LOCUS       NZ_CP079114            22845 bp    DNA     linear   CON 06-SEP-2024
DEFINITION  Streptomyces sp. WY228 chromosome.
ACCESSION   NZ_CP079114
VERSION     NZ_CP079114.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. WY228
  ORGANISM  Streptomyces sp. WY228
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8286721)
  AUTHORS   Qin,S.
  TITLE     Volatile organic compounds produced by endophyte Streptomyces sp.
            WY228 mediate plant growth and salt stress tolerance by activating
            hormonal signaling and anthocyanin biosynthesis,
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 8286721)
  AUTHORS   Qin,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUL-2021) Key lab of biotechnology of medicinal
            plants, Jiangsu Normal University, No. 101 Shanghai Road, Xuzhou
            221116, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Canu v. 1.5
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 100.0x
            Sequencing Technology             :: Oxford Nanopore
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_019287315.1-RS_2024_09_06
            Annotation Date                   :: 09/06/2024 06:02:41
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,303
            CDSs (total)                      :: 7,213
            Genes (coding)                    :: 7,059
            CDSs (with protein)               :: 7,059
            Genes (RNA)                       :: 90
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 155
            CDSs (without protein)            :: 154
            Pseudo Genes (ambiguous residues) :: 0 of 155
            Pseudo Genes (frameshifted)       :: 83 of 155
            Pseudo Genes (incomplete)         :: 99 of 155
            Pseudo Genes (internal stop)      :: 10 of 155
            Pseudo Genes (multiple problems)  :: 36 of 155
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 03:35:29
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 4742501
            Orig. end                         :: 4765346
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP079114.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22845
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lassopeptide"
                     /region_number="18"
                     /rules="(PF13471 and Asn_synthase or micJ25 or mcjC)"
                     /tool="antismash"
     cand_cluster    1..22845
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /kind="single"
                     /product="lassopeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22845
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12845](+)"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12845
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
     misc_feature    156..170
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 19.14"
                     /tool="antismash"
     misc_feature    complement(606..620)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.9"
                     /tool="antismash"
     misc_feature    719..737
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: weak, score: 23.25"
                     /tool="antismash"
     gene            737..1588
                     /gene="otsB"
                     /locus_tag="KV381_RS20655"
                     /old_locus_tag="KV381_20655"
     CDS             737..1588
                     /EC_number="3.1.3.12"
                     /GO_function="GO:0004805 - trehalose-phosphatase activity
                     [Evidence IEA]"
                     /GO_process="GO:0005992 - trehalose biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="otsB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018958814.1"
                     /locus_tag="KV381_RS20655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_20655"
                     /product="trehalose-phosphatase"
                     /protein_id="WP_030087110.1"
                     /transl_table=11
                     /translation="MGSHPESLPNPTTPAGREGLDAVLARPDRAVVALDFDGTLADIVP
                     DPEQARAHPGTVAALAALAPKVAAVAVITGRPAGVAVRYGGFAGVPGLEHLVVLGHYGA
                     ERWDAVTGTVHAPAPHPGVTAVRAELPGVLHEFGAWNGTWIEEKGQAVAVHTRRAEDPQ
                     AAFESLRGPLGELAARHGLIVEPGRLVLELRPPGMDKGVALAGFVAELDAESVIYAGDD
                     LGDLAAFAAVEKLRSEGPDGIPGLLVCSGSTEVPELAERADLSVPGPAAVVAFLAALAE
                     RI"
     gene            complement(1608..2999)
                     /locus_tag="KV381_RS20660"
                     /old_locus_tag="KV381_20660"
     CDS             complement(1608..2999)
                     /EC_number="2.4.1.15"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006126480.1"
                     /locus_tag="KV381_RS20660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_20660"
                     /product="trehalose-6-phosphate synthase"
                     /protein_id="WP_218785969.1"
                     /transl_table=11
                     /translation="MVSEHTSSSNAQVLVASNRGPVTYTLGEDGTLDSKRGGGGLVSGL
                     SAVDDKLWVCAALGDGDREAVRRGVGEEGVRMLDIDAEVHADAYNGIANSVLWFVHHLL
                     YQTPVEPVFDTEFRRQWAAYETYNRAFAEALAEEAGPGAAVLVQDYHLALVPGMLRELR
                     PDLRIGHFSHTPWAPVDYFRLLPDDIAEQLLRGILGADRAAFLTRRWADAFIGCCTEIL
                     GGTGRTRVGVHGLGADADFLRRRSHEADVDERMAALREQVGEGRKTIVRVDRTELSKNI
                     VRGLHAYRTLLDTRPEWRERVVHIAFAYPSRQDLAVYRDYTAAVQTLATEINAAYGTES
                     WTPVVLHVKDDFARSLAAYRLADVALVNPIRDGMNLVAKEVPVVSDHGCALVLSREAGA
                     YEELGEDAIVVNPYDVTGTAEALHEALTMSGDERSGRTKRLAEAATALPPQQWFLDQLE
                     ALREG"
     gene            complement(3064..4014)
                     /locus_tag="KV381_RS20665"
                     /old_locus_tag="KV381_20665"
     CDS             complement(3064..4014)
                     /EC_number="2.4.1.266"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018511020.1"
                     /locus_tag="KV381_RS20665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_20665"
                     /product="glucosyl-3-phosphoglycerate synthase"
                     /protein_id="WP_030633058.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 2.6e-09,
                     bitscore: 35.9, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLEEVERWLTRRSWSSGDRPLNRLTDARDADPRRTSVSVVLPALN
                     EEATVGAIVATIRRELMEKVRLVDELVVIDSGSTDATAAVARAAGARVVHRDAILPRIP
                     ALPGKGEVLWRSLLVTSGEIVCFVDADLKDFSADFVSGTIGPLLTDPTVQFVKAMYDRP
                     LGDRAGQGGRVTELVARPLLNLHWPQLAGFVQPLGGEYAVRRSLLERLPFPVGYGVELG
                     LLVDALHTVGLDALGQVDVGVRIHRHQDGQALGRMAAAIYRTAQLRLSRGHLVRPALTQ
                     FERGEDGFVPRTHAVDTEERPPMREIAEYAERHAA"
     misc_feature    4040..4060
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 18.9"
                     /tool="antismash"
     regulatory      4168..4295
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /regulatory_class="riboswitch"
     gene            4314..5609
                     /gene="thrC"
                     /locus_tag="KV381_RS20670"
                     /old_locus_tag="KV381_20670"
     CDS             4314..5609
                     /EC_number="4.2.3.1"
                     /GO_function="GO:0004795 - threonine synthase activity
                     [Evidence IEA]"
