LOCUS       NZ_JAEVFI010000043     14775 bp    DNA     linear   CON 14-SEP-2024
DEFINITION  Streptomyces sp. JJ66 scaffold43_size17030, whole genome shotgun
            sequence.
ACCESSION   NZ_JAEVFI010000043
VERSION     NZ_JAEVFI010000043.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces sp. JJ66
  ORGANISM  Streptomyces sp. JJ66
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 17030)
  AUTHORS   Jose,P.A. and Jha,B.
  TITLE     Draft genome of Streptomyces sp. JJ66
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 17030)
  AUTHORS   Jose,P.A. and Jha,B.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-JAN-2021) Marine Biotechnology and Ecology Division,
            CSIR - Central Salt and Marine Chemicals Research Institute, G.B.
            Marg, Bhavnagar, Gujarat 364002, India
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 25-MAY-2017
            Assembly Method                   :: Velvet v. V 1.2.10
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 320.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_019303495.1-RS_2024_09_14
            Annotation Date                   :: 09/14/2024 03:51:48
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,515
            CDSs (total)                      :: 4,446
            Genes (coding)                    :: 4,340
            CDSs (with protein)               :: 4,340
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 61
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 31 of 106
            Pseudo Genes (incomplete)         :: 82 of 106
            Pseudo Genes (internal stop)      :: 3 of 106
            Pseudo Genes (multiple problems)  :: 9 of 106
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 09:22:12
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2255
            Orig. end                         :: 17030
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JAEVFI010000043.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..14775
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="lanthipeptide-class-i"
                     /region_number="1"
                     /rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..14775
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="lanthipeptide-class-i"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..14775
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[10000:14714](+)"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..14714
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
     gene            complement(363..2480)
                     /locus_tag="JJV70_RS21445"
                     /old_locus_tag="JJV70_21430"
     CDS             complement(363..2480)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1090: acetyl-CoA carboxylase biotin carboxylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014154746.1"
                     /locus_tag="JJV70_RS21445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJV70_21430"
                     /product="biotin carboxylase N-terminal domain-containing
                     protein"
                     /protein_id="WP_219049688.1"
                     /sec_met_domain="ATP-grasp (E-value: 3.2e-09, bitscore:
                     26.6, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MISTLLVANRGEIARRVFRSCRDAGIATVAVYSDADATAPHVTEA
                     DAAVPLPGTAPADTYLRGDLVVGAALAAGADAVHPGYGFLSENAGFARAVTDAGLTWVG
                     PPPEAIAAMASKTRAKELMRAAGVPLLAPLDPDAVTEADLPVLVKAAAGGGGRGMRVVR
                     ERGALATQLAGARAEAASAFGDGEVFIEPYLEHARHVEVQVLADAHGTVWALGTRDCSL
                     QRRHQKVIEEAPAPALPDALRATLHTAATEAARAVGYVGAGTVEFLVTGVRGDPGVGSA
                     PGAGRAYFLEMNTRLQVEHPVTEEIYGVDLVALQLRVAEGERLDDQPPTPRGHAVEARL
                     YAEDPARDWQPQTGTLHRLTLPPGVRLDSGVADGDVITPHYDPMLAKVVAWAPTRAAAI
                     RKLAHALAAARVHGPVTNRALLVRSLRHPQFVAARLDTGFYDRHLDALTAPDDTLTAPD
                     ADEDPGAVSAPGAATAAPTAASLHALAAALADSARAHGGPGARLGGWRNLPSQHHTKTY
                     RAEPGGTEHTVRYRRTRAGLDAPGHPGVRLLHAAPDRVLLEVAGVRRVFHVAAYGDRVH
                     VDSPLGAHAFTALPRFPEPGVRAEPGSLLAPMPGTVVRVAAGLTTGQRVEAGQPLLWLE
                     AMKMEHRVTAPAAGTLTALPVEPGRQVEVGTLLAVVTDDTASTVGTASTPSTADATGTA
                     HTAHADEGTRS"
     gene            complement(2492..4090)
                     /locus_tag="JJV70_RS21450"
                     /old_locus_tag="JJV70_21435"
     CDS             complement(2492..4090)
                     /EC_number="6.-.-.-"
