LOCUS       NZ_CP079114            31481 bp    DNA     linear   CON 06-SEP-2024
DEFINITION  Streptomyces sp. WY228 chromosome.
ACCESSION   NZ_CP079114
VERSION     NZ_CP079114.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. WY228
  ORGANISM  Streptomyces sp. WY228
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8286721)
  AUTHORS   Qin,S.
  TITLE     Volatile organic compounds produced by endophyte Streptomyces sp.
            WY228 mediate plant growth and salt stress tolerance by activating
            hormonal signaling and anthocyanin biosynthesis,
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 8286721)
  AUTHORS   Qin,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUL-2021) Key lab of biotechnology of medicinal
            plants, Jiangsu Normal University, No. 101 Shanghai Road, Xuzhou
            221116, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Canu v. 1.5
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 100.0x
            Sequencing Technology             :: Oxford Nanopore
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_019287315.1-RS_2024_09_06
            Annotation Date                   :: 09/06/2024 06:02:41
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,303
            CDSs (total)                      :: 7,213
            Genes (coding)                    :: 7,059
            CDSs (with protein)               :: 7,059
            Genes (RNA)                       :: 90
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 155
            CDSs (without protein)            :: 154
            Pseudo Genes (ambiguous residues) :: 0 of 155
            Pseudo Genes (frameshifted)       :: 83 of 155
            Pseudo Genes (incomplete)         :: 99 of 155
            Pseudo Genes (internal stop)      :: 10 of 155
            Pseudo Genes (multiple problems)  :: 36 of 155
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 03:35:29
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2689799
            Orig. end                         :: 2721280
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP079114.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..31481
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /candidate_cluster_numbers="3"
                     /contig_edge="False"
                     /product="lanthipeptide-class-ii"
                     /product="lanthipeptide-class-iii"
                     /region_number="11"
                     /rules="cds(LANC_like and DUF4135)"
                     /rules="(micKC and not PKS_KS)"
                     /tool="antismash"
     cand_cluster    1..31481
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /detection_rules="(micKC and not PKS_KS)"
                     /kind="neighbouring"
                     /product="lanthipeptide-class-ii"
                     /product="lanthipeptide-class-iii"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     cand_cluster    1..23423
                     /candidate_cluster_number="2"
                     /contig_edge="False"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..23423
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:13423](+)"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..13423
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     gene            complement(243..1676)
                     /locus_tag="KV381_RS11615"
                     /old_locus_tag="KV381_11615"
     CDS             complement(243..1676)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018384873.1"
                     /locus_tag="KV381_RS11615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_11615"
                     /product="glycoside hydrolase family 76 protein"
                     /protein_id="WP_218787204.1"
                     /transl_table=11
                     /translation="MLGALPAVANPASAAVPAPGAAAEVCNKHCDARDPASATADRVPV
                     HASVHGRSIALHLSDNDVMGWASIDDGAAGDETWLDRSFDGGRTWASGSKLGATAVPSG
                     RTGWRSQMYNVDDWNTGGIGALRACGKAGDRSEIACTGWARVNWNAGSRSTAAATALMM
                     NYDRNSGKFAGWWTSATALTSLIDNIRISHMPSYTYAISNTYEKLIGAEGGDFTNSYLD
                     DTGWWGLAWVAAYDLTGERRYLDTARKDADHMAAYWTGTCGGGVQWATDKPYKNAITNE
                     LYIQLSAALHNRIAGDTTYLRRAEDGWNWFKSSGMIYSGNTINDGLSENSDGTCSNNGD
                     TTWTYNQGVILAALAELNRATGDASLLDSARTLADASTTSSYLNPGGTLHEPYEPDSDC
                     TTDGDSFKGAYARGLGVLNKALPDRPYSAYLDRQADTAHEKNRNSLDQYGAHWAGPLTR
                     TGNGCQHSALDLMNAAQDS"
     misc_feature    complement(1658..1672)
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: weak, score: 22.1"
                     /tool="antismash"
     misc_feature    1659..1673
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: weak, score: 22.98"
                     /tool="antismash"
     CDS             complement(1879..2016)
                     /gene="allorf_2691678_2691815"
                     /locus_tag="allorf_2691678_2691815"
                     /protein_id="allorf_2691678_2691815"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MRCTLVKFEQLAPVSRGRGSAVLCGLGPWAQSRSQIVVGRAVLTC
                     "
     CDS_motif       complement(1942..2016)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MRCTLVKFEQLAPVSRGRGSAVLCG"
                     /locus_tag="allorf_2691678_2691815_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(1879..1941)
                     /prepeptide="core"
                     /locus_tag="allorf_2691678_2691815_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-7.10"
                     /molecular_weight="2087.4"
                     /monoisotopic_mass="2086.2"
                     /core_sequence="LGPWAQSRSQIVVGRAVLTC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MRCTLVKFEQLAPVSRGRGSAVLCG"
                     /leader_location="[1941:2016](-)"
                     /alternative_weights="2105.5"
                     /alternative_weights="2123.5"
     misc_feature    complement(1987..2003)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 15.07"
                     /tool="antismash"
     misc_feature    1990..2006
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 18.09"
                     /tool="antismash"
     gene            2015..2722
                     /locus_tag="KV381_RS11620"
                     /old_locus_tag="KV381_11620"
     CDS             2015..2722
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018511335.1"
                     /locus_tag="KV381_RS11620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_11620"
                     /product="VOC family protein"
                     /protein_id="WP_218785166.1"
                     /transl_table=11
                     /translation="MTETTIPLLPCRTSLIETAVDFYTALGFETTYLQKSPYAYAVVER
                     GAVELQLYGMKDYDPASSHSGCYVLTDDVDGLHTAFRAGLKAAYGRVPTRGLPRIGPLK
                     DMSYGVRQFLMTDPTGNTIRIGQAISDDPSHRPAPKETFARALHMADLFADSKQDLPGA
                     AKIIDRVLGLTDEQPTPVQRLRLLVLRGDIAQRMGDVERAAALLEEAAAVRLDADQQTL
                     AGDALARLAELRG"
     misc_feature    complement(2941..2956)
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: strong,
                     score: 19.52"
                     /tool="antismash"
     gene            3155..3514
                     /locus_tag="KV381_RS11625"
                     /old_locus_tag="KV381_11625"
     CDS             3155..3514
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004954136.1"
                     /locus_tag="KV381_RS11625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_11625"
                     /product="RNHCP domain-containing protein"
                     /protein_id="WP_098025683.1"
                     /transl_table=11
                     /translation="MSASSSMSSLDTFTCVRCGLTVAAYAPDGSRRNHCPSCLHSQHLV
                     DHVEGGRSDCEGRMAPISIAVLRTGDWMVVHRCTRCDELTSNPVCGDDNQLILMRMAVR
                     PLAQPPFPLEAFGDL"
     gene            3537..3956
                     /locus_tag="KV381_RS11630"
                     /old_locus_tag="KV381_11630"
     CDS             3537..3956
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010056536.1"
                     /locus_tag="KV381_RS11630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_11630"
                     /product="RNHCP domain-containing protein"
                     /protein_id="WP_030085521.1"
                     /transl_table=11
                     /translation="MTRRKPRRGSGRRPQRAKDVLHGPAGARGDAFRCVGCRLDVPLAA
                     PGTAHRNHCPSCLVSLHVDGRVPGDRAAGCRGRMVALSLSVRQDGEWMLIHHCLTCGRL
                     SANRIAGDDNALALVRLALRPLADAEIPVRAMLAL"
     gene            complement(4028..4582)
                     /locus_tag="KV381_RS11635"
                     /old_locus_tag="KV381_11635"
     CDS             complement(4028..4582)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010056538.1"
                     /locus_tag="KV381_RS11635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_11635"
                     /product="DinB family protein"
                     /protein_id="WP_086778435.1"
                     /transl_table=11
                     /translation="MTQSDAAEAWPEPPLAGTEAAAVLGALERQRATLAWKTSGLDAAG
                     LRATVGASTITLGGLLKHLAHVEDSHFARLWLDTPVGAPWNTVDWDSDPDWAYRTAAQD
                     TPEQLRMLWRESAARSRAVVDQALSTGGGLDQLGAYVTRNGERPNLRRILLDLIEEYAR
                     HVGHADLIRESVDGLTGEDPG"
     misc_feature    4748..4763
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 17.1"
                     /tool="antismash"
     misc_feature    complement(4748..4765)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 15.22"
