LOCUS       NZ_CP079114            22536 bp    DNA     linear   CON 06-SEP-2024
DEFINITION  Streptomyces sp. WY228 chromosome.
ACCESSION   NZ_CP079114
VERSION     NZ_CP079114.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. WY228
  ORGANISM  Streptomyces sp. WY228
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8286721)
  AUTHORS   Qin,S.
  TITLE     Volatile organic compounds produced by endophyte Streptomyces sp.
            WY228 mediate plant growth and salt stress tolerance by activating
            hormonal signaling and anthocyanin biosynthesis,
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 8286721)
  AUTHORS   Qin,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUL-2021) Key lab of biotechnology of medicinal
            plants, Jiangsu Normal University, No. 101 Shanghai Road, Xuzhou
            221116, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Canu v. 1.5
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 100.0x
            Sequencing Technology             :: Oxford Nanopore
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_019287315.1-RS_2024_09_06
            Annotation Date                   :: 09/06/2024 06:02:41
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,303
            CDSs (total)                      :: 7,213
            Genes (coding)                    :: 7,059
            CDSs (with protein)               :: 7,059
            Genes (RNA)                       :: 90
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 155
            CDSs (without protein)            :: 154
            Pseudo Genes (ambiguous residues) :: 0 of 155
            Pseudo Genes (frameshifted)       :: 83 of 155
            Pseudo Genes (incomplete)         :: 99 of 155
            Pseudo Genes (internal stop)      :: 10 of 155
            Pseudo Genes (multiple problems)  :: 36 of 155
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 03:35:29
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2107436
            Orig. end                         :: 2129972
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP079114.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22536
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lassopeptide"
                     /region_number="10"
                     /rules="(PF13471 and Asn_synthase or micJ25 or mcjC)"
                     /tool="antismash"
     cand_cluster    1..22536
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /kind="single"
                     /product="lassopeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22536
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12536](+)"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12536
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
     misc_feature    complement(238..249)
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 19.28"
                     /tool="antismash"
     gene            complement(612..3608)
                     /locus_tag="KV381_RS09045"
                     /old_locus_tag="KV381_09045"
     CDS             complement(612..3608)
                     /EC_number="2.7.7.42"
                     /EC_number="2.7.7.89"
                     /GO_function="GO:0008882 - [glutamate-ammonia-ligase]
                     adenylyltransferase activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003969544.1"
                     /locus_tag="KV381_RS09045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_09045"
                     /product="bifunctional [glutamine synthetase]
                     adenylyltransferase/[glutamine
                     synthetase]-adenylyl-L-tyrosine phosphorylase"
                     /protein_id="WP_030622536.1"
                     /transl_table=11
                     /translation="MTTVPGRRSSTFTRLLRHGFTDPSAAEQLLDLDALASVRSDPVLL
                     EALGATADPDLSLRGLVRIVEAETADERQVLLDTLVTAKPLRDRLLGVLGASEALGDHL
                     ARHPRDWQALVTYEAIDLHPGVAEFERGLADAVDPDSLRVAYRRCLLTLAARDVCGTTD
                     LAQTAAELADLATATLRAALAIARTAAPEDAAQCRLAVVAMGKCGGRELNYVSDVDVIF
                     VGEARDGVDETKAMQAATRLAAHMMRICSETTAEGTIWEVDANLRPEGRNGPLVRTLSS
                     HLAYYQRWAKTWEFQALLKARAVAGDPELGAEYVEAVSPLVWGAADRENFVPDVQKMRR
