LOCUS       NZ_JAEVFI010000008     24476 bp    DNA     linear   CON 14-SEP-2024
DEFINITION  Streptomyces sp. JJ66 scaffold8_size197547, whole genome shotgun
            sequence.
ACCESSION   NZ_JAEVFI010000008
VERSION     NZ_JAEVFI010000008.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces sp. JJ66
  ORGANISM  Streptomyces sp. JJ66
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 197547)
  AUTHORS   Jose,P.A. and Jha,B.
  TITLE     Draft genome of Streptomyces sp. JJ66
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 197547)
  AUTHORS   Jose,P.A. and Jha,B.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-JAN-2021) Marine Biotechnology and Ecology Division,
            CSIR - Central Salt and Marine Chemicals Research Institute, G.B.
            Marg, Bhavnagar, Gujarat 364002, India
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 25-MAY-2017
            Assembly Method                   :: Velvet v. V 1.2.10
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 320.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_019303495.1-RS_2024_09_14
            Annotation Date                   :: 09/14/2024 03:51:48
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,515
            CDSs (total)                      :: 4,446
            Genes (coding)                    :: 4,340
            CDSs (with protein)               :: 4,340
            Genes (RNA)                       :: 69
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 61
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 31 of 106
            Pseudo Genes (incomplete)         :: 82 of 106
            Pseudo Genes (internal stop)      :: 3 of 106
            Pseudo Genes (multiple problems)  :: 9 of 106
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 09:22:12
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 17639
            Orig. end                         :: 42115
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JAEVFI010000008.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..24476
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="1"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..24476
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..24476
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:14476](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..14476
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            90..569
                     /locus_tag="JJV70_RS07585"
                     /old_locus_tag="JJV70_07595"
     CDS             90..569
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018558121.1"
                     /locus_tag="JJV70_RS07585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJV70_07595"
                     /product="ATP-binding protein"
                     /protein_id="WP_219047123.1"
                     /transl_table=11
                     /translation="MESSGRALQPPPAGAVAYEGTWRFTAPALDSSVPRVRHAVRDLVR
                     RQGAPVSTEVMDGLLLIVSELVTNSVRHAALLSPELGVEMSIGSGWVRVAVEDGHPYRP
                     KALAADPALEHVGGRGLLLVKAVCAEFAGTCDVEQTAAGGKVIWACLPLWAPAPA"
     gene            complement(701..1246)
                     /gene="idi"
                     /locus_tag="JJV70_RS07590"
                     /old_locus_tag="JJV70_07600"
     CDS             complement(701..1246)
                     /EC_number="5.3.3.2"
                     /GO_function="GO:0004452 - isopentenyl-diphosphate
                     delta-isomerase activity [Evidence IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="idi"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019432687.1"
                     /locus_tag="JJV70_RS07590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJV70_07600"
                     /product="isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="WP_257573575.1"
                     /transl_table=11
                     /translation="MTTPIMLELVDEDGVTTGTAEKLSAHQPPGHLHRAFSVFLFDDTG
                     RLLLQRRALGKYHSPGVWSNTCCGHPYPGEPPFVAAARRVGEELGVAPVLLAEAGTVTY
                     RHPDPASGLVESEYNHLFAGLVRAEPRPDPAEIAETAFVTPDELAARHARDPFSAWFLT
                     VLDAARDGIRAVAPEAGW"
     gene            complement(1330..2265)
                     /locus_tag="JJV70_RS07595"
                     /old_locus_tag="JJV70_07605"
     CDS             complement(1330..2265)
                     /GO_function="GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006133326.1"
                     /locus_tag="JJV70_RS07595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJV70_07605"
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="WP_219047125.1"
                     /transl_table=11
                     /translation="MGAGHHHTGPSPGTSGTASAAYRGRLLIALVIAVTLLVVQLVGAW
                     LTGSLALLADAGHVATDATGIAVALAAIGFAARPASERRTFGFARAEILAALLNCVLLL
                     GVGGYIVVEAVKRFQEPAEVPGVPTVIVGVIGLALNCLSLLLLMRGQKESLNVRGAFLE
                     VLADTLGSLAVVASALVIIVTGWTRADVVASLIIALMIVPRTVKLAREALDVLLEAAPK
                     DVDVAEVRRHILDVTGVESLHDLHVWTITSGMPVLSVHVVVEDKLLEAGEHDRVLHDLQ
                     ACLGAHFDVAHCTFQLEPRGHWAHEAQVCH"
     misc_feature    2305..2321
                     /note="TFBS match to RicR, Copper-responsive regulator,
                     confidence: weak, score: 21.06"
                     /tool="antismash"
     misc_feature    2334..2349
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 15.6"
                     /tool="antismash"
     misc_feature    2336..2350
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.72"
                     /tool="antismash"
     misc_feature    complement(2390..2406)
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 20.07"
                     /tool="antismash"
     gene            2715..4532
                     /locus_tag="JJV70_RS07600"
                     /old_locus_tag="JJV70_07610"
     CDS             2715..4532
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018568721.1"
                     /locus_tag="JJV70_RS07600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJV70_07610"
                     /product="DUF5941 domain-containing protein"
                     /protein_id="WP_219047126.1"
                     /transl_table=11
                     /translation="MPTAILTGPPAAGSTLEGDLRSLGFTVRTAAAPSGVAALLAAVPA
                     AERAAVVDHRFTGHPHSLRLALTDPRFPAAAIPGAVTAQPQARGALARAVAADPDPQAV
                     PAALETAGVPVHRPDLGVLVAAVPADAEALAAARAATAAVDDERVRLRSAVKSRDGFFT
                     TFFISPYSRYVARWCARRGLTPNHVTTASLLVALLAAACAASGTRAGFAAGGVLLIASF
                     LLDCADGQLARYALRYSTLGAWLDATFDRAKEYAFLAGLALGAARGGDDVWALALGAMV
                     IQTVRHVVDFSFTEGNHYETSAGPQGADTGGAGHASPTAALSGRLDRVGWTVWARRMIV
                     LPIGERWALIAVLTALTTPRTTLVVLIAGSVLAACYTTAGRVLRSVTRQAPRTVGAARA
                     LADLCDAGPLAELAARTAPPARRLAPVFAALGAVAVAGAALWAPAGSWIPVAAAALYVL
                     LSGWAVARPLAGPLDWLVPPLFRAAEYGTVLALAASSQANAAPGVNTALPVAFCLVAAV
                     AYHHYDTVYRIRGGAGAPPRLLVRAVGGQEGRTLLVTVAAALWSGGTGFPLALSVLAGT
                     VALVVLAESIRFWVSAAAPAVHDETGVPA"
     gene            4529..5263
                     /locus_tag="JJV70_RS07605"
                     /old_locus_tag="JJV70_07615"
     CDS             4529..5263
                     /GO_function="GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064: glucose-1-phosphate
                     adenylyl/thymidylyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018955403.1"
                     /locus_tag="JJV70_RS07605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJV70_07615"
                     /product="sugar phosphate nucleotidyltransferase"
                     /protein_id="WP_219046991.1"
