LOCUS       NZ_CP079114            26312 bp    DNA     linear   CON 06-SEP-2024
DEFINITION  Streptomyces sp. WY228 chromosome.
ACCESSION   NZ_CP079114
VERSION     NZ_CP079114.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. WY228
  ORGANISM  Streptomyces sp. WY228
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8286721)
  AUTHORS   Qin,S.
  TITLE     Volatile organic compounds produced by endophyte Streptomyces sp.
            WY228 mediate plant growth and salt stress tolerance by activating
            hormonal signaling and anthocyanin biosynthesis,
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 8286721)
  AUTHORS   Qin,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUL-2021) Key lab of biotechnology of medicinal
            plants, Jiangsu Normal University, No. 101 Shanghai Road, Xuzhou
            221116, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Canu v. 1.5
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 100.0x
            Sequencing Technology             :: Oxford Nanopore
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_019287315.1-RS_2024_09_06
            Annotation Date                   :: 09/06/2024 06:02:41
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,303
            CDSs (total)                      :: 7,213
            Genes (coding)                    :: 7,059
            CDSs (with protein)               :: 7,059
            Genes (RNA)                       :: 90
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 155
            CDSs (without protein)            :: 154
            Pseudo Genes (ambiguous residues) :: 0 of 155
            Pseudo Genes (frameshifted)       :: 83 of 155
            Pseudo Genes (incomplete)         :: 99 of 155
            Pseudo Genes (internal stop)      :: 10 of 155
            Pseudo Genes (multiple problems)  :: 36 of 155
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 03:35:29
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 4419584
            Orig. end                         :: 4445896
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP079114.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..26312
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-ii"
                     /region_number="16"
                     /rules="cds(LANC_like and DUF4135)"
                     /tool="antismash"
     cand_cluster    1..26312
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..26312
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:16312](-)"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..16312)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     gene            complement(39..629)
                     /locus_tag="KV381_RS19355"
                     /old_locus_tag="KV381_19355"
     CDS             complement(39..629)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003967632.1"
                     /locus_tag="KV381_RS19355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_19355"
                     /product="ATP/GTP-binding protein"
                     /protein_id="WP_086779391.1"
                     /transl_table=11
                     /translation="MDSKSGSAESIYVPDAVQRAAKILVVGHFAVGKTTLIGTLSEITP
                     LRTEERMTQAAAQVDDLRGAPDKKTTTVALDFGRLTLSDELVLYLFGTPGQQRFVELWE
                     DMARGSLGALLLVDPARLADTFPVIDLVETYGLEYAVAVNSFDPYSQHAENELREALDL
                     LPDTPVVFCDARDQKSSAQALITLVRHLLSHVA"
     gene            complement(604..978)
                     /locus_tag="KV381_RS19360"
                     /old_locus_tag="KV381_19360"
     CDS             complement(604..978)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003967631.1"
                     /locus_tag="KV381_RS19360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_19360"
                     /product="DUF742 domain-containing protein"
                     /protein_id="WP_030075678.1"
                     /transl_table=11
                     /translation="MTAPGEEQQVSSGFVRSYVITGGRGLPDAEDLSLVTLVTLAPESQ
                     PPPNPSPEVKAIWELCSGGYLSVAEVAGHLGLPVGVARLLLQDLNQQGHLLRRKAPPPA
                     QLVDRKILEEVLHGLQVRFG"
     misc_feature    complement(712..714)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(975..1379)
                     /locus_tag="KV381_RS19365"
                     /old_locus_tag="KV381_19365"
     CDS             complement(975..1379)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010063113.1"
                     /locus_tag="KV381_RS19365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_19365"
                     /product="roadblock/LC7 domain-containing protein"
                     /protein_id="WP_030075680.1"
                     /transl_table=11
                     /translation="MNPDLSWVLNDLLQVPGARHAILVSADGLLLANSSEIGRDDAETV
                     AAAMSSMQSLSRAVAPFIGTRDPGHWRQTLLEYEDGWIFLIAAGTGAYLAATAAADVDM
                     EAMSFRMQQQVTALGKAMTTPPRRHADSEI"
     gene            complement(1376..2614)
                     /locus_tag="KV381_RS19370"
                     /old_locus_tag="KV381_19370"
     CDS             complement(1376..2614)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018960848.1"
                     /locus_tag="KV381_RS19370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_19370"
                     /product="ATP-binding protein"
                     /protein_id="WP_086779392.1"
                     /transl_table=11
                     /translation="MTFPQGPVIWALVVVALVAVGAVLRARATNVKLRRHNSDLRGERD
                     ALLRQRDELHVVHNGLLQRQSAELAEVRKDAEEETKAVLKAAVRTLQGLADEQQVVIEK
                     AQRKYGDDPGILSDLMAMDHANSQFGRRAQGIAVLCGGWLGRRETVASVFDVARSAQGR
                     IRHFDRVRVNGQVNFSVVSRAVEPVAVVLAELLANATNYSAPGTPVEINIQAVPTGVCL
                     IVDDAGLGMGQEEKDRAAALLSPQAAISVSSLGIPPQFGFAVSGMLAARYGFRVSVDSV
                     SPYGGVRAVVLIPDELLTTEAPPAAAPVEAPEAIAPQPQRVDHRQAAPAPAPTPLFPPA
                     PQPDTATQPLAQITTTAGGLPKRRRKSPVSAVPSAEPQPVRSNEETASRLGAFQRGTRS
                     GRDTTTTEGPEFQ"
     CDS             2648..2794
                     /gene="allorf_4422232_4422378"
                     /locus_tag="allorf_4422232_4422378"
                     /protein_id="allorf_4422232_4422378"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MTPRHAARSQGSFATTVRRFGRCPSEGGAEEFIPPGMPPYAISPL
                     EVR"
     CDS_motif       2648..2683
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MTPRHAARSQGS"
                     /locus_tag="allorf_4422232_4422378_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       2684..2794
                     /prepeptide="core"
                     /locus_tag="allorf_4422232_4422378_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-5.40"
                     /molecular_weight="3864.4"
                     /monoisotopic_mass="3862.0"
                     /core_sequence="FATTVRRFGRCPSEGGAEEFIPPGMPPYAISPLEVR"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MTPRHAARSQGS"
                     /leader_location="[2647:2683](+)"
                     /alternative_weights="3882.4"
                     /alternative_weights="3900.4"
                     /alternative_weights="3918.5"
     misc_feature    complement(2786..2803)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 14.29"
                     /tool="antismash"
     misc_feature    complement(2800..2820)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 20.98"
                     /tool="antismash"
     misc_feature    complement(2858..2872)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 19.16"
                     /tool="antismash"
     gene            3092..3742
                     /locus_tag="KV381_RS19375"
                     /old_locus_tag="KV381_19375"
     CDS             3092..3742
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010071485.1"
                     /locus_tag="KV381_RS19375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_19375"
                     /product="response regulator transcription factor"
                     /protein_id="WP_103538932.1"
                     /transl_table=11
                     /translation="MIRVAVVDDEQLVRSGLKLILGAAPDIEVVACCDGADAVDRVREA
                     RPDVLLLDIRMPEVDGLTVLRQVGALTAPPAVAMLTTFDAGRHIDDALRSGAVGLLMKN
