LOCUS       NZ_CP079114            26574 bp    DNA     linear   CON 06-SEP-2024
DEFINITION  Streptomyces sp. WY228 chromosome.
ACCESSION   NZ_CP079114
VERSION     NZ_CP079114.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. WY228
  ORGANISM  Streptomyces sp. WY228
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8286721)
  AUTHORS   Qin,S.
  TITLE     Volatile organic compounds produced by endophyte Streptomyces sp.
            WY228 mediate plant growth and salt stress tolerance by activating
            hormonal signaling and anthocyanin biosynthesis,
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 8286721)
  AUTHORS   Qin,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUL-2021) Key lab of biotechnology of medicinal
            plants, Jiangsu Normal University, No. 101 Shanghai Road, Xuzhou
            221116, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Canu v. 1.5
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 100.0x
            Sequencing Technology             :: Oxford Nanopore
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_019287315.1-RS_2024_09_06
            Annotation Date                   :: 09/06/2024 06:02:41
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,303
            CDSs (total)                      :: 7,213
            Genes (coding)                    :: 7,059
            CDSs (with protein)               :: 7,059
            Genes (RNA)                       :: 90
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 155
            CDSs (without protein)            :: 154
            Pseudo Genes (ambiguous residues) :: 0 of 155
            Pseudo Genes (frameshifted)       :: 83 of 155
            Pseudo Genes (incomplete)         :: 99 of 155
            Pseudo Genes (internal stop)      :: 10 of 155
            Pseudo Genes (multiple problems)  :: 36 of 155
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 03:35:29
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 7360680
            Orig. end                         :: 7387254
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP079114.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..26574
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="29"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..26574
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..26574
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:16574](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..16574
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    complement(9..27)
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: weak, score: 21.29"
                     /tool="antismash"
     misc_feature    146..161
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.04"
                     /tool="antismash"
     gene            complement(192..1133)
                     /locus_tag="KV381_RS32240"
                     /old_locus_tag="KV381_32240"
     CDS             complement(192..1133)
                     /GO_function="GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014049646.1"
                     /locus_tag="KV381_RS32240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_32240"
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="WP_103536887.1"
                     /transl_table=11
                     /translation="MGAGHDHGHTHGGPPATGTAAAAYRGRLRVALAITLSVMVMEIVG
                     GVLSDSLALIADAAHMATDALGLGMALLAIHFANRPAGPNRTFGFARAEILAALANCLL
                     LLGVGGYLVFEAVERFITPAETKGGLAIAFAAVGLVANIVSLSLLMRGQKESLNVRGAY
                     LEVMADTLGSIAVIVSAGVIMATGWQAADPIASLAIGLMIVPRTVKLLRETLNVLLEAA
                     PKGVDMAEVRAHITALPGVLDVHDLHAWTITSGMPVLSAHVVVRQEMLDSIGHEKVLHE
                     LQGCLGDHFDVEHCTFQLEPSGHAEHEAHLCH"
     misc_feature    1228..1242
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.72"
                     /tool="antismash"
     gene            complement(1314..2291)
                     /gene="galE"
                     /locus_tag="KV381_RS32245"
                     /old_locus_tag="KV381_32245"
     CDS             complement(1314..2291)
                     /EC_number="5.1.3.2"
                     /GO_function="GO:0003978 - UDP-glucose 4-epimerase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006012 - galactose metabolic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: NAD_binding_4 (64-206). E-value:
                     1.2e-09. Score: 29.6. Matches aSDomain:
                     nrpspksdomains_KV381_RS32245_NAD_binding_4.1"
                     /codon_start=1
                     /gene="galE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010: NAD-dependent epimerase/dehydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006128924.1"
                     /locus_tag="KV381_RS32245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_32245"
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="WP_103536886.1"
                     /sec_met_domain="RmlD_sub_bind (E-value: 2.7e-18, bitscore:
                     64.8, seeds: 37, tool: rule-based-clusters)"
                     /sec_met_domain="Polysacc_synt_2 (E-value: 1.1e-11,
                     bitscore: 43.1, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTWLITGGAGYIGAHVARAMVAAGERVVVLDDRSSGIVDRLPEDV
                     TLVEGSASDRALLDRVLAGHTVSGVVHLAAKKQVGESVEKPLLYYRENVAGLGVLLEAV
                     VAAGVRRFLFSSSAAVYGVPDVELITEETPCLPINPYGETKLTGEWLVRATGKAHGIST
                     ACLRYFNVAGSAAPELADTGVFNIVPMMFERLTRGEAPRIFGDDYPTPDGTCVRDYIHV
                     ADLAEAHLAVARRLDGADAVDLTLNVGRGEGVSVRELAEVIGEVTGHGLEPVVEPRRAG
                     DAPKAVASAARITEELGWTARRSVREMVESAWEGWQLRHPEARP"
     aSDomain        complement(1674..2099)
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_KV381_RS32245_NAD_binding_4.1"
                     /evalue="1.20E-09"
                     /label="KV381_RS32245_NAD_binding_4.1"
                     /locus_tag="KV381_RS32245"
                     /protein_end="206"
                     /protein_start="64"
                     /score="29.6"
                     /tool="antismash"
                     /translation="HTVSGVVHLAAKKQVGESVEKPLLYYRENVAGLGVLLEAVVAAGV
                     RRFLFSSSAAVYGVPDVELITEETPCLPINPYGETKLTGEWLVRATGKAHGISTACLRY
                     FNVAGSAAPELADTGVFNIVPMMFERLTRGEAPRIFGD"
     CDS_motif       complement(1833..1979)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_KV381_RS32245_0002"
                     /evalue="3.90E+01"
                     /label="PKSI-KR_m1"
                     /locus_tag="KV381_RS32245"
                     /protein_end="153"
                     /protein_start="104"
                     /score="-2.9"
                     /tool="antismash"
                     /translation="VAAGVRRFLFSSSAAVYGVPDVELITEETPCLPINPYGETKLTGE
                     WLVR"
     CDS_motif       complement(2202..2288)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_KV381_RS32245_0001"
                     /evalue="9.40E-09"
                     /label="PKSI-KR_m1"
                     /locus_tag="KV381_RS32245"
                     /protein_end="30"
                     /protein_start="1"
                     /score="27.9"
                     /tool="antismash"
                     /translation="TWLITGGAGYIGAHVARAMVAAGERVVVL"
     misc_feature    complement(2355..2369)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: medium, score: 19.02"
                     /tool="antismash"
     misc_feature    2355..2370
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 17.59"
                     /tool="antismash"
     misc_feature    complement(2366..2381)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 22.92"
                     /tool="antismash"
     gene            2609..4363
                     /locus_tag="KV381_RS32250"
                     /old_locus_tag="KV381_32250"
     CDS             2609..4363
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018955402.1"
                     /locus_tag="KV381_RS32250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_32250"
                     /product="DUF5941 domain-containing protein"
                     /protein_id="WP_218786910.1"
                     /transl_table=11
                     /translation="MQTAVDAGDAAALLAAVPAGRRVALVDPRFVGHVHALRLGLTDPR
                     FAVATVPGALTARPEARGALLSALRRTTAAVGAGAPVVEPDTDPAPEDRTVPGRIAVAL
                     EADGTAVQRPALGSLVAAVPTDPEQRAAAEAGLASVDDEAVRLRSAVKAHDGFFTTFCI
                     SPYSRYIARWCARRNLTPNQVTTASLITALIAAGAAATGTRGGYVAAGILLMVSFVLDC
                     TDGQLARYSLQYSTMGAWLDATFDRAKEYAYYAGLAIGAVRGGDDVWVLALGAMVLQAC
                     RHVVDFSFNEANHDAVANTSPTAALSGKLDSVGWTVWARRMIVLPIGERWAMIAVLTAL
                     TTPRIVFYALLIGCALAACYTTAGRLLRSLTRKARRTDRAAQALADLADSGPLAQGVAA
                     VAPGLRGAFTAPAVALLGTLVMIGGALFLPYGSWLTVAAAAVYVVLSGLAVARPLKGAL
                     DWLVPPFFRAAEYVTILVLAARSDVPHAVPAAFGLVSAVAYHHYDTVYRIRGGTGAPPQ
                     WLVRTIGGHEGRTALVAVLAAVLTHASGFTTALTALAVAVALVVLVESIRFWVSSSAPA
                     VHDEGELA"
     gene            4360..5097
                     /locus_tag="KV381_RS32255"
                     /old_locus_tag="KV381_32255"
     CDS             4360..5097
                     /GO_function="GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064: glucose-1-phosphate
                     adenylyl/thymidylyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018955403.1"
                     /locus_tag="KV381_RS32255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_32255"
                     /product="sugar phosphate nucleotidyltransferase"
                     /protein_id="WP_030076405.1"
                     /sec_met_domain="NTP_transf_3 (E-value: 1.2e-11, bitscore:
                     43.9, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIGLVLAAGAGRRLRPYTDTLPKALVPVDGDKTVLDLTLANFAEV
                     GLTEVAIVVGYRKEAVYARKAELEATYGLTLTLIDNDKAEEWNNAYSLWCARDVIKRGV
                     ILANGDTVHPVSVEKTLLDARGKGQKIILALDTEKSLADEEMKVITAEGKGVQRITKLM
                     DPATATGEYIGVTLIEAEAAEELADALKTTFERDPDLYYEDGYQELVNRGFTVDVAPIG
                     TVTWVEIDNHDDLKKGREIACQY"
     gene            5085..6146
                     /locus_tag="KV381_RS32260"
                     /old_locus_tag="KV381_32260"
     CDS             5085..6146
                     /GO_function="GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fe-ADH"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DHQ_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1181: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007452391.1"
                     /locus_tag="KV381_RS32260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_32260"
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="WP_030623265.1"
                     /sec_met_domain="Fe-ADH (E-value: 1.7e-18, bitscore: 65.2,
                     seeds: 218, tool: rule-based-clusters)"
                     /sec_met_domain="DHQ_synthase (E-value: 3.7e-09, bitscore:
                     34.8, seeds: 76, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPVLTRLIPSPVVVDIRRGAMDDLAGLLADQRISTSGKLAIAISD
                     GSGRALRERLAPVLPGADWYPVSDGTIDSAVKLADGIKGNRYDAVVGLGGGKIIDVAKY
                     AAARVGLPLVAVATNLSHDGLCSPVATLDNDNGRGSYGVPTPIAVVIDLDVIREAPARY
                     VRSGIGDAISNISCVADWELAHEVNGEEIDGLAAAMARQAGEAVLRHPGGVGDDAFLKV
                     LAEGLVLTGISMSVAGDSRPASGACHEINHAFDLLYPQRAASHGEQVGLGACFAMHLRG
                     ARQESLLMASILRRHGLPVLPEEIGFSVDEFVKAVDYAPQTRPGRFTVLEHLNLSTDQI
                     RDAYADYASTISS"
     gene            6124..6903
                     /locus_tag="KV381_RS32265"
                     /old_locus_tag="KV381_32265"
     CDS             6124..6903
                     /EC_number="2.7.8.-"
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_function="GO:0000287 - magnesium ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA]"
                     /GO_process="GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014049651.1"
                     /locus_tag="KV381_RS32265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_32265"
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="WP_078611032.1"
                     /transl_table=11
                     /translation="MPRPSVAELRPVVHPPGVKDRRSGEHWAGRMYMREVSLRVDRYLV
                     NTRVTPNQVTYVMTLAGALAAPALLVPGVWGAVLGVVMVQLYLLFDCVDGELARWKKQY
                     SLSGVYLDRVAAYLCDAAVLVGLGLRAADIWGEGRIDWLWAFLGTLAALGAILIKAETD
                     LVGVARHQGGLPPVKEAASEPRSSGVALARKAAAALKFHRLILGIEASLVILVVAVVDA
                     IGGDLFYTRLTVAVMAGIALLQTLLHLVSVLASSRLK"
     gene            6912..7784