                     /sec_met_domain="NTP_transf_3 (E-value: 5e-13, bitscore:
                     43.1, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIGLVLAAGAGRRLRPYTDTLPKALVPVDGETTVLDLTLGNFAEV
                     GLTEVAIVVGYRKEAVYARKEELESRYGLKLTLIDNDKAEEWNNAYSLWCARDVIKQGV
                     ILANGDTVHPVSVEKTLLAARGKGQIVLALDTVKQLADEEMKVVTDDSGGVRKITKLMD
                     PAEATGEYIGVTLIEGEAAEALADALRTTFERDPDLYYEDGYQELVSRGVTIDVEPIGD
                     VRWVEIDNHDDLAKGREIACQY"
     gene            5251..6312
                     /locus_tag="JJV70_RS07610"
                     /old_locus_tag="JJV70_07620"
     CDS             5251..6312
                     /GO_function="GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fe-ADH"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DHQ_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1181: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008413836.1"
                     /locus_tag="JJV70_RS07610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJV70_07620"
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="WP_219046992.1"
                     /sec_met_domain="Fe-ADH (E-value: 2.5e-22, bitscore: 72.6,
                     seeds: 218, tool: rule-based-clusters)"
                     /sec_met_domain="DHQ_synthase (E-value: 7.2e-08, bitscore:
                     25.3, seeds: 76, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPVLTRLIPSPVVVDIRRGALEDLASVLADERISASGTLAVAISG
                     GSGAALRERLAPALPGASWYEVGGGTLDDAVKLADAMKSGRYDAVVGLGGGKIIDCAKF
                     AAARIGLPLVAVATNLSHDGLCSPVATLDNDAGRGSYGVPNPIAVVIDLDVVRQAPSRF
                     VRSGIGDVISNISAVADWELSHRATGEKIDGLAAAMARQAGEAVLRHPGDIGDDGFLTV
                     LAEGLVLTGISMSVAGDSRPASGACHEINHAFDLLYPKRAASHGEQCGLGAAFAMHLRG
                     AHQECGLMVEVLRRHGQPVLPQDIGFGVEEFVTAVEYAPQTRPGRYTILEHLDLSTDQI
                     RDAYADYAKAIGS"
     gene            6290..7069
                     /locus_tag="JJV70_RS07615"
                     /old_locus_tag="JJV70_07625"
     CDS             6290..7069
                     /EC_number="2.7.8.-"
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_function="GO:0000287 - magnesium ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA]"
                     /GO_process="GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008413838.1"
                     /locus_tag="JJV70_RS07615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJV70_07625"
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="WP_219046993.1"
                     /transl_table=11
                     /translation="MPKPSVAELRPVVHPEGVKDRRSGEHWAGRLYMREISLRVDRHLV
                     GTRVTPNQLTYVMTLAGVLAAPALLVPGIWGAVLGVVMVQLYLLLDCVDGEIARWKRQF
                     SLGGVYLDRVGAYLCDAAVLVGFGLRAADPWGTGGVEWLWAFLGTLAALGAVLIKAETD
                     LVAVARHQGGLPPVQEAASEPRSSGLALARRAAAALKFHRLVLGIEASLLILLLAIVDA
                     ARGDLFYTRLGVAVLAAIALLQTLLHLVSVLASSRLR"
     misc_feature    complement(7113..7130)
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 18.77"
                     /tool="antismash"
     gene            7123..7977
                     /locus_tag="JJV70_RS07620"
                     /old_locus_tag="JJV70_07630"
     CDS             7123..7977
                     /EC_number="2.4.-.-"
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011031159.1"
                     /locus_tag="JJV70_RS07620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJV70_07630"
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="WP_219047127.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 6.7e-10,
                     bitscore: 32.6, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGDRPAELRALLESVTRQDGDPVQVAVVGNGAPLPELPDLPGGLR
                     TRELPENLGIPGGRNAGVELFGTGGREVDVILFLDDDGLLPRADTAELLRQAFADDSQL
                     GIVSFRIADPASGETQRRHVPRLRAAAPMRSSRVTTFLGGASAVRTAVLQQVGGLPDDF
                     FYAHEETDLAWRALDAGWEIDYRADLVLHHPKTLPSRHAVYHRMVARNRVWLARRRLPL
                     PLVPVYLGVWVLLTLLRRPSRAALRAWLGGFREGWATPCGPRRPMRWRTVWRMTRLGRP
                     PVI"
     misc_feature    8058..8071
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 17.36"
                     /tool="antismash"
     gene            8074..8985
                     /locus_tag="JJV70_RS07625"
                     /old_locus_tag="JJV70_07635"
     CDS             8074..8985
                     /GO_component="GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018838708.1"
                     /locus_tag="JJV70_RS07625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJV70_07635"
                     /product="ABC transporter permease"
                     /protein_id="WP_219047128.1"
                     /transl_table=11
                     /translation="MHAPPHPDDALTPAQLADKYGLSVSGARPSLPEYVRQLWHRRHFI
                     GAFSRAKLQAQYSQAKLGQLWQVATPLLNAAVYFLIFGLILNGREGVPGGDGNYVPFLV
                     IGVFVFTFSQQSVLSGVRAISSNQGLVRALHFPRASLPLAFVLQQLQQLLYSMVVMLVV
                     LLAFGQRPGLSWLLVIPVLGLQFVFNGGLAMIFARLGSSTPDLAQLMPFVLRTWMYASG
                     VMFPLHHMLVTNAKLPVWAADLIAANPAAVFMDLMRFALIDDYTYADLTPFPWLLALGW
                     ALLAGVFGFVYFWKAEERYGRG"
     gene            8972..9790
                     /locus_tag="JJV70_RS07630"
                     /old_locus_tag="JJV70_07640"
     CDS             8972..9790
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016907919.1"
                     /locus_tag="JJV70_RS07630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJV70_07640"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_219046994.1"
                     /transl_table=11
                     /translation="MAVADPTTPTNLAKAPQAPDRRPTVIADDVHIVYRVYGGARGKGS
                     ATAALNRIMRRKPGGGRVREVHAVKGVSFTAYRGEAIGLIGSNGSGKSTLLRAIAGLLP
                     PERGKVYTDGQPSLLGVNAALLNDLTGERNVVLGGLAMGMSREEIRARYQDIVDFSGIN
                     EKGDFITLPMRTYSSGMSARLRFSIAAAKDHDVLMIDEALATGDKKFQKRSENRIRELR
                     REAGTVFLVSHNNKSIRDTCDRVLWLEKGELRMDGPTEVVMKAYEEFTSK"
     misc_feature    complement(9941..9955)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.61"
                     /tool="antismash"
     gene            10001..10930
                     /gene="hpnC"
                     /locus_tag="JJV70_RS07635"
                     /old_locus_tag="JJV70_07645"
     CDS             10001..10930
                     /EC_number="2.5.1.21"
                     /GO_function="GO:0004311 - farnesyltranstransferase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003962491.1"
                     /locus_tag="JJV70_RS07635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJV70_07645"
                     /product="squalene synthase HpnC"
                     /protein_id="WP_219047129.1"
                     /sec_met_domain="phytoene_synt (E-value: 4.6e-35, bitscore:
                     114.6, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 1.7e-42,
                     bitscore: 139.1, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAWTPTAQAPVRGVLDQAAAENFPVAPAFLPAAGRAALLAVYGY
                     ARLVDDIGDGDLAPGGADARLFGVPPEHAEDRPALLDAAEADVHRLLDAARWPGAPGPR
                     HPLVRALLPAVRAHALTAEPFLALIEAGRLDQHRHTYTTWEELLGYCALSAHPVGRLVL
                     AVTGTASPERVRRSDAVCTALQVVEHLQDVAEDRARGRVYLPAEDLARFGVREADLDAP
                     VTCAALRSVVACLAERSFALLDEGTGLVASVPGRLRLLLAGYAGGGRAALRALAAARYD
                     VLAGPPTAARPAVLRETAAVLMAARRVR"
     gene            10942..11949
                     /gene="hpnD"
                     /locus_tag="JJV70_RS07640"
                     /old_locus_tag="JJV70_07650"
     CDS             10942..11949
                     /EC_number="2.5.1.103"
                     /GO_function="GO:0016767 - geranylgeranyl-diphosphate