                     TAPEQLVHAVRVLAAGGRILAPEAVGPVIEGYLAAGRDTGAADRTGALTDREGQVLALV
                     GAGLSNREIARELRLSHGTVKDHVSSVLSKLGGVNRVQAAVLADRAGLIDGVS"
     misc_feature    3389..3391
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            3739..4965
                     /locus_tag="KV381_RS19380"
                     /old_locus_tag="KV381_19380"
     CDS             3739..4965
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006126209.1"
                     /locus_tag="KV381_RS19380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_19380"
                     /product="sensor histidine kinase"
                     /protein_id="WP_256995104.1"
                     /transl_table=11
                     /translation="MKRLRPRIPARLSGPRFSGPRLSRPGLTRLGPSRPLLRPGSRRAR
                     AVGRAAVPVGIAVVDGLLVNGFGPGPGLWVALVAAGALVLRRRCPEVPLLVGLPGMYVG
                     QLAFAPLIALYCLADRRRSVAVGAVGAAAVALAQFLPYPVTGLRELALDRETLIMAMDS
                     CVLAVGALVLGRTARVRRERQRELAEGREREHRLLAERTLSTERAWLAREMHDVVAHQV
                     SLIGLQAGALQVGEPDAATVRSTAGVVRELSVKTLTELQHMVGVLRAAGVAAPGLAPQP
                     RLTDLPALVRDCGLRVTLDAPDGPGHWSQAAERAAYRTVQEALTNVRKHAPGAEVDIRV
                     RPLDGGLRVDVRNTAADGSTAPLGLPGGGHGLIGLRERAHLLDGTFDAGPEPDGGFRIQ
                     AVFPSRQTF"
     misc_feature    5064..5078
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.12"
                     /tool="antismash"
     gene            5228..5863
                     /locus_tag="KV381_RS19385"
                     /old_locus_tag="KV381_19385"
     CDS             5228..5863
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF012422.5"
                     /locus_tag="KV381_RS19385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_19385"
                     /product="response regulator transcription factor"
                     /protein_id="WP_078611007.1"
                     /transl_table=11
                     /translation="MADDCIAVGLMVARLSLRRRLTRLFAHRGWNAVACEGAGGLLSSD
                     VPSDVLVVDIDRLDEIRDAAPVVALTYGSEIRHLGAVKADVRAVVDRDDLDEAFLEAVQ
                     EVAAGHGWISPTLVRPLLRGQPSAPAGAVRPTAVAGQPHRPGRPHDPALTAREYEVVSL
                     VSKGMNNSEIAGALYIAESTVKFHMSNILQKTGFRNRGQLVARMPVAG"
     gene            5895..6080
                     /locus_tag="KV381_RS19390"
                     /old_locus_tag="KV381_19390"
     CDS             5895..6080
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006126210.1"
                     /locus_tag="KV381_RS19390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_19390"
                     /product="hypothetical protein"
                     /protein_id="WP_230543432.1"
                     /transl_table=11
                     /translation="MGKKKEALRWAPVAILLVLALIAPLFGDNPTGVVIPLLLAVMLAG
                     VNVTMQKKERSARGAE"
     gene            complement(6171..7061)
                     /locus_tag="KV381_RS19395"
                     /old_locus_tag="KV381_19395"
     CDS             complement(6171..7061)
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024141.5"
                     /locus_tag="KV381_RS19395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_19395"
                     /product="ABC transporter permease"
                     /protein_id="WP_218785814.1"
                     /transl_table=11
                     /translation="MSTGAGMSADTRTGTGTVARADRGASAATATGAVSTADLLRSEVL
                     KLTTTRLWWILLLAVVACSAGFTALIVFGGLNAPRSPLSFGTAGDAVPAYNLAVALAYV
                     FPLAIGVIAVTQEYHARTISATLLAEPRRARVYGAKLLVGLGTAFVYGTVAVVSGALVA
                     AALLSGHGKPAYLTDGTVLGALGGSIVVMTLWGAIGVGVGALVRNQVAAIVGILLVTQF
                     LEPTLRILASSLGNAELGNLLPGGAGDLAGGGTIMTAAAEADGGSQGLGFLVLTLYAVA
                     IGAVGAVRFTRYEAS"
     gene            complement(7058..7816)
                     /locus_tag="KV381_RS19400"
                     /old_locus_tag="KV381_19400"
     CDS             complement(7058..7816)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016641113.1"
                     /locus_tag="KV381_RS19400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_19400"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_218785816.1"
                     /transl_table=11
                     /translation="MAQHAQDAQDAQRQQVISVRDLRKEFKGTTAVDGVSFDVRPGRVT
                     GFLGPNGAGKTTTLRMILGLIRPTGGSALLWGSPYAGLAAPTRRIGVGLDGGAFVGRRT
                     GRGQLRCYAPAAGCGPERVGQLLADVGLSGAADRPVAGYSTGMKQRLSLASALLGDPEL
                     LVLDEPANGLDPEGMLWLREFLRDFAASGRTVLLSSHLLGELEQTVDDVLLMHHGRLLS
                     SGPLDGLLEPGERLESAFLRLTRAGNGVRA"
     gene            complement(7836..10001)
                     /locus_tag="KV381_RS19405"
                     /old_locus_tag="KV381_19405"
     CDS             complement(7836..10001)
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012869.5"
                     /locus_tag="KV381_RS19405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_19405"
                     /product="peptidase domain-containing ABC transporter"
                     /protein_id="WP_218785818.1"
                     /sec_met_domain="Peptidase_C39 (E-value: 7.5e-32, bitscore:
                     108.7, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAWRMRRVRRVREVQQFAQAECGLCCIAMILSAYGSRDSVAGLRR
                     EHEVGRDGLTIKQIAAILRGRGFEVRAFRAGAQRLGQLRLPLIAYWDDSHVVVVEEIDE
                     HRVTVVDPGGGRRTYPAEEFAEHYSGLALEAVPTPDHRPERHREPSVWREFLRSLTGAR
                     KPLVQAFLMSLVLYSFTIFMPIATQYAVNDYAGYLEKAPIALVLVAFTAPMAVFFLLSL
                     LRTVALASVIRSLGEAMMGKTFRRLLELPYKYFANRSQGELFYRLSSITSVRDMISSQL
                     SVVLLDLGSLIAIFSYMFYRSFTLGATAFAVFLTMLAVAVATYRPIRRITEREISETTK
                     SSSLQMEALSSIETLKVSGMTGTFFQDWRQVYAAGMEQTRRRIVLQGVATSGYAVFQVF
                     GPLLVLAVGLWLVLNGSLDLGSAVAAQTLTATSLGMVMSLSGAFTQLITANAQVARVGD
                     ILHQPEDPGAFGDRQVTVRGAVRLRNVGFSYPGSGVPALADVSFDVRPGERVAIVGSSG
                     SGKSTLGKLLMGLYPIRSGDVLYDGVSIGEIDADTFYRSAAYVPQDIVLSNRSIADNIR
                     FGVPEATMEAVVDAARQAHVHDDIAAMPLGYHTPVREMGGSLSGGQRQRIALARALARR
                     PRVLVLDEATSALDTVTESRIAAALDRLECTRIIIAHRLSTIVNADLVVVLEHGRVVQT
                     GRHEELITEPGPYRDLVRSQVDLNTVR"
     gene            complement(10001..12883)
                     /gene="lanM"
                     /locus_tag="KV381_RS19410"
                     /old_locus_tag="KV381_19410"
     CDS             complement(10001..12883)
                     /GO_process="GO:0009403 - toxin biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0018193 - peptidyl-amino acid modification
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="lanM"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR03897.1"
                     /locus_tag="KV381_RS19410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_19410"
                     /product="type 2 lanthipeptide synthetase LanM"
                     /protein_id="WP_218785819.1"
                     /sec_met_domain="DUF4135 (E-value: 7.9e-67, bitscore:
                     224.7, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 1.5e-15, bitscore:
                     55.6, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQLSDAFLDDLVQRITDERSDVFGAFYAPYLRDGAQRIAGLAAAL
                     QSPDTTDDQAGLAGLADLAGVAESALRSLMGLCVETGVRTLIASFRAQDTGYEAFHARL
                     AQAPGREAVLDRFPELDRLLRLATARTARTVADVLHAAVADRAELDALLGGPGRIVSVT
                     PGLGDAHRGGRTVCLVVRDDGSRAVYKPQQDNCQQLLTSLRTLLDADGSFFGPLHPRTL
                     VRPAHVWQEFVVHADLDGTPEHSARYFRRFGRSAALLSMLGATDLHHENIIATPDGPVV
                     IDTETLVSLPNIAPGQARSAPAAASLNLDIERSVLNTLLFPARYAGAKLDVDISGIGCV
                     RPGASEHLQSYLVVDAGTDDIRFDRSQVVVEHGANMATVAGDPLDPRRWTDELVAGFRE
                     ARTLLAAHRDAVEAAVRDSAGWAVRQVVRPTYIYARFLEASTHPVHLGSRQDRAELLGK
                     LPRHYRGTAAESADAVHREEVAALLDLDVPFFTVDCDSGLLRGDFDEEIRSAAQLTPRE
                     SALAAVRSFFTRPADRDPLYLRYALAGSADDVWERREPVSGPAPAASPVHLADPAGWHA
                     LLRDLVVGGADAPTWLTPRLRGDGLRLGGVDATLYDGGGLLLHLAQSAARTGVSPIGVD
                     LERVCASAVHGRPAVLDGTPLPMSPFTGVLSDLVTDWEIRRLTSPDARFRAGDEHVRFR
                     PAQGAFNVDRLSAADFDHLNGYGGYLVHLAAHTEHGATEVTGAGAERLLRRLVTVDGDP