                     /GO_process="GO:0009088 - threonine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="thrC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PALP"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010056010.1"
                     /locus_tag="KV381_RS20670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_20670"
                     /product="threonine synthase"
                     /protein_id="WP_030633055.1"
                     /sec_met_domain="PALP (E-value: 4.1e-61, bitscore: 205.7,
                     seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAVQTVAGNATTAPVDLGPAAALSCRECGERFELGPLFACASCFG
                     PLEVAYDLPTGSPEELRKRIEAGPDNIWRYAPLLPVPSDVAEKPNINPGFTKLVKADNL
                     ARELGVTGGLYVKDDSGNPTHSFKDRVVAIAVEAARAFGFTTLSCSSTGNLAGAVGAAA
                     ARAGLRSCVFIPHDLEQGKVVMAAVYGGELVGIEGNYDDVNRFCSELIGDPLGEGWGFV
                     NVNLRPYYGEGSKTLAYEICEQLGWRLPDQIVIPIASGSQLTKIDKGLQELIKLGLVED
                     RPYKIFGAQAEGCSPVSAAFKAGHDVVRPQKPNTIAKSLAIGNPADGPYVLDIARRTGG
                     AVEDVTDEQVVDAIKLLARTEGIFGETAGGVTLGVTKKLIEAGVIDPTLTTVVVNTGDG
                     LKTLDAVSATSQATATIKPSLDAFRAAGLGTA"
     gene            5645..5923
                     /locus_tag="KV381_RS20675"
                     /old_locus_tag="KV381_20675"
     CDS             5645..5923
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007265553.1"
                     /locus_tag="KV381_RS20675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_20675"
                     /product="MoaD/ThiS family protein"
                     /protein_id="WP_003967347.1"
                     /transl_table=11
                     /translation="MSVKVRIPTILRTYTGGQAEVPAEGAKLSEVIESLEKDHPGIAAR
                     VLDDQGKLRRFVNVYVNDDDVRFEGGLDAATPDGAGVSIIPAVAGGC"
     gene            6369..6575
                     /locus_tag="KV381_RS20680"
                     /old_locus_tag="KV381_20680"
     CDS             6369..6575
                     /GO_component="GO:0005829 - cytosol [Evidence IEA]"
                     /GO_function="GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA]"
                     /GO_function="GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /GO_function="GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1255: cold-shock
                     DNA-binding domain protein"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003967346.1"
                     /locus_tag="KV381_RS20680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_20680"
                     /product="cold-shock protein"
                     /protein_id="WP_003967346.1"
                     /transl_table=11
                     /translation="MAQGTVKWFNAEKGYGFIAVDGGADVFVHYSAIQMDGYRTLEEGQ
                     RVEFEISQGQKGPQADMVKLAVG"
     misc_feature    complement(6417..6430)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.47"
                     /tool="antismash"
     misc_feature    6774..6789
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 19.7"
                     /tool="antismash"
     misc_feature    complement(6777..6792)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 19.11"
                     /tool="antismash"
     gene            6944..8566
                     /gene="groL"
                     /locus_tag="KV381_RS20685"
                     /old_locus_tag="KV381_20685"
     CDS             6944..8566
                     /GO_function="GO:0140662 - ATP-dependent protein folding
                     chaperone [Evidence IEA]"
                     /GO_process="GO:0042026 - protein refolding [Evidence IEA]"
                     /codon_start=1
                     /gene="groL"
                     /gene_functions="other (smcogs) SMCOG1299: chaperonin
                     GroEL"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006133870.1"
                     /locus_tag="KV381_RS20685"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES; misfolded
                     proteins enter the barrel where they are refolded when
                     GroES binds; 60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES; misfolded
                     proteins enter the barrel where they are refolded when
                     GroES binds; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_20685"
                     /product="chaperonin GroEL"
                     /protein_id="WP_003967345.1"
                     /transl_table=11
                     /translation="MAKIIAFDEEARRGLERGMNQLADAVKVTLGPKGRNVVLEKKWGA
                     PTITNDGVSIAKEIELEDPYEKIGAELVKEVAKKTDDVAGDGTTTATVLAQALVREGLR
                     NVAAGANPMALKRGIEKAVEAVSAALLEQAKDVETKEQIASTASISAADTEIGAKIAEA
                     MDKVGKEGVITVEESQTFGLELELTEGMRFDKGYISAYFATDMERMEASLDDPYILIVN
                     SKIGSVKDLIPLLEKVMQSGKPLLIIAEDVEGEALSTLVVNKIKGTFKSVAVKAPGFGD
                     RRKAMLADIAILTGGTVISEEVGLKLENAGLDLLGRARKVVITKDETTIVDGAGDSDQV
                     QGRVNQIRAEIENSDSDYDREKLQERLAKLAGGVAVIKAGAATEVELKERKHRIEDAVR
                     NAKAAVEEGIVAGGGVALLQASAVFEKLDLTGDEATGANAVKLALEAPLKQIAVNGGLE
                     GGVVVEKVRNLPIGHGLNAATGEYVDMIAEGILDPAKVTRSALQNAASIAALFLTTEAV
                     IADKPEKAGAAAPGGMPGGDMDF"
     gene            8793..9272
                     /locus_tag="KV381_RS20690"
                     /old_locus_tag="KV381_20690"
     CDS             8793..9272
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019762775.1"
                     /locus_tag="KV381_RS20690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_20690"
                     /product="hypothetical protein"
                     /protein_id="WP_256995119.1"
                     /transl_table=11
                     /translation="MAKDWKGASLVLGGAALFVLGLFVVVTGAGLSGALGMRVETFGRI
                     DCDDTRTKKGQTVWHCFGESPVQQRANEAERERVAREALRAHVDGVPRPAETGRTRILF
                     ADHDGRTDPETITATQVFDGGRWYAHSSMVVGYGMIPLLLGAGAAAWGGYRLRGR"
     misc_feature    8820..8822
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    9527..9542
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: medium, score: 23.0"
                     /tool="antismash"
     misc_feature    9724..9738
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 16.93"
                     /tool="antismash"
     gene            9828..9950
                     /locus_tag="KV381_RS20695"
                     /old_locus_tag="KV381_20695"
     CDS             9828..9950
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018511015.1"
                     /locus_tag="KV381_RS20695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_20695"
                     /product="keywimysin-related RiPP"
                     /protein_id="WP_018511015.1"
                     /transl_table=11
                     /translation="MKQQKKAYVKPSLFKQGDFSKKTAGYFYGSYKEYWVRRII"
     CDS_motif       9828..9899
                     /prepeptide="leader"
                     /note="peptide class: lassopeptide"
                     /note="predicted sequence: MKQQKKAYVKPSLFKQGDFSKKTA"
                     /locus_tag="KV381_RS20695_lassopeptide"
                     /aSTool="lassopeptides"
                     /tool="antismash"
     CDS_motif       9900..9950
                     /prepeptide="core"
                     /locus_tag="KV381_RS20695_lassopeptide"
                     /peptide="lassopeptide"
                     /predicted_class="Class II"
                     /score="0.20"
                     /molecular_weight="2082.4"
                     /monoisotopic_mass="2081.0"