                     geranylgeranyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0016117 - carotenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnD"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018848334.1"
                     /locus_tag="JJV70_RS07640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJV70_07650"
                     /product="presqualene diphosphate synthase HpnD"
                     /protein_id="WP_219046995.1"
                     /sec_met_domain="phytoene_synt (E-value: 4e-59, bitscore:
                     193.5, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 1.3e-70,
                     bitscore: 231.5, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTPATSAPTTPDPTGESSAPGGAGPGPQEPPAPVLAAYGYCETVT
                     AQQARNFAYGIRLLPPPKRRALSALYALSRRVDDIGDGFLDADTKTARLADARTLLARV
                     RDGAVAADDTDPVALALTDAAHRYPVPLDAFDELIDGVLMDVTARTYRTWDDLRDYCRC
                     VAGAVGRLTLGVFGTAPGAPDAARAPEYANTLGLAMQLTNILRDLREDARSGRSYLPYE
                     ELAAFGCVGAFDAATAPPGADLTGLVHHQARRARRLFAEGYRLLPQLDRRSAACVAAMA
                     GIYRRLLDRIEADPAAVLRGRVSVPPRQKALTAVRGLTGLDAALVRRAIRRSAR"
     gene            11946..13406
                     /gene="hpnE"
                     /locus_tag="JJV70_RS07645"
                     /old_locus_tag="JJV70_07655"
     CDS             11946..13406
                     /EC_number="1.17.8.1"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016470909.1"
                     /locus_tag="JJV70_RS07645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJV70_07655"
                     /product="hydroxysqualene dehydroxylase HpnE"
                     /protein_id="WP_219046996.1"
                     /sec_met_domain="DAO (E-value: 6.1e-11, bitscore: 35.9,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDTLAPEGGQAPARGSAVVVGGGLAGITAALRLADAGVTTTLLE
                     ARPRLGGLAFSFRRETPAGVLTVDNGQHVHLRCCTAYRWFLDRVGARALAPLQRRLDIP
                     VLDARTRRVGRIRRTAAPVPLHLATALARYPHLTPADRLRAARAALALRRLDPADPALD
                     GQDFGTWLRRQGQSPRGIEALWDLVGVATLNARARDVSLALAAMVFRTGLLSDAGAADL
                     GWARVPLGTPHDTLARRALTSAGVTVRTGVRVRGLGQHPGGRWHLDTGRAPGVSPESAD
                     AVVLAVPQDRAAALLPTGALPDAGRLARIGTAPIVGVHVLYDRPVLRRPFFAALGSPVQ
                     WVFDRTPACGLAPDSGQYLALSQSAAHADIDAPVRVLRERYLPALARLLPAARTARVRA
                     FFVTRERHATFAPGPGVERLRPAAHTNAPGMYLAGAWCATGWPATMEGAVRSGHAAARA
                     ALARLGHPPGDTPWESPSGRPLNAKETL"
     gene            13403..14476
                     /locus_tag="JJV70_RS07650"
                     /old_locus_tag="JJV70_07660"
     CDS             13403..14476
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015656372.1"
                     /locus_tag="JJV70_RS07650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJV70_07660"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_219046997.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 5e-58, bitscore:
                     189.9, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNPVQPAPAGIDSAAVTALLTRGRTLPQPLLRAAVARLAPPMDTV
                     AAYHFGWIDAEGRPADGDGGKAVRPALALLSAEAAGAGPKTGIPGAVAVELVHNFSLLH
                     DDLMDGDEQRRHRDTVWKVHGPAQAVLAGDALFALAGEILLELGTADAARATRRLTRAT
                     RALIDGQAQDISYEHRERVTVEECLEMEGNKTGALLACSASIGAVLAGADDPTADALGA
                     YGHHLGLAFQAVDDLLGIWGDPQATGKQTWSDLRKRKKSLPVVAALGGGGAAARQLGEL
                     LTADAKKPQAEVDDFDEAQFATRAALIEEAGGRDWTAAESRRQHGAAVRAVSTVAMPSA
                     VRAQFLALADFVVDRQR"
     gene            complement(14554..15360)
                     /locus_tag="JJV70_RS07655"
                     /old_locus_tag="JJV70_07665"
     CDS             complement(14554..15360)
                     /EC_number="3.1.3.48"
                     /GO_function="GO:0004721 - phosphoprotein phosphatase
                     activity [Evidence IEA]"
                     /GO_function="GO:0004725 - protein tyrosine phosphatase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016470916.1"
                     /locus_tag="JJV70_RS07655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJV70_07665"
                     /product="tyrosine-protein phosphatase"
                     /protein_id="WP_219046998.1"
                     /transl_table=11
                     /translation="MTSEAVEPVLAGVRNFRDLGGLPTTDGRRVRQGMLFRSGHLARAT
                     DQDAAFLTRLGLHTVYDFRNDADIALDGTDVALPGVRNVNMPLTDPAHGVEFWKLVRDG
                     EVAVLREELADGRAVARMQESYADIVRTRTAEHGRVLRELAEGSVPVLMHCAAGKDRAG
                     LSVAITLLALGVEQEAIEADYLLSNAPHRRYEVHRGDGALEAEDRKGIDPEVRELLAPF
                     FDARPVYLATAYATIADVWGDVDTYLSRGLGLTDPLRGALRDRFLA"
     gene            15476..16159
                     /locus_tag="JJV70_RS07660"
                     /old_locus_tag="JJV70_07670"
     CDS             15476..16159
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019358576.1"
                     /locus_tag="JJV70_RS07660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJV70_07670"
                     /product="alpha-ketoglutarate-dependent dioxygenase AlkB"
                     /protein_id="WP_219046999.1"
                     /transl_table=11
                     /translation="MSAELFPRPAAGVAPGAVHLPGWLGADAQRELLAACREWAQPPAG
                     LRTVRMPRGGRMSVRQLSLGWHWYPYGYARTVVDGDGAPVKPFPTWLGQWARDAVRAAR
                     GVDDALGAAGDIAGTAGSTDIAYDIALVNFYDEHARMGPHRDSDERSGAPVVSFSLGDS
                     CVFRFGTAESRGRPWTDVELAGGDAFVFGGPARYAYHGVPRTRPGTAPPWLGLRGRVNV
                     TVRER"
     gene            complement(16176..18362)
                     /locus_tag="JJV70_RS07665"
                     /old_locus_tag="JJV70_07675"
     CDS             complement(16176..18362)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1025: diguanylate cyclase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018955705.1"
                     /locus_tag="JJV70_RS07665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJV70_07675"
                     /product="putative bifunctional diguanylate
                     cyclase/phosphodiesterase"
                     /protein_id="WP_374227255.1"
                     /transl_table=11
                     /translation="MNTGPKDTAGPGSPRPAGSGPHPDGLRRFATIWSRAVYPTTATCM
                     TRAEFEEHLVPLAELLGSTLHARPFDPGPARAVGTALVAAHCTAPEALPQILGVVDAYL
                     LLYCADPSELPPEEGRARCARLQHAIAAGFARALQERTRAEQESLSRAALAAQAEIERA
                     LHESETRFRAVFEGATIGIGIAALDGTVLETNSALYTMFGDCEQQLRARKVTSWVHPDD
                     GPSVWRMYDELVRGEREHFRTEKPYHRPDGTVLWTHLTVSLLRDPDGTPRYMLALMEDI
                     TERRLLHLRLRYEATHDALTDLPNRTLFFERLEQALARGAETRFGLCYLDLDGFKTVND
                     SLGHAVGDQLLVAVAERLQGCVNGSGQLIARIGGDEFVALVTDPSCSRDVTDLAERALE
                     ALSTPVLVDGRELPVRASIGIVDGPAGERTAAEVLRSADITMYRAKAQGGNRYELADPD
                     ADARVISRHSLTNRLPAALEGHEFFIEYQPLVRMSDGSVEGAEALVRWDHPRHGVLGPD
                     RFIPLAEHTGLIVPLGRWVLQEAVRQACEWQVRGIGGARPLRVNVNLSPRQLSHPDLVA
                     DTVAVLRNAGLPPHSLCLEVTESAMIRADDAELKPLRQLAELGVGIALDDFGTGYSNLA
                     SLRRLPASTLKLDRSFTRGLQQHPADPVDLKIVEGIVSLAHVLDLSVTVEGVETAAQAE
                     HLRALGCDSAQGWFYARPGPPEHMAVELPLAAVR"
     gene            complement(18359..19171)
                     /locus_tag="JJV70_RS07670"
                     /old_locus_tag="JJV70_07680"
     CDS             complement(18359..19171)
                     /EC_number="2.1.1.-"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1292: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003994563.1"
                     /locus_tag="JJV70_RS07670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJV70_07680"