                     AAHRDGEELGLAHGRFGRIAALSAMVTAGLDGDSGARTHLERFAEAYGRHRWQDAGLRD
                     RGNGTGNGGWCKGYAGLAYAHAALLTALGEPAGRIADAVAPEIDRVLEPTGSARDITTA
                     PDLSLCHGLAGRIAVLCHLADLLHRPDLRDAAAALHTAFLDRYGNGGWSCGIGTEPLLP
                     SYFLGLSGWFAAQAMLDHPGTGLPRCLGGR"
     gene            complement(12982..13182)
                     /locus_tag="KV381_RS19415"
                     /old_locus_tag="KV381_19415"
     CDS             complement(12982..13182)
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF038161.1"
                     /locus_tag="KV381_RS19415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_19415"
                     /product="class II lanthipeptide, LchA2/BrtA2 family"
                     /protein_id="WP_030627248.1"
                     /transl_table=11
                     /translation="MGDIAMNDATGYVSADELVELADAPESLAAGFTPTIIPATAVTTV
                     IVGASAAMQGGCPTSGCTKRC"
     CDS_motif       complement(13111..13182)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MGDIAMNDATGYVSADELVELADA"
                     /locus_tag="KV381_RS19415_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(12982..13110)
                     /prepeptide="core"
                     /locus_tag="KV381_RS19415_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-3.80"
                     /molecular_weight="3857.5"
                     /monoisotopic_mass="3855.0"
                     /core_sequence="PESLAAGFTPTIIPATAVTTVIVGASAAMQGGCPTSGCTKRC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MGDIAMNDATGYVSADELVELADA"
                     /leader_location="[13110:13182](-)"
                     /alternative_weights="3875.5"
                     /alternative_weights="3893.5"
                     /alternative_weights="3911.5"
                     /alternative_weights="3929.5"
                     /alternative_weights="3947.6"
                     /alternative_weights="3965.6"
                     /alternative_weights="3983.6"
     gene            complement(13283..16312)
                     /locus_tag="KV381_RS19420"
                     /old_locus_tag="KV381_19420"
     CDS             complement(13283..16312)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR03897.1"
                     /locus_tag="KV381_RS19420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_19420"
                     /product="type 2 lanthipeptide synthetase LanM family
                     protein"
                     /protein_id="WP_218785821.1"
                     /sec_met_domain="DUF4135 (E-value: 1.1e-64, bitscore:
                     217.7, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 1.6e-34, bitscore:
                     118.0, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNSHDVSPGIAEALRTYLPELTDPELIAHVEERLRAAATEDEGEQ
                     DQELPDPPPAYDPSLDPDGLFHDYFRHFVAPWSGRVRHAAAQSPTIAAPQRIVDDFVTH
                     QTGLVSRLMIRTLVEELHRRRTAGLLDGETPEERYAAFRRWTNSPAGHAELTARYPHLF
                     FLVGRQVEASARYVVEIIEEIGSAAPQLGSLLAGGPEHPRVDRLVLGEGDTHNGGRSVA
                     QVLFTDGRRVLYKPHPIGAEAGYSSFVSWMNGRLGTDLPTVAVVPTEHGGFVEFIPTEE
                     YAGEQKDYFARIGTLAGILFLLRATDIHFENMVSCAAGPVVIDTETLLSPRLNLPEAYD
                     DGAASKAGALTLRESIIGSGLLPLVVRSGDDDHGMDIGAIGYDTGQRSPYKSLSLQNPG
                     RDDMFVGMVTTTTTAANANLAVQRATQLPVNDQRDIVKREFGRVLRYAADHPDAVVDAV
                     EEFLGDVQFRHVNQATIFYTQLLRMATHPHAMADPVVRAAVLNRVVLRTGDSPAIADAE
                     VRQMARGDVPYFSYTARSRALGSTDGAVRADALAEPPLTTVRERIHGLDESVIERELRL
                     IDFSFVNKLPTDQEETGFVPVRPAGKPAVAVDRGRFVDEAVRIGERLLATRVASTEPHH
                     PATWIAPQVTTDSQSQWSPGTLGYDLYGGSPGPALVLAALARETGRADFAAAARSVLDL
                     VEEQLRGGQLAEQGVSVGGMTGMAGTAYALVVARGLLDEPDAGRLGELARELARCSGAE
                     AGTDFLSGMAGALAVGLALHERATDPAERAVVAEAVRTIAARETEALGGIGLADPRVTP
                     YTGYAHGAMGIAPVLLRYGAEFGDPGVHGLGLRILGAVLDAQEDGDRDWPRVWGEPERS
                     YGWCHGAPGMLLGALMSNEHAPGAVPRPVLDRLAGLTLDRGFGNNPTYCHGDLACAEIV
                     RLGQDLVPGLFGEAARTGDGGGLDDLYPRLFDEVVERYGQRSDTKYAYTNSLMVGEAGL
                     AWSVLRHLDPGSHPSLLRFA"
     misc_feature    16409..16425
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 15.51"
                     /tool="antismash"
     gene            complement(16420..16605)
                     /locus_tag="KV381_RS19425"
                     /old_locus_tag="KV381_19425"
     CDS             complement(16420..16605)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) mature_ha"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF000539.0"
                     /locus_tag="KV381_RS19425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_19425"
                     /product="plantaricin C family lantibiotic"
                     /protein_id="WP_030075698.1"
                     /sec_met_domain="mature_ha (E-value: 5.1e-08, bitscore:
                     31.2, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MANPNVGILEEIDDQNLDAVSAAGQGWGTIVSSLSCYGASYVLGN
                     NGNFCTATAECQNNCK"
     CDS_motif       complement(16537..16605)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MANPNVGILEEIDDQNLDAVSAA"
                     /locus_tag="KV381_RS19425_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(16420..16536)
                     /prepeptide="core"
                     /locus_tag="KV381_RS19425_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-2.30"
                     /molecular_weight="3793.1"
                     /monoisotopic_mass="3790.7"
                     /core_sequence="GQGWGTIVSSLSCYGASYVLGNNGNFCTATAECQNNCK"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MANPNVGILEEIDDQNLDAVSAA"
                     /leader_location="[16536:16605](-)"
                     /alternative_weights="3811.2"
                     /alternative_weights="3829.2"
                     /alternative_weights="3847.2"
     gene            complement(16797..17831)
                     /locus_tag="KV381_RS19430"
                     /old_locus_tag="KV381_19430"
     CDS             complement(16797..17831)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1078: LacI family
                     transcription regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018514047.1"
                     /locus_tag="KV381_RS19430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_19430"
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="WP_218785822.1"
                     /transl_table=11
                     /translation="MTSRTVTLLDVARAAGVSKSTVSDALQGSGRVAGATRDRVRAVAE
                     ELGYRPNSAARRLRRASTGAVGLHLPATATRLDYYMNLAFGAVERAQEDGLDLVLLAPS
                     GASGGRIASRVDGLLVIDPEAGDSAVPGLLDAGVPVVTGERYLGPAAAPSGAVVCDNAA
                     SLTALLDHVAERGARRPAVLAPSGSSAWATALRATARSWGLAHGVEMALRTVPFAATPA
                     EAEETTRALLTADPAVDAVICAPDGSAPGVLRAAAALGREVGDSEKAGGSGKSGSGLLV
                     AACVDGPATRNAEPPVTAVDLRPAAYGRACAELLCDILADRAAPDTVRRHAWSLETRAS
                     TGPA"
     misc_feature    complement(17896..17909)
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: strong, score: 24.53"
                     /tool="antismash"
     gene            17976..18920
                     /locus_tag="KV381_RS19435"
                     /old_locus_tag="KV381_19435"
     CDS             17976..18920
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1294: Nitrilase/cyanide hydratase and apolipoprotein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003983325.1"
                     /locus_tag="KV381_RS19435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_19435"
                     /product="carbon-nitrogen hydrolase"
                     /protein_id="WP_218785823.1"
                     /transl_table=11
                     /translation="MRLITAYNPPASPTRTRPAERAPLRVAAVQQRWHRDPAEHRAALL
                     EGIRLAAAEGARVVCLQELTLSPYFAVVRRADHPAPAAPEELLTGPTFTFAAEAAREHG
                     VYVHASLYEKAPAAGGEDDGLGYNTAILVAPDGTLAQRTRKTHIPVTEGYYEDDWFRAG
                     PAGDDAFPLVTVDEARFGLPTCWDQWFPELARAYSLAGADVLVYPTAIGSEPGFPGFDS
                     QPLWQKVITGNAIANATFMIVPNRIGAENGLTFYGSSFIVDPYGRVLAQAPRDEPAVLV
                     ADLDLDARRDWLELFPFLTTRRPDAYGPLTEPR"
     gene            19277..20173
                     /locus_tag="KV381_RS19440"
