LOCUS       NZ_JAEVFI010000032     22438 bp    DNA     linear   CON 14-SEP-2024
DEFINITION  Streptomyces sp. JJ66 scaffold32_size147693, whole genome shotgun
            sequence.
ACCESSION   NZ_JAEVFI010000032
VERSION     NZ_JAEVFI010000032.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces sp. JJ66
  ORGANISM  Streptomyces sp. JJ66
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 147693)
  AUTHORS   Jose,P.A. and Jha,B.
  TITLE     Draft genome of Streptomyces sp. JJ66
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 147693)
  AUTHORS   Jose,P.A. and Jha,B.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-JAN-2021) Marine Biotechnology and Ecology Division,
            CSIR - Central Salt and Marine Chemicals Research Institute, G.B.
            Marg, Bhavnagar, Gujarat 364002, India
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 25-MAY-2017
            Assembly Method                   :: Velvet v. V 1.2.10
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 320.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_019303495.1-RS_2024_09_14
            Annotation Date                   :: 09/14/2024 03:51:48
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,515
            CDSs (total)                      :: 4,446
            Genes (coding)                    :: 4,340
            CDSs (with protein)               :: 4,340
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 61
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 31 of 106
            Pseudo Genes (incomplete)         :: 82 of 106
            Pseudo Genes (internal stop)      :: 3 of 106
            Pseudo Genes (multiple problems)  :: 9 of 106
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 09:22:12
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 119809
            Orig. end                         :: 142247
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JAEVFI010000032.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22438
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="terpene"
                     /region_number="1"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..22438
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22438
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="True"
                     /core_location="[10000:12438](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12438
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    847..860
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.11"
                     /tool="antismash"
     misc_feature    929..944
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.13"
                     /tool="antismash"
     misc_feature    1246..1259
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.47"
                     /tool="antismash"
     gene            1712..3031
                     /locus_tag="JJV70_RS19820"
                     /old_locus_tag="JJV70_19810"
     CDS             1712..3031
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006603910.1"
                     /locus_tag="JJV70_RS19820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJV70_19810"
                     /product="CHAD domain-containing protein"
                     /protein_id="WP_308294912.1"
                     /transl_table=11
                     /translation="MAPRHDLTADAARVPAPTRPASAPSPSGRRAPDRDGPGREARGGP
                     APRASALDRGGPERPGPVPPATGEAGPRREAHPPDEAGPRRAAHLPDEAGPRRAAHLPG
                     EAGPPPTGDPGAFHPAGTAAEVLSGYLHHQAGELLRALRQHEETAGSAERAADTAEAVR
                     LLRRAARRIAGTLHTFRRLLDPGWADHLATELNWLGELLAREYDYATRLDRLLAALHRL
                     AAPGEHTAPSAAPATRPGVGAARAGALLERQLTLLRTRAHSAALQALGSGRFHAVADAV
                     AVLASEAPLSADATAAPLPVLRPCLEHTHRRLTTAVDALPLGPGALAHTLTGTEDRYDG
                     SWHHVRLLLRHVRYAREVLGEESGLLDTAARHLHRHRDAADAAAAAAAAGRTPRIAPAT
                     AYALGVLHADQRHEVEAARLAFCRAWHPTTPAPDDAPAPR"
     gene            3216..3605
                     /locus_tag="JJV70_RS19825"
                     /old_locus_tag="JJV70_19815"
     CDS             3216..3605
                     /EC_number="3.6.-.-"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016644807.1"
                     /locus_tag="JJV70_RS19825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJV70_19815"
                     /product="NUDIX hydrolase"
                     /protein_id="WP_219049406.1"
                     /transl_table=11
                     /translation="MVRAAGCVLWRGARTGVEIALVHRPKWLDWSHPKGQLHDGEPAAT
                     AAVREVREETGMTCALGARLPTAHYRVTTGWKTVDYWLAEALSGTFTPSAEIDRVTWLP
                     PARAHLLLTHPRDRALLATALHLLH"
     gene            3704..3919
                     /locus_tag="JJV70_RS19830"
                     /old_locus_tag="JJV70_19820"
     CDS             3704..3919
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="JJV70_RS19830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="JJV70_19820"
                     /product="hypothetical protein"
                     /protein_id="WP_219049368.1"
                     /transl_table=11
                     /translation="MTEFLLLLGGLAAFAGLLIAMLLRRGNSRTTNPEGLCIEQDARDR
                     AHSARITHSAPNIRPQPTHISETHHR"
     gene            complement(4000..4446)
                     /locus_tag="JJV70_RS19835"
                     /old_locus_tag="JJV70_19825"
     CDS             complement(4000..4446)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015580387.1"
                     /locus_tag="JJV70_RS19835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJV70_19825"
                     /product="NUDIX domain-containing protein"
                     /protein_id="WP_219049369.1"
                     /transl_table=11
                     /translation="MSGQPAQPTIDTHLLVRDGDKLLLSQRGGPYGFGRWHMPSGKLDH
                     GESLTAGAARELFEETGLATDPASLRLVHVVHHRQSPAAEDRIGFFFEATVWEGEPVNK
                     EPEKCRALQWFTLDALPDDIIEYPGAGLHGYLRESGLLSEHGWR"
     gene            complement(4735..5466)
                     /locus_tag="JJV70_RS19840"
                     /old_locus_tag="JJV70_19830"
     CDS             complement(4735..5466)
                     /EC_number="2.1.-.-"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006133927.1"
                     /locus_tag="JJV70_RS19840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJV70_19830"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_257574257.1"
                     /transl_table=11
                     /translation="MDRWITAVHGGTLRRADPAPLAVDLGYGAAPWTAVELLTRLRHAR