                     /locus_tag="KV381_RS32270"
                     /old_locus_tag="KV381_32270"
     CDS             6912..7784
                     /EC_number="2.4.-.-"
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018513265.1"
                     /locus_tag="KV381_RS32270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_32270"
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="WP_218787344.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 2.4e-10,
                     bitscore: 39.2, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKLGAVIITMGNRPDELRALLDSVTAQHGDRIEVVVVGNGAPVPD
                     VPAGVRTVELPENLGIPGGRNVGIEAFGPCGADVDALLFLDDDGLLPNRNTAELCRQAF
                     EADPKLGIVTFRIADPETGATQRRHVPRLRAADPMRSSRVTTFLGGANALRTKVIAEVG
                     PLPEDFFYAHEETDLAWRALDAGWMIDYRADMVLNHPTTAPSRHAVYHRMVARNRVWLA
                     RRNLPAPLVPLYLGVWLLLTLVRRPSPPALKAWFGGFREGWSTPCGPRRPMKWRTVWRL
                     TRLGRPPVI"
     gene            7886..8815
                     /locus_tag="KV381_RS32275"
                     /old_locus_tag="KV381_32275"
     CDS             7886..8815
                     /GO_component="GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003964854.1"
                     /locus_tag="KV381_RS32275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_32275"
                     /product="ABC transporter permease"
                     /protein_id="WP_030076413.1"
                     /transl_table=11
                     /translation="MSDTTHDGGVALGTPPSADEGLGAAQLAAKYGLTVSGARPGLFAY
                     MRQLWGRRHFILAFSRAKLTAQYSQAKLGQLWQVVTPLLNACVYYLIFGLILGTREGIP
                     HDVFVPFLVTGVFVFTFTQSSVMAGVRAISGNLGLVRALHFPRASLPISFSLQQLQQLL
                     FSMIVLVAVAVIFGSYPSLSWLLVIPALILQFFFNTGLALVMARLGSKTPDLAQLMPFV
                     MRTWMYASGVMFSIPVMLKDKPAWIADVLQYNPAAVYMDLVRFALIDGYGSENLPDHVW
                     AVGLGWAVLLGVVGFVYFWKAEERYGRG"
     gene            8808..9593
                     /locus_tag="KV381_RS32280"
                     /old_locus_tag="KV381_32280"
     CDS             8808..9593
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003964853.1"
                     /locus_tag="KV381_RS32280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_32280"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_030076415.1"
                     /transl_table=11
                     /translation="MADDNAQGRIPTVIADDVHIVYRVNGTGGGRGSATAALSRMMRRG
                     KGEPRGVRKVHAVRGVSFTAYRGEAIGLIGTNGSGKSTLLRAIAGLLPTESGQVYTDGQ
                     PSLLGVNAALMSDLTGERNVVLGGLAMGMTQAEVRSRYQEIVDFSGINEKGDFITLPMR
                     TYSSGMAARLRFSIAAAKNHDVLMIDEALATGDRKFRVRSEERIRELRKEAGTVFLVSH
                     NNKSIRDTCDRALWLEKGELLMDGPTEEVLKAYERETGK"
     gene            10001..10912
                     /gene="hpnC"
                     /locus_tag="KV381_RS32285"
                     /old_locus_tag="KV381_32285"
     CDS             10001..10912
                     /EC_number="2.5.1.21"
                     /GO_function="GO:0004311 - farnesyltranstransferase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018955408.1"
                     /locus_tag="KV381_RS32285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_32285"
                     /product="squalene synthase HpnC"
                     /protein_id="WP_218786911.1"
                     /sec_met_domain="PT_phytoene_like (E-value: 4.6e-40,
                     bitscore: 136.4, seeds: 61, tool: rule-based-clusters)"
                     /sec_met_domain="phytoene_synt (E-value: 1.6e-35, bitscore:
                     121.4, seeds: 8, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSPPEARIGDATLGKAADENFPVAPFFLPRAWRDDLMAVYGFAR
                     LVDDIGDGDLAPGGADARHLGLEPEQSDDRLAMLDAFEADLHRVFATTGDEPRHPLLRN
                     LRPTVRRRALTPEPFLGLIEANRQDQKIRRYGTYAELAAYCELSANPVGRLVLALTGTT
                     SPERVRRSDAVCTALQIVEHLQDVAEDLARDRIYLPAEDMERFRVTETDLAAPTAGASV
                     RALIAYEAQRASDLLDEGPPLVGSVDGRLKLLLAGFVGGGRSALTAISAAGFDVLPGPP
                     KPTKPSLLREVGIVLRRARGER"
     gene            10942..11862
                     /gene="hpnD"
                     /locus_tag="KV381_RS32290"
                     /old_locus_tag="KV381_32290"
     CDS             10942..11862
                     /EC_number="2.5.1.103"
                     /GO_function="GO:0016767 - geranylgeranyl-diphosphate
                     geranylgeranyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0016117 - carotenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnD"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018492033.1"
                     /locus_tag="KV381_RS32290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_32290"
                     /product="presqualene diphosphate synthase HpnD"
                     /protein_id="WP_179889538.1"
                     /sec_met_domain="phytoene_synt (E-value: 6.1e-58, bitscore:
                     194.9, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 1.6e-70,
                     bitscore: 236.4, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSPPVQAAYSYCEAVTGQQARNFAYGIRLLPYEKRQAMSALYAFS
                     RRVDDIGDGELDPETKRTRLESTRELLERIRKDAVDEDDTDPVAVALADAARRFPLPLG
                     GLDELIDGVLMDVRGATYETWDDLKAYCRCVAGAIGRLSLGVFGTAPGARGAERAAEYA
                     DTLGLALQLTNILRDVREDAGNGRTYLPADDLAKFGCSAGFHRTTPPPGSDFAGLIHFE
                     VRRARALFAEGYRLLPMLDRRSGACVAAMAGIYRRLLDRIERDPEAVLRGRVSLPGHEK
                     AYVAVRGLSGLDARHISRLTARGRS"
     misc_feature    complement(10955..10973)
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 18.72"
                     /tool="antismash"
     gene            11981..13366
                     /gene="hpnE"
                     /locus_tag="KV381_RS32295"
                     /old_locus_tag="KV381_32295"
     CDS             11981..13366
                     /EC_number="1.17.8.1"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012378207.1"
                     /locus_tag="KV381_RS32295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_32295"
                     /product="hydroxysqualene dehydroxylase HpnE"
                     /protein_id="WP_218786912.1"
                     /sec_met_domain="DAO (E-value: 2e-07, bitscore: 29.6,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDETPRPVAVVVGGGLAGVTAALRLADAGLDVTLLEGRPRLGGL
                     AFSFQRGDLTVDNGQHVYLRCCTGYRWFLDRIDASHLAPLQDRLDVPVLDVGRAAGPRL
                     GRIRRTGLPVPLHLAGGLAAYPHLSLAEKASVGRAALALGRLDPADPELDRVDFATWLR
                     RNGQSERTIEALWDLVGVATLNATAPNASMALAAKVFKTGLLSEPGAADIGWAAVPLGE
                     LHDTLARKALDTAGVRTELRAKAGSLTRTEDGRWSVETAGERITADTVVLAVPQTETHD
                     LLPAGALDEPELLLDIDNAPILNVHVIYDRKVLRRPFFAAIGSPVQWVFDRTHASGLTG
                     PGQYLAVSQSAAQDEIDLPVAELRSRYLPELERLLPAARGAGIRDFFVTRERTATFAPA
                     PGVGRLRPGPRTRLPGLQLAGAWTATGWPATMEGAVRSGAGAADAALQDLGRPLGHPLQ
                     EAA"
     gene            13363..14466
                     /locus_tag="KV381_RS32300"
                     /old_locus_tag="KV381_32300"
     CDS             13363..14466
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003964849.1"
                     /locus_tag="KV381_RS32300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_32300"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_030623252.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 9.1e-60, bitscore:
                     200.9, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSTTGTRGESVTPANPAFDTVADTADVTALLERGRALSAPVLRA
                     AVDRLAPPMDTVAAYHFGWIDAEGRPSDGDGGKAVRPALALLSAEAAGAPAEAGIPGAV
                     AVELVHNFSLLHDDLMDGDEQRRHRDTVWKVHGPAQAILVGDALFALAYDLLLELGTVE
                     AGRAARRLTTATRKLIDGQAQDISYEHRERVTVEECLEMEGNKTGALLACAVSIGAVLG
                     GADDRTADTLEAYGYHLGLAFQAVDDLLGIWGDPESTGKQTWSDLRQRKKSLPVVAALA
                     AGGEASERLGELLAADAKSNDFDSFSEEEFAARAALIEEAGGREWTAQEARRQHAVAIE
                     ALHAVDMPHRVREQLTELADFVVVRKR"
     misc_feature    14474..14490
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 21.23"
                     /tool="antismash"
     gene            14574..16574
                     /gene="shc"
                     /locus_tag="KV381_RS32305"
                     /old_locus_tag="KV381_32305"
     CDS             14574..16574
                     /EC_number="5.4.99.17"
                     /GO_function="GO:0016866 - intramolecular transferase
                     activity [Evidence IEA]"
                     /GO_function="GO:0051007 - squalene-hopene cyclase activity
                     [Evidence IEA]"
                     /GO_process="GO:0019746 - hopanoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="shc"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T2TS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003964848.1"
                     /locus_tag="KV381_RS32305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_32305"
                     /product="squalene--hopene cyclase"
                     /protein_id="WP_098026227.1"
                     /sec_met_domain="T2TS (E-value: 1.9e-146, bitscore: 487.5,
                     seeds: 58, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTATTDGSTGAANLSGAPADDPTDTTTAADDVTAAARRAAERSVE
                     HLLGRQDEQGWWKGDLATNVTMDAEDLLLRQFLGIQDAETTRAAALFIRGEQLGDGTWN
                     TFYGGPGDLSATIEAYVALRLAGDRPDEPHMARASGWIREQGGIAAARVFTRIWLALFG
                     WWKWDDLPELPPELMFFPKWVPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFALDELH
                     TDPDHPNPARKLAPPASWDGLFQRLDKGLHLYHKVAPRPLRRIAMNVAARWIIERQEND
                     GCWGGIQPPAVYSIIALHLLGYDLDHPVMKAGLASLDRFAVRREDGARMVEACQSPVWD
                     TCLATIALADAGLRPDHPALVKAADWMLAEEITRPGDWAVRKPELAPGGWAFEFHNDNY
                     PDIDDTAEVVLALRRVRHPDPARMQAAIDRGVRWNLGMQSRNGAWGAFDADNTSPFPNR
                     LPFCDFGEVIDPPSADVTGHVVEMLAVEGLANHPRTREGIEWLLAEQEACGAWFGRWGV
                     NYVYGTGSVVPALIAAGLPAGHPAIRRAVGWLESVQNDDGGWGEDLRSYQEEKWIGHGE
                     STASQTAWALLALLAAGRRDTASVARGVTWLTEAQQADGSWDEPYFTGTGFPWDFSINY
                     HLYRQVFPLTALGRYVYGDPFADRADAVEGA"
     gene            16574..17221
                     /locus_tag="KV381_RS32310"
                     /old_locus_tag="KV381_32310"
     CDS             16574..17221
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003964847.1"
                     /locus_tag="KV381_RS32310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_32310"
                     /product="1-hydroxy-2-methyl-2-butenyl 4-diphosphate
                     reductase"
                     /protein_id="WP_086777576.1"
                     /transl_table=11
                     /translation="MDDPRGPGSPVPPLLVACALGIEQVALRSGRGAPGPVRVLRTGMG
                     PRAAETAVARLLGPDGVPDAAVIASGFCAGLLPGMHPGDLVVAEETRDVDGTTPCTGTG
                     VLVAALARAVPGRTVHTGPLTGSDHVVRGSERAALRAGGAIAVDMESAATLRTALCHGP
                     RPVAAVRVVVDAPEHELVRIGTVRGGISAFRVLRAVLPAFYEWHRSLLLPRR"
     misc_feature    17201..17203
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            17227..18246
                     /gene="hpnH"
                     /locus_tag="KV381_RS32315"
                     /old_locus_tag="KV381_32315"
     CDS             17227..18246
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnH"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) QueE"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006128938.1"
                     /locus_tag="KV381_RS32315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_32315"
                     /product="adenosyl-hopene transferase HpnH"
                     /protein_id="WP_098026228.1"
                     /sec_met_domain="PF04055 (E-value: 3.1e-16, bitscore: 58.9,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="QueE (E-value: 2.4e-08, bitscore: 32.5,
                     seeds: 32, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAMPLRQTIKVATYLFEQKLRKREKFPLIVELEPLFACNLACEGC
                     GKIQHPAGVLKQRMPVAQAVGAVLESGAPMVSIAGGEPLMHPQIDEIVRQLVARKKYVF
                     LCTNAMLMRKKLEKFTPSPYFAFAVHIDGLRERHDESVAKEGVFDEAVAAMKEAKARGF
                     RVTTNSTFFNTDTPQTIIEVLNYLNDDLKVDEMMISPAYAYEKAPDQEHFLGVDQTREL
                     FKKAFAGGNRARWRLNHSPLFLDFLEGKADFPCTAWAIPNYSLFGWQRPCYLMSDGYVP
                     TYRQLIEETDWDKYGRGKDPRCANCMAHCGYEPTAVLATMGSLKESLRAARETVTSNR"
     gene            18338..19735
                     /locus_tag="KV381_RS32320"
                     /old_locus_tag="KV381_32320"
     CDS             18338..19735
                     /NRPS_PKS="Domain: Aminotran_3 (45-367). E-value: 2e-90.