                     /old_locus_tag="KV381_19440"
     CDS             19277..20173
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010071487.1"
                     /locus_tag="KV381_RS19440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_19440"
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="WP_306438621.1"
                     /transl_table=11
                     /translation="MLAVGAVVWAAVTALHASIPNTGVNAGSLFQTLLPWTGLGVPFLL
                     VLAAVLRSRLVAVAVLAPAVVWVTLFGGALTDKRSGGGDLTVVSHNVDEANTDPAGTAR
                     VLAGAGADVLALEELSDASAPVYSRELASAYPHHAVLGGVGIWSRHPLADVKEVPIMPW
                     TRAMRATVRAPDGPPVAVYAVHLASVRVSAAGFTTGRRNEAARELAAALRAESAHRVVV
                     LGDLNGTYRDRALAPVTSQLRSAQGEAGAGLGFTWPAAFPMARIDDVLVRGLTPRAAWT
                     LPATGSDHLPVAATLTR"
     gene            20307..21059
                     /gene="cseB"
                     /locus_tag="KV381_RS19445"
                     /old_locus_tag="KV381_19445"
     CDS             20307..21059
                     /GO_function="GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA]"
                     /GO_function="GO:0000976 - transcription cis-regulatory
                     region binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene="cseB"
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003967602.1"
                     /locus_tag="KV381_RS19445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_19445"
                     /product="two-component system response regulator CseB"
                     /protein_id="WP_218785824.1"
                     /transl_table=11
                     /translation="MTSNAQVGSVSEARGPAPVSVLVVEDDATIRRAVQLALERYGYRV
                     AVAADGLSGLEAFRAGGHDLLILDVMLPELDGIGLCHRIREESPVPVLMMSARGDALDV
                     VAGLEAGADDYVIKPVDTAVMVARIRALLRRATFRPDPVGRAPKKSDRAPDHVLTFGDL
                     TVDTLGMEVRRAGEPVSLTPTELRLLLEFAAAPGSVLDRRRLLREVWDYGWEGDTRVVD
                     LCVLRLRKKIGSGRIETVRGFGYKLVRG"
     gene            21076..22350
                     /locus_tag="KV381_RS19450"
                     /old_locus_tag="KV381_19450"
     CDS             21076..22350
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018960853.1"
                     /locus_tag="KV381_RS19450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_19450"
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="WP_218785825.1"
                     /transl_table=11
                     /translation="MDFLNPRALRWKIAALVAAACCAVAAVIGFLVHDATRERGLRVGT
                     DRTLTRLIAAEREFDRTGKAPADIDVRTRAELPEPLARDLADVTGDELPGTGRGYATWY
                     DADPPNWHWMWGAVAVGDDRILVVRDDMSTEVRSLQLLDRSIVKSVLAALLFVVPLAAL
                     ATEPINRRLRHGARTARRIADGDLDARIGPAGRARDEITEMSAAVDDMATALQRKLENE
                     RRFTADVAHELRTPLMGLVTAAGLLPESDEAASLVRDRLRALNALVEDLLEISRLDAGA
                     ERARLDPVPLGELVADVVRRTGTETRVSVVDAEVVETDPRRVERIVVNLVANAHRHGAA
                     PVEVTVTGARIAVRDHGPGFPPDLLERGPQRFRTGASERGRGHGLGLTVAQGQAEVLGA
                     RLAFADAPGGGALATLDLAPHARPA"
     gene            22498..23508
                     /locus_tag="KV381_RS19455"
                     /old_locus_tag="KV381_19455"
     CDS             22498..23508
                     /EC_number="3.4.-.-"
                     /GO_function="GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019544744.1"
                     /locus_tag="KV381_RS19455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_19455"
                     /product="D-alanyl-D-alanine carboxypeptidase family
                     protein"
                     /protein_id="WP_256995105.1"
                     /transl_table=11
                     /translation="MQPLPADPTVTPSAGRGARFRRSVLLPLTAAVLLAAGTGGWYAFG
                     GGGPVTGAGGADGPGEGVAPLARSMQLPWPREGQASVAVEGIGSLGTRGEQKPVPIASV
                     TKVMTAYVILKDRPMRADAPGATVVADQRAADESYSSVETTAPVLAGRTYSQRRLLELM
                     MVPSGNNVARLLARWDAGDEKAFVAKMNRTAAALGMRATTYTGVSGMEASTRSTAADQL
                     RLARAAMKDPAFRQIVATGSVTAPGAGVTFRNTNKLLGHDGVIGLKTGSSTPAGGNLVW
                     ATRQEVAGVSRLVIGVVLHQRAGTTPAEGSAAAHEASRALITAIRADLLDAANRA"
     gene            complement(23533..24666)
                     /locus_tag="KV381_RS19460"
                     /old_locus_tag="KV381_19460"
     CDS             complement(23533..24666)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1217: NADH:flavin oxidoreductase/NADH oxidase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014133930.1"
                     /locus_tag="KV381_RS19460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_19460"
                     /product="NADH:flavin oxidoreductase"
                     /protein_id="WP_086777270.1"
                     /transl_table=11
                     /translation="MRDAAEASSAAARAAATLSRPFTVRGLTSRNRIAMAPMTRQFSPD
                     GVPGQDVADYYTRRAAGDVGLIITEGTYVDHESAGTSDRVPRFHGEAALAGWGHVADSV
                     HRAGGAIIPQLWHVGVTRTEGAGPVPDAEPVGPSGLSLSGEPKGRAMTQKDLDDVIAAF
                     ADAAAAAERLGFDGAELHGAHGYLIDQFLWSGSNRRTDAYGGDLVARTRFAAEIVAACR
                     AAVSDAFPLFFRMSQWKSDNYEAKLARTPEELDALLTPLAEAGVDVFHASTRRYWLPEF
                     EGSDLNLAGWVKKISGRPTLTVGSVGLDGDFFSAFQGNDSKVTGIEQLLDRMERDEFDM
                     VAVGRALISDPEWAAKTLGGRTADITPFSAEMLKTLH"
     misc_feature    24706..24721
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: weak, score: 15.49"
                     /tool="antismash"
     CDS             complement(24717..24863)
                     /gene="allorf_4444301_4444447"
                     /locus_tag="allorf_4444301_4444447"
                     /protein_id="allorf_4444301_4444447"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MSRPRRAPEADSVLCPLFTRIEAVAGMAARHECVGAGWTTPAMDR
                     NPT"
     CDS_motif       complement(24783..24863)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MSRPRRAPEADSVLCPLFTRIEAVAGM"
                     /locus_tag="allorf_4444301_4444447_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(24717..24782)
                     /prepeptide="core"
                     /locus_tag="allorf_4444301_4444447_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-1.20"
                     /molecular_weight="2187.4"
                     /monoisotopic_mass="2186.0"
                     /core_sequence="AARHECVGAGWTTPAMDRNPT"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MSRPRRAPEADSVLCPLFTRIEAVAGM"
                     /leader_location="[24782:24863](-)"
                     /alternative_weights="2205.4"
                     /alternative_weights="2223.4"
     misc_feature    complement(24799..24812)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.18"
                     /tool="antismash"
     gene            complement(24860..26119)
                     /locus_tag="KV381_RS19465"
                     /old_locus_tag="KV381_19465"
     CDS             complement(24860..26119)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="KV381_RS19465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="KV381_19465"
                     /product="hypothetical protein"
                     /protein_id="WP_218785826.1"
                     /transl_table=11
                     /translation="MEPRPANRTGTQLEDRLKDWASRHRTWLLVAVGTVVVLLIAGNAM
                     RGPAKDWWLAREACGGQLPSGDLEIVRTDLRLGEAEESFDAEDGTYSCVLRNENGGAVV
                     TVDTYPAGRDRDKVLGSAGTSRPPDAVLPGGLPGFEEDPGIVHLMPECPRGVLSAAEKK
                     EARAEAGEQEKAAPVRRRLLVSTRTYSAHSPAEKAAMLRIAVHMTNAVTEKLGCGGEPL
                     PAPADGAVPDEGTYVPRARAKGTACDALATTRVPEAGRNGDVRIAIADGGIVGRCTLRA
                     TETYPDAREGTSIVELTSWLGDWGPLVHEMGSDPDPLPMGRGAGRRPALTEHRAWAVAR
                     CDGDDVGFAARWGQGYPDRRRKPGSTYVPPTEAETYERSVLLRAYVSAFAADQVRRGAC
                     TDLKLPAKPEKPERSASGRG"
     misc_feature    complement(26254..26269)
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: strong,
                     score: 18.33"
                     /tool="antismash"
ORIGIN
        1 cttccgtata cgtttctggt gcgggcgggc cgcgtgggtc aggccacgtg cgagagcaga
       61 tggcggacca gggtgatcag tgcctgcgcg gaggacttct ggtcccgggc gtcgcagaag
      121 acgaccgggg tgtccggcag caggtcgagc gcctcgcgca gttcgttctc ggcgtgctgg