                     /GO_function="GO:0016874 - ligase activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1059: acetyl-CoA carboxylase, carboxyl transferase,"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018567104.1"
                     /locus_tag="JJV70_RS21450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJV70_21435"
                     /product="acyl-CoA carboxylase subunit beta"
                     /protein_id="WP_219049689.1"
                     /transl_table=11
                     /translation="MTVLPTRLDPAAPEYAAHREAMLGKLAELDAEHAKALAGGGEKYV
                     RRHRERGKLTARERVELLLDPDTPFLELSPLAAWGSDYTVGASLVTGIGVIEGVECLIT
                     ANDPTVRGGASNPWTLKKALRANEIASANRLPCVALVESGGADLPSQKEIFIPGGALFK
                     DLTRLSAAGIPTIAVVFGNSTAGGAYVPGMSDHVIMVKERAKVFLGGPPLVTMATGEVA
                     DEEELGGADMHARVSGLADHFAEDEPDALRQARRVVARLNWRKAHADPPPAPPPEYPEE
                     ELLGLVPADLKAPFDPREVIARVVDASDFDAFKPRYGTSLVTGWARLHGYPVGILANAR
                     GVLFSAESQKAAQFIQLANQRDIPLIFLHHTTGYMVGTEYEQGGIIKHGAQMLNAVSNS
                     RVPHLSVLLGASYGAGHYGMCGRAFDPRFLFAWPSAKSAVMGPRQLAGVLSIVMRESAA
                     AKGQPYEEEADAGLRALVEEQVEAESLPLFLSGRLYDDGVIDPRDTRTVLGLCLSALHS
                     APVRGARGGFGVFRM"
     gene            complement(4087..5772)
                     /locus_tag="JJV70_RS21455"
                     /old_locus_tag="JJV70_21440"
     CDS             complement(4087..5772)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018854188.1"
                     /locus_tag="JJV70_RS21455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJV70_21440"
                     /product="acyclic terpene utilization AtuA family protein"
                     /protein_id="WP_219049699.1"
                     /transl_table=11
                     /translation="MVVRVGNASGFYGDRASALREMLTGGPLEAVTGDYLAELTMLILG
                     RDRLKDPARGYARTYLRQLEDALGLAHERGVKLVSNAGGLNPGGLADAVRELAGRLGVP
                     VRVAHVEGDDLTARGGWGEGVLTANAYLGGAGITACLQAGADVVITGRVSDAALVSGVA
                     AWHHGWGAHDWDALAGAVVAGHVLECGTQATGGNYAFWRELPGPPYGFPLAEIDADGGC
                     VITKHPGTGGAVTVGTVTAQLLYETAGPRYPGPDVTARLDTVRLAEVGPDRVRVSGVRG
                     EPPPATLKVGLTRLGGYRNEVTFVLTGLEIEAKADAVREQLREALDAAAPAHVSWTLAR
                     TDHPDAQVQEEASALLRLVVKDADEAAVGRAVSGAAIELALASYPGFHVTAPPGRGQPY
                     GVFTAASVPQGEAAHTAVLPGGTRHRVAPPPVQAGPQHALPVPELPEPLARGASRRAPL
                     GLVAGARSGDKGGSANVGVWVRAEAAWRWLAHELTVERFRQLLPETAGLDVTRHVLPNL
                     RALNFTVDGLLGEGVAAQARFDPQAKAVGEWLRSRHLDLPEALL"
     gene            5908..6354
                     /locus_tag="JJV70_RS21460"
                     /old_locus_tag="JJV70_21445"
     CDS             5908..6354
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020554872.1"
                     /locus_tag="JJV70_RS21460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJV70_21445"
                     /product="prevent-host-death family protein"
                     /protein_id="WP_308294948.1"
                     /transl_table=11
                     /translation="MSFSDLSKNAKRVAEAVEHAQRVHITRRDGEGLFLTTEHHDRQRE
                     ETADVTARLLSALLSSDEGARAVLIALPQVFPWTRHLSPEEMREFVIDLVDAARDATDL
                     DVHANLHRVIVEWRATARLLADPDLAAQLTKPLTSSRHPKDTDT"
     gene            complement(6479..7267)
                     /locus_tag="JJV70_RS21465"
                     /old_locus_tag="JJV70_21450"
     CDS             complement(6479..7267)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="JJV70_RS21465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="JJV70_21450"
                     /product="hypothetical protein"
                     /protein_id="WP_219049691.1"
                     /transl_table=11
                     /translation="MATEGARAAERPFLQRPQGILAVAGGAVALVASVLGLVFLLLPGL
                     QPEPPAPELEIVDFDLDREENVRADWITPDGVEEREDYPASQVTLVLRNPSDNPILITR
                     ADFRFDHVREAGCAYGAGPTEVQARYDIKVPDGKDVPFTLERKMKYTVPPHAQERIAFT
                     LGPERDYAGSLPKIYAFTVTLHADDGTERDIPLMHHIAPVSRMETALSAAQQAMAGQYS
                     LTSPECVREQAREVSEIVDSATYASSELKRFRDELAAVTQ"
     gene            complement(7596..7793)
                     /locus_tag="JJV70_RS21470"
                     /old_locus_tag="JJV70_21455"
     CDS             complement(7596..7793)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF016070.5"