                     /core_sequence="GYFYGSYKEYWVRRII"
                     /aSTool="lassopeptides"
                     /tool="antismash"
                     /leader_sequence="MKQQKKAYVKPSLFKQGDFSKKTA"
                     /leader_location="[9827:9899](+)"
     gene            10001..12091
                     /locus_tag="KV381_RS20700"
                     /old_locus_tag="KV381_20700"
     CDS             10001..12091
                     /GO_function="GO:0004066 - asparagine synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA]"
                     /GO_process="GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Asn_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177: asparagine synthase (glutamine-hydrolyzing)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018489032.1"
                     /locus_tag="KV381_RS20700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_20700"
                     /product="asparagine synthase-related protein"
                     /protein_id="WP_218785970.1"
                     /sec_met_domain="Asn_synthase (E-value: 7.7e-23, bitscore:
                     80.4, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPGQLRDYFVVLPDSVAGAAVAGRLPPGAGGGTVVAHASGRPWVL
                     ARPLVRRVSHLRRGDDALVLIGPDRVSDAVLSGLLEGARDRAGLERRLARLPGLHHVIA
                     RLSGQTWIRGTASGLRRIYHARHPEAGTIASDRPAVLARLIGAPLDDGALALRMLDFLP
                     HPLSRRVVWRGVHETGAGYGLALPAAAPGTAAVPGPTEHRWWEPPPAELPLADGAQALG
                     DAIAASVRAHVGGLDRISCELSGGMDSTALTFAARATGPAELALLTVAARDRYSEDETW
                     ARRAVEAAREGGVGARGGEAARGGEATRSGGAARGAGGNRDSNAARTRDAGRKGGDVTG
                     LEHHIIPADDAPYFYAELAATAAELNDEPLPVAPGRARAHLLLSRAHATGSRYHLTGYG
                     GDELFLGLPHAYQDLFHGNPLTAWNHLSGLRHQLGWPFLPTLKALLNRSTFPRWLAGAI
                     TAEPQPVTRTPLLSWGVRQSLRPWFTEHANALIAEEFRAAAERAEPIDPWRGRHVDIDA
                     VRMGARHFQAMEDIGMTIGLPVAAPFYDDRVLEATLAVRLAERISPWRYKPLLVEAMRG
                     VVPDALLARTTKDHMSSDEHQGLRQHASELADLWTGSRLAEHGLVDSRHLLRLAAEPFS
                     PVLVEHSVSSTVAGETWLRTAENAWPTPTPTPTPTPTPTPTPAQSPSLPPHRTSTTSEA
                     TL"
     aSDomain        12088..12333
                     /aSDomain="Stand_Alone_Lasso_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="Stand-alone RRE protein in a lasso peptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_KV381_RS20705_Stand_Alone_Lasso_RRE.1
                     "
                     /evalue="1.30E-26"
                     /identifier="RREFam002.1"
                     /label="KV381_RS20705"
                     /locus_tag="KV381_RS20705"
                     /protein_end="82"
                     /protein_start="0"
                     /score="83.4"
                     /tool="antismash"
                     /translation="MKLRKGIAVTTTEYGGVLLDEKDGSYWQLNDTSIIVVDTLAAGHT
                     PDIAVERILAAFDVERAEAESDVAELTRQLVDAKILR"
     gene            12088..12339
                     /locus_tag="KV381_RS20705"
                     /old_locus_tag="KV381_20705"
     CDS             12088..12339
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006126488.1"
                     /locus_tag="KV381_RS20705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_20705"
                     /product="lasso peptide biosynthesis PqqD family chaperone"
                     /protein_id="WP_030087127.1"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 3.3e-24,
                     bitscore: 83.4, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 9.6e-12, bitscore: 43.7,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKLRKGIAVTTTEYGGVLLDEKDGSYWQLNDTSIIVVDTLAAGHT
                     PDIAVERILAAFDVERAEAESDVAELTRQLVDAKILRP"
     gene            12336..12845
                     /locus_tag="KV381_RS20710"
                     /old_locus_tag="KV381_20710"
     CDS             12336..12845
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: PF13471"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010071618.1"
                     /locus_tag="KV381_RS20710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_20710"
                     /product="lasso peptide biosynthesis B2 protein"
                     /protein_id="WP_218785971.1"
                     /sec_met_domain="PF13471 (E-value: 2.2e-23, bitscore: 81.2,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTEMTMPRRGAGAGGVRLRTAIVAAFVLARLKPGRLRRVLARCA
                     RDARPASYAETMEVLEAVVATSRRCASRYGCLPRSVAVALACRMSGVWPDWCAGVRSAP
                     PFAPHAWLQAEGRTVGEQAEPADLRPLMVVTAAAVTAGGGVRDERGVGDGGGGSESRGG
                     GGRQRA"
     gene            12775..14922
                     /locus_tag="KV381_RS20715"
                     /old_locus_tag="KV381_20715"
     CDS             12775..14922
                     /EC_number="7.-.-.-"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012379740.1"
                     /locus_tag="KV381_RS20715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_20715"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_256995120.1"
                     /transl_table=11
                     /translation="MSAVSGTAGAEARAGAEAAGSGPEDAGTPAAGPAGEPVGPGQTAG
                     VPVGPGQPTEEAAEPEQPTEEAAEPERPTGEAAEPERPTGEAAEPERPTGEAAGPERPT
                     GEAVGPERPTGEAAAPEAPAGGSPADTTGNPAQGKSGPSPLRLLLARVRPHRGVLIRAG
                     LLSLTGSAAGLAMPLMAKYAVDAFAADRSPVAPLVALTALVLAGACISAYGRYLMARTG
                     EGVVLRARDQLVGRIMRLKVPAVDRLTPGDLQSRVTSDTTLLRTVLSSGLVESFNSVLM
                     LLGTVAFMAYMDVTLLGVTLVVIVGIGAVTALLMPRIQRAQLRAQESVGAMGAALDRVL
                     QAFRTVKASGAEERETAAVAEAARHAHDRGVSVAKWSSVSDVTMMMSIQLAFLAVLGVG
                     GARVASGSLEISSLIAFLLYLFYLMGPIGGLVEGWTGLQSGLAAVRRIDEVESLPGETS
                     TGSGAMEPEGGPLGVAFQDVTFGYGDERAPAHKGVTFDVPAGGLVALVGPSGAGKSTVF
                     SLLERFYDHDGGTITVGGRDIRDWPLAELRASLAYVEQDAPVLAGTLRENLLFAAPEAE
                     EKELTAAVARTRLDALVDRLPDGLDTAVGHRGVTLSGGERQRIAIARALLRRPRLLLLD
                     EVTSQLDAVNEQALRDVILEMAEQATVLVIAHRLSTVRHADRIVVLEEGRVRTAGTHEE
                     LIAGDDLYRELATTQLAAEVA"
     gene            14922..15311
                     /locus_tag="KV381_RS36610"
     CDS             14922..15311
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="KV381_RS36610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_256995121.1"
                     /transl_table=11
                     /translation="MAGRRRRDDGSAANAMMGDKGTGTGTIESPETPATPATPATPATP
                     ATPATPATPATLYGPVSLGFGVIALIAAFFLGLFALLAGSLAITFGVLGLIGGYNRPQC
                     LAGLVLGAVGVLHPLSFLFAFTGGF"
     gene            complement(15337..15924)
                     /locus_tag="KV381_RS20725"
                     /old_locus_tag="KV381_20725"
     CDS             complement(15337..15924)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019762767.1"
                     /locus_tag="KV381_RS20725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_20725"
                     /product="Uma2 family endonuclease"
                     /protein_id="WP_218785972.1"
                     /transl_table=11
                     /translation="MTPSSADHAPHAQMSVEEFEQLARTAPETVTLELINGKLEVKPVP
                     DGDHDEIIMWVAMQCMQQQPELRLYRERGLRIGGYRNGRARPDGTLARAGRFAGDGEWS
                     NPDRVLMTVEVTSHDHDTDHRDRTEKRDGYAAAGIPVYLLIDRDHDALVVYSEPENGRY
                     RQRTTYEYGKAAALPHPVDITLDTEELKDYAR"