                     /tool="antismash"
     gene            complement(4785..5636)
                     /locus_tag="KV381_RS11640"
                     /old_locus_tag="KV381_11640"
     CDS             complement(4785..5636)
                     /GO_function="GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018511319.1"
                     /locus_tag="KV381_RS11640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_11640"
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="WP_218785168.1"
                     /transl_table=11
                     /translation="MTNDDGGGGDLSRLSINQETLKQWSLPELVEGCVKAGIDKVGLWR
                     APVQEYGVERTARLLADAGLTVTSLCRGGFFTALDPAERARALDDNRAAIDEAAGLSTD
                     TLVLVSGGLPPGSRDLHGARERVGEALAELAPYAAARDVRLAIEPLHPMYAADRCVVST
                     LAQALDLAERFPAEQVGVVVDTYHLWWDDQAPAQIARAGAGGRIHSFQLADWITPLPAG
                     VLLGRGQLGDGSVDFRAFRRWVEDAGFDGPIEVEIFNEALWARDGAEALAEVADRYVRH
                     AC"
     gene            complement(5633..6787)
                     /locus_tag="KV381_RS11645"
                     /old_locus_tag="KV381_11645"
     CDS             complement(5633..6787)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010056542.1"
                     /locus_tag="KV381_RS11645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_11645"
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="WP_218785169.1"
                     /transl_table=11
                     /translation="MTTIHLPQGPYTPRTTPLDLAPGATAPASRTVFSAAHVVADPYAD
                     IAPGDPAAVDWESTLAFRRHLWAHGLGVAEAMDTAQRGMGLDWAGAAELIRRSAAEAKA
                     VGGRIACGVGTDQLPDDGTAPTLAEVRSAYEEQLALAEEHGAQPILMASRALARAASGP
                     EDYLATYAHLLRQASEPVILHWLGPMFDPALEGYWGSSDLDAATDTFLKVIAEHPDKVD
                     GIKISLLDAAREIDVRRRLPGGVRCYTGDDFNYPELIAGDERGFSHALLGIFDPLGPLA
                     AHAVRVLDTGDVDGFRALLDPTVELSRHLFQRPTRFYKTGVVFLAWLAGHQDHFTMVGG
                     LQSARSLPHLAKAYELADRLGLFPDPELAEHRMRALLAVHGGAR"
     gene            complement(6828..7979)
                     /locus_tag="KV381_RS11650"
                     /old_locus_tag="KV381_11650"
     CDS             complement(6828..7979)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016651 - oxidoreductase activity, acting
                     on NAD(P)H [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GFO_IDH_MocA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GFO_IDH_MocA_C3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1079: oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005317389.1"
                     /locus_tag="KV381_RS11650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_11650"
                     /product="Gfo/Idh/MocA family protein"
                     /protein_id="WP_030085508.1"
                     /sec_met_domain="GFO_IDH_MocA (E-value: 9.4e-09, bitscore:
                     34.7, seeds: 39, tool: rule-based-clusters)"
                     /sec_met_domain="GFO_IDH_MocA_C3 (E-value: 5e-26, bitscore:
                     89.8, seeds: 4226, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTRRTVRIAMNGVTGRMGYRQHLVRSILAIREQGGLDLGNGEVLW
                     PEPVLVGRRAHALEELAGRHGLTEWSTDLDAVLADDTVEIYFDAQVTSARVEAIKKAIA
                     AGKHVYTEKPTATDVEGALDLARLARDAGIKHGVVQDKIFLPGLRKLKRLIDGGFFGEI
                     LSVRGEFGYWVFEGDWQEAQRPSWNYRAEDGGGIVVDMFPHWEYVLHELFGQVTSVTAQ
                     VHTHVPRRWDEQGKPYEATADDAAYGIFQLAGGAVAQINSSWTVRVNRDELVEFQVDGT
                     HGSAVAGLRNCRVQHRSATPKPVWNPDLPVTESFRDQWQEIPDNQEFDNGFKAQWELFL
                     RHVALDTPYTWDLLAGARGVQLAELGLKSSAEGRRFDIPELTL"
     misc_feature    complement(7991..8011)
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 18.75"
                     /tool="antismash"
     misc_feature    8003..8014
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 15.83"
                     /tool="antismash"
     gene            8089..9225
                     /locus_tag="KV381_RS11655"
                     /old_locus_tag="KV381_11655"
     CDS             8089..9225
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1078: LacI family
                     transcription regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012380887.1"
                     /locus_tag="KV381_RS11655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_11655"
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="WP_086778433.1"
                     /transl_table=11
                     /translation="MTVTLADVAARARVSPATVSRVLNGNYPVAASTRERVLRAVDDLD
                     YVLNGPASSLAAATSDLVGILVNDIADPFFGIMAGAAQTQIGGPGDGSGRAGGEKLAVI
                     CNTGGSPERELTYLTLLQRQRAAAVVLTGGAVENPAHQAAMAAKLAKLADAGTRIVFCG
                     RPPLPEGDALVAALAFDNRGGGRRLTEHLISLGHRRIGYVAGPPERTTTRHRLEGHREA
                     LRAAGLDAAPDGGAEAGSDSGAETGGGAAGSGDQDRLTVHGPYDRRSGYEATLELLRRA
                     PDVTAIVAANDTVALGACAAVRDQGMRIPQDISVAGFDDLPFSVDAVPALTTVRLPLFE
                     AGARAGRLAMGKENPPPGGIATIAAELMIRGSTAAPRG"
     cand_cluster    8818..31481
                     /candidate_cluster_number="3"
                     /contig_edge="False"
                     /detection_rules="(micKC and not PKS_KS)"
                     /kind="single"
                     /product="lanthipeptide-class-iii"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    8818..31481
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[18817:21481](-)"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      complement(18818..21481)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="2"
     gene            9318..9833
                     /locus_tag="KV381_RS11660"
                     /old_locus_tag="KV381_11660"
     CDS             9318..9833
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="KV381_RS11660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="KV381_11660"
                     /product="hypothetical protein"
                     /protein_id="WP_218785170.1"
                     /transl_table=11
                     /translation="MTSDDVIAPEAIRAAWDSYRVLEKRTPDGERQEARRRVQAAVDAY
                     GRAEVSRGTVFLVGVLTGFLIAEQSGGEDRLDPLSDLIPAVIRRLPAFESADPAQLPMA
                     TGVLMAAAMGMDTVEWRDRFGPIPPEEALVHGFVLWLLADLFDSLAGQPGGIDRTMQNT
                     FDSMAAGQ"
     gene            10001..13423
                     /locus_tag="KV381_RS11665"
                     /old_locus_tag="KV381_11665"
     CDS             10001..13423
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007450767.1"
                     /locus_tag="KV381_RS11665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_11665"
                     /product="type 2 lanthipeptide synthetase LanM family
                     protein"
                     /protein_id="WP_256995047.1"
                     /sec_met_domain="DUF4135 (E-value: 1.4e-103, bitscore:
                     345.6, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 1.6e-26, bitscore:
                     91.7, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAEKDLIDRGTSRRLAPAAAAVAYGDDPAASAVSSPATALFEGAA
                     GEPWWLPGVVGGRPSGEPRWAVFAREAVASAPHDVVVADRAYPGLSGFGPVLAPFVEAA
                     AERLRGTLAEEAPAEEDGPAVGSPSADGPVADRPVVGGPVADGPVTDGPVAGGPVADGP
                     LPEGSSTVLGDFRRQLTRRLCRIAARTLVTELHEARRLGRLSGAGTEERFRDFVRLTAR
                     RDGLAELVTGYPVLARLLATACLNAGDAFAEMVVRLAADRHLLAPAGVLGHRAGAPDGA
                     LGGSAGPGVLTGVEAGAGDSHRGGRSVMLLRFADGTRLVYKPRPLAAHRHFNTLAEWFG
                     SLPGAPALRVLRVLDRGEYGWAEFVEERPCASVTETRRFYRRQGALLALLHALDGTDLH
                     HENLIACGPHPVLVDVETLFHPPLGPAGSTDPAARALHDSVHRVGLLPQLLVGDTSALD
                     MSAIGGGRAASSPIETADWADPGTDRMRLVRRAGRFTESANRPRLGGVAADPSAYTDAL
                     CDGFRAGYNAISEHRNELLGEGGLLWLFGADEVRVVPRPTWTYTTLLDESTHPDLMRDA
                     AERHQVLSLLRTPLLGVPALPGVEDEEIAELWSGDVPVFCTRPGGTELWSGTGRTVAGP
                     APGLSSHDTAPARPRPAAAPHDPALLSGLARVEAKVRAMDTVDRQDQERIIRAAMVSTS
                     PEPPHRAVPGGRAPSAATAPEPEQLLSAARSVGDQLVSLAYRHEGRTNWIGLELLGERY
                     WRLTPMAADLAGGYTGPALFLAQLAALTGAARYAEAAREALAPVPGLLDALHGRADELG
                     PLGSGAFAGLGGIAYALTEVGTLLGDREVLELAGPAVRLSCAASMAEDGYGVRGGVAGG
                     LVSLLAVYRATGRPEAWRGAERCAERIAAAPLPDSAGFADGAAGIGWALLRFAGAGGDV
                     RHRNAGLRALRLATALAEAGAAGRNVPGATGGALGGATAGAAGGTTALANPGALAGADG
                     EAAAPTEAAAAKPTAPAAGPAWCDGAAGIALAIADSHDALADPELAGWLAARSGELADI
                     GPLADDSLCHGESGLLELLGHRALPAARPAWVRRAGTMLAAADRAGPQCGTPGRVPHPG
                     LLTGLSGIGHGLLRAGFPDRIGSALLLRPSRAP"
     gene            13501..13698
                     /locus_tag="KV381_RS11670"
                     /old_locus_tag="KV381_11670"
     CDS             13501..13698
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010056547.1"
                     /locus_tag="KV381_RS11670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_11670"
                     /product="hypothetical protein"
                     /protein_id="WP_030085499.1"
                     /transl_table=11
                     /translation="MKQFRESALQASGDIAHEGSPEHPAGQISLGSTGGLGARSRLLSA
                     SEGESGYSHDLPWTTMTAPW"
     gene            13778..16711
                     /locus_tag="KV381_RS11675"
                     /old_locus_tag="KV381_11675"
     CDS             13778..16711
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1149: LuxR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015508338.1"
                     /locus_tag="KV381_RS11675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_11675"
                     /product="AAA family ATPase"