                     GDLHLTGLEIDPARVAAAQPYARPGLTFARGGFEIPLPARPLLIRAANVLRQYPEAEVP
                     AVWSRLCSRLAPGGLLVDGTCDEIGRRHVWIALGPEGPRTVTFAARLATLARPSDLAER
                     LPKALIHHNVPGRPVHTFLTAFDAAWAAAAPYAPLSARQRWLHTARTLAADWPVLDTPT
                     RWRHGELTVPWTTLAPPGFPA"
     gene            5701..7017
                     /gene="mshA"
                     /locus_tag="JJV70_RS19845"
                     /old_locus_tag="JJV70_19835"
     CDS             5701..7017
                     /EC_number="2.4.1.250"
                     /GO_function="GO:0008375 - acetylglucosaminyltransferase
                     activity [Evidence IEA]"
                     /GO_process="GO:0010125 - mycothiol biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="mshA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1045: glycosyl transferase group 1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018519653.1"
                     /locus_tag="JJV70_RS19845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJV70_19835"
                     /product="D-inositol-3-phosphate glycosyltransferase"
                     /protein_id="WP_219049371.1"
                     /sec_met_domain="Glycos_transf_1 (E-value: 2.6e-34,
                     bitscore: 111.6, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSAYVTRLGRRLGLPRRARRVAMLSVHTSPLHQPGTGDAGGMNVY
                     IVELARQLARLGTEVEVFTRATTGGLPPTVELAPGVLVRHVDAGPYEGLKKEELPAQLC
                     AFTHGVMRQWARHRPGYYDLVHSHYWLSGHVGWLAAQRWGVPLVHAMHTMAKVKNAALA
                     EGDTPEPAARVIGETQIVRAADRLVANTAEEAEELRRHYDADPDRTAVVHPGVNLTRFT
                     PGDGRAAARTRLGLPQDAFIPLFAGRIQPLKAPDVLLRAVRVLLDADPALRGRLVVPVV
                     GGPSGTGLAKPEGLQKLAARLGIADVVCFRPPQDQEALADWYRAASVLVMPSYNESFGL
                     VAIEAQASGTPVVAAAVGGLPVAVRDGVTGYLVAGHDPADYARALRRLADEPERVTRMG
                     AAAAAHARAFGWAAAAHRTAEVYADALAARPGRLRSLHV"
     gene            7010..7564
                     /locus_tag="JJV70_RS19850"
                     /old_locus_tag="JJV70_19840"
     CDS             7010..7564
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013002624.1"
                     /locus_tag="JJV70_RS19850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJV70_19840"
                     /product="YbjN domain-containing protein"
                     /protein_id="WP_219049372.1"
                     /transl_table=11
                     /translation="MSDASAVIEQTLADAELEWESPKPGTYVVTLPGTRKLSTTCQLIV
                     GAHSLSVNAFVIRNPDENHAGVHRWLLERNTRLYGVSYAIDQLGDIYLVGRLPLVSVTS
                     EEIDRVLGTVLENADGSFNHLLELGFAGAIKREYAWRTSRGESTRNLAAFTRLTGADGA
                     SGDPADRDTADGHRAAGEDGP"
     gene            7793..8218
                     /locus_tag="JJV70_RS19855"
                     /old_locus_tag="JJV70_19845"
     CDS             7793..8218
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012998551.1"
                     /locus_tag="JJV70_RS19855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJV70_19845"
                     /product="DUF6003 family protein"
                     /protein_id="WP_219049373.1"
                     /transl_table=11
                     /translation="MTDSAHLFLVPESAEAHVGARLAEVGELEYSQSSAVLGWLDAHGV
                     RADSDRLRLLPPEARGSVPAGAEALPVPLSEEELDRLRTACAAPDVAELERELRAYRET
                     TEDRERLVTRALAGGVPPHRIAELTGLDPADIAHAAS"
     gene            8435..9418
                     /locus_tag="JJV70_RS22965"
     CDS             8435..9418
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006601672.1"
                     /locus_tag="JJV70_RS22965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_257574229.1"
                     /transl_table=11
                     /translation="MWERNTVLAEAFCTSDDRVREAQTVLDEAQAERTRMLAAFAVTVG
                     NDGAVADLMGLHEREVRVARRTVGKEDARTMASGLLTPSPGPDPDSAPGTEEQAAPEPV
                     PGGVTLNDLLQQPHADVHVPRPRVEATEPTGPEPQPVAPHPVAHNPYATPAAPAQPYAA
                     QQHAAQAYTTQAHAAHPSAAHPHAAHPHAAHPLTHQPFTAPERPEPTEPPGTRSPGPSA
                     PRSEAAREAEAWSSSMDSVLVWSWQSGVDLQFVAEELGLDLRALLVRVQTLAAEGRLSL
                     HAPPPPASSDTAGRHRRRQGSGQPEEYPYVTTPTDVLGPFTTPAYR"
     gene            10001..11080
                     /locus_tag="JJV70_RS19865"
                     /old_locus_tag="JJV70_19855"
     CDS             10001..11080
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003957287.1"
                     /locus_tag="JJV70_RS19865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJV70_19855"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_219049374.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 1.8e-50, bitscore:
                     164.8, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTALPEGAAPLDLPHIRTRVDTVLADFLRAKTRSAAARAWPEEIT
                     TTLHGFLSAGGKRLRPTLCVVGWHAGGGGSPAPASVLRVAAALEMFHAFALIHDDIMDH
                     SLTRRGQPTAHRALAAFHQGRGDADQLGVHSAILLGDLALVWSDELLHAADLTPTQLAA
                     TLDIVDLMRTELVYGQYLDLCATGHPTDDVERCRKIVRYKTVRYTLRHPLAIGATLADA
                     EPAVHAALDAYAHPVGEAFQLADDLLGVYGHPDETGKSRLDDLRDGKHTLLTALALRHA
                     SPAERHTLRTLLGAPGLTDADADRVRAILDATGAPTRVADRIRACRRQAEHLLDQAPFP
                     PPATTTLRHIAHLCTVRTA"
     gene            11317..12438
                     /locus_tag="JJV70_RS19870"
                     /old_locus_tag="JJV70_19860"
     CDS             11317..12438
                     /GO_function="GO:0010333 - terpene synthase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0046246 - terpene biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF040195.4"
                     /locus_tag="JJV70_RS19870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJV70_19860"
                     /product="terpene synthase family protein"
                     /protein_id="WP_219049375.1"
                     /sec_met_domain="T1TS (E-value: 1.1e-61, bitscore: 202.7,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAPAPQHDDATPAEPSPLHLHVPPVYCPIPTTRHPRTDEFRDNGA
                     NWMADHGLCPDDQQRDRVIGTRSAEWVGDAVPDGIPDRMQIWADWFYLMFAVDDFHDEY
                     PNWHQAIDFSARLACTIANPDAQAFPADNPFAAPLRDVARRYHEHATPTQLNRWTQHHR
                     AWLLAVCRQVALGHAGIVLDLNDFVTMRLHTCAGEATYAPMEMVVDAEVPEAEMSSPAV
                     RALREMAVFVAAWDNDLGSYGKEWWLSQQNSVRPDPVPGNIVDILLRGTGCTLEQALTR
                     SIAMRDRAMVRFLRPREQVLPQASEELALFLNYLGTGISGNITAAFTSERYTLPDPAHP
                     DALKVTYSVRTEAPPDADQPLPLPATAWWWDDL"
     gene            complement(12634..12900)