                     /product="SAM-dependent methyltransferase"
                     /protein_id="WP_219047000.1"
                     /transl_table=11
                     /translation="MERPSWAPQGIDLSQPSVSRIYDYYLGGSHNFEVDREAARRAIEV
                     FPGLPKVMQANRAFMRRAVRYAVDEGITQFLDIGSGIPTFGNAHEVAQAAAPDARVVYA
                     DNDPVAVAHSRAVLEGNANTGVVAADFRDPQALLASEPVERLLDLERPVALLLVALLHF
                     IKDEEEPGKALAALRDRLAPGSLLILTHASTEGGPHSTEQGREVSDVYRSVGSRLLMRS
                     RAEVLAFFDGFELVEPGLVSMPNWRPDGPVDQEDPVVFTGFGGVGRKA"
     misc_feature    19260..19275
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.5"
                     /tool="antismash"
     gene            19423..19824
                     /locus_tag="JJV70_RS07675"
                     /old_locus_tag="JJV70_07685"
     CDS             19423..19824
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014056790.1"
                     /locus_tag="JJV70_RS07675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJV70_07685"
                     /product="ChaB family protein"
                     /protein_id="WP_219047001.1"
                     /transl_table=11
                     /translation="MPGRQELPSTLRRSPQGAQRTWVKAHDSAVETYGEGERAHRVAFS
                     ALKHSYEKVGDHWERKEGGRRGPSDPRAARPRQQGGRSGQGVDESASKRHLYEIAQRLD
                     IPGRSAMTKGELLSAIRKANRSVTRKARE"
     gene            20175..20420
                     /locus_tag="JJV70_RS07680"
                     /old_locus_tag="JJV70_07690"
     CDS             20175..20420
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003981675.1"
                     /locus_tag="JJV70_RS07680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJV70_07690"
                     /product="DUF6480 family protein"
                     /protein_id="WP_219047002.1"
                     /transl_table=11
                     /translation="MNDKNVLPPDPADREPKRSVGRPSGSGVPPGETPPAEGSTLDAGP
                     EETYNPTTGWARGPLIVIALIVVVFVGYFVARLFAT"
     gene            complement(20475..21560)
                     /locus_tag="JJV70_RS07685"
                     /old_locus_tag="JJV70_07695"
     CDS             complement(20475..21560)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: NAD_binding_4 (48-229). E-value:
                     1.1e-13. Score: 42.8. Matches aSDomain:
                     nrpspksdomains_JJV70_RS07685_NAD_binding_4.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NAD_binding_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010: NAD-dependent epimerase/dehydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014056976.1"
                     /locus_tag="JJV70_RS07685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJV70_07695"
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="WP_219047003.1"
                     /sec_met_domain="NAD_binding_4 (E-value: 3.2e-13, bitscore:
                     42.8, seeds: 102, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDSDGLRVVVTGASGNVGTSVLGALAAEPGVASVLGLARRVPQW
                     TPSKVRWASVDLGTEDAEAGLTGLLQGADAVIHLAWLIQPTHSPATTWRTNVVGTERVL
                     RAMATAGVPALVYSSSVGAYSPWPDPGKAERADESWPTHGWPQAAYTREKAYVERLLDA
                     FEREHPGIRVTRMRPAFMFKESSAMEQRRLFMGPFLPHRLVRPGVVPVLPDVPGMRFQV
                     LHTDDAATAFTRAVLRDVSGAFNLAAEPPIDARVLGDVLGARPVRLPPAPLRGALWAAW
                     RLRAVPASPYLFDAFLRLPLMDTSRAREELDWAPRRSGPQILAEFLRALRAGAGLPTPP
                     LRPHRAGGRLREFATSVKGRE"
     aSDomain        complement(20874..21416)
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_JJV70_RS07685_NAD_binding_4.1"
                     /evalue="1.10E-13"
                     /label="JJV70_RS07685_NAD_binding_4.1"
                     /locus_tag="JJV70_RS07685"
                     /protein_end="229"
                     /protein_start="48"
                     /score="42.8"
                     /tool="antismash"
                     /translation="KVRWASVDLGTEDAEAGLTGLLQGADAVIHLAWLIQPTHSPATTW
                     RTNVVGTERVLRAMATAGVPALVYSSSVGAYSPWPDPGKAERADESWPTHGWPQAAYTR
                     EKAYVERLLDAFEREHPGIRVTRMRPAFMFKESSAMEQRRLFMGPFLPHRLVRPGVVPV
                     LPDVPGMRFQVLHTDDAA"
     gene            21701..22042
                     /locus_tag="JJV70_RS07690"
                     /old_locus_tag="JJV70_07700"
     CDS             21701..22042
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="JJV70_RS07690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="JJV70_07700"
                     /product="hypothetical protein"
                     /protein_id="WP_257573576.1"
                     /transl_table=11
                     /translation="MQQPDPSRDPDAERAGLLGRVSPRTGREPARAHSALRLRWLLSLL
                     FTPLFIAGAVLFWAWSAASGPMDVPTDTSLRVLAGIFTFLAVFAFADLLVVQGRLHRAR
                     QRARRRAGH"
     misc_feature    22260..22270
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.59"
                     /tool="antismash"
     gene            22264..22710
                     /locus_tag="JJV70_RS07695"
                     /old_locus_tag="JJV70_07705"
     CDS             22264..22710
                     /NRPS_PKS="Domain: Polyketide_cyc (10-127). E-value:
                     2.9e-21. Score: 68.0. Matches aSDomain:
                     nrpspksdomains_JJV70_RS07695_Polyketide_cyc.1"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010033581.1"
                     /locus_tag="JJV70_RS07695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="JJV70_07705"
                     /product="SRPBCC family protein"
                     /protein_id="WP_219047004.1"
                     /transl_table=11
                     /translation="MSHIEESIELDVPVSTAYNQWTQFTDFPHFMEGVERVDQVTDTST
                     HWVTKIAGVEREFDADITEQIPDERIAWTSRNGPKQAGVVTFHHLTPGRSKVMLQLEYA
                     PEYFTEAVGDALGLVKRKAAGDLERFKKFIESRGTETGAWRGEV"
     aSDomain        22294..22644
                     /aSDomain="Polyketide_cyc"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_JJV70_RS07695_Polyketide_cyc.1"
                     /domain_subtypes="Polyketide_cyc"
                     /evalue="2.90E-21"
                     /label="JJV70_RS07695_Polyketide_cyc.1"
                     /locus_tag="JJV70_RS07695"
                     /protein_end="127"
                     /protein_start="10"
                     /score="68.0"
                     /tool="antismash"
                     /translation="DVPVSTAYNQWTQFTDFPHFMEGVERVDQVTDTSTHWVTKIAGVE
                     REFDADITEQIPDERIAWTSRNGPKQAGVVTFHHLTPGRSKVMLQLEYAPEYFTEAVGD
                     ALGLVKRKAAGDL"
     misc_feature    complement(22312..22326)
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: weak, score: 20.71"
                     /tool="antismash"
     gene            22936..23382
                     /locus_tag="JJV70_RS07700"
                     /old_locus_tag="JJV70_07710"
     CDS             22936..23382
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="JJV70_RS07700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="JJV70_07710"
                     /product="hypothetical protein"
                     /protein_id="WP_219047005.1"
                     /transl_table=11
                     /translation="MTEPNPESNDPGRNPEDEGIPDLQDGWPKAQQAEDPQQMPVPGDR
                     PVAAESHGTTPSEQREGESLDARLAQEEPDVDEETGAAGTPDPEAGQISDERLPGTPSG
                     DHLVGHESPAAGLPAEERALHIESMDEADAPPSDPEENPADEQR"
     misc_feature    24189..24204
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.0"
                     /tool="antismash"
ORIGIN
        1 gggaggccaa cactcgaagc acaggcggcc cggcggcgac gcgagcgggc cgcgcggacg
       61 cgtggagacg agggcgggtg ccggtcgata tggagagcag cgggagagcc ctgcagccac