                     /protein_id="WP_218785172.1"
                     /transl_table=11
                     /translation="MRATSPVIVGRDEQIGLLSSALDAVQRRSGRALFFVGEAGIGKSR
                     LVGECAYRAYGAGMPVLRGRATSTGLVVPFRPLAEALASRFRAAGTPTDPELAPYHPAL
                     ARLVPEWRKGGSPGYPETVVELAEALLRLLSVLGREAGCAILLEDLHDCDTETVAVVEY
                     VIDNLADLPILFLGTLRPEPGAALDLVRSAERRHTATVRELGPLPDAQVRALTGACLEA
                     RPQEIPEAVHRRLAERAAGNPYLLEVLLADLLDTGRLRRTDDGWEAAEQPDAAVPSDIV
                     RSWARRLERLDEPVRDLLLASATLGSQFSVTVLQTVTGFEDRALFTHLRSAVEAGVIAP
                     DGAAPDRYTFRHSLTAEALISSLAPAERASLARRAAGAIEHSGEPLDEDGRQLVASLQL
                     AAGNRTGAARQFAEAGRRMLASGAHGSAVVLLERAHPLAAEGDRAAVAESLAVARAEGG
                     DLDGALALADALPPVPARSEAAARRGRTHVELAWAAVMAERTADAALQVEAARALLGAS
                     PPPGRRAALAVVDGYLSLLPGHEPGPGQKPPDPAEAEQAVREAAETAEAEGLPVVACQA
                     WQLLALLRREEGFDAADAALERMLSISTEHALPVWRVEALVRLGANAFMRTGDASRLLS
                     ARAAATELGALLLTRTVDGLLAMNAVLCARWEEAQEIVDRSAEASARVGDLSAHRYLLL
                     AGATMAAHRGRRREMDRALAAFRRAGGEQSLLVPLRSGLCRAFGALLEEDRERAVAGLD
                     EALAWELDHPSYYYLSGRYGLRPMLRVLAGEADRAELEEARAAPGGCLAWNRQFLELAD
                     AVLLGRAGDPAGAARLMASFGACSAPFPVAHHLGLRLVADAARADGWGEPVAWLRTAEE
                     YFYGAGVQPVASACRAALRQAGASVGQHRGGWDRIPSPLRTSGVTPREYEVFVLLPERP
                     GNQQIARRLSISPRTVEKHMASLLSKTGRADRAALCEFAAECAGEAV"
     misc_feature    14672..14674
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            16918..18831
                     /locus_tag="KV381_RS11680"
                     /old_locus_tag="KV381_11680"
     CDS             16918..18831
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1041:
                     transcriptional regulator, SARP family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003969054.1"
                     /locus_tag="KV381_RS11680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_11680"
                     /product="BTAD domain-containing putative transcriptional
                     regulator"
                     /protein_id="WP_256995048.1"
                     /transl_table=11
                     /translation="MTRPPARTGSAGAVYFSLLGPLTARLDGRELPLGPRKQRLVLATL
                     LARPNTPVPVDVLTDAVWPDDPPRTARKNLQVYVSAARALLGPAEDGGRDRVVHGCGGY
                     QLRIAEGELDTLRFGSLARAGRAEAGRGDLRSAARLLREALDLWEGPPLNDLRDSAGVA
                     EEADRLEARCLTVYEDWAEAEIELGRAAVAVDGLRDLVERHPLRERLRAAWMNSLHQSG
                     RQAEALAVYDDYRQLMARELGLEPSPAMAALYRSMLGRGREARRPAAARETVSAVALPA
                     CTGAFTGRREELRDLLDVLGGEERVVVVSGPAGAGKSALAVRAAHLLADRFPDGRVQVR
                     VRREDGTARGRTEILAELGRLCGVPEGNAAPEDAWQEWLARHRALVVLDGVPDEASVRG
                     LLPRSGACSVLVTARGQLAGLAPVHRIALPVLADSEALELLGKLIGIGRLRTDPAAALR
                     IVRACGALPLAVEVSGMRLAVLRHLPLAEYAARLEDPSAALDELVAGDVSVRHRVASGW
                     QDLADGDRWVLGRLAGLAEAGGFTLDRATTALGCEERTAIRAVESLIDAGAVTSPAGEV
                     TAHAALYEVPRLLGLYARERGASGRDGGAGAGGVTDQAGGVPDRAAAPARAAVAAGPLS
                     PG"
     gene            complement(18818..21481)
                     /gene="lanKC"
                     /locus_tag="KV381_RS11685"
                     /old_locus_tag="KV381_11685"
     CDS             complement(18818..21481)
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="lanKC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iii: micKC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018895798.1"
                     /locus_tag="KV381_RS11685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_11685"
                     /product="class III lanthionine synthetase LanKC"
                     /protein_id="WP_218785173.1"
                     /sec_met_domain="micKC (E-value: 1.8e-211, bitscore: 703.1,
                     seeds: 18, tool: rule-based-clusters)"
                     /sec_met_domain="Pkinase (E-value: 9e-08, bitscore: 30.5,
                     seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPGPQQTQLYCLADRTYYDTPARLPDEETRYPLDSAPPPEGWCRT
                     PGGLWTSMVPEHGEPAAQGWKIHVSTVPEEAEATLRDTTRVCLAHGVPFKFLRSEQALL
                     LMSGKYMSRSGAGKFLTLYPPDETVFLRLLDELTRVLAGRSGPYILSDLRIGDTPVHVR
                     YGAFTARWCRDANGERVPALRHPSGHLVPDERGVVFRVPPWVTVPGALRPHLAARAAAG
                     DAAFPYTVTKALQFSNAGGIYLARHRDTGRQVVLREARPHCGLDGAGDDAVTRLHREHR
                     ALTALAGLDCVPKVHGVTTVWEHHFLIEEHIEGNTLLEEIVARFALVRGAGTAAELAPY
                     TAWVDSITAQLTSAIAAVHARGLRFGDLHPNNIIVRPDGRVALIDFEYAVGLDDEDTPL
                     AGAPGLQAPVGTPGAEADGYALWATWLSMLMPLMELAGHDRAKALTLERWARRRYGLAS
                     DAGPRRPAVLRTVADDREREIAALLDGPAPDWAGLRTRLLAGIHAGATPERGDRLFPGD
                     PKSFATGGSDLAHGAAGVLYALHRVGAPVPDAWTDWLVDAARHRDPASPGGLFDGLPGT
                     AVVLARLGRPDEARELFARTAASAHPSACADLLTGRAGTALAALRLATAGTSAPGTGAV
                     DGAPDRAPAPDPELLETALRTAWDLDCLVRGEGGAGGGLTAPPSAGLLRGLSGVALLHL
                     ELHALTGEEWLLRAARTALYRDSGHCVAMPDGTVQVKDGRRHLLYLDQGSGGFALVAHA
                     YLARHEAPALAALLPGVHKGCTNEFVREPGLFTGRAGLVATARQLERGPAGPGVLASVR
                     NLSWHLIADGDRLLVPGAGLRRCSADLATGAAGLLLALHFLAGADSKDGTETGGTTHGA
                     PADDRPHDLLKLLTLG"
     gene            complement(21493..22764)
                     /locus_tag="KV381_RS11690"
                     /old_locus_tag="KV381_11690"
     CDS             complement(21493..22764)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1020: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006124642.1"
                     /locus_tag="KV381_RS11690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_11690"
                     /product="MFS transporter"
                     /protein_id="WP_030632136.1"
                     /transl_table=11
                     /translation="MATPLRSNRDFRLLWMSGLFAVLGSQMGALALPLLILRETGSAVQ
                     AGAVGTVSVCAVLITMLPGGVMADRVERRRLMRLCDVGSLAAVTALTLAVWNGHAPMAL
                     VLLVATAGAVLNSVYAPAAFGLMRAVVPPDQMGTATARLQARTSTVRLVGPLVGGALFG
                     VHQALPFVAQFVGLLISTVCVALVRTRSEARTKAGSVFSRRELTAGLAFLWQLPYLRTV
                     LLVFGLGMNFAFGALTFTALAVFSEGGRSGLGGGFVITCVSAGALVGALLAPRLAPDRH
                     VRTLIVITCWSCVLTAAALAWVSSPLLAGLLCALCMGLSTVASIGFLSTLLIVTPEDRL
                     GRVQSAASFLSSVVQPFGPLAGGALLTALGSSAAFGVTGCVLAVSAAVVTFAPSVRAGA
                     VPVPGRPAEEPRPAHDTAGRPGAL"
     CDS             complement(22846..23010)
                     /gene="allorf_2712645_2712809"
                     /locus_tag="allorf_2712645_2712809"
                     /protein_id="allorf_2712645_2712809"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MRRGGPRPTPRPRGARPADRRGQAVRGGSANTGAAPPRFVRPCPA
                     TSPMSSPMS"
     CDS_motif       complement(22927..23010)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MRRGGPRPTPRPRGARPADRRGQAVRGG"
                     /locus_tag="allorf_2712645_2712809_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(22846..22926)
                     /prepeptide="core"
                     /locus_tag="allorf_2712645_2712809_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-3.90"
                     /molecular_weight="2491.8"
                     /monoisotopic_mass="2490.2"
                     /core_sequence="SANTGAAPPRFVRPCPATSPMSSPMS"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MRRGGPRPTPRPRGARPADRRGQAVRGG"
                     /leader_location="[22926:23010](-)"
                     /alternative_weights="2509.9"
                     /alternative_weights="2527.9"
                     /alternative_weights="2545.9"
                     /alternative_weights="2563.9"
                     /alternative_weights="2581.9"
                     /alternative_weights="2600.0"
     gene            complement(23058..23216)
                     /locus_tag="KV381_RS11695"
                     /old_locus_tag="KV381_11695"
     CDS             complement(23058..23216)
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010070796.1"
                     /locus_tag="KV381_RS11695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_11695"
                     /product="hypothetical protein"
                     /protein_id="WP_165891054.1"
                     /transl_table=11
                     /translation="MSENTKPAGDETNETPEVEAHSVLDLQETSVQGGDTTDGNCISVL
                     SVVESQR"
     CDS_motif       complement(23115..23216)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MSENTKPAGDETNETPEVEAHSVLDLQETSVQGG"
                     /locus_tag="KV381_RS11695_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(23058..23114)
                     /prepeptide="core"
                     /locus_tag="KV381_RS11695_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-4.20"
                     /molecular_weight="1833.0"
                     /monoisotopic_mass="1831.9"
                     /core_sequence="DTTDGNCISVLSVVESQR"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MSENTKPAGDETNETPEVEAHSVLDLQETSVQGG"
                     /leader_location="[23114:23216](-)"
                     /alternative_weights="1851.0"
                     /alternative_weights="1869.0"
                     /alternative_weights="1887.0"
                     /alternative_weights="1905.0"
     gene            complement(23305..23466)
                     /locus_tag="KV381_RS11700"
                     /old_locus_tag="KV381_11700"
     CDS             complement(23305..23466)
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014046102.1"
                     /locus_tag="KV381_RS11700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_11700"