                     /locus_tag="JJV70_RS19875"
                     /old_locus_tag="JJV70_19865"
     CDS             complement(12634..12900)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004939033.1"
                     /locus_tag="JJV70_RS19875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJV70_19865"
                     /product="DUF4235 domain-containing protein"
                     /protein_id="WP_219049376.1"
                     /transl_table=11
                     /translation="MNAAKLAYKPFGLLAGIASGAVAGAVFQQVWKRLGHADDAPDATD
                     PHRGWPEILLAAALQGAIFAAVKATVNRGGATAVHRLTGTWPD"
     gene            complement(12897..13346)
                     /locus_tag="JJV70_RS19880"
                     /old_locus_tag="JJV70_19870"
     CDS             complement(12897..13346)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF023697.5"
                     /locus_tag="JJV70_RS19880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJV70_19870"
                     /product="DUF3618 domain-containing protein"
                     /protein_id="WP_219049377.1"
                     /transl_table=11
                     /translation="MTEPAPSSEVTPEELRAQAEHTREELGVTIEALAGKADVKAQARQ
                     KATELTGQAKVKAGQAKAKAAQLAQTVREKAPEPVRAKAAQATDQLTGTTRTLTAKAQA
                     NTPASVQEKAALAGTAARDHRGLLVGGLAAALAFVLLTRRRKGRR"
     gene            complement(13343..13762)
                     /locus_tag="JJV70_RS19885"
                     /old_locus_tag="JJV70_19875"
     CDS             complement(13343..13762)
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018381583.1"
                     /locus_tag="JJV70_RS19885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJV70_19875"
                     /product="phage holin family protein"
                     /protein_id="WP_219049378.1"
                     /transl_table=11
                     /translation="MDSSPKTPPGPLREATAADLVKQASEQLTQLVRTELRLAQVEMKQ
                     KGKRFGLGGGLFGAAGLVAVFALQAAVATVIIALALVWPPWLAALVVTFALSALAAVLA
                     AAGKKEVAQAGAPAPQEAIDNVKTDVAHIKESAQR"
     gene            14079..14897
                     /locus_tag="JJV70_RS23575"
                     /old_locus_tag="JJV70_19880"
                     /pseudo=""
     CDS             14079..14897
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004942023.1"
                     /locus_tag="JJV70_RS23575"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="JJV70_19880"
                     /product="DUF72 domain-containing protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MAVLVGTSGWQYRDWRGVLYPPGLPQRLWLEGYARRFPTVESNNA
                     FYRLPAPETFAAWRERTPPGFVMALKASRFLTHIRRLREPEEPVRRLLAHAGPLAERHG
                     PVLLQLPPTLPELLPSAPPFRVEVQGILASAARRGAAPLLRSPCPTTELSDLPPDGREV
                     KPVETW"
     gene            14989..15747
                     /locus_tag="JJV70_RS19895"
                     /old_locus_tag="JJV70_19885"
     CDS             14989..15747
                     /EC_number="5.4.2.11"
                     /GO_function="GO:0004619 - phosphoglycerate mutase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1101: phosphoglycerate mutase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003953499.1"
                     /locus_tag="JJV70_RS19895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJV70_19885"
                     /product="phosphoglyceromutase"
                     /protein_id="WP_219049379.1"
                     /transl_table=11
                     /translation="MADATYKLILLRHGESEWNAKNLFTGWVDVNLTDKGETEAVRGGE
                     LMADAGLLPDVVHTSVQKRAIRTANLALEACDRHWIPVHRSWRLNERHYGALQGKDKAQ
                     TLAEFGEEQFMLWRRSYDTPPPVLEDGAEWSQADDPRYAMIPPELRPRTECLKDVVHRM
                     MPYWYDSVVPDLSTGRTVLLAAHGNSLRALVKHLDGVSDADIAGLNIPTGIPLLYELDA
                     AFHPTNPGGTYLDPEAAKAAIEAVKNQGKK"
     gene            complement(16155..16931)
                     /gene="phoU"
                     /locus_tag="JJV70_RS19900"
                     /old_locus_tag="JJV70_19890"
     CDS             complement(16155..16931)
                     /GO_process="GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /GO_process="GO:0030643 - intracellular phosphate ion
                     homeostasis [Evidence IEA]"
                     /GO_process="GO:0045936 - negative regulation of phosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /gene="phoU"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019355198.1"
                     /locus_tag="JJV70_RS19900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJV70_19890"
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="WP_257574230.1"
                     /transl_table=11
                     /translation="MRDAYHEELDAIGDSLVEMARLVGSAIGRATTAMLDADLKLAESV
                     IANDDKVDDLQRSLESKAIQLLARQQPVATDLRIVVTSLRMSADLERSGDLAQHVAKVA
                     RLRFPDSAVPRDLQATILEMGQLAQRLMAKAAEVLITKDVELALQLEHDDDRMDDLHRT
                     LFQHLMDDRWKHGIETAVDVTLLGRYYERFADHAVSVARRVVYLVTGDYADELDPAAAV
                     AATETAPAAASAATSSQAPVTPDSPASSPADEPASD"
     misc_feature    complement(16891..16905)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.68"
                     /tool="antismash"
     misc_feature    complement(17172..17187)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 20.62"
                     /tool="antismash"
     gene            17261..18571
                     /locus_tag="JJV70_RS19905"
                     /old_locus_tag="JJV70_19895"
     CDS             17261..18571
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014177581.1"
                     /locus_tag="JJV70_RS19905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJV70_19895"
                     /product="cell wall metabolism sensor histidine kinase
                     WalK"
                     /protein_id="WP_219049380.1"
                     /transl_table=11
                     /translation="MDVNAAVAAVAAIAGVCTGAIAVLAFRWSEREQARPTRSSLHTEP
                     VLPPGVDTVLSVLRSSAVVLDEADAVVKASSAAYALGLVRGGRLAVEPMLQMARETRRD
                     GEIRQVELDLARRGRGDALAVSARVAPLGSRLVLLLVEDLTEARRIEAIRRDFVANVSH
                     ELKTPVGALSLLSEAVLDASDDPEAVRRFAGRMEHEATRLTSLVQELIDLSRVQNDNPM
                     EDSEPVSVEELVGEAIDRCRQGADAKQITMAAGGVEELHVFGHRGQLAAALGNLVENAV
                     NYSPPRTRVGIAARRVPAPGGDMIELAVTDQGIGISERDRDRIFERFYRVDPARSRATG
                     GTGLGLAIVKHVAASHGGEVTVWSAEGQGSTFTLRLPEAGSAREKAEESRRSRTRLSGA