                     /locus_tag="JJV70_RS21470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJV70_21455"
                     /product="DUF397 domain-containing protein"
                     /protein_id="WP_219049692.1"
                     /transl_table=11
                     /translation="MNDCGWQKSSYCAEGNNCVEMRAGDGEVVALRESTEADRVLRLSR
                     PMLHTLLTSVREGRLAELSG"
     gene            complement(7805..8656)
                     /locus_tag="JJV70_RS21475"
                     /old_locus_tag="JJV70_21460"
     CDS             complement(7805..8656)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015037580.1"
                     /locus_tag="JJV70_RS21475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJV70_21460"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_219049693.1"
                     /transl_table=11
                     /translation="MPPRSAPTAREQRLGAELRKLRERAGLTATQAGALLGIDQARMSN
                     IETGRVGLSAPRLRTLACNYDCADEALIDALASMTGRRPRQWWEEYRGLLPQGLLDLAE
                     LEHHAAAMRTAQTATLPGLLQTLDHARAVFAHSIPQLPAHEMEHRTSWRIKRQAVLYAD
                     KAVPYTAVIHEAALRMQFGGRVVARAQLRHILQVSERENLSVLVLPFTAGGFPGAGQTI
                     FYAHGAVPQLDTVQLDQSHGPVLLDAEAQLQKYRQLLDRLEALALTAEESRDFILGIVK
                     VL"
     gene            8825..9274
                     /locus_tag="JJV70_RS21480"
                     /old_locus_tag="JJV70_21465"
     CDS             8825..9274
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004943582.1"
                     /locus_tag="JJV70_RS21480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJV70_21465"
                     /product="ATP-binding protein"
                     /protein_id="WP_219049694.1"
                     /transl_table=11
                     /translation="MNPPAFTALAAPPPLDSADWWFSLRLSNDPQAPGIARTHLRTTLD
                     AYGLDTIVDTAELLTSEVVTNAHRYTDGPVTVRAQYVGTRRRLRVSTGDVSAVAPRLAC
                     ALPADEGGRGLRILDLCALSWGWFPLSDSRDGLAGKVVWYELAAP"
     gene            9789..9920
                     /locus_tag="JJV70_RS21485"
                     /old_locus_tag="JJV70_21470"
     CDS             9789..9920
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LD_lanti_pre"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007491158.1"
                     /locus_tag="JJV70_RS21485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJV70_21470"
                     /product="FxLD family lanthipeptide"
                     /protein_id="WP_219049695.1"
                     /sec_met_domain="LD_lanti_pre (E-value: 5.3e-16, bitscore:
                     48.4, seeds: 21, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQEDEFDLDISILESGDGSAVLVNLTDDGCSPTCEGSCATNVA"
     gene            10001..13099
                     /locus_tag="JJV70_RS21490"
                     /old_locus_tag="JJV70_21475"
     CDS             10001..13099
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lanthipeptide_LanB_RRE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1155: Lantibiotic dehydratase domain protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016325333.1"
                     /locus_tag="JJV70_RS21490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJV70_21475"
                     /product="lantibiotic dehydratase"
                     /protein_id="WP_219049696.1"
                     /sec_met_domain="Lant_dehydr_N (E-value: 1.3e-197,
                     bitscore: 647.7, seeds: 73, tool: rule-based-clusters)"
                     /sec_met_domain="Lanthipeptide_LanB_RRE (E-value: 1.7e-16,
                     bitscore: 50.8, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Lant_dehydr_C (E-value: 6.8e-25, bitscore:
                     78.1, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNHRQDTLYECADTALVRAARYTRLSLPPWPNVTSDAPVQVHQWH
                     AWLKAAWALDEVSDSVEQASPSLARHMDTQCAMVGLPEARQVRRTLISVIRYIQRMTGR
                     ATPNGLFAGVAPAGFGERSEYKWGPWHKAVARVDAAWMSDVITELEACPDLLRRLPVVA
                     ANTAFVRGDRLIVPYPARLATAKPTAEVSLRFTSAVQTALGAARAPIACGLLANKVSSN
                     FPDVPAARVMNLLTDLMRNGALVSSLHAPSSTLDALDHVVGELDAIHAHEVPSIAILLD
                     DLRTVRDNMAQHNRALTPEEGRPLRRELRRKMTEVADTEHPLAVDLKVDCSLTLPHAVA
                     REAEQAATVLARLTPAPFGTPGWKEYHTRFFEKYGIGSLVPLRDVVDPDVGLGFPAGFL
                     DSEPEAREALTQRDQRLLALAQTAVLDGRSEVQLDEELITELESSEHNRAQLPPHLELT
                     FQIHATSTKSLDHGDFTLSAIRPSRGIGTVGGRFLPLLEPEDHARALTVLKRLPSNTPG
                     ALPVQVSLPSLNRAHAQVTRVPELLPAVISLAEHRAADERTVGLDDLAVGCDRRRLYLA