     gene            complement(15981..16799)
                     /locus_tag="KV381_RS20730"
                     /old_locus_tag="KV381_20730"
     CDS             complement(15981..16799)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018958801.1"
                     /locus_tag="KV381_RS20730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_20730"
                     /product="hypothetical protein"
                     /protein_id="WP_218785973.1"
                     /transl_table=11
                     /translation="MANPGYGKRSAPGERPRTDRDFAHLLPRDASVAAYIDRLPDGSDI
                     SVKTLAKHLPYGQCALRTTLNRLQDAGHLRRGSECVITDEVMLWVTRTFFSRTAREDAW
                     WNAYTRGDAPPDEPQRPTRSRAFILLAALGRTAPALTLSAADCVRLEPQVGEWIARGAT
                     EAELLHALTSGLPSPVHCAARLVERRLRDKLPPEPVLPGPRTVLRTLECGKCGVPGSPE
                     ALLGGLCRPCRGPSPEPPVGPPGTVQPPGVRDRMNAVRAGLVPRSERTYR"
     misc_feature    complement(16578..16580)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(17160..17175)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 17.13"
                     /tool="antismash"
     gene            17257..17757
                     /locus_tag="KV381_RS20735"
                     /old_locus_tag="KV381_20735"
     CDS             17257..17757
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018489040.1"
                     /locus_tag="KV381_RS20735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_20735"
                     /product="SigE family RNA polymerase sigma factor"
                     /protein_id="WP_193464257.1"
                     /transl_table=11
                     /translation="MTVEEFEEFYARAVARLTGQLYVMTGDLQEAQDVVQEAFVKAWVR
                     RGRLERDGQPEAWIRTVAWRLAVSRWRFRRRSADAWGRGSGAPEHVEPPDPGHVVLVDA
                     LRELPAQQRRTLTLHYLCDLTVEQIAGETGLSTSTIKTHLVRGRAALAHRLHDPRIEEA
                     PDV"
     misc_feature    complement(17272..17285)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 13.98"
                     /tool="antismash"
     gene            17750..18223
                     /locus_tag="KV381_RS20740"
                     /old_locus_tag="KV381_20740"
     CDS             17750..18223
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018958798.1"
                     /locus_tag="KV381_RS20740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_20740"
                     /product="hypothetical protein"
                     /protein_id="WP_218785974.1"
                     /transl_table=11
                     /translation="MSEPRDPLRSLFREAGDFGQVRSVVDPASSITERGMRAQRRRMAV
                     VAVGVCLVVGGGGAVAVGLLPVRPEPVVPATSPSPSYPSPVPSEGLSTEQSSPPPSPST
                     TLPGGLPTGTGTGAPTGTSPTGTKPPPTSESTTSTTSTTSTTSTATDGATSTP"
     gene            18371..19594
                     /locus_tag="KV381_RS20745"
                     /old_locus_tag="KV381_20745"
     CDS             18371..19594
                     /GO_function="GO:0000009 - alpha-1,6-mannosyltransferase
                     activity [Evidence IEA]"
                     /GO_function="GO:0004376 - glycolipid mannosyltransferase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006506 - GPI anchor biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006126495.1"
                     /locus_tag="KV381_RS20745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_20745"
                     /product="mannosyltransferase family protein"
                     /protein_id="WP_218785975.1"
                     /transl_table=11
                     /translation="MTALSTLVRPEPRAEAPPPEPRAAGRIRRAAARLTPADRSVLWLY
                     LLTRISLWITAHLARWLFPSHPGTREAAPVLAPFQQWDANHYLHIARDGYFPAGTGPWT
                     SGWDNREAFFPGYPFLLRAVHTVVPDWTAAGLLISFIAGAVAVLALARIARAYLPEDVA
                     GRRTAVLFLLSPCAVFLAAGYTEALFLAFALPAWLAAMRHRWALAAVLTTAATTVRVSG
                     LFLAAAIGLLFVLSARTGRHWRTAGWTLLPALPPAAYSWYLHAHTGDWMAWKHAQERGW
                     YRTFHTPWEAWTNTWHGAFEGTQSTGYAAMFQAELAAMLVGLALVAILLRRRRWPEAVY
                     VALSLWALGTSYWYTSVPRATLLWWPLWIGLAAVSLRRPWFTTAYLCVAAPVTTIVALT
                     FLTGRWAG"
     gene            complement(19766..20041)
                     /locus_tag="KV381_RS36935"
     CDS             complement(19766..20041)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF045158.2"
                     /locus_tag="KV381_RS36935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF6879 family protein"
                     /protein_id="WP_306438361.1"
                     /transl_table=11
                     /translation="MNVLRPRSELGEEIRVLDAGTIPDLERDEHVPEVVILGSSVMYAV
                     IHDDDLKGAGARRFTDPDQVRTTTQEFEALSGVRSSRSSSRGRSCR"
     gene            complement(20072..20257)
                     /locus_tag="KV381_RS36940"
     CDS             complement(20072..20257)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="KV381_RS36940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_306438362.1"
                     /transl_table=11
                     /translation="MNASMFACFRSGAGEVLQRPDYLADFSRVHASDIHLLAKLERGQT
                     FKEPGTPSWEAFASGD"
     misc_feature    complement(20250..20261)
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 18.76"
                     /tool="antismash"
     gene            complement(20292..20561)
                     /locus_tag="KV381_RS20755"
                     /old_locus_tag="KV381_20755"
     CDS             complement(20292..20561)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003967338.1"
                     /locus_tag="KV381_RS20755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_20755"
                     /product="hypothetical protein"
                     /protein_id="WP_218785976.1"
                     /transl_table=11
                     /translation="MGRPWEADPETGFKRRLGKSALELGATSTGPECPDIWELENGDIA
                     VIGRDLTDSLGTRLPDGVSISRDERLVVIPRRMPIAAKADIPHE"
     misc_feature    20602..20617
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: medium, score: 21.64"
                     /tool="antismash"
     gene            complement(20762..21352)
                     /locus_tag="KV381_RS20760"
                     /old_locus_tag="KV381_20760"
     CDS             complement(20762..21352)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008404024.1"
                     /locus_tag="KV381_RS20760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_20760"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_086779532.1"
                     /transl_table=11
                     /translation="MSVQERKERERASRERLIVATARELAEQQGWDAVTTRRLAERIEY
                     SQPVLYSHFRGKREIIGAVALEGAAEMAGALRAATSATATATAEPRARVVALARAYLDF
                     AADNPAVYDAMFQLDGGLAFAQEDTPEPLKDAFAALLETLGEVAGDDVHPALFTELFWA
                     SLHGLATLTRAGRLPPEDSELRVELLVDRLAVV"
     misc_feature    complement(21335..21346)
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 19.28"
                     /tool="antismash"
     gene            21444..21890
                     /locus_tag="KV381_RS20765"
                     /old_locus_tag="KV381_20765"
     CDS             21444..21890
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006141888.1"
                     /locus_tag="KV381_RS20765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_20765"
                     /product="DUF1772 domain-containing protein"
                     /protein_id="WP_218785977.1"