                     LHKPGEYVGPDDGEEADIVDPVEARPREPHASPEVLP"
     misc_feature    17263..17274
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: strong, score: 20.58"
                     /tool="antismash"
     gene            18568..19248
                     /locus_tag="JJV70_RS19910"
                     /old_locus_tag="JJV70_19900"
     CDS             18568..19248
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008410337.1"
                     /locus_tag="JJV70_RS19910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJV70_19900"
                     /product="response regulator transcription factor"
                     /protein_id="WP_219049381.1"
                     /transl_table=11
                     /translation="MTRVLVVEDEESFSDALSYMLRKEGFEVAVAATGPDGLDEFERNG
                     ADLVLLDLMLPGLPGTEVCRQLRSQSSVPVIMVTAKDSEIDKVVGLEIGADDYVTKPFS
                     SRELVARIRAVLRRRGEPEETVPAALEAGPVRMDVDRHVVTVSGGKVDLPLKEFDLLEM
                     LLRNAGRVLTRMQLIDRVWGADYVGDTKTLDVHVKRLRAKIEPDPGAPRYLVTVRGLGY
                     KFEP"
     gene            complement(19354..20049)
                     /locus_tag="JJV70_RS19915"
                     /old_locus_tag="JJV70_19905"
     CDS             complement(19354..20049)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019523959.1"
                     /locus_tag="JJV70_RS19915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJV70_19905"
                     /product="DUF461 domain-containing protein"
                     /protein_id="WP_219049382.1"
                     /transl_table=11
                     /translation="MSSSRSSLRRGAVAAVLALSSSALVGCGAGVNAATNEIRPDHAYV
                     TQGDIEIQNISVVTTEDGEGPAAITARIFNEGTEDETLEAITFASDDGSGEAQLSPAEG
                     GELTVPAGGHLMLGGEGNAAAVIEDAAAQGITDGAAQPLTFELSETGAIEVPALVVPAS
                     QLTYSEWGPSQEPTGSPEGAQSPDDGQTPGEEAPGEEQAPDDAEAPAGAETPAGTEAPE
                     TAQTPGEAE"
     misc_feature    complement(20318..20332)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.65"
                     /tool="antismash"
     gene            20639..21121
                     /locus_tag="JJV70_RS19920"
                     /old_locus_tag="JJV70_19910"
     CDS             20639..21121
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014136563.1"
                     /locus_tag="JJV70_RS19920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJV70_19910"
                     /product="CarD family transcriptional regulator"
                     /protein_id="WP_219049383.1"
                     /transl_table=11
                     /translation="MTFKVGDTVVYPHHGAALIEAIETRQIKGVDKTYLVLKVAQGDLE
                     VRVPAENAELVGVRDVVGQDGLERVFDVLRAPYAEEPTNWSRRYKANLEKLASGDVIKV
                     AEVVRDLWRRERERGLSAGEKRMLAKARQILVSELALAENTNEDKAEALLDEVLAS"
     gene            21529..22320
                     /gene="ispD"
                     /locus_tag="JJV70_RS19925"
                     /old_locus_tag="JJV70_19915"
     CDS             21529..22320
                     /EC_number="2.7.7.60"
                     /GO_function="GO:0050518 - 2-C-methyl-D-erythritol
                     4-phosphate cytidylyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0019288 - isopentenyl diphosphate
                     biosynthetic process, methylerythritol 4-phosphate pathway
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="ispD"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_3"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006139062.1"
                     /locus_tag="JJV70_RS19925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJV70_19915"
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="WP_219049407.1"
                     /sec_met_domain="NTP_transf_3 (E-value: 8.8e-13, bitscore:
                     42.2, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTAALPRTAPSRTAPPAARTAAVIPAAGRGVRLGPGAPKALRAL
                     GGTPLLVHAVRAVARAREVGLVVVVAPPQAAAEVRHLLDAHPLPAAPAAQGADVVVVPG
                     GATRQESVRRGLDALPGEVEIVLVHDAARPLVPADTVDAVAAAVRAGAPAVVPALPLTD
                     TVKEVEPQAAGAPEPVISTPARARLRAVQTPQGFQRAVLAEAHAAFAGAGEGATDDAGM
                     VERLGQPVVVVPGHEEAFKVTRPLDLVLAEAVLTRRRADGY"
ORIGIN
        1 tgggcggagc tgaccgagaa ggagcaggcc cgcctgttca gcctgttccg gcaccagatc
       61 tacccggtgc tcaccccgct ggccgtggac ccggcgcacc ccttccccta catctccggc
      121 ctctccctca acctcgccgt tgtcgtgcgc aacccgatca gcgggcacaa ccacttcgcc
      181 cgcgtgaagg tgccgccgct gctggcccgg ttcctggagg cgtccccgca gcggtacgtg
      241 ccgctggagg acgtcatagc ggcgcacctg gaggagctgt tccccgggat ggaggtgctg
      301 gcgcaccaca tgttccgcgt cacccgcaac gaggacctgg aggtcgagga ggacgacgcg
      361 gagaacctgc tccaggcgct ggagaaggaa ctgatgcgcc gccgcttcgg gccgccggtg
      421 cggctggagg tcgaggagtc catcgacccg tacgtgctgg acctgctggt gcgcgagctg
      481 aaggtctccg acgcggaggt ctacccgctg cccggcccgc tggacctggc gggcctgtcc
      541 gcgctcgtcg gccgggtaga gcgtccggag ctgcgcttcc cgaaatacat cgccggtacg
      601 caccgcgacc tggccgaggt ggagtccgcc tccgcgcccg acgtcttcgc ggccctgcgc
      661 gaacgcgatg tgctcctgca ccacccctac gactctttct ccacctccgt gcaggcgttc
      721 ctggagcagg ccgccgccga cccggacgtg ctggccatca agcagacgct ctaccgcacc
      781 tccggtgact caccgatcgt ggacgcgctg atcgacgccg ccgagtccgg caagcaggtc
      841 ctcgttctgg tcgagatcaa ggcgcggttc gacgagcagg ccaacatcaa gtgggcgcgc
      901 aagctggagg aggcgggctg ccacgtcgtc tacggtctgg tcggcctgaa gacgcactgc
      961 aagctctccc tcgtcgtgcg gcaggagggc gagcagctgc gccgctacgc ccacgtcggc
     1021 accggcaact accaccccaa gacggcccgc ctctacgagg acgtcggcct gctgacggcc
     1081 gaccccgagg tcggcgcgga cctgtccgac ctgttcaacc gcctctccgg ctactcccgc
     1141 cgggagacct accggcggct gctggtcgcc cccacctcgc tgcgcgacgg gctggtcgcg
     1201 cgcatcgcca gggaggtcgc ccaccaccgc gcgggacggc ccgccttcgt ccggatcaag
     1261 gtcaactcga tcgtggacga gaccgtgatc gacgcgctct accgcgccgc gcgcgccggg
     1321 gtgcccgtgg acctgtgggt acgcggcatc tgcgccgtgc gtcccggcgt gcccgggctg
     1381 agcgagaaca tccgcgtccg ctcgatactg ggccggttcc tggagcactc gcgcgtcttc
     1441 gcgttcggca acggcggcga gccggaggtg tgggtcggca gcgctgacct catgcaccgc
     1501 aacctcgacc ggcgtatcga ggcgctcgtc cgcgtcaccg accccggaca ccgcgcggcg
     1561 ctcaaccggc tgctggagac cggcgtggaa gacaccaccg cctcctggca cctcggcccc
     1621 gacggcgact ggacccggca cgccaccgac gccgacggca ggccgctgcg caacgtacag
     1681 gaaacgctca tcgacgcccg gaggcgccga cgtggcccca cgacatgacc tgacggcgga
     1741 cgccgcccgg gtccccgccc ccacccgccc cgcctcggca ccgtccccgt ccggccgccg