                     SLSRRCLVEPHTVHALDLRVHTPPMARFLVEISRAQSAIITAFPWGAASVLPYLPRVRR
                     GRTILAPARWLLRAADVPARSAAWGEWHEGLNEWCVRRRMPKRVALTEGDQLLPLDLSE
                     SAHRAVLRAHLAQAGTVVLTETSAPGDWFDGRAHEVVVPVTARQPTQWPTVAPVAVNRL
                     LTRDHGHLPGTGPWLLAKLYGHPERQAEILSRHLPYLFAEWETPPLWWFMRHGDPQSHL
                     RLRVAVPEAVDVGQLVSRIGGWGARLRRSGLLNDIQFATTYPETGRWGAGPLMNLAENI
                     FAADSRAVAVQLSQPDRPTPYALTAANFVSLVTAFTGSVTESMEWLVTYGKITDPRRLA
                     RHVLAEAVRLADPTDGWAALRSHAGGPAITAAWAERDQAVARYRARLHESDLDPHLVLE
                     SLLHAHHIRAVGLDKDNERMCVRLARAAALAWTARKGSPRGTA"
     aSDomain        10481..10753
                     /aSDomain="Lanthipeptide_LanB_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing LanB protein in a class I
                     lanthipeptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_JJV70_RS21490_Lanthipeptide_LanB_RRE.
                     1"
                     /evalue="3.20E-16"
                     /identifier="RREFam001.1"
                     /label="JJV70_RS21490"
                     /locus_tag="JJV70_RS21490"
                     /protein_end="251"
                     /protein_start="160"
                     /score="50.8"
                     /tool="antismash"
                     /translation="VVAANTAFVRGDRLIVPYPARLATAKPTAEVSLRFTSAVQTALGA
                     ARAPIACGLLANKVSSNFPDVPAARVMNLLTDLMRNGALVSSLHAP"
     misc_feature    10847..10849
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            13086..14348
                     /locus_tag="JJV70_RS21495"
                     /old_locus_tag="JJV70_21480"
     CDS             13086..14348
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1140: Lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007491155.1"
                     /locus_tag="JJV70_RS21495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJV70_21480"
                     /product="lanthionine synthetase C family protein"
                     /protein_id="WP_219049697.1"
                     /sec_met_domain="LANC_like (E-value: 8.8e-57, bitscore:
                     182.3, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEQRETARLAAAAIADRLASPEDMPGIDLKQGWWPQSLAHGAVGV
                     ALLHIERARAGEGPWQRVHDWLTCAAAGGAIGGPDAHLYYGAPALAFALHSAADRPGRY
                     ARALATLDTHVATLIRQRLQVAHTRMDRGREFPALAEFDTIRGLSGLGALLLHRDTDPA
                     LVESVLAYLVRLTEPVKHDGELLPGWWSHLGPSGTRSPHFPEGHSNNGAAHGITGPLAL
                     LALAARRGISVDGHRTAIKRILSWLDRWQQKGEGGPWWPYWITRDQLRTGRTSPGPFRP
                     SWCYGTAGYARAQQLTALATGDHDRQRAAEIALLGAMTDPSQRAATVDLSLCHGFAGLA
                     HITQLAAADAITPGLGRCLPDLLAPMTNTTPDLLVRPLYRPADGRDIGLLEGAAGTALA
                     LHSFSVGSPAPSGWDACFLIA"
     gene            14364..14714
                     /locus_tag="JJV70_RS21500"
                     /old_locus_tag="JJV70_21485"
     CDS             14364..14714
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR03891.1"
                     /locus_tag="JJV70_RS21500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJV70_21485"
                     /product="thiopeptide-type bacteriocin biosynthesis
                     protein"
                     /protein_id="WP_219049698.1"
                     /sec_met_domain="Lant_dehydr_C (E-value: 5.7e-13, bitscore:
                     39.0, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPQAAWPQRLLKFPAWGEAEATFIEHLLPVLTANDTELTYWSFLR
                     KAPVWRLRYRPTGPAAAKRLDLVLDQLVAAHTLSSWTPGIYEPEETAFGGPSAMDTAHI
                     HFHEDSRHVLEH"
ORIGIN
        1 catcttggtg ctgccgtcgg ccaggccggg cagccagcgg cacctttgcg cctcggtgcc
       61 gaaccgggcg atgacggtgc cgcagatcgc gggcgagacg accatcatca tcagtgggct
      121 cccggccgct cccagctcct ccagcacggc gtacagctcg gtgatgccgc cgcccccgcc
      181 gccgtactcc tccggcaggt tgacgcccag atagccgagc gcgcccgcct cggcccacag
      241 ttcgtcggtg tgctggccct cggaggtgac cttctggacg taggcgcggc cgtagcgcgc
      301 gccgagtgcg gcgacggaag cgcgcaggtc gcgcacctcc tgcgattcca gcagggcgtg
      361 gctcatgagc gggtcccttc gtcagcgtgc gcggtgtgag cggtgccggt ggcgtcggcg
      421 gtgctggggg tgctggcggt gccgacggtg ctggcggtgt cgtcggtgac gacggcgagc
      481 agggtgccga cttcgacctg gcgccccggt tcgacgggca gcgcggtgag cgtcccggcg
      541 gcgggcgcgg tgacccggtg ctccatcttc atcgcctcca gccacagcag cggctgcccc
      601 gcctccaccc gctgaccggt agtcagcccc gccgcgacgc gcacgacggt gcccggcatc