      121 ccccggcggg tgcggtggcc tacgaaggca cctggcggtt caccgccccg gcgctggact
      181 cctcggtgcc gcgggtgcgg cacgcggtgc gggatctcgt cagacggcag ggcgcgcccg
      241 tctccaccga ggtgatggat ggcctgctgc tcatcgtctc cgagctggtg acgaactccg
      301 tgcggcacgc ggcgctgctc tcgcccgagc tgggcgtcga gatgtcgatc ggctctgggt
      361 gggtgcgggt ggccgtcgag gacggacacc cctaccggcc gaaggcgctg gccgccgacc
      421 cggccctgga gcacgtgggc gggcgcgggc tgctgctggt gaaagcggtg tgcgcggagt
      481 tcgccggcac atgcgacgtc gagcagacgg cggcgggcgg caaggtcatc tgggcgtgcc
      541 tgccgctgtg ggcaccggca ccggcgtagc ccgcacgtga gggtgcctgc ccgtgagccc
      601 gaagaccccc ggacagggcg ccggaagacc gcccggggca gcacgccgaa ggcgcgcccc
      661 cgcagcacac gagcgccccc gcctcctcgc gaggaacggc ctaccacccg gcctcggggg
      721 ccaccgcgcg gatgccgtcg cgggccgcgt cgaggacggt caggaaccag gcggagaacg
      781 ggtcgcgcgc gtgccgcgcg gccagttcgt ccggggtgac gaaggcggtc tccgcgatct
      841 cggcggggtc gggccggggc tccgcccgca ccagtccggc gaacaggtgg ttgtactcgc
      901 tctccaccag ccccgacgcc gggtccgggt gccggtaggt caccgtgccc gcctccgcca
      961 gcagcacggg cgccaccccc agctcctcgc cgacccggcg ggccgccgcc acgaacggcg
     1021 gctcgccggg ataggggtgc ccgcagcagg tgttggacca cacgccgggg gagtggtact
     1081 tgcccagcgc gcggcgctgg agcagcaggc gtcccgtgtc gtcgaagagg aagaccgaga
     1141 acgcccggtg cagatgtccc ggcggctggt gcgcggagag cttctccgcg gtgccggtcg
     1201 tcacgccgtc ctcgtcgacc agttccagca tgatcggagt tgtcatggcg tcagtcatac
     1261 cgatcctcgt cttccggggg ctctccccag tgtgcgtgat cgggcgcccg ccagctgtca
     1321 cccgcggggt cagtggcaca cctgggcctc gtgcgcccag tggccgcgcg gttcgagctg
     1381 gaacgtgcag tgcgcgacgt cgaagtgggc gcccagacac gcctggaggt cgtgcagcac
     1441 ccggtcgtgc tcaccggctt ccagcagctt gtcctcgacc acgacgtgca ccgacagcac
     1501 gggcatgccc gaggtgatgg tccacacgtg caggtcgtgc agggactcca ccccggtgac
     1561 gtcgaggatg tgccgccgca cttccgccac gtccacgtcc ttgggcgccg cctccagcag
     1621 cacgtccagc gcctcccggg ccagcttcac tgtgcgcggt acgatcatca gcgcgatgat
     1681 cagggaggcg accacgtcgg cccgcgtcca gccggtgacg atgatcacta gcgcggaggc
     1741 gacgacggcg agcgagccga gcgtgtcggc cagcacctcc aagaaggcgc cgcgcacgtt
     1801 caggctctcc ttctgccccc gcatgagcag cagcagcgac aggcagttca gcgccaggcc
     1861 gatcacaccg acgatgacgg ttgggacacc cggtacctcg gcgggttcct ggaaccgttt
     1921 caccgcctcc accacgatgt aaccgcccac cccgagcagc agcacgcagt tcagcagcgc
     1981 ggccagaatc tctgcccggg cgaagccgaa ggtgcgccgt tcggacgccg gccgggcggc
     2041 gaagccgatg gcggcgagcg cgacggcgat gcccgtggcg tcggtcgcca cgtgcccggc
     2101 gtcggcgagc agggccagcg aaccggtcag ccaggctccg acgagctgca ccaccagcag
     2161 ggtgacggcg atcaccagcg cgatcagcag ccgcccccgg tacgccgccg aagcggtgcc
     2221 ggacgttccc ggtgatggcc ctgtgtggtg gtgccccgcg cccatgcgca cgcctcccgt
     2281 tcctcggtta cggaccccag tgaactacgg gtcgggggta tgggcaacgc ggcattgaac
     2341 accgttgtca tgtgccctga cctgcgactt tgtcgcgcag ctcagagcgt tgcgacccgc
     2401 ttgcacccgg ctgcgcgggt gcccggccgc gcgcgtgcgg ccggagcgtc cgaccggccc
     2461 tggcgccccg agcacccgcg ctcgccgcgc acgtcacacc ggtcgccaga accaaaggcc
     2521 gcgtaacgcg ggcaaccccg agccgctgaa cgggtgatga acagccgctt gtgaaatcgg
     2581 atagcctctg ccgggcaaac accgccaccc cctcggctga acaggcggtc ggtgcgccgc
     2641 ccggcgctgc cccgctctca gccggagacc ggccgcacct cacgcaccgg cccgctgtca
     2701 aggagtgagt ccgcctgccg accgccatcc tcaccggccc cccggccgcc ggatcgacgc
     2761 tcgagggcga cctgcggtcg ctcggcttca ccgtgcggac cgccgccgca ccgtccggcg
     2821 tcgccgcgct cctggccgcc gtgccggcgg cggagcgggc cgcggtcgtt gaccaccgct
     2881 tcaccgggca cccgcacagc ctgcgcctgg cgctgaccga tccgcgtttc ccggccgccg
     2941 cgatccccgg tgccgtcacc gcccagccgc aggcccgcgg cgctctcgcc cgtgctgtgg
     3001 ccgctgaccc cgacccccag gccgtccccg ccgccctgga gaccgctggc gtcccggtgc
     3061 accggcccga cctcggcgtg ctcgtcgccg ccgtccccgc cgacgccgag gcgctggccg
     3121 ccgcccgcgc cgccaccgcc gccgtggacg acgagcgggt gcggctgcgc tcggccgtga
     3181 agtcccgcga tgggttcttc accacgttct tcatcagccc gtactcgcgc tacgtcgccc
     3241 gctggtgcgc ccggcgcggt ctgaccccca accacgtcac cacggcatcg ctgctggtcg
     3301 ccctgctcgc cgcggcctgc gccgccagcg gcacccgggc aggcttcgcc gcgggcggcg
     3361 tgctgctcat cgcctccttc ctgctggact gtgccgacgg ccagctcgcc cgctacgcgc
     3421 tgcgctactc cacgctcggt gcctggctgg acgccacctt cgaccgggcc aaggagtacg
     3481 ccttcctggc cgggctcgcg ctcggcgcgg cccgtggtgg cgatgacgtg tgggcgctgg
     3541 cactgggcgc catggtgatc cagaccgtcc ggcacgtggt cgatttctcc ttcaccgagg
     3601 gcaaccacta cgaaacgtcc gccggcccac aaggtgccga taccggcggt gcggggcacg
     3661 ccagccccac cgccgccctg tccgggcgcc tggaccgcgt cggctggacg gtgtgggcgc
     3721 gccgcatgat cgtgctgccc atcggtgaac gctgggcgct gatcgccgtg ctcaccgcgc
     3781 tcaccacgcc gcgcaccacg ctggtcgtcc tcatcgccgg gagtgtgctc gccgcctgct
     3841 acaccaccgc gggccgcgtg ctgcgctcgg tcacccggca agctccccgc accgtggggg
     3901 ccgcccgcgc cctggccgac ctgtgcgacg ccggtccgct cgccgagctg gccgcccgca
     3961 ccgcgccgcc cgcccggcgt ctcgccccgg tgttcgccgc gctcggcgcc gtcgccgtcg
     4021 ccggcgccgc gctgtgggca ccggcgggct cctggattcc cgtggccgcc gccgcgctgt
     4081 acgtgctgct gtccggctgg gccgtcgcac gcccgctggc cgggccgctg gactggctgg
     4141 tcccgccact cttccgggcc gccgagtacg gcacggtgct ggcgctggcc gcttcgtccc
     4201 aggcgaacgc ggcgcccggg gtaaacaccg cgttgccagt ggctttctgc ctggtggcgg
     4261 cggtcgccta ccatcactac gacacggtgt accgcatccg cggtggcgcc ggggccccgc
     4321 cccggctgct ggtgcgggcc gtcggggggc aggagggccg caccctgctg gtcaccgtcg
     4381 ccgccgccct gtggtccggc ggcaccggct tccccctcgc gctctcggtg ctcgccggga
     4441 ccgtggctct cgtggtgctc gccgagagca tccgcttctg ggtgtccgcc gcggcgcccg
     4501 cagtacacga cgaaacagga gtacccgcat gatcggcctc gtgctggccg ctggcgccgg
     4561 acggcgtctg cgtccctaca ccgacaccct ccccaaggcg ctcgtacccg tggacggcga
     4621 gaccaccgtg ctcgacctca ccctgggcaa cttcgccgag gtcggtctca ccgaggtcgc
     4681 catcgtcgtg ggctaccgca aggaggccgt gtacgcgcgc aaggaggagc tggagagccg
     4741 ttacggtctc aagctcaccc tgatcgacaa cgacaaggcc gaggagtgga acaacgccta
     4801 ctccctgtgg tgcgcgcggg atgtcatcaa gcagggtgtg atcctggcca acggtgacac
     4861 cgtccacccg gtctccgtcg agaagacgct gctcgcggcg cgcggcaagg gccagatcgt
     4921 gctcgcgctg gacaccgtca agcagctcgc cgacgaggag atgaaggtcg tcaccgacga
     4981 cagcggcggc gtccgcaaga tcaccaagct gatggacccg gccgaggcga ccggcgagta
     5041 catcggcgtc accctcatcg agggcgaggc cgccgaggcg ctggccgacg cgctgcggac
     5101 caccttcgag cgcgacccgg acctgtacta cgaggacggc taccaggagc tggtcagccg
     5161 tggcgtcacg attgacgtcg agcccatcgg ggacgtgcgg tgggtcgaga tcgacaacca
     5221 cgacgacctc gccaagggcc gggagatcgc gtgccagtac tgacccggct catcccctcg
     5281 ccggtcgtcg tcgatatccg ccggggcgcg ctggaggacc tggcctcagt gctggccgac
     5341 gagcggatct ccgcctccgg cacgctggcc gtcgccatca gcggcggctc cggcgcggcg
     5401 ctgcgtgaac gcctcgcgcc cgcgctgccc ggcgcgagct ggtacgaggt cggcggcggc
     5461 acgctggacg acgcggtcaa gctcgccgac gccatgaagt caggccgcta cgacgcggtc
     5521 gtgggcctgg gcggcggcaa gatcatcgac tgtgccaagt tcgccgccgc ccggatcggc
     5581 ctgcccctgg tggccgtcgc caccaacctc tcgcacgacg gcctgtgctc cccggtggcc
     5641 acgctcgaca acgacgcggg gcgcggctcc tacggcgtgc cgaacccgat cgccgtcgtc
     5701 atcgacctcg acgtcgtgcg ccaggcaccc agccgcttcg tgcgctccgg catcggagac
     5761 gtgatctcca acatctccgc cgtcgccgac tgggaactct cccaccgggc caccggcgag
     5821 aagatcgacg ggctcgccgc cgccatggcc cggcaggccg gtgaggccgt cctgcgccac
     5881 cccggcgaca tcggcgacga cggcttcctc accgtgctcg ccgagggcct ggtactcacc
     5941 ggtatctcca tgtcggtggc cggcgacagc cgtcccgcct ccggcgcctg ccacgagatc
     6001 aaccacgcct tcgacctgct gtaccccaag cgggccgcca gccacggcga gcagtgcggc
     6061 ctcggtgccg ccttcgccat gcacctgcgc ggcgcgcacc aggagtgcgg cctgatggtg
     6121 gaggtgctgc gccgccacgg ccagccggtg ctgccgcagg acatcggctt cggcgtcgag