     1801 cgccccggac cgcgacgggc caggccgcga ggcgcggggc ggtcccgcgc ctcgcgcctc
     1861 ggcgctggat cgcggcgggc cggagcgtcc cgggccggtg ccgcccgcca cgggcgaggc
     1921 tggcccccgg cgcgaggctc accccccgga cgaggctggc ccccggcgtg cggcccacct
     1981 cccggacgag gctggccccc ggcgtgcggc ccacctcccg ggcgaggctg gcccgccgcc
     2041 gaccggggac ccgggcgcct tccaccccgc cgggacggcc gccgaggtgc tctccggcta
     2101 cctgcaccac caggcgggcg aactgctgcg ggcgctgcgc cagcacgagg agacggcggg
     2161 cagcgcggaa cgggccgccg acaccgccga ggccgtccgc ctgctgcgcc gcgccgcccg
     2221 ccgcatcgcg ggcaccctgc acaccttccg ccgcctgctc gacccgggct gggccgacca
     2281 cctggccacc gaactgaact ggctgggcga actgctggcc cgcgaatacg actacgccac
     2341 ccgcctggac cgcctgctcg ccgccctgca ccggctcgcg gcacccggcg aacacaccgc
     2401 gccctccgct gccccggcca cccgccccgg cgtcggcgcc gcccgcgccg gtgccctgct
     2461 ggagcgtcag ctcaccctcc tgcgcacccg cgcccactcc gccgccctac aggcactggg
     2521 ctccggccgg ttccacgccg tcgccgacgc ggtggccgtg ctcgcctccg aagcaccgct
     2581 gtccgccgac gctaccgccg ccccgctccc cgtcctgcgc ccctgcctgg agcacaccca
     2641 ccgccgcctc accaccgccg tggacgccct gccgctcggc cccggcgccc tggcccacac
     2701 cctcaccggc accgaggacc gctacgacgg ctcctggcac cacgtccgcc tgctcctgcg
     2761 ccacgtgcgg tacgcgcggg aggtgctggg agaagagagc gggctgctcg acaccgccgc
     2821 gcgccacctg caccggcacc gcgacgccgc cgacgccgcc gctgcggccg ccgccgctgg
     2881 ccgcaccccg cgcatcgccc cggccaccgc ctacgcgctc ggcgtcctgc acgccgacca
     2941 gcgccacgag gtggaggccg cccgcctcgc cttctgccgc gcctggcacc ccaccacccc
     3001 ggcccccgac gatgcccccg ccccgcgctg acgccgccgc cggagatgcc gacgccgccc
     3061 ggggcaacgc cgccgccccg ggcaacggcg ttgcccgggc tgacggcgcg aacggaactg
     3121 acggggcggc ccgggtcggc ctccgtggcc gggctgacgt cggcggcccg ggtgccgacg
     3181 cggaccaggg caccgaggcg gagtggggtg agggcgtggt ccgggccgca ggctgcgtgc
     3241 tgtggcgcgg cgcccgcacc ggcgtcgaga tcgccctcgt ccaccgcccg aagtggctcg
     3301 actggtcgca ccccaaaggc cagctccacg acggggagcc agccgccacc gccgccgtcc
     3361 gcgaggtgcg cgaggaaacc ggcatgacgt gtgccctcgg cgcccgcctt cccaccgccc
     3421 actaccgcgt caccaccggc tggaaaaccg tcgactactg gctcgccgaa gccctgtccg
     3481 gcaccttcac cccgtccgcc gagatcgacc gcgtcacctg gctcccaccc gcccgagccc
     3541 acctcctcct cacccacccc cgcgaccgcg ccctcctggc caccgcgctg cacctgctgc
     3601 actgaccacc cgcgaacgtt gccgcgacca ggcaatgaca cccaccctcc accgctccta
     3661 cccttccggt accggcaggc acacacagga ggtgtacgac cccatgaccg agttccttct
     3721 cctcctcggc gggctggcgg cgttcgccgg gctgctcatc gcgatgctcc tgcgccgagg
     3781 caactcccgc accaccaacc ccgagggcct gtgcatcgaa caggacgccc gcgaccgcgc
     3841 ccactccgcc cgcatcaccc actccgcacc caacatccgc ccccagccca cccacatcag
     3901 cgaaacccac caccgctgac gcgaacggtc ctatggcccc ggaaaacccg tcggggtcag
     3961 ggcgcaccgg gcggtgccag gtggccgggg gcacggctgc tagcgccagc cgtgctcgga
     4021 gaggaggccg gattccctca ggtagccgtg gagtccggct ccggggtact cgatgatgtc
     4081 gtcgggcagc gcgtccaggg tgaaccactg gagcgcccgg cacttctccg gctccttgtt
     4141 gaccggctcg ccttcccaca ccgtggcctc gaagaagaag ccgatccggt cctcagcagc
     4201 ggggctttgc cggtggtgca ccacgtggac caggcggagg ctggccggat cggtggcgag
     4261 ccccgtctcc tcgaacagct cccgggcggc tccggcggtc agggactccc cgtggtcgag
     4321 tttgcccgag ggcatgtgcc acctgccgaa gccgtacggt ccgccgcgct gggagagcag
     4381 gagcttgtcc ccgtcccgga cgagcaggtg ggtgtcgatg gtgggctgtg ccggttggcc
     4441 gctcatgggt cctggggtgt gggagttggg tggtgcgtcc gacgttatcg gctgcggcga
     4501 gacggcgtgg gcgatccggg cgcgcggtca gcatcgcggg gagaccgggg agcgaaacgt
     4561 cggcgttgca acggaggaag gcgccccgtg ggcgggcggc ggttccggca gttggccagg
     4621 ggtgggtctg tggtgatgac aagaccgcgc ggttcgttgt ggagcatcgt ggcggcgtga
     4681 gaaccgcgcg agcgtggggc gtgcgtcgcg ggcggagaag ggcggaaccg gggcctacgc
     4741 cgggaagccc gggggtgcga gggtggtcca ggggacggtg agttcgccgt ggcgccagcg
     4801 ggtgggggtg tcgagtacgg gccagtcggc ggccagggtg cgggcggtgt ggagccagcg
     4861 ctggcgggcg ctgagcggag cgtagggggc ggcggcggcc caggcggcgt cgaacgcggt
     4921 gaggaaagtg tgcaccgggc ggccggggac gttgtggtgg atcagcgctt tcggcaggcg
     4981 ttcggccagg tcggaggggc gggcgagggt cgccaggcgg gcggcgaagg tgacggtgcg
     5041 cgggccttcg gggccgagcg cgatccacac gtggcggcgg ccgatctcgt cgcaggtgcc
     5101 gtccacgagc agaccgccgg gcgcgaggcg ggagcacagg cgggaccaga cggcggggac
     5161 ctcggcctcc gggtactggc gcagcacgtt cgcggcgcgg atcagcaggg ggcgggcggg
     5221 gagcgggatc tcgaagccgc cgcgggcgaa ggtcaggccg ggacgggcgt agggctgggc
     5281 ggcggcgacg cgggccgggt cgatctccag cccggtgagg tgcaggtcgc cgcgagcgtg
     5341 gcgcagccgg gtcagcagct cgacggccgt ccagggggcg gcgccgtagc cgagatcgac
     5401 ggcgagcggc gcggggtcgg cgcggcgcag tgtgccgccg tggacggcgg tgatccagcg
     5461 gtccatgcgg cgcagccggt tggggttggt cgtcccgcgc gtgaccgtgc cgaccgggcg
     5521 ggggacgggg cgaggggcgg gcacggtgga ccagggtacg ccggacccgg ggacgccgga
     5581 cccgggtacg ggccgtaggt cacggttggg caaagtggga agacgcgggc ggagcgaggc
     5641 gttccgtctt acggaatcgc ggcggcccca gcccgcaccc cggcagcgcg aggaggacac
     5701 gtgagcgcgt acgtgacgcg gctcggacgt cggctcggcc tcccacgcag agcgcgccgc
     5761 gtcgccatgc tcagcgtgca cacctcgccg ctgcaccagc ccggcacggg cgacgcgggc
     5821 ggcatgaacg tctacatcgt ggagctggcc cggcagctgg cgcggctggg caccgaggtg
     5881 gaggtgttca cccgggcgac gacgggcggg ctgccgccga cggtcgagct ggcgcccggg
     5941 gtgctggtgc ggcacgtgga cgccggcccg tacgaggggc tgaagaagga ggagctgccc
     6001 gcccagctgt gcgccttcac gcacggcgtc atgcggcagt gggcgcggca ccggccgggc
     6061 tactacgacc tggtgcactc gcactactgg ctgtcgggcc acgtcggctg gctggccgcg
     6121 cagcgctggg gtgtgccgct ggtgcacgcg atgcacacca tggccaaggt caagaacgcg
     6181 gcgctggccg agggcgacac cccggaaccg gccgcccgcg tcatcggcga gacgcagatc
     6241 gtgcgcgccg ccgaccggct ggtggccaac accgccgagg aggccgagga actgcgccgc
     6301 cactacgacg ccgacccgga ccggaccgcc gtcgtccacc ccggcgtgaa cctcacccgc
     6361 ttcacgcccg gcgacgggcg ggcggcggcc cgaacccggc tcgggctgcc gcaggacgcg
     6421 ttcatccccc tgttcgccgg ccgcatccag ccgctgaagg cgccggacgt gctgctgcgc
     6481 gccgtgcgcg tcctgctgga cgccgacccg gcgctgcgcg ggcgcctggt cgtgccggtg
     6541 gtgggcggcc cctccggcac cgggctcgcc aagccggagg ggctgcagaa gctcgcggcg
     6601 cggctgggca tcgccgacgt cgtgtgcttc cggccgccgc aggaccagga ggcgctggcc
     6661 gactggtacc gggcggcgag cgtgctggtc atgccgtcgt acaacgagtc cttcgggctg
     6721 gtggccatcg aggcgcaggc gtcggggacg ccggtggtcg cggcggccgt gggcgggctg
     6781 ccggtggccg tccgggacgg ggtgacgggc tacctcgtcg cggggcacga cccggccgac
     6841 tacgcccgcg ccctgcgccg cctcgccgac gagcccgagc gcgtcacccg gatgggcgcg
     6901 gccgccgccg cgcacgcgcg ggccttcggc tgggccgccg ccgcccaccg caccgccgag