      661 ggcgcgagca gcgagccggg ttcggcgcgg acgccgggtt cggggaagcg gggcagcgcc
      721 gtgaacgcgt gggcgccgag cggcgaatcg acgtgaaccc ggtcgccgta ggcggcgacg
      781 tggaagacgc ggcgcacccc ggccacctcc agcagcaccc ggtcgggcgc ggcgtgcagc
      841 aggcggacgc cggggtggcc gggggcgtcg agcccggcgc gggtacggcg gtagcggacg
      901 gtgtgttcgg tgccaccggg ttcggcgcgg taggtcttgg tgtggtgctg cgagggcagg
      961 ttgcgccagc cgccgaggcg ggcgccgggg ccaccgtgcg cgcgggcact gtcggcgagc
     1021 gcggcggcca gcgcgtgcag cgaggcggcg gtgggagcgg cggtggcggc accgggggcg
     1081 gacacggcgc cggggtcctc gtcggcgtcc ggggccgtca gcgtgtcgtc cggggccgtc
     1141 aacgcatcca ggtgccggtc gtagaacccg gtgtccaggc gggcggccac gaactgcggg
     1201 tgccgcagcg agcgcaccag cagggcgcgg ttggtgacgg ggccgtggac gcgggcggcg
     1261 gccagcgcgt gcgccagctt gcggatcgcc gccgcgcggg tgggcgccca ggcgacgacc
     1321 ttggccagca tcgggtcgta gtgcggcgtg atgacgtcgc cgtcggccac cccggagtcc
     1381 agccgcacgc cgggcggcag ggtcaggcgg tgcagggtgc cggtctgcgg ctgccagtcg
     1441 cgggccgggt cctcggcgta caggcgggcc tcgacggcgt gcccgcgcgg cgtcggcggc
     1501 tggtcgtcca gccgttcgcc ctccgcgacg cgcagttgca gcgcgacgag atcgacgccg
     1561 tagatctcct cggtcaccgg gtgttcgacc tggagccggg tgttcatctc caggaagtac
     1621 gcccgcccgg cgccgggggc gctgccgacc ccggggtcac cgcggacgcc ggtgaccagg
     1681 aattccaccg tgcccgcgcc gacgtagccc accgcgcggg cggcctcggt ggcggcggtg
     1741 tgcagcgtgg cgcgcagcgc gtcgggcagt gcgggcgccg gggcctcctc gatcaccttc
     1801 tggtggcggc gttgcagcga gcagtcgcgg gtgcccagcg cccacacggt gccgtgcgcg
     1861 tcggcgagta cctgcacttc gacgtgccgg gcgtgttcga ggtacggctc gatgaacacc
     1921 tcgccgtcgc cgaacgcgga cgccgcctcc gcgcgggcgc ccgcgagctg agtggccagc
     1981 gcgccccgtt cgcgtacgac gcgcatgccg cgcccgccgc cgcccgcggc ggccttgacc
     2041 agcaccggca ggtcggcctc ggtgaccgcg tccgggtcca gcggggccag cagcggcacc
     2101 ccggcggcgc gcatcagctc cttggcgcgg gtcttggacg ccatggccgc gatcgcctcc
     2161 ggcggcgggc cgacccacgt cagcccggcg tcggtcaccg cgcgggcgaa accggcgttc
     2221 tcggagagga agccgtagcc ggggtgcacg gcgtcggctc cggcggcgag cgcggcccct
     2281 accaccaggt cgccgcgcag ataggtgtcg gcgggcgcgg taccgggaag cggcacggcg
     2341 gcgtccgctt cggtgacgtg tggtgcggtg gcgtcggcgt cggagtacac ggccacggtg
     2401 gcgatcccgg cgtcccggca gctgcggaac acgcggcgcg cgatctcacc ccggttggcg
     2461 acgagcagtg tgctgatcac aggtcactcc ctcacatccg gaagacgccg aagccgccgc
     2521 gcgcgccccg caccggcgcg ctgtggaggg ccgacaggca caggccgagc acggtgcggg
     2581 tgtcgcgcgg gtcgatcacg ccgtcgtcgt acagccgccc ggacaaaaac agcggcagcg
     2641 actcggcctc gacctgctcc tcgaccaggg cgcgcaggcc cgcgtcggcc tcctcctcgt
     2701 acggctggcc cttggccgcc gccgactcgc gcatgacgat cgacagcacc ccggccagct
     2761 gccgcggccc catgacggcc gacttggcgc tcggccaggc gaacaggaag cgcgggtcga
     2821 aggcgcgtcc gcacatgccg tagtgcccgg cgccgtagct cgcgccgagc agcaccgaca
     2881 ggtgcggcac ccgcgagttg gacaccgcgt tgagcatctg cgcgccgtgc ttgatgatgc
     2941 cgccctgctc gtactccgtg ccgaccatgt agccggtggt gtggtgcagg aagatcaggg
     3001 gtatgtcgcg ctggttggcg agctggatga actgggcggc cttctgcgac tcggcgctga
     3061 acagcacccc gcgcgcgttg gcgaggatgc cgacggggta gccgtgcagg cgcgcccatc
     3121 cggtgaccag gctggtgccg tagcggggtt tgaacgcgtc gaagtcggag gcgtccacga
     3181 cgcgggcgat gacctcgcgc gggtcgaacg gcgccttcag gtcggccggg acgaggccga
     3241 gcagttcctc ctcggggtat tccggcggcg gggcgggcgg cggatcggcg tgcgccttgc
     3301 gccagttcag gcgggcgacg acgcggcggg cctggcgcag cgcgtccggc tcgtcctcgg
     3361 cgaagtggtc ggcgagcccg gagacgcggg cgtgcatgtc ggcgccgccc agctcctcct
     3421 cgtccgcgac ctcgccggtg gccatcgtga ccagcggcgg gccgcccagg aagaccttcg
     3481 cccgctcctt caccatgatc acgtggtccg acatgccggg cacatacgcg ccgcccgccg
     3541 tggagttgcc gaacacgacg gcgatcgtgg ggataccggc ggcggacagc cgggtgaggt
     3601 ccttgaacag ggcgccgccc gggatgaaga tctccttctg gctcggcagg tccgcgccgc
     3661 cggactccac cagcgccacg cacggcagcc ggttcgcgga agcgatctcg ttcgcgcgca
     3721 gcgccttctt cagcgtccac gggttgctcg cgccgccgcg cacggtcggg tcgttggcgg
     3781 tgatcaggca ctcgacgccc tcgatgacgc cgatgccggt gacgagggag gcgcccacgg
     3841 tgtagtcgct gccccaggcg gcgagcgggg agagttcgag gaacggggtg tccgggtcga
     3901 gcagcagctc gacgcgttcg cgcgcggtca gcttgccgcg ttcgcggtgg cgccgcacgt
     3961 acttctcgcc gccgcccgcg agcgccttgg cgtgttcggc gtccagctcc gccagcttgc
     4021 cgagcatcgc ctcgcggtgc gcggcgtact cgggggcggc ggggtcgagc cgggtgggca
     4081 gcacggtcac agcagggcct ccgggaggtc gaggtggcgg gagcgcagcc actcccccac
     4141 ggccttggcc tgcgggtcga agcgcgcctg ggccgcgacg ccctcgccga gcaggccatc
