601 gtcgacagcg tccggctcga accgttcgcg cagcccggag gtcgagatca cgagccgaac
    18661 accggcgtcc tggacgatgt aggccaggcg gtcgtcaggg aaacccgcgt ccagcggcac
    18721 atacgccgcg ttgaccttga gcacggcgag catcgcgacg tagggatgca ccggttcggt
    18781 gaacagcagc ccgatccggt caccgggccg caccccgtgc gccagcaggt gccgggcgag
    18841 ccgattggcc cgctcgtcca gcccaccgaa cgtgaccttc actcctcccg cgtccactgc
    18901 caggcggtct ccgagcccgg tgtcgcgcaa gcggtcgcag agccgctcgt acaaccgctc
    18961 cagccgatca ccggtccgcc atcgaacccg ctgctcgtgg ccgtcgcagg tcagtaccag
    19021 gccgtcggtg gtgaactgcc ccgacggctg tccatacggg ctcatgcccc gtcctccgcc
    19081 aacccgaagg agtcgtgcag ggctcggacg gtcgtgtcga cgacgtcggc ggggaccacc
    19141 gcggtgaggc gcgatcgcga cgtcgtcatg gcaggcaccg tgaccctgtg gccggcgagg
    19201 atccgcagca actcgggcag aaacccgggt ggatcgagca gcgcggtgcc gaccacggat
    19261 acggagccga gttcttcgca gaccgtggag cgggcctcca gttccatcgc gagccgggtg
    19321 atcggcgggc cgagcggctc cgtcccgcgg acggtgaacc tcagttctcc gggatcgggc
    19381 cagctcaggt tgtccggtcg cactccgcag tccgccagca tcgcgagtac gcgtgcgtaa
    19441 cgatcggggt ccgaggccga aacctcgacc cggaccagtc gcacgtcgcg ttcgtgggcg
    19501 attccgatga cgcggggtgt gtcttccagc ggctcttctc ccgccttgac gacggtggaa
    19561 ggaccgggat ccgacgagtg cttcacccgc accgccaccc cgtggcggcg cgcgagatcg
    19621 acggatctgg gatgcaggac gcgggcgccg accccggcga gctcggccat ggcgtcgtag
    19681 gagatcgtcc ggacgggccg ggtgtcccgc acgatccggg ggtcggccgt gcgcacgccg
    19741 tggacgtcgg tgcggatctc gcattcggtg ccaccgagcg cggccgccag tgccaccgcg
    19801 gtggtgtcgg agccgcctct gcccaaggtc agcagttcac cgtcggcgtt ccgtccctgg
    19861 aatccggcga ccacgacgac ctgcgcgtcc cgcagccgcg cgacgatcct gccgggatcg
    19921 acgctcacga tggtgcccga tcccggttca cccgcgacct cgattcccgc ctggtcaccc
    19981 gacagcgaga cggcttcgac cccgcgctcg gtcagcgcca tggcgagcat cgcggcggac
    20041 gcctgttcgc cggtcgccat caactggtcg agttcccggg gagcgggtgg ttcggcgacc
    20101 tcgcctgcca gcgcgatcag ccggtcggtg ctgtccccca tcgccgacac gacgaggacc
    20161 acccgatccc ccgtcgcggc gatcgccgcc acctcggcgg ccacctgatt caccattgcc
    20221 ggggtggcca gggacgagcc accgtatttt cgtatgacga gtgcttcgct tcgtgaatta
    20281 cgtaaagccg agtccgggct gacatcgagt ttcggggaaa aattcaccat tttccttcat
    20341 gaggtcgccg caaatggccg cattcgcggc agggcatacg acagggtccg gggctccctg
    20401 cccgacgaga cgacttggca gggatgacag gtttggaaag tagtgcggga cgcattccac
    20461 gggtacctcc ataagtacga aacctcgacc gcccgtttct cgcaggccat aacccggcga
