LOCUS       NZ_CP079114            13000 bp    DNA     linear   CON 06-SEP-2024
DEFINITION  Streptomyces sp. WY228 chromosome.
ACCESSION   NZ_CP079114
VERSION     NZ_CP079114.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. WY228
  ORGANISM  Streptomyces sp. WY228
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8286721)
  AUTHORS   Qin,S.
  TITLE     Volatile organic compounds produced by endophyte Streptomyces sp.
            WY228 mediate plant growth and salt stress tolerance by activating
            hormonal signaling and anthocyanin biosynthesis,
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 8286721)
  AUTHORS   Qin,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUL-2021) Key lab of biotechnology of medicinal
            plants, Jiangsu Normal University, No. 101 Shanghai Road, Xuzhou
            221116, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Canu v. 1.5
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 100.0x
            Sequencing Technology             :: Oxford Nanopore
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_019287315.1-RS_2024_09_06
            Annotation Date                   :: 09/06/2024 06:02:41
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,303
            CDSs (total)                      :: 7,213
            Genes (coding)                    :: 7,059
            CDSs (with protein)               :: 7,059
            Genes (RNA)                       :: 90
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 155
            CDSs (without protein)            :: 154
            Pseudo Genes (ambiguous residues) :: 0 of 155
            Pseudo Genes (frameshifted)       :: 83 of 155
            Pseudo Genes (incomplete)         :: 99 of 155
            Pseudo Genes (internal stop)      :: 10 of 155
            Pseudo Genes (multiple problems)  :: 36 of 155
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 03:35:29
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 6602429
            Orig. end                         :: 6615429
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP079114.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..13000
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="hydrogen-cyanide"
                     /region_number="26"
                     /rules="(Fer2_4 and cds(Pyr_redox_2 and Fer2_BFD) and DAO)"
                     /tool="antismash"
     cand_cluster    1..13000
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(Fer2_4 and cds(Pyr_redox_2 and Fer2_BFD)
                     and DAO)"
                     /kind="single"
                     /product="hydrogen-cyanide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..13000
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[5000:8000](+)"
                     /cutoff="5000"
                     /detection_rule="(Fer2_4 and cds(Pyr_redox_2 and Fer2_BFD)
                     and DAO)"
                     /neighbourhood="5000"
                     /product="hydrogen-cyanide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..8000
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="(Fer2_4 and cds(Pyr_redox_2 and Fer2_BFD)
                     and DAO)"
                     /neighbourhood="5000"
                     /product="hydrogen-cyanide"
                     /protocluster_number="1"
     gene            264..1250
                     /locus_tag="KV381_RS28915"
                     /old_locus_tag="KV381_28915"
     CDS             264..1250
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006128201.1"
                     /locus_tag="KV381_RS28915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_28915"
                     /product="hypothetical protein"
                     /protein_id="WP_373461123.1"
                     /transl_table=11
                     /translation="MSLSHTYMALMTDLRIVITGWSHLLRTFIALGLLLALVGCQADTS
                     PTPEDSVPRARELVDLRSRVLGYTAKLRADAPYSPPGKAQRVRLAKAVGSLLSGDAQEA
                     ERQLAPLGLGLTRLTDTDSGRRYDEIAATGPGRSARWGRLYLNADSTVRWNAQVPHPVS