     4201 gacggtgaag ttcagcgcgc gcaggttcgg cagcacgtgc cgggtgacgt ccagaccggc
     4261 ggtctccggg agcagctgcc ggaaccgctc gacggtcagc tcgtgcgcca gccagcgcca
     4321 ggcggcctcg gcgcgcaccc acacgccgac gttggcgctg ccgcccttgt ccccgctgcg
     4381 ggccccggcg accaggccga gcggggcgcg ccgcgacgcc ccccgggcga gcggttcggg
     4441 cagctccggt acgggtaggg cgtgttgcgg cccggcctgg acgggcgggg gcgcgacgcg
     4501 gtgccgcgtc ccgcctggca gcacggcggt gtgcgcggcc tcgccctgcg gtacggacgc
     4561 ggccgtgaag acgccgtagg gctggccccg ccccggcggc gcggtgacgt ggaacccggg
     4621 atagctagcc agcgccagct cgatcgctgc gccactgacc gcgcggccta cggcggcctc
     4681 gtcggcgtcc ttgaccacca gccgcagcag cgcgctcgcc tcttcctgca cctgggcatc
     4741 cgggtggtcg gtgcgggcga gcgtccagct gacgtgcgcg ggggcggcgg cgtcaagcgc
     4801 ctcgcgcaac tgctcgcgca cggcgtccgc cttcgcctcg atctccagcc cggtgaggac
     4861 gaacgtcacc tcgttgcggt agccgccgag ccgggtgagg cccaccttca gcgtggccgg
     4921 cggcggctcc ccgcgcacgc cgctgacccg cacccggtcc ggccccacct cggccagccg
     4981 cacggtgtcc aggcgcgcgg tgacatccgg acccgggtag cgcgggcccg ccgtctcgta
     5041 cagcagctgt gcggtgaccg tgcccacggt gaccgcgccg cccgtacccg ggtgcttggt
     5101 gatgacgcag ccgccgtccg cgtcgatctc cgcgagcggg aacccgtagg gcgggcccgg
     5161 cagctcgcgc cagaacgcgt agttgccgcc cgtcgcctgc gtgccgcact ccagcacgtg
     5221 cccggcgacg accgctccgg ccagcgcgtc ccagtcgtgc gcgccccacc cgtggtgcca
     5281 cgccgcgacg ccgctgacca gggccgcgtc cgacacacgc ccggtgatca ccacgtccgc
     5341 gcccgcctga agacacgcgg tgatgcccgc gccgccgagg taggcgttgg ccgtcagcac
     5401 gccctcaccc cagccgccgc gcgcggtgag gtcgtcaccc tccacgtgcg ccacccgcac
     5461 cggcaccccg agccgccccg ccagctcccg caccgcgtcc gccagcccgc ccgggttcag
     5521 ccccccggcg ttgctgacga gcttcacccc gcgttcgtgc gcgagcccca gagcgtcctc
     5581 caactgccgc aggtacgtgc gcgcgtaacc ccgggccggg tccttcagcc ggtcccggcc
     5641 caggatgagc atcgtcagct cggccaggta gtccccggtc accgcctcca gcggccctcc
     5701 ggtcagcatc tcccgcaatg ccgaggcccg gtccccgtag aaccccgacg cgttccccac
     5761 ccgtacgacc accacaccca cctcccacgc gaagaccgcc agcgtggcac cacccggaga
     5821 aacaatcaag catgcttgct ggttttttgg agctccttga ctccggaaca cattccggac
     5881 caaggtgccg gtatgtccac tcccaccgtg tcgttctccg acctctcgaa gaacgcgaaa
     5941 cgcgtggcag aggcggttga acacgcacaa cgcgtccaca tcacgcgccg cgacggagaa
     6001 gggctgttcc tcaccacgga gcaccacgat cgccagcgag aggagacggc cgacgtcacc
     6061 gcgcgtctcc tctcggccct cctcagcagc gacgaaggcg cccgagcggt cctcatcgcc
     6121 ctgccacagg tcttcccctg gacgcgccat ctgtcgccgg aggagatgcg tgagttcgtc
     6181 atcgacctcg tggacgccgc gcgcgatgcc accgacctcg acgtgcacgc gaacctgcac
     6241 cgcgtcatcg tcgagtggcg cgccaccgca cgcctcctgg ccgaccccga tctcgcggcg
     6301 cagctcacca agcccctgac atcttcacgc catcccaagg acaccgacac ctgagtacgg
     6361 ccagcgggcc acccgcagac cgcgcaccac gccccggcgc tgagccttcg catcgcctac
     6421 ggaaagatgc cccaggcgta cggcgaggcc ccgccaccag ccccgcgccg aacagacctc
     6481 actgggtgac ggcggccagt tcgtcacgga agcgcttcaa ctcgctggac gcgtacgtgg
     6541 cggaatccac gatctcagag acctctcgcg cctgctcccg gacacattcc ggggaggtca
     6601 gactgtactg cccggccatc gcctgctgcg ctgccgaaag cgctgtttcc atgcgggaca
     6661 cgggggcgat gtgatgcatg agcggaatgt cgcgttccgt tccgtcgtca gcgtgcaaag
     6721 tgaccgtgaa cgcgtagatc ttcggcaggc ttcccgcgta atcgcgctcc ggccccagcg
     6781 tgaacgcgat cctctcctgc gcgtggggcg gcacggtgta cttcatcttc cgctccagcg
     6841 tgaacgggac gtccttgccg tccgggacct tgatgtcgta cctggcctgg acctccgtgg
     6901 ggccagcccc gtacgcgcat cccgcctccc gcacgtgatc gaaacggaag tccgcccgcg
     6961 tgatcaggat cggattgtca ctgggattgc gaagcactag cgtcacctgg gaggcaggat
     7021 agtcctccct ctcctccacc ccatccggag taatccagtc agcgcggacg ttctcctccc
     7081 ggtccaggtc aaagtccacg atctccaact ccggcgcggg cggttcgggc tgaagacccg
     7141 gcaggagaag aaagacgagc cccagaaccg aggccaccaa cgccaccgcg ccccccgcca
     7201 ccgcgaggat gccctgcgga cgctggagga agggacgctc ggcggcccgc gccccctccg
     7261 tcgccacctc tccagccgaa ccctcgcggc ccccgtcacc cgttcccctg gccgcatccc
     7321 gcacgatgac caagcacccc cagttctctc ccagttgccc cgtgtgaacc tcacctccgg
     7381 caccgtaccc gagcgcggat tcacccagga agacaaaccg tcagaagacg agaccacccc
     7441 tggccaaccg catgcacggt cccggcaagg gtcagctacc ggagagcagc tgcggaacaa
     7501 ccggccgccc ggcgccaccc ccacgagacc caagccgtac acgccaggct ccagcgcacc
     7561 cacgatagga gcaagccccc gcagttggcc cacaactacc cactcagctc cgcaagccgc
     7621 ccctctcgaa cggatgtcag cagggtgtgg agcatgggcc gggacagacg cagcacgcgg
     7681 tctgcctccg tggactccct cagggccacg acctcaccat caccagcccg catctcgaca