      181 gagtacgggt cgaagctgtt gacggcgacc gcgtactcca gtccgtacgt ctcgacgagg
      241 tcgatgacgg ggaacgtgtc ggcgagccgc gccgggtcga ccaggagcag ggcgcccagc
      301 gaaccgcgcg ccatgtcctc ccacagctcc acgaaccgct gctggcccgg tgtgccgaac
      361 aggtacagca ccagttcgtc gctgagggtg agccggccga agtccagggc gaccgtggtc
      421 gtcttcttgt cgggggcgcc gcgcagatcg tcgacctggg ccgcggcctg ggtcatccgc
      481 tcctcggtgc gcagcggggt gatctcggac agggtgccga tcagcgtcgt cttgcccacc
      541 gcgaagtgcc cgacgacgag gatcttcgcc gcgcgctgca ccgcgtccgg cacatagatg
      601 ctctcagccg aaccggactt ggagtccatg caacacctct tcgaggatct tcctgtcaac
      661 gagctgggcc ggcggcggcg ccttccggcg cagcaggtgt ccctgctggt ttaagtcctg
      721 gagcagcaga cgggccaccc cgaccggcag gccgaggtgg ccggccacct cggccacgga
      781 cagatagccg ccggagcaca gctcccagat cgccttgacc tccgggctgg ggttcggcgg
      841 cggctggctc tcgggggcga gggtgaccag cgtgaccagc gagaggtctt ccgcgtcggg
      901 cagcccccgt ccgccggtga tgacatagga ccggacgaac ccgctgctga cctgctgctc
      961 ctcgcccggc gcggtcatat ctcgctgtcc gcgtgtcggc ggggaggtgt ggtcatcgcc
     1021 ttccccagcg cggtgacctg ctgctgcatc cggaaggaca tcgcctccat gtccacgtcg
     1081 gcggcggcgg tggcggcgag ataggcgccg gtgccggcgg cgatcaggaa gatccagccg
     1141 tcctcgtact ccaggagcgt ctgccgccag tggcccgggt cgcgggtgcc gatgaagggg
     1201 gcgacggctc ggctgaggga ctgcatggag ctcatcgccg cggcgacggt ctccgcgtcg
     1261 tcccggccga tctcgctgga gttggcgagc aggaggccgt cggcggacac caggatcgcg
     1321 tgccgggcgc cgggcacctg gagcaggtcg ttgagcaccc aggacagatc ggggttcact
     1381 ggaactcggg tccttccgtc gtcgtcgtgt cgcgtccgga ccgggttcct cgctggaacg
     1441 cgccgagtcg ggaggcggtc tcctcgttgc tgcgcacggg ctgcggttcg gccgagggca
     1501 ccgcggagac cgggctcttg cgacgacgct tcggcagccc cccggcggtg gtggtgatct
     1561 gggccagcgg ctgggtcgcg gtgtccggct ggggtgcggg cgggaagagc ggggtgggcg
     1621 ccggggccgg ggcggcctgc cggtggtcca cccgctgcgg ctgcggagcg atggcttcgg
     1681 gcgcttccac gggggccgcg gcgggcggcg cctcggtggt gagcagttcg tcggggatca
     1741 ggaccaccgc gcgtacgcct ccataggggg aaacggagtc caccgagacc cggaagccgt
     1801 agcgggcggc gagcatcccg gagacggcga atccgaactg cggcggaata ccgaggctgg
     1861 agacgctgat cgcggcctgg ggggagagga gggccgccgc gcggtccttc tcctcctggc
     1921 ccatgccgag accggcgtcg tcgacgatga ggcagacacc cgtcggcacg gcctggatgt
     1981 tgatctcgac cggggtgccg ggggcggagt agttcgtggc gttggccagc agctcggcga
     2041 ggaccacggc gacgggctcc acggcccggc tgaccaccga gaagttcacc tggccgttga
     2101 cccggacccg gtcgaagtgc cggatccggc cctgggcgct gcgggccacg tcgaagacgg
     2161 aggccacggt ctcgcgccgg ccgagccagc cgccgcagag cacggcgatg ccctgggcgc
     2221 gccggccgaa ctggctgttg gcgtggtcca tggccatcag gtcggagagg atcccgggat
     2281 cgtcgccgta cttgcgctga gccttctcga tcacgacctg ctgctcgtcg gcgaggccct
     2341 ggagggtacg gacggcggcc ttgaggaccg ccttggtctc ctcctcggcg tccttgcgga
     2401 cctccgcgag ttcggcggac tgacgctgca gcagaccgtt gtggacgacg tggagttcgt
     2461 cccgctggcg caggagcgcg tcgcgctcac cgcgcaggtc ggagttgtgt ctgcgcagct
     2521 tgacgttggt cgcgcgagcc cgcagaacgg cacccacggc gaccagtgct acgacaacca
     2581 gcgcccagat gacggggccc tgtggaaatg tcatgagact cacttcaagt gccatggcgg
     2641 aaacggcttg acaccccgtc atgcggcacg cagccagggc tcgttcgcca cgaccgtgcg
     2701 ccgcttcggg aggtgcccct ccgaaggtgg ggccgaggaa ttcattcctc ccggaatgcc
     2761 cccatacgcc atcagcccac tggaagtaag atgatcttat catcggcagc gcgccgaaat
     2821 gtcaaggccg ccacgccagt tgccactcga cgcaggatgt tcacattgag gagacctggc
     2881 ggacggcgtc ccgctgccgc cggtacgacc ggcagggtcc ggcgggcacg gtcggtgggg
     2941 gtggccgacg ggcgcggccg acgggtgcgg tcggcaggcc tccgaaggta cggaattcaa
     3001 cgttccgctt cttgtccggc gtccctggaa cccgccccgc tcctgccgta cccttcggtg
     3061 attcctggtc ggcagggtga aggggcgcat cgtgattcgg gttgccgtcg tggacgacga
     3121 gcagctggtc cggtccgggc tgaaattgat cttgggtgcc gctccggaca tcgaggtggt
     3181 cgcctgctgc gacggggccg acgccgtcga ccgcgtacgg gaggcgcgcc ccgacgtcct
     3241 gctgctggac atccggatgc ccgaggtcga cgggctgacc gtgctgcggc aggtgggcgc
     3301 gctgacggcg ccgcccgccg tggcgatgct gaccaccttc gacgcgggcc ggcacatcga
     3361 cgacgcgctg cgctcggggg cggtcggttt actgatgaag aacacggccc cggaacagct
     3421 cgtccacgcg gtccgcgtgc tggccgccgg cggccggatc ctggcgcccg aggcggtcgg
     3481 cccggtgatc gagggctatc tcgccgcggg ccgggacacc ggagcggccg accgcaccgg
     3541 ggccctgacc gaccgcgagg gccaggtgct ggcgctggtc ggcgcgggcc tgtccaaccg
     3601 ggagatcgcc cgtgagctgc ggctgtccca cggcacggtg aaggaccacg tcagctcggt
     3661 gctgtccaag ctgggcgggg tcaaccgggt ccaggcggcg gtgctcgcgg accgggccgg
     3721 tctgatcgac ggggtgtcgt gaagcgcctc cgtccccgca taccggcgcg cctctccggt
     3781 ccgcgcttct ccggcccgcg tctctcccgc ccgggtctca cccgccttgg tccctcccgt
     3841 ccgctcctgc gccccggctc ccgccgggcg cgggccgtcg gccgggccgc cgtgccggtc
     3901 gggatcgccg tggtcgacgg cctcctcgtc aacggcttcg gccccgggcc cggcctctgg
     3961 gtcgcgctcg tcgcggcggg cgcgctggtg ctgcgccgcc gctgccccga ggtgccgctg
     4021 ctcgtcgggc tgcccgggat gtacgtcggc cagctggcgt tcgccccgct gatcgcgctg
     4081 tactgcctcg ccgaccgccg ccgcagtgtg gccgtcggag ccgtgggggc cgccgcggtc
     4141 gccctggccc agttcctgcc gtacccggtc accggcctgc gggagctcgc gctggaccgg
     4201 gagaccctga tcatggcgat ggactcctgc gtcctggccg tcggggcgct ggtcctgggg
     4261 cgtacggccc gggtgcgccg cgagcggcag cgggagctgg cggagggccg ggagcgcgag
     4321 caccggctcc tcgccgagag gaccctgtcc accgagcggg cctggctggc gcgcgagatg
     4381 cacgacgtcg tcgcccacca ggtcagcctc atcggcctcc aggccggggc gctccaggtc
     4441 ggcgaaccgg acgccgccac cgtacgctcg accgccgggg tcgtccgcga gctctcggtg
     4501 aagaccctca ccgagctcca gcacatggtg ggcgtcctgc gcgcggccgg tgtcgccgcg
     4561 cccggcctcg ccccgcagcc ccggctcacc gacctgcccg ccctggtccg cgactgcggt
     4621 ctgcgcgtca cgctcgatgc cccggacggc cccggccact ggtcccaggc ggcggagcgg
     4681 gccgcctacc gcacggtcca ggaagccctc accaacgtgc gcaagcacgc ccccggcgcc
     4741 gaggtggaca tccgggtccg gccgctggac ggcggactgc gggtcgacgt ccgcaacacc
     4801 gccgccgacg gctccaccgc acccctcgga ctgcccggcg gcggtcacgg tctgatcggt
     4861 ctgcgggagc gggcgcatct gctcgacggc accttcgacg ccgggcccga gccggacggc
     4921 ggattccgga tccaggccgt gttcccgtcc cggcagactt tctgagggtg tgtccgcacc
     4981 catccgatcc ggatttccgg tccttctcca ggaggagatc cgcaaccccg gaccccgccg
     5041 accggcgggg ggtgcacccg tcgaatggcc ggataattcg gacccacctc ccttaagtgt
     5101 attgctgctt gctgtcattt ccctgggaaa gataggatcg ctgcgcgcct tgaccagcgc
     5161 acgccgtgcg ggggccgtcg tgacggatcc gccctgccgg cggccgtacg ggggaagtag
     5221 ggcagaaatg gcagatgact gtatagccgt agggctgatg gtcgccagat tgtcgttgcg
     5281 gcgaagactg accaggctct tcgcccatcg tggatggaac gccgtcgcgt gcgagggggc
     5341 cggggggctt ctttcgtccg acgtcccgtc cgacgtcctg gtcgtcgaca tcgaccggct
     5401 cgacgagata cgggacgccg cgccggtcgt ggcgctgacc tacggctcgg agatacgtca
     5461 tctcggagcg gtgaaagccg acgtccgggc ggtcgtggac cgcgacgacc tggacgaggc
     5521 cttcctggag gccgtgcagg aggtcgccgc cgggcacggg tggatctcac ccacgctggt
     5581 gcgcccgctg ctgcgcgggc agccgtccgc accggcgggg gccgtccggc cgaccgccgt
     5641 ggccgggcag ccgcacagac cggggcggcc gcacgatccg gccctgacgg cacgggagta
     5701 cgaagtggtc tccctggtgt cgaagggaat gaacaacagc gagatcgccg gtgccctcta
     5761 tatcgcggag agcaccgtga agttccatat gtcgaacatt ctgcagaaga ccggattccg
     5821 taaccgcggt cagctcgtgg cgcgtatgcc ggtggccggc tgaaccggca gtacacaaca
     5881 tggaggagac cgtcatggga aagaagaagg aagccctgcg ctgggcgccg gtggccattc
     5941 tgctggtgct cgcgctgatc gcgccgctgt tcggggacaa tccgaccggc gtcgtgattc
     6001 cgcttctgct cgcggtgatg ctcgcgggcg tcaacgtcac gatgcagaag aaggagcgct
     6061 ccgcccgcgg ggccgagtga tccggccggg ggagcaccac ggatgaatgc cggggccgcc
     6121 gcacctgacc agtgcggcgg ccccggcacg cgtcgttcat gaacgctcgg tcacgaggcc
     6181 tcgtaccggg tgaagcgcac cgcgcccacc gccccgatcg ccaccgcgta cagcgtgagc
     6241 accaggaagc cgaggccctg cgaaccgccg tccgcctccg ccgcggccgt catgatcgtg
     6301 ccgccgcccg ccaggtcgcc cgccccgccg gggagcaggt tgcccagctc cgcgttgccg
     6361 agcgaggagg cgaggatccg caacgtcggc tccaggaact gcgtcaccag caggatgccg
     6421 acgatcgccg ccacctggtt gcgcaccagc gcgcccacgc cgacgccgat cgcgccccac
     6481 agggtcatca ccacgatgct gccgcccagc gcgccgagca ccgtgccgtc cgtgaggtac
     6541 gccggcttcc cgtggcccga gagcagcgcc gccgccacca gggcgccgga gaccaccgcc
     6601 accgtgccgt acacgaacgc cgtgcccagc ccgacgagga gcttggcgcc gtagacccgg
     6661 gcccggcgcg gctcggccag cagcgtcgcg gagatcgtgc gcgcgtggta ctcctgcgtc