                     DRDTEVLGVRLLEQNPGGALVLAGAHRRAGENDAADVAHREDSAFHTIVVELQKRGVPG
                     VQLHGFTDSADRPYDAVVSTGAVETAPAEVVAMADRMDDKGLRVCRAWAARCPLEGRAN
                     VQGRSADREHARFVHVELARHARADDGRDTEEAVDALGGLVAGWNGG"
     gene            complement(1413..2066)
                     /locus_tag="KV381_RS28920"
                     /old_locus_tag="KV381_28920"
     CDS             complement(1413..2066)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003965675.1"
                     /locus_tag="KV381_RS28920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_28920"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_030631535.1"
                     /transl_table=11
                     /translation="MPTTKTLREGSAHKRAAILSAARELFLADGFDRSSVDAVAARAEV
                     SKRTVYDYFGDKRTLLRAVVDSVGQSLITTIRRTLDDTLTELTDGDELEERLVTFAMRI
                     ATDMLGSAEYATLQRLLRTESDHLPHRDYNSMADTPDEAIADRFAAFAEAGLLDAPDPR
                     LAADQFLALTFGVALDRLGSANAAQDARVRPLVVEGVRTFLRAYRSGRGPSGTA"
     misc_feature    complement(2187..2201)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.38"
                     /tool="antismash"
     gene            2201..3598
                     /locus_tag="KV381_RS28925"
                     /old_locus_tag="KV381_28925"
     CDS             2201..3598
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1005: Drug
                     resistance transporter, EmrB/QacA"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018957042.1"
                     /locus_tag="KV381_RS28925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_28925"
                     /product="MFS transporter"
                     /protein_id="WP_103538685.1"
                     /transl_table=11
                     /translation="MTTTQTPPLRVGKAAVGALGALAVATGALESVVTPTLPLLQRELE
                     LSPSEGALLSIVLLVTGALVTPIAGKLGDRHGGKQIMVRLMTVVCAGGLVSALAPNLPV
                     LLLGQILQGAMVGALPLSFILVREHLPAGEAKVAVGVVSGLFVGGGMAGTLAAGPVAEG
                     LSRHWMFALPTFAVIGATVLVNRVLPHDPPRRSDGAGVDLPGLVLLSGTLVTLMLVLAL
                     APEIAARPLVLGALAVLLAAFVTGWVAVERRAASPMVDLRMLSRPAVWKSCVLTFVICV
                     GTSMAVHLVPQLLGLSADGYGFGASATQIGLFLLPGAVAASLAGPVSGFGARRYGSRAV
                     VTAGIVIMSAALIALAAAHDEVGHLVIGKLLIALANGLCVTALVTGTATSVDRGDTGIA
                     TGLVLVTRVIGFAVGVQISGAILTAGTPTGSNIPAESAFVTGFVLAGAVTALSLLVVRT
                     LNKGDQE"
     misc_feature    2414..2416
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            3595..4818
                     /locus_tag="KV381_RS28930"
                     /old_locus_tag="KV381_28930"
     CDS             3595..4818
                     /GO_function="GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1087: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006344964.1"
                     /locus_tag="KV381_RS28930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_28930"
                     /product="FAD-dependent monooxygenase"
                     /protein_id="WP_086779265.1"
                     /transl_table=11
                     /translation="MTRTALSQGAPAVRRRTVLISGASIAGPALAFWLNRYGCAVTVVE
                     KAGALRGGGYPIDVRGTALDVVRRMGILPRLRDAHIDLRRLTFLDEDGGEVASVDPNAV
                     TGGVAGEDLEVRRGALAGALYAAVRDDVEFLFDDSIDTLDQHRHGVDVTFRGGGSRTFD
                     LVVGADGLHSRTRELVFGPEEGFHRYLGYCFAGFTVRNTFGLVREATMWNSPGRAAVLY
                     AVEDGDEVHALLNFARPEPPSGAFRDPEAQRDLVAEVFAGAGWEVPGLLAALREAEDLF
                     FDAVGQIRMPRWSDNRVALVGDAAYAPSFLTGQGSSLALVGAYMLAGSLAAERDHTAGF
                     AAYERDTRAFVTLNQDRVGEGDAVLFPATARALEQRNAMLRGLVAPPPAEGRPAHSALV
                     LPEFTPVV"
     misc_feature    4932..4952
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 21.36"
                     /tool="antismash"
     misc_feature    complement(4933..4953)
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 19.61"
                     /tool="antismash"
     misc_feature    complement(4955..4965)
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: strong, score: 22.4"
                     /tool="antismash"
     gene            5001..6161