                     /product="hypothetical protein"
                     /protein_id="WP_170994579.1"
                     /transl_table=11
                     /translation="MSENTKPAADDANETPEVEAHSVLDLQETAVHGDRDIIAPPGNCI
                     SVLSVVEN"
     CDS_motif       complement(23347..23466)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MSENTKPAADDANETPEVEAHSVLDLQETAVHGDRDIIAP"
                     /locus_tag="KV381_RS11700_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(23305..23346)
                     /prepeptide="core"
                     /locus_tag="KV381_RS11700_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-7.30"
                     /molecular_weight="1294.5"
                     /monoisotopic_mass="1293.7"
                     /core_sequence="PGNCISVLSVVEN"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MSENTKPAADDANETPEVEAHSVLDLQETAVHGDRDIIAP"
                     /leader_location="[23346:23466](-)"
                     /alternative_weights="1312.5"
     gene            23799..24977
                     /locus_tag="KV381_RS11705"
                     /old_locus_tag="KV381_11705"
     CDS             23799..24977
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003969049.1"
                     /locus_tag="KV381_RS11705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_11705"
                     /product="radical SAM protein"
                     /protein_id="WP_218785174.1"
                     /transl_table=11
                     /translation="MELAELVARRPFPAAGLLIGLTRRCPLRCAHCSTGSDLFTRQEPD
                     GGQLERFVGSFTEENRPDVVMLTGGEPLLLPALAERLSTLARRAGSRTALLSGMFFARS
                     GSGRSGSARDGSTGRRRSGRYGGRRGAAIPPAILRAIRSVDHFSASLDVHHEREVPRAD
                     VFRALHRIRAEGVAVSLHLTGTGAADPYLAGLTRAVEEEFGGQVPCLVNEVRPFGRAAS
                     WARPARSGPDPAAASPCSMAAWPVVAFDGRVLACCNQDTVDRRPVPAHLDLGHIGADDW
                     ATVRRRALESPVLRMLRTVGPTHLAARYGSGPPAGSYCDGCRALGGDEAAMAGAQAVAG
                     GAAGALLDLTAAVRGSREGAQGVVRRHGCAAYAPLVVAGGPALPESEAEEVR"
     gene            24974..25738
                     /locus_tag="KV381_RS11710"
                     /old_locus_tag="KV381_11710"
     CDS             24974..25738
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015577230.1"
                     /locus_tag="KV381_RS11710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_11710"
                     /product="iron-containing redox enzyme family protein"
                     /protein_id="WP_218785175.1"
                     /transl_table=11
                     /translation="MSAPAPTSAGASLGRTGASARLRVKLLLLEPEFRDATHHMWRTEG
                     LLPRYRTYLCTMHAVIRASVPLMELALRRARQLDASGDLLAAPLAAYLEEHIREEAGHD
                     DWLLDDLRAAGGTPEDALGPLPSPLTASLVGSQYYWIEHHHPVALLGYIAVLEGYAPAP
                     GLTGRIARLTGLPAAALRTVREHSVLDTEHLDELYALLDRLPLGREREAAVAVSALHSL
                     DALTRLFVRLGRSAPAPSLRGAGPVPPMGVTP"
     gene            25735..25953
                     /locus_tag="KV381_RS11715"
                     /old_locus_tag="KV381_11715"
     CDS             25735..25953
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018959336.1"
                     /locus_tag="KV381_RS11715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_11715"
                     /product="aroma-sacti cluster domain-containing protein"
                     /protein_id="WP_030085485.1"
                     /transl_table=11
                     /translation="MTGPPENGERTVLPDALYEAGFPVDLLTEEQREVLSGLTPEELAL
                     LLDVKSRLDAVGPEVQAHGEIAGGALF"
     gene            26046..29399
                     /locus_tag="KV381_RS11720"
                     /old_locus_tag="KV381_11720"
     CDS             26046..29399
                     /GO_process="GO:0009190 - cyclic nucleotide biosynthetic
                     process [Evidence IEA]"
                     /GO_process="GO:0035556 - intracellular signal transduction
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014156177.1"
                     /locus_tag="KV381_RS11720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_11720"
                     /product="adenylate/guanylate cyclase domain-containing
                     protein"
                     /protein_id="WP_218785176.1"
                     /transl_table=11
                     /translation="MNCLACRQDLPPTARFCSSCGTPCATAAGATDTAGPPAAAATASA
                     VAPAGDERKPVTVLFCDLVGSTALSGVLDPETLRTVTLRYFEAMSAEIVARGGTPEKFI
                     GDAVMAVFGVPVVRDDDARRALAAALGMRRALARLNEELTATLGIELATRVGVNTGQVV
                     AGSDATARQALVSGETVNIAARLEQNAGRGEILIGPGTLLAAGPTVRAEPTGPLRLKGK
                     RDSVEAYRLLALGADDPELLRRFDVPFVGRDAERQALDAALERAVDGGGAGLLRVTGEA
                     GIGKTRLVREWLAGRSASGALVYGAGRCRSYGDHGTLAALADAVRSLVGPPAGQSAGPP
                     AGRSAGQSAVPAVGPAVDPAVDRAQGGADGPAVDGPAVDGLAVDDAMALLSGGLLRDGT
                     PNAPFEDMCAALTAVLERAARIRPVVLVLDDWHAAAPLLVRTVHRLTDGSGCAGVLVLC
                     AGRPDGPGEDSEPPAGAGHLQLTGLPREEAARLAAGLAGADGGTAPVDDRVLARAGGNP
                     LYLEQLLVGDREDPATASRPGGGPAPGEELPPTLQALLGARIGALARAERGVVDLAAVI
                     GREFTAPELVRLELSVQAGEGHGPGPLTGAAGPEHRRRVEEALAVLGRRRLVESGPPGG
                     REEAAYRFSSGLVHEVAYASLSKRAKADRHAWAAELPSVLRAGDGAVGGHLERAYRYRA
                     ELGLLDDAARRLRDRAAAALGRAGAQAAARSDLHWAHGLLERAVDLCPGDPAAARRLGE
                     VRVALGRTGEGAELLRRVRDSGADAVEAAHARLALAVLDPAAAPGPAAVARTVLPVFEA
                     AGDSTGRARAHLRLAQQFQRSGRHEEAERDQARALEHAVLAGAEPERAGALGAIGISLW
                     RGPVPVPAAVVRCRTLLAAHGAGRPTVRITLNCPLAVLYALQGRAEEARGCLAEAERLA
                     GKLGFAEAEVFLPVFRATVEALSGRSAAALELLGRADAAARRTGAAGMRTAVALDAARL
                     ELDEGREDLAAARLAGVGDTSGLSRADAVDLAGLRARLAARSAPEEAAGHADRAVRASL
                     LTDSPLVQATAELDRAHTLAALGRWPEAGASARSAGAHFTGKGHLPGVRRVSGFLAHPP
                     LAMATTRERS"
     gene            29403..30332
                     /locus_tag="KV381_RS11725"
                     /old_locus_tag="KV381_11725"
     CDS             29403..30332
                     /GO_function="GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S8"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1075: alkaline serine protease, subtilase family"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006124651.1"
                     /locus_tag="KV381_RS11725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_11725"
                     /product="S8 family serine peptidase"
                     /protein_id="WP_030085481.1"
                     /sec_met_domain="Peptidase_S8 (E-value: 6.8e-21, bitscore:
                     73.5, seeds: 43, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTTEPAPAQAQAESVRPRARTAPGQGLTWSLRGRGPDDVPVLAD
                     AGPPLGRPTGPATGRGVRVCVVDSGVERDHPLIGPLAGSWVVVKDGESGEIAVEPTTTG
                     DTCGHGTACAGIVRRTAPECEIHSVRVLGERFSGTGDVLMAGLRWAVEQRFDVVNLSLS
                     TTRTRFAQELHSLADSAYFARTVIVASAHNTPVESFPWRFASVISVGSHQEDDPELHLY
                     NPDPPVEFFGPGQNVTVPWLGGRTIRTTGNSFATPYVAGLCARVLSAHPRMTAFQLKNA
                     LYLSAANVRPAPRPSSTPAGDIRDDSEN"
     gene            30316..30933
                     /locus_tag="KV381_RS11730"
                     /old_locus_tag="KV381_11730"
     CDS             30316..30933
                     /GO_function="GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010062910.1"
                     /locus_tag="KV381_RS11730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_11730"
                     /product="GAF domain-containing protein"
                     /protein_id="WP_030085479.1"
                     /transl_table=11
                     /translation="MTPRTDSATSFSATATVADAPRSELLQSVVDVARAIFGAEASSVF
                     LLDEEADELVFQAVSGQGEEFLVGRRFPAGRGIAGWVATSGEPMVVDDLSADPSFDRSL
                     AESTAYVPNALMAAPLISDARILGVLEVLDPSPQARSGVRELDLLAMFARQAAAALRVL
                     TPERVREAEQRAVSAGGALEGARREDALKLLGSLERLLRGVG"
     misc_feature    31021..31035
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.8"
                     /tool="antismash"
     misc_feature    31229..31238
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.16"
                     /tool="antismash"
ORIGIN
        1 gaggggcggg ggcggcgcgg cgtgggccat ggtcgcggag gccaggacca gggtggccgc
       61 ggacaggatg acggtcaggc cgcggcgcag ggcgcgtccg cgcggggtcg gccgtactgc
      121 gggcatggga ctccttgagg agggaggagg cgggacgggc gggaggaaga gacggtggag
      181 gacacgcggt cacgcgtggt ctccaccggt ctcatgtcat ggcgtcgcgg gcgggcgtgg
      241 actcagctgt cctgcgccgc gttcatcagg tcgagcgcgc tgtgctggca gccgttgccc
      301 gtgcgggtga gcggacctgc ccagtgggcg ccgtactggt cgaggctgtt gcggttcttc
      361 tcgtgcgcgg tgtcggcctg ccggtcgaga taggcgctgt acgggcggtc ggggagcgcc
      421 ttgttgagga cgccgaggcc cctggcgtaa gcacccttga aggagtcacc gtccgtggtg
      481 cagtcggagt ccggctcgta cggctcgtgg agcgttccgc cggggttgag gtaggaggag
      541 gtcgtggagg cgtcggccag ggtgcgggcg ctgtccagga gcgacgcgtc gccggtggcg
      601 cggttgagtt cggcgagggc ggccaggatg acgccctggt tgtacgtcca ggtcgtgtcg
      661 ccgttgttgg agcaggtgcc gtcggagttc tcgctcaggc cgtcgttgat cgtgttaccg
      721 gagtagatca tgccgctgct cttgaaccag ttccacccgt cctcggcacg ccggaggtag
      781 gtggtgtccc cggcgatacg gttgtggagt gcggcgctga gctggatgta cagctcgttg
      841 gtgatcgcgt tcttgtaggg cttgtcggtc gcccactgca ccccgccgcc gcacgtgccg
      901 gtccagtagg cggccatgtg gtcggcgtcc ttgcgcgccg tgtccaggta acgccgctcg
      961 ccggtcaggt cgtacgcggc cacccaggcg aggccccacc aacccgtgtc gtccaggtag
     1021 gagttggtga agtcgccgcc ctcggcaccg atgagcttct cgtaggtgtt cgagatcgcg