                     Score: 295.2. Matches aSDomain:
                     nrpspksdomains_KV381_RS32320_Aminotran_3.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1013: aminotransferase class-III"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018492039.1"
                     /locus_tag="KV381_RS32320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_32320"
                     /product="aspartate aminotransferase family protein"
                     /protein_id="WP_218786913.1"
                     /sec_met_domain="Aminotran_3 (E-value: 6.5e-89, bitscore:
                     297.1, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDGGSQGFDLARLLAERGSERYELHARHLNHQLPRMLHTIGFDK
                     VYERAEGAYFWDAEGDDYLDMLAGFGVMGLGRHHPVVRQALHDVLDAQLADLTRFDCQP
                     LPGLLAEKLLTHSPHLDRVFFGNSGTEAVETALKFARYATGRPRILYCDHAFHGLTTGS
                     LSVNGESGFRDGFAPLLPDTAVPLGDLDALRRELKRGDVAALVVEPIQGKGVHAAPPGY
                     LRQAQELLHRHKALLIADEVQTGLGRTGDFYAYQHEEGVEPDLVCVAKALSGGYVPVGA
                     TLGKDWIFRKVYSSMDRVLVHSASFGSNAQAMAAGLAVLTVMEDEETVANARRTGDLLR
                     ERLAALVDRYELLHEVRGRGLMIGIEFGRPSSLKLRSRWTMLQAARKGLFAQMVVVPLL
                     QKHRILTQVSGDHLEVIKLIPPLVIGDAEVDRFVAAFTSVMDDAHSGGGLMWDFGRTLV
                     KQAVANR"
     aSDomain        18473..19438
                     /aSDomain="Aminotran_3"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_KV381_RS32320_Aminotran_3.1"
                     /evalue="2.00E-90"
                     /label="KV381_RS32320_Aminotran_3.1"
                     /locus_tag="KV381_RS32320"
                     /protein_end="367"
                     /protein_start="45"
                     /score="295.2"
                     /tool="antismash"
                     /translation="VYERAEGAYFWDAEGDDYLDMLAGFGVMGLGRHHPVVRQALHDVL
                     DAQLADLTRFDCQPLPGLLAEKLLTHSPHLDRVFFGNSGTEAVETALKFARYATGRPRI
                     LYCDHAFHGLTTGSLSVNGESGFRDGFAPLLPDTAVPLGDLDALRRELKRGDVAALVVE
                     PIQGKGVHAAPPGYLRQAQELLHRHKALLIADEVQTGLGRTGDFYAYQHEEGVEPDLVC
                     VAKALSGGYVPVGATLGKDWIFRKVYSSMDRVLVHSASFGSNAQAMAAGLAVLTVMEDE
                     ETVANARRTGDLLRERLAALVDRYELLHEVRGRGLMIGIEF"
     gene            19802..20410
                     /locus_tag="KV381_RS32325"
                     /old_locus_tag="KV381_32325"
     CDS             19802..20410
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1148: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018955416.1"
                     /locus_tag="KV381_RS32325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_32325"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_030623236.1"
                     /transl_table=11
                     /translation="MNPPDEGVPDELPGVAPRLRDLRRSRGLTLETAARRAGLSPAHLS
                     RLETGRRQPSLPMLLGLARIYGTTVSELLGEQPPERDAIVRGGGFEGAEADGWMYRQAG
                     GSGRAMQALRVRVPYGAQGDLVRVHPGEEWLYVMEGRLRVGLGDTVHDLEPGDSAHFDS
                     LTPHRIAAVDRGGAELLFVHTLLQSPAAELCLGNALHAR"
     gene            20475..20648
                     /locus_tag="KV381_RS32330"
                     /old_locus_tag="KV381_32330"
     CDS             20475..20648
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018955417.1"
                     /locus_tag="KV381_RS32330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_32330"
                     /product="DUF6126 family protein"
                     /protein_id="WP_167396290.1"
                     /transl_table=11
                     /translation="MSDSEHYDPLGPGRRVNEDPQEKRMPRGVVIRLFAYLVAGHVIAG
                     FLYLLFVVAGSK"
     gene            complement(20668..21480)
                     /locus_tag="KV381_RS32335"
                     /old_locus_tag="KV381_32335"
     CDS             complement(20668..21480)
                     /EC_number="3.1.3.48"
                     /GO_function="GO:0004721 - phosphoprotein phosphatase
                     activity [Evidence IEA]"
                     /GO_function="GO:0004725 - protein tyrosine phosphatase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006345417.1"
                     /locus_tag="KV381_RS32335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_32335"
                     /product="tyrosine-protein phosphatase"
                     /protein_id="WP_030623233.1"
                     /transl_table=11
                     /translation="MTQQVPQVPPTETVLTGVRNFRDVGGLPTTDGRRTAFGRLYRSGH
                     LAHATAEDAAFLGGLGLHTVFDFRHSADHRLDGYDIELPGVRNVSIPLSDPADGAEFWR
                     LVSDGNIEQLRSVLADGKGVDRMIRMYRATIEDRTVEHSRVLHALAEDSVPALMHCAAG
                     KDRAGLSIAVALLAVGVEVEAIEEDYLKSNDLHRRYNVKRSDASEAGMSPEVLELLDPL
                     FGARPAYLAAAFATIEENWGTTDRYLTEGLKISSGTRERLRERLLDQD"
     misc_feature    21551..21565
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 16.81"
                     /tool="antismash"
     misc_feature    21655..21669
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.37"
                     /tool="antismash"
     misc_feature    complement(21811..21827)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 16.82"
                     /tool="antismash"
     misc_feature    complement(21896..21910)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 19.09"
                     /tool="antismash"
     regulatory      21924..22082
                     /bound_moiety="cyclic di-AMP"
                     /db_xref="RFAM:RF00379"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00379"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cyclic di-AMP (ydaO/yuaA leader) riboswitch senses
                     the signaling molecule cyclic di-AMP; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /regulatory_class="riboswitch"
     gene            22088..23044
                     /locus_tag="KV381_RS32340"
                     /old_locus_tag="KV381_32340"
     CDS             22088..23044
                     /EC_number="3.4.-.-"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006128943.1"
                     /locus_tag="KV381_RS32340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_32340"
                     /product="LysM peptidoglycan-binding domain-containing M23
                     family metallopeptidase"
                     /protein_id="WP_218786914.1"
                     /transl_table=11
                     /translation="MPAKGKHRRPKSGPISRGVLAAGTGGAALALPLIGAGIASAADRA
                     APAAKPAAASVAAAHTAPSAAPAASKAAPKAYSVVSGDYLSKIAAEHQLKGGWQKLYQD
                     NRSTVGENPGLIHPGMKLTLGAKGSAPAEKSAAPEAAPKKAAPAPKAAPKEAPKGDTIS
                     ADDSEGSGASAQTGSSEATGSGWSAPLANANVTTQYRASGASWSSGYHTGSDFQAASGT
                     PVLAIGPGTVVSAGNSGSYGNEVVIQHEDGMYSQYAHQSSLNVSVGQTVTGGQQIGLSG
                     STGNSTGPHLHFEVRTGPSYGSDVDPIAYLRQHGVSV"
     misc_feature    23123..23138
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 20.38"
                     /tool="antismash"
     gene            23206..24033
                     /locus_tag="KV381_RS32345"
                     /old_locus_tag="KV381_32345"
     CDS             23206..24033
                     /EC_number="3.1.-.-"
                     /GO_function="GO:0016788 - hydrolase activity, acting on
                     ester bonds [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007449852.1"