     6181 gagttcgtca cggccgtgga gtacgccccc cagacccggc ccgggcggta caccatcctc
     6241 gaacacctcg acctgtccac cgaccagatc agggacgcgt acgccgacta tgccaaagcc
     6301 atcggtagct gaactcaggc cggtcgtcca ccccgagggc gtcaaggacc ggcgcagcgg
     6361 cgagcactgg gccgggcggc tctacatgcg cgagatctcc ctgcgcgtgg accgccacct
     6421 ggtaggcacc cgcgtcacac ccaaccagct cacctacgtg atgacactcg cgggcgtcct
     6481 cgccgccccc gcgctgctgg tgccggggat ctggggcgcc gtcctcggcg tggtgatggt
     6541 ccagctctat ttgctgctcg actgtgtgga cggcgagatc gcgcgctgga agcggcagtt
     6601 ctcgctcggc ggggtgtacc tggaccgagt cggcgcctac ctgtgcgacg ccgccgtgct
     6661 ggtcggcttc ggcctgcggg ccgccgaccc ctggggcacg gggggcgtgg agtggctgtg
     6721 ggccttcctg ggcaccctcg ccgcgctcgg cgccgtcctg atcaaggcgg agaccgatct
     6781 cgtcgctgtc gcccgccacc agggcgggct gccgccggtc caggaagcgg cgtccgaacc
     6841 gcgctcgtcc gggctggcac tggcccgccg cgccgccgcc gcgctgaagt tccaccggct
     6901 ggtcctcggc atcgaggcgt cgctgctgat cctgctcctg gccatcgtgg acgccgcccg
     6961 gggcgacctg ttctacaccc ggctcggcgt ggccgtgctc gccgccatcg cgctgctgca
     7021 aaccctgctg cacctggtgt ccgtcctggc ctccagcagg ctccggtgag cggcggcccg
     7081 gcgggcacgg ccccgctccg gctcggcgcg gtgatcctca ccatgggtga ccggcccgcg
     7141 gagctgcgcg cgctgctgga gtccgtcacc cggcaggacg gtgacccggt acaggtcgcc
     7201 gtcgtcggca acggcgcccc gctgcctgag ctgcccgacc tccccggcgg cctgcgcacg
     7261 cgggaactgc ccgagaacct gggcatcccc ggcgggcgca acgcgggcgt cgagctgttc
     7321 gggaccgggg ggcgcgaggt ggacgtcatc ctcttcctgg acgacgacgg gctgctcccg
     7381 cgcgccgaca ccgccgagct gctgcgccag gcgttcgccg acgacagcca gctgggcatc
     7441 gtcagcttcc gcatcgccga ccccgcctcc ggcgagaccc agcgccgcca cgtgccccgg
     7501 ctgcgcgccg ccgccccgat gcgctcctcg cgcgtcacca ccttcctcgg cggtgccagc
     7561 gcggtgcgca cggccgtcct ccagcaggtc ggcgggctgc ccgacgactt cttctacgcc
     7621 cacgaggaga ccgacctcgc ctggcgggcg ctggacgccg ggtgggagat cgactaccgg
     7681 gccgacctcg tcctgcacca cccgaagacg ctgcccagcc gccacgcggt ctaccaccgc
     7741 atggtggcgc gcaaccgcgt gtggctggcc cgccgccgcc tgccgctgcc gctcgtcccc
     7801 gtctacctcg gcgtgtgggt gctgctcacc ctgctgcgcc gcccctcccg cgccgcgctg
     7861 cgcgcctggc tgggcggttt ccgcgagggc tgggcgaccc cgtgcggtcc ccggcgcccc
     7921 atgcgctggc gtacggtgtg gcgcatgacc cggctgggac gacctcccgt catctgaaat
     7981 gctcgggtct gagaacatca gcacccggcc ccctccacac cagaggacgt aagtttcacc
     8041 gtgagcgagt ctgcgcacga acgtgcggtc gccatgcacg cgccccctca tcccgacgac
     8101 gccctgacgc ctgcccagct ggcggataag tacgggctga gcgtcagcgg cgcgcgccct
     8161 tcgctgcccg agtacgtccg gcagctgtgg caccggcggc acttcatcgg agccttctcc
     8221 cgggccaagc tgcaggccca gtacagccag gccaagctcg gccagctctg gcaggtcgcc
     8281 accccgctgc tgaacgcggc ggtctacttc ctgatcttcg ggctgattct gaacggcagg
     8341 gagggagtgc ccggcggtga cggtaactac gtgccgtttc tggtgatcgg ggtgttcgtc
     8401 ttcaccttca gccagcagtc ggtgctctcg ggcgtgcggg ccatctcctc caaccagggt
     8461 ctggtgcggg cgctgcactt cccccgcgcc tcactgcccc tggccttcgt gctccagcag
     8521 ctccagcagc tgctgtactc gatggtggtg atgctggtcg tgctgctggc cttcggacag
     8581 cgcccgggtc tgtcctggct gctggtgatc ccggtgctgg gacttcagtt cgtcttcaac
     8641 ggcggcctgg ccatgatctt cgcgcgcctc ggcagcagca ccccggacct ggcccagctc
     8701 atgcccttcg tgctgcgcac ctggatgtac gcctccgggg tgatgttccc gctgcaccac
     8761 atgctggtga ccaacgcgaa actgccggtg tgggcggccg acctgatcgc ggccaacccg
     8821 gccgcggtgt tcatggacct gatgcgtttc gcgctcatcg acgactacac ctacgccgac
     8881 ctcacgcctt tcccgtggct tctggccctg ggctgggcgc tgctcgccgg ggtgttcggc
     8941 ttcgtctact tctggaaggc cgaggagcgg tatggccgtg gctgacccga cgacccccac
     9001 gaacctggcg aaagccccgc aggcaccgga ccggcgtccg acggtcatcg cggacgacgt
     9061 gcacatcgtc taccgggtct atggcggcgc gcgcggcaag ggcagcgcga cggcggcact
     9121 gaaccggatc atgcggcgca agcccggcgg cggccgggtg cgcgaggtgc acgccgtcaa
     9181 gggcgtgagc ttcaccgcct accggggtga ggccatcggg ctgatcggct ccaacgggtc
     9241 gggcaagtcc acgctgctgc gcgccatcgc cgggctgctg ccgcccgagc gcggcaaggt
     9301 ctacaccgac gggcagccct cgctgctcgg cgtcaacgcg gcgctgctca acgacctcac
     9361 cggcgagcgc aacgtcgtgc tgggcggcct ggcgatgggc atgtcccgcg aggagatccg
     9421 cgcgcgctac caggacatcg tggatttctc cggcatcaac gagaagggtg acttcatcac
     9481 cctgccgatg cgcacgtact cctccggcat gtccgcgcgg ctgcggttct ccatcgccgc
     9541 cgccaaggat cacgacgtgc tgatgatcga cgaggcgctg gccacgggcg acaagaagtt
     9601 ccagaagcgc tcggagaacc gcatccggga actgcgcagg gaggccggga cggtcttcct
     9661 ggtcagccac aacaacaagt cgatccggga cacctgcgac cgggtgctgt ggctggagaa
     9721 gggcgaactc cgcatggacg gcccgaccga ggtcgtcatg aaggcctacg aggagttcac
     9781 cagcaagtaa tccgtcccgg ggtacctccc ggcggtagtt gaggggttcg aggagagcgc
     9841 cgggcgtcgc tctcgcggcc cgggcggagc cccagttccg ggaggggcgc ccacccctcg
     9901 cccgcccagc gacaaccccc ccccgcgtgt ctgaaatgca gattatctgg caatcaaggt
     9961 agaaacgagg cgtgacggca gtggagaggg gccacgcgtg gtgaccgcct ggacgcccac
    10021 ggcacaggcc cccgtgcgcg gcgtgctcga ccaggcggcg gcggagaact tccccgtggc
    10081 ccccgccttc ctgcccgccg ccgggcgcgc cgccctgctg gccgtctacg gctacgcccg
    10141 gctggtggac gacatcggcg acggcgatct ggcccccggc ggcgccgacg cccgcctgtt
    10201 cggcgtcccg cccgagcacg ccgaggaccg gcccgccctg ctggacgccg ccgaggcgga
    10261 cgtccaccgt ctgctggacg ccgcgcggtg gcccggagcg ccaggcccgc gtcacccgct
    10321 ggtgcgcgcc ctgctccccg ccgtccgggc ccacgcgctg accgccgagc cgttcctcgc
    10381 actgatcgag gcgggccgac tcgaccagca ccgccacacc tacaccacct gggaagaact
    10441 gctcggctac tgcgcgctgt ccgcccaccc ggtgggccgc ctggtgctcg ccgtcaccgg
    10501 caccgcctca cccgagcggg tgcgccgctc cgacgcggtg tgcaccgcgc tccaggtcgt
    10561 cgaacacctt caggacgtgg ctgaggaccg cgcccgtggc cgcgtctacc tcccggccga
    10621 ggacctggcc cgcttcggcg tgcgcgaggc ggacctggac gcaccggtca cctgcgcggc
    10681 gctgcgcagc gtcgtcgcct gcctggcgga acgttccttc gcactgctgg acgaaggcac
    10741 cggcctggtg gcgagtgtgc cggggcggct gcggctgctg ctggccggat acgccggcgg
    10801 aggccgcgcg gccctgcgcg cgctggccgc cgcccgctac gacgtcctgg ccgggccccc
    10861 caccgcggcc cgtcccgccg tgctgcgcga gacggcggca gtcctgatgg ccgcccgacg
    10921 agtccgatga ggaggccctc gatgaccccg gccaccagcg cccccacgac ccccgacccc
    10981 acgggggaat cctcagcccc tggcggcgcc ggccccggcc cccaggagcc gcccgcgccc
    11041 gtgctggccg cctacggcta ctgcgagacc gtcaccgctc agcaggcccg caacttcgcc
    11101 tacggcatcc gcctgctgcc cccgcccaag cgccgcgccc tgtccgccct gtacgccctc
    11161 tcccgccgcg tggacgacat cggcgacggc ttcctggacg ccgacaccaa aaccgcccgg
    11221 ctcgccgacg cccgcaccct gctcgcgcgc gtccgcgacg gcgccgtggc cgccgacgac
    11281 accgatccgg tggccctcgc cctcaccgac gccgcccacc gctacccggt gccgctggac
    11341 gccttcgacg agctgatcga cggcgtcctg atggacgtga ccgcccgcac ctaccgcacc
    11401 tgggacgacc tgcgcgacta ctgccgctgc gtcgccggag ccgtcgggcg gctcaccctc
    11461 ggcgtcttcg gcaccgcgcc cggcgccccg gacgccgccc gcgcccccga gtacgccaac
    11521 accctgggcc tggccatgca gctcaccaac atcctgcgcg acctgcgcga ggacgcccgc
    11581 agcggccgca gctacctgcc ctacgaggaa ctggcggcat tcggctgcgt gggcgccttc
    11641 gacgcggcca ccgccccacc cggcgccgac ctcaccggcc tcgtacacca ccaggcccgc
    11701 cgcgcccggc ggctgttcgc cgagggctac cggctgctgc cgcagctcga ccggcgctcc
    11761 gccgcctgcg tggcggccat ggccgggatc taccgccgcc tgctggaccg catcgaggcc
    11821 gacccggccg ccgtgctgcg cggccgggtc agcgtcccgc cccggcagaa ggccctcacg
    11881 gcggttcgcg gcctgaccgg gctcgacgcc gcgctggtgc gccgtgccat ccgccggagc
    11941 gcccggtgag cgacacgctc gccccggaag gcggccaggc gcccgcccga ggcagcgccg
    12001 tcgtcgtcgg cggcggactg gccggaatca ccgccgccct gcggctggcc gacgccgggg
    12061 taaccacgac gctgctggaa gcccggcccc ggctcggcgg gctggcgttc tccttccgcc
    12121 gcgagacccc ggccggagtg ctcaccgtgg acaacggcca gcacgtgcac ctgcgctgct
    12181 gcaccgccta tcgctggttc ctggaccgcg tcggggcccg ggcgctggcc ccgctgcaac
    12241 gccgcctgga catccccgtg ctggacgctc gcacccgccg cgtcggccgc atccggcgca