     1081 tacgtgtaac tgggcatgtg gctgatccgg atgttgtcga tcagcgaggt gagcgcggtg
     1141 gcggaggtcc accagccggc gaacttcccc gagttccggt cgtagttcat catcagggcc
     1201 gtcgccgcgg ccgtactccg gcttccggcg ttccagttga cgcgggccca gccggtgcag
     1261 gcgatctccg accggtcgcc cgcctttccg caggcacgga gcgcgccgat gccgccggtg
     1321 ttccagtcgt ccacgttgta catctgcgag cgccagccgg tgcggccgga gggcacggcg
     1381 gtggcaccga gcttgctgcc ggaggcccag gtgcggccgc cgtcgaagga gcggtccagc
     1441 caggtctcgt cgcccgccgc tccgtcgtcg atggaggccc agcccatgac atcgttgtcg
     1501 gagagatgaa gggcgatgga acgcccatgg acggaggcat ggacggggac ccggtccgcg
     1561 gtggcgctcg ccggatcgcg ggcgtcgcag tgcttgttgc agacctctgc ggccgcaccg
     1621 ggcgccggga ccgccgcgga cgcggggttc gccacggccg ggagggctcc cagcatgagg
     1681 acggcggcca gggaggccag cagggccggc ccgagggatc tgagaggggt tctggggagc
     1741 atcgggcttc ctctgatgag tcccgcgggc gacgggcgga ggccgcccgt cgcccgcgga
     1801 aggggtgggg ggctcgccgc cagagaaccg gcgcgaccat ccgtccgtca aggtcgcacc
     1861 tgccgaccga gaaggagatc agcaggtcaa cacagctcgc cccaccacta tttgggaccg
     1921 agattgggcc cacgggccca gcccgcagag cacggccgac cccctccccc tcgacactgg
     1981 cgctaactgt tcaaatttga ctagagtgca tcgcatgacc gagacgacga tccctctgct
     2041 gccctgccgg acctcgctga tcgagaccgc cgtcgacttc tacaccgccc tgggcttcga
     2101 gacgacgtac ctgcagaaga gcccgtacgc gtacgccgtc gtcgagcggg gagcggtcga
     2161 actccagctg tacggcatga aggactacga cccggcgtcc tcccactccg ggtgctacgt
     2221 cctcaccgac gatgtggacg gcctgcatac ggcgttccgg gcggggctca aggcggccta
     2281 cgggcgcgtc ccgacgcggg ggctgccgcg catcggcccg ctgaaggaca tgtcgtacgg
     2341 ggtacggcag ttcctgatga ccgacccgac cggcaacacg atccggatcg gccaggcgat
     2401 cagcgacgac ccgagccacc ggcccgcccc gaaggagacg ttcgcccgcg ccctgcacat
     2461 ggcggacctc ttcgcggact ccaagcagga tctgccgggt gcggcgaaga tcatcgaccg
     2521 ggtgctgggg ctgacggacg agcagccgac cccggtacag cgcctgcggc tgctcgtcct
     2581 gcgcggggac atcgcccagc ggatgggcga tgtggaacgg gcggcagcgc tgctggagga
     2641 agcggcggcg gtccgactcg acgcggatca gcagaccctg gcgggcgatg cgctggccag
     2701 gctggcggag cttcggggct gagacgggga gagggaggga gggaaaggac aggagaggag
     2761 aggggggaag ggaggacgag ccgggcgtcg gctaattcgg tggccggtcc ctcggccccc
     2821 ttgttacggt gctcgctcct cgaccgcggg ctccgaccgc gggtgatctc tgggcgtgag
     2881 ccctggaaag cagttgatgt atgccccgga cagtgactcc gagcctccct cgtcgcgcct
     2941 gtgacgtcgg ggtgaccggg cctgaccgtc cgcggccgcc gtacgcggcc gactgctgac
     3001 acctcacggc cggctgccgt cccggagccg tccggccccg ctcccccgta cgtccctgac
     3061 gcgaggggtg ctcggtactt ccctgctgct tcgttcctca tcctcggcaa ggagtatccg
     3121 ggtgtctcac gacaaccccc agcaccgctc aggcatgtcc gcctcatcct cgatgtcctc
     3181 actggacacc ttcacctgcg tgcgctgcgg actgaccgtc gccgcgtacg cgcccgacgg
     3241 cagccggcgc aatcactgcc ccagctgcct gcactcgcag cacctcgtcg accacgtcga
     3301 gggcggccgc tccgactgcg agggccggat ggccccgatc tccatcgcgg tgctgcgcac
     3361 cggcgactgg atggtcgtcc accgctgcac ccggtgcgac gagctgacct cgaacccggt
     3421 ctgcggggac gacaatcagc tgatcctgat gcggatggcc gtacgtccgc tggcccagcc
     3481 gcccttcccg ctcgaagcct tcggtgacct gtgaaccggg cgaacgggag gctccgatga
     3541 cgcggcgcaa gccccggcgg ggatcaggac ggcgtccgca gcgggccaag gacgtgctgc
     3601 acggaccggc cggggcgcgc ggcgacgcgt tccggtgcgt cggctgccgg ctcgacgtcc
     3661 cgctggcggc gccgggcacc gcccaccgta atcactgccc gtcctgcctg gtcagcctgc
     3721 atgtggatgg ccgggttccg ggcgaccggg cggcggggtg ccgtgggcgg atggtggccc
     3781 tgagcctgtc ggtgcggcag gacggggagt ggatgctcat ccaccactgc ctcacctgcg
     3841 gacggctcag cgccaaccgc atcgcgggcg acgacaacgc gctggcgctc gtccggctgg
     3901 cgctgcgacc gctcgcggac gcggagatcc ccgtccgggc gatgctcgcg ctgtgatccc
     3961 gtgatcccgt gatcctgtgg ccgcccggtg accgccgggc ggccctcgga cacccccggc
     4021 cctcaggtca ccccgggtcc tcgcccgtca ggccgtcgac cgattcccgg atcaggtcgg
     4081 cgtggccgac atggcgggcg tactcctcga tgaggtccag gaggatacgg cggaggttcg
     4141 ggcgttcgcc gttgcgggtg acgtacgcgc cgagctggtc caggccgccg ccggtgctca
     4201 gcgcctggtc gacgacggcc cgggagcggg ccgccgactc ccgccacagc atgcgcagtt
     4261 gctcgggggt gtcctgggcg gcggtgcggt aggcccagtc ggggtcgctg tcccagtcga
     4321 ccgtgttcca gggcgcgccg accggggtgt cgagccagag gcgggcgaag tgactgtcct
     4381 cgacgtgtgc cagatgcttg agcaggccgc ccagggtgat ggtggacgca ccgaccgtgg
     4441 cccgcagccc ggccgcgtcc aggcccgagg tcttccaggc cagcgtggcc cgttggcgtt
     4501 ccagcgcgcc gaggacggct gccgcctccg taccggcgag gggaggttcg ggccaggctt
     4561 ccgctgcgtc gctctgcgtc atggcggcag atcctaacga acggcgggaa agcggaatgg
     4621 ggcccggcct cgcggccgga cccccctcgc tttcccctcc cgtcgggcct tcccgttccc
     4681 cccggacccc tccccggaag tcccgacgcc atgtgtgaca cgggagggta cgcaaaggtt
     4741 gcagcccttt acgatctctt tacttttggt ggtgtgcggg gctctcagca ggcatgtcgc
     4801 acatagcggt ccgccacttc cgccagcgct tccgcgccgt cgcgggccca cagcgcctcg
     4861 ttgaagatct ccacctcgat cggcccgtcg aacccggcgt cctccaccca gcggcggaac
     4921 gcgcggaagt ccacgcttcc gtcgcccagt tggccccggc ccagcagcac acccgccggg
     4981 agcggggtga tccagtcggc cagctggaag gagtggatgc ggccgcccgc acccgcgcgg
     5041 gcgatctgcg cgggcgcttg gtcgtcccac cagaggtggt aggtgtcgac gaccaccccg
     5101 acctgctcgg ccgggaagcg ttccgcgagg tccagggcct gggcgagggt ggagaccacg
     5161 cagcggtcgg cggcgtacat cgggtgcagc ggttcgatcg ccaggcgcac gtcgcgggcc
     5221 gccgcgtacg gggccagttc cgccagcgcc tcgcccaccc gctcgcgggc cccgtggagg
     5281 tcgcggctgc cgggcgggag gccgccggag accaggacca gggtgtcggt ggacaggccg
     5341 gccgcctcgt cgatcgccgc ccggttgtcg tccagggcgc gggcgcgttc ggccgggtcg
     5401 agggcggtga agaagccgcc ccggcagagg ctggtgaccg tgagcccggc gtcggcgagc
     5461 agccgtgccg tgcgctcgac gccgtactcc tgcaccgggg cccgccacag gcccaccttg
     5521 tcgatgcccg ccttgacgca gccctcgacc agctcgggca acgaccactg cttgagcgtt
     5581 tcctgattga tgctcaggcg ggacaggtcg ccgccgccgc cgtcgtcgtt cgtcatcgtg
     5641 cgcctccgtg gaccgccagc agggcccgca tacggtgttc ggccagctcc gggtccggga
     5701 acaggcccag cctgtccgcc agttcgtacg ccttcgccag atgcggcagc gagcgggccg
     5761 actggaggcc gcccaccatc gtgaagtggt cctggtggcc ggccagccag gccaggaaca
     5821 ccacgcccgt cttgtagaag cgggtgggcc gctggaagag gtggcgggag agttcgacgg
     5881 tggggtcgag gagggcccgg aagccgtcca cgtcacccgt gtccaggacc cgtaccgcgt
     5941 gcgccgccaa ggggcccagc gggtcgaaga tgcccaacag ggcgtggctg aagccgcgtt
     6001 cgtctcccgc gatcagttcc gggtagttga agtcgtcgcc cgtgtagcag cgcaccccac
     6061 ccgggaggcg gcggcggacg tcgatctcgc gggccgcgtc caggagggag atcttgatgc
     6121 cgtcgacctt gtccgggtgc tcggcgatca ccttcaggaa ggtgtccgtg gccgcgtcca
     6181 ggtcggagct gccccagtag ccctccaggg ccgggtcgaa catcgggccc agccagtgca
     6241 ggatcaccgg ttcggacgcc tggcgcagca ggtgggcgta ggtggcgagg tagtcctccg
     6301 gaccgctcgc cgcccgggcc agcgcgcggg aggccatgag gatcggctgg gcgccgtgct
     6361 cctcggccag ggccagttgc tcctcgtacg ccgacctgac ctcggccagg gtgggcgcgg
     6421 tgccgtcgtc ggggagctgg tcggtgccga cgccgcaggc gatccggccg cccaccgcct
     6481 tcgcctcggc ggccgagcgg cggatcagtt cggccgcgcc cgcccagtcc aggcccatcc
     6541 cgcgctgcgc ggtgtccatg gcctccgcga cacccaggcc gtgcgcccac aggtggcggc
     6601 ggaaggcgag cgtggactcc cagtcgacgg ccgccgggtc gccgggggcg atgtcggcgt
     6661 acgggtcggc gaccacatgg gcggccgaga agaccgtgcg ggaggcgggg gccgtcgcgc
     6721 ccggcgcgag gtcgagcggg gtggtgcgag gcgtgtaggg gccctgcggg aggtggatgg
     6781 tcgtcatggc agcgtcctcc gaccgcgcgg cgcaccggtc gcgcgggtca cagggtcagc
     6841 tccgggatgt cgaaacggcg gccctcggcg gacgacttca ggcccagctc ggcgagttgg
     6901 acgccccggg cgccggccag caggtcccag gtgtacgggg tgtccagggc cacgtggcgc
     6961 aggaacagct cccactgcgc cttgaagccg ttgtcgaact cctggttgtc cgggatctcc
     7021 tgccactggt cgcggaacga ctcggtgacc gggaggtccg ggttccagac cggcttcggg
     7081 gtcgccgagc ggtgctggac acggcagttg cgcaggccgg cgacggcgga gccgtgcgtg
     7141 ccgtcgacct ggaactccac cagctcgtcg cggttgaccc ggaccgtcca ggaggagttg
     7201 atctgcgcga ccgccccgcc cgccagctgg aagatgccgt acgcggcgtc gtcggcggtc
     7261 gcctcgtacg gcttgccctg ctcgtcccag cgccgcggaa catgcgtgtg cacctgggcc
     7321 gttacggagg tgacctggcc gaacagctcg tggagcacgt actcccagtg cgggaacatg
     7381 tcgacgacga tgccgccgcc gtcctccgcg cggtagttcc acgagggtcg ctgggcctcc
     7441 tgccagtccc cctcgaagac ccagtagccg aactccccgc gcacggacag gatctcgccg
     7501 aagaagccgc cgtcgatcag acgcttcagc ttgcgcaggc ccggcaggaa gatcttgtcc
     7561 tggacgacac cgtgcttgat gccggcgtcc cgcgcgagcc gggccaggtc gagggcgccc
     7621 tcgacgtccg tggccgtcgg cttctcggtg tagacgtgct tgcccgcggc gatggccttc
     7681 ttgatcgcct ccacccgggc cgaggtgacc tgggcgtcga agtagatctc gaccgtgtcg
     7741 tccgcgagca ccgcgtccag gtcggtcgac cactcggtca ggccgtgccg cccggcgagt
     7801 tcctccaggg cgtgggcgcg gcggccgacg agcacgggct cgggccacag gacctcgccg
     7861 ttgccgagat ccaggccgcc ctgttcgcgg atcgcgagga tcgagcgcac caggtgctgt
     7921 cggtatccca tgcgtcccgt gacgccgttc atggcgatgc gcactgtcct gcgtgtcacg
     7981 aaggtccctc catacagccg tagcaagcgc tttctatcgg agatgacgct agcctgccga
     8041 cagcggccgg acaagagggg gccgcacgtg acctcacgga ggacagcgat gacagtcacc
     8101 ctggcggatg tggcggcccg cgcccgggtg tccccggcca ccgtctcccg cgtgctgaac
     8161 ggcaactacc cggtggcggc ctcgacccgg gagcgggtcc tgcgcgcggt ggacgacctg
     8221 gactacgtgc tcaacgggcc cgccagttcg ctcgcggcgg ccacctcgga cctggtcggc
     8281 atcctggtca acgacatcgc cgacccgttc ttcgggatca tggcgggggc ggcccagacg
     8341 cagatcggcg ggccggggga cggttccgga cgggcgggcg gcgagaagct ggccgtcatc
     8401 tgcaacaccg gcggctcccc ggagcgcgaa ctcacctatc tcacgctcct ccagcgccag
     8461 cgcgccgccg ccgtcgtcct caccggcggc gcggtcgaga acccggcgca ccaggccgct
     8521 atggcggcga agctggcgaa gctcgcggac gcgggcaccc ggatcgtctt ctgcgggcgg
     8581 cccccgctgc cggagggcga cgcgctcgtc gccgcgctcg cgttcgacaa ccgcggcggc
     8641 ggacgccggc tcaccgagca cctgatctcg ctcggccacc gcaggatcgg ttacgtcgcc