                     /locus_tag="KV381_RS28935"
                     /old_locus_tag="KV381_28935"
     CDS             5001..6161
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hydrogen-cyanide: DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1103: FAD dependent oxidoreductase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007454561.1"
                     /locus_tag="KV381_RS28935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_28935"
                     /product="FAD-binding oxidoreductase"
                     /protein_id="WP_218786688.1"
                     /sec_met_domain="DAO (E-value: 2.1e-64, bitscore: 217.1,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKVVVVGAGIVGAACAFHAVAAGLDVTVLDRGPVGAGTTSRGEGN
                     ILLSDKEPGPELELARLSRGLWGEVAAELGPESVEFETKGGLVVASTPEALTALHAFAA
                     RQAESGVRTEPVERPGDLEPHIAPGLPGGVHYPQDAQVQPVLAAAGLLRAAVRRGARTH
                     TGEAVAAVTGTGGRITGVRTAGGSVLAADAVVNAAGTWGGEVGRRLGAPVEILPRRGFV
                     LVTEPLPPMIRRKVYSADYVANVASSDAGLETSCVVEGTRAGTILIGASRERVGFDTAM
                     NPAVVTALAARACRLFPFLRGVHLIRAYRGFRPYCPDHLPVVGPDPRVPGVVHACGHEG
                     AGIGLAPATGALVTAQLLGKPWRGADPAAHTGLLPDRFLTTGGAPK"
     gene            6188..6448
                     /locus_tag="KV381_RS28940"
                     /old_locus_tag="KV381_28940"
     CDS             6188..6448
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hydrogen-cyanide: Fer2_4"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007454563.1"
                     /locus_tag="KV381_RS28940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_28940"
                     /product="(2Fe-2S)-binding protein"
                     /protein_id="WP_218787317.1"
                     /sec_met_domain="Fer2_4 (E-value: 9.7e-25, bitscore: 85.2,
                     seeds: 114, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAETAFTVDGEPLAFVPGQTLAAALVASGRVAWRTTRGGQRPRGI
                     FCGIGVCFDCLVTVDGRGGQRACLVLARPGMAVTTGEDGDE"
     gene            6441..8000
                     /locus_tag="KV381_RS28945"
                     /old_locus_tag="KV381_28945"
     CDS             6441..8000
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hydrogen-cyanide: Pyr_redox_2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hydrogen-cyanide: Fer2_BFD"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1176: alkyl hydroperoxide reductase subunit"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011030798.1"
                     /locus_tag="KV381_RS28945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_28945"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_218786689.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 2.2e-18, bitscore:
                     65.2, seeds: 64, tool: rule-based-clusters)"
                     /sec_met_domain="Fer2_BFD (E-value: 6.8e-11, bitscore:
                     41.1, seeds: 211, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSESGDLLVTGEPHDLVVVGAGPAGMAAAATALDGGLRVVLVDAG
                     AALGGQFWRHPPPLAQEAVPTADLHHGLGVYRELCARLAAHERTGRLALLLNHPVWTTA
                     REDDGFTVHAVDRSRAPEERTVVLRAPALLVATGAYDRQLPFPGWDLPGVLTAGGLQAL
                     LKGGGAVAGRRVVLGGTGPFLLPVAAALAVRGAEVVAVCEAAAPSAWLRHPAALLRNPA
                     KWAEAARYAGTLARHRIPVRTRTAIIGAEAGAGAGAGGQAGVGGAAEGRVASVLTAALD
                     ADGNPLPGTERRIAADTVGVGWGFVPQVDLLLPLGCDLADAGDGTMAAAVDDGQRTTVP
                     GLYTAGETCGVGGAALAVSEGRVAAVSILTDLSAPGLPNSRRLAAERRTVTRHRAFARA
                     MARAHPLPPAWPAWLTDDTPVCRCEEVTAGAVRSARADDAAADHRQVKQLTRAGMGWCQ
                     GRMCGPAVHCLVARDQPYAPAERLIATPVTLGALADADASPPGPPLDPAPDLDPAPASD
                     PT"
     gene            8010..8918
                     /locus_tag="KV381_RS28950"
                     /old_locus_tag="KV381_28950"
     CDS             8010..8918
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007454567.1"
                     /locus_tag="KV381_RS28950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_28950"
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="WP_030079942.1"