    20521 cagtgcgcgg cgttatgacg gcaaacagac gagttcgatg gaattagggc agaagaatga
    20581 caaattcgca gagtcttcga aattcgggaa aacctcgtca tgacaaaacg gaacgaattt
    20641 ccccactcgc cgggcattac gagatccttt tacccgccca gctccgggag aaatctgtca
    20701 aaatggccgt ggcgtgccca ggaccgaaat ccgggcattc ttcccgttga tcggaaagcg
    20761 gacatgaatg tccgtccttt gtggaggatc gtcagccgac cggagaggga ctgcccagcc
    20821 gtccgtcgtg cacctcgacg atccggtcca ccgcggcgag atggacgcgg tcgtgcgtga
    20881 ccaggacggt ggcggtggcc cgctcgcggg tcaggccggc gatcaggtcg acgaccgccg
    20941 cgccgcgctc gtgatcgagg gcgctcgtcg gttcgtcgat cagcagcacg gtgggttcgt
    21001 tcatcaacgc gcgcgcgatg ttcacgcgct gccgttggcc gccggagagc tggtgcggac
    21061 ggcgtcccgc ctgcgcggcg agcccgacgg cgtccagcag gtccatggcc acaccccgtg
    21121 ccccggccgc ggagcggccg tcgatccggg ccatgacctg aagctgctcg gcggcggtga
    21181 gggcgggcag cagattcggc tgctggaaga cgatcccgat cttgcggcgg cgcagttcgg
    21241 cgagctcccc gcggttcagg ccggtggtcg tggtgccgtc gacggtgacg gtcccccggt
    21301 ccggggtgat gagggtcgcc gcgacggcga gcaggctgga cttgccggag ccggaggggc
    21361 cggcgaccgc ggtgagcgtg cccgccggga cctccaccgt gacgtcgtcg agcgcggtga
    21421 ggcgggtgtc gccgtcggga taggtcaggg tgacgccggt caggttcagg ctcatcgggc
    21481 actccccagt gcggtcagcg ggtcgacgga agtgatgcgg cgcacggaga gtgcggcgcc
    21541 cagcgcgccg agcaggatca tcacggcgga cggcacgagc acggtggccg gagtgagcag
    21601 gaagggcacg gcggagccgg cgaccaccgt gccgagcccg acggccaacc cggttccgat
    21661 ggcggtgccg ccgacgagaa ggacgacggc ctggcctagc gcgtccttca gcaggaaggc
    21721 ggtactcgcc cccaacgcct tgagaacggc gatgtcaccg ctgcgctgga tggtccacac
    21781 ggtgaagaag gcgccgatca caagggcgga gatcgcgaac aggaagccac gcatcagctg
    21841 cagcgaaccg ttttccgagg tgtaggagcc gatcgcggac agcgagtcgc ccttcgacac
    21901 cgtcgtggtg cctgcggtga ggtcggtggc ggcgagatcg gcgccggccg tcgtggtcag
    21961 cgcgagcacc gtcgcgctcg gctcgccgtc ggccggtggc gccgtcttcg cccagacgtc
    22021 gaggcctgcc cagatcacgg gcgtgtggct gaaccaggcg tcccccgcca ccgcggcgac
    22081 cgtcagcgga cgcccggcca cggcgacggt gtccccgctc cgcacgccca gatcctcggc
    22141 ggcggacgtc gacagcacca ccgagtcgcc gctgatcttc tcgctgtccg gggcgagcgc
    22201 cgacccggtc cggacaccga aaacggagat cccggcgctg cggtcgcccg cgacggcctt
    22261 ggtggtggcg atgcccagcg gttcggccgc ggtgacaccc ggggtctcgg cccactggcg
    22321 gcgctgtgtg tcggtgatcg cggaattcgc gtaggagagg ctctgcccgg cagcgggggc
    22381 ggcgaagacg atcttgtccg cgggcaggcc ggtgatcgcg gaggtgttct gctcacccag
    22441 gcccgcggtg agcccggaca acaggcctac caacagggtg atcaggacga cgacggcacc