     6721 accgcgatca cgccgatggc cagcgggaag acgtacgcga gcgccaccgc caggttgtac
     6781 gcgggtacgg cgtcgcccgc cgtgccgaaa ctcagcggac tgcgcggggc gttgagaccg
     6841 ccgaagacga tcagcgcggt gaagccggcg ctgcacgcga cgaccgcgag cagcaggatc
     6901 caccacagcc gggtggtggt cagcttcagc acctcggacc gcaggagatc ggccgtggag
     6961 accgcgccgg ttgcggtggc cgcgctcgcg ccccggtccg cccgcgccac cgtgcccgta
     7021 cccgtacgcg tatccgcgct catgcccgca cccgtgctca tgcccgtact ccgttcccgg
     7081 cccgtgtcag ccgcaggaaa gccgactcca ggcgctcgcc cggctccagc agaccgtcga
     7141 gagggccgct gctcagcagc cgcccgtgat gcatcagcag gacgtcgtcc accgtctgct
     7201 ccagctcgcc gagcagatgg ctggagagca gcacggtccg gcccgaggcc gcgaagtccc
     7261 gcaggaactc ccgtagccac agcatccctt cgggatccag accgttggcc ggctcgtcca
     7321 ggaccagcag ctccggatcg cccagcagcg ccgacgcgag ggagaggcgc tgcttcatgc
     7381 cggtcgagta cccggcgacc ggccggtccg ccgccccgga caggcccacg tccgccagca
     7441 gttggccgac ccgctccgga ccgcagccgg cggccggggc gtaacagcgc agttggcccc
     7501 ggcccgtgcg gcggccgacg aacgccccgc cgtccaggcc gacgccgatc cgccgtgtgg
     7561 gggcggcgag tccggcgtac gggctgcccc agagcagtgc gctgccaccg gtcgggcgga
     7621 tcagcccgag gatcatgcgc agggtcgtcg tcttgcccgc gccgttgggg ccgaggaagc
     7681 cggtgacccg gccgggccgt acgtcgaagg agactccgtc gacggctgtc gtgcccttga
     7741 actccttccg gagatcccgg accgagatca cctgctgtcg ctgtgcgtcc tgtgcgtcct
     7801 gtgcgtgttg tgccatgcgt cggctcctcc ttctcttatc ggaccgtgtt gaggtcgacc
     7861 tgggagcgga ccaggtcccg gtacggaccg ggctcggtga tcagctcctc gtggcggccg
     7921 gtctggacga cccggccgtg ttccagcacc accacgagat cggcgttcac gatggtcgac
     7981 agccggtggg cgatgatgat ccgcgtgcac tccagccggt ccagcgcggc ggcgatccgg
     8041 gactcggtga cggtgtccag cgcgctggtc gcctcgtcga gcacgaggac gcggggcctg
     8101 cgggcgagcg cgcgggcgag cgcgatccgc tggcgctggc cgccggagag gctgccgccc
     8161 atctcgcgga ccggcgtgtg gtagcccagc ggcatcgccg cgatgtcgtc gtgcacatgc
     8221 gcctggcgcg cggcgtcgac gaccgcctcc atcgtggcct cgggcacccc gaagcggatg
     8281 ttgtccgcga tgctgcggtt gctgaggacg atgtcctgcg ggacgtacgc ggcgctccgg
     8341 tagaacgtgt cggcgtcgat ctcgccgatc gacaccccgt cgtagaggac gtcaccggac
     8401 cggatcgggt acagccccat gaggagcttg cccagcgtgc tcttgcccga gcccgaactg
     8461 cccacgatcg cgacccgttc gccgggccgg acgtcgaacg agacgtccgc cagggccggg
     8521 acaccggagc cgggatagga gaagcccacg ttccgcagcc gcaccgcgcc ccgcacggtg
     8581 acctgccggt cgccgaacgc ccccgggtcc tcgggctggt ggaggatgtc gccgacccgt
     8641 gccacctgcg cgttcgccgt gatcagctgg gtgaacgcgc cggacagcga catcaccatg
     8701 ccgaggctcg tcgcggtcag ggtctgcgcc gccaccgccg aaccgaggtc gagcgagccg
     8761 ttcagcacca gccacagccc caccgccagc accagcagcg gcccgaacac ctggaacacc
     8821 gcgtaaccgc tggtcgccac gccctggagg acgatccgcc gccgggtctg ctccatcccc
     8881 gccgcgtaga cctgccgcca gtcctggaag aacgtgccgg tcatcccgga gaccttcagc
     8941 gtctcgatcg aggacagcgc ctccatctgg agcgacgagg acttcgtcgt ctcgctgatc
     9001 tcccgctcgg tgatccgccg gatcggccgg tacgtcgcca cggccaccgc gagcatggtc
     9061 aggaagaccg cgaacgccgt cgcaccgagg gtgaacgagc ggtagaacat gtagctgaag
     9121 atcgcgatca ggctgccgag gtcgagcagc acgaccgaca actggctgga gatcatgtcc
     9181 cgtacggacg tgatgctgga gagccggtag aacagctcgc cctgcgagcg gttggcgaag
     9241 tacttgtagg gcagttccag cagccgccgg aacgtcttcc ccatcatcgc ctcgcccagg
     9301 ctccggatca cggacgccag cgcgacggtt ctgagcagcg agagcaggaa gaacaccgcc
     9361 atcggggcgg tgaacgccac caggacgagg gcgatcgggg ccttctccag atagcccgcg
     9421 tagtcgttga ccgcgtactg ggtggcgatc ggcatgaaga tggtgaagga gtacagcacc
     9481 aacgacatca ggaacgcctg gaccagcggc ttccgggccc cggtcagcga gcgcaggaac
     9541 tcccgccaga cgctgggctc gcggtgccgt tcgggccggt ggtccggcgt cggtacggct
     9601 tcgagcgcga ggcccgagta gtgctcggcg aactcctccg ccgggtacgt gcgccggccg
     9661 ccgcccgggt cgacgacggt cacccggtgc tcgtcgatct cctcgacgac cacgacatgg
     9721 ctgtcgtccc agtacgcgat gagcggcagc cgcagctgtc cgagccgctg cgccccggcg
     9781 cggaacgccc gcacctcgaa gccccggccg cgcaggatgg ccgcgatctg cttgatggtg
     9841 aggccgtcgc gccccacctc gtgctcgcgg cgcagcccgg ccaccgaatc gcgggagccg
     9901 tacgccgaga ggatcatcgc gatgcagcac aggccgcact cggcctgggc gaactgctgg
     9961 acctcgcgga cccgtcggac cctgcgcata cgccatgcca tcagcggcct ccgaggcagc
    10021 ggggaaggcc ggttccgggg tggtcgagca tcgcctgggc ggcgaaccag ccggagaggc
    10081 cgaggaaata ggacggcaga aggggttcgg tgccgatccc gcaggaccag ccgccgtttc
    10141 cgtaccggtc gaggaacgcg gtgtgcagcg cggcggccgc gtcgcgcagg tcggggcggt
    10201 ggagcaggtc cgccagatgg cacaggaccg cgatccggcc ggcgagaccg tggcagaggc
    10261 tgaggtcggg ggcggtcgtg atgtcccgcg cggaaccggt gggctccagg acgcggtcga
    10321 tctccggggc cacggcgtcc gcgatccggc cggccggttc gccgagggcc gtgagcagcg
    10381 cggcgtgcgc gtacgcgagg cccgcgtacc ccttgcacca gccgccgttg cccgttccgt
    10441 tcccccggtc gcgcagcccc gcgtcctgcc agcggtggcg gccgtacgcc tcggcgaacc
    10501 gctccagatg ggtgcgggcg ccgctgtccc cgtcgaggcc cgccgtgacc atcgcggaca
    10561 gggcggcgat ccggccgaac ctgccgtggg ccaggccgag ttcctcgccg tcccggtgtg
    10621 cggccgggtc tccgtccacc gtgacgaggc ggcgcagcag ccgctcggcc ccggccccgg
    10681 tcacctcggt cgcgccgtgc tcggtgtggg cggcgaggtg gacgaggtag ccgccgtagc
    10741 cgttgaggtg gtcgaagtcg gcggcggaga gccggtcgac gttgaacgcg ccctgggccg
    10801 ggcggaatcg gacgtgctcg tcgcccgcgc ggaagcgggc gtcgggcgag gtcagccgcc
    10861 ggatctccca gtcggtcacc aggtcggaga gcacgccggt gaacggcgac atcggcagcg
    10921 gcgttccgtc gagcacggcc ggccggccgt gcacggccga ggcgcagacc cgctccaggt
    10981 ccacgccgat cggtgagact ccggtgcggg ccgcgctctg cgcgaggtgc agcagcagcc
    11041 caccgccgtc gtacagcgtg gcgtcgacgc cgccgaggcg cagcccgtcg ccccggaggc
    11101 ggggcgtcag ccaggtcggg gcgtccgccc cgccgacgac gaggtcgcgg agcagggcgt
    11161 gccagccggc cgggtcggcg aggtggacgg gcgaggcggc cggggcgggc ccgctgacgg
    11221 gctcccgccg ctcccacacg tcgtcggcgg aaccggccag ggcgtaccgg aggtagagcg
    11281 gatcacggtc ggcgggccgg gtgaagaacg accgtacggc ggcgagcgcg gactcgcggg
    11341 gggtgagctg tgcggcgctg cggatctcct cgtcgaagtc gccgcgcagc agcccggagt
    11401 cgcagtccac ggtgaagaac ggcacatcga ggtcgagcag ggccgcgacc tcctcccggt
    11461 ggaccgcgtc ggccgactcg gcggcggtgc cccggtaatg gcgcggcagc ttgccgagca
    11521 gctcggcccg gtcctgccgg ctgcccaggt gcacggggtg cgtggaggct tccaggaacc
    11581 gggcgtagat gtaggtcggg cggacgacct ggcgcacggc ccagccggcg gagtcccgta
    11641 cggccgcctc gacggcgtcg cggtgggcgg cgagcagcgt gcgggcctcg cggaatccgg
    11701 cgacgagctc gtccgtccag cggcgcgggt ccagcggatc gcccgccacg gtggccatgt
    11761 tggcgccgtg ctcgacgacg acctggctgc ggtcgaagcg gatgtcgtcg gtgcccgcgt
    11821 ccacgaccag gtacgactgg aggtgctcgg acgcccccgg ccgcacgcag ccgatcccgg
    11881 agatgtcgac gtccagcttg gccccggcgt aacgggccgg gaagagcagg gtgttgagca
    11941 ccgagcgctc gatgtcgagg ttgagcgagg cggcggccgg cgccgaacgg gcctggcccg
    12001 gcgcgatgtt gggcagcgac accagggtct cggtgtcgat gacgaccgga ccgtccgggg
    12061 tggcgatgat gttctcgtgg tgcaggtcgg tggcgcccag catcgacagg agcgcggcgg
    12121 accggccgaa gcggcggaag tagcgggcgc tgtgctccgg cgtcccgtcg aggtcggcgt
    12181 ggaccacgaa ctcctgccag acgtgggcgg gccggacgag cgtccggggg tgcagcgggc
    12241 cgaagaacga gccgtccgcg tcgaggagtg tgcgcaggga ggtcaggagc tgctggcagt
    12301 tgtcctgctg cggcttgtac acggcccgag agccgtcgtc ccggaccacc aggcagacgg
    12361 tccgcccgcc ccggtgggcg tcgccgagcc ccggggtgac ggagacgatc cggccgggcc
    12421 cgccgaggag cgcgtccagc tccgcgcggt ccgcgacggc ggcgtgcagc acatcggcca
    12481 ccgtccgcgc ggtgcgggcg gtggcgaggc gcagcagccg gtccagctcg gggaagcggt
    12541 cgagcaccgc ctcgcggccg ggggcctggg cgaggcgggc gtggaacgcc tcgtacccgg
    12601 tgtcctgggc gcggaaggag gcgatgaggg tgcggacgcc ggtctccacg cagaggccca
    12661 tgagcgagcg gagcgcggac tcggcgacac cggcgaggtc ggcgaggccg gcgagtcctg
    12721 cctggtcgtc ggtggtgtcc gggctctgga gggcggcggc gagcccggcg atgcgctgcg
    12781 cgccgtcccg cagatacggc gcgtagaacg cgccgaagac gtctgacctc tcgtcggtga
    12841 tgcgctgcac caggtcgtcg aggaacgcgt cgctcagttg cactcgtgga ctctcttgcc
    12901 gtcgtcgaag gtgggagggt ggggacgggc gccccggaag taccagttcc ggggcgcccg
    12961 caccccaccg gctcagcggg ttcagcagcg cttggtgcag ccgctcgtcg ggcagccgcc
    13021 ctgcatcgcg gcgctggcgc cgacgatcac ggtggtgacg gcggtggccg ggatgatggt
    13081 gggcgtgaag cccgcggcca gcgactccgg cgcgtccgcg agctcgacga gctcgtcggc
    13141 gctgacgtat ccggtggcgt cgttcatggc gatgtcgccc atgacggttc ctctctgttc
    13201 ttcctgcgtg gatgggtgtg gtgccagggc ccggcaggat gcgggcccgg ttcgtgggtg