                     /transl_table=11
                     /translation="MDRTSPRPRTPWHGVIVATGLPFGQDLAVDHGAYGENVAWLAEQG
                     LHGVAPNGSLGEYQTLTYEERDRVVETAVAHAPEGFTVMPGVGAYGAIEARRHALFARD
                     AGCQAVMCLPPNAYRADDRAVLEHYAMVASAGLPVTAYNNPIDTKVDLRPELLAKLHAE
                     GFIVGVKEFSGDVRRCYAINELAPGLDLIIGTDDTVLEVAVAGAKGWVAGYPQVFPRAC
                     LDLYNASLAGDLDTALPLYRRLHSVLRWDSRTEFVQAIKLGQDMIGRTGGVCRPPRQAL
                     DPETEAVVRSATQALIDAGVN"
     gene            8920..9921
                     /locus_tag="KV381_RS28955"
                     /old_locus_tag="KV381_28955"
     CDS             8920..9921
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012378674.1"
                     /locus_tag="KV381_RS28955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_28955"
                     /product="proline racemase family protein"
                     /protein_id="WP_218786690.1"
                     /transl_table=11
                     /translation="MRSKVCYHAVDSHTEGMPTRVITGGVGVLPGTTMAERRQRFMAER
                     DGLRTLLMCEPRGHASMSGAILQPPTRPDADFGVLFIEVSGCLPMCGHGTIGVATVLVE
                     TGMVEAVEPETLIRLDTPAGLVTARVAVRDGRAESVTLENVASYSHALDQVVEVAGFGA
                     VRYDMAYGGNFYAVVRTDDLGIPFDRSEKGRLLDAGLAVMAAINEQNPVVHPENPAIDV
                     CHHVYLEAPGSTAEHSRHAMAIHPGWFDRSPCGTGTSARMAQLHARGLLKAGQDFVNES
                     FIGSRFTGRILGEGTVGDRPAVLPSVTGRAWITGTAQYLLDPTDPYPTGFTV"
     misc_feature    8926..8941
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 19.49"
                     /tool="antismash"
     gene            10109..11044
                     /locus_tag="KV381_RS28960"
                     /old_locus_tag="KV381_28960"
     CDS             10109..11044
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1158: ornithine cyclodeaminase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018957033.1"
                     /locus_tag="KV381_RS28960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_28960"
                     /product="ornithine cyclodeaminase family protein"
                     /protein_id="WP_218786691.1"
                     /transl_table=11
                     /translation="MSLDAADVSALGPVAAVAAVRDALAGGLDPDGDVPRAVVPLAHGQ
                     GLLMPSEHGGWYGVKVATVAPGNTARGLRRINATYLLHDSATLTPVALLDGVALTTLRT
                     PAVSVAVGLERLRALAAGCGGEGRGLRLVVFGAGPQGEGHVATVRAHVPVADVAVVTRR
                     GGPVPGWADRHLAADDGGVADLVRWAEAVVTATSARRPVVDGRLVRDDAVVLAVGSHEP
                     DVRELDSVLMGRATVVVESRGIALREAGDVVLAIREGTLAPDGLVTPADLSGARADRPL
                     VVKTCGAGWQDLVVAVAAYRRKTGTVGRRG"
     gene            complement(11225..11935)
                     /locus_tag="KV381_RS28965"
                     /old_locus_tag="KV381_28965"
     CDS             complement(11225..11935)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1071: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006128212.1"
                     /locus_tag="KV381_RS28965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_28965"
                     /product="GntR family transcriptional regulator"
                     /protein_id="WP_030079936.1"
                     /transl_table=11
                     /translation="MSELKSRKLISVQEHLRDQVANALRAALIAGELQPGVIYSAPTLA
                     AEYGVSATPVREAMLDLAREGLVEAVRNKGFRVTELSERDLDEYTEIRALIEIPTIGRV
                     TRTASREQLEALRPVAEEIVTAAQGGDLIAYLESDRRFHLELLALAGNARLVETVADLR
                     KRSRLYGLTDLSEEGSLVSSAREHTALLDIMIAGDAEAAEEHMRGHLAHVRTLWAARKR
                     EAERAAPTRRLGAR"
     misc_feature    11963..11979
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 16.35"
                     /tool="antismash"
     misc_feature    11967..11977
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 20.42"
                     /tool="antismash"
     misc_feature    12091..12101
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.94"
                     /tool="antismash"
ORIGIN
        1 ggccttgctg atcacgggct tcaccccggc gagcagcggt ccgaagtcca gtccggcctc