    22501 catcagagcg aaccgtcctt tggcgaatct cagatctctc caggcgacga acacggttgg
    22561 ggctgtcctc tcggggtggg ctgggtacct ctccacgatc gccgccggtg accgcgacgg
    22621 catccggccg gagatggcac ttcccctgcc ggaagacggc acgccgcctc tacctttgga
    22681 tagaggcgcc cgccgatccc gctccgtaat ctggacgcac tgtgaccgcc gcgtccgctt
    22741 tgaccccgac cagccgggtg ttgacctggt gtctgcacct gctgctcatc gccctgctca
    22801 cgctggcggc cgcccgggcg gtggcggacg gctcaccaga cgcgggaacg atcgtcgcgg
    22861 cggcggtgac gtgcgccgcg gtgtacgcgg ccggcccgct tctgcctcgc gtccggacgt
    22921 cccggcgggc cgccctgtgg tggctgatcg cggtgggcct cgtgtggctg gtcctgctgg
    22981 tgctgaccgc cgacggtgtg tgggtcgcct tcccgctgta cttcctgcag ttgcatctgc
    23041 tgccccgccg tcagggcctg gtcgcggtga tcgcgaccgc gctggcggcg atcaccgcgt
    23101 tcgccgccca ccagggttcg ttcgcccccg cggcggcgat cggcccggca ctcggcgccg
    23161 ccgtcgcggt cgccgtcgtc tggggctatc aggcgctgta ccgcgaaagc gaacgacgcc
    23221 ggaacctgat cgaggagctc accgccactc gcgccgacct cgccgcggcc cagcacgagg
    23281 cgggagtgct cgccgagcgg gaacgcctgg cccacgagat ccacgacacc ctcgcccagg
    23341 gcttgtcgag tattcaactc ctgttgcgtg ccgcggaaag gactctgccc gataccgcgg
    23401 ggaacgccgc ccgctacgtc gaacaggctc gtcaagccgc cgcggacaac ctcgccgaag
    23461 cccgccggtt cgtcgtcgcc ctgtcgcctc ccgcgctcga cgacaccacg ctggccgacg
    23521 cgctggcacg gctgtgcgcc acgaccaccg cccggcaccg gatcaccgcg cgcttccatc
    23581 tcaccggtga ccccgttccg ctgccgaccg cgcacgaggt ggtgttgctg cgcatcggtc
    23641 aagcggccct ggcgaacacc gtccggcatg ccgacgcgtc caccgccgaa gtcacgttga
    23701 gttacgacgg cgaccaggtc accctcgtcg tcgtcgacga cggcgtcggc ttcgacccgg
    23761 accacagcgg cttcgggctc accgcgatgc gcacccgggc cgaagcgctg gacgggatct
    23821 tcaccgtcga gtcctccccc ggccacggca ccaccgtgtc cgcgcgactg cccaaggaat
    23881 gcccgtgacc gaacccccga tccggctcct gctggccgac gaccacccca tcgtccgggc
    23941 gggactgcgt gccgtgctgg aaaccgagcc cggtctcgtc gtctcggccg aagccgcgac
    24001 cgcggaagaa gcggtggccc gggcggccga aggcgacatc gacgtcgtgc tgatggattt
    24061 gcgtttcggc tccggcatga ccggcgccga ggccaccgcg gcgatcacgg cgcggccgga
    24121 cgctccacgc gtactgatcg tcaccaccta cgacaccgac gccgacaccc tgcccgccat
    24181 cgaagcgggc gccaccggct atctcctcaa ggacgcccct cccgaggatc tggccgccgc
    24241 cgtgcgcacc gccgcggccg gacgcaccac gctcgcgccg accgtcgccg accggctgat
    24301 gaaccggatg cggatgcccg ccaccgcact gacgctgcgc gagatcgaag tcctgggcct
    24361 ggtcgccgac ggcctgtcca accgggccat cgccgaccgg ctccacctga ccgagggcac