                     /transl_table=11
                     /translation="MLNALEIVTTVIVGLLVGVEFSVAFVINRILYALPDDSTQLGRSH
                     GGRMLGAVMPFWYIGSMVLSAIWAIAGWGQEGIGLVVTAGGLLLVSVVMSILLLVPINN
                     LGKTWTPENRPADWKEQMNRWDRYHYIRVAVLIAAFTLLVAALV"
     gene            <21895..>22026
                     /locus_tag="KV381_RS37110"
                     /pseudo=""
     CDS             21895..>22026
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558177.1"
                     /locus_tag="KV381_RS37110"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MGGDKRDCPRTHGDREVLAAIVFVALSGCAWQQLPSVSFGPSVV"
     misc_feature    22335..22349
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.8"
                     /tool="antismash"
ORIGIN
        1 catctcgtcg cgggccagcg ggtcgaggtc cgacatcggc tcgtccagga gcagcaggtc
       61 gggccgcttg ccgaaggcca gcgcgaaggc cacgcgggtg cgctggccgc cggagagcgt
      121 gccgacccgc gcgtcgaagg ggacattgcc cgcgcggacg atccgctccg ccgccaccgc
      181 gtcccagccg gggttcagct cggcgcccat ccgcagggtc tcggccacgg tgaaccgctt
      241 gaacagcggc ttctcctgcc cgaggaacgc gaaggtgggc atcacggcgg ggtcgtcgac
      301 cggtacgccg aagatccgca gctcgccggt ggtcggctgc acctgccggg tcgccagccc
      361 gagcagggtg ctcttgccgg ctccgttcgg gccgaccaga ccgcagatgc ggccggccgg
      421 gatccggaag gagcagtcgc gcagcgccca gccgcgccgg tagcgcttgc ccaggccgcg
      481 ggcctccagc gcccagctgc cggacgtcgc gttcggggtg ctcgtgtgtg ccacgcgcct
      541 cacctcggtt ccgtgaatcc gtgatcgtga ttccatgaat caattaatgg aatcatggag
      601 tcgtgaggga atgactgtca agtgaggcag gccggggagg gagggggcgg gaagagggga
      661 ggtgggtttg ccggggtggc gccccggtcg cggccgaacc cggcggcagt ggccccgtac
      721 ccgttaggct cgccccatgg gcagccaccc ggaaagtctt ccgaacccga ccaccccggc
      781 cggccgcgag gggctcgacg ccgtgctcgc ccggcccgac cgcgcggtcg tcgccctcga
      841 cttcgacggc acgctcgccg acatcgtccc ggaccccgaa caggcccgcg cccaccccgg
      901 caccgtggcc gcgctcgccg cgctcgcgcc gaaggtcgcc gccgtcgccg tgatcaccgg
      961 ccgcccggcg ggcgtcgccg tgcgctacgg aggcttcgcg ggcgtgcccg gcctggaaca
     1021 cctcgtcgtg ctcgggcatt acggggccga gcgctgggac gccgtcaccg gcaccgtcca
     1081 cgcgcccgcc ccgcatccgg gcgtcaccgc cgtgcgcgcc gaactccccg gcgtactgca
     1141 cgagttcggt gcgtggaatg gcacctggat cgaggagaag ggccaggccg tcgccgtgca
     1201 cacccggcgc gccgaggacc cgcaggcggc cttcgagtcg ctgcgcggac ccctcggcga
     1261 gctggccgcg cggcacgggc tgatcgtcga accgggccgc ctggtcctgg agttgcgccc
     1321 gcccggcatg gacaagggcg tcgcgctcgc cgggttcgtc gccgagctgg acgcggagtc
     1381 cgtgatctac gcgggcgacg acctcgggga cctcgccgcg ttcgccgcgg tggagaagct
     1441 gcgcagcgag ggcccggacg gcatccccgg tctcctggtg tgcagcggca gcaccgaggt
     1501 gcccgaactg gccgagcgcg ccgacctgtc ggtgccggga ccggccgccg tcgtcgcgtt
     1561 cctggcggcc ctggccgagc ggatctgagc cgggccagga cctcggctca cccctcccgc
     1621 agcgcctcca gctggtccag gaaccactgc tgcggcggga gcgcggtcgc cgcctccgcg
     1681 agccgcttcg tgcggcccga ccgctcgtcc ccgctcatcg tcagcgcctc gtgcagggcc
     1741 tccgccgtgc ccgtcacgtc gtacgggttc accacgatcg cgtcctcgcc cagctcctcg
     1801 tacgcccccg cctcccgcga cagcaccagc gcgcagccgt ggtcggagac gacggggacc
     1861 tccttggcga ccaggttcat gccgtcgcgg atcgggttga ccagcgccac gtccgccagg
     1921 cggtacgcgg ccagcgagcg ggcgaagtcg tccttgacgt ggaggaccac cggggtccag
     1981 ctctccgtgc cgtacgccgc gttgatctcc gtggccaggg tctgcaccgc cgccgtgtag
     2041 tcccggtaga cggcgaggtc ctgccgggag gggtaggcga aggcgatgtg gacgacgcgc
     2101 tcgcgccact cggggcgggt gtccagcagc gtgcggtagg cgtgcaggcc gcgcacgatg
     2161 ttcttggaca gctcggtgcg gtccacccgg acgatcgtct tcctgccctc gcccacctgc
     2221 tcgcgcagcg ccgccatccg ctcgtccacg tccgcctcgt gcgagcgccg gcgcaggaag
     2281 tccgcgtcgg ccccgaggcc gtgcaccccg accctggtcc ggcccgtgcc gccgaggatc
     2341 tccgtacagc agccgatgaa cgcgtccgcc cagcgacggg tcaggaacgc ggcccggtcc
     2401 gcgccgagga tgccgcgcag cagctgctcg gcgatgtcgt cgggcagcag ccggaagtag
     2461 tccaccgggg cccacggggt gtgcgagaag tggccgatcc gcaggtccgg gcgcagttcg
     2521 cggagcatgc cggggaccag ggccaggtgg tagtcctgga ccaggaccgc cgcccccggc
     2581 cccgcctcct ccgccagcgc ctccgcgaag gcccggttgt acgtctcgta cgccgcccac
     2641 tgccgccgga actccgtgtc gaagaccggc tcgacggggg tctggtacag caggtggtgg
     2701 acgaaccaca gcaccgagtt cgcgatgccg ttgtacgcgt cggcgtgcac ctcggcgtcg
     2761 atgtcgagca tccgcacgcc ctcctcgccg accccgcggc gcaccgcctc gcggtccccg
     2821 tcgccgaggg ccgcgcagac ccacagcttg tcgtcgacgg cgctcagccc ggagacgaga
     2881 ccgccgccgc cgcgcttgga gtccagcgtc ccgtcctcgc cgagcgtgta cgtgaccggg
     2941 ccgcggttgg acgcgacgag gacctgggcg ttcgaggaag acgtgtgctc ggagaccatg
     3001 tagcggaacc tagcccgttc gggaagccgc caaacgcctc ggaggggcac gcgccccgcc
     3061 cgctcacgcc gcgtggcgct ccgcgtactc cgcgatctcc cgcatcggcg gccgctcctc
     3121 cgtgtccacc gcatgggtgc gcggcacgaa gccgtcctcg ccgcgttcga actgggtcag
     3181 cgcgggccgc accagatggc cacgggagag ccgcagctgc gccgtgcggt agatcgccgc
     3241 cgccatccgg cccagcgcct gcccgtcctg gtggcggtgg atgcgtacgc cgacgtcgac
     3301 ctggcccagc gcgtccaggc ccaccgtgtg cagggcgtcc accagcaggc ccagctccac
     3361 tccgtaaccg accgggaacg gcagccgctc cagcagggac cgccgcaccg cgtactcgcc
     3421 gcccagcggc tgtacgaatc cggccagctg cggccagtgc agattgagca gcggccgtgc
     3481 caccagttcg gtgacccggc cgccctgacc tgccctgtcg ccgagcggac ggtcgtacat
     3541 cgccttgacg aactggaccg tggggtcggt gagcagcggg ccgatcgtgc ccgagacgaa
     3601 gtccgccgag aagtccttga ggtcggcgtc cacgaagcag acgatctcgc cgctggtcac
     3661 caggagcgac cgccacagca cctcgccctt gccgggcagg gccgggatcc ggggcaggat
     3721 cgcgtcccgg tggaccaccc gcgcgcccgc cgcccgggcc acggcggcgg tggcgtcggt
     3781 ggagccggag tcgatcacca cgagctcgtc gaccagccgg accttctcca tcagctcccg
     3841 gcggatcgtc gccacgatcg cgccgaccgt ggcctcctcg ttcagcgcgg gcaggaccac
     3901 gctcaccgac gtacggcgcg gatcggcgtc ccgggcgtcg gtgagccggt tcagcgggcg
     3961 gtcgccggac gaccaggaac gcctggtcag ccagcgttcc acctcttcga gcacggtcgg
     4021 cactccctgt gtgtgatcca tctcgcggtt cggacgacta tctcaacggt ccgatgcttc
     4081 ggttacagtc ttgaacaacg cgtatggccg tcgcatgtcg gggtcggacc gcacataaac
     4141 gcctggatcg aagatccagc gccatagagc tcatccagag ggactgaggg aacggcccgt
     4201 tgaagtcccg gcaaccctcc tgccgaccgc gaggtcacgg tggggaaggt gccaattccg
     4261 tcttgtggcg aaatgcgtcg caaggaagat gaggagaaag ggcctccgcc atcatggctg
     4321 ttcagaccgt tgcaggtaat gccaccaccg cccccgtgga cctcggtccc gccgcggcgc
     4381 tttcctgccg cgagtgcggc gagcgtttcg agctcggccc ccttttcgcc tgtgcgtcct
     4441 gtttcggacc gctggaagtg gcctacgacc tgcccaccgg ctccccggag gagctgcgga
     4501 agcgcatcga ggccggtccg gacaacatct ggcgctacgc accgctgctg ccggtgccct
     4561 ccgatgtcgc ggagaagccc aacatcaacc ccggcttcac caagctggtc aaggccgaca
     4621 acctcgcccg tgagctgggc gtcaccggtg gcctgtacgt caaggacgac tccggcaacc
     4681 cgacgcactc cttcaaggac cgcgtcgtcg cgatcgccgt cgaggccgcc cgcgccttcg
     4741 gtttcaccac cctctcctgc tcctccacgg gcaacctggc cggagccgtc ggcgccgccg
     4801 ccgcccgcgc cggactgcgc tcctgcgtgt tcatcccgca cgacctggag cagggcaagg
     4861 tcgtcatggc cgcggtgtac ggcggtgaac tggtcggcat cgagggcaac tacgacgacg
     4921 tcaaccgctt ctgctcggag ctcatcggcg acccgctcgg cgagggctgg ggcttcgtca
     4981 acgtcaacct ccgcccgtac tacggcgagg gctccaagac gctggcgtac gagatctgcg
     5041 agcagctcgg ctggcggctg cccgaccaga tcgtcatccc gatcgcgtcc ggttcccagc
     5101 tcacgaagat cgacaagggg ctccaggagc tgatcaagct cggactcgtc gaggaccggc
     5161 cgtacaagat cttcggcgcc caggccgagg gctgctcccc ggtctccgcc gccttcaagg
     5221 ccggtcacga cgtcgtacgg ccccagaagc cgaacaccat cgccaagtcg ctggccatcg