    12301 ccgccgcccc ggtgccgctg cacctcgcga ccgccctcgc ccgctacccg cacctgaccc
    12361 cggccgaccg cctgcgcgct gcccgcgccg cgctcgccct gcgccgtctg gacccggccg
    12421 acccggcgct ggacggtcag gacttcggca cctggctgcg ccgccagggc cagtcaccgc
    12481 gcggcatcga ggcgctgtgg gacctggtgg gcgtggccac gctcaacgcc cgcgcccgcg
    12541 acgtctcgct cgccctggcc gccatggtct tccgcaccgg cctgctcagc gacgccggtg
    12601 ccgcggacct cggctgggcg cgcgtcccgc tcggcacacc gcacgacacc ctcgcccgcc
    12661 gcgcgctcac ttcggcgggc gtcaccgtgc gcaccggggt gcgggtgcgc gggctcgggc
    12721 agcaccccgg cggacgctgg cacctggaca ccggccgcgc ccccggagtc tccccggagt
    12781 ccgccgacgc cgtggtgctg gcggtgccgc aggaccgggc cgccgccctg ctgcccaccg
    12841 gcgccctgcc cgatgcgggc cgcctcgccc gcatcggcac cgcgccgatc gtgggcgtgc
    12901 acgtcctgta cgaccgcccg gtgctgcgcc gccccttctt cgccgccctc ggcagcccgg
    12961 tgcagtgggt gttcgaccgc actcccgcct gcgggctcgc cccggacagc ggccagtacc
    13021 tcgccctgtc ccagtccgcc gcgcacgccg acatcgacgc ccccgtccgc gtcctgcgcg
    13081 agcgctacct ccccgcgctg gcccggctgc tgcccgccgc ccgtaccgcc cgcgtccgcg
    13141 cgttcttcgt cacccgcgag cggcacgcca cgttcgcgcc cgggccgggg gtcgagcgcc
    13201 tgcggcccgc cgcgcacacc aacgcaccgg gcatgtacct tgcgggcgcg tggtgtgcca
    13261 ccgggtggcc cgcgacgatg gaaggcgcgg tccgcagtgg ccacgccgcc gcgcgcgcgg
    13321 cgctggcccg cctcgggcac ccgcccggcg acaccccctg ggagtcgccg tcaggacgac
    13381 cgctgaacgc gaaggagacc ctgtgaaccc ggtgcaaccg gcccccgccg gcatcgactc
    13441 ggccgcggtg accgctctgc tcacccgcgg gcgcacgctg ccgcagcccc tgctccgggc
    13501 cgccgtggcg cgcctcgcgc cgcccatgga cacggtcgcc gcctaccact tcggctggat
    13561 cgacgccgag ggccgccccg ccgacggcga cggcggcaag gccgtgcgtc ccgccctcgc
    13621 cctgctgtcc gccgaagccg ccggcgccgg gcccaagacc ggtatccccg gcgccgtcgc
    13681 cgtcgaactg gtacacaact tctccctcct gcacgacgac ctcatggacg gcgacgagca
    13741 gcgccgccac cgtgacaccg tgtggaaggt ccacgggccc gcacaggctg tcctcgccgg
    13801 cgacgcgctg ttcgcgctgg ccggggagat cctgctggaa ctcggcaccg ccgacgccgc
    13861 ccgcgccacc cgccgcctga cccgtgccac ccgcgcactg atcgacggcc aggcgcagga
    13921 catctcctac gagcaccggg aacgggtcac cgtcgaggag tgcctggaga tggagggcaa
    13981 caagaccggc gcgctgctgg cctgctccgc ctccatcggc gcggtgctcg cgggcgccga
    14041 cgacccaacc gccgacgcgc tgggcgccta cggccaccac ctgggcctgg ccttccaggc
    14101 cgtggacgac ctgctgggca tctggggcga cccgcaggca accggcaagc agacctggag
    14161 cgacctgcgc aagcgcaaga agtccctgcc ggtcgtcgcc gcgctcggcg gcggcggcgc
    14221 ggcggcgcgg cagctcggcg agctgctgac ggccgacgcg aagaagccgc aggccgaggt
    14281 tgacgacttc gacgaggcgc agttcgcgac gcgggcggcg ctgatcgagg aggcgggcgg
    14341 gcgcgactgg acggcggccg agtcccgccg acagcacggg gccgcggtgc gcgcggtctc
    14401 caccgtcgcg atgccgtccg cggtccgcgc gcagttcctc gccctggccg acttcgtcgt
    14461 ggaccgccag cggtagcccc cgcccctccc cggcctccgg cccctttggc agtcctgccg
    14521 cccagggtgc tggggaggcc aggggctcag gggctaggcc aggaagcggt cgcggagggc
    14581 cccgcgcagg gggtcggtca ggcccaggcc ccgggacagg taggtgtcca cgtcgcccca
    14641 gacgtcggcg atcgtcgcgt acgccgtggc caggtacacc ggccgcgcgt cgaagaacgg
    14701 cgccagcagt tcccgcacct cggggtcgat ccccttgcgg tcctccgcct ccagcgcacc
    14761 gtccccgcgg tgcacctcgt agcggcggtg cggggcgttg gagagcagat agtccgcttc
    14821 aatggcctcc tgctccacgc ccagcgccag cagggtgatc gcgacggaca ggcccgcgcg
    14881 gtccttgccc gccgcgcagt gcatcagcac gggcacgctg ccctcggcca gctcgcgcag
    14941 gacccggccg tgctcagcgg tgcgggtgcg cacgatgtcg gcgtagctct cctgcatgcg
    15001 cgccaccgcg cgcccgtcgg ccagctcctc gcgcagcacc gccacctcgc cgtcgcgcac
    15061 aagcttccag aactccaccc cgtgggccgg gtcggtcagc ggcatgttga cgttccgcac
    15121 gccgggcagg gcgacgtccg tgccgtccag ggcgatgtcg gcgtcgttgc ggaagtcgta
    15181 gaccgtgtgc aggccgagtc gggtgaggaa ggccgcgtcc tggtcggtgg cgcgggccag
    15241 gtggccgctg cggaacagca tgccctggcg cacccggcgc ccgtccgtgg tcggcaggcc
    15301 gccgagatca cggaagttgc gtaccccggc gagcacgggc tccacggctt cggacgtcac
    15361 gggcggctcc tcacacgaag gcgggcacag atgatcacac tgaacggcgt accttcccga
    15421 cgatacgaca gcggttaccc ggcagtcagc cagccggggt gcctacgctg gccgggtgag
    15481 cgccgaactc ttcccgcgcc ccgccgccgg ggtggcgccc ggggccgtcc acctgcccgg
    15541 atggctcggg gcggacgccc agcgcgagct gctggccgcc tgccgggagt gggcacaacc
    15601 gccggccggg ctgcgcacgg tgcgcatgcc gcgtggcggg cggatgtcgg tgcgccagct
    15661 cagcctcggc tggcactggt acccctatgg ctacgcccgc accgtcgtgg acggcgacgg
    15721 agctccggtc aagccgttcc ccacctggct gggtcagtgg gccagggacg cggtgcgcgc
    15781 ggctcgcggg gtggacgacg ccctgggggc cgccggggac atcgccggca ccgccggcag
    15841 cacggatatc gcgtacgaca tcgcgctggt caacttctac gacgagcacg cgaggatggg
    15901 cccgcaccgc gacagcgacg agcgctctgg ggcgcccgtg gtctccttca gcctcggcga
    15961 cagctgtgtc ttccggttcg gtaccgccga aagccgcggg cggccctgga cggacgtgga
    16021 actcgccggg ggtgacgcct tcgtcttcgg cggaccggcg cgctacgcct accacggagt
    16081 gccgcgcacc cggcccggca ccgcaccgcc ctggctgggg ctgcgggggc gggtgaacgt
    16141 gacggtccgc gagcggtgac ggcactcgcg gacggctagc gcacggcggc cagcggcaac
    16201 tccaccgcca tgtgctccgg ggggccgggg cgggcgtaga accagccctg cgccgagtcg
    16261 cagcccagcg cccgcaggtg ctcggcctgc gccgccgtct ccacaccctc gaccgtcacc
    16321 gacaggtcca gcacgtgggc cagcgagacg ataccctcga cgatcttgag atcgaccggg
    16381 tccgccggat gctgctggag gccacgggtg aaggaacggt ccagcttcag cgtgctggcc
    16441 gggagccggc gcaggctggc caggttggag tagccggtgc cgaagtcgtc cagcgcgatg
    16501 cccacgccca gctccgcgag ctgccgcagc ggcttcagct cggcgtcgtc ggcccggatc
    16561 atcgcggact cggtcacctc caggcacagc gagtgcggcg gcagcccggc gttccgcagc
    16621 accgccacgg tgtccgccac caggtccggg tggctcagct gacgcggcga gaggttgacg
    16681 ttgacgcgca gcgggcgggc gccgccgata ccgcgcacct gccactcgca cgcctgccgc
    16741 accgcctcct gcagcaccca gcggcccagc ggcacgatca gcccggtgtg ctcggccagc
    16801 ggaatgaacc ggtccggccc cagcacgccg tgccgcggat gatcccagcg caccagcgcc
    16861 tccgcgccct ccacgctgcc gtcgctcatc cgcaccagcg gctggtactc gatgaagaac
    16921 tcatgcccct ccagcgcggc gggcagccgg ttggtgaggc tgtgacggct gatgacccgc
    16981 gcgtcggcgt ccgggtcggc cagctcgtag cggttgccgc cctgcgcctt cgcccggtac
    17041 atggtgatgt ccgcgctgcg cagcacctcc gccgccgtcc gctcgcccgc cggaccgtcc
    17101 acgatgccga tgctcgcgcg caccggcagc tcgcggccgt ccaccagtac cggcgtggac
    17161 agcgcctcca gggcccgctc ggccaggtcg gtgacgtctc gcgagcagga agggtcggtg
    17221 accagggcca cgaactcgtc acccccgata cgggcgatga gctggccgga accgttgaca
    17281 cacccctgca gccgctcggc gacggccacc agcagctggt cgcccaccgc gtggcccaga
    17341 ctgtcgttga ccgtcttgaa gccgtccaga tccaggtagc acagcccgaa acgggtctcg
    17401 gcgccccggg cgagtgcctg ctccagccgt tcgaagaaca gggtgcggtt gggcaggtcg
    17461 gtcagcgcgt cgtgggtcgc ctcgtaccgc agccgcaggt gcagcaggcg gcgctcggtg
    17521 atgtcctcca tcagcgccag catgtagcgc ggggtgccgt ccggatcgcg gagcagcgac
    17581 accgtcaggt gcgtccacag caccgtgccg tcggggcggt gatagggctt ctcggtgcgg
    17641 aagtgctccc gctcgccgcg caccagctcg tcgtacatgc gccacaccga cgggccgtcg
    17701 tccgggtgca cccagctggt gaccttgcgg gcccggagct gctgctcgca gtccccgaac
    17761 atcgtgtaca aggccgagtt cgtctccagc accgtgccgt cgagtgccgc gatgccgatg
    17821 ccgatcgtcg cgccctcgaa caccgcgcgg aaccgcgtct cgctctcgtg cagcgcccgc
    17881 tcgatctccg cctgcgcggc cagtgccgcc cgcgacagtg actcctgctc cgcccgcgtg
    17941 cgctcctgca gggcccgcgc gaagcccgcc gcgatcgcgt gctgcaaccg ggcacagcgg
    18001 gcgcggccct cctccggcgg cagctcggag gggtccgcgc agtacagcag caggtacgcg
    18061 tcgacgacgc cgaggatctg cggcagcgcc tcgggcgccg tgcagtgcgc ggcgaccagc
    18121 gccgtgccca ccgcgcgggc cggcccgggg tcgaagggcc gggcgtgcag cgtggagccg
    18181 agaagttcgg cgagcggtac cagatgctcc tcgaactccg cccgcgtcat gcacgtcgcc
    18241 gtggtcgggt agaccgcccg gctccagatc gtcgcgaagc gccgcagccc gtcggggtgc
    18301 gggccggaac cggccgggcg gggcgaaccc ggcccggccg tatccttcgg acctgtgttc