     8701 gggcccccgg aacgcaccac cacccggcac cgcctggagg gccaccgcga ggcgctgcgc
     8761 gcggcggggc tggacgcggc tccggacggc ggggcggaag ccgggtccga cagcggtgcg
     8821 gaaaccgggg gcggggcggc cggctccggg gatcaggacc ggctcaccgt gcacgggccc
     8881 tacgaccggc gctcgggcta cgaggccacc ctcgaactcc tgcgcagggc accggacgtg
     8941 accgcgatcg tggccgccaa cgacaccgtg gcgctgggcg cgtgcgcggc cgtacgggac
     9001 cagggcatgc gcatccccca ggacatctcg gtcgcgggct tcgacgacct gccgttctcg
     9061 gtggacgcgg taccggccct cacgacggtc cggctgccgc tcttcgaggc gggcgcgcgg
     9121 gcgggacggc tcgcgatggg caaggagaac ccgccgccgg gcggtatcgc gacgatcgcg
     9181 gcggagctga tgatccgggg gtcgacggcc gcgcctcggg ggtgaggccc ggccgtcggc
     9241 tcccggagtg agccggtcgg tgtgcgacgg ctctccggcg gatctcgtct cgcctcgctt
     9301 cgtctacggt cggcttcatg accagtgacg acgtaatcgc gcctgaggcc atccgcgcgg
     9361 cgtgggactc ctaccgggtc ctggagaagc ggactccgga cggggaacgc caggaggcac
     9421 ggcggcgggt ccaggccgct gtggacgcct acgggcgtgc ggaggtgtcc cgggggaccg
     9481 tgttcctggt gggcgtgctg accgggttcc tgatcgccga acagtccggc ggcgaggacc
     9541 gccttgatcc gctcagcgat ctgatccccg ccgtgatccg caggctgccc gccttcgagt
     9601 cggccgaccc ggctcagctt ccgatggcca ccggcgtcct catggccgcc gcgatgggca
     9661 tggacaccgt ggagtggcgc gaccggttcg ggccgattcc gccggaggag gctctggtgc
     9721 acggcttcgt gctgtggctg ctcgccgacc tcttcgactc cctggccggg cagcccggcg
     9781 gcatcgatcg cacgatgcaa aacaccttcg actccatggc cgccggacag tgacccggcc
     9841 gccggccgat tcgccctgaa tcaccgtccg ttggcacgcc gtgcgggcca ggacgcgaaa
     9901 gatgggggcg actcccccat gcgcccgcgc cgctccccca gcacgatggt cccgggcggc
     9961 ccgaccggga ccgggcccag gagcggggag gtgcggagcg gtggcggaga aggatctgat
    10021 cgacagaggg acgagccgtc gcctcgcccc cgctgccgcc gctgtcgcgt acggcgatga
    10081 cccggccgcc tccgccgtct cctcccccgc caccgccctg ttcgagggtg cggccggaga
    10141 gccgtggtgg cttcccggtg tcgtcggcgg caggccctcc ggcgaacccc gctgggcggt
    10201 cttcgcccgg gaggccgtgg cgtcggcccc gcacgacgtg gtggtcgccg accgtgcgta
    10261 ccccgggctc agcggtttcg ggccggtcct cgcgccgttc gtcgaggcgg cggcggagcg
    10321 gctgcgcggc acgctcgccg aggaggcgcc cgcggaggag gacggtcctg cggtgggcag
    10381 tccctcggcg gatggtcccg tggcggatcg ccccgtggtg ggcggtcccg tggcggatgg
    10441 ccccgtgacg gatggccccg tggcgggcgg tcccgtggcg gacggtcctc tgccggaggg
    10501 ttcctcgacc gtactcggcg acttccggcg gcagttgacg cgtcggctct gccggatcgc
    10561 ggcgcgcacc ctcgtgacgg agctgcacga ggcgcggcgg ctgggccggt tgagcggggc
    10621 ggggaccgag gagcgcttcc gggacttcgt gcggctgacc gcccggcgtg acgggctcgc
    10681 cgaactcgtc accggctacc ccgtgctggc ccgcctcctc gccacggcct gcctgaacgc
    10741 gggcgacgcg ttcgcggaga tggtcgtacg gctcgccgcc gaccggcacc tgctcgcccc
    10801 tgccggggtg ctcggccacc gggccggcgc tccggacggg gcgctcggcg ggagcgcggg
    10861 acccggggtg ctcaccggcg tcgaggccgg ggcgggcgac agtcatcgcg gaggccggtc
    10921 ggtgatgctg ctgcggttcg ccgacggcac ccggctggtc tacaagccgc gcccgctcgc
    10981 ggcccaccgg cacttcaaca ccctggccga gtggttcggt tcgctgccgg gcgcccccgc
    11041 gctgcgggtg ctgcgggtgc tggaccgggg agagtacggc tgggccgagt tcgtcgagga
    11101 gcggccctgt gcctcggtga cggagacccg gcggttctac cggcggcagg gcgccctgct
    11161 ggccctgctg cacgcgctgg acggtacgga tctgcaccac gagaacctga tcgcctgcgg
    11221 cccgcacccg gtcctggtcg acgtggagac cctgttccac ccgccgctgg ggcccgccgg
    11281 ttccaccgac ccggccgccc gcgccctgca cgactcggtc caccgggtgg gcctgctccc
    11341 gcagttgctc gtcggggaca cgtccgcgct cgacatgtcc gccatcggcg gcggccgggc
    11401 cgcctcgtcg ccgatcgaga ccgccgactg ggcggatccc ggaaccgacc ggatgcggct
    11461 ggtgcggcgg gcgggccggt tcaccgagtc cgccaaccgg ccccggctgg gcggcgtggc
    11521 ggccgacccc tccgcgtaca ccgacgccct ctgcgacgga ttccgcgccg ggtacaacgc
    11581 gatcagcgag caccggaacg aactcctggg cgagggaggg ctgttgtggc tcttcggcgc
    11641 cgacgaggta cgggtcgtgc cgcgcccgac ctggacgtac acgacgctgc tggacgagtc
    11701 gacccacccc gatctgatgc gggacgccgc cgaacggcac caggtcctgt cgctgctgcg
    11761 caccccgctc ctgggcgtgc ccgcgctgcc cggggtggag gacgaggaga tcgcggagct
    11821 gtggtccggt gatgtgccgg tgttctgcac ccggccgggc ggcacggagc tgtggagcgg
    11881 caccggccgt acggtcgcgg ggccggcccc cggcctctcc tcgcacgaca ccgccccggc
    11941 ccgaccccgc cctgccgcgg ccccgcacga tcccgccctc ctcagcgggc tggcgcgcgt
    12001 cgaggcgaag gtgcgcgcga tggacaccgt ggaccggcag gaccaggaac ggatcatccg
    12061 ggccgccatg gtgagcacct cgcccgagcc gccgcaccgg gcggttccgg gcggccgggc
    12121 cccgagcgcg gcgaccgcgc cggagcccga gcaactgctg tccgccgcac ggtcggtggg
    12181 cgaccagctc gtctcgctcg cctaccggca cgagggccgc accaactgga tcggcctcga
    12241 actgctcggc gaacgctact ggcggctgac gccgatggcg gcggacctcg cgggcggcta
    12301 caccggcccc gcactcttcc tcgcccagct ggcggcgctc accggcgccg cccggtacgc
    12361 ggaggcggcc cgtgaggcgc tcgccccggt cccggggctg ctggacgcgc tgcacgggcg
    12421 ggccgacgag ctcggccccc tgggctccgg cgccttcgcg ggcctcggcg gcatcgcgta
    12481 cgcgctgacc gaggtgggca cgctgctggg cgaccgggag gtcctggagc tcgcgggtcc
    12541 ggccgtccgg ctgagctgcg cggcgagcat ggccgaggac gggtacgggg tgcgcggcgg
    12601 ggtggcgggc gggctggtct cgctgctcgc ggtgtaccgc gccaccggcc gcccggaggc
    12661 ctggcgtggt gccgagcgct gcgccgagcg gatcgccgcc gccccgctcc ccgactccgc
    12721 gggcttcgcc gacggggcgg cggggatcgg ctgggcgctg ctgcggttcg ccggggccgg
    12781 gggcgacgta cggcaccgga acgccgggct gcgggcgttg cgcctggcga cggccctcgc
    12841 ggaagccggg gcggcaggcc ggaacgttcc cggggccacc ggcggagccc ttggcggcgc
    12901 caccgccgga gcggccggcg gtaccaccgc cctggcgaac cccggagccc ttgccggagc
    12961 ggacggcgaa gccgccgccc cgacggaagc cgcggcggcg aaacccacgg ctccggccgc
    13021 cgggcccgcc tggtgcgacg gggcggccgg gatcgcgctg gcgatcgcgg acagccacga
    13081 cgcgctggcg gacccggagc tggccggctg gctggcggcg cgctccggcg aactggcgga
    13141 catcggtccg ctcgccgacg acagcctgtg ccacggcgag tcggggctgc tcgaactcct
    13201 cggccaccgg gcgctgcccg ccgcacggcc cgcgtgggta cgccgggccg ggacgatgct
    13261 ggccgccgcg gaccgggccg gaccgcagtg cgggacgccc ggccgggtgc cgcacccggg
    13321 gctgctcacc gggctctccg ggatcgggca cgggctgctc cgggccgggt tccccgaccg
    13381 gatcggctcc gccctgctcc tgcgcccctc ccgggcgccc tgacccaccc ccgaccaccg
    13441 ttcccgatga ccacgcaccg ttgctgatca ccgcaccgac caacaaagga tgaggcagag
    13501 atgaagcagt tccgcgaatc ggccctgcag gcgtccggcg acatcgcgca cgagggctcg
    13561 cccgaacacc cggccgggca gatctccttg ggctccaccg gaggcctcgg tgcgcgcagc
    13621 agactcctca gcgcctcgga gggcgagagc ggttacagcc acgacctccc ctggaccacc
    13681 atgacggccc cctggtgacc ggatccagcc aactcgacgc caattgagcc gaattggtcc
    13741 gctgccgtgg gagttgtcac tccagtaatg tgcggccatg cgagccactt cgccggtcat
    13801 cgtcgggcgg gacgagcaga tcggactgct gagcagcgcc ctggacgccg tacaacggcg
    13861 ttcggggcgc gcgctgttct tcgtcgggga agccggtatc ggaaagtccc ggctggtggg
    13921 cgaatgcgcc taccgggcct acggggcggg catgccggtg ctgcgcggcc gggccacctc
    13981 gaccgggctc gtcgtcccgt tccgcccgct cgcggaggcg ctggcctcgc ggttccgggc
    14041 ggcgggcacc ccgaccgatc cggagctcgc gccgtaccat ccggcgctgg cccggctggt
    14101 cccggaatgg cgcaagggcg ggtcgccggg ctatccggag acggtcgtcg agctggccga
    14161 ggcgctgctg cggctgctgt ccgtgctggg ccgggaggcg ggctgcgcga tcctgctgga
    14221 ggatctgcac gactgcgaca cggagaccgt cgcggtcgtc gagtacgtca tcgacaacct
    14281 cgccgatctg ccgatcctgt tcctgggcac cctgcgcccg gagccgggcg ccgcactgga
    14341 cctcgtacgc tccgccgagc gccgccacac cgccaccgtg cgggagctgg gcccgctgcc
    14401 cgacgcccag gtgcgggcgc tgaccggtgc ctgtctggag gcgcggcccc aggagatacc
    14461 cgaggcggtg caccggcggc tggccgaacg cgccgcgggc aacccgtacc tgctggaagt
    14521 gctgctggcg gacctgctgg acaccggccg gctccggcgg accgacgacg ggtgggaggc
    14581 ggcggaacag cccgacgccg cggtcccctc ggacatcgtc cgcagctggg cgcgcaggct
    14641 ggagcggctg gacgaaccgg tgcgggacct cttactggcg tcggcgaccc tgggcagcca
    14701 gttctcggtg accgtgctcc agaccgtcac cggtttcgag gaccgggccc tgttcaccca
    14761 tctgcggtcc gcggtggagg ccggtgtcat cgccccggac ggcgcggccc ccgaccgcta
    14821 caccttccgg cactcgctca ccgccgaggc cctgatctcc tcgctggccc cggccgaacg
    14881 cgcctcgctg gcccgccgcg ccgccggggc catcgagcac tccggggagc cgctggacga
    14941 ggacgggcgg cagctcgtgg cgtcgttgca gctggccgcg ggcaaccgga cgggggcggc
    15001 ccgccagttc gcggaggcgg gcagacggat gctcgcttcg ggggcgcacg gctcggccgt
    15061 ggtgctgctg gagcgggcgc acccgctggc cgccgagggc gaccgggccg ccgtcgccga
    15121 gtcgttggcg gtggcccggg ccgagggcgg cgatctggac ggcgcgctgg cgctggcgga
    15181 cgcgctgccg ccggttccgg cgcgttccga ggccgccgcc cggcgcggcc ggacccatgt
    15241 cgagctggcc tgggcggcgg tcatggcgga gcgcaccgcc gacgcggcgc tccaggtgga
    15301 ggcggcccgg gccctgctcg gcgcgtcgcc gccgcccggc cgccgggccg cgctcgcggt
    15361 ggtcgacggc tatctgtccc tgcttcccgg ccatgagccc ggccccgggc agaagccccc
    15421 ggacccggcg gaggccgagc aggccgtgcg ggaggcggcg gagaccgccg aggccgaagg
    15481 gctgcccgtg gtcgcctgcc aggcctggca gttgctggcg ctgctgcggc gcgaggaggg
    15541 cttcgacgcc gcggacgccg cactggagcg gatgctgtcg atctccaccg aacacgccct
    15601 gccggtctgg cgggtggagg cgctggtgcg gctcggcgcc aacgcgttca tgcgcaccgg
    15661 ggacgcctcc cggctgctct ccgcccgggc ggccgccacc gaactgggcg cgctgctcct
    15721 gacccgtacg gtcgacgggc tgctcgccat gaacgcggtg ctgtgcgccc gttgggagga
    15781 ggcgcaggag atcgtcgacc gctcggcgga ggccagcgcc cgggtcggcg atctgtcggc
    15841 ccaccgctat ctgctgctgg ccggggcgac gatggccgcg caccgggggc ggcggcggga
    15901 gatggaccgg gcgctggccg cgttccggcg ggccgggggc gagcagtcgc tgctggtgcc
    15961 gctccggtcg gggctgtgcc gggcgttcgg ggcgctgctg gaggaggacc gggagcgggc
    16021 ggtggccggt ctggacgagg cgctggcctg ggagttggac catccgagct actactacct
    16081 gagcgggcgg tacgggctgc gcccgatgct gcgggtcctg gcgggcgagg cggaccgggc
    16141 ggagctggag gaggcgcggg cggcgcccgg cggctgcctc gcctggaacc ggcagttcct
    16201 ggagctggcc gacgcggtgc tgctggggcg ggcgggtgac ccggccgggg cggcccggct