    13261 cgccgtcgcg cccggccgtg gcctaggcga agcgcagcag ggaggggtgg ctccccgggt
    13321 ccaggtggcg gaggacggac caggcgagtc cggcctcccc gaccatgagg ctgttggtgt
    13381 acgcgtactt ggtgtccgag cgctgtccgt accgctccac gacctcgtcg aagagccgcg
    13441 gatacaggtc gtcgaggccg ccgccgtcgc cggtccgggc ggcctcgccg aacaggccgg
    13501 ggaccaggtc ctgtccgagc cgtacgatct ccgcgcaggc caggtcgccg tggcagtacg
    13561 tcgggttgtt gccgaagccg cggtccaggg tcagcccggc cagccggtcc agcaccgggc
    13621 ggggcaccgc gccgggcgcg tgctcgttgc tcatcagcgc gcccagcagc atcccgggag
    13681 ccccgtggca ccagccgtac gagcgctccg gctcgcccca gacgcgcggc cagtcgcggt
    13741 cgccgtcctc ctgcgcgtcg aggaccgcgc cgaggatccg cagcccgagg ccgtgcaccc
    13801 ccgggtcgcc gaactcggcc ccgtagcgca gcagtacggg cgcgatgccc atcgccccgt
    13861 gcgcgtaacc ggtgtacggg gtgacccgcg ggtccgccag gccgatgccg ccgagcgcct
    13921 cggtctcccg ggctgcgatc gtgcggaccg cctcggcgac gaccgcccgc tccgccgggt
    13981 cggtggcccg ctcgtgcagc gcgaggccga ccgccagcgc gcccgccatg ccgctgagga
    14041 agtcggtgcc ggcctcggcc cccgagcacc gggccagctc ccgcgccagc tcgccgagcc
    14101 ggccggcgtc cggctcgtcc agcagcccgc gcgccacgac gagggcgtac gcggtgccgg
    14161 ccatcccggt catcccgcct accgacaccc cctgctcggc gagctgcccg ccgcgcagct
    14221 gctcctcgac gaggtccagg acactgcgcg ccgccgccgc gaagtccgcc cggcccgtct
    14281 cacgggccag cgcggcgagg acgagggcgg ggcccgggct gccgccgtac aggtcgtagc
    14341 cgagggtgcc cgggctccac tggctctgcg agtcggtggt gacctgcggg gcgatccagg
    14401 tcgccgggtg gtgcggctcg gtgctcgcca cccgggtcgc gagcagccgc tccccgatcc
    14461 gtacggcctc gtcgacgaac cggccccggt ccacggcgac ggcgggcttc cccgccgggc
    14521 gcacggggac gaatccggtc tcctcctggt cggtgggcag cttgttgacg aacgagaagt
    14581 cgatcaggcg cagttcgcgc tcgatgacgc tctcgtccag cccgtggatc cgctcgcgca
    14641 cggtggtcag cggcggctcc gccagggcgt cggcccgtac ggcgccgtcc gtcgagccca
    14701 gcgcgcgcga cctggcggtg tacgagaagt acggcacgtc gccccgggcc atctgccgga
    14761 cctcggcgtc ggcgatggcg ggggagtcgc cggtgcgcag gacgacccgg ttcaggacgg
    14821 cggcgcggac gaccgggtcc gccatggcgt gcgggtgggt cgccatgcgc agcaactgcg
    14881 tgtagaagat ggtcgcctgg ttgacgtggc ggaactgcac atcgccgagg aactcctcga
    14941 cggcgtcgac gaccgcgtcc ggatggtccg ccgcgtaccg cagcacccgg ccgaactccc
    15001 tcttgacgat gtcccgttgg tcgttgacgg gcagctgggt ggcgcgctgc acggcgaggt
    15061 tggcgttggc ggccgtggtc gtcgtggtca ccattccgac gaacatgtcg tcgcggcccg
    15121 ggttctggag gctcagcgac ttgtacgggg agcgctggcc ggtgtcgtag ccgatcgcgc
    15181 cgatgtccat gccgtggtcg tcgtcgcccg agcgcacgac gagcggcagc agccccgacc
    15241 cgatgatcga ctcccggagc gtgagcgccc cggccttcga ggccgcgccg tcgtcgtacg
    15301 cctcggggag gttcagccgg ggcgacagca gggtctcggt gtcgatgacc acgggcccgg
    15361 cggcgcagga caccatgttc tcgaagtgga tgtcggtggc ccgcagcagg aagaggatgc
    15421 ccgcgagggt gccgatccgg gcgaagtagt ccttctgctc gcccgcgtac tcctcggtgg
    15481 ggatgaactc cacgaacccg ccgtgctcgg tcgggaccac ggcgacggtc ggcagatcgg
    15541 tgccgagccg gccgttcatc caggacacga aggagctgta gccggcctcc gcgccgatgg
    15601 ggtgcggctt gtagagcacc cggcggccgt cggtgaacag gacctgcgcg acggaccgcc
    15661 cgccgttgtg ggtgtcgccc tcgccgagga cgagacggtc gacccggggg tgttccggac
    15721 cgcccgccag gagggatccc aactgcggtg cggcagagcc gatttcctcg atgatctcga
    15781 cgacgtaccg ggcggaggcc tcgacctggc ggcccacgag gaagaagagg tgcggatagc
    15841 gcgcggtcaa ctcggcgtgc ccggcggggc tgttggtcca ccggcggaag gcggcgtacc
    15901 gctcctcggg cgtctcgccg tcgagcaggc ccgccgtgcg ccgccggtgc agctcctcga
    15961 ccagggtccg gatcatcagc cgggagacga gcccggtctg gtgcgtgacg aagtcgtcga
    16021 cgatccgctg gggcgcggcg atcgtgggcg actgcgcggc ggcatggcgt acgcggccgc
    16081 tccagggtgc gacgaagtgc cggaagtagt cgtggaagag cccgtcgggg tcgagggacg
    16141 gatcgtaggc ggggggcggg tcgggcagtt cctggtcctg ctcgccctcg tcctcggtcg
    16201 ccgctgcccg cagccgttcc tcgacgtgcg cgatcagctc ggggtcggtg agctccggca
    16261 gatacgtccg cagcgcttcg gcgatgccgg gggagacgtc gtgactgttc atgaacaccg
    16321 gatccaggac ggggcgggga gggaggggcc ctcggaggga ctgcccctca ggaggagagg
    16381 gggaggtgac gccgggaggt gggtcccggc gtcatacggt cacttgcagt tgttctggca
    16441 ctcggcggtg gccgtgcaga agttcccgtt gttccccagg acgtagctgg cgccgtagca
    16501 gctcagggag gacacgatgg ttccccagcc ctgaccggcg gcgctgacgg cgtcgaggtt
    16561 ctggtcgtcg atctcttcga ggatgccgac gttggggttc gccatgaggc tcacaccttt
    16621 cacgcgtgga agcggcgcgc ggctgtgggg ccgggccgtt ccgaatggat cttgacccct
    16681 tgaacgctag ggatcggatc cgtctcgcac ccccgcccgg ggacgggttc cgcccccgcc
    16741 ctggggggtg ttgttccccg cccggaacct cgccgggagt tcgggtgccg cgtggctcag
    16801 gcggggccgg tggaggcgcg ggtctccagg gaccaggcgt ggcggcggac ggtgtcgggg
    16861 gcggcccggt ccgcgaggat gtcgcagagc agctcggcgc aggcgcggcc gtacgcggcg
    16921 gggcgcaggt caacggcggt gaccggcggt tcggcgttgc gcgtggcggg cccgtcgacg
    16981 caggccgcga cgagcaggcc gctcccgctc ttcccgctgc cgccggcctt ctcgctgtcg
    17041 ccgacctccc ggccgagggc ggccgccgcg cgcaggacgc ccggggctga cccgtcgggg
    17101 gcgcagatca cggcgtcgac ggccgggtcg gcggtgagca gcgcccgggt ggtctcctcg
    17161 gcctccgccg gggtcgccgc gaacggcacg gtgcgcagcg ccatctccac cccgtgggcc
    17221 agcccccagg accgggccgt cgcgcgcagg gcggtcgccc aggcggagga gccggacggg
    17281 gcgagaacgg cggggcggcg ggcgccgcgc tcggcgacat ggtcgaggag ggcggtcagc
    17341 gaggcggcgt tgtcgcagac cacggcgccg ctgggggcgg cggccgggcc gaggtagcgc
    17401 tcgccggtca ccaccgggac gcccgcgtcg agcagccccg gcaccgcgct gtcgcccgcc
    17461 tcggggtcga tcaccagcag cccgtcgacg cgcgaggcga tccgcccgcc cgacgccccc
    17521 gagggcgcga gcagcaccag gtcgagcccg tcctcctggg cgcgctccac cgccccgaag
    17581 gcgaggttca tgtagtagtc cagccgggtc gcggtggccg gcagatgcag cccgacggcc
    17641 ccggtgctgg cgcggcgcag ccgccgggcg gcgctgttgg ggcggtagcc cagctcctcc
    17701 gccaccgcgc ggacccggtc ccgggtggcc ccggcgaccc gccccgagcc ctggagcgcg
    17761 tccgacacgg tgctcttgga gaccccggcg gcacgggcta cgtcgagcag ggtcacggtg
    17821 cgggaggtca cgggggtgaa gtctagacgt cggcggccgt acggcccgga gggttgccgg
    17881 aacgttccgg cacggttaga ttcgatccat tgccggaacg ttccggcacc cgctttcagc
    17941 ctccccgtcc cccgcccccg ctcctggaac cggtcatgcg tctgatcacc gcgtacaacc
    18001 cgcccgcctc cccgacccgg acccgccccg ccgagcgcgc ccccctgcgc gtcgcggcgg
    18061 tccagcagcg ctggcaccgc gacccggccg agcaccgcgc cgccctgctg gagggcatcc
    18121 ggctcgccgc cgccgagggg gcccgggtgg tctgcctcca ggagctgacg ctctcgccgt
    18181 acttcgcggt cgtccgccgc gccgaccacc ccgcgcccgc cgccccggag gagctgctga
    18241 ccggccccac cttcaccttc gccgccgagg ccgcccgcga gcacggggtg tacgtccacg
    18301 cctcgctgta cgagaaggcc ccggcggccg gcggcgagga cgacggcctc ggctacaaca
    18361 ccgcgatcct cgtcgccccc gacggcaccc tcgcccagcg cacccgcaag acccacatcc
    18421 cggtgaccga gggctattac gaggacgact ggttccgggc cggtccggcg ggcgacgacg
    18481 ccttcccgct ggtcacggtc gacgaagccc gcttcggcct gccgacctgc tgggaccagt
    18541 ggttcccgga gctggcccgc gcctactcgc tcgccggggc cgacgtcctc gtctacccga
    18601 ccgccatcgg ctccgagccc ggcttccccg gcttcgactc ccagccgctc tggcagaagg
    18661 tgatcaccgg caacgccatc gccaacgcca ccttcatgat cgtgccgaac cgcatcggcg
    18721 ccgagaacgg cctcaccttc tacggcagct ccttcatcgt ggacccgtac ggccgtgtcc
    18781 tcgcccaggc cccccgcgac gagcccgccg tcctggtcgc cgacctcgac ctggacgccc
    18841 ggcgcgactg gctggagctg ttcccgttcc tgaccacccg ccgccccgac gcgtacggcc
    18901 cgctcaccga gccccgctga gggggcccgg tggcggagcc gggggcgatc cagggcttgg
    18961 atctgctgct cccgcccgcg ccccggtgcg ccgatacgca cctgaaacag agccgcgcgg
    19021 tgctcgaagc gcgcccctga ccggccggaa gcggcgttcc cggaggctgt cggcgtaccc
    19081 gatccccggt gtgcacgacc gtcaggagac ctgtgccgtg ctgagcccac ccgaggccac
    19141 agcgcccgcc gccgacacgg cgcccgcgcc cggacccgtt cccgcgacgc ccgttcccgc
    19201 gacgccggac cccaccgcac ctgatcccac cgggcccgcc cccgccgggc ccgccgcccg
    19261 tcaccgcgcc gcccgcctgc tcgccgtcgg ggcggtcgtc tgggcggcgg tgacggcgct
    19321 ccacgcatcg atcccgaaca cgggcgtcaa cgcggggagc ctcttccaga cgctgctgcc
    19381 ctggacgggc ctcggcgtgc cgttcctgct cgtgctcgcc gccgtgctcc ggtcccggct
    19441 cgtcgccgtc gcggttctcg cgcccgccgt cgtgtgggtc acgctcttcg gcggcgccct
    19501 caccgacaag cgttccggcg gcggcgatct gacggtggtc agccacaacg tggacgaggc
    19561 gaacaccgat ccggccggca ccgcgcgcgt gctcgccggg gcgggcgcgg acgtgctggc
    19621 gctcgaagag ctgtccgacg cctcggcgcc cgtctactcc cgcgagctgg cgtccgccta
    19681 cccgcaccac gcggtgctcg gcggggtcgg catctggagc aggcacccgc tggcggacgt
    19741 gaaggaggtg ccgatcatgc cgtggacccg cgcgatgcgc gccacggtgc gggccccgga