                     /locus_tag="KV381_RS32345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_32345"
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="WP_030623226.1"
                     /transl_table=11
                     /translation="MADDSRNNQQHIIGSYAAIGDSFTEGVGDPGPDGTYVGWADRFAV
                     LLADRLPAPDTEAGPEDSPHGDFRYANLAVRGRLLDQIVEEQIPRAKELAPDLVSFCAG
                     GNDIIRPGTDPDDLAERFERAVADLSNAVGTVMVTTGFDTRGVPVLRHMRGKIATYNVH
                     LRAIADRYQCPVLDLWSLRSVQDRRAWDADRLHLSPEGHTRVALRAAQVLGHAVPADPD
                     QPWPPQAQRSPFDERRDNIQWAREYLVPWIGRRLRGESSGDHVEAKRPDLLPL"
     gene            complement(24045..24962)
                     /locus_tag="KV381_RS32350"
                     /old_locus_tag="KV381_32350"
     CDS             complement(24045..24962)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012378201.1"
                     /locus_tag="KV381_RS32350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_32350"
                     /product="STM4011 family radical SAM protein"
                     /protein_id="WP_218786915.1"
                     /transl_table=11
                     /translation="MDLTILYRGPLASCDYDCPYCPFAKRRDSRAQLMADREALERFTC
                     WAAAQTGDRLSVLFTPWGEGLVRSWYRRALTELSRLPHIARVAIQTNLSGRTDWLADAD
                     PERIALWCTYHPGQTPYDRFLGKCRDLSAKGIRYSVGVVGFDEHLEEARRLRAALPGEV
                     YLWVNAAEGHTYTDAEAARWTELDPLFPYSRDPHRSAGLPCRTGESVISVDGDGTVRRC
                     HFVKAELGNLYDGSYRRALGPRACPLAVCDCHIGYVHLESLPLYDVFAGGVLERIPAER
                     PPGTPPDGLVVPNASRRALPLLEP"
     gene            complement(24970..26352)
                     /locus_tag="KV381_RS32355"
                     /old_locus_tag="KV381_32355"
     CDS             complement(24970..26352)
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010058004.1"
                     /locus_tag="KV381_RS32355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_32355"
                     /product="STM4012 family radical SAM protein"
                     /protein_id="WP_218786916.1"
                     /sec_met_domain="PF04055 (E-value: 8.8e-16, bitscore: 57.4,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTLTTRTPAPPAVRPYESYVYAYPHKTAYRPLADRPSLRSLWAAE
                     PKDALSLYLHIPFCEVRCGFCNLFTRIGAPEELTTRYLDALERQAVAVREALGDEEPVR
                     FAAAAFGGGTPTFLTAGELERLCDIAEKRMGADLGAVPLSVETSPATATADRLAVLADR
                     GTTRISIGVQSFVDEEARAAVRPQRRADVEAALGRIREARIPVLNIDLIYGIDGQTERS
                     WLASLDAALAWRPEELYLYPLYVRPLTGLHRLGAAAGAEARALEDAAWDEQRLRLYAMG
                     RDHLLAHGYEQVSMRMFRRTDVPREQEGPEDYACQTDGMIGLGCGARSYTAALHYSFDY
                     AVDMREIRSIIDRFTATEDFSRAEVGRYVDVAEARRRHLLQSLLQAAGLPVADYRARFG
                     TDPGADFPAELAEFAARGWLDSSAPEGLLRLSPAGLAHSDALGPALFSPGVRAAMAAYE
                     RK"
ORIGIN
        1 tccgcgaaga aggtggacct agccggaaac cctggagatg aggaaggacc gattgctgcg
       61 ccgggaaggc gtcgtcgcga ccgtcatcaa cctcagctcc tctcgaaagg tcccggtgac
      121 accgggttcc gctccaccac gagactcgaa cgtctcagcg actccaccct agcaccgacc
      181 cctcgcgcct ctcagtggca gaggtgcgcc tcgtgctcgg cgtggccgct cggctccagc
      241 tggaaggtgc agtgctccac gtcgaagtgg tccccgaggc agccctgcag ctcgtgcaga
      301 accttctcgt gtcctatcga gtccagcatc tcctggcgca ccaccacatg ggcggagagc
      361 accggcatgc ccgaggtgat cgtccaggcg tgcaggtcgt ggacgtccag gactccgggc
      421 agcgccgtga tgtgggcccg tacctccgcc atgtccacgc ccttgggcgc cgcctccagc
      481 agcacgttca gggtctcccg cagcagcttc accgtccggg ggacgatcat caggccgatc
      541 gccagcgagg cgatcgggtc ggcggcctgc cagccggtcg ccatgatgac gcccgccgag
      601 acgatcacgg cgatcgagcc cagggtgtcg gccatcacct ccagataggc gccccgcacg
      661 ttcaggctct ccttctgccc gcgcatcagc agggacagcg agacgatgtt ggccaccagg
      721 ccgaccgcgg cgaacgcgat ggcgagtccg cccttcgtct cggccggggt gatgaaccgc
      781 tcgaccgcct cgaagaccag atagccgccg acccccagca gcagcagaca gttggcgagg
      841 gccgccagga tctccgcacg ggcgaagccg aaggtgcggt tcgggccggc cgggcggttg
      901 gcgaagtgga tggcgagcag cgccatgccg agccccaggg cgtcggtggc catgtgggcg
      961 gcgtccgcga tcagggccag cgagtcggag aggacgccgc cgacgatctc catcaccatc
     1021 acgctcagcg tgatcgcgag ggccacccgg agcctgcccc ggtacgcggc ggccgccgtg
     1081 ccggtcgcag gcggcccgcc gtgcgtatgt ccgtgatcgt ggccagcccc catgcgaaac
     1141 gcctccaggt ccctaggacg cgccggggcg gaaccgcccc gaccaggcca gtgaactacg
     1201 ggtggggggt atggggcaac acgggactga acaccgttgt catgtgctct gacctgcgga
     1261 aacgttccgc aggtcagggc gttgacacga tcaccgacgc cacggggaac cgatcacgga
     1321 cgggcctcgg gatggcgcag ctgccagccc tcccaggccg actcgaccat ctcgcgcaca
     1381 ctccgccgtg ccgtccagcc gagctcctcg gtgatccgcg cggccgacgc caccgccttc
     1441 ggcgcgtcac cggcccggcg cggctccacc accggctcga gtccgtgacc cgtcacctcg
     1501 ccgatcacct cggccagctc ccgcaccgag acgccctcgc cccggccgac gttcagcgtc
     1561 aggtcgacgg cgtccgcccc gtccagccgc cgcgcgacgg cgaggtgcgc ctccgccagg
     1621 tcggcgacgt ggatgtagtc gcggacgcag gtgccgtccg gcgtcgggta gtcgtcaccg
     1681 aagatccgcg gggcctcgcc gcgcgtcagc cgctcgaaca tcatcggcac gatgttgaag
     1741 accccggtgt ccgcgagctc cggtgcggcg gagcccgcca cgttgaagta ccgcagacag
     1801 gcggtcgaga tcccgtgggc cttcccggtg gcccgcacca gccactcccc ggtgagcttg
     1861 gtctcgccgt acgggttgat cggcaggcag ggcgtctcct cggtgatgag ctccacgtcc
     1921 ggtacgccgt agacggccgc cgacgacgag aagaggaagc gccgcacacc cgccgcgacc
     1981 acggcctcca gcagcacgcc cagcccggcg acgttctccc ggtagtacag cagcggcttc
     2041 tccacggact cgccgacctg cttcttcgcc gcgagatgca ccacaccgct caccgtgtgc
     2101 ccggccagca cccggtccag cagggcccgg tcggaggccg agccctccac cagggtcacg
     2161 tcctcgggca gccggtccac gatgccgctg gagcggtcgt cgagcaccac gacccgctcg
     2221 cccgccgcca ccatggcccg cgccacgtgt gccccgatat aacccgcccc gcctgtgatc
     2281 agccatgtca tgaccgtcag cctaagggcc cgccgtccgc ggcccggccc gcgggtttgt
     2341 gggccgggcc cccgatcgat gatgatgatc gcgaacggcg accgcgcttg cggatccacc
     2401 cgaacagcgc acaaacgggt ggtgaactca gccttccgtt catcggatag cctcagccga
     2461 cacgccgccg gcccgtctcg tggccgtgcg gccgtgtgtc gtccccgtca gtgccaagga
     2521 gtgagttcgt ctgtcgaccg ccatcctcac cggtacgccg gtacccgggt cgtcgctcgc
     2581 ggacgatctg cggtccctgg gcttcgatgt gcagaccgcc gtcgacgccg gtgacgccgc
     2641 agccctgctc gccgccgttc cggccggccg ccgggtcgcc ctcgtcgacc cgcgcttcgt
     2701 gggccacgtc cacgcgctgc ggctcggact gaccgacccg cgcttcgccg tcgccaccgt
     2761 gcccggcgcg ctcaccgccc ggcccgaggc gcgcggcgcc ctgctgagtg cgctccggcg
     2821 caccacggcc gccgtcggcg cgggcgcccc ggtcgtcgag ccggacaccg accccgcgcc
     2881 cgaggaccgc accgtccccg gccggatcgc cgtggcactg gaggccgacg gcaccgccgt
     2941 acagcgcccc gccctcggct cgctcgtcgc ggccgtcccc acggacccgg agcagcgggc
     3001 cgccgccgag gcgggcctcg cctcggtcga cgacgaggcc gtacggctgc gcagcgcggt
     3061 gaaggcgcac gacggcttct tcaccacctt ctgcatcagc ccctactccc gctacatcgc
     3121 ccgctggtgc gcccgccgca acctcacccc gaaccaggtc accaccgcct cgctgatcac
     3181 cgcgctgatc gcggcgggcg cggcggccac cggcacccgg ggcggctatg tcgccgccgg
     3241 gatcctgctg atggtctcct tcgtgctgga ctgcaccgac gggcagctcg cccgctactc
     3301 gctgcagtac tccacgatgg gggcctggct ggacgccacc ttcgaccggg ccaaggagta
     3361 cgcgtactac gcggggctcg ccatcggcgc cgtacgcggc ggtgacgacg tatgggtcct
     3421 ggcgctgggc gcgatggtcc tccaggcctg ccgccatgtc gtggacttct cgttcaacga