     6961 gtgtacgccg acgcgctcgc cgcccggccc ggtcgcctac gatcgctgca tgtctgacgc
     7021 ctccgccgtg atcgagcaga cgctcgccga cgccgaactg gagtgggagt cgccgaagcc
     7081 gggcacgtac gtggtcacgc tgccgggcac ccggaagctg tccacgacgt gccagctgat
     7141 cgtcggcgcc cactcgctgt ccgtgaacgc cttcgtcatc cgcaacccgg atgagaacca
     7201 cgcgggcgtg caccgctggc tgctggaacg caacacccgg ctgtacgggg tgagttacgc
     7261 catcgaccag ctgggcgaca tctacctcgt cggccgcctg ccgctagttt ccgtcacctc
     7321 cgaggagatc gaccgcgtcc tgggcaccgt gctggagaac gccgacggtt ccttcaacca
     7381 cctgctggag ctgggcttcg ccggggcgat caaacgcgag tacgcctggc gcacctcccg
     7441 cggcgagtcc acccgcaacc tggcggcgtt cacccgcctg accggcgccg acggcgcgag
     7501 cggcgacccg gcggacaggg acacggcgga cggccaccgc gctgccggag aggacggccc
     7561 gtaggggcca accgctgacc accaccccgg cgtggcacgc cgcgctgggc tggcccgtcg
     7621 agatcgagct agaccacccc tccgtaacgc acgggtgcag gccgcccgct gagggcggct
     7681 gtcccggggg aggtgctggt cgcgccggga gccgggccgc cgagccccgc gccgcccgtg
     7741 cttccgccgg gacgggcggc acgcgtccgg ggcggcggag taacctcctc ttatgaccga
     7801 ctccgcgcac ctgttcctcg ttcccgagtc cgccgaggcc cacgtcgggg cccggctcgc
     7861 cgaggtgggg gagctggagt actcgcagtc gtcggcggtg ctcggctggc tggacgcgca
     7921 cggcgtccgc gcggacagcg accggctgcg cctgctgccg cccgaggcgc ggggcagcgt
     7981 ccccgccggt gccgaggcgc tgcccgtgcc gctgtccgag gaggagctgg accgcctgcg
     8041 caccgcgtgc gcggcgccgg acgtggcgga gctggaacgg gagctgcgcg cctaccgcga
     8101 gaccaccgag gaccgtgagc gcctggtcac ccgcgccctg gctggaggcg tcccaccgca
     8161 ccgcatcgcc gaactcaccg gcctggaccc ggccgacatc gcccacgccg cgagctagcc
     8221 gcacgcgccc cggcgcccgc ggcccggccg ggcgtgcggc gctcaggacc cgcaggcggc
     8281 cggggtgcgg ggtgtgcgga atgcgccccc ggagtaccgg gcagttggga tgactggcgg
     8341 ttagctgcgt aaggggctgt tcgggtgtag tcggtgcgcg gccccgtctc cccggggcgg
     8401 gcgaaacgtt gttgcggacg tggagccgcg tgagttgtgg gagaggaaca cggtgctggc
     8461 cgaggcgttc tgcaccagcg acgaccgggt gcgcgaggcg cagaccgtgc tggacgaggc
     8521 gcaggccgaa cgcacccgaa tgctggccgc gttcgcggtg accgtcggca atgacggagc
     8581 cgtggccgac ctgatggggc tgcacgagcg cgaggtgcgc gtcgcgcgcc gtacggtggg
     8641 caaggaggac gcccgcacca tggcctccgg cctgctcacc ccgtcgcccg gccccgaccc
     8701 cgattccgcg cccggaaccg aggagcaggc ggcaccggaa ccggtgcccg gcggcgtcac
     8761 gctgaacgac ctgctgcagc agccgcacgc ggacgtgcac gtgccgcgcc cgcgcgtcga
     8821 ggccaccgag ccgacgggcc ccgagcccca gccggtcgcc ccccacccgg tcgcgcacaa
     8881 cccgtacgcg acgccagcag cccccgccca gccgtacgcg gcgcagcagc acgcggccca
     8941 ggcgtacacc actcaggccc acgcggcgca cccgtctgcg gcccacccgc acgctgccca
     9001 cccgcacgct gcccacccgc tcactcacca gccgttcacc gcaccggaac ggccggaacc
     9061 gacggaaccg ccgggaacac ggtcccctgg cccctccgcg ccccggtccg aggcggcccg
     9121 tgaggcggag gcgtggtcgt cctccatgga ctcggtgctg gtgtggagct ggcagtccgg
     9181 agtggacctc cagttcgtcg cggaagaact gggtctggac ctgcgcgcgc tcctcgtccg
     9241 ggtccagacg ctcgcggccg agggccgcct gtcgctgcac gccccgccgc cgcccgcctc
     9301 gtccgacacc gcgggccgcc accggcgccg gcagggcagc ggccagcccg aggagtaccc
     9361 ctacgtcacc acgccgacgg acgtcctggg tccgttcacc acgcccgcct accgctgacg
     9421 cacgcgctcc cacggcctcg cgacgcgcac cccacgccgg tgcgcggtgc gcggtgcgcg
     9481 gtgcgcggtg cgcaccacgc cgacggccag cgcgcgcccg tcccgcgccc cgggcagact
     9541 gagcgcgggt gcacggcgct ggtcggagtt cggcgtgcgc gggcgcgtga aatgcgcggt
     9601 cctcaggcgc caacgcgccc atgtgctccg gtgcgaccag acgcgtcggc ccggggcctt
     9661 gccggggcgc gtggcggggg tttccgtggg taataccgca cccgcggcca gggggctgac
     9721 cgggtaccac cccgcgcagc acggcagggg ttggttccac gatcgtcgag ggagtgacct
     9781 ggaaagtgcc cgaacgcaga ggtcctgtgc cgccgtccag tcaggccccc gaaaacgtac
     9841 ccaccctggc cgccgccggg ccgccgccgc accagaggta cagcagcggg caggccccgc
     9901 actccgtacc cgagcccacg ccggccttcg ccgtgcccgc cggagccctg cgccgggccg
     9961 aagccgacga gggcgtttcc gggcgggcgg gtaacccgcg atgaccgccc tgcccgaggg
    10021 tgccgccccc cttgacctgc cccacatacg cactcgcgtc gataccgtcc tggccgactt
    10081 cctgcgagcc aagacgcgga gcgcggcggc ccgggcgtgg ccggaggaga tcaccaccac
    10141 cctgcacggc ttcctctcag ccgggggtaa acgcctgcgc cccaccttgt gcgtggtggg
    10201 ctggcacgcg ggcggtggcg gcagccccgc cccggcctcg gtcctgcggg tcgcggcggc
    10261 gttggagatg ttccacgcct tcgccctcat ccacgacgac atcatggacc actccctcac
    10321 ccgccgaggc cagcccaccg cccaccgcgc cctggccgcc ttccaccaag ggcgcggcga
    10381 cgccgatcag ctgggcgtcc acagtgcgat ccttctcggc gatctcgccc tggtgtggtc
    10441 cgacgaactc ctccacgccg cggacctcac ccccacccaa ctcgccgcca ccctcgacat
    10501 cgtcgatctc atgcggaccg agttggtcta cggccagtac ctcgacctct gcgccaccgg
    10561 acaccccacc gacgacgtcg aacgctgccg aaagatcgtc cgctacaaaa ccgtccgcta
    10621 caccctccgc caccccctgg ccatcggtgc caccctcgcc gacgcggaac cggccgtgca
    10681 cgccgccctg gacgcctacg cccaccccgt cggtgaggcg ttccagctgg ccgacgatct
    10741 gctcggcgtc tacggccacc ccgacgagac gggcaaatcc cgtctggacg acctgcgcga
    10801 cggcaagcac acgctgctca ccgccctcgc cctccgccac gcctccccgg ctgagcggca
    10861 caccctgcgc accctcctcg gcgcccccgg cctcaccgac gccgacgccg accgcgtgcg
    10921 cgccatcctg gacgccaccg gtgcccccac ccgcgtcgcc gaccgcatcc gggcctgccg
    10981 caggcaagcc gaacacctcc ttgaccaggc gcccttcccg cccccggcca ccacgacgct
    11041 gcggcacatc gcccacctgt gcaccgtgcg gaccgcatga agacccaaga gcgccgaacg
    11101 cggtgggagg agacctccca ggccctggct gagcaagcag cgaggagggg cattcacgca
    11161 tctccatgac aacgctccag agccctcgct gctcaccggc cgcgttcccg gggttccctt
    11221 atcccggggg cctggcaatg ggggccgtgg gcggcatgag cgtcagctcg gacagcatcg
    11281 atgaccgcgc accaccggcc cagcgaggta tccgccatgg caccagcacc ccagcacgac
    11341 gacgccacgc ccgccgaacc ttcccccttg cacctgcacg ttccccccgt ctactgcccc
    11401 atccctacca cccgtcaccc ccgcacagac gagttccgcg acaacggggc caactggatg
    11461 gcggaccacg gtctttgccc cgacgaccag cagcgtgacc gggtcatcgg cacccgctcc
    11521 gcggagtggg tcggcgacgc ggtcccggac ggcatccccg accgcatgca gatctgggcc
    11581 gactggttct acctgatgtt cgccgtggac gacttccacg acgaataccc caactggcac
    11641 caggccatcg acttctcggc ccgcctcgcc tgcaccatcg ccaaccccga cgcccaggcg
    11701 ttcccggcgg acaacccctt cgccgccccg ctgcgcgacg tggcacggcg ctaccacgaa
    11761 cacgccaccc ccacccagct caaccggtgg acccagcacc accgcgcctg gctgctcgcc
    11821 gtctgccgtc aagtcgctct cggccacgcc gggatcgtcc tggacctcaa cgactttgtc
    11881 accatgcgcc tgcacacctg cgccggtgaa gccacctacg cccccatgga gatggtggtg
    11941 gacgccgagg tccctgaagc tgagatgagt tcgcccgccg tccgcgccct ccgcgagatg
    12001 gccgtcttcg tcgcggcctg ggacaacgat ctcggctcct acggcaagga atggtggctt
    12061 tcccagcaga acagtgttcg ccccgacccg gttcctggca acatcgtcga tatcctgctg