    24421 ggtgaaatcc catctggccc gcagctacac caaactcggc gtcgattcgc gcaccgccgc
    24481 cgtcgccacc gcgaccgacc tcggcctgat ccggcgctga acgggcgagg tggcaaggac
    24541 ttccgagtgc acttgagtga aaaggccgaa gtccgtgaag gcctccttga gggactctgg
    24601 gtccctcaag gaggccttca cggaccggtc cgtggccaag ctcattcagg agccagtagg
    24661 cgctcctagc cacgtacgag cctcatatgg gtatgaacag gtggctacca cccacaagtg
    24721 aatcagtgcc cgagcacgcc gctgacctcg ttcggcgtgc ccggaatcgt tccggtcgcg
    24781 gtcttcgtac ccgacgcgag gtccaccgag tggatttcct tcttgccggg atcggtgacg
    24841 taggcggttc cgccccgcac gaagatcgcc gggcgcggct gctgccactc gatcggttcc
    24901 tgccaggtgc cgagcacggc gatcttccgc gtcaccgcac cgctcaccgg gtcgatcacg
    24961 tggatctgcc cgtccgtacc caggaccagt gcctcaccct gaggcccccg ggccagcgac
    25021 cggaaggtgt agctggtccc gatgtcgacg tgcttgaggg tggccttctc ggtgtcgatc
    25081 agggagatcc gggtcgggcg ttcgagttcg gccgcttcgt cgaccttgta gtcgcccaag
    25141 gtgatcgggg agacgtccga gcccgcctgg ttgccgatgc gtccgtaggg gtccgggctg
    25201 gtcaccttgg tgatgacgcc gttgcggtag atcagcacgc cggtctggca gccgaccacg
    25261 accgcttcgc cgcgcgcggc ggcttcaccg tgcacgccgg ggcactgctc gttgcgcgcg
    25321 atctccttct tgtccttgtc cagcaccacg atcccggacc gcttgtcctc gttgccgacg
    25381 gtggtgagca gttcgccgtt cgcgagttcg acggccacgc cgtgatgcgc ctcgggcgtc
    25441 ttgtgcttcg gcgcggggaa agccgcggta ccgatcgtct tcgggtcgaa gacggtcact
    25501 tcaccggttc cgtcggcgaa cagcaccgtc ttgccggcgt gccggacgac gtgtcccggc
    25561 ttggccgcct tcacctcgtt gtccgtgagc acggcaccga cggcgtcgag gacccggaag
    25621 ccggtggagg tcgagaccag gaggtgccgg tcgttcccgg cggggttgag ccggttgaag
    25681 ccttccagcg gaaggttctt cgcctccttc aaggtcttgc cgtcgagcag gacgattccg
    25741 ccgtcatagg tgacggcgac cggatcggcg acgaccgatg ccggagccgc gtccttgccg
    25801 ggctccgccg ccggctgttc ggtcccgcag gcggcgagtg cgagcgtgct cgccgtcgtc
    25861 gccatcagcg cgagatatcg ggctttccgt gccattttcc tgtgcctttc gtctgttccg
    25921 gtcaggaacg ggtcaaaccg gtggtgatcg attcggtgtt ggcgcgcatc atttccagat
    25981 aggtggccgc gccctggcct ggttcactga gcgattccga gaacaacggg gccacctgga
    26041 cgtgcagtcc ggcctgctcg gccaagaccc gcgcgagccg gtccggttgc gaggaatccg
    26101 cgaagatcac cggaactccg gccgcgcgaa cggtgtcggc gagtgccttc agatccgagg
    26161 agcttggtga agcgagcgtg gtcccaccgg ggatcaccgc gccgacgacc tggaagccga
    26221 accgctgggc caggtagccg aacacgtggt gattcgtgac cagcttccgg cgctcgggcg
    26281 gaatcccgcc gaacttctcg gtcatcgcct tgtcgagcgc ctcgatctcc ccgcgatagc