     5281 gcaacccggc cgacggcccg tacgtcctgg acatcgcccg ccgcaccggc ggtgcggtgg
     5341 aggacgtcac cgacgagcag gtcgtcgatg cgatcaagct gctggcccgc accgagggca
     5401 tcttcggcga gacggcgggc ggggtgacgc tcggcgtgac gaagaagctc atcgaggccg
     5461 gcgtcatcga cccgacgctc accaccgtcg tcgtcaacac cggcgacggc ctgaagacgc
     5521 tcgacgcggt ctccgccacc tcgcaggcca cggccaccat caagccgagc ctggacgcct
     5581 tccgcgccgc gggcctcggc accgcctgac gaccaccccg taccgaagga agaagggcac
     5641 caccatgagc gtcaaggtcc gcatccccac catcctccgt acgtacacgg gcggccaggc
     5701 cgaggtcccg gcggagggcg cgaagctctc cgaggtcatc gagtccctgg agaaggacca
     5761 cccgggcatc gccgcccgcg tcctggacga ccagggcaag ctgcgccgct tcgtgaacgt
     5821 gtacgtcaac gacgacgacg tgcgcttcga gggcggcctg gacgcggcca cgccggacgg
     5881 cgccggcgtc tcgatcatcc ccgcggtcgc cggcggttgc tgaaccgccc cgggccgctc
     5941 cacggcggcc cccaccgcac ctctgagtga ccacgattgc cccctccgcg agagaagcgg
     6001 agggggcaat tctgcatggt tgagcacggt acagttgggg aagccccatc cgctgcccgt
     6061 gccgcccgca tatgagaatg cgcccggccc cgataagaag cagccaaagt gcgtgaacct
     6121 cttgcggcat aagtgccctt tgcctggccc gacttgcccg taaatctcag caaacccgca
     6181 tattcgcgtg ttcttccgcg cccagatttc tcgtccgatt gacctgttgc agagggcagt
     6241 tgggcggata cattcggccg cggtcgacgc gctgcggcgc cgcacaccct ctcctgtcgg
     6301 agggtgagtt ccgacccggg tccgcgaagt gcggtcccgt gcaagggcca gtaatagggg
     6361 agttaggcat ggctcagggc accgtcaagt ggttcaacgc ggagaagggg tacggcttca
     6421 tcgcggtcga cggtggtgcg gatgttttcg tccactacag cgcgatccag atggacgggt
     6481 accgcaccct cgaagagggt cagcgagttg aattcgagat ctcgcagggc cagaaggggc
     6541 cccaggccga catggtcaag ctcgccgtcg gctgagctcg gcgcggtcgt ccgacgacac
     6601 cactcacgcc cgtagggccc gaaccccgga tcagggggat cgggccctac gcgcgtccgg
     6661 tggcccggtc cggcgatccg gtccggtgac cggtcgcggg ggcgcgccga cgtccgcatc
     6721 cgacgccgcc gctgtccaca tccgacgagg gacgcttgca ctcgcagggg tcgagtgcta
     6781 atcattggcg ttagcactct ccaggtgaga gtgacagaac ttggaccggg ccggtgaggc
     6841 ccgcaggcgc ggtggggcaa ggaaccacca cgcacgctgg ccgtccgtcg cgggcgcctc
     6901 tcggtccgga gaaatccacc cctgtccggg aggaccactt cacatggcca agatcatcgc
     6961 gttcgacgag gaggcacggc gcggtctcga gcgcgggatg aaccagctcg ccgacgccgt
     7021 caaggtcacc ctcggcccca agggccgtaa cgtcgtcctc gagaagaagt ggggcgcgcc
     7081 cacgatcacc aacgatggtg tttccatcgc caaggagatc gagctcgagg acccgtacga
     7141 gaagatcggt gcggagctgg tcaaggaggt cgccaagaag acggacgacg tcgccggcga
     7201 cggtacgacc accgccaccg ttctggctca ggctctcgtc cgcgagggtc tgcgcaacgt
     7261 cgccgcaggc gccaacccga tggccctcaa gcgcggcatc gagaaggccg tcgaggccgt
     7321 ctccgccgct ctgctggagc aggccaagga cgtggagacc aaggagcaga tcgcttcgac
     7381 cgcctccatc tccgccgccg acaccgagat cggcgccaag atcgccgagg cgatggacaa
     7441 ggtcggcaag gaaggcgtca tcaccgtcga ggagtcccag accttcggtc tggagctgga
     7501 gctcaccgag ggtatgcgct tcgacaaggg ctacatctcg gcgtacttcg ccaccgacat
     7561 ggagcgtatg gaggcgtcgc tcgacgaccc gtacatcctg atcgtcaact cgaagatcgg
     7621 cagcgtcaag gacctgatcc cgctgctgga gaaggtcatg cagtcgggca agccgctgct
     7681 gatcatcgcc gaggacgtcg agggcgaggc gctctccacc ctggtcgtca acaagatcaa
     7741 gggcacgttc aagtccgtcg ccgtcaaggc cccgggcttc ggcgaccgcc gcaaggccat
     7801 gctcgcggac atcgccatcc tcaccggtgg caccgtgatc tccgaggagg tcggtctcaa
     7861 gctggagaac gccggcctgg acctgctcgg ccgcgcccgc aaggtcgtca tcaccaagga
     7921 cgagacgacg atcgtcgacg gcgccggtga cagtgaccag gttcagggtc gcgtcaacca
     7981 gatccgtgcc gagatcgaga actccgactc ggactacgac cgcgagaagc tccaggagcg
     8041 cctcgcgaag ctggccggcg gcgtggccgt catcaaggcc ggcgccgcca ccgaggtgga
     8101 gctcaaggag cgcaagcacc gcatcgagga cgcggtgcgc aacgccaagg ccgccgtcga
     8161 ggagggcatc gtcgccggtg gtggcgtggc tctgctccag gcctcggccg tcttcgagaa
     8221 gctcgacctc acgggcgacg aggcgaccgg cgccaacgcc gtgaagctcg cgctggaggc
     8281 cccgctcaag cagatcgccg tcaacggtgg tctcgagggt ggcgtcgtcg tggagaaggt
     8341 ccgcaacctg ccgatcggtc acggcctcaa cgccgcgacc ggcgagtacg tcgacatgat
     8401 cgccgagggc attctcgacc cggcgaaggt cacgcgctcc gccctgcaga acgccgcgtc
     8461 catcgccgcg ctcttcctca ccaccgaggc cgtcatcgcc gacaagcccg agaaggccgg
     8521 cgcggccgct ccgggcggca tgccgggcgg tgacatggac ttctgatcag ccacggaggc
     8581 tccggcctcc ccgcctgatc cgaagttccg cgtacgtccc cgtacgtgcg cagtacgtcc
     8641 gcagtacgtc ccacaggggc ggtatctcct tcacggaggt gccgcccctg tggcgttccc
     8701 ggccgcactg gaacaatgcg gccggggggc cggtggaccg gtcgtcgcga caacggggga
     8761 cgggacgggg acggggacgg ggacgggacg ggatggccaa ggattggaag ggggcctcgt
     8821 tagtgctggg cggggccgcg ctgttcgtgc tggggctgtt cgtcgtggtg accggggcgg
     8881 ggctctccgg cgccctcggc atgcgggtcg agaccttcgg ccggatcgac tgcgacgaca
     8941 cgcggacgaa gaaggggcag accgtctggc actgcttcgg cgagagcccg gtccagcagc
     9001 gcgccaacga ggcggagcgc gaacgggtgg cccgggaggc gctgcgcgcc catgtggacg
     9061 gcgtgccgcg gccggcggag accgggcgca ccaggatcct cttcgccgac cacgacggcc
     9121 gtacggaccc cgagaccatc accgcgaccc aggtgttcga cggcggacgg tggtacgccc
     9181 actcctcgat ggtcgtcggc tacggcatga tcccgctgct gctgggcgcg ggagcggcgg
     9241 cctggggcgg ctaccggctg cgcggacggt aggtcgggtc cggcgggtcc ggcgggtcca
     9301 acgggcacac tccgggcctg tggccgaatg cgtacttgtc gtgcccggtg ccgtgctgca
     9361 ccgcgcgttc ctccgttttc ggcgatgtcg gtggcgcgcc ggcgacccgt gaggtacggc
     9421 cggtgcgcgg gctgccgggc cctcgcccgc catggttccc gcgttccgcc gcacgccgcc
     9481 ggctctcttg gcagctcact gcccggtccg gccgacgcgt acagccattg gtccagtcca
     9541 ctacctcgcc gcgctccggt gctgtgcgac tgcacatgcc gaccggtcgg tgccccgcgg
     9601 tgccccgcgg tgccgtggag aggccgggag cggccctgcg tgccggcccc ggtcctcgcg
     9661 ctatccagcc aacttcgcac ggtaagtcgg aatcatgcgt accggatcgg cagcgggaca
     9721 tgatggctct ggtgttcacg tggtgaacac cagccgcacg aataacttca gttatgcagc
     9781 tgccagttgg gcataacggt cgtcaaccgc acagaaggga aggtgtcatg aagcagcaga
     9841 agaaggctta cgtgaagccg tcgctgttca agcagggcga cttttcgaag aagaccgccg
     9901 gttacttcta cggctcgtac aaggagtact gggtccgccg catcatctga tccggccccc
     9961 ggtttcccgc gcgtcgtacg agaacttccg gaaggtgaac atgcccggcc aactgcgtga
    10021 ctacttcgtc gtcctgccgg acagcgtggc gggagcggcg gtggccgggc gacttcctcc
    10081 gggggcgggc ggggggacgg tggtcgccca cgcatccggg cggccctggg tcctcgcccg
    10141 cccgctggtc cgccgggtga gccacctccg ccggggcgac gacgccctcg tgctcatcgg
    10201 cccggaccgg gtctccgacg ccgtgctctc cggtctcctg gaaggcgccc gcgaccgggc
    10261 gggcctggaa cgccgcctcg cccgtctgcc cggcctccac catgtgatcg cccggctctc
    10321 cgggcagacc tggatccggg gcaccgcctc cgggctgcgc cggatctacc acgcccggca
    10381 cccggaggcc ggaaccatcg cctccgaccg ccccgccgtc ctcgcccgcc tgatcggcgc
    10441 acccctggac gacggcgcac tggccctgcg catgctcgac ttcctgccgc accccctgag
    10501 ccgccgcgtc gtgtggcgcg gcgtgcacga gaccggcgcc gggtacggcc tggccctgcc
    10561 cgccgcagca ccgggcacgg ccgccgtccc cggccccacg gagcaccgct ggtgggagcc
    10621 gccacccgcc gaactcccgc tggccgacgg ggcgcaggcg ctcggcgacg ccatcgccgc
    10681 ctccgtacgg gcccatgtcg gcggcctgga ccggatcagc tgcgagctgt ccggcggcat
    10741 ggactccacg gccctcacct tcgccgcccg cgcgaccggc cccgccgaac tcgccctgct
    10801 caccgtcgcc gcgcgcgacc gctacagcga ggacgagacg tgggcgcgca gagcggtgga
    10861 ggcggcacga gaaggaggtg ttggggcgcg agggggcgag gcggcgcgag gcggcgaggc
    10921 gacgcggagt ggcggggcgg cgcgaggtgc tggcgggaac cgagacagta acgcggcgcg
    10981 tacgcgcgat gcggggcgga agggtggcga cgtcaccggc ctggagcacc acatcatccc
    11041 cgccgacgac gccccctact tctacgccga gctcgccgcc accgcagccg agttgaacga