    19801 cgggccgccc gtcgccgtgt acgcggtcca tctggcgtcg gtacgggtct cggcggcggg
    19861 cttcacgacg ggccgccgca acgaggcggc ccgggagctg gcggccgcgc tccgggcgga
    19921 gtccgcgcac cgcgtcgtgg tgctgggcga cctcaacggg acgtaccggg accgcgcgct
    19981 ggccccggtg acctcgcagc tgcggtccgc gcagggcgag gcgggcgcgg gcctcgggtt
    20041 cacctggccc gccgcgttcc cgatggcccg catcgacgac gtactggtac gggggctgac
    20101 cccgcgcgcg gcctggaccc tgcccgccac cggcagcgac cacctccccg tagcggccac
    20161 gctgacccgg tgacccggtg acccggtgac ccggtgaccc ggtgacccgg tgacccggtg
    20221 acccggtgac ccggtgaccc ggtgacccgg tgagccgatg accgggccct ccgccctccc
    20281 ccgactacga tgcgagcgac cgaccgatga cctcgaacgc ccaggtaggc agcgtgtccg
    20341 aagcccgggg cccggccccc gtcagcgtgc tcgtggtcga ggacgacgcc accatccgcc
    20401 gcgccgtcca gctggccctg gagcgctacg gctaccgggt cgcggtcgcc gccgacgggc
    20461 tcagcggcct ggaggcgttc cgcgcgggcg ggcacgacct gctgatcctc gacgtgatgc
    20521 tgcccgagct cgacggcatc ggcctctgcc accggatccg cgaggagagc cccgtacccg
    20581 tcctgatgat gtccgcgcgc ggcgacgccc tcgacgtggt cgcgggcctg gaggcggggg
    20641 ccgacgacta tgtgatcaag cccgtcgaca ccgccgtcat ggtcgcccgg atccgcgccc
    20701 tgctgcgccg cgccaccttc cgcccggacc cggtgggacg cgcgccgaag aagtccgacc
    20761 gggcccccga ccacgtcctg accttcggcg acctgaccgt cgacaccctc ggcatggagg
    20821 tgcgccgggc gggcgagccg gtgtcgctga cgccgaccga gctccggctg ctgctggagt
    20881 tcgccgccgc gcccggctcg gtgctcgacc ggcggcggct gctgcgcgag gtgtgggact
    20941 acggctggga gggcgacacc cgggtcgtgg acctgtgcgt gctgcggctg cgcaagaaga
    21001 tcggcagcgg gcggatcgag accgtccgcg gcttcggcta caagctcgtc cgcggctgag
    21061 cggccggcga ccgccgtgga cttcctcaac ccccgtgccc tgcgctggaa gatcgccgcc
    21121 ctggtcgccg ccgcatgctg cgcggtcgcc gccgtgatcg gcttcctggt gcacgacgcg
    21181 acccgcgaac gcggtctgcg cgtcggcacc gaccgcaccc tgacccggct gatcgccgcc
    21241 gagcgggagt tcgaccgtac ggggaaggcc ccggccgaca tcgacgtacg gaccagggcg
    21301 gagctgccgg agccgctggc gcgcgacctc gccgacgtca ccggcgacga actgccgggc
    21361 accggccgcg gatacgccac ctggtacgac gccgatccgc cgaactggca ctggatgtgg
    21421 ggcgcggtgg cggtcggcga cgaccggatc ctcgtcgtgc gggacgacat gagcaccgag
    21481 gtccgcagcc tccagctcct ggaccgctcc atcgtgaagt ccgttctcgc cgccctcctg
    21541 ttcgtcgtcc cgctcgccgc cctcgccacc gaaccgatca accggcggct gcgacacggg
    21601 gcccgtaccg cccgccggat cgcggacggc gacctggacg cccggatcgg tcccgccggg
    21661 cgggcccgtg acgagatcac cgagatgtcg gcggccgtcg acgacatggc caccgccctc
    21721 cagcgcaaac tggagaacga gcggcgcttc accgccgacg tcgcgcacga actccgcacc
    21781 ccgctcatgg gcctggtcac cgccgccggg ctgctgcccg agtccgacga ggcggcaagc
    21841 ctggtacggg accggctgcg ggccctgaac gcgctggtcg aggacctgct ggagatctcg
    21901 cgcctggacg cgggcgccga gcgggcccgc ctcgacccgg tgccgctggg cgagctggtc
    21961 gccgatgtgg tgcggcgtac gggcacggag acccgggtct ccgtggtgga cgcggaggtg
    22021 gtggagaccg acccgcgccg ggtggagcgg atcgtggtca acctcgtcgc caacgcccac
    22081 cggcacggcg cggcccccgt cgaggtgacc gtcaccggcg cgcggatcgc cgtacgcgac
    22141 cacggccccg gcttcccgcc ggacctgctg gagcggggcc cgcagcgctt ccgcaccggc
    22201 gcgagcgaac gcggccgggg gcacggtctc ggcctgacgg tcgcccaggg ccaggcggag
    22261 gtgctcggcg cccggctggc cttcgccgac gccccgggcg gcggagcgct cgcgacgctc
    22321 gacctggctc cgcacgcacg ccccgcctga atcccgcact ccggctgaca cggaacctga
    22381 tacggaaccg aaacgcactc tcgcgggggc ggaaacgccg ctgtacgggc ccggaagaac
    22441 gactcctcga aggtgactcc ggtacgggaa accgcaccgg tccacctgga ggaacccatg
    22501 caacccttgc ccgcagaccc cactgtcacc ccttccgccg gtcggggtgc gcgcttccgc
    22561 cgctcggtcc tcctgccgct gaccgccgcc gtgctcctcg cggccggcac gggagggtgg
    22621 tacgcgttcg gcggtggcgg gccggtgacc ggggccggcg gcgccgatgg gccgggggag
    22681 ggggtggcgc cgctcgcccg gtcgatgcag ctgccctggc cgcgcgaggg ccaggcgagc
    22741 gtggcggtcg aggggatcgg cagcctcggc acccggggcg agcagaagcc ggtgccgatc
    22801 gccagcgtca ccaaggtcat gacggcctac gtgatcctca aggaccgtcc gatgcgcgcc
    22861 gacgcccccg gcgcgaccgt ggtcgccgat cagcgggcgg ccgacgagtc gtactcctcc
    22921 gtcgagacga ccgcaccggt gctcgccggg cggacgtaca gccaacggcg gctgctggaa
    22981 ctgatgatgg tgccgtccgg caacaacgtg gcccggctgc tggcccgttg ggacgcgggc
    23041 gacgagaagg cgttcgtcgc gaagatgaac cggaccgccg ccgcactcgg catgcgcgcc
    23101 accacgtaca ccggggtgag cggcatggag gcgagtacga ggagcacggc ggcggaccaa
    23161 ctgcggctgg cccgggccgc catgaaggac ccggccttcc ggcagatcgt ggcgaccggc
    23221 tccgtcacgg ccccgggcgc cggggtgacc ttccgcaaca ccaacaagtt gctcgggcac
    23281 gacggcgtca tcggcctgaa gaccggctcc tccaccccgg cgggcggcaa cctcgtctgg
    23341 gccacgaggc aggaggtcgc cggagtgtcc cgtctggtca tcggcgtcgt gctgcaccag
    23401 cgcgccggca ccaccccggc cgagggcagc gccgccgccc acgaggccag ccgcgccctg
    23461 atcaccgcga tccgcgcgga cctcctggat gcggcgaaca gggcgtagcg gtgcgggacg
    23521 tgccggtcgt cgtcagtgca gggtcttcag catctccgcg gagaacgggg tgatgtccgc
    23581 cgtacgcccg ccgagggtct tcgccgccca ctcggggtcg gagatcagcg cccgcccgac
    23641 ggcgaccatg tcgaactcgt cgcgctccat ccggtcgagc agctgctcga tgccggtgac
    23701 cttggagtcg ttgccctgga aggcgctgaa gaagtcgccg tccaggccga ccgagccgac
    23761 cgtgagggtc ggccggccgc tgatcttctt cacccagccg gccaggttca ggtcggatcc
    23821 ctcgaactcc ggcagccagt agcggcgggt ggacgcgtgg aagacgtcga cgccggcctc
    23881 ggccaacggc gtgagcaggg cgtccagttc ctccggggtc cgagcgagct tcgcctcgta
    23941 gttgtccgac ttccactggg acatccggaa gaagaggggg aaggcgtcgg agacggcggc
    24001 gcggcaggcg gccacgatct cggcggcgaa acgggtccgg gcgaccaggt cgccaccgta
    24061 ggcgtcggta cgccggttgc tgccggacca caggaactgg tcgatcaagt agccgtgcgc
    24121 gccgtgcagt tcggcgccgt cgaagccgag gcgctcggcg gcggcggccg cgtcggcgaa
    24181 ggcggcgatg acgtcgtcga gatccttctg cgtcatggcg cggcccttgg gctcaccgct
    24241 cagcgacagt cccgaggggc cgaccggctc ggcgtccggg acgggcccgg cgccttcggt
    24301 gcgggtgacg cccacgtgcc agagctgcgg aatgatcgcg ccgcccgccc ggtgcacgga
    24361 gtccgcgaca tgcccccagc ccgcgagtgc ggcctcgccg tggaagcgcg gaacccggtc
    24421 gctggtcccg gcggactcgt ggtcgacgta ggtgccctcg gtgatgatca gcccgacgtc
    24481 accggcggcg cgccgggtgt agtagtccgc cacgtcctgc cccggaacgc cgtccgggga
    24541 gaactgccgg gtcatgggcg ccatcgcgat ccggttccga gaggtgagtc cgcggaccgt
    24601 gaacgggcgg gagagcgtgg ccgccgcacg ggcggcggcg ctgctcgcct ccgccgcgtc
    24661 ccgcacacct gccggggccg ccggtgctgc cggggccgtc acgtctgtca cgtctgtcac
    24721 gtcgggttcc tgtccattgc gggggtggtc cacccggccc caacgcactc gtgccgcgcg
    24781 gccatcccgg caacggcttc gatccgggta aagagtgggc aaagaacgga gtcggcctcc
    24841 ggtgcccttc gcgggcggct catccccgcc ccgacgcgga ccgctccggc ttctccggct
    24901 tcgccggcag cttcaggtcc gtgcaggccc cgcgccgcac ctgatccgcg gcgaacgcgg
    24961 agacgtacgc gcgcagcagc acactccgct cgtacgtctc ggcctcggtc ggcggcacgt
    25021 acgtcgagcc cggcttccgg cgccggtcgg gatagccctg accccagcgc gcggcgaagc
    25081 cgacgtcgtc cccgtcgcac ctggcgacgg cccacgcccg gtgctcggtg agggcgggcc
    25141 tccggccggc gccccggccc atcggcagcg ggtcggggtc cgagcccatc tcgtggacca
    25201 gcgggcccca gtcgccgagc caggaggtca gctcgacgat cgacgtaccc tctcgcgcgt
    25261 ccgggtacgt ctccgtggcg cgcagggtgc accggccgac gatcccgccg tcggcgatgg
    25321 cgatgcgcac gtcgccgttg cgtcccgcct ccgggacgcg ggtggtggcg agggcgtcgc
    25381 aggcggtgcc cttcgcccgg gcgcggggca cgtacgtccc ctcgtccggc accgcgccgt
    25441 ccgccggggc gggcagcggc tcgccgccgc agccgagctt ctcggtcacc gcgttcgtca
    25501 tgtggacggc gatccgcagc atggccgcct tctccgcagg gctgtgggcg gagtacgtcc
    25561 tggtgctcac gagcagccgc cggcgcaccg gggccgcctt ctcctgctcg cccgcttccg
    25621 ccctcgcttc cttcttctcc gccgccgaca ggacgccacg cgggcattcc ggcatcagat
    25681 ggacgatgcc ggggtcctcc tcgaagccgg gcagaccgcc cggcagcacg gcgtccggcg
    25741 ggcgggacgt tcccgcggaa ccgagcacct tgtcacggtc gcgacccgcc gggtaggtgt
    25801 cgaccgtgac cacggcgccg ccgttctcgt tcctcagcac acagctgtac gtgccgtcct
    25861 cggcgtcgaa ggactcctcc gcctctccga gccgcaggtc cgtccgcacg atctccaggt
    25921 caccggacgg cagttggccg ccgcacgcct cgcgcgccag ccaccagtcc ttcgccggtc
    25981 cgcgcatcgc gttcccggcg atcagcagga cgaccaccgt cccgaccgcg accagcagcc
    26041 aggtgcggtg ccgggaagcc cagtccttca gccggtcctc cagctgggtt cccgtccgat
    26101 tcgccggcct cggctccact cccgaccccc cgctcgcccg tacgccacgt ccgtaccagt
    26161 gtgagcaacg gccccgatgc cccgccctcc ggggtcactg ctctccgggg gcaccgccct
    26221 ccgggccgct ccgaggtgcc ggggccttcc ggcgagaccg agttgtgacc tgatcggcgg
    26281 ccggaggccg atgacttcgc ccgccggcac cg
//