     3481 ggccaaccac gacgcggtcg ccaacaccag ccccaccgcc gccctctccg gcaagctcga
     3541 cagcgtcggc tggacggtct gggcgcgccg gatgatcgtg ctgccgatcg gcgagcgctg
     3601 ggccatgatc gcggtcctca ccgcgctcac cacgccccgc atcgtcttct acgccctgct
     3661 catcggctgc gcgctcgccg cctgctacac cacagcgggc cgtctgctgc gctcgctgac
     3721 ccgcaaggcg cgccgtaccg accgcgccgc gcaggccctg gcggacctcg ccgactccgg
     3781 cccgctcgcc cagggcgtcg cggccgtcgc ccccgggctc cggggcgcgt tcaccgctcc
     3841 ggccgtcgcc ctgctcggca cgctcgtgat gatcggcggg gcgctcttcc tcccgtacgg
     3901 cagctggctc accgtcgccg ccgcggcggt gtacgtggtc ctctccggcc tcgccgtcgc
     3961 ccgcccgctc aagggcgcgc tcgactggct ggtgccgccg ttcttccggg ccgcggagta
     4021 cgtcacgatc ctggtgctgg cggcccgcag cgacgtcccg cacgccgttc cggcggcctt
     4081 cgggctggtc tcggccgtcg cctaccatca ctacgacacg gtgtaccgca ttcgcggagg
     4141 caccggcgcg ccgccccagt ggctggtgcg gacgatcggt ggacacgagg gccgtaccgc
     4201 gctggtggcc gtcctcgccg ccgtactcac ccacgcttca ggtttcacca cggccctgac
     4261 cgcgctcgcg gtcgccgtgg ctctggtggt gctcgtggag tccatccgct tctgggtgtc
     4321 ctcctcggcg cccgccgtac acgacgaagg agaactcgca tgatcggcct cgtactggca
     4381 gccggtgcag gacgacgtct gcgcccctac acggacacgc tccccaaggc gctcgtccct
     4441 gtcgacggcg acaagacggt cctcgacctc acgctcgcca acttcgccga ggtcggactc
     4501 accgaggtcg cgatcgtcgt cggctaccgc aaggaggccg tctacgcccg caaggccgag
     4561 ctggaggcga cctacggcct caccctcacg ctgatcgaca acgacaaggc cgaggagtgg
     4621 aacaacgcct actccctgtg gtgcgcccgt gacgtcatca agcgcggcgt gatcctcgcc
     4681 aacggcgaca ccgtgcaccc ggtctccgtc gagaagaccc ttctggacgc ccgcggcaag
     4741 ggccagaaga tcatcctcgc cctggacacc gagaagagcc tcgccgacga ggagatgaag
     4801 gtcatcaccg cggagggcaa gggagttcag cgcatcacca agctgatgga cccggccacc
     4861 gcgaccggtg agtacatcgg cgtcaccctc atcgaggccg aggccgccga ggagctggcg
     4921 gacgcgctga agaccacctt cgagcgcgac cccgacctct actacgagga cggctaccag
     4981 gagctggtca accgcggctt caccgtggac gtggccccca tcggcaccgt gacctgggtc
     5041 gagatcgaca accacgacga cctcaagaag ggccgtgaga tcgcgtgcca gtactgaccc
     5101 ggctcattcc gtccccggtc gtcgtcgaca tccggcgcgg cgccatggac gatctggcgg
     5161 gtcttctggc cgatcagcgg atctccacct cgggcaagct cgccatcgcg atcagcgacg
     5221 gctccgggcg cgccctcagg gagaggctcg ctccggtcct gccgggtgcc gactggtatc
     5281 cggtctccga cggcacgatc gactccgcgg tgaagctcgc cgacggcatc aagggcaacc
     5341 ggtacgacgc cgtcgtcggc ctcggcggcg gcaagatcat cgacgtggcg aagtacgccg
     5401 cggcgcgggt cggcctcccg ctggtcgccg tcgcgacgaa cctctcgcac gacggcctgt
     5461 gctcgccggt cgccacgctc gacaacgaca acgggcgcgg ctcctacggg gtccccaccc
     5521 cgatcgccgt ggtcatcgac ctcgacgtga tccgtgaggc gcccgcccgt tacgtccgtt
     5581 ccggcatcgg cgacgcgatc tcgaacatct cctgcgtcgc cgactgggag ctggcccacg
     5641 aggtcaacgg cgaggagatc gacggactcg cggccgcgat ggcccgccag gccggcgagg
     5701 ccgtgctgcg ccacccgggc ggcgtcggcg acgacgcctt cctgaaggtg ctggccgagg
     5761 ggctcgtgct caccggtatc tcgatgtcgg tcgcgggcga ctcgcgcccg gcgtccggcg
     5821 cctgccacga gatcaaccac gccttcgacc tgctctaccc ccagcgcgcg gccagccacg
     5881 gcgagcaggt cggcctcggc gcctgcttcg ccatgcatct gcgcggtgcc cgccaggagt
     5941 cgctcctgat ggcatcgata ctgcgccgcc acggtctgcc ggtcctgccg gaggagatcg
     6001 ggttcagcgt cgacgagttc gtcaaggccg tcgactacgc gccgcagacg cgtccgggac
     6061 gcttcacggt cctggagcac ctcaacctgt ccaccgacca gatcagggac gcgtacgccg
     6121 actatgcctc gaccatcagt agctgaactc cgtccggtcg tgcacccccc gggggtgaag
     6181 gaccggcgca gcggcgagca ctgggccggg cgcatgtaca tgcgcgaggt ctcgctgcgc
     6241 gtggaccgct acctggtcaa cacccgcgtc acgccgaacc aggtcacgta cgtgatgacg
     6301 ctggccggtg cgctggccgc cccggcgctg ctggtgccgg gcgtctgggg cgccgtgctc
     6361 ggtgtggtga tggtccagct ctacctgctc ttcgactgcg tggacggcga gctggcccgc
     6421 tggaagaagc agtactcgct cagcggggtc tatctggacc gggtcgccgc ctatctgtgc
     6481 gacgcggcgg tgctcgtcgg cctcggcctg cgcgccgccg acatctgggg cgagggccgg
     6541 atcgactggc tctgggcctt cctcggcacg ctggccgcgc tcggcgcgat cctgatcaag
     6601 gccgagacgg acctggtggg cgtggcccgc caccagggcg ggctgccgcc ggtcaaggag
     6661 gcggcctccg agccgcgctc ctccggcgtg gcgctggccc gcaaggccgc cgccgcgctc
     6721 aagttccacc ggctgatcct cggcatcgag gcatccctgg tgatcctcgt ggtggccgtc
     6781 gtggacgcga tcgggggcga cctcttctac acccgcctga ccgtggcggt catggccggc
     6841 atcgcgctgc tgcagaccct gctgcacctg gtgtccgtcc tggcgtccag caggctgaag
     6901 tgaccttccc catgaaactg ggcgcggtga tcatcaccat gggcaaccgc ccggacgagc
     6961 tccgcgccct cctcgattcg gtcaccgccc agcacggtga ccggatcgag gtcgtggtgg
     7021 tcggcaacgg cgccccggtg cccgatgtgc ccgccggggt gcgcacggtg gaactgcccg
     7081 agaacctggg catccccggc ggccgcaacg tcggcatcga ggcgttcggc ccctgcggtg
     7141 cggacgtgga cgcgctgctc ttcctggacg acgacgggct gctgccgaac cggaacaccg
     7201 ccgagctgtg ccggcaggcg ttcgaggccg atccgaagct ggggatcgtc accttccgga
     7261 tcgccgaccc ggagaccggc gccacccagc ggcggcacgt gccccggctg cgggccgccg
     7321 acccgatgcg ctcctcgcgg gtgacgacgt tcctcggcgg cgccaacgcg ctacgcacca
     7381 aggtcatcgc cgaggtgggc ccgctgccgg aggacttctt ctacgcgcac gaggagacgg
     7441 acctggcctg gcgggcgctg gacgcggggt ggatgatcga ctaccgcgcg gacatggtgc
     7501 tgaaccaccc caccaccgcc ccgtcccggc acgcggtcta ccaccgcatg gtggcccgta
     7561 accgggtctg gctcgcccgc cggaacctgc ccgccccgct ggtccccctc tacctcgggg
     7621 tctggctgct gctgaccctg gtgaggcgtc cgtcaccgcc cgcgctgaag gcatggttcg
     7681 gcggtttccg ggaaggctgg tcgacgccct gcgggcctcg gcgtccgatg aagtggcgta
     7741 cggtgtggcg gctgacgagg ctgggccgac ctccggtcat ctgagaggct ttcctctgag
     7801 agcatgaggc gtattttctt tccggaacct gtccgcctga gccgcgcccg cgactggctg
     7861 cgcgtgaaga cgagagtttc aacttgtgag tgacacgacc cacgacggtg gggtagccct
     7921 cgggaccccg ccgtccgccg acgagggcct cggcgcggcc cagctggccg ccaagtacgg
     7981 cctgaccgtg agcggcgccc ggccggggct gttcgcgtac atgcgacagc tctggggccg
     8041 acgccacttc atcctggcct tctcccgggc gaagctgacc gctcagtaca gccaggccaa
     8101 gctcggccag ctgtggcaag tggtcacgcc cttgctgaac gcctgtgtct attacctgat
     8161 cttcgggctg atcctgggga ccagggaggg gattccccac gacgtcttcg tgccgttcct
     8221 ggtcaccggc gtcttcgtct tcaccttcac ccagagctcg gtcatggccg gtgtccgggc
     8281 catctccggc aacctcggcc tggtccgggc cctccacttc ccccgggcct cgctgcccat
     8341 ctccttctcg ctccagcagc tccagcagct gctgttctcg atgatcgtgc tggtcgcggt
     8401 cgccgtcatc ttcggcagct acccctcgct gtcgtggctc ctggtgatcc ccgccctgat
     8461 tctccagttc ttcttcaaca ccggtctggc cctcgtcatg gcgcggctcg gctccaagac
     8521 ccccgacctc gcgcagctga tgccgttcgt catgcgcacc tggatgtacg cctcgggcgt
     8581 catgttctcc atcccggtga tgctcaagga caagccggcc tggatcgccg acgtactgca
     8641 gtacaacccg gcggcggtct acatggacct ggtccgcttc gcgctgatcg acggttacgg
     8701 ctccgagaac ctgccggacc acgtctgggc cgtcggcctg ggctgggccg tgctgctggg
     8761 cgtcgtggga ttcgtgtact tctggaaggc ggaggagcgg tacggccgtg gctgacgaca
     8821 acgcacaggg acgcatcccc acggtgatcg ccgacgacgt gcacatcgtg taccgcgtca
     8881 acggcacggg cggcggccgc ggcagcgcca ccgccgcgct gagccgcatg atgcggcggg
     8941 gcaagggcga gccgcgcggc gtccggaagg tgcacgcggt ccgcggggtc tccttcaccg
     9001 cctaccgcgg cgaggccatc ggcctcatcg gcaccaacgg ctccggcaag tcgacgctgc
     9061 tgcgcgccat cgccggtctg ctgccgaccg aatccggcca ggtgtacacg gacggccagc
     9121 cctcgctgct cggcgtgaac gcggcgctga tgagcgatct gaccggcgag cgcaacgtcg
     9181 tgctcggcgg cctggccatg ggcatgaccc aggccgaggt ccgctcccgc taccaggaga