       61 tccgcgaccg ctctccttcg cgtccttcgc ggcctgttcg accagctccg gatggatgag
      121 gacatcgccg gccgcggcta cggtgaagct gcgcccaccg gccttggcct ggggctgcgc
      181 cggcttggtg ccgcacgaca cggtgaggcc gacggccatc gccaggaggg tcagcgagcg
      241 acccataccg agagaattac ggattgtcac taagtcatac ttacatggcc ctcatgaccg
      301 accttcggat tgtcatcacg ggatggtcac atttgctgcg cactttcatc gccctgggtt
      361 tgctcctggc tctggtcggc tgccaggccg atacgtcccc gaccccggaa gattccgttc
      421 cgcgcgcccg ggaactggtc gacctgcgca gccgcgtgct cgggtacacg gcgaagctcc
      481 gtgccgatgc tccctacagt ccgccgggca aggcgcagcg cgtacggctg gcgaaggccg
      541 tcgggagcct gctgtcgggt gacgcccagg aggcggagcg gcagctcgcc ccgctcggcc
      601 tcggcctcac ccgcctcacc gacaccgact cgggccgccg ttacgacgag atcgccgcca
      661 ccgggccggg ccggagtgcc cgttggggcc ggctctacct gaacgccgac tccaccgtcc
      721 gctggaacgc ccaggtcccg caccctgtct ccgaccgcga caccgaggtc ctcggagtcc
      781 ggctcctgga gcagaacccc ggcggcgctc tcgttctggc gggagcccac cgccgggccg
      841 gcgagaacga cgcggccgat gtcgcccacc gcgaggacag cgccttccac acgatcgtcg
      901 tggagctgca gaagcgcggg gtgcccggcg tccagctgca cggattcacc gactccgccg
      961 accgccccta cgacgccgtc gtctccaccg gcgccgtcga gacggcgccc gccgaggtgg
     1021 tggcgatggc cgaccgcatg gacgacaagg gcctgcgggt ctgccgggcc tgggcggcac
     1081 gctgcccgct ggagggccgg gccaacgtcc agggccgctc ggcggaccgc gaacacgccc
     1141 gcttcgtcca cgtcgagctg gcccgccacg cccgcgcgga cgacggacgc gacaccgagg
     1201 aggccgtcga cgccctgggc gggctggtcg cggggtggaa cggcggctag ggggtgccgt
     1261 actgccgtct gccgggagac acccggccgc ccttcgggcg acgacggcag ttagacgaca
     1321 ggccctaggg gcgcgggcgt tcggagcggg cgtcttccaa gggcgtggcc gcgggtgggt
     1381 gcctgcgtcg gagcccggcc cgccggccgg tgtcaggcgg tgccgctcgg gccccggccg
     1441 gaacggtagg cccgcaggaa ggtccgtacc ccctcgacga ccagcggccg tacgcgggcg
     1501 tcctgcgcgg cgttcgcgga gccgagccgg tccagggcga cgccgaaggt cagcgcgagg
     1561 aactggtcgg cggccagccg ggggtcgggg gcgtcgagca ggccggcctc ggcgaaggcg
     1621 gcgaaccggt cggcgatggc ctcgtcgggg gtgtcggcca tcgagttgta gtcccggtgc
     1681 ggcagatggt ccgactccgt cctgaggagc cgctgcagcg tggcgtactc cgccgagccg
     1741 agcatgtcgg tcgcgatgcg catcgcgaac gtgaccaggc gctcctccag ctcgtcgccg
     1801 tccgtgagct cggtgagggt gtcgtccagc gtgcgccgga tcgtggtgat cagcgactgg
     1861 ccgacggagt cgacgacggc ccgcaacagc gtccgcttgt cgccgaagta gtcgtagacc
     1921 gtccgcttgg acacctcggc ccgggcggcg accgcgtcca cgctggaccg gtcgaagccg
     1981 tcggcgagaa acagctcccg ggccgccgag aggatggcgg cccgcttgtg tgcggatccc
     2041 tcgcgcagcg tcttggtggt cggcatggac tcatcctaac cgttctacac tgcacggtgt
     2101 agtgtagttc tggcccggtg cgcgccgtac gcgtcctccg tacgcgtcca tccgtgcgtg
     2161 gccgactcct tctcgccggg ccgtgacgga aaggatgtcc atgaccacga cccagactcc
     2221 gccgctccgt gtcgggaagg ccgccgtcgg agccctcggc gcgctggcgg tggccaccgg
     2281 cgcactggaa tcggtggtga cgccgacgct cccgctcctg cagcgcgagc tcgaactgag
     2341 cccctccgaa ggggcgttgc tcagcatcgt gctcctcgtc accggcgcgc tcgtcacacc
     2401 gatcgcggga aagttaggcg accgccacgg cggaaaacag atcatggtcc ggctgatgac
     2461 ggtggtctgc gccgggggtc tggtgtccgc cctggcgccg aacctgccgg tgctgctgct
     2521 cggtcagatc ctccaggggg cgatggtggg cgcgttgccc ctgtcgttca tcctggtgcg
     2581 cgaacacctc ccggcgggcg aggccaaggt ggccgtcgga gtggtcagcg ggctgttcgt
     2641 cggcggcggg atggcgggga cgctggcggc cgggccggtc gccgaagggc tgtcccggca
     2701 ctggatgttc gcgctgccga cgttcgcggt catcggcgcc accgtgctgg tgaaccgggt
     2761 gctgccgcac gatccgccgc gccgctcgga cggcgccggc gtcgacctgc ccggcctggt
     2821 tctcctcagc ggcacgctgg tcacgctcat gctcgtcctc gcgctggcgc ccgagatcgc
     2881 cgcacggcct ctcgtactcg gcgccctggc cgtgctgctg gccgccttcg tgaccggatg
     2941 ggtggccgtc gagcgccggg cggcctcgcc gatggtcgat ctgcgcatgc tgagccgccc
     3001 cgccgtgtgg aagtcctgtg tgctgacgtt cgtgatctgc gtcggcacct cgatggcggt
     3061 ccatctcgtc ccgcagctcc tcgggctgtc cgccgacgga tacggcttcg gggcgagcgc
     3121 cacgcagatc ggcctcttcc tgctgcccgg cgccgtggcc gcctcgctgg ccgggccggt
     3181 cagcgggttc ggggcacggc ggtacggctc gcgtgccgtg gtcaccgccg ggatcgtcat
     3241 catgagcgcc gccctgatcg ccctggcggc cgcgcacgac gaggtcgggc acctggtcat