    26341 gttcggcgtt ggcgcggatc accgcttcgt cgaccccgtc gacatgggcg acgacctcgt
    26401 cggcgatcgt cttcaccgcg tcgcgcaccc gtgccggatc cgtccagaag tggggatcgg
    26461 gcttgttgtc ggcgtaactg atcgggttca cccgctcccc ggcgggcagt gccggtacgc
    26521 cgctttgctc ggccgtgcgg acggtgcgca ggattccctc ttcgagcccg agtccgttgt
    26581 agacgatcag gccggcccgc tcgacctgag cagcctgctg tgcggagatc ccgaaggagt
    26641 gcgggtcggc gttgggcttc atcaacaccg tcacctcggc ctggtcgccg acgacggcgc
    26701 gggtgatgtc gccgaggatg ttcgtcgtga cgacgaccga cttgccgccg ccaccggtcc
    26761 cggagcagcc ggccgccgcc agcaccgcca ccacgaccag ggcgagtacg cggcgcctca
    26821 tcggccggtc tccacgatgt ggccagcctt gccgccgacc ttcagcgtcc tggcgcggcg
    26881 aaggttgtcg ttgtagtcga tctcgtacac ctcggcggag agcgggttgt tgagataggc
    26941 gcgggtcgaa tcgacctgga tcgacggaac gccggcggcg gtcgcttccg gtgtcagcag
    27001 cgggacggcc gtctgttcct ttccggtgcc atcgaaggag cgcagctttc cgtcccgcgt
    27061 gaggaccaaa agcgggccac cctcgccgac ggcgttcacc gcggcgaccg ggccggtctc
    27121 gacgtgctgc cagctgcgac gcccgacgtc cagcgaccac accgcggact ccccagcccg
    27181 cgccgcgagc gtcgaaccac cgggccggtg cgagaaggcg gtggcgcgtt cctgcgcgct
    27241 gacatcgcgc gggtacggga tcttgacccc ggagaacgcg ccgtcctttt cggtcaccag
    27301 cagggcgccg tccgcgcagc cgaagacggc tccgcgcctg gtgacggcct ggccccgcaa
    27361 gtccgggcac ggctggtcga tctccgcgac gactttgccc tgacggtcgt ggacgcgcac
    27421 gccgcgggcg agcgtctttc cggcgtccgc caccgtggcg atgatgtgct cacggtaagg
    27481 gatcgcgaca ctcgcgtgcg gctcacgggt gatcttcccc agttcggtca cggtgccctt
    27541 gtcgagcgcg gttcgatcca gcaacgtcgt cgtaccgtcc gaataggaca gtgcggtgac
    27601 cgcgggatcg ctgtagaccg ccaagggctg ttttccgggt gccacgccga catcccggac
    27661 cttcgcccgg tagtagtgga cgtggtcacc gtggtcgacc atccacgaac cgctgtcgat
    27721 cacccggatc gtgccgtcgc cggcggtcag gtagccgaag cgaccgtcac ccgtcacggc
    27781 ttgcactccg tcgactcgcc cggcctcgtg cacctcctcg gtgatcaggt cgacgacgcg
    27841 tacggcgccg gtgtccgtgt cggcgacgat cagccgcgac tgggcctcgg ccgcctcctc
    27901 ggcgccttcg acgtagccgt gtgggacttc cgcggtcacc tcccccggct gctccgagcc
    27961 gcacgccgcc agggtcagcg ccgcgacgac cgccgtcact gctttcagtt tcatcgtgag
    28021 ctctcgatct ccggagtcag ggaacggaat cgctgtcgta cgaaggacag gaacgcggaa
    28081 aggaagaaca ggaggaccgc gccggcggcg atggtcgcgc ccgccgcggt gccccaatgc
    28141 caggacacga gcaggccgcc gagcgtggcg gcgacgccga gcaacgccgc gatgagcatg
    28201 atcgtggtga tccgcctcga ccagaagagc gccgccgcgg cgggggcgat gagcaggccg