    16261 gatggcgtcc ttcggggcgt gttccgcgcc cttcccggtc gcccaccacc tggggctgcg
    16321 gctggtcgcg gacgcggccc gcgcggacgg gtggggcgag ccggtggcgt ggctgcggac
    16381 cgccgaggag tacttctacg gggccggggt gcagccggtc gcctccgcgt gccgggcggc
    16441 gctgcggcag gccggggcga gtgtgggcca gcaccggggc ggctgggacc ggatcccgtc
    16501 gccgctgcgg accagcgggg tgacgccgcg cgagtacgag gtattcgtgc tgctgccgga
    16561 gcggcccggg aaccagcaga tcgcccggcg gctgtccatc tcgccgcgca cggtggagaa
    16621 gcacatggcc agcctgctca gcaagacggg gcgcgcggac cgggcggcgc tgtgcgagtt
    16681 cgcggccgag tgcgccggcg aggcggtctg aggcctcgcg tcaggggcgg gcggaacctg
    16741 tgcacccggg ccatgggggc cgacgcgggc aacatggggg cgtcgggcgg tttcggtcgg
    16801 gtacgcgggc ggaaaatgcg ggcggggccc cgatgtgcgg gggccggacc ggcagcagga
    16861 tcggggcgtg cgtacggccc actccgccgc ccgtcccccg tttccggagg cccgctgatg
    16921 acccgacctc ccgcccgtac cggttccgca ggtgcggtgt acttctcgct gctcggcccg
    16981 ctcacggccc ggctggacgg ccgcgagctg ccgctcggcc cgcgaaaaca gcgcctggtc
    17041 ctcgccaccc tgctggcccg ccccaacacc cccgtaccgg tcgatgtgtt gaccgacgcg
    17101 gtgtggccgg acgacccgcc gcgcaccgcc cgcaagaacc tccaggtgta cgtcagtgcc
    17161 gcccgcgccc tgctcggtcc ggccgaggac gggggccggg accgggtggt gcacgggtgc
    17221 gggggctatc agctgcggat cgccgagggc gagctggaca ccctgcgctt cgggtcgctg
    17281 gcccgggcgg gccgggcgga ggccgggcgg ggcgatctgc ggtccgccgc ccggctgttg
    17341 cgggaggcgc tggacctctg ggaggggccg ccgctgaacg atctgcggga ctccgccggg
    17401 gtggccgagg aggcggaccg gctggaggcc cgctgtctga cggtctacga ggactgggcg
    17461 gaggccgaga tcgaactggg ccgggcggcc gtcgcggtgg acgggctgcg ggacctggtg
    17521 gagcgccatc cgctgcggga gcggctgcgg gccgcctgga tgaactcgct gcaccagtcc
    17581 ggccggcagg ccgaggcgct ggcggtgtac gacgactacc ggcagcttat ggcacgggag
    17641 ttgggcctgg agccgagtcc ggcgatggcg gcgctctacc gctcgatgct cggccggggg
    17701 cgcgaggccc ggcggcccgc cgccgcccgg gagacggtga gcgcggtggc gctgcccgcc
    17761 tgtaccgggg ccttcaccgg ccgccgcgag gaactgcgcg atctgctcga tgtgctgggc
    17821 ggcgaggagc gtgtggtggt cgtctcgggc ccggccggtg cggggaagtc ggcgctggcg
    17881 gtccgggcgg cccatctgct cgccgaccgg ttccccgacg gccgcgtcca ggtgcgggtg
    17941 cgccgggagg acggcacggc gcgcggccgg acggagatcc tggcggagct gggccggctg
    18001 tgcggggtgc cggaggggaa tgccgccccc gaggacgcct ggcaggagtg gctggcccgg
    18061 caccgggcgc tggtcgtgct ggacggcgta ccggacgagg cgtccgtacg ggggctgctg
    18121 ccccggtcgg gcgcgtgctc cgtactggtc accgcccggg ggcagttggc cggactcgcc
    18181 ccggtgcacc ggatcgcgct gcccgtgctg gcggacagcg aggccctgga actgctgggc
    18241 aagctgatcg ggatcgggcg gctgcggacc gacccggcgg cggcgttgcg gatcgtccgg
    18301 gcctgcgggg cgctgccgct cgcggtggag gtgagcggga tgcggctggc ggtgctgcgg
    18361 catctcccgc tggcggagta cgcggcccgg ctggaggatc cgtcggccgc gctggacgaa
    18421 ctggtcgccg gggacgtctc cgtacgccac cgggtcgcgt ccggctggca ggacctggcg
    18481 gacggcgacc ggtgggtgct gggccggctg gccgggctcg ccgaggccgg gggcttcacc
    18541 ctggaccggg ccacgacggc gctgggctgc gaggagcgga cggcgatccg ggccgtggag
    18601 tcgctgatcg acgccggtgc ggtgacctcg cccgccggag aggtcaccgc gcacgccgcg
    18661 ctgtacgaag tgccgcgcct gctcggcctg tacgcccgcg agcggggggc gtcgggacgg
    18721 gacggcgggg cgggcgccgg tggcgtaacc gatcaggccg gtggcgtacc ggaccgggcc
    18781 gccgcgcccg cccgtgcggc cgtggcggcc ggtccgctca gcccagggtg agcagcttca
    18841 gcaggtcgtg cgggcggtcg tcggcggggg ctccgtgggt ggtccccccg gtctccgtac
    18901 cgtccttact gtccgcaccg gccaggaagt gcagggccag cagcagcccg gccgccccgg
    18961 tggccaggtc ggcggagcag cgccgcagac ccgccccggg caccagcagc cggtcgccgt
    19021 cggcgatcag gtgccaggac aggttgcgta cggaggcgag cacccccggt ccggccgggc
    19081 cccgctccaa ctgacgggcg gtggcgacga gtccggcccg gccggtgaag agacccggct
    19141 cccggacgaa ctcgttggtg cagcccttgt gcaccccggg cagcagcgcg gcgagcgcgg
    19201 gcgcctcgtg ccgggccaga taggcgtggg cgaccagggc gaagccgccg ctgccctggt
    19261 cgaggtagag caggtggcgg cggccgtcct tgacctggac ggtgccgtcg ggcatcgcga
    19321 cgcagtggcc ggagtcccgg tacagggcgg tgcgggcggc gcgcagcagc cactcctcgc
    19381 cggtgagcgc gtggagttcg aggtgcagca aagcaacgcc gctcagtccg cgcagcagtc
    19441 cggcggaggg cggggcggtc aggccgccgc ccgccccgcc ctcgccccgg accaggcagt
    19501 ccagatccca ggcggtgcgc agggccgtct ccagcagctc cgggtccggg gccggggccc
    19561 gatccggagc accgtccacc gcgcccgtgc ccggggccga cgtgccggcc gtggccaggc
    19621 ggagcgcggc cagggccgtg cccgcgcggc cggtcagcag gtccgcgcag gcggaggggt
    19681 gcgcggaggc ggcggtccgg gcgaacagct cccgcgcctc gtccgggcgg ccgagccggg
    19741 ccaacaccac ggcggtgccc ggcaatccgt cgaacaggcc gccgggcgac gccgggtcgc
    19801 gatggcgggc ggcgtccacc agccagtccg tccaggcgtc cgggaccggg gcgccgacgc
    19861 ggtggagggc gtacaggaca ccggcggccc cgtgcgccag gtcgctgccg ccggtggcga
    19921 aggacttggg gtcgccgggg aagagccggt cgccgcgctc gggtgtcgcg cccgcgtgga
    19981 ttccggcgag cagccgggtg cgcaggcccg cccagtcggg ggcggggccg tcgaggaggg
    20041 ccgcgatctc gcgctcccgg tcgtccgcca cggtccgcag gacggcgggg cggcgcgggc
    20101 ccgcgtcgga cgccaggccg tacctccggc gggcccagcg ttccagggtc agggccttgg
    20161 cccggtcgtg cccggccagt tccatcaggg gcatcagcat gctgagccag gtcgcccaga
    20221 gcgcgtagcc gtcggcctcg gcgccggggg tgccgacggg cgcctggagg cccggcgcgc
    20281 ccgccagcgg ggtgtcctcg tcgtcgaggc ccacggcgta ctcgaagtcg atgagggcca
    20341 cacggccgtc ggggcggacg atgatgttgt tggggtgcag atcgccgaag cgcagccccc
    20401 gggcgtgaac agccgcgatc gcgctggtga gttgtgcggt gatcgagtcc acccaagcgg
    20461 tgtacggggc gagttcggcg gccgtgcccg ccccgcgcac gagggcgaag cgggcgacga
    20521 tctcctccag gagggtgttc ccctcgatgt gctcctcgat caggaagtgg tgttcccaca
    20581 cggtcgtcac gccgtgcacc ttcggtacgc agtccagtcc ggccagcgcg gtcagggccc
    20641 ggtgctcccg gtgcagccgg gtcaccgcgt cgtcgcccgc cccgtcgagc ccgcagtgcg
    20701 gccgggcctc gcggagcacc acctgccggc cggtgtcccg gtgccgggcg aggtagatac
    20761 caccggcgtt ggagaactgg agggccttgg tgacggtgta cgggaacgcg gcgtcgcctg
    20821 cggccgcccg ggcggccaga tgcgggcgca gcgccccggg cacggtgacc cacggcggca
    20881 cccggaacac cacgccgcgc tcgtcgggca ccaggtggcc cgacggatgg cgcagggcgg
    20941 gcacccgttc gccgttcgcg tcccggcacc agcgggcggt gaacgccccg taccgcacgt
    21001 gcaccggggt gtcgccgatc cggaggtcgc tgaggatgta cggaccgctg cggcccgcga
    21061 ggacccgggt cagctcgtcg agcaaccgca ggaagacggt ctcgtccggc gggtagagcg
    21121 tgaggaactt ccccgcgccg gagcgggaca tgtacttgcc ggacatcagc agcagcgcct
    21181 gctcgctgcg gaggaacttg aacggcaccc cgtgggcgag gcagacccgg gtggtgtcgc
    21241 gcagggtcgc ctccgcctcc tccgggaccg tggagacatg gatcttccag ccctgcgcgg
    21301 ccggttcgcc gtgctcgggc accatcgagg tccacaggcc gcccggggtc cggcaccagc
    21361 cctcgggggg cggggccgag tccagcgggt agcgggtctc ctcgtccggc agccgggccg
    21421 gggtgtcgta gtacgtacgg tcggcgaggc agtagagctg ggtctgctgc ggtccgggca
    21481 cggcgttcct cctcagagtg cgccgggacg accggcggtg tcgtgggcgg gtcggggctc
    21541 ttccgccggg cggccgggga ccggaaccgc cccggcgcgt acggaggggg cgaacgtcac
    21601 cacggccgcc gagacggcca gcacgcaccc ggtcaccccg aaggccgcgc tgctgcccag
    21661 ggcggtcagc agcgcgccgc ccgccagcgg cccgaacggc tggaccaccg aggacaggaa
    21721 ggaggccgcg ctctgcaccc ggccgagccg gtcctccggg gtgacgatca gcagggtgga
    21781 gaggaagccg atgctggcga ccgtcgagag gcccatgcag agcgcgcaga gcaggccggc
    21841 cagcagcggg ctgctgaccc aggccagcgc ggcggccgtc aggacgcagc tccagcaggt
    21901 gatgacgatg agcgtccgga catggcggtc gggcgccagc cggggcgcga gcagggcgcc
    21961 gactagggcg cccgccgaga cgcaggtgat gacgaacccg ccgccgaggc cggagcgccc
    22021 gccctcggag aagacggcga gcgcggtgaa ggtgagggcg ccgaacgcga agttcatgcc
    22081 gaggccgaag acgagcagca ccgtgcgcag atagggcagc tgccacagga aggcgagccc
    22141 ggcggtgagt tcgcggcggc tgaacaccga accggccttg gtcctggcct ccgagcgggt
    22201 ccgcacgagg gccacgcaga cggtcgagat gagcagtccg acgaactggg cgacgaacgg
    22261 cagggcctgg tgcacgccga acagcgcacc gccgaccagc gggccgacca gccggaccgt
    22321 ggaggtacgc gcctggagcc gggcggtcgc cgtgcccatc tggtccggcg gcacgaccgc
    22381 gcgcatcagc ccgaaggcgg cgggggcgta gacgctgttc agcacggcgc cggcggtcgc
    22441 gacgagcagg acgagcgcca tgggggcgtg cccgttccac acggcgaggg tcagggcggt
    22501 gaccgccgcc agactcccca cgtcgcacag ccgcatcagc cggcggcgtt cgacccggtc
    22561 ggccatcacc ccgccgggca gcatcgtgat cagcacggcg cagacggaca cggtccccac
    22621 cgcgccggcc tgcacggcgg atccggtctc ccggaggatc agcaggggca gcgcgagggc
    22681 gcccatctgg ctgcccagaa cggcgaagag gccgctcatc cagagcagcc ggaaatcccg
    22741 gttggagcgg agcggcgtgg ccatcggggg ctcccggagg tcggcggaca gggcattgca
    22801 gggcatgggc gaggactcgg gtcaggacta gggccaggac gcgggtcagg acatgggtga
    22861 ggacatgggt gaggtggcgg ggcaggggcg tacgaagcgc ggcggggcgg ctccggtgtt
    22921 cgcggagccg ccccgtaccg cctgtccccg cctgtccgcc ggccgggcgc cgcgggggcg
    22981 aggcgtcggc ctcggcccgc cgcggcgcac ggcccggtgt gcccggcgcc gcgatcggcg
    23041 ccgcgttgcg cctgcggtca gcgctgcgat tcgacgacgc tcagcacgct gatgcagttg
    23101 ccgtcggtcg tgtcgccgcc ctggacggac gtctcctgga ggtccaggac ggagtgcgcc
    23161 tcgacctcgg gggtctcgtt ggtctcgtcg ccggccggct tggtgttctc ggacatggtc
    23221 gtctccatcc actcgtcact tggtcactgc ggaacgaccg gactccccgg ctgcggaagg
    23281 gccttgggcg tccggtttgc ggggtcagtt ctcgacgacg ctgagcacgc tgatgcagtt
    23341 gccggggggc gcgatgatgt cgcggtcgcc gtggacggcg gtctcctgga ggtccaggac
    23401 ggagtgcgcc tcgacctcgg gggtctcgtt ggcgtcgtcg gcggcgggct tcgtgttctc
    23461 ggacatggtg gtctccatcc actcgtcact gcgggaccgg ggcccgtggg gaacgcccct
    23521 cggtgtccgg tgcggcgggc cggtgcctgc cgttgccgag aaagttagga agccgggcct
    23581 ggtgatcgct tcggcggcgg tatggcgtcg gtatcgggcc agttcgggcc cgtccggagc
    23641 gggccgggac cgcctcccga gcctccggcg gcggtccgga catccgcccc gacctgggcc
    23701 cataccgcct ccgaagcgat tccggaccgt ccgcgaaccg gttccgcaca gcctgggtac
    23761 gcgcccgacg cgcaccggcc ccgaaggagg cggcccgcat ggaactcgcc gaactcgtcg
    23821 cacggcggcc cttcccggcc gccggtctgc tcatcggcct cacccggcgc tgcccgttgc