     9241 tcgtcgactt ctccggcatc aacgagaagg gcgacttcat caccctgccg atgcggacgt
     9301 actcctccgg catggccgcg cgactgcgct tctcgatcgc cgccgccaag aaccacgacg
     9361 tcctcatgat cgacgaggcg ctggccaccg gcgaccgcaa gttccgggtc cgctccgagg
     9421 agcggatccg cgagctgcgc aaggaggcgg gcacggtctt cctggtcagc cacaacaaca
     9481 agtcgatcag ggacacctgc gaccgcgcgc tctggctgga gaagggcgag ctcctcatgg
     9541 acggccccac cgaggaagtc ctcaaggcgt acgaacgcga aacgggcaag tagccccagc
     9601 tctccccgtg gcccccgccg gaccgttccg gcgggggccg tgcggtgccc ggcagaccgc
     9661 ccgcagtagg cccccagggg cgatctcctc ccggcggatg acgtcaattc cgccgtacgc
     9721 ggggaaggtt gacggacacg gccgggaagc ggcggcgggc gctccacccc gccggtccgc
     9781 tgtgagctgt acaacgtaag ctgtagcggt gctgattcat ggcaagtagg gcgatacgcc
     9841 ccggcaccgt ccgctctgcc gcagtgcact cggaagaatg aacggcgtgt ccgaaaaggg
     9901 ttgttttggg tcagcagtgt agaacgggag atgtgacggc aatgacggaa gatctccagc
     9961 tccgacgtgg tttcgccgtc cccgcgccgg gcggttcgca gtgacctctc cccccgaggc
    10021 gcgcatcggc gacgccaccc tcggcaaggc cgcggacgag aacttccccg tggcgccctt
    10081 cttcctgccc cgcgcctggc gcgacgacct gatggcggtc tacggattcg cccggctcgt
    10141 cgacgacatc ggtgacggcg acctcgcacc cggtggcgcg gacgcccgcc acctcggcct
    10201 ggagccggag cagagcgacg accgcctcgc catgctcgac gccttcgagg ccgacctcca
    10261 ccgggtcttc gccaccaccg gcgatgagcc gcgccacccg ctgctgcgca acctgcgccc
    10321 caccgtgcgg cgccgcgcgc tcacccccga gcccttcctc ggcctgatcg aggccaaccg
    10381 ccaggaccag aagatccgcc gctacggcac ctacgccgag ctcgccgcct actgcgagct
    10441 ctcggcgaac ccggtcggcc gcctggtcct cgccctcacc ggcaccacga gcccggaacg
    10501 cgtccgccgc tccgacgcgg tctgcaccgc gctccagatc gtcgagcacc tgcaggacgt
    10561 ggccgaggac ctggcccgcg accggatcta tctgcccgcc gaggacatgg aacgcttccg
    10621 ggtcaccgag accgacctgg ccgcgcccac cgccggtgcc tccgtgcgcg ccctgatcgc
    10681 ctacgaggcc cagcgtgcga gcgacctgct ggacgagggc cccccgctgg tgggcagcgt
    10741 cgacggcagg ctcaagctgc tcctcgccgg attcgtcggg ggcggccgca gcgcgctcac
    10801 ggcgatctcg gccgccggat tcgacgtact gcccggaccg cccaagccca ccaagcccag
    10861 cctgctgcgc gaagtgggaa tcgtcttgcg aagagcgcgt ggagagaggt gagccggacc
    10921 gtggagggac agacgacgta catgtcgccg ccggtgcagg ccgcatacag ttactgcgag
    10981 gccgtcaccg gacagcaggc ccgtaacttc gcctacggca tcagactgct gccgtacgag
    11041 aagcggcagg ccatgtcggc gctgtacgcc ttctcccgtc gggtcgacga catcggcgac
    11101 ggggagctgg acccggagac caagcggacc cggctggaga gcacccgcga gctgctggag
    11161 cggatccgca aggacgcggt cgacgaggac gacaccgacc cggtggccgt cgcgctcgcg
    11221 gacgccgccc gccgcttccc gctcccgctc ggcggactcg acgagctgat cgacggcgtc
    11281 ctgatggacg tccggggcgc gacctacgag acctgggacg acctcaaggc ctactgccgc
    11341 tgtgtcgccg gagccatcgg acgcctcagc ctcggcgtct tcggcaccgc gccgggcgcc
    11401 cgcggggccg agcgcgccgc ggagtacgcc gacaccctcg gcctcgccct ccagctcacc
    11461 aacatcctgc gcgacgtccg cgaggacgcc ggcaacggac gcacctacct gcccgccgac
    11521 gacctggcca aattcggctg ctcggcaggg ttccaccgca ccaccccgcc ccccggctcc
    11581 gacttcgccg gcctcatcca cttcgaggtc cgccgcgccc gcgccctgtt cgccgagggc
    11641 taccggctgc tgccgatgct cgaccgccgc agcggcgcct gcgtcgcggc gatggccgga
    11701 atctatcgcc gcctcctcga ccggatcgag cgcgaccccg aggccgtcct gcgcggacgg
    11761 gtctcgctgc ccggccacga gaaggcctat gtcgcggtgc gcggcctgtc cggactggac
    11821 gcccgccaca tctcgcggct caccgccagg gggcgatcct gatggacgcc ggcacctccg
    11881 gccgccgggc aaccctccgg tggcccgacg cgtcacagac tgcgacgatc tccggggtga
    11941 ggacccggca gacggccacg acccgacggg aggggcacgc atgagcgacg agaccccgcg
    12001 ccccgtcgcc gtcgtcgtcg gcggcggact cgccggcgtc acggcggcgc tccgcctcgc
    12061 cgacgccgga ctggacgtga ccctcctgga agggcggccc cgcctcggcg gcctcgcctt
    12121 ctccttccag cgcggcgacc tcaccgtcga caacggccag cacgtctacc tgcgctgctg
    12181 caccggctac cgctggttcc tcgaccggat cgacgcctcc cacctggccc cgctccagga
    12241 ccgcctcgac gtgcccgtgc tggacgtcgg ccgggccgcc ggaccgcgcc tgggacggat
    12301 ccgccgcacc ggcctgcccg taccgctgca cctcgccggc gggctcgccg cctacccgca
    12361 cctctcgctc gccgagaagg cgagcgtcgg ccgggccgcc ctcgcgctcg gccgcctgga
    12421 ccccgccgac cccgagctgg accgcgtcga cttcgccacc tggctgcgcc gcaacggcca
    12481 gtccgagcgc accatcgagg ccctctggga cctcgtcggc gtcgccaccc tgaacgccac
    12541 cgccccgaac gcctccatgg cgctcgccgc gaaggttttc aagaccggcc tgctctccga
    12601 gcccggcgcc gccgacatcg gctgggccgc cgtgccgctc ggcgaactgc acgacaccct
    12661 cgcccgcaag gccctggaca ccgcgggcgt ccgcaccgag ctgcgcgcca aggccggctc
    12721 cctcacccgt accgaggacg gccgctggag cgtggagacg gcgggggagc ggatcaccgc
    12781 cgacaccgtc gtgctggccg tgccgcagac cgagacccac gacctgctgc ccgcgggcgc
    12841 gctggacgag ccggagctgc tgctcgacat cgacaacgcc ccgatcctca acgtgcacgt
    12901 catctacgac cgcaaggtgc tgcgcaggcc gttcttcgcc gcgatcggct ccccggtgca
    12961 gtgggtcttc gaccgcaccc acgcctcggg gctcacgggc cccgggcagt atctggccgt
    13021 ctcgcagtcg gccgcccagg acgagatcga cctgcccgtc gccgaactgc gctcccgcta
    13081 tctgcccgag ctggagcggc tgctgcccgc cgcccgcggc gccggcatcc gcgacttctt
    13141 cgtcacccgg gagcgcaccg cgaccttcgc gcccgccccg ggcgtcggac ggctgcgccc
    13201 cggcccccgc acccggctgc ccggccttca gctggcgggg gcctggaccg ccaccggctg
    13261 gcccgcgacg atggagggtg ccgtgcgcag cggcgccggt gccgccgacg cggcgctcca
    13321 ggacctcggc cgcccccttg gacatccgct gcaggaggcg gcatgagcag taccaccgga
    13381 acaagaggag agtctgtgac cccggcgaat ccggctttcg acaccgtggc ggacaccgcg
    13441 gacgtcaccg cgcttctgga gcgcggacga gccctgtcag cgccggtcct gcgggctgcc
    13501 gtggaccggc tcgcgccgcc catggacacc gtcgccgcct accacttcgg ctggatcgac
    13561 gccgagggac ggccctcgga cggcgacggc ggcaaggccg tgcgccccgc gctcgccctg
    13621 ctgtccgccg aagctgccgg cgcccccgcc gaggccggca tccccggcgc ggtggccgtc
    13681 gaactcgtgc acaacttctc gctgctgcac gacgacctga tggacggcga cgagcagcgc
    13741 cgccaccgcg acaccgtctg gaaggtgcac ggccccgccc aggcgatcct ggtcggcgac
    13801 gcgctcttcg cactcgccta cgacctgctg ctggagctcg gcacggtcga ggcgggccgc
    13861 gcggcccgcc ggctgaccac cgccacccgc aagctcatcg acggccaggc ccaggacatc
    13921 tcctacgagc accgcgagcg ggtcaccgtc gaggagtgcc tggagatgga gggaaacaag
    13981 accggcgcgc tgctggcctg cgccgtctcc atcggcgcgg tgctcggcgg cgccgacgac
    14041 cgcaccgccg acaccctgga ggcgtacggc tatcacctcg gcctcgcctt ccaggccgtc
    14101 gacgacctgc tcggcatctg gggcgacccg gagtccaccg gcaagcagac ctggagcgac
    14161 ctgcgccagc gcaagaagtc cctgcccgtc gtcgcggcgc tcgccgcggg cggcgaggcg
    14221 tccgagcggt tgggcgagct gctcgccgcc gacgccaaga gcaacgactt cgacagcttc
    14281 tccgaagagg agttcgccgc ccgcgcggca ctcatcgagg aggcgggcgg ccgcgagtgg
    14341 accgcccagg aagcccgtcg tcagcacgcg gtcgccatcg aggcgctgca cgccgtcgac
    14401 atgccccacc gggtgaggga gcagctcacc gagctcgccg acttcgtggt ggtacgaaag
    14461 agatgatcac tttccgcata tgactcgcag tcgccggccg gcgcccctca ccgggcgccg
    14521 gccgacggag accccagcac agcagagaac cgactgcacg taaggggaag ctcatgacag
    14581 cgacgaccga cggatcgacc ggggccgcga acctctccgg ggccccggcc gacgatccga
    14641 ccgacacgac caccgccgcg gacgacgtga ccgccgccgc gcgacgggcc gcggaacgct
    14701 ccgtggagca cctcctcggc agacaggacg agcagggctg gtggaagggc gacctcgcca
    14761 ccaacgtcac gatggacgcc gaggacctgc tcctgcgtca gttcctcggc atccaggacg
    14821 cggagacgac ccgggcggcc gccctcttca tccgcggcga acaactcggc gacggcacct
    14881 ggaacacctt ctacggcgga ccgggcgacc tctccgccac gatcgaggcg tacgtcgccc
    14941 tgcggctggc cggggaccgc cccgacgaac cgcacatggc ccgagcctcc ggctggatca
    15001 gggagcaggg cggcatcgcg gcggcccgcg tcttcacccg catctggctg gccctgttcg