     3301 tggcaagctg ctgatcgcgc tcgccaacgg cctgtgcgtg acggcgttgg tgaccggcac
     3361 cgccacctcc gtcgaccgcg gtgacaccgg catcgccacc ggcctggtcc tggtgacgcg
     3421 cgtgatcggc ttcgccgtgg gcgtgcagat cagcggcgcg atcctcaccg ccggaacccc
     3481 caccggatcg aacatcccgg ccgaatcggc cttcgtcacc ggcttcgtcc tggccggcgc
     3541 cgtcacggcg ctgtccctgc tcgtcgtccg caccctgaac aaaggagacc aggaatgacc
     3601 cgcaccgctc tgtcccaggg agcccccgcc gtgcggaggc gcacggtcct gatctccggg
     3661 gccagtatcg cggggcccgc cctcgcgttc tggctgaacc gctacggatg cgcggtcacc
     3721 gtggtcgaga aggcgggcgc gctccgcggc ggcggctatc ccatcgacgt acggggcacc
     3781 gcgctcgacg tcgtccggag gatgggcatc ctgccgcgcc tgcgcgacgc gcacatcgac
     3841 ctgcgccggc tgaccttcct cgacgaggac ggcggcgagg tggcctcggt cgacccgaac
     3901 gccgtcaccg gcggagtcgc gggggaggac ctggaggtac ggcgcggggc gctggccggg
     3961 gctctgtacg cggcggtccg tgacgacgtg gagttcctgt tcgacgactc catcgacacc
     4021 ctcgaccagc accgccacgg ggtcgacgtc accttccgcg gtggcggcag ccgtacgttc
     4081 gacctcgtgg tcggggcgga cgggctccac tcacgtaccc gcgagctcgt gttcggcccc
     4141 gaggaggggt tccaccggta cctcggctac tgcttcgccg gattcaccgt gcgcaacacc
     4201 ttcgggctcg ttcgcgaggc cacgatgtgg aactccccgg gccgggccgc cgtgttgtac
     4261 gccgtggagg acggcgacga ggtccacgcg ctcctcaact tcgcccgccc cgaaccgccg
     4321 tccggcgcgt tccgcgaccc ggaggcccaa cgcgacctgg tcgccgaggt gttcgccggg
     4381 gccggctggg aggtcccggg cctgctcgcc gccctgcgcg aggcggagga cctgttcttc
     4441 gacgcggtcg gccagatccg catgccccgc tggtccgaca acagggtcgc cctggtcggc
     4501 gacgccgcgt acgcgccctc gttcctcacc ggacagggct ccagcctcgc gctcgtcggc
     4561 gcgtacatgc tggccggctc cctggcggcc gaacgggacc acaccgcggg cttcgccgcc
     4621 tacgagcggg acacccgtgc gttcgtgacg ctcaaccagg accgggtcgg cgagggggac
     4681 gccgtgctct tcccggccac cgcccgggcc ctggagcagc gcaacgccat gctgcgcggt
     4741 cttgtcgcgc cgcccccggc ggagggccgg cctgctcatt cggcgctggt cctaccggag
     4801 ttcaccccgg tggtgtgaga ccggatgctg tgggaccggg cccggccggg cgcgccgggt
     4861 gtccggcgcg ccgtcgtcgg gtgcccgggt gaaagtcacc ggggcggcgg cgttgtcctc
     4921 gggtcgtccg gatgtatagc ctaggcaatg gcatgtgaca ttgcactagc ggcggccgtg
     4981 cgggcgccaa aggggtggcc atgaaagtcg tagtcgtcgg cgcgggcatc gtgggcgccg
     5041 cctgcgcgtt ccacgccgtc gcggccggcc tcgacgtcac ggtgctcgac cggggccctg
     5101 tcggcgcggg cacgaccagt cggggcgagg gcaacatcct cctctccgac aaggagccgg
     5161 ggcccgaact ggaactggcc cggctcagcc gcggactgtg gggcgaggtc gccgcggaac
     5221 tcggcccgga gagcgtcgag ttcgagacca agggcggcct ggtcgtcgcg agcacgcccg
     5281 aagccctcac cgccctgcac gcgttcgccg cgcgccaggc ggagtccggc gtccgtaccg
     5341 aacccgtcga gcgccccggc gacctcgaac cgcacatcgc acccggtctg cccggcggcg
     5401 tccactatcc gcaggacgcc caggtgcagc ccgttctcgc cgcggccggg ctgctgcgcg
     5461 ccgccgtgcg ccgcggagcc cgtacgcaca ccggcgaggc cgtcgccgcc gtcaccggaa
     5521 ccggcgggcg gatcaccgga gttcgcacgg ccggcggttc ggtactggcc gccgacgccg
     5581 tggtcaacgc ggccggaacg tggggcggcg aggtcggccg ccggctcggc gcacccgtcg
     5641 agatcctgcc gcgccggggc ttcgtcctcg tcaccgagcc gctgccgccg atgatccggc
     5701 gcaaggtcta ctccgccgac tacgtcgcca acgtcgcctc cagcgacgcg ggcctggaga
     5761 cctcgtgcgt cgtcgagggc acccgcgccg gcaccatcct gatcggcgcc agccgggaac
     5821 gcgtcggctt cgacaccgcg atgaacccgg ccgtggtgac cgcgctcgcg gcccgggcgt
     5881 gccgcctctt cccgtttctg cgtggcgtcc acctgatccg cgcctaccgg ggcttccggc
     5941 cgtactgccc ggaccatctg ccggtggtcg gaccggaccc ccgcgtcccc ggcgtcgtcc
     6001 acgcgtgcgg ccacgagggc gccggtatcg gcctggcccc cgcgaccggc gccctggtca
     6061 ccgcccagct gctcggcaag ccctggcgcg gcgccgatcc ggccgcccac accggcctgc
     6121 tgcccgaccg attcctcacc accggaggtg cgccgaagtg accgaagtga ccgcagagtc
     6181 ggcagagatg gcggagaccg cgttcaccgt ggacggcgag ccgctggcgt tcgtccccgg
     6241 acagaccctg gccgccgcgc tcgtcgcctc gggccgggtc gcctggcgga ccacccgggg
     6301 cgggcagcgg ccccggggga tcttctgcgg gatcggcgtc tgcttcgact gcctggtgac
     6361 cgtcgacggc aggggcggac agcgcgcctg tctggtcctg gcccgtccgg gcatggccgt
     6421 cacgaccggg gaggacggcg atgagtgagt ccggcgacct cctggtgacg ggtgagcccc
     6481 atgacctcgt ggtggtgggc gcgggcccgg ccggtatggc cgccgccgcc accgccctgg