    11101 cgagccgctc cccgtggccc ccggccgggc ccgcgcgcac ctgctcctga gccgcgccca
    11161 cgccaccggc tcgcgctacc acctcaccgg ctacggcgga gacgaactct tcctcggcct
    11221 gccccacgcc taccaggacc tcttccacgg caacccgctc actgcctgga accacctcag
    11281 cggcctgcgc caccagctcg gctggccgtt cctgccgacg ctgaaggccc tgctgaaccg
    11341 ctccacgttc ccccgctggc tcgccggcgc gatcaccgcc gaaccccagc cggtcacccg
    11401 tacgccgctg ctctcctggg gcgtacggca gtcgctgcgc ccctggttca cggagcacgc
    11461 caacgccctg atcgccgagg agttccgggc cgccgccgag cgcgccgagc cgatcgaccc
    11521 gtggcgcggc cggcacgtcg acatcgacgc cgtacggatg ggggcccggc acttccaggc
    11581 gatggaggac atcggcatga cgatcgggct gccggtcgcc gcgcccttct acgacgaccg
    11641 ggtcctggag gcgaccctcg ccgtacgcct ggcggagcgc atcagcccgt ggcgctacaa
    11701 accgctgctc gtcgaggcga tgcgcggggt ggtcccggac gcgctgctgg cccgcacgac
    11761 gaaggaccac atgtcctccg acgaacacca ggggctgcgt caacacgcgt cggaactggc
    11821 cgacttgtgg accggctccc ggctcgccga gcacggcctg gtcgactccc gccacctgct
    11881 ccggctcgcc gccgaaccct tctctccggt cctggtcgag cactccgtca gctccaccgt
    11941 ggccggcgag acctggctcc gcaccgccga gaacgcctgg ccgacgccga cgccgacgcc
    12001 gacgccgacg ccgacgccga cgccgacacc ggcacagtcg ccgtcactgc caccccaccg
    12061 cacctccacg accagcgagg caaccctgtg aagctcagaa aaggcatcgc cgtcacgacc
    12121 accgagtacg gcggcgtcct cctcgacgaa aaggacggca gctactggca gttgaacgac
    12181 accagcatca tcgtcgtcga caccctcgcc gccggacaca cccccgacat cgccgtggag
    12241 cggatcctcg ccgcgttcga cgtcgagcgc gccgaggcgg agtcggatgt cgcggaactg
    12301 acccggcagc tcgtcgacgc gaagatcctg cgcccatgac caccgagatg acgatgccgc
    12361 gccggggcgc gggagcgggc ggggtgcggc tgcgcacggc catcgtcgcc gcgttcgtcc
    12421 tggcccgcct gaagcccgga cggctgcgcc gggtattggc cagatgcgcc cgggacgcgc
    12481 gcccggcctc gtacgcggag acgatggagg tgctggaggc ggtcgtcgcc accagccgcc
    12541 gctgcgcgag ccgttacggc tgcctgcccc gctcggtggc cgtcgccctg gcctgccgga
    12601 tgtccggcgt ctggcccgac tggtgcgccg gggtgcggtc cgccccaccg ttcgccccgc
    12661 atgcttggct gcaggcggag ggccgtacgg tcggggaaca ggcggaaccg gcggatctgc
    12721 gtcccttgat ggtggtgacg gcggcggcgg tcacggcagg cggaggggta cgggatgagc
    12781 gcggtgtcgg ggacggcggg ggcggaagcg agagccgggg cggaggcggc cggcagcggg
    12841 cctgaggacg cggggacacc ggcggcgggg cccgccggtg agccggtggg gcccgggcag
    12901 accgccggtg tgccggtggg gcccgggcag cccaccgagg aggcggcaga gcccgagcag
    12961 cccaccgagg aggcggcaga gcccgagcgg cccactgggg aggcggcaga gcccgagcgg
    13021 cccactgggg aggcggcaga gcccgagcgg cccactgggg aggcggcagg gcccgagcgg
    13081 cccaccgggg aggcggtagg gcccgagcgg cccaccgggg aggcggcggc ccccgaggcg
    13141 ccggccggtg ggtcccccgc ggataccacc gggaaccccg cccagggcaa gtccggcccg
    13201 tcccccctcc gcctcctcct tgcccgcgtc cgcccgcacc ggggcgtact gatccgcgcg
    13261 ggcctgctct cgctcaccgg ctccgcggcc ggcctggcga tgcccctgat ggcgaagtac
    13321 gccgtcgacg cgttcgccgc cgaccgctcg cccgtggccc cgctcgtcgc gctgaccgcg
    13381 ctcgtactcg ccggagcctg catctccgcg tacgggcgct acctcatggc ccgtacggga
    13441 gagggcgtgg tgctccgtgc ccgagaccaa ctcgtgggcc gcatcatgcg gttgaaggta
    13501 ccggcggtgg accgcctcac ccccggcgac ctgcagtccc gggtgaccag cgacaccact
    13561 ctcctccgga cggtcctctc cagcggtctg gtcgagtcgt tcaacagtgt gctgatgctg
    13621 ctgggaacgg tcgcgttcat ggcgtacatg gacgtgacgc tgctgggcgt gacgctggtc
    13681 gtcatcgtcg gcatcggagc cgtaacggcc ttgctcatgc cgcgtattca gcgtgcgcag
    13741 ctccgggcgc aggagtccgt cggggcgatg ggcgcggccc tggaccgggt gctccaggcg
    13801 ttccgtacgg tcaaggcgag cggtgccgag gagcgggaga cggcagccgt ggcggaggcg
    13861 gcccggcacg cgcacgaccg gggcgtctcg gtggcgaaat ggtcctcggt ctcggacgtc
    13921 acgatgatga tgtcgatcca actcgccttc ctggccgtgc tgggcgtcgg cggagcgcgg
    13981 gtcgcgtcgg gctcgctgga gatctcctcg ctgatcgcgt tcctgctcta cctcttctac
    14041 ctgatgggcc cgatcggcgg tctggtcgag ggctggacgg ggctgcagag cggcctcgcg
    14101 gcggtgcgcc ggatcgacga ggtggagtcg ctgccgggcg agacctccac cggatccggg
    14161 gccatggagc cggagggcgg accgctcggg gtcgccttcc aggacgtgac cttcgggtac
    14221 ggggacgagc gcgcccccgc ccacaagggg gtgacgttcg acgttccggc cggtggactc
    14281 gtcgcgctgg tgggcccgtc cggggcgggc aagtcgacgg tgttcagcct gctggaacgc
    14341 ttctacgacc acgacggcgg cacgatcacc gtgggcggcc gggacatccg cgactggccg
    14401 ctggccgaac tgcgcgcctc gctcgcgtac gtggaacagg acgccccggt cctggccggg
    14461 acgctccgcg agaacctcct ctttgccgcc ccggaggcgg aggagaagga gctgacggcg
    14521 gcggtggccc gtacccgcct ggacgccctg gtcgaccggc tgccggacgg cctggacacg
    14581 gcggtcggcc accggggcgt cacgctctcc ggcggcgaac gccagcggat cgccatcgcc
    14641 cgcgccctgc tgcgccgccc ccggctgctg ctcctcgacg aggtgacctc gcaactggac
    14701 gcggtcaacg agcaggcgct gcgcgacgtc atcctcgaaa tggccgagca ggcaacggtg
    14761 ttggtcatcg cacaccgtct gtccacggtc cgccacgccg accgcatcgt ggttctggag
    14821 gagggccggg tccgcacggc gggcacgcac gaggagctga tcgccgggga cgacctgtac
    14881 cgcgagctgg cgacgacgca gctggcggcg gaggtggcgt gatggcgggg cggaggcggc
    14941 gcgatgacgg ttcggcggcg aatgccatga tgggggacaa gggaaccgga accggcacca
    15001 tcgaaagccc cgaaacccca gcgacgcctg cgacacccgc gacgcctgcg acacccgcaa
    15061 cacccgcaac acccgcgacg cccgcaacgc tttacgggcc cgtctcgctc ggcttcggcg
    15121 tcatcgcgct gatcgccgcg ttcttcctcg gcctgttcgc cctcctggcc gggagtctgg
    15181 cgatcacctt cggtgtgctg ggcctgatcg gcgggtacaa ccggccccag tgcctcgcgg
    15241 gcctcgtcct gggagccgtg ggcgtgctcc acccgctctc gttcctcttc gccttcacgg
    15301 gcggcttctg accgcgtcag aaccgagggc ggcgggtcag cgggcgtagt ccttgagctc
    15361 ctcggtgtcc agggtgatgt cgacggggtg ggggagggcg gcggccttgc cgtactcgta
    15421 cgtcgtccgc tgccggtacc ggccgttctc cggctcgctg tacacgacga gggcatcgtg
    15481 gtcgcggtcg atcaggaggt agaccgggat gcctgccgcg gcgtacccgt cacgcttctc
    15541 cgtgcgatca cgatggtccg tgtcgtggtc gtgcgacgtg acttcgacgg tcatgaggac
    15601 gcggtccggg ttcgaccact cgccgtcacc cgcgaagcgc cccgcgcggg ccagggtgcc
    15661 gtccgggcgg gcgcggccgt tgcggtatcc gccgatccgc agtccgcgtt cgcggtacag
    15721 ccgcagttcc ggctgctgct gcatgcactg catcgcgacc cacatgatga tctcgtcgtg
    15781 gtccccgtcc ggcacgggct tgacctccag ctttccgttg atgagctcaa gcgtcacggt
    15841 ctcgggggcc gtccgggcaa gctgctcgaa ctcctcgacg gacatctggg cgtgcggtgc
    15901 gtgatcggcg gagctggggg tcatggcgtc gcctcctccc ctccatcgtg ccccgtcgga
    15961 tctccgggcg agccgcacgg tcatcggtat gtcctttcgg atcgaggaac gagcccggcc
    16021 cggaccgcgt tcatccggtc ccgtacgccg ggcggctgca cggttcccgg cggccccacc
    16081 ggcggctcgg gggacggccc ccggcacggc cggcagaggc cgccgaggag cgcttcgggc
    16141 gagccgggca ctccgcactt gccgcattcg agggtgcgca ggacggtccg gggtcccggc
    16201 aggaccggct cgggcggcag cttgtcgcgc agccgccgtt cgacgaggcg ggcggcgcag
    16261 tggacggggg acggcagccc gctggtgagg gcgtgcagca gctccgcctc ggtcgcgccc
    16321 cgcgcgatcc actcaccgac ctgcggctcc aggcgtacgc agtcggcggc ggacagcgtc
    16381 agggcggggg cggtccgccc cagggccgcc agcaggatga acgcccgcga gcgggtgggc
    16441 cgttgcggtt cgtccggcgg agcgtcgccc cgggtgtagg cgttccacca ggcgtcctcg
    16501 cgtgcggtgc gggagaagaa ggtccgggtc acccagagca tgacctcgtc ggtgatcacg
    16561 cactcgctgc cgcgccgtaa gtgcccggcg tcctggagcc ggttgagggt ggtgcgcagg
    16621 gcgcactggc cgtacgggag gtgcttggcc agcgtcttca cggagatgtc ggagccgtcg
    16681 ggcagccggt cgatgtaggc ggcgacggag gcgtcacggg ggaggaggtg ggcgaagtcg
    16741 cggtcggtgc gcggacgttc gccgggcgcg gagcgcttgc cgtagccggg gttggccatg
    16801 gggtgcgggg gtgtgggcgg ggtctcgcgc ggagcgcggg gtgcatcact aaactggctg
    16861 tcagccatgg ggatcgcttt cttcgctttc tcgatcttcg gtggctagac ccctgtcggt
    16921 gttggagcac cggtgggggt cgtcttttgc ctggtcgtgg tcttcccgca cgctagagcc