                     RVVDNIPADRIERELKLGPGGLRDVEFAVQLLQLVHGRSDASLRSGSTLEALRALAEGG
                     YVGRADAAQLDEAYRFLRSMEHRIQLYRMRRTHLVPEDEADLRRLGRSLGMRTDPVAEL
                     NKAWKRHASVVRRLHEKIFYRPLLDAVAQLAPAESRLSAKAAAHRLEALGYADPAAALR
                     HLEALSSGVSRKAAIQRTLLPVLLGWFADSADPDAGLLGFRKVSDALGKTPWYLRLLRD
                     EGAAAENLARVLSAGRLAPDLLMRAPEAVAILGDPEGLTPRTRAHLDQEVLAAVGRAGD
                     AESAVAVVRGVRRRELFRTTAADLIGSYGTEDSPAEQDHGALVDRVGSAVTDLNAATIA
                     GALRAAVRERWGDTLPTRFAVIGMGRFGGHELGYGSDADVLFVHQPREGVSDEEAGRAA
                     NAVVGEMRRLLQLPTADPPLLIDADLRPEGRTGPMVRTLKSYEAYYRRWSLVWESQALL
                     RAEPVAGDAELGRAFIELADPLRYPMEGLGEDAVREIRRLKARMESERMPRGADPTLHA
                     KLGRGGLSDVEWTVQLMQMRHGWSEPGLRTTRTREALAAACAAGLIPAEDAETLDEAWV
                     LATRVRNAVMLVRGRPGDTFPSEAREMTAVGRYLGYEPGHVGDMLDDYRRITRRARAVV
                     EERFYGAAS"
     gene            3757..4257
                     /locus_tag="KV381_RS09050"
                     /old_locus_tag="KV381_09050"
     CDS             3757..4257
                     /EC_number="1.-.-.-"
                     /EC_number="1.4.3.5"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005478480.1"
                     /locus_tag="KV381_RS09050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_09050"
                     /product="pyridoxamine 5'-phosphate oxidase family protein"
                     /protein_id="WP_218785033.1"
                     /transl_table=11
                     /translation="MTPSRRNHVHDRTPPARPWPEAAAVLTDAPLYWLSTVRPDGRPHV
                     TPLIGVWSDGALHFCTGPQERKAHNLAANPEVVLTTGANTLDSGFDVVVEGRADRVTDH
                     ERLTALAREWEAKYGSDWHFDVEDGSFVQAEAGHAQVFAVRPRTAFGFGKGEPYSQTRY
                     RFG"
     gene            complement(4242..5069)
                     /locus_tag="KV381_RS09055"
                     /old_locus_tag="KV381_09055"
     CDS             complement(4242..5069)
                     /GO_function="GO:0008276 - protein methyltransferase
                     activity [Evidence IEA]"
                     /GO_function="GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0018364 - peptidyl-glutamine methylation
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003969543.1"
                     /locus_tag="KV381_RS09055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_09055"
                     /product="putative protein N(5)-glutamine
                     methyltransferase"
                     /protein_id="WP_030622530.1"
                     /transl_table=11
                     /translation="MPVHPALSFSTALFASTVVALRRAGCVFAEDEARLLHEAAASPDG
                     LSALVERRAAGLPLEHVLGWAEFHGRRYAVDPGVFVPRRRTEFLVAQAAALAPRRAVVV
                     DLCCGSGALGVALAAASEAAELHACDVEPAAVRCARRNVGELGQVYEGDLFAPLPAALR
                     GRVDVLLANVPYVPTDDVELLPAEARVHEPRVALDGGGDGLDVMRRVAAEAPAWLAPGG
                     SLLVEASERQRDTAVGVLRAAGLSPRVLVSEELYATVLVGTAANSPFEDHPKR"
     gene            complement(5350..6900)
                     /locus_tag="KV381_RS09060"
                     /old_locus_tag="KV381_09060"
     CDS             complement(5350..6900)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1005: Drug
                     resistance transporter, EmrB/QacA"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018958159.1"
                     /locus_tag="KV381_RS09060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_09060"
                     /product="MFS transporter"
                     /protein_id="WP_030080843.1"
                     /transl_table=11
                     /translation="MSAADTAAPAGAPAAAPMDHRHVLRSLSGLLIVLFVAMISSTVVS
                     VALPQIIGSLDGTQSQYTWVVTATLLASTASTPIWGKLADLFSKKLLLQIAIGIFVVSS
                     VACGFAQSTEQLIAFRAVQGLGMGALQVLVQVIIAAMISPKERGRYNGYLGGVMAVATV
                     GGPLLGGFITDASWLGWRWCFFIAVPFTLLASVMLARTLHLVEVRRPDTKVDYLGASLI
                     AAGVSLLLLWVTFVGDDFGWLSWQSALMVGGSVVILTAAVLVEARVKEPVVPLHVVRRR
                     DPALAIVASLAVGMAMFGGAVFLGQYFQIGRGYSPTEAGLLTIPLMAGVLVSSTVAGRL
                     VSKTGKVKPFIVAGVVVLALGFLGLSFIDHRTSLVLVSAGMLGVGAGVGMSMQNLVLVL
                     QNTVPLSEIGAASGAITFFRSLGGTMGVSVLGAVLAHQVANKIADGLTKLGIDPAASGS