     6541 acggcggact gcgggtcgtc ctcgtcgacg cgggggccgc tctcggcggc cagttctggc
     6601 gccacccacc gcccctggcg caggaggccg tgccgaccgc ggacctccac cacggcctgg
     6661 gcgtctaccg ggagttgtgc gccaggctgg ccgcccacga gcgcaccggc cggctcgcgc
     6721 tgctgctgaa ccacccggtg tggaccacgg cccgtgagga cgacggattc accgtccacg
     6781 cggtggaccg gagccgggcg ccggaggagc ggaccgtcgt gctgcgcgcc ccggccctgc
     6841 tggtggcgac cggcgcctac gaccgccaac tcccctttcc cggctgggac ctgcccggtg
     6901 tgctcaccgc cggagggctt caggcgctgc tcaagggcgg gggagcggtg gccggccgcc
     6961 gggtggtcct cggcggtacg ggccccttcc tgctgcccgt cgcggcggct ctcgccgtcc
     7021 gcggggccga ggtcgtcgcg gtgtgcgagg cggcggcgcc ctcggcctgg ctgcgccacc
     7081 ccgcggccct gctccgcaac cccgccaagt gggccgaggc cgcccggtac gcgggcaccc
     7141 tcgcccggca ccggatcccg gtccgcaccc gtaccgcgat catcggcgcc gaagcaggag
     7201 caggagcagg agcaggagga caggccggag tcgggggagc agcggagggc cgggtcgcct
     7261 ccgtcctcac cgccgccctg gacgccgacg gcaacccgct gccgggtacg gagcgccgga
     7321 tcgcggccga caccgtgggc gtcggctggg gcttcgtacc ccaggtggac ctcctgctcc
     7381 cgctcggctg cgacctcgcc gacgcgggcg acggcaccat ggccgccgcc gtcgacgacg
     7441 gacagcgcac cacggtgccc gggctctaca cggcggggga gacctgcggg gtgggcgggg
     7501 ccgcgctcgc ggtgagcgag ggccgcgtcg ccgccgtctc gattctcacc gacctctccg
     7561 cgccgggcct gccgaacagc aggcggctcg ccgcggagcg ccggacggtg acccggcacc
     7621 gcgccttcgc ccgggcgatg gcccgggccc acccgctgcc accggcctgg cccgcctggc
     7681 tcaccgacga caccccggtc tgccggtgcg aggaggtcac cgcgggtgcg gtccggtccg
     7741 cccgcgccga tgacgcggcg gccgaccacc ggcaggtcaa acagctgacc cgggccggta
     7801 tgggctggtg ccagggccgg atgtgcgggc ccgccgtgca ctgcctcgtg gcccgcgacc
     7861 agccctacgc ccctgccgag cggctgatcg cgacccccgt caccctcggt gcgctcgccg
     7921 atgccgacgc gtccccaccc ggtccgcccc tcgatcccgc ccccgacctc gaccccgctc
     7981 ccgcctccga tcccacctga ggagttccca tggaccgcac ctccccccgt ccccggacgc
     8041 cctggcacgg cgtcatcgtc gcgaccggcc tccccttcgg ccaggacctc gccgtcgacc
     8101 acggcgccta cggcgagaac gtcgcctggc tcgccgaaca gggcctgcac ggcgtcgccc
     8161 cgaacggctc gctgggcgag taccagaccc tgacgtacga ggaacgcgac cgcgtcgtgg
     8221 agaccgccgt cgcccacgcc cccgagggct tcaccgtgat gccgggcgtc ggggcgtacg
     8281 gcgcgatcga ggcgcggcgg cacgcgctgt tcgccaggga cgccggctgc caggccgtca
     8341 tgtgcctgcc gcccaacgcc taccgggccg acgaccgcgc cgtcctggag cactacgcga
     8401 tggtggcctc cgccggactt cccgtcaccg cctacaacaa ccccatcgac accaaggtcg
     8461 acctgcgccc ggagctgctg gccaaactgc acgccgaggg cttcatcgtg ggcgtgaagg
     8521 agttctccgg agacgtccgc cgctgctacg ccatcaatga actcgccccc ggcctcgacc
     8581 tgatcatcgg caccgacgac accgtcctgg aggtcgccgt cgccggcgcc aagggctggg
     8641 tggccggcta cccccaggtc ttcccgcgcg cctgcctcga cctctacaac gcctcgctgg
     8701 cgggcgatct cgacaccgcg ctgccgctct accgccggct ccactccgta ctgcgctggg
     8761 acagcaggac cgagttcgtc caggcgatca agctcggcca ggacatgatc ggccggaccg
     8821 gcggagtctg ccgcccgccc cggcaggccc tggacccgga gaccgaggcc gtcgtccgct
     8881 ccgccaccca ggccctcatc gacgcggggg tgaactgacg tgcgctcgaa ggtctgttac
     8941 cacgcggtcg actcgcacac cgagggcatg ccgacccggg tgatcaccgg cggggtgggc
     9001 gtactgccgg gcacgaccat ggccgagcgg cggcagcggt tcatggccga acgggacggg
     9061 ctgcgcaccc tgttgatgtg cgagccgcgc gggcacgcgt ccatgtccgg cgcgatcctc
     9121 cagcctccga cccggccgga cgccgacttc ggcgtgctgt tcatcgaggt ctccggctgc
     9181 ctgcccatgt gcggccacgg caccatcggc gtggcgacgg tcctggtgga gacgggcatg
     9241 gtcgaggcgg tcgaaccgga gaccctgatc cgcctcgaca cacccgccgg tctcgtcacc
     9301 gcgcgggtcg ccgtgcgcga cggccgcgcc gagtccgtca ccctggagaa cgtcgcctcc
     9361 tacagccacg cgctggacca ggtggtcgag gtggcgggct tcggcgcggt ccgttacgac
     9421 atggcgtacg gcggcaactt ctacgccgtc gtgcgcaccg acgacctcgg tatccccttc
     9481 gaccggtcgg agaaggggcg gctgctcgac gcgggcctgg ccgtcatggc ggcgatcaac
     9541 gaacagaacc cggtggtcca tccggagaac ccggccatcg acgtctgcca ccacgtctat
     9601 ctggaggccc ccggctcgac cgccgagcac tcgcggcacg ccatggcgat ccaccccgga
     9661 tggttcgacc gctcgccctg cggtacggga accagcgcgc ggatggccca actgcacgcg
     9721 cggggactgc tgaaggccgg gcaggacttc gtcaacgagt ccttcatcgg ctcccgcttc