    28261 aacaccagca acgtccccac gacgcggaac gacgcgacga tcgtcagcgt gaccagcccg
    28321 agcagcaccg cattcgccag gcgtggacga agccccagcg tgtgcgcttt gcggacgtcg
    28381 aaggtgagcg cggtgaacga acgatgtccc gccagtgcca ccgcccccac gacgagcagg
    28441 gtgaccgcga ggcccaccag gtcacccgat ccgacggcga gcacgtcgcc gaacaggaac
    28501 ccggtgagat cgaccgcgaa cgaccgcgaa tgggacacga tgatcacgcc gctcgcgagc
    28561 atgccgacga agagcagccc gatcgtggtg tcctcggaca gccgccgcga acggccgagc
    28621 gccgtcacgc cgagcgccat caccccggca ctgatcgccg cgccgatcag caggttcacg
    28681 ccggtcagcg aggcgatcgc cacgccgggc aacatgccgt gcgacatcgc gtcgccgatg
    28741 aaggccatgc cgcgcaatac cacccaggtg cccacgaccg cgcacaccgc cgagacgagc
    28801 acccccgcca ccagcgcacg ctgcacgaac gacacctcga aggggatcag caaccagtcc
    28861 acgcgtcaca ctatagtggt aatgattgtc attatctgaa agaggtgtga tgaccccgga
    28921 cacagcggcg ctcacgatcg accgcgcgca cgcccactac ggctcccgcg aggtgctgcg
    28981 cgggatcacc gcccaggtac cgtccgcacg gctcaccgcg atcgccggcg cgaacggcgc
    29041 ggggaagtcg tcattgctga acctcgtcgc gggcgtgctc ccgccgacca ccggttcggt
    29101 gacccgggga gaccaggggc gtgtcgccta cgtgacccag cagagcgagg tgtcgcggtc
    29161 gctgccgatc accgtccggg ccaccgtcac gatgggacgc tgggcacacc gcggacactg
    29221 gcgccgactg tccaagatgg accggaagat cgtcgaagaa tgcctggaac tactggagat
    29281 cacgtcgatc gcggaccggt tgatcggcac gctgtccggc gggcaacgcc agcgggcact
    29341 ggtggcgcag gggttggctc aacgagccgg gctactactg ctcgacgagc cgtcggccgg
    29401 cctcgatcta cacgcccgtg gactgatcga gaaagccctg cgggcaacac tcgcggaagg
    29461 cacgacggtc ttgcgcgtca cacacgacct cgaggtggca ggccgggccg atcactgcct
    29521 gctgctccag gacggccgac tggtcggcga aggcgtgccg gcgtcggtgc tgaccccggc
    29581 gcgcgtggcg gaggcctggg gcttgccggt gatcggcgac gccgcccttg acgtgcacgg
    29641 cacgcccggc gcccacccga tccggccggt tcagtaacat cgccggtatg ccatcaccat
    29701 tcgagggagc agcctcatgc cttccgcgat aagcaagcgc ttagtcaccc ttggcgattc
    29761 cttcaccgag ggtgtcggcg acgacgaccc ttcgtcgccc aacggcgtcc gcggctgggc
    29821 cgaccgcgtc gcggccacac tcgcggccaa ccaccaggac ttccgctacg ccaatctcgc
    29881 gatccgcggc aaactcctgg ggcaggtcct cgccgagcag ctcgacccgg cgctcgccct
    29941 gaatccggac gtcgtgacgc tgtacgccgg cggcaacgat ctgatgcggc cgaaggtcga
    30001 tatcgacgct ctcctcgacg actacgacgc cgctgtcggg aaggtcgtgg ccacgggcgc
    30061 ccgggtcgtc ctcttcaccg gtgtcgacgg ggtcgaagac gcgctgttcc gcaggatccg
    30121 cggccgcgtg gcgatctaca acgagcatgt ccgcggtatc gccgcgcggc acgagacgct