    23881 gctgcgcgca ctgctcgacc gggtcggacc tgttcacccg acaggagccg gacggcggtc
    23941 aactggagcg gttcgtcggc tcgttcaccg aggagaaccg gcccgacgtc gtcatgctca
    24001 ccggcgggga gccgctgctg ctgcccgcgc tcgcggagcg gctgagcacg ctggcacgcc
    24061 gcgccgggtc ccgtaccgca ctgctcagcg gcatgttctt cgcccggagc ggaagcggcc
    24121 ggagcgggag cgccagggac gggagcaccg ggcggcggcg cagtgggcgg tacggcggtc
    24181 ggcgcggtgc ggcgattcct cccgcgatcc tgcgcgcgat ccgctcggtc gaccatttct
    24241 cggcctccct cgacgtccac cacgaacgcg aggtcccgcg cgccgacgtg ttccgcgccc
    24301 tgcaccggat ccgggcggag ggcgtggccg tgagcctgca cctgaccggg accggcgcgg
    24361 ccgatccgta tctcgccggc ctcacccggg cggtggagga ggagttcggc gggcaggtcc
    24421 cgtgcctggt caacgaggtg cggccgttcg gccgggccgc ctcctgggcc cggcccgccc
    24481 gcagcggccc ggacccggcg gcggcgtcgc cgtgctcgat ggccgcctgg ccggtggtcg
    24541 ccttcgacgg ccgcgtgctg gcctgctgca accaggacac cgtcgaccgg cggccggtcc
    24601 cggcccatct ggacctcggg cacatcggcg ccgacgactg ggcgaccgta cgccgccggg
    24661 cgctggagtc cccggtgctg cggatgctcc gcacggtcgg gcccacgcat ctggccgccc
    24721 ggtacggctc cggccccccg gcgggctcct actgcgacgg ctgccgggcg ctgggcggcg
    24781 acgaggcggc gatggccggg gcccaggcgg tggcgggcgg tgcggccggt gcgctgctgg
    24841 acctgacggc ggcggtgcgc gggtcccgcg agggcgcgca gggcgtcgtg cgccgccacg
    24901 gctgcgcggc gtacgcaccg ctggtcgtcg cgggcgggcc ggccctgccg gagagcgaag
    24961 cggaggaggt ccgatgagcg cacccgcccc cacctccgcg ggcgcatcac tcgggcgtac
    25021 cggggcctcc gcacgtctgc gggtcaaact cctgctgctg gagccggagt tccgggacgc
    25081 gacgcaccac atgtggcgca ccgaagggct gttgccgcgc taccggacgt atctgtgcac
    25141 catgcacgcc gtcatccgcg cctccgtccc gctgatggag ctggccctgc gccgagcccg
    25201 ccaactggat gcttccggcg acctgttggc ggcgccgctg gccgcgtatc tggaggagca
    25261 catccgggag gaggcgggcc acgacgactg gctgctggac gacctccggg cggcgggcgg
    25321 cacgcccgag gacgcgctcg gcccgctgcc ctcgccgttg accgcctcgc tcgtcgggtc
    25381 ccagtactac tggatcgagc accatcaccc ggtcgccctg ctcggctaca tcgccgtact
    25441 ggagggctac gcgcccgccc ccggcctcac cggccgcatc gcccggctga ccggactgcc
    25501 cgccgccgcg ctgcggaccg tacgggagca ctcggtgctc gacacggagc acctggacga
    25561 gctgtacgcg ctgctggacc ggctgccgct cggccgggag cgggaagccg ccgtggcggt
    25621 cagcgcgctg cactccctcg acgcgctcac ccggctgttc gtccggctcg ggcgctccgc
    25681 accggcgccg tcgctgcggg gagccggacc tgtcccaccg atgggagtca caccatgacc
    25741 ggaccacccg agaacggcga acggaccgtg ctgcccgacg cgttgtacga agcgggcttc
    25801 cccgtggacc tcctcaccga ggagcagcgc gaggtgctga gcgggctgac gccggaggaa
    25861 ctggcgctgc tgctcgatgt gaagagccgg ctggacgccg tcggtcccga ggtacaggcg
    25921 cacggcgaga tcgccggcgg cgcgctgttc tgaccggcga ccgatcagcg gtacgggccc
    25981 gtagccggcc atcgaacgcc ggtagcgggc ccgtacccgc ccgacatcgg agagaaggac
    26041 ccgccatgaa ctgcctcgcg tgccggcagg atctgccgcc gacggcccgt ttctgttcct
    26101 cctgcggaac accgtgcgcg accgccgcgg gtgccacgga caccgccggc ccgccggctg
    26161 ccgccgcgac cgcttccgcc gtcgccccgg ccggtgacga acgcaagccg gtgaccgtgc
    26221 tgttctgcga tctcgtcggg tccaccgcgc tgtccggggt gctcgatccg gagacgctgc
    26281 ggacggtgac cctgcggtac ttcgaggcga tgagcgcgga gatcgtggcg cggggcggca
    26341 ctccggagaa gttcatcggg gacgcggtga tggcggtgtt cggcgtgccg gtggtccgtg
    26401 acgacgacgc ccgccgggcg ctggcggcgg cgctcgggat gcgccgggcg ctggcccggc
    26461 tgaacgagga gctgaccgcc accctcggca tcgagctggc cacccgcgtc ggcgtcaaca
    26521 ccggtcaggt ggtggcgggt tcggacgcga ccgcccggca ggccctggtc tccggggaga
    26581 ccgtcaacat cgccgcccgg ctggagcaga acgcgggccg gggcgagatc ctgatcggcc
    26641 cggggacgct gctcgccgcc ggtccgacgg tgcgcgccga gcccaccggg ccgctgcggc
    26701 tgaagggcaa gcgggacagc gtggaggcct accggctgct cgcgctgggc gcggacgacc
    26761 ccgagctgct gcgccgcttc gacgtcccct tcgtcggccg cgacgccgag cggcaggcgc
    26821 tggacgccgc cctggaacgg gccgtcgacg gcggtggcgc cgggctgctg cgggtcaccg
    26881 gggaggcggg catcggcaag acccggctgg tacgggagtg gctggcgggg cggtccgcgt
    26941 ccggggcgct ggtgtacggg gcggggcggt gccgcagtta cggggaccac ggcaccctcg
    27001 cggcgctggc cgacgcggtg cgttcactgg tcggtccccc ggcgggtcag tcggcaggcc
    27061 ctccggcagg tcggtcggcg ggtcagtcgg cggttcctgc ggtgggtccg gcggtggatc
    27121 cggcagtgga cagagcgcag ggcggagccg acgggccggc ggtcgacggg ccggcggtcg
    27181 acgggctggc ggtcgacgac gcgatggccc tgctctccgg gggcctgctg cgcgacggca
    27241 cgccgaacgc gcccttcgag gacatgtgcg cggccctgac ggcggtcctg gaacgggccg
    27301 cccgtatccg cccggtcgtg ctggtgctgg acgactggca cgcggcggcc ccgctgctgg
    27361 tccgcacggt gcaccggctg acggacggct cggggtgcgc gggcgtgctg gtgctctgcg
    27421 ccgggcggcc ggacggaccg ggcgaggaca gcgaaccccc ggccggtgcg ggccacctcc
    27481 agctcaccgg cctcccccgc gaggaggcgg cccggctcgc cgccggtctc gccggtgcgg
    27541 acggcgggac tgccccggtg gacgaccggg tcctggcacg ggccggcggc aatccgctct
    27601 acctggaaca gctcctggtc ggcgaccggg aggacccggc gaccgcttcc cgccccggcg
    27661 gcggcccggc ccccggcgag gaactgccgc ccacgctcca ggccctcctc ggcgcccgca
    27721 tcggggcgct ggcccgggcg gagcgcgggg tggtggacct ggccgccgtg atcggccggg
    27781 agttcaccgc gccggagctg gtccggctgg agctctccgt gcaggccggg gagggccacg
    27841 gccccggtcc gctcacgggc gcggccggcc ccgaacaccg gcggcgcgtc gaggaggcgc
    27901 tggcggtgct gggccgccgc cggctggtgg agtcggggcc gccgggcggc cgggaggagg
    27961 cggcgtaccg gttcagcagc gggctggtcc acgaggtcgc gtacgcctcg ctgtccaagc
    28021 gggccaaggc ggaccgccat gcctgggcgg cggagctgcc cagcgtgctg cgcgccggcg
    28081 acggtgcggt gggcggccat ctggagcgcg cctaccgcta ccgcgccgag ctgggtctgc
    28141 tggacgacgc ggcccggcgg ctgcgcgacc gggccgccgc cgcgctgggc cgggccgggg
    28201 cgcaggccgc cgcccggtcc gacctgcact gggcgcacgg gctgctggaa cgcgcggtgg
    28261 acctgtgccc aggcgatccg gcggcggcac ggcggctcgg cgaggtccgc gtcgcgctgg
    28321 gccgcaccgg agaaggggcc gaactgctgc gccgggtacg ggactcgggg gccgacgcgg
    28381 tcgaggcggc gcacgcccgg ctcgcgctcg cggtgctgga tccggccgcc gcgcccggcc
    28441 ccgccgccgt ggcccgtacc gtactgccgg tcttcgaggc ggccggcgac tcgaccggcc
    28501 gggcccgcgc gcatctgcgg ctcgcccagc agttccagcg gtccgggcgg cacgaggagg
    28561 cggagcggga ccaggcgcgg gcgctggagc acgccgtgct ggccggtgcg gagccggagc
    28621 gggccggggc gctcggcgcg atcggcatct cgctgtggcg cgggccggtt ccggtgcccg
    28681 ccgcggtggt tcgctgccgg acgctgctgg cggcgcacgg tgcgggccgg cccacggtcc
    28741 ggatcaccct caactgcccg ctggcggtgc tgtacgcgct ccagggccgg gccgaggagg
    28801 cgcggggctg cctggccgag gcggaacggc tggccgggaa gctggggttc gcggaggcgg
    28861 aggtcttcct gccggtgttc cgggcgacgg tggaggcgct gtccggccgg agcgccgccg
    28921 cgctggagct gctgggccgg gcggacgcgg cggcccggcg cacgggtgcg gcggggatgc
    28981 ggacggcggt ggcgctggac gcggcccgcc tggagctgga cgagggccgc gaggacctgg
    29041 ccgccgcccg gctggcgggc gtcggcgaca cctcggggct gagccgggcg gacgcggtgg
    29101 atctggcggg gctgcgggcc cggctggcgg cccggtccgc ccccgaggag gcggccgggc
    29161 acgcggaccg ggcggtccgg gcctcgctgc tcaccgattc accgctggtg caggcgacgg
    29221 ccgagctgga ccgggcgcac acgctcgccg ccctgggccg gtggccggag gccggggcct
    29281 cggcccggtc ggccggggcg cacttcacgg gcaaggggca tctgccgggg gtgcgccggg
    29341 tctccgggtt cctcgcgcac ccgcctctgg ccatggccac gacgagggag aggagctgac
    29401 cgatgacgac cacggaaccg gcaccggcgc aggcacaggc ggaatcggta cggccccggg
    29461 cgcgtacggc cccggggcag ggcctgacct ggagtctgcg cgggcgcggc cccgacgacg
    29521 taccggtgct cgcggacgcc ggacccccgc tcggccgccc caccgggccc gccaccggcc
    29581 gcggcgtacg cgtctgcgtg gtggactcgg gtgtggagcg ggaccatccg ctgatcggcc
    29641 cgctggccgg ttcctgggtg gtcgtcaagg acggggagag cggcgagatc gcggtcgagc
    29701 cgacgaccac cggggacacc tgcggccacg gcaccgcgtg cgcgggcatc gtccgccgga
    29761 ccgccccgga gtgcgagatc cacagtgtgc gggtgctcgg ggagcggttc tccggcaccg
    29821 gcgacgtcct catggccggg ctgcgctggg cggtggagca gcgcttcgac gtggtcaacc
    29881 tcagtctgtc gacgacccgt acccggttcg cgcaggagct gcacagcctg gccgacagcg
    29941 cctacttcgc ccgtacggtg atcgtcgcct cggcccacaa caccccggtg gagagcttcc
    30001 cctggcggtt cgcctcggtg atctcggtgg gcagccacca ggaggacgat cccgaactgc
    30061 atctgtacaa cccggatccc ccggtggagt tcttcggccc gggccagaac gtgaccgtgc
    30121 cgtggctggg cggccggacg atccgcacca cggggaacag cttcgccacg ccgtacgtcg
    30181 ccgggctctg cgcccgcgtc ctgtccgcgc atccgcggat gacggccttc cagctcaaga
    30241 acgccctcta tctgtccgcg gccaatgtgc gccccgcacc gcgtccttct tccactccgg
    30301 caggagatat ccgtgatgac tccgagaact gattccgcca cctccttctc cgccaccgcc
    30361 acggtcgccg acgcgccgcg cagcgagctg ctccagtcgg tcgtcgacgt ggcccgcgcc
    30421 atcttcgggg ccgaggccag ttcggtcttc ctgctcgacg aggaggcgga cgagctggtc
    30481 ttccaggccg tgtccgggca gggcgaggag ttcctcgtgg gccgccggtt cccggccggg
    30541 cgcgggatcg ccgggtgggt ggcgacctcc ggcgagccga tggtggtgga cgacctgagc
    30601 gccgatccgt ccttcgaccg ttcgctggcg gagtcgaccg cgtatgtgcc gaacgccctg
    30661 atggcggccc cgctcatcag cgacgcccgg atcctcggcg tcctggaggt gctggatccg
    30721 tccccgcagg cccggtcggg cgtccgggag ctggatctgc tcgcgatgtt cgcccggcag
    30781 gccgccgccg ccctgcgggt gctcacgccg gagcgggtgc gcgaggccga gcagcgcgcg
    30841 gtgtccgccg ggggcgcgct ggagggtgcg cggcgcgagg acgcgctgaa actgctgggt
    30901 agcctggagc gactgctgcg gggcgtcggc tgaggtcacc ggcgccaccg gcgtccggga
    30961 gtagccaccg gcccggcggg caggagcggg gcgtcggcac caagggaagg acacgcacga
    31021 tgaagctcgc tttctccacg ctcggagtgc ccggtacgcc ggtcgccgag gtcgtccggc
    31081 tcgccgccga ccacggctac cagggggtgg agctgcgcgt ccatccggag gagccggtgc
    31141 acctggggct ctcctcgctg gaacgggccg atgtggtcga ggcgttcaag gccggcgggg
    31201 tggagatcct ggcgctcgcc ggttatgtga aggcggccgc cgagggcgac gacgaggcgg
    31261 tcctcgcgga actggccgag ctggtgaagc tcgcccgcga cctgggcgcg tcctatgtcc
    31321 gggtgttccc cggcggcggc gaccaggagc aggcggaggc cgacgcgacg gccgcccggc
    31381 ggctcggggc ggcggccccg gccgccgccg acatgggcgt gagcatcctg ctggagaccc
    31441 atgactcgca ccgggcgggc ctcgacgtcg cccgggtcgt c
//