    12121 cgcggcaccg gctgcacact ggaacaagcc ctcacgcgct ccatcgccat gcgcgaccgc
    12181 gcgatggtgc gcttcctgcg cccgcgtgaa caggtcctgc cccaggccag cgaagaactg
    12241 gccctgttcc tgaactacct gggcaccggc atcagcggca acatcaccgc agccttcacc
    12301 tccgagcgct acaccctgcc cgaccccgca cacccggacg ccctgaaggt cacgtactcc
    12361 gtccgcaccg aagccccgcc cgacgccgac cagcccctgc cgctgcccgc caccgcctgg
    12421 tggtgggacg acctctagac ccggggcacg ggttcgcacg tcccaggcgg cccggaccgc
    12481 gtgtagcgcg gcggctgagc ggacgccagg acggcgaagg tgccccgcct cggcccgtgg
    12541 ccggagcggg acacctcgtg tgcggggcca accagccgcg ccaggacgcc cggagggttc
    12601 cgggctcccg gcgcgtgcgg ggtggcgcgg gtgtcagtcc ggccaggtgc cggtgaggcg
    12661 gtggacggcg gtggcgccgc cacggttcac cgtggccttg acggcggcga agatcgcgcc
    12721 ctggagcgcc gcggccagca ggatttccgg ccagccgcgg tgggggtcgg tggcgtcggg
    12781 ggcgtcgtcg gcatggccca ggcgtttcca cacctgctgg aacaccgcgc ccgctaccgc
    12841 accgctggcg atacccgcga ggagaccgaa gggcttgtac gcgagcttgg ccgcgttcat
    12901 cggcggccct tccggcgccg ggtcaggaga acgaacgcga gggcggcggc caggccgccg
    12961 acgagcaggc cgcgatggtc gcgggcggcg gtgcccgcca gggcggcctt ctcctgaacc
    13021 gaagcagggg tgttggcctg ggccttggcg gtcagcgtcc gggtggtgcc ggtgagctgg
    13081 tccgtggcct gggcggcctt ggcccgcacc ggctctggcg ccttctcgcg caccgtctgc
    13141 gccagctgcg ccgccttggc cttcgcctgc cctgccttga ccttcgcctg cccggtgagc
    13201 tccgtcgcct tctgccgggc ctgcgccttg acgtcggcct tcccggccag cgcctcgatc
    13261 gtcacaccca gttcctcgcg ggtgtgctcg gcctgcgcgc gcagttcctc cggcgtgacc
    13321 tcgctgctgg gggcgggttc cgtcatcgct gtgcactctc cttgatgtgg gcgacatcgg
    13381 tcttcacgtt gtcgatggcc tcctgcggcg cgggcgcccc ggcctgggcg acttccttct
    13441 tgcccgctgc cgcgaggacg gcggcgagcg cggacagcgc gaacgtcacc accagggccg
    13501 ccagccacgg cggccacacc agggccaggg cgatgatcac cgtcgctacc gctgcctgga
    13561 gcgcgaacac cgcgaccagg cccgccgcgc cgaacaggcc gccgccgaga ccgaaccgtt
    13621 tacccttctg cttcatctcc acctgcgcca ggcgcagttc cgtgcgcacc agctgcgtca
    13681 gctgctcgga cgcctgcttg acgagatcag ctgccgtggc ctcccgcagc ggacccggcg
    13741 gagtcttcgg tgagctgtcc atggcgcgcg catacccacc gccgcccacg acacacccgc
    13801 cggtccaggg ggcagtaccg cacatccgcc ccggccacca gagaggccgc cgcctcagcg
    13861 tacgtaccgc gctgtacccg ccgcggccgt ccgcagcgca catggccgac agcgcgttgc
    13921 cgccccacct tcgacggatc gcggcacgcc cccgccgaca gcgcccgcag cacgtcctgt
    13981 ccggtgggcg ggcgcggggc gcggggcgcg gtggcggggg cgcctgccaa ccgcgcggta
    14041 accgagcggc ggcgtggggg cgggggcacc atcgagatat ggccgtgctc gtcgggacgt
    14101 ccgggtggca gtaccgggac tggcgcgggg tgctctaccc gcccgggctg ccgcagcggc
    14161 tgtggctgga ggggtacgcg cgccgcttcc cgaccgtgga gagcaacaac gccttctacc
    14221 gcctgcccgc cccggagacg ttcgcggcct ggcgggagcg gaccccgccc gggttcgtca
    14281 tggcgctcaa ggccagccgc ttcctcaccc acatccggcg gctgcgcgaa cccgaggagc
    14341 cggtgcggcg gctgctggcg cacgccgggc cgctggcgga gcggcacggc ccggtgctgc
    14401 tccagctgcc gccgacgcta cccgaactct tgcccagtgc tccacccttt agggtggagg
    14461 tgcagggcat tcttgcgtcg gcggcccgga ggggcgcagc gccactgcta aggtcgcctt
    14521 gtccgacaac ggagttgtcg gacctaccgc cggacgggcg ggaggtaaag cctgtggaga
    14581 cctggtgagt ccgctcctca ccgagcggca cgggtccgtg aagcaggaac ccgcggtggc
    14641 accgcgtagc ggtgcggacc ggaatcgtag ccccttcagg gcaacgagga cgtcaaggcc
    14701 gccgcgccct gtccacgtgg gcggcccgca tcgccgacac ctggcccccg gacgccgacg
    14761 tctacgccta cttcaacaac gaccccggcg gcgcggccgt cctcgacgcc acgctgttca
    14821 cccggttcac ccgccccacg gccccggcgt ccccggaccg cccggcggaa ccggctcccc
    14881 ggccgccccc acgatgaggc ggggccgcag ccgtgtgacg ccccggccga cgcgggacgc
    14941 ccccgcccgc ccgggccacc ccagaaagca cgccattagg ctgaccccat ggctgacgcg
    15001 acatacaagc tgatcctcct ccgtcacggc gagagcgagt ggaacgcgaa gaacctgttc
    15061 accggctggg tggacgtcaa cctgaccgac aagggcgaga cggaggccgt gcgcggcggt
    15121 gagctgatgg ccgacgccgg tctgctcccc gacgtcgtcc acacctcggt gcagaagcgg
    15181 gccatccgca ccgcgaatct cgccctggag gcgtgcgacc gccactggat tcccgtccac
    15241 cgctcctggc gcctgaacga gcgccactac ggcgcgctcc agggcaagga caaggcccag
    15301 acgctcgccg agttcggcga ggagcagttc atgttgtggc gccgttccta cgacaccccg
    15361 cccccggtgc tggaggacgg cgccgagtgg agccaggccg acgacccgcg ctacgccatg
    15421 atcccgccgg agctgcgccc gcgcaccgag tgcctgaagg acgtcgtcca ccggatgatg
    15481 ccctactggt acgacagcgt cgtccccgac ctcagcaccg gccgtaccgt cctgctcgcc
    15541 gcccacggca acagcctgcg cgccctggtc aagcacctgg acggcgtctc cgacgcggac
    15601 atcgccgggc tcaacatccc caccggcatc ccgctcctct acgagctgga cgccgctttc
    15661 caccccacca accccggtgg cacctacctc gacccggaag ccgccaaggc agccatcgaa
    15721 gcggtgaaga accagggcaa gaagtagcaa agtagcccct ggtgtatgac gaggcccccg
    15781 tgcggagagc acgggggcct cgtcgtacgc gctgccgtca gtgggcggct agccgcagct
    15841 gccgccgcag ttgcaggggc cgccggactg gcagccgcag gagcagccgg ggccacaccc
    15901 gcacgacagc gacagcgaca acgccaacga cgacaacgac gacaacgacg acaacatggc
    15961 ctccgccctc cgcgggccta acgtgtgctt acggagtcgt gccaacaccg tttccctcct
    16021 cgggccggtt ccctcggtaa ctcccaggga agcgaggcca cagcggacgc ggcaacggcg
    16081 cgcggagggc gcgcggaagc aagcgcgcgc ggcgggcggc gctcgtcccg cgccccctgc
    16141 tgtgtcctgc cgcgtcagtc ggacgcgggc tcgtcggccg gggacgacgc cggggagtcc
    16201 ggggtcacag gggcctgcga agacgtcgcg gccgacgcgg cggccggggc ggtctcggtg
    16261 gcggccaccg cggcggccgg gtccagctcg tccgcgtagt cgccggtgac caggtacacc
    16321 acgcgccggg ccaccgagac cgcgtggtcg gcgaaccgct cgtagtagcg gcccagcagt
    16381 gtcacgtcca cggccgtctc gatgccgtgc ttccagcggt cgtccatcag gtgctggaac
    16441 agggtgcggt gcaggtcgtc catgcggtcg tcgtcgtgct ccagctggag cgccagctcg
    16501 acgtccttgg tgatcagcac ctcggccgcc ttggccatga gccgctgggc gagctggccc
    16561 atctccagga tcgtggcctg gaggtcgcgc gggacggcgg agtcggggaa gcgcagccgg
    16621 gccaccttgg ccacgtgctg ggccaggtcg ccggagcgct ccagatcggc gctcatgcgc
    16681 aggctggtca ccacgatgcg caggtcggtg gcgacgggct gctggcgcgc cagcagctgg
    16741 atggccttgc tctccaggct ccgctggagg tcgtccacct tgtcgtcgtt ggcgatcacg
    16801 ctctcggcga gcttcaggtc cgcgtcgagc atggccgtgg tggcacggcc gatcgcggaa
    16861 ccgacgagcc gggccatctc gaccaggctg tcgccgatcg catccagctc ctcgtggtac
    16921 gcgtcccgca tggcagtcct tccctcgctc ctgggctacg ccggacaggc cgggcgtcgg
    16981 ccgctgtcct acgcctccac gctggcgggg gaaggcgtcg ggcgcgaccc cgtcaagtga
    17041 atcacctacc acgttcggat gaactctggg cgacgtaaca gaacgcggtg gtcgcgggtg
    17101 gtgcggcacc ggcgccctga gcccgtgttt tccgttctgc aggggtatgc gccgcaccca
    17161 gtgaatcacc gccgacctgt cggtgaactc tgggggacga gtgcccgagc tgagcggcca
    17221 caccccgcga cccccgctcc ggcccgctta gtctgaggac atggacgtga acgcggcggt