    15061 gctggtggaa atgggacgac ctccccgaac tgccgcccga gctgatgttc ttccccaagt
    15121 gggtcccgct caacatctac gacttcggct gctgggcccg gcagaccatc gtgccgctca
    15181 ccatcgtctc cgcgaagcgc ccggtccgcc ccgcgccctt cgccctggac gagctgcaca
    15241 ccgacccgga ccaccccaac ccggccagga agctcgcccc gcccgccagt tgggacggac
    15301 tcttccagcg cctcgacaaa gggctgcacc tctatcacaa ggtcgccccg cgcccgctgc
    15361 gccgtatcgc gatgaacgtg gccgcccggt ggatcatcga gcgccaggag aacgacggct
    15421 gctggggcgg gatccagccg cccgccgtct actccatcat cgcgctgcac ctgctcggct
    15481 acgacctcga ccacccggtg atgaaggccg ggctggcctc gctcgaccgg ttcgccgtcc
    15541 ggcgcgagga cggcgcccgg atggtcgagg cctgccagtc gcccgtctgg gacacctgcc
    15601 tggccaccat cgcgctggcc gacgccggac tcagacccga ccacccggcg ctggtgaagg
    15661 ccgccgactg gatgctggcc gaggagatca cccgacccgg tgactgggcg gtgcgaaaac
    15721 ccgaactggc cccgggcggc tgggcgttcg agttccacaa cgacaactac ccggacatcg
    15781 acgacacggc cgaagtcgtc ctggcgctgc gccgggtgcg ccaccccgac cccgcccgga
    15841 tgcaggcggc catcgaccgc ggggtccgct ggaacctcgg gatgcagtcc cgcaacgggg
    15901 cctggggcgc gttcgacgcc gacaacacca gccccttccc caaccggctt cccttctgcg
    15961 acttcggcga ggtcatcgac ccgccgtcgg ccgacgtcac cggccatgtc gtggagatgc
    16021 tcgccgtcga gggactcgcg aaccaccccc gtacccgcga gggcatcgag tggctgctcg
    16081 ccgaacagga ggcgtgcggc gcctggttcg gccgctgggg cgtcaactac gtctacggca
    16141 ccgggtccgt ggtgcccgcc ctgatcgccg ccggactgcc cgcaggacac cccgcgatcc
    16201 gccgggccgt cggctggctg gagtccgtcc agaacgacga cggcggctgg ggcgaggacc
    16261 tgcgctccta ccaggaggag aagtggatcg gacacggtga gtccaccgcg tcccagaccg
    16321 cctgggcgct gctcgccctc ctcgctgcgg gacgccggga caccgcgtcc gtcgcccggg
    16381 gcgtcacctg gctcaccgag gcgcagcagg ccgacggctc ctgggacgag ccgtatttca
    16441 ccggcaccgg cttcccctgg gacttctcca tcaactacca cctctaccgc caggtcttcc
    16501 cgctcaccgc actcgggcgt tacgtgtacg gcgacccgtt cgccgaccgc gcggacgccg
    16561 tcgagggggc ctgatggacg atccgagagg gcccgggagc cccgtgccgc cgctgctggt
    16621 cgcctgcgcc ctcggcatcg agcaggtggc cctgcgcagt ggcaggggcg ccccgggccc
    16681 ggtccgggtc ctgcgcaccg gaatgggccc ccgggcggcg gagacggccg tggcgcgcct
    16741 cctgggcccc gacggggttc cggacgccgc cgtgatcgcc tccgggttct gcgccggcct
    16801 cctcccgggg atgcaccccg gggacctggt cgtcgccgag gagacccggg acgtggacgg
    16861 caccaccccc tgcaccggca ccggcgtcct ggtcgccgcc ctcgccaggg ccgtccccgg
    16921 ccgcaccgtc cacaccggcc ccctgaccgg ctccgaccac gtcgtacggg gctccgagcg
    16981 ggccgcgctg cgggcgggcg gggccatcgc ggtggacatg gagtccgccg cgacactgcg
    17041 taccgccctg tgtcacggac cgcgcccggt tgcggccgtc cgggtggtcg tggacgctcc
    17101 agagcatgag ctcgtccgca tcggcaccgt acgcggtgga atatcggcgt tccgcgttct
    17161 tcgtgccgtc cttccggctt tctacgaatg gcaccgatct ttactgctcc ccaggaggtg
    17221 agctagatgg ccatgccgct ccgccagacc atcaaggttg cgacgtatct cttcgaacag
    17281 aagctccgca agcgtgagaa gttcccgctg atcgtcgagc tggagccgtt gttcgcctgc
    17341 aacctcgcct gcgagggatg cggcaagatc cagcacccgg ccggtgtcct gaagcagcgc
    17401 atgccggtcg cccaggcggt gggcgcggtg ctcgaatcag gggcccccat ggtgtccatc
    17461 gccggtggcg agccgctgat gcatccgcag atcgacgaga tcgtgcgcca gctcgtcgca
    17521 cggaagaaat acgtcttcct ctgcaccaac gcgatgctga tgcggaagaa gctcgaaaag
    17581 ttcactccgt ccccgtactt cgccttcgcc gtccacatcg acgggctgcg cgagcggcac
    17641 gacgagtcgg tcgccaagga aggcgtcttc gacgaggccg tcgccgcgat gaaggaggcc
    17701 aaggcgcgcg gcttccgcgt caccaccaac tccaccttct tcaacaccga caccccgcag
    17761 accatcatcg aggtcctgaa ctacctcaac gacgacctca aggtcgacga gatgatgatc
    17821 tcgcccgcct acgcctacga gaaggccccc gaccaggagc acttcctcgg cgtcgaccag
    17881 acccgcgaac tcttcaagaa ggccttcgcg ggcggcaacc gggcccgctg gcggctcaac
    17941 cactcgccgc tcttcctgga cttcctggag ggcaaggcgg acttcccgtg caccgcgtgg
    18001 gcgatcccga actactcgct cttcggctgg cagcgcccgt gctacctgat gagcgacggt
    18061 tacgtaccga cgtaccgtca gctcatcgag gagaccgact gggacaagta cggccgcggc
    18121 aaggacccgc gctgcgccaa ctgcatggcg cactgcggct acgagcccac ggcggtgctc
    18181 gccacgatgg ggtccctcaa ggaatccctg cgcgcggccc gggagaccgt caccagcaac
    18241 cggtgagccg gtgaccgacg aggtacggcc ggccgccgcg ggtttcccgg ggcggccggc
    18301 cgcacgacgc agcacatccg aaggagaaga gcgggcgatg acggacggcg gatcccaggg
    18361 cttcgatctg gcgcggctcc tcgccgagcg cgggtccgag cggtacgagc tgcacgcgcg
    18421 ccacctcaac caccagctgc cgcgcatgct ccacaccatc ggcttcgaca aggtctacga
    18481 gcgcgccgag ggcgcgtact tctgggacgc ggagggcgac gactacctcg acatgctcgc
    18541 cggcttcggc gtcatgggcc tgggccgcca ccaccccgtc gtccggcagg ccctgcacga
    18601 cgtcctggac gcccagctgg ccgacctcac ccgcttcgac tgccagccgc tgcccggact
    18661 gctcgccgag aagctgctga cccacagccc gcacctggac cgcgtcttct tcgggaacag
    18721 cggtacggaa gcggtcgaga cggcgctgaa gttcgcccgg tacgccaccg ggaggccccg
    18781 gatcctctac tgcgaccacg ccttccacgg gctcaccacc ggatccctgt cggtcaacgg
    18841 ggagagcggc ttccgcgacg ggttcgcccc gctgctcccc gacacggccg tgccgctcgg
    18901 cgatctggac gcgctgcgcc gcgagctgaa gcggggcgat gtcgcggcgc tggtcgtcga
    18961 gccgatccag ggcaagggcg tgcacgccgc gccgcccggc tatctgcggc aggcccagga
    19021 gctgctgcac cggcacaagg cgctcctgat cgccgacgag gtgcagacgg gcctgggccg
    19081 gaccggcgac ttctacgcct accagcacga ggagggcgtg gagcccgatc tggtctgtgt
    19141 ggccaaggcg ctctccggcg gctatgtgcc cgtcggcgcg accctcggca aggactggat
    19201 cttccgcaag gtctactcct cgatggaccg ggtcctcgtc cactccgcga gcttcggctc
    19261 caacgcgcag gcgatggcgg ccgggctcgc cgtcctgacc gtgatggagg acgaggagac
    19321 cgtcgcgaac gcccggcgca ccggcgatct gctccgcgag cggctggcgg ccctggtgga
    19381 ccgctacgag ctgctgcacg aggtccgcgg gcgcgggctg atgatcggca tcgagttcgg
    19441 ccggccgtcg tcgctgaagc tccgcagccg ctggaccatg ctccaggcgg cccgcaaggg
    19501 gctcttcgcc cagatggtcg tggtgccgct gctccagaag caccggatcc tcacccaggt
    19561 ctccggcgac catctggaag tgatcaagct gattccgccg ctggtcatcg gggacgccga
    19621 ggtggaccgc ttcgtggcgg cgttcacgtc cgtcatggac gacgcgcaca gcggcggcgg
    19681 actgatgtgg gacttcggcc gcactctcgt caagcaggcc gtggccaacc gctgacgggc
    19741 gcccctttgc ctccggggca agttatttgc ctcggaggaa agatactggc ccaatggatc
    19801 catgaaccct ccggacgaag gggtgccgga cgagctcccc ggcgtcgcac cccgactgcg
    19861 tgacctgcgc cgaagccgtg gtctcaccct ggagaccgcc gcccggcggg ccgggctctc
    19921 cccggcccat ctctcccggc tggagaccgg ccgccggcag ccctcgctgc cgatgctgct
    19981 ggggctggcc cgtatctacg gtacgacggt ctccgagctc ctcggcgagc agccgcccga
    20041 acgggacgcg atcgtccgcg gcggcggctt cgagggggcg gaggcggacg gctggatgta
    20101 ccggcaggcg ggcggctccg gccgcgcgat gcaggccctg cgggtacgtg ttccgtacgg
    20161 ggcccagggc gacctggtcc gggtccatcc cggcgaggag tggctgtacg tcatggaagg
    20221 gcggctgcgg gtcgggctcg gcgacaccgt gcacgacctc gaacccggcg acagcgccca
    20281 cttcgactcg ctcaccccgc accggattgc ggccgtcgac cgcggcggcg cggagctgct
    20341 cttcgtccac accctgctgc agagtcccgc cgccgagctc tgtctcggca acgccctcca
    20401 cgcgcgctga ccggccgtcc ccgccggctc catccttcgc tccaccggcc gcgaggccga
    20461 cagagaggac cgtcatgtcc gattccgaac actacgaccc gctgggcccc ggacgtcgcg
    20521 tgaacgagga cccgcaggag aagcggatgc cgcgcggcgt cgtcatccgg ctcttcgcct
    20581 acctggtggc gggccacgtc atcgcgggct tcctctacct gctcttcgtg gtggccggga
    20641 gcaagtgacg gcccgccgcc gggcgggtca gtcctggtcg agcaggcgct cgcgcagccg
    20701 ctcccgggta ccggaggaga tcttcagccc ctcggtgagg tagcggtcgg tcgtgcccca
    20761 gttctcctcg atggtcgcga aggccgccgc gaggtaggcc ggccgcgccc cgaagagcgg