     9781 accggccgca tcctgggcga aggcacggtc ggcgaccggc ccgccgtcct gccctcggtc
     9841 accggccgcg cctggatcac cggaaccgcg cagtatctgc tcgacccgac ggacccctac
     9901 ccgacaggtt tcaccgtatg agccttcacc gtacgagcgt tcactcttgc gccggaccga
     9961 ccctgaccgg caccgcgtac gccaccggaa ccggccgctt caccgtcgat cccgacgacg
    10021 ccctcgtacc cgacgacgcc ctcgtacccg acgacgccct cgtacccgac gacaccctcg
    10081 tacccgccgg gtccggcctg cgacgacggt gtcgctcgac gcggcggacg tgtccgcgct
    10141 cggtccggtg gccgccgtcg ccgcggtccg ggacgctctg gccggagggc tcgacccgga
    10201 cggtgacgta ccgcgggcgg tggtgccgct ggcgcacggt caggggctgc tcatgccctc
    10261 cgagcacggc ggctggtacg gagtgaaggt cgccaccgtc gcacccggca acaccgcgcg
    10321 cgggctgcgg cggatcaacg ccacctatct gctgcacgac agcgcgaccc tgacaccggt
    10381 ggccctgctg gacggggtgg cgctgacgac cctgcgcacc cccgccgtct cggtcgcggt
    10441 gggcctggag cggctgcgcg cgctcgcggc cgggtgcggg ggcgagggcc gggggttgcg
    10501 gctggtggtg ttcggcgcgg gcccccaggg ggaggggcac gtcgccaccg tacgggccca
    10561 tgtgccggtg gccgatgtcg cggtcgtcac ccggcgcgga ggacccgttc cgggctgggc
    10621 ggaccggcat ctggcggcgg acgacggggg agtggcggac ctggtgcgtt gggcggaggc
    10681 cgtcgtcacg gcgacgtccg cgcgcaggcc ggtggtcgac gggcggctgg tgcgcgacga
    10741 cgcggtggtc ctggcggtcg gctcgcacga gccggacgta cgggagctcg acagcgtgct
    10801 gatggggcgt gccaccgttg tggtggagag ccgtgggatc gccctccggg aggcgggcga
    10861 cgtcgtcctg gcgatccgcg agggcacgct cgccccggac ggcctggtca ccccggcgga
    10921 cctgtccggg gcacgggccg accgcccgct ggtcgtgaag acctgcgggg cgggttggca
    10981 ggacctggtg gtcgcggtcg cggcctaccg gcggaagacg gggacggtgg ggaggcgcgg
    11041 ctgaggtgcg cgccggtgtc tcggcctcaa cgcgcgccgc gcgcggcgga cttcgacgtc
    11101 ggcgcgcgcc acgacgtagg ggccccgctt caacgcccgc cgcccccacc gggcttccgc
    11161 gtcggcgcac gccaccgcat cgggcctccg cctcaacacg gcccgccccc accggacttc
    11221 cgcgtcagcg cgcgccgagc ctgcgggtcg gggcggcgcg ttcggcctcc cgcttccggg
    11281 ccgcccacag ggtccgcaca tgcgcgagat ggccgcgcat gtgctcctcg gccgcctccg
    11341 cgtcccccgc gatcatgatg tccaggagcg ccgtgtgctc ccgcgccgaa ctcaccagcg
    11401 acccttcctc ggacaggtcg gtgagcccgt agagccggga gcgcttgcgc aggtcggcca
    11461 cggtctcgac gaggcgggcg ttcccggcga gggcgagcag ttcgagatgg aagcggcggt
    11521 cggactccag ataggcgatc aggtcgccgc cctgcgcggc cgtcacgatc tcctcggcca
    11581 ccgggcgcag cgcctccaac tgctcgcggg aggcggtgcg ggtcacgcgg ccgatggtgg
    11641 ggatctcgat gagcgcacgg atctcggtgt actcgtccag gtcgcgctcg gagagttcgg
    11701 tgacccggaa gcccttgttg cgcaccgcct cgaccagacc ctcgcgggcc aggtcgagca
    11761 tggcctcgcg gacgggcgtc gccgagacgc cgtactcggc ggcgagggtg ggcgcggagt
    11821 agatcacgcc gggctgaagc tcacccgcta tcagcgcggc ccgcagtgcg ttggccacct
    11881 ggtcgcgcag atgctcctgc accgagatga gtttgcggga cttcagctca ctcatgcgtt
    11941 ccccttcacg atttgtcacc gcaccataca atgtcacgtt gcgcggcgag gcggcaccct
    12001 ccggagggtg gtcgaggggc acggggaccg gtgcgcggtc cgggttcgag gggacacgtt
    12061 tcggtaacgg ggcgacgtac atcttggctg tgcaatttca cattactatg ttacgggtca
    12121 cacgctatgg acgcgggcgg ccgctcggcc gcccggatcg ccgccgagcc ctccggcccg
    12181 gcccacctca ccctttctcc ggcacctccc ggcccggtca ggcccgttcc gctccgccgc
    12241 gtcccccttc ccgtacgagg agtgcaccca tgtcccgtcg cacccgcacg ctgtccgcga
    12301 ccctgagcgc ctcgctcgcc ctggccctgc tgggcgcctg ctctgcacag ggaggtgacg
    12361 accgcggccc ggacgagcgg cagcccgggg tggcgaccgg caccgtcatc ggcggcaccc
    12421 cgaagcgcgg cggcaccctg accgtgctgt ccaatcagga cttcgcccac ctggacccgg
    12481 cccgcaactg ggtcatgccg accatggact tcggcacccg gctgatctac cgcaccctga
    12541 ccaccttccg ggccgcgccc gggaagcggg gcagcgagat cgtccccgac ctcgcgaccg
    12601 acctcggcag atcctccgac ggcggccgca cctggacctt caccctgaag ccgggactcg
    12661 tctacgagga cggcaccccg gtccgcgccc gcgacatcaa gtacaacgtc gagcgctcct
    12721 tcgccccgga cctcgcgggc ggccccgact acgcccagcg ctatctggcc ggcaccgagg
    12781 ggtacgccgg tccgctggac ggcgagcacc tcgactcggt ccgtaccccc gacgaccgga
    12841 ccatcgtctt ctcgctgcgc aggcccgtcg ccgagttctc ctacacggtc acgctgccga
    12901 ccttctctcc cgtgcccgag tcccgggaga agggtgtcca gtacgacctg cggcccttct
    12961 cctccgggcc gtaccgcatc gagagctacg cacgcggcaa
//