    17281 tgccgcagtg gccgcgatcg ccggtgtgtg cacgggcgct atcgccgtcc tcgcgttccg
    17341 ctggagtgag cgcgagcagg cgcggccgac ccgctcctcg ctgcacaccg agcccgtgct
    17401 gccgcccggt gtggacaccg tgctgtccgt gctgcgctcg tcggccgtgg tcctggacga
    17461 ggcggacgcc gtcgtcaagg ccagctcggc cgcgtacgcg ctgggcctgg tgcgcggcgg
    17521 ccggctggcc gtggagccga tgctccagat ggcccgcgag acccggcggg acggcgagat
    17581 acggcaggtc gagctcgacc tcgcacggcg cggcagaggc gacgccctcg cggtgtccgc
    17641 ccgcgtcgcc ccgctcggct cccggctggt gctgctgctg gtggaggacc tcaccgaggc
    17701 ccgccgcatc gaggcgatcc gccgcgactt cgtagccaac gtcagccacg agctgaagac
    17761 gcccgtcggc gcgctgtccc tgctgtccga agccgtcctg gacgccagcg acgaccccga
    17821 ggccgtccgc cgcttcgccg gccgcatgga acacgaggcg acccgcctga ccagcctcgt
    17881 ccaggagctc atcgacctct cccgggtgca gaacgacaac ccgatggagg actccgagcc
    17941 cgtctccgtg gaggagctgg tcggcgaggc catcgaccgc tgccggcagg gcgcggacgc
    18001 caagcagatc accatggccg ccggcggcgt cgaggagctg cacgtcttcg gccaccgtgg
    18061 ccagctcgcc gccgcgctcg gcaacctggt ggagaacgcc gtcaactact ccccgccccg
    18121 cacccgcgtc ggcatcgccg cccgccgggt gcccgcgccg ggcggggaca tgatcgagct
    18181 cgccgtcacc gaccagggca tcggtatctc cgaacgcgac cgcgaccgga tcttcgagcg
    18241 gttctaccgc gtcgatcccg cccgctcccg cgccaccggc ggtaccggcc tcggcctggc
    18301 catcgtcaag cacgtggccg cctcgcacgg cggcgaggtc accgtgtgga gcgccgaggg
    18361 ccagggctcg accttcaccc tgcgccttcc cgaggcgggc agcgcccggg agaaggccga
    18421 ggaaagccgc cgcagccgca cccggctcag cggcgcactg cacaaacccg gcgagtacgt
    18481 gggccctgac gacggcgagg aagccgacat cgtggacccc gtcgaggccc gcccaagaga
    18541 accacacgca tccccggagg tccttccgtg acccgagtgc tcgtcgtcga ggacgaggag
    18601 tcgttcagcg acgctctgtc ctacatgctg cgcaaggagg gcttcgaggt cgccgtagcg
    18661 gccaccgggc ccgacgggct ggacgagttc gagcgcaacg gcgccgacct cgtgctgctg
    18721 gacctcatgc tgccggggct gcccggtacc gaggtctgcc gtcagctgcg cagccagagc
    18781 agcgtgcccg tcatcatggt gacggccaag gacagcgaga tcgacaaggt cgtcggcctg
    18841 gagataggcg ccgacgacta cgtcaccaag ccgttctcct cgcgcgagct ggtcgcccgc
    18901 atccgcgcgg tgctgcggcg ccggggcgag ccggaggaga cggtccccgc cgcgctggag
    18961 gccggtcccg tgcgcatgga cgtggaccgc cacgtggtca ccgtctccgg cggcaaggtg
    19021 gacctgccgc tcaaggagtt cgacctgctg gagatgctgc tgcgcaacgc cgggcgggtg
    19081 ctgacgcgga tgcagctgat cgaccgggtg tggggcgcgg actacgtggg cgacaccaag
    19141 acgctcgacg tgcacgtcaa gcggctgcgc gcgaagatcg agccggaccc gggcgcgccc
    19201 cgctacctgg tcacggtccg cggcctgggc tacaagttcg agccctgaca gacggggcgt
    19261 cacgaaaacc gccggacggg ctcacgcgag ggtgagcccg tccggcggtg tggtgcgcga
    19321 agggtgacgg aaccggaatc agcgcgctgc ggactattcc gcctcacctg gcgtctgggc
    19381 cgtctccggc gcctcggtgc cagccggggt ttccgcgcca gccggtgcct cagcgtcgtc
    19441 cggggcctgc tcctcgcccg gggcctcctc gcccggggtc tgcccgtcgt ccggcgactg
    19501 ggcgccctcc ggcgaacccg tgggctcctg cgacgggccc cactcggagt aggtcagctg
    19561 cgaggcgggg acgaccagcg cggggacctc gatggcgccc gtctcgctca gctcgaacgt
    19621 cagcggctgc gccgcgccgt cggtgatgcc ctgggcggcg gcgtcctcga tgacggcggc
    19681 cgcgttgccc tcgccgccga gcatcaggtg gccgccggcc ggaaccgtca gttcgccgcc
    19741 ctccgccggg gagagctgtg cctcgccgga gccgtcatcg gaggcgaagg tgatcgcctc
    19801 cagggtctcg tcctcggtgc cctcgttgaa gatccgggcg gtgatggcgg cgggaccctc
    19861 gccgtcctcc gtggtcacca cggagatgtt ctggatctcg atatcgccct gcgtcacgta
    19921 cgcgtggtcg gggcggatct cgttggtcgc tgcgttgact cccgcgccgc acccgaccag
    19981 cgcggaggac gagagcgcga ggacggcggc gacggcgccg cgtcgaaggc tgctgcggct
    20041 gctgctcacg gcggcgcatc tcctagcagt gatgaaggct tgtctgtcag cggcagcgta
    20101 ccgaccctgg gcgccgtgtc cgcacccgcc ccgcccctgt ccacgcggcc cgggctccgc
    20161 gcggggtcgc gtccgcgccg cgcctggctc cccgccgagc ctccgtcagg tctccggcga
    20221 gtcgccccgg gtccgcgcgc gtcggggtcc gggggcggcg ggggcgcgtc tccgagacgc
    20281 gtcggcattc gggccgggag gaatgcccgc gcccctcgga aatcgatctt cagaccgttc
    20341 gcggtcgcgt tgccggaagc atcgcggagt tgtcgtgatc ggtgtgaagg gctggaacac
    20401 gcacggtgac aaggggggcg aatcggtcac gcctcgggtc cttcgcgcgg gtaacggcgg
    20461 cgtttccttt cctggtcaga ggtgccccca cctgcgaata cccgcttgca tgagggtgcc
    20521 gcagcacgat aagggcgctg ttgtcaagcc ccgagatgtg ctctgacctg cgaaaacgcc
    20581 attcggtgcg gccctctctc gtgctatcct ggatagccac ggaaggggta cctgtcacat
    20641 gacgttcaag gttggcgaca ccgtggtcta tccccatcac ggggccgcgc tgatcgaggc
    20701 catcgagact cgtcagatca aaggcgtgga caagacctac ttggttctga aggtcgccca
    20761 aggcgacctc gaagttcgtg tgccggcgga aaacgccgaa ctggtcggcg tacgggatgt
    20821 ggtggggcag gacggcctgg agcgcgtctt cgatgtgctg cgcgcgccgt atgccgagga
    20881 gcccaccaac tggtcccgcc gctacaaggc gaacctggag aagcttgcct ccggtgacgt
    20941 catcaaggtg gccgaggtcg tccgcgacct gtggcgccgg gagcgtgagc gcggcctctc
    21001 cgcaggggag aagcgcatgc tcgccaaggc gcggcagatc ctcgtcagcg aactcgcact
    21061 ggccgagaac accaacgagg acaaggccga ggccctgctc gacgaggtgc tggcttcctg
    21121 agccgggctg gtttcccgca ccgggagcca ccaggggtct gcgagcggtc atgagaccac
    21181 cggtgatggc gccaccgcct cgcaccgccg tcgcgtgaga tgccgcggcg ctcgaacggc
    21241 ggccctacgg ccgtccgtta ccgggcgctg cggcatttcc gtcgccggac gtggcgatcg
    21301 gggagaccga cgcccggacg acagccccct gcgcacccat cgccgacgag cggcgtaccg
    21361 tcgtgcggcg aagaatgccg ggcccgggca gccgacgcga tcggttgtca cggaagggac
    21421 cgatcagggt ctcgtacccg gcacgttctg gccataccca tcccggatga ggacacaaac
    21481 ctgaacgtgc aaccaaggtc cgatgagcag cccgccgacg cggccgggat gacgacggca
    21541 gccctcccgc gcaccgctcc gtcgcgcacc gctccgcccg ccgcgcggac cgccgccgtc
    21601 atcccggccg ccggacgcgg cgtgcggctt ggccccggag cgcccaaggc gctgcgcgcg
    21661 ctcggcggta cgcccctcct cgtgcacgcc gtgcgggcgg tggcccgtgc ccgcgaggtc
    21721 ggcctcgtcg tcgtcgtcgc gccgccacag gccgccgccg aggtgcgcca cctcctcgac
    21781 gcccatccgc tgcccgccgc gcccgccgcc cagggcgcgg atgtcgtcgt cgtccccggc
    21841 ggggccaccc ggcaggagtc cgtgcgccgt ggcttggacg ccctgcccgg ggaggtggag
    21901 atcgtcctcg tgcacgacgc ggcccgcccg ctggtgcccg ccgacaccgt ggacgccgta
    21961 gccgccgccg tgcgcgccgg tgcgcccgcc gtcgtccccg cgctgccgct gacggacacc
    22021 gtcaaggagg tcgagccgca ggctgccggt gcgcccgagc cggtcatcag cacgcccgcc
    22081 cgggcccggc tgcgcgcggt ccagacgccg cagggtttcc agcgcgcggt gctcgccgag
    22141 gcgcacgcgg ccttcgccgg cgcgggggag ggcgccacgg acgacgccgg gatggtcgag
    22201 cggctcggcc agccggtcgt cgtcgtcccc gggcacgagg aggcgttcaa ggtgacccgg
    22261 ccgctggacc tcgtgctggc cgaggccgtg ctcacccggc ggagggccga tggctactga
    22321 gcccccgggc ggcgtcgccg tgccgctggt cggcatcggc accgacgtgc acgccttcga
    22381 agccggacgc ccgctgtggt gcgcgggact gcggtgggag gacggcgacg ggctcgcc
//