    30181 gctggtggac atgtgggcga tgcggcaact gcgggacagg cggctgtggg cgccggaccg
    30241 gctgcacctg aactcgttgg gacacaatga gatcgccatt gccgtgctcg acgcgctcgg
    30301 cgaaccgcac aagctgacgc ccgccgaact cggaccgcga ccgctgctga gcccgcgggc
    30361 gcggcgcacc gagaacctcc agtggggcaa ggagcacgcc gtgccgtgga tcaagcgcag
    30421 gttgcgtggt gaatcgtcgg gcgacgagct cgcgccgaag cggccgacga tggatcctta
    30481 cgcctgacgc ggacgaagcc cgtcgaagag gatgcagatc gtccgggccc ggaattcggg
    30541 tccggcatgc tccgccgcct tcgccgttcc gatgatcacc gggatcagtt cgtcgacgcc
    30601 gagatccttg cggacgtcgc cggtgtcctg cgcccggctg agcagaacgc cgagcgcgtc
    30661 cttcaggcgg acaccgatga ccgacccggc cgagggaacg ctgacgccgg ccgccgacag
    30721 ggcttcgaag taggcgttct tggcgcccga catctcgatc cagccggtga ggaacccgaa
    30781 gaacgcggcg cccgggtcgg gtgaatcggc ggccaccgtg gcctctgctt cgtcgacgaa
    30841 gcggtgaagg cgcgcgaaga gcacggcctc cagaagcgcc tctttcgtgg gaaagtgccg
    30901 gaacacggtg ccgactccga cgcctgcttc gcgggcgact tcttcggtcg gcgcgctggt
    30961 gcctttggcc gtgaagacgc gctccgcggc ctccaacacc cgtgtgcgat tacggcgggc
    31021 atcggctcgg agcggtttct cgtccgtcac agcggggatc ctagacccgc tgtcgagagc
    31081 ttgtcccgcg gctcacctat gttttccggt ccggcatctc gtccagcacg cgcgccagtg
    31141 ccttcgggac cccggtgcgc cagccgccgc ccatgatccg ccgcgacatc cgctggaact
    31201 cgtcgtcggg atcgaagccc tcgtggctga ggaacagcct ggtcccccgg ccctccggca
    31261 cgagccgcca ggtgactgtc cattccggac cccagctgat gctcagcaac cgttccggct
    31321 cgacggccag cacctcgcag gcgaccggcc cgccctcgaa cccggcggcg ggaacggggt
    31381 ccgcgagcag ctcgaaccgg tgtcccacaa cgggtttgat gtcgttcgac atccggagcc
    31441 agcgttccag cagctgtggt tcggtcagcg cgcgccacac cttgcgcggc ggatgcgcca
    31501 ggaactggtc gacgtgaatg gccgtcgggt cctcgtcgtt cagaactcct cctcgtccag
    31561 caggtcacgc aggttgccca gcttgccgcg ccagtagcgc tcgtagggcg aaagccagtc
    31621 cgagacctcc tgcagcggcg cggcctcaag aaagtagacg cgattccggc cctgccgctc
    31681 ctcccggacg agtccggcct cgcgcagcac ccgaaggtgt tccgacaggc tgggccgccg
    31741 catgtcgaag cgttcggcga tctcccccgc cgcccggggg ccgtcgagaa ggatgcccag
    31801 cacctcgcgg cgggccgggt tggcgagcgc ggcgaagacg tcgtcgttga ccggcactag
    31861 cgcggccagt cgccgtaacc ggacggttcg agcaatccca tcgcgttgcc gtcgggatcc
    31921 ttcaacgagg tcacgcggcc ccacggcatt tcctccgcgt cgtcgacctc gatgccctgt
    31981 gcgcgaagct ccgcgatgtc ggcatcgacg tcggcggtgc tcagctggaa atgcacacgc
    32041 gtctcgaggt cgagcccgcc gacggcgcgg tcgaccagga cgatgccggt ctccgccccc
    32101 ttggggccga ccatgacgaa cgggccgtgc gggccgctga cgtcgacgag caggtcgaag