    16981 tggcgaccgt gcgtcgcaac tcgatcacaa actgtcaact tcgcagccag ggtgggcggg
    17041 tgggactact gacccatcca ccccatcact gttaagagcg ctcggatctc gccgcttgag
    17101 cttcgggaga tgcgtggtga gcggcggggg tgaggggagg gcctgggccg ttcgggtcct
    17161 gtgacgaccg tcacctcgga aatatggccg gtggtgtcga ccggatggcg cgcgccgggc
    17221 gtatacccgg tgaagcgaaa gatccgggag caacttttga ccgtcgagga gttcgaagag
    17281 ttctacgccc gggcggtcgc gcgtctcacg ggccagctgt acgtgatgac cggcgacctc
    17341 caggaggcgc aggacgtcgt gcaggaggcc ttcgtcaagg cgtgggtccg gcgcggccgg
    17401 ctggagcggg acgggcagcc ggaggcgtgg atccgtacgg tcgcctggcg gctggcggtg
    17461 agccgttggc gcttccggcg gcgttcggcg gacgcctggg gccgggggag cggtgcgccc
    17521 gagcacgtgg agccgccgga cccgggccat gtggtgctgg tcgacgcgct ccgggaactg
    17581 cccgcccagc agcggcggac gctgaccctg cactacctgt gcgacctcac ggtcgagcag
    17641 atcgccgggg agaccgggct ttccaccagc acgatcaaga cgcatctggt ccgtggacgg
    17701 gccgcgctcg cgcaccgtct gcacgacccc cgcatcgagg aggctcctga tgtctgaacc
    17761 acgggatcca ttgcggtctc tgttccggga ggccggtgac ttcgggcagg tccgctcggt
    17821 ggtggacccg gcgtcgagca tcaccgaacg cggcatgcgc gcgcagcgcc gccggatggc
    17881 cgtggtcgcg gtgggcgtct gcctggtcgt cggcgggggc ggggcggtcg cggtgggcct
    17941 gctgccggta cggccggaac cggtcgtccc ggcgacgagt ccgtcaccga gctacccctc
    18001 gcccgtaccg tcggagggcc tgtcgaccga gcagtcgtcg ccgccgccct cgccgagcac
    18061 cacgctgccg ggcggtctgc ccacgggtac gggcacgggt gcgcccacgg gcacgagtcc
    18121 gaccgggacg aagccgccgc cgacatccga gtcgacgacg tcgacgacgt cgacgacgtc
    18181 gacgacgtcg acggcgaccg acggagccac gtcgacgccc tgaccccgta gccgtagccg
    18241 tagtccatag cccgtacccc accccacccc agcccccacc ccaccccttc cgtgccccgg
    18301 cggcttcacc gggcgatccc gcacgccttc acctcggcac gtccgtgagg catgcccgaa
    18361 aggtgcccgc atgaccgccc tgtccacact cgtacgtcct gagccccggg ccgaggcccc
    18421 gccgcccgag ccccgggcgg cgggccggat ccgccgtgcg gccgcgcgcc tgacgcccgc
    18481 cgaccgcagc gtcctgtggc tgtacctcct gacccgcata tccctgtgga tcacggccca
    18541 cctcgcccgc tggctgttcc cgtcccaccc cggaacacgg gaggcggcac ccgtcctcgc
    18601 gcccttccag cagtgggacg cgaaccacta cctccacata gcgcgcgacg gctacttccc
    18661 ggccggaacg ggcccgtgga cgagcggctg ggacaaccgg gaggcgttct tcccgggcta
    18721 ccccttcctc ctgcgcgccg tgcacacggt cgtcccggac tggacggcgg ccgggctgct
    18781 gatctcgttc atcgcgggtg cggtggcggt gctggccctg gcccgtatcg cgcgggcgta
    18841 tctgccggag gacgtggcgg gccgccgtac ggctgtcctc ttcctgctct cgccgtgcgc
    18901 ggtgttcctg gccgccggtt acacggaggc gctgttcctc gcgttcgccc tgcccgcgtg
    18961 gcttgcggcg atgcggcacc ggtgggcgct cgccgccgta ctgacgacgg cggcgacgac
    19021 ggtgcgcgtc agcggcctgt tcctcgccgc cgcgatcggg ctgctgttcg tgctgtccgc
    19081 ccggacgggt aggcactggc ggacggcggg ctggacgctg cttccggcgc tgcccccggc
    19141 cgcgtacagc tggtatctgc acgcgcacac cggcgactgg atggcgtgga agcacgcgca
    19201 ggagcggggc tggtaccgca cgttccacac cccgtgggag gcgtggacga acacgtggca
    19261 cggggcgttc gagggtacgc agtcgacggg ctacgcggcc atgttccagg ccgagttggc
    19321 ggcgatgctg gtgggcctgg cgctggtggc gatcctgctg cgccgccgtc gctggcccga
    19381 ggcggtgtac gtggcgctca gcctgtgggc gctgggcacc tcgtactggt acacgtccgt
    19441 tccgcgcgcg acgctgctgt ggtggccgct gtggatcggc ctggcggcgg tgagcctgcg
    19501 gcggccgtgg ttcacgacgg cgtacctgtg cgtggccgcg ccggtgacga cgatcgtcgc
    19561 gctgacgttc ctgacgggga ggtgggcggg gtgagggcat gtgtgtgtac gtgtacacgt
    19621 acgtcggtgg gtgaggcggt gctcaatacc cacccctact gtccaccggc agggcgagtg
    19681 cggcccgatt tttcgcatcc tgacgctgtt cctgccgctg cggtcgacgt tcgcatcgtc
    19741 ggccgttggt gaaagacagg cggattcagc ggcacgatct cccgcgcgaa gaactccgag
    19801 aactcctcac cccggacagg gcctcgaact cctgggtcgt tgtccggacc tggtcggggt
    19861 cggtgaaccg ccgggcccct gcgcccttca gatcgtcgtc gtggatgacg gcgtacatca
    19921 cggaactgcc gaggatgacg acctcgggca catgctcgtc ccgttccagg tcggggattg
    19981 ttccggcgtc cagtacacgg atctcttcgc ccagttccga cctgggccgg aggacgttca
    20041 tctcccactg gaggtacgga gttacggggt ttcagtcccc ggaagcgaag gcttcccagc
    20101 tgggagtgcc cggctccttg aaggtctggc cccgctcaag cttggcgagg aggtggatgt
    20161 cgctcgcgtg gacccggctg aagtcggcga gatagtcggg cctctggagg acttcaccgg
    20221 caccgctgcg gaagcacgcg aacattgacg cgttcattga tgcactcgtt gacgcactca
    20281 ttcagacgta ctcattcatg agggatgtcc gccttcgccg cgatgggcat ccttcggggg
    20341 atgactacga ggcgctcatc gcgactgatg gagacaccat cgggcagacg tgtcccgagg
    20401 gagtcggtga ggtcgcgtcc gatcacggcg atgtcgccgt tctccagctc ccagatatcc
    20461 gggcattcgg gtccggtgct ggtggcgccc agctccagtg ccgactttcc gagacgtctc
    20521 ttgaagccgg tttcaggatc agcttcccag ggtctgccca tgctgccgcc ccctcctccg
    20581 ggtgaacagg ccaacttacc agtgactacc tggtcaagac cggtgtcaag taagggattt
    20641 ggactggtga atggaggtgc gaatgggggc tggtgttcta ccgaggggcg cgtgttcacc
    20701 ctgcggctct gcccggcccc gcgtggagcc tcgcgtgcgc gcaccccggg gccggcgcgt
    20761 gtcagaccac ggcgagccgg tccaccagta gttccaccct cagctcgctg tcctccggcg
    20821 gcagccgtcc cgctcgggtg agggtggcca gcccgtgcag ggacgcccag aacagttcgg
    20881 tgaacagtgc tgggtgaacg tcgtccccgg ccacctcgcc gagggtttcc aggagggcgg
    20941 cgaaggcgtc cttcagtggc tcgggggtgt cctcctgcgc gaacgccagg ccgccgtcga
    21001 gctggaacat ggcgtcgtag accgccgggt tgtctgcggc gaaatcgagg taggcgcggg
    21061 cgagggcgac gacccgggcg cgaggctcgg ccgtggccgt ggccgtggcc gaggtcgcgg
    21121 cccgcagcgc cccggccatc tcggcggcgc cttcgagggc gacggcgccg atgatctcgc
    21181 gcttgccccg gaagtggctg tagaggacgg gctggctgta ttcgatgcgc tcggcgagcc
    21241 ggcgggtggt gaccgcgtcc cagccctgct gctcggcgag ttcgcgggcc gtcgccacga
    21301 tgagccgctc gcggctcgct cgttcgcgct ccttgcgttc ctgtaccgac atgcttcgat
    21361 cctagcaccg ctagacaatc gagcggcagt aggtctagcg ttgcctcatc acctagcgcc
    21421 gctagatttc aggaggggtc atcatgctca acgcactgga gatcgtcacc accgtgatcg
    21481 tcggactgct ggtgggggtg gagttctccg tcgccttcgt catcaaccgg atcctctacg
    21541 cgctgcccga cgacagcact cagctcggcc gaagccacgg gggccggatg ctgggggcgg
    21601 tgatgccgtt ctggtacatc ggctcgatgg tcctgagcgc gatctgggcc atagccggat
    21661 gggggcagga gggcatcggc ctggtcgtca ccgcgggtgg gctgctgctt gtgagcgtgg
    21721 tcatgtcgat cctgctgctc gtcccgatca acaacctggg caagacgtgg accccggaga
    21781 accggcccgc ggactggaag gagcagatga accgctggga ccggtaccac tacatccggg
    21841 tcgctgtcct gatcgccgcc ttcacgctgc tggtcgcggc gctggtatga gccagggggc
    21901 ggggacaagc gggactgtcc ccgcacgcac ggcgaccggg aggtgttggc cgcgatcgtc
    21961 ttcgtggccc tgtcgggttg cgcctggcag cagctgcctt cggtgtcctt cggcccgtcc
    22021 gtggtcgtcg acgagcagtg aaccgttcgc gcatgccggc ccactgctcc cggcactctg
    22081 tgatcgggag tgacgggccg atatcgtgaa gagcgacgag aggggcgtca agacgcccgg
    22141 ctctgcctcc cacaggggtg gactggccgc agcgcgaagc tgaactccgc accgcgacga
    22201 tgcgatgttc ctccaggaga cggtagacgg tgggggaagt gcgatggatc cgagagcttg
    22261 gacgtgctgc accgattcgc aagacctgcc ctggtgggcg tggctcgtcg tcggcggatg
    22321 cgtcggtgct ctcctgatct tcatcctcac gcgcgtcatg atcgttcacc ggagcgggac
    22381 gacccgtgaa cctttgccca ggctcgccgc tgagcccgtt cccgcggtag tgcaggccat
    22441 ccatcccgcg ccgcttcccg tgtggaaccg tcggcacacc tcacccatgg gcaggctcct
    22501 cgactggtat cgaggtcttg cgcctgcggc ggcgcacgag gcgtatgtgc gctcgctgat
    22561 ccacgatgcc tggttggtcg aggtcgaata cgccacggag gcgggtgagc ggatcagggc
    22621 ctgtctcgcc gatgtgatcc cgggcagcga gctgccgcgt ttcacggtcg gtgccgaggt
    22681 ctccgtgcgg tgcttcgaga accctcggac ccgactgcgc gcagacgcag taccgggtgc
    22741 ccgggcgacg atgcggtgcc tgctcgcaga ttcactcacc gacgtgccgc gcgcgggcta
    22801 cgacctcgac ggggtgcgtg cccgcgtcga gcgcgtgcga tggtc
//