                     GGSTLNVAAMPPQVQDVVRAAYGEATGHIFLISAGIAVVGVIASLFLTPTKLRDSVDL"
     gene            7065..7664
                     /locus_tag="KV381_RS09065"
                     /old_locus_tag="KV381_09065"
     CDS             7065..7664
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1215: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010070505.1"
                     /locus_tag="KV381_RS09065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_09065"
                     /product="TetR family transcriptional regulator"
                     /protein_id="WP_030622527.1"
                     /transl_table=11
                     /translation="MDSSTAGPGLRERKKEATRQAVHEATLRLTVEHGFDHVTVEAVAD
                     AAGISRRTFSNYFTNKEDALLYGEEQQIRALVRTVRDRPTDEPAWPALRAAVAQFADRV
                     APPEREWAIRTRLAMRHPSLLARQLANHATLERDLAEAVATRPGPSSAPVRPIVLAAGF
                     LSSLRIAMRMWIEEDLAREPAAVIDEILDEMGRGFV"
     gene            complement(7696..8973)
                     /locus_tag="KV381_RS09070"
                     /old_locus_tag="KV381_09070"
     CDS             complement(7696..8973)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019764472.1"
                     /locus_tag="KV381_RS09070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_09070"
                     /product="twin-arginine translocation signal
                     domain-containing protein"
                     /protein_id="WP_247594934.1"
                     /transl_table=11
                     /translation="MMAPEGIGALLRGSREAAGLTREEQASVLQAAQGGKWFDPENLKR
                     WETERRLPTPIWHALLAECYGRSTEEIVRAVVASRRHRRLYRLIDQEKREEGSVVDRRQ
                     FLGVAAAATGMAGVPDISEARQGINAGLSASDGSDLAYLNGAFERHRGGYRGRPPHEVL
                     EQMKVDLDLLRELLGRPHPAAVRKDLARTAAGITGLVAVIQHDRGEQRDAVGWFATAEQ
                     AARESGDRHMLAWVLSRHAMVPLNYGAPNAAAVMAMRARAEAGRSPSAAAALAAAVTAR
                     SLASVGDREGALRAVGDARATAARLDSAQVADTWFGYPPQKHHVHLSQAFTLMGRTREA
                     YAEQESALALTKAPSVMTRALVAVDGAACVRADGDPTTAAGLALDVWRQLPPAYRGGLV
                     RSRVESLCQSLPGRTGNTLREALAGC"
     misc_feature    complement(8887..8889)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            9221..9718
                     /locus_tag="KV381_RS09075"
                     /old_locus_tag="KV381_09075"
     CDS             9221..9718
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018486775.1"
                     /locus_tag="KV381_RS09075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_09075"
                     /product="ATP-binding protein"
                     /protein_id="WP_234024590.1"
                     /transl_table=11
                     /translation="MRADTSAAISRRRLLALVSAWHLPKDEDSHLAMTTVVSELVTNAV
                     SHGAGDLLTVTVRADIGRSRLLIEVHDSSPVLPRFRRPSLDSESGRGMVLVEHLSIACG
                     AENTSRGKRVWAELALPMEPSAKRRSLYLRCASQAIVQRFLNVLRPLVRTGPGVLTAVS
                     DR"
     gene            9798..9932
                     /locus_tag="KV381_RS09080"
                     /old_locus_tag="KV381_09080"
     CDS             9798..9932
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007457608.1"
                     /locus_tag="KV381_RS09080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_09080"
                     /product="albusnodin family lasso peptide"
                     /protein_id="WP_107057946.1"
                     /transl_table=11
                     /translation="MNPLQIAENTDENDLLPVEIGEATVLTEGQGGGQSEDKRRAYNS"
     gene            10001..11818
                     /locus_tag="KV381_RS09085"
                     /old_locus_tag="KV381_09085"
     CDS             10001..11818
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Asn_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177: asparagine synthase (glutamine-hydrolyzing)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015034320.1"
                     /locus_tag="KV381_RS09085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_09085"
                     /product="albusnodin/ikarugamycin family macrolactam
                     cyclase"
                     /protein_id="WP_030080852.1"
                     /sec_met_domain="Asn_synthase (E-value: 1.9e-33, bitscore:
                     115.3, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIFGGSGSPSRPGFRPVGSRHLSSRLHTWALGAVPVRSVTSPGDR
                     RQVLILGRCGAKESDLHRLSPALPEDVAWRWPGTYTVIEESEEAVVIHTDPASARPIYL
                     VGHDDGWVWSSSARALASLTRATVDVERLACSIFLPSVPALCEGRTFFAGVGQLPPGCR
                     IVLPVDGSAPRTTTAWIPDPDESQPPAERLRTALFTSVTERVVSDPEVSCDLSGGLDST
                     SVAALAAVALPYGMRLNAITIHPEGDTAGADLRYARQAAHAYSGRINHRLLAMSAKHLP
                     YTAMSAVPATDEPAPSTITQARLMGQFRWLRQECGTRTHMTGDGGDSLFFQPPVHLADL
                     VRHGRIRRAVSEAFGWARLRRASPVPFLRDAVLVSRTARARALSELVDSIGGRRRSDHG
                     RVGWFPLLPHPSWAGAAAPALLSASALRAASAPDGMPGLDASVRTLVDEVREVARTAAA
                     DAELAAASGIDLNNPFLDPLVVDAVLRTPIDLRPPLHSYKPLLGKAMAGLLPRTVANRQ
                     TKGSFDADHYAGLRANMPELLELAHGHLAEMGLIDAAHLVPSLGQAAAGVPMPLATLEQ
                     ALSAEAWLTAHAREPEPVWTSTPAGPCHD"
     misc_feature    11525..11527
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            12051..12536
                     /locus_tag="KV381_RS09090"
                     /old_locus_tag="KV381_09090"
     CDS             12051..12536
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: PF13471"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF033537.1"
                     /locus_tag="KV381_RS09090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_09090"
                     /product="lasso peptide biosynthesis B2 protein"
                     /protein_id="WP_247594939.1"
                     /sec_met_domain="PF13471 (E-value: 1.9e-21, bitscore: 75.0,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPLSAPAPPASWGGAEHPAGLTRGTGPFSAEAAAALAATWSIKRS
                     GNRKRAMNRLIVALRASSSTTRRPASPTEAAEAVQAVRRSAWHAPVRTACLEESVAATL
                     LLATRRLSVVWCHGIAADPVRLHAWVQTVDGASVAEPPSTLAYTPALTIGARHQHRL"
     gene            12550..13086
                     /locus_tag="KV381_RS09095"
                     /old_locus_tag="KV381_09095"
     CDS             12550..13086
                     /EC_number="2.3.-.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1111: GCN5-related N-acetyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015034322.1"
                     /locus_tag="KV381_RS09095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_09095"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_050495592.1"
                     /transl_table=11
                     /translation="MGTDTCALGPYRADLVETYWRWEQDPALLVGYGRQQPVSLESRTE
                     GIAHQLRGDNIRFTVYDLATGSPVPAGVATLLPDPSVRTAEYVVMLAPEARGRGLGTVA
                     TRLVLDYAFHITNLRMVWLKVLAPNKAGVRAYEKAGFRTAGTLREAGYWLGTVCDELLM
                     DALASEFTGPSVITA"
     gene            complement(13204..13968)
                     /locus_tag="KV381_RS09100"
                     /old_locus_tag="KV381_09100"
     CDS             complement(13204..13968)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1136: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006124018.1"
                     /locus_tag="KV381_RS09100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_09100"
                     /product="GntR family transcriptional regulator"
                     /protein_id="WP_030622523.1"
                     /transl_table=11
                     /translation="MPRDTPYLKVADALRARIRAGDWAVGDKLPSRARIAEEYGVGQSV
                     AQRAMERLIIEGILEGRAGSGTYVRRARVRRRMVRSRQREQHGKSPFASAMKELDHEAD
                     WECTSTARVPASEDIAERLAIEPGDLCVVTDYEFLADGLPVQLAKSWEPMAITDGTPVL
                     LPEMGPLGKLGVVERMRSIDVNIATGIELPRPARATREQANLLGISVGDLVIEIERTYF
                     DRDGRPVETANVTVPDIRWEIAYEIRVDQPDS"
     gene            14129..14467
                     /locus_tag="KV381_RS09105"
                     /old_locus_tag="KV381_09105"
     CDS             14129..14467
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018958162.1"
                     /locus_tag="KV381_RS09105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_09105"
                     /product="hypothetical protein"
                     /protein_id="WP_030622520.1"
                     /transl_table=11
                     /translation="MLAAATGTEPRVTTGLDAFRVEADLPAELSATAHTAVLAALATAD