    18361 acgctttgcg tcccactccg ccgaacccgg tgaacaccac cgggtcctcc tggtcgactg
    18421 ggccgtccgg acgccagttc ggcatcgaga ccaggccggg ctccaccagc tcgaacccgt
    18481 cgaagaacgc cagcacctcg gcgcgcgagc gcatcagcag gcgcgagccc acactgcggt
    18541 acacgtcgga gacctcccgc ccctgctcgg tgctgtgcgg cccgccctcg gtggaggcgt
    18601 gcgtgaggat cagcagcgaa cccggcgcga gccggtcccg cagcgcggcc agcgccttgc
    18661 cgggctcctc ctcgtccttg atgaagtgca gcagcgccac cagtagcagg gcgacgggac
    18721 gctccaggtc cagcaggcgc tccaccggct cgctggccag cagcgcctgt gggtcccgga
    18781 agtcggccgc gaccacgccg gtgttcgcgt tgccttccag taccgcgcgg ctgtgcgcca
    18841 ccgccaccgg gtcgttgtcc gcgtacacca cgcgggcgtc gggcgccgcc gcctgcgcca
    18901 cctcgtgcgc gttgccgaac gtgggtatgc cggagccgat gtcgaggaac tgggtgatgc
    18961 cctcgtccac ggcgtagcgc acggcgcggc gcatgaaggc gcggttggcc tgcatcacct
    19021 tgggcagccc ggggaacacc tcgatcgccc ggcgcgcggc ctcccggtca acctcgaagt
    19081 tgtgggagcc gcccaggtag tagtcgtaga tccgggacac gctcggctga gacaggtcga
    19141 tgccctgcgg ggcccaggag ggacgttcca tcaaagactc ctcatcacgg tgcacgatcg
    19201 tcggcgtatt gacgttcgag ggatgaggct actgacctga ggtgcgtggg agtaaggaaa
    19261 cggagactca atctcccgat actgtcctaa tgttgagggt tatgcccggt tcgtgggggc
    19321 ggaatcctca gccggtgcgc cgacctccgg cctcctgagc gcctgtttcc cgccccggtg
    19381 cgcgggtacc cgccgttcga acaccacggg aggtgagcat ccgtgcccgg acgccaggaa
    19441 ctgccctcga ccctgcgccg ttccccgcag ggcgcgcagc gcacgtgggt caaggcacac
    19501 gactcggccg tcgagactta cggcgagggc gaacgcgcgc accgcgtcgc gttcagcgcc
    19561 ctcaagcaca gctacgagaa ggtaggcgac cactgggagc gcaaggaggg cggccgcagg
    19621 ggcccctccg accccagggc cgcgcggccc cgccagcagg gcgggcgcag cggtcagggc
    19681 gttgacgaga gcgcgagcaa gcggcatctg tacgagatcg cccagcggct cgacatcccc
    19741 ggccgctcag ccatgacgaa gggtgagctg ctgagcgcga tccgcaaggc gaaccgctca
    19801 gtcacgcgca aggcgcggga atagctcagc ccgaccgtcc cacgctccgc cgcgcctctc
    19861 ctctctgtgc cagccagcga ggtctggccg tgcggcgagg ccggaggcga cacgcagccc
    19921 acggccaccc ggctgggtac gctgtgccca gcggccggac tgccgtgcgt cggcagcgcg
    19981 gaccgtctgg ggcggggcct cggccgggta gccgcgcgag gcacgggaca ggccagccgg
    20041 accgccgaac cccctggccc gccgcagctc gcgcactggc gccacgaagt ggcttcttgc
    20101 gccgtccgag ccccgccacg ggagcgaggg gatgttcatg tgtaggttcc cggccggggg
    20161 atcactcgcc gggtatgaac gacaagaacg tcttgccgcc ggaccctgcc gaccgggagc
    20221 cgaagcgctc tgtgggccgc ccgtccggga gcggggtgcc gccgggcgaa acgccgcccg
    20281 ctgagggctc caccctggat gccgggcccg aggagaccta caacccgacc acgggctggg
    20341 cccgtggtcc gctgatcgtg atcgcgctca tcgtcgtcgt cttcgtgggc tacttcgtcg
    20401 cccgcctctt tgcgacctga gccgttcgag ccgtccccgg tgcctccagc gttcccaggc
    20461 cccgggtggt gctcctactc gcggcccttg accgaagtgg cgaactcgcg caggcggccg
    20521 cccgcgcggt gcggacgcaa cggcggcgtg ggcagacccg cgcccgcgcg cagcgcgcgg
    20581 aggaactcgg cgaggatctg ggggccggag cggcgcgggg cccagtccag ctcctcgcgg
    20641 gcccgcgagg tgtccatcaa cggcagccgc aggaacgcgt cgaagaggta cggcgacgcg
    20701 ggtaccgccc gcaggcgcca ggccgcccag agcgcgccgc gcagcggggc cgggggaagc
    20761 cgcaccgggc gggcgcccag cacatccccc agcacccggg cgtcgatcgg cggttcggcg
    20821 gccaggttga acgcgccgga gacgtcccgc agcaccgcgc gggtgaacgc ggtcgccgcg
    20881 tcgtcggtgt gcagcacctg gaaccgcatc ccgggcacgt ccggcagcac cggcaccaca
    20941 ccgggccgca ccagacggtg gggcaggaac ggacccatga acaggcgccg ctgctccatc
    21001 gcggagctct ccttgaacat gaacgcgggc cgcatgcgtg tcacccggat gccggggtgc
    21061 tcgcgttcga aggcgtcgag caggcgctcc acgtacgcct tctcgcgggt gtacgcggcc
    21121 tggggccagc cgtgcgtggg ccaggactcg tccgcccgct cggccttgcc ggggtccggc
    21181 cagggcgagt acgcgcccac cgacgaggag tacaccagcg ccgggacgcc cgccgtggcc
    21241 atcgcgcgca gcacccgctc ggtgccgacg acgttggtgc gccaggtggt ggcgggggag
    21301 tgggtgggct ggatcagcca ggcgaggtgg atgacggcgt ccgcgccctg gagcagcccg
    21361 gtcagcccgg cctcggcgtc ctccgtaccg aggtccacgc tcgcccaccg caccttgctc
    21421 ggcgtccact gcggaacgcg ccgcgccagg cccagcaccg aggccacacc cggttcggcc
    21481 gcgagggcgc cgagcacgct cgtgccgacg ttgccgcttg cgccggtcac caccacccgc
    21541 agtccgtcgc tgtcgctcac cgggaccccc tttcgttcac cgtcaccggc cgcacgtccg
    21601 gaagacgcgg cgagtacccc gcaccgggtg gccggaaacg gcgcggcccg gccggatgaa
    21661 ctctgttttc cggtacgggc gcgcgggtac acggcgcgcc atgcagcagc ctgacccctc
    21721 ccgcgacccg gacgccgagc gtgcggggct gctcggccgc gtctcacccc gcaccgggag
    21781 ggaaccggcg cgcgcccaca gcgccctgcg gctgcgctgg ctgctgagcc tgctgttcac
    21841 accgctgttc atcgccgggg cggtgctgtt ctgggcctgg tcggcggcgt ccggaccgat
    21901 ggacgtgccc accgacacct ccctgcgggt gcttgccggg atcttcacct tcctggccgt
    21961 gttcgcgttc gcggacctgc tggtggtaca aggccgcctg caccgcgcca ggcagcgcgc
    22021 ccgccgccgc gccgggcact gacgcgccgc accctgaacc ccgggcctgt ccgtccggtc
    22081 cgcccaccac gccccgcccc gccgggagtc ttcaccccgg gtgcacaacc gccgtgcccg
    22141 ccgaccgcgc tgcccgcccc gccgcgctgg ctgcccgtcg tccctgagcg atgaggcgtg
    22201 aagccaccca gcccgggtac gcggcaggcc gtgccacgca acaccagcga ctcaggaggt
    22261 gccatgtcgc acatcgagga atccatcgag ctcgacgttc ccgtgtccac ggcctacaac
    22321 cagtggacac agttcacgga cttcccccac ttcatggaag gagtcgagcg cgtcgaccag
    22381 gtgaccgaca cctccaccca ctgggtgacg aagatcgccg gggtggagcg ggagttcgac
    22441 gcggacatca ctgagcagat ccccgacgag cggatcgcgt ggaccagccg caacggtccc
    22501 aagcaggccg gagtcgtgac cttccaccac ctgacgccgg gccgttccaa ggtgatgctg
    22561 caactggagt acgcaccgga gtacttcacc gaggcggtcg gcgacgcgct cggcttggtc
    22621 aagcgcaagg cagccggtga cctggagcgg ttcaagaagt tcatcgagag ccggggcacg
    22681 gagaccggcg cctggcgcgg cgaggtctga tccacaccgg gccgcccccg gcgaacccgg
    22741 ccacgcgcag cagcccccgg caccaggacg tgccgggggc tgcgcgctgc cggaccgccg
    22801 cggccacggg gagccggggg ccacgcctgc cccgcggtcg gcgcgcgtcc ggagggcacg
    22861 gtgttattcc gccctggtca ggggtacgcg agcggcggcg aaccgtgatc gtgcaggaga
    22921 cagaaggagg ccgtcatgac ggaaccgaac ccggagagca acgaccccgg caggaacccc
    22981 gaggacgagg gcatccccga cctgcaggac gggtggccca aggcgcagca ggccgaggac
    23041 ccgcagcaga tgccggttcc cggcgaccgc ccggtggcgg ccgaaagcca cggcaccacg
    23101 cccagtgagc agcgcgaggg cgagtcgctg gacgcccggc tcgcgcagga ggaaccggac
    23161 gtggacgagg agaccggcgc ggccggtacg ccggacccgg aggcgggcca gatcagcgac
    23221 gagcggctgc ccggcacccc gtccggtgac cacctcgtcg gccacgagtc cccagcggcc
    23281 gggctgcccg ccgaggagcg cgccctgcac atcgagagca tggacgaggc cgacgcacca
    23341 ccctcggacc cggaggagaa tccggcggac gagcagcggt gagcgcccgc cgggggcacc
    23401 ggcgtcctca gatggtcacg ccgtttgccc gcaggtaggc gagcgggttg atgtccgagc
    23461 cgtagccggg ccccgtgcgg atctcgaagt gcaggtgcgg accggtggaa ttcccggtgt
    23521 tgccggagcg cccgagcgtt ttcccggcgc ccacctgctg cccggcccgc acggagatcg
    23581 ccgagaggtg ggcgtactgg ctgtagcgcc cgtcgtggtg ccggagcacc acctggtaac
    23641 cgtaggaacc cgcccagccc gccgagacga cggtggcacc ggtaacggcc ctgacggagg
    23701 tgcccgtcgg cagggggaag tccacgccgg tgtggtagcc ggaggaccac gagctgccgc
    23761 tcacccggta ggcggtgccg gcggaggcgc cgggcacggg cgcggagaac gccggggtgg
    23821 aggggcgctg ggcggcccgg ttccccgccg aggcggaccg ctcgggcttc ggttcgggct
    23881 tcgcctcctg cttcggttcg ggcttcggtt cgggtttcgg ctcggggttc gccttggatt
    23941 ctggggccgg tggcgtcgcc tcggactgct tgggctgctc gccgctgtgg gccttctccg
    24001 ccttctccgc cttctccgcc gtctcccgcg gtgccttcgg acgcgtgcgc tccggtgcct
    24061 tctgcggcgt ccgggcgggt ggaccggcag cggtcaggcg cagctgctga ccggggaaga
    24121 tcaggtgcgg gtcatcgccg atcgtggcgc ggttgcgctc gtacagcgcg ggccagccgc
    24181 cggtgacgtc gtgttcctgt gcgatcgtgg acaggctctc gccggggacg acgtcatggg
    24241 tggcgttgcc gcgctggtgc tcctgcccgt gggggccgtt gtccgcggcg ggccgctgcc
    24301 gtggtacggc ggccgggcgg gcgacggtgc gggtcgcgga gtcgcgggcg gcgcgcggct
    24361 cggcggcgtc gcgggtgaga ccggcgcggg gaccgcactg gggccaggcc ccgggcccct
    24421 gtccggcaag aaccttctcg gccaccgcta tctgttcggc cggtgacgcc tggtca
//