     7741 cagttgtttc cctccgcgca gtaggaggac ttctgccagc cacagtcgtt cacgtcatga
     7801 cctctcagag aaccttcacg atgccaagga tgaagtctcg cgactcttca gccgtgagcg
     7861 ccagcgcctc caagcggtcg agcagttggc ggtacttctg caactgggct tccgcgtcga
     7921 ggagaacggg accatgggac tggtcaagtt gcactgtgtc cagctgcggc acggcaccat
     7981 gcgcataaaa gatggtctga cctgcaccgg ggaaccctcc tgcggtgaag ggcagcacca
     8041 gcaccgagag attctcccgc tcgctcacct ggagtatgtg ccgaagctgt gcccgagcga
     8101 caacgcggcc cccgaactgc atacgcaaag ccgcttcgtg gatgacggcg gtgtaaggga
     8161 ccgccttgtc ggcatacaga acagcttgcc gcttgatgcg ccacgaagtg cggtgctcca
     8221 tctcatgcgc gggcagttgg gggatgctat gcgcgaagac ggcacgcgca tggtcgagtg
     8281 tctgcaagag acccggcaag gtggccgtct gagcggtacg cattgccgct gcgtgatgtt
     8341 caagctcggc caggtcgaga agcccttgcg gtagcagccc ccggtactcc tcccaccact
     8401 ggcgtggcct tctgcccgtc atgctcgcca gcgcatcgat cagcgcttcg tccgcgcagt
     8461 cgtaattgca ggccagggtg cgcaggcgtg gggcgctgag gcccactcgg ccggtttcaa
     8521 tgttgctcat ccgagcctgg tcgatgccca ggagcgctcc agcctgcgtc gccgtgagac
     8581 cggcgcgctc tcgcagcttg cgcaactctg cgcccaagcg ctgctcgcga gccgtcggcg
     8641 cacttctagg cggcatctga ctccacactc tcctgcttcg ggcgccacca gcttacaagg
     8701 cacatctatt ttcctgaact agtagcgaag attccccatg gtcgctacgg tgtgaactga
     8761 cgcgatcacc ctccggggta ggtgtgatgc accgccctgc catgccagtt gaacgggagc
     8821 ttccatgaac ccgcccgcct tcaccgcgct tgccgctccg ccgccgttgg actccgcgga
     8881 ctggtggttc agcctgcggc tgtccaacga cccgcaagcc cccggtatcg cgcgaaccca
     8941 tctgcgcacg acgctcgacg cctacggcct cgacaccatc gtggacaccg ccgaattgct
     9001 caccagcgag gtggtgacca acgcccatcg gtacacagac gggccggtca ccgtgcgggc
     9061 gcagtacgtc ggcacgcgcc gccgcctgcg ggtaagtacg ggcgacgtca gcgcagtcgc
     9121 gccacgactc gcgtgcgcac tcccggccga cgagggagga cgcggactcc gcattctcga
     9181 cctctgtgcc ctctcttggg gctggttccc gctcagcgac tcccgggatg gattggctgg
     9241 aaaggtcgtc tggtatgagc tggcggcccc gtgaagcccg agcaggcgtg ggcttgacga
     9301 atcgaatggg gaaacgccac gccgaaccca ccgtcgttct tgcgggctgt cggctcgctg
     9361 tctgctggtc tgcgagcccg gcgatctttc cgaacggccc cgcgacctcg cgaaggtggc
     9421 cgagaaccgt tcaggggacg acgtcctgcg gctaccgtcc gtcgaacaca gaatggtgcg
     9481 ttcagcaagt ccagttcagc aactccgcac ttacaggaag actcgctgtg aaccttgctg
     9541 tcgccaaggc ccggtcgcgg catctggacg ccacgtcgcg aggcccggtc actcctaacg
     9601 tcgtggcgat cgactccggc gaactcatcg ccacggaggc ccattgcaag ggtggatatg
     9661 gcgcctgcac ctccagcgaa acctcatcat ccaccccacc agtccccggt gcggtcatcc
     9721 ggccgtgccg gaaccgccag caggcggtcc acgcagcggc ttcggccgcc caccccgaag
     9781 gagcacacat gcaagaggac gaattcgacc tggacatcag cattctggag tccggtgacg
     9841 ggtccgctgt cctggtcaac ctgaccgatg acgggtgcag tccgacctgc gaggggtcct
     9901 gcgccaccaa cgtggcctga caccgtcatc tcagccgttt cggcccgcac gacacatgcc
     9961 gtgcgggccg aaacggccag gccggaagag gtaaggactc atgaaccata gacaagacac
    10021 gctgtacgag tgcgcggaca cggcgctcgt acgggcggcc cggtataccc gactgtcgct
    10081 gccgccgtgg ccgaacgtga cttccgatgc cccggtgcag gtgcaccagt ggcatgcatg
    10141 gctcaaggcg gcgtgggcct tggacgaggt ctccgactct gtcgagcagg ccagcccctc
    10201 actcgcgcgg cacatggaca cacagtgcgc gatggtgggg ctgcccgagg cccggcaggt
    10261 gcgccggacc cttatctcgg tgatcaggta catccagcga atgactggca gagcgacacc
    10321 gaacggactc ttcgccgggg tcgccccggc cgggttcggg gaacggtccg agtacaagtg
    10381 gggtccttgg cacaaggcgg tagcgcgagt ggatgccgcg tggatgagcg acgtgatcac
    10441 cgagctggag gcgtgccccg acctgttgcg cagactgccg gtggtcgctg ccaacacagc
    10501 gttcgtgcgc ggggatcgac taatcgtccc ctatccggcg cgcttggcta cggccaagcc
    10561 gaccgcagag gtatcgctca ggttcacctc ggcggtgcaa acagccctgg gcgccgcccg
    10621 agcaccgatc gcgtgcggct tgctggccaa taaggtgagc tccaattttc ccgacgtacc
    10681 ggctgcccgg gtcatgaacc tcttgaccga cctgatgcga aacggggcac tcgtcagcag
    10741 cctgcacgca ccgtcctcca cgctcgacgc ccttgaccac gtcgtaggtg aactggacgc
    10801 catccacgct catgaggtgc cgtccatcgc gatcttgctg gacgatttac ggacggtacg
    10861 agacaacatg gcccagcaca atcgcgcgct cacaccagag gaggggcggc cgctgcgccg
    10921 cgagttgcgc cggaagatga ccgaggtagc cgacactgaa cacccgctgg cggtcgatct
    10981 caaggtggac tgctcgctca cgctgccgca cgcggtagcc cgcgaggccg agcaggcggc
    11041 caccgtactc gcgcggctca cgccagcacc cttcggtaca ccggggtgga aggagtacca
    11101 cacccgtttc ttcgagaagt acggaatcgg ctccctggtg ccgctgaggg atgtcgtaga
    11161 cccggatgtc ggcctggggt tccccgccgg atttttggac agcgagccag aagcgcgcga
    11221 agcactgaca cagcgggacc agcggctttt ggcgctcgca cagacggcag tccttgatgg