    20821 gtccagcagc tccagcacct cgggcgacat accggcctcg gacgcgtcgg agcgcttcac
    20881 gttgtagcgg cggtggaggt cgttggactt gaggtagtcc tcctcgatcg cctccacctc
    20941 cacgccgacc gccagcaggg cgaccgcgat cgagagaccg gcccggtcct tgcccgccgc
    21001 gcagtgcatc agggccggga cgctgtcctc ggccagcgcg tgcagcaccc ggctgtgctc
    21061 gacggtgcgg tcctcgatcg tcgcgcggta catccggatc atgcggtcga cgcccttgcc
    21121 gtccgcgagg accgagcgca gctgctcgat gttcccgtcg ctcaccagcc gccagaactc
    21181 cgcgccgtcg gccgggtcgg agagcggaat gctgacattg cggacaccgg gcagctcgat
    21241 gtcgtaaccg tcgaggcggt ggtcggcgga gtgccggaag tcgaagaccg tgtgcagtcc
    21301 gagcccgccg aggaaggccg cgtcctcggc ggtggcgtgc gccaggtggc cgctgcggta
    21361 gagccggccg aaggcggtgc gccgcccgtc cgtggtgggg agcccgccca cgtcgcggaa
    21421 gttgcggact ccggtcagca cggtctctgt cggcgggacc tgcggcacct gctgcgtcac
    21481 gggggctcct gggatctctg gcgtcggcgc ggctcgccgg cgagggcgct cccgtgacga
    21541 tacgacatcg attcgacaga aaatcatcac ggtcgacacc tcgatgcggg gtgccgacga
    21601 ggccggactg acccggcgtc aggagcaccg ccgacggcat gtccgtattg gtgtatttcg
    21661 cagaacatgc cccgctaatg ggggagatgg gatttcagag gtgagcggga tcatatccgt
    21721 gacggaccgt ggtgagcgcg ccccggggta tttcccttgc ccgtaaggaa atccaagatc
    21781 cgtaatccac ggagtgtgac gggaaatccg atgcgatatc gaatcgatga ttccggcgcg
    21841 caaccgatgg cttgttccgc tcgtcctgac cggtttacgg tcgccgcaat ccggacggac
    21901 cgcctaatcc tgccgccgcc cggaattcgc acccacccac tcacgtgtgg caggagcggg
    21961 ggaaccaggt aagccgccgg tccggagcga tccggaccgg ctcggggtga agtcgccgca
    22021 acgcgaccgg gcatctccag cccgaacccg acagctcacc tcgcaggcgc cggagaggaa
    22081 atcccccatg cccgcaaagg gtaagcaccg tcgtccgaag tccggcccga tctcccgcgg
    22141 cgtcctcgcc gcgggcaccg gtggcgccgc actcgccctc ccgctcatcg gcgccggcat
    22201 cgcgagcgcc gccgaccggg ccgctcccgc cgcgaagccc gccgccgcct cggtcgccgc
    22261 cgcgcacacc gccccgtcgg ccgctcccgc cgcgtcgaag gccgccccga aggcgtactc
    22321 cgtcgtctcc ggcgactacc tgtcgaagat cgcggccgag caccagctca agggcgggtg
    22381 gcagaagctg taccaggaca accgctccac cgtcggcgag aaccccggcc tgatccaccc
    22441 gggcatgaag ctgaccctcg gcgccaaggg ctccgccccg gccgagaagt ccgccgctcc
    22501 cgaggccgcc ccgaagaagg ccgctccggc cccgaaggcc gcgccgaagg aagccccgaa
    22561 gggcgacacc atctccgccg acgactccga gggctccggc gcctccgcgc agaccggctc
    22621 ctccgaggcc accggctccg gctggtccgc cccgctggcc aacgccaacg tcaccaccca
    22681 gtaccgcgct tccggcgcca gctggtccag cggctaccac accggctcgg acttccaggc
    22741 cgcctccggc acccccgtcc tcgccatcgg accgggcacc gtggtctcgg ccggcaacag
    22801 cggctcgtac ggcaacgagg tcgtcatcca gcacgaggac ggcatgtact cgcagtacgc
    22861 ccaccagtcc tcgctgaacg tctccgtcgg ccagaccgtc accggcggcc agcagatcgg
    22921 cctctccggc tccaccggca actccaccgg cccgcacctg cacttcgagg tccgcaccgg
    22981 cccgagctac ggctcggacg tcgacccgat cgcgtacctg cgtcagcacg gcgtctccgt
    23041 ctgaccgagc aggaccggaa gtgtccgagg ggcggtgcgc ggcggcgcac cgcccctccc
    23101 tttattccgg ctttaccaaa acctgaccgg gtggtctatc tcaccacccg tcaaccccgt
    23161 attacggtcg cgtaggtcac atcggacgat gcaggataag tccttgtggc agacgattcg
    23221 agaaacaacc agcagcacat catcgggtcg tacgcggcga ttggcgacag tttcaccgag
    23281 ggcgtcggcg accccggccc cgacgggacc tatgtcggct gggcggaccg cttcgcggtg
    23341 ctcctcgccg accggctccc ggcccccgac acggaggccg gccccgagga ctccccgcac
    23401 ggggacttcc gctacgccaa tctcgccgta cgaggacgtc tcctcgacca gatcgtcgag
    23461 gagcagatcc cccgtgccaa ggaactggcc cccgacctgg tcagcttctg tgcgggcggc
    23521 aacgacatca tccggcccgg caccgacccc gacgacctcg ccgagcgctt cgagcgtgcg
    23581 gtcgccgacc tgagcaacgc cgtcggcacg gtcatggtca ccaccggctt cgacacccgg
    23641 ggcgttccgg tgctgcgcca catgcgcggc aagatcgcca cgtacaacgt ccatctgcgg
    23701 gccatcgccg accgctacca gtgccccgtg ctggacctgt ggtcgctgcg ctcggtccag
    23761 gaccggcgcg cgtgggacgc cgaccggctg cacctctcgc ccgagggcca cacccgcgtc
    23821 gccctgcgcg ccgcccaggt cctcggccac gccgtgcccg ccgaccccga ccagccatgg
    23881 ccgccgcagg cccagcgcag ccccttcgac gagcggcgcg acaacatcca gtgggcccgc
    23941 gaatacctgg tgccgtggat cgggcgacgg ctgcgcggcg agtcctccgg cgaccacgtc
    24001 gaggcgaagc gtcccgacct gctgccgctg tagcggccgg gcgttcaggg ctccagcagg
    24061 ggcaacgcgc gccgggacgc gttcggcacc acgagcccgt ccggcggcgt gcccggcggg
    24121 cgctccgccg gtatccgctc caggacgccg cccgcgaaga cgtcgtacag cggcagcgac
    24181 tccagatgca catagccgat gtggcagtcg cacacggcga gcggacaggc ccgcgggccg
    24241 agcgcccggc ggtagctgcc gtcgtagaga ttgcccagct ccgccttgac gaagtgacag
    24301 cgccgcaccg tgccgtcgcc gtccaccgag atcaccgact cgcccgtccg gcagggcagc
    24361 cccgccgagc ggtgcggatc acggctgtag gggaacagcg gatccagctc cgtccaccgc
    24421 gccgcctccg cgtcggtgta cgtgtggccc tcggcggcgt tcacccagag gtagacctcc
    24481 ccgggcagcg ccgcccgcag ccgccgcgcc tcctccaggt gctcgtcgaa ccccaccacg
    24541 cccacgctgt agcggatacc cttcgccgac agatcccggc atttgcccag aaaccggtcg
    24601 tacggggtct gtcccgggtg gtacgtgcac cagagcgcga tccgctccgg atcggcgtcc
    24661 gccagccagt cggtgcggcc gctcagattc gtctggatcg cgacccgggc gatgtgcggc
    24721 agccgcgaca gctcggtcag cgcccgccgg taccaggagc gcaccaggcc ctcgccccac
    24781 ggagtgaaca gcaccgacag ccggtcgccc gtctgtgccg ccgcccagca ggtgaacctc
    24841 tccagcgcct cccggtccgc catgagctgc gcgcgactgt cccgccgctt ggcgaacggg
    24901 cagtacggac agtcgtagtc gcaggaggcg agcgggcccc ggtagagaat cgtcaggtcc
    24961 atgtccggct cacttccgct cgtacgcggc catcgccgcc cgcaccccgg gcgagaacag
    25021 cgccggaccc agcgcgtcgg agtgggccag acccgccggg gacaaccgca gcagcccctc
    25081 cggggccgag gagtccagcc agccccgggc cgcgaactcc gccagctcgg ccgggaagtc
    25141 cgcgcccgga tccgtaccga accgcgcccg gtagtccgcc accggcagcc ccgctgcctg
    25201 gagcagcgac tgcagcagat gccgcctgcg cgcctcggcc acatcgacat accggccgac
    25261 ctcggcccgg gagaagtcct cggtggcggt gaaacggtcg atgatcgacc ggatctcccg
    25321 catgtccacc gcgtagtcga aggagtagtg cagggccgcc gtgtacgaac gggccccgca
    25381 gcccaggccg atcatgccgt cggtctggca ggcgtagtcc tcgggaccct cctgctcccg
    25441 agggacgtcg gtccgccgga acatccgcat cgacacctgc tcgtagccgt gcgccagcag
    25501 atggtcccgc cccatcgcgt acagccgcag ccgctgctcg tcccaggcgg cgtcctccag
    25561 ggcccgcgcc tcggcgccgg ccgcggcgcc caggcggtgc agaccggtga gcgggcggac
    25621 gtacaacgga tacaggtaca gctcctccgg ccgccaggcc agcgccgcgt ccagcgaggc
    25681 gagccagctg cgctcggtct gcccgtcgat gccgtagatc aggtcgatgt tcagcaccgg
    25741 gatccgggcc tcgcggatcc ggccgagcgc cgcctccaca tcggcccggc gctgcgggcg
    25801 gaccgcggcc cgcgcctcct cgtccacgaa gctctgcacg ccgatgctga tcctggtcgt
    25861 gccccggtcg gccagcaccg ccagccggtc ggcggtggcg gtggcgggcg aggtctccac
    25921 ggagagcggg accgcgccca ggtcggcgcc catccgcttc tccgcgatgt cgcagagccg
    25981 ctcgagctcg ccggcggtca ggaacgtcgg cgtgccgccg ccgaacgccg ccgccgcgaa
    26041 ccgcaccggc tcctcgtcgc ccagagcctc ccgcacggcc acggcctgcc gctccagcgc
    26101 gtccagatag cgcgtcgtca gctcctcggg cgcgccgatc cgggtgaaga ggttgcagaa
    26161 gccgcagcgg acctcgcaga acggtatgtg gagatagagg gagagcgcgt ccttgggctc
    26221 cgccgcccac agcgaccgca gcgacgggcg gtccgcgagc ggccggtagg ccgtcttgtg
    26281 cggataggcg tagacgtagc tctcgtacgg ccggacggcg ggcggcgcgg gagtacgggt
    26341 ggtgagcgtc atcgggcggc ccccggttct ggcgatgcgg atgtctcgca cgcggatgtc
    26401 tcgcacgcgg gtggttcgca tgcgggtggt tcgaggaaga agtgggcgta cgggacggtc
    26461 cagacggccg ggtggccgag ccggtgaccg gtgtagccgt cgtcgccgta ggccgtgccg
    26521 tggtcggaac agacgatggc gaagcaacgg cggcggctgc tcgccgcggc gaag
//