    32161 ccgagcttgc cgacgtagaa gtcccgcgcc ttcgcctgat cggcgaccgg cacggtgagg
    32221 aactggatgc ggtcgatgtt catgccgcca ccatacgtag gatttttcct acatgtcaac
    32281 tccgacgaag aggaacatcc gcgctccgga ggccgctgga cagaagtcct gcgtccgaag
    32341 gctcgcaacg acaaccaccc ttacaacatc tacttaaata gaggtccagg tttcgtgacc
    32401 agggccgcaa gagcttgagt tcacctatgg acgagctttt agcgtcttcc ccatgaccgc
    32461 agagaacacc acccagtccc ccgttcgcct cgccgtgatc atcggcagtg tccggcacga
    32521 acgcttcgcc gacgccatca cgggctggct gctgaccgaa ctcgccgcgc tcgacgggct
    32581 ggaggtggat cccatcgacc tcgccgacat cgatctgccc ttgcagggaa cacagcccgg
    32641 cggcaccgag acggtgatca gcgacaggct gcgcgcggcc gacgcctacc tcgtcgtcac
    32701 cccggagtac aaccacagct tcccggcggc actgaagaac gccatcgact ggcacttcac
    32761 cgagtgggcg tacaagcctg tcgcgttcgt cggctacggc gccggttcgg gcggtatccg
    32821 cgcgatcgag cagttacggc tgatcttccc cgagctgcgg gccaccacga cccgcgacgc
    32881 ggtgctcctg aacgctccgt ggacccgtct cggcccgaac gggtacgagg gcaccgacgc
    32941 cgagcgcggt gcgctggccg cgacgatgac cgaactgggc tggtgggccc gcaccctgcg
    33001 tgccggccgc gtcgcgactc aggcgagtgc ggcatgaacc gcctgaccgg acaagaactg
    33061 cgcatcgcct cggtgatcgc gctcggcggg ttgatggccg ttctcgacac cacgatcgtc
    33121 gccgtcgcgc tgccgcggtt catgacgacg ttctccgcgt cgctcaccac gatccagtgg
    33181 atcgcgaccg cctacgcgct cggcatggtc gcggcgatgc ccctcgcggc gactttcgcg
    33241 caacgctggg gagcgcgccg ggtgtacctg gccgcgctgc tcgtgttcgc ggtgacgtcc
    33301 gcggccgccg gtgctgccgt cgatctgggc tggctgatcg ccgcacgagc ggtgcagggc
    33361 ctcgccggcg gcctcatcaa cccactgggg atgaccatcg gtttcggcgc ggtggcgccg
    33421 gaacgccgga gccggatgac cacgatcacc ggtctgccct tgctgatcgg gccgatcctc
    33481 ggcccgatgc tcggcgggct cctgctggag aacctctcat ggcgggcact gttcttcatc
    33541 accgttccgc ctgccttgct cggtgtcgcc ggtgtgctgc gctgggtgcc cgccgacatc
    33601 ccgtcggcgg aacgcgcccc gatcgatttc gccggtggac tgctgctcgt ccccggtgtg
    33661 gtcgcggtgg cgtacggatt cagcgaagag accctcggca tggacgtccg ggcgatcatc
    33721 gtcgccgccg gactggcact catggccgtg ttcctccgaa ggtcgtggca ccatcacgcg
    33781 ccgctgctga acgtccggct cctgcgcgat cgcacgttcg ggcgcaacgc cgcgatcctc
    33841 gtcctgtacg ccgggccgta cttcggctcg atgctgctga tgcccgccta catccaggtg
    33901 atgcgcggcg attcggccat gatcagcgcg ctgatgatgg tgccgagcac gatcgggatg
    33961 ggcctcacca tccagttcgc cgcccgcgta ctggaacgct tcggcccgcg gatcgtcgtc
    34021 gggaccgggt tgagcttcgc gatcatctcg accgcactga ccatc
//