    11281 ccgcagcgag gtacagcttg acgaggagct gatcaccgaa cttgagagca gcgaacacaa
    11341 ccgggcgcag cttccaccac acctggagct tacgttccag atccatgcca cttccacgaa
    11401 gagccttgat catggtgact tcactctctc agcgatccgc ccctcacgcg gcatcggcac
    11461 cgtgggtggc cggttcctcc cactccttga gcccgaggac cacgctcggg cactcaccgt
    11521 cctgaaacgg ctcccgagca acacacctgg ggcactaccc gtgcaggtct ccctcccctc
    11581 gctcaatcgg gcgcatgccc aggtcacgcg ggtacctgag ctgctcccgg ccgtgatcag
    11641 cctcgccgag caccgggccg cagacgaacg caccgtcggc ctagacgacc ttgcggtggg
    11701 ttgtgaccga cgcaggctat acctcgcgtc gctctcacga cggtgcctag tggagccgca
    11761 cactgtgcac gctcttgacc tgcgcgtcca caccccgccc atggcgcggt tcctggtgga
    11821 gataagccgc gctcagtccg cgatcatcac tgcctttccc tggggagccg cctcggttct
    11881 gccctacttg ccccgcgtgc gccgtggccg gaccattctc gcgccagccc gctggctcct
    11941 ccgcgcggcg gacgtgccag cccggtccgc tgcgtggggg gaatggcacg agggcctgaa
    12001 cgaatggtgc gtgcgccgac ggatgccgaa gagggtagcc ctgaccgagg gagatcagct
    12061 tctccccctg gacctatccg agagtgccca tcgtgcggta ctacgtgccc acctcgccca
    12121 ggccgggacc gtagtactaa cggagacctc cgcccccggc gactggttcg acggccgcgc
    12181 tcacgaggtc gtcgtccccg tgacggcccg gcaacccacg cagtggccga ccgtggcgcc
    12241 cgtggccgtc aaccgcctcc tcacccgcga ccacggacac cttccgggca ccggcccgtg
    12301 gctcctggcc aaactgtatg gccatccgga gcgccaggct gaaattctgt cccggcacct
    12361 cccctacttg ttcgctgagt gggagacacc accgctgtgg tggtttatgc gccacggcga
    12421 tccccagtct cacctccgcc tgcgcgtcgc tgtcccggag gccgttgatg tgggacagct
    12481 cgtctcgcga atcggcggct ggggggcacg cttgcgccgt tccgggctgc tcaacgacat
    12541 acagttcgcc acgacctacc ccgagacggg ccgatgggga gctgggccac tcatgaatct
    12601 tgcggagaac atcttcgccg cagactcccg agccgttgcc gtgcagctct cccagccgga
    12661 ccgccccacc ccgtacgccc tgaccgccgc gaacttcgta tcccttgtca cggccttcac
    12721 cggcagcgtc acggaatcca tggagtggtt ggtcacgtac gggaagatca ccgatcctcg
    12781 acgactcgcc cggcatgtcc tcgccgaagc agtccgcctg gccgacccga ccgacgggtg
    12841 ggcggccctg cggagccacg cgggtgggcc agccatcacc gcggcctggg ccgagcgtga
    12901 ccaagccgtc gcgcgttaca gggctcgcct ccacgagtcc gacctcgatc cgcacctcgt
    12961 gctcgaatcg cttttgcatg cccaccacat ccgggctgtc ggcctggaca aggacaacga
    13021 acgcatgtgc gtgcgactgg ctcgcgccgc agctctggcc tggacagcac gtaaggggag
    13081 ccctcgtgga acagcgtgag accgctcggc tcgccgccgc agcgatcgcc gaccggctcg
    13141 cctccccgga ggacatgccc ggcatcgacc tcaagcaggg ctggtggccg cagtccctcg
    13201 cacacggcgc cgtcggcgtg gctctgctgc acatcgaacg cgcccgcgcc ggggaggggc
    13261 cgtggcaacg agtgcacgac tggctcactt gcgccgcagc gggcggagcc atcggcgggc
    13321 ctgacgctca tctctactac ggtgccccgg cactcgcctt cgctctgcat tccgcagcgg
    13381 atcggcccgg acggtacgct cgcgccctgg ccacgctcga cacccacgtg gccacactga
    13441 tccgtcagcg gctccaagtg gcacacacac gcatggaccg tggccgcgag ttccccgcac
    13501 tagccgagtt cgacacgatc cgcggactga gcggtcttgg cgctctgctc ctgcaccgtg
    13561 acacagaccc cgccctagtg gaaagcgtcc ttgcctacct ggtgcggttg acagagccgg
    13621 tcaagcacga cggagagctc ctacccggct ggtggagcca tctcggcccc tccggcacgc
    13681 gctccccgca cttccctgag ggccacagca acaacggagc cgcccatggc atcaccggcc
    13741 cacttgccct gctcgcgctg gccgcccggc gcggcatctc cgttgatggc cacaggacgg
    13801 cgatcaaacg catcttgtcc tggctggacc gctggcagca gaagggcgaa ggcggaccgt
    13861 ggtggccgta ctggatcacc cgtgatcaac tccggaccgg acgaaccagc ccaggcccat
    13921 tccgcccgtc ctggtgctat ggcaccgccg gatacgcccg cgcccagcag ctcaccgccc
    13981 tcgccacggg agatcacgac cgccagcgag cagccgaaat cgcactgctt ggggccatga
    14041 ccgaccccag ccaacgtgcg gccaccgtgg acctgtccct gtgccatggc ttcgccggac
    14101 tggcccacat cacccaactc gccgccgctg acgcgatcac ccccggcctt ggccggtgcc
    14161 tgcccgacct cctcgcgccg atgaccaata cgacccccga ccttctcgtc cgccctctgt
    14221 accgcccggc cgacggcaga gatatcggac ttctcgaagg tgctgcgggc acggccctcg
    14281 cactccactc cttctccgtc ggcagccccg ccccctcggg ctgggacgcc tgcttcctga
    14341 tcgcctgaac cggagcatca cacatgccac aagccgcatg gccgcaacgt ctcctcaagt
    14401 tccccgcatg gggcgaggcg gaggccacgt tcattgagca cctgctcccg gtgctgaccg
    14461 cgaacgatac cgagctgacc tactggtcgt tcctgcgaaa ggcccccgtc tggcgtctgc
    14521 gctaccgccc caccggtccg gcggcggcca agcgtctgga cctcgtcctg gaccagttgg
    14581 ttgccgccca tacgctcagc tcctggaccc cggggattta tgaaccggag gagacagcgt
    14641 tcggcggccc atccgccatg gacaccgcgc acatccactt ccacgaggac agccgacacg
    14701 tccttgaaca ttgagcggat ctcatcgtga ccggttcggg tgacggggtg cccgtgacgt
    14761 ggcgaagctc ctcga
//