                     RYGHTLSRAAEYVWAEISREANVTTTESPDTAYRALLGHTMTCTACRTGAICPDATKLV
                     RVWRETRR"
     gene            14558..14854
                     /locus_tag="KV381_RS09110"
                     /old_locus_tag="KV381_09110"
     CDS             14558..14854
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007457619.1"
                     /locus_tag="KV381_RS09110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_09110"
                     /product="hypothetical protein"
                     /protein_id="WP_030080858.1"
                     /transl_table=11
                     /translation="MITLSATDTRTCEACWNAPVTAARQTPAGRDLICEECAEGDYPRR
                     VDLFPPFGIYGLTTRKLLNDGKHGSGPPKTPPNPGPPLPNPPPAPSPRGTPPV"
     gene            15142..15819
                     /locus_tag="KV381_RS09115"
                     /old_locus_tag="KV381_09115"
     CDS             15142..15819
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012381205.1"
                     /locus_tag="KV381_RS09115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_09115"
                     /product="hypothetical protein"
                     /protein_id="WP_256995028.1"
                     /transl_table=11
                     /translation="MAFGGNGSGPTAAPAPGPVDSVTQPASPSASSTPPSEDADATEPE
                     TPAATDKTPSASSSATPEADLTAPDGYAEALSTMWGLAPVPCTQHEQQLVDLDDGTSRT
                     EDEDNGAVQEPGGAELLYWPDTCTGIADYMVRALPNTRVGLLRADAPKSFDSCRAAAGT
                     GFGALALAQRPDRERRGFVEGAAVCSVTDKGAVAMAVIEHIADETTNEVSVSGPLYVWA
                     AAP"
     gene            complement(15895..17256)
                     /gene="glnA"
                     /locus_tag="KV381_RS09120"
                     /old_locus_tag="KV381_09120"
     CDS             complement(15895..17256)
                     /EC_number="6.3.1.2"
                     /GO_function="GO:0004356 - glutamine synthetase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006542 - glutamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="glnA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004931998.1"
                     /locus_tag="KV381_RS09120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_09120"
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="WP_030080862.1"
                     /transl_table=11
                     /translation="MDKQQEFVLRTLEERDIRFVRLWFTDVLGFLKSVAVAPAELEQAF
                     DEGIGFDGSAIEGFARVYESDMIAKPDPGTFQILPWRAEAPGTARMFCDILMPDGSPSF
                     ADPRYVLKRILAKTSDLGFTFYTHPEIEFFLLKNKPVDGTRPTPADSSGYFDHTPQNVG
                     MDFRRQAITMLESMGISVEFSHHEGAPGQQEIDLRYADALSTADNIMTFRLVMKQVALE
                     QGVQATFMPKPFSEYPGSGMHTHLSLFEGDRNAFYESGAEYQLSKVGRSFIAGLLKHAA
                     EISAVTNQWVNSYKRIWGGSSRAAGAGGEAPSYICWGHNNRSALIRVPMYKPGKTGSAR
                     VEVRSIDSGANPYLTYAVLLAAGLKGIEEGYELPAGADDDVWALSDAERRAMGIEPLPQ
                     NLGEAISLMEKSELVAETLGEHVFDFFLRNKKQEWEEYRSEVTAFELKNLLPVL"
     gene            17513..18205
                     /locus_tag="KV381_RS09125"
                     /old_locus_tag="KV381_09125"
     CDS             17513..18205
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007457633.1"
                     /locus_tag="KV381_RS09125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_09125"
                     /product="DUF3105 domain-containing protein"
                     /protein_id="WP_030622507.1"
                     /transl_table=11
                     /translation="MSFDPRYSQPQASDPRARSTRNRAIAIGVSAAVVAGLVAFGSYLL
                     LENSEANEKSDNASSAQDGKHPDGHGDSHDDTKGGAIEGLKSWDAAKLGRQHVAGTVDY
                     PMKPPVGGDHNASWMNCDGDVYEKPLPDVNAVHSLEHGAVWITYNDTAADAEVSKLAQR
                     VKATPFTLMSPYAAQEGAIMLSAWGKQVTVDSAGDKRVDQFLAQYVQGAQTPEPGAPCT
                     GGLATVPR"
     gene            18265..18987
                     /locus_tag="KV381_RS09130"
                     /old_locus_tag="KV381_09130"
     CDS             18265..18987
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012381204.1"
                     /locus_tag="KV381_RS09130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_09130"
                     /product="DUF305 domain-containing protein"
                     /protein_id="WP_030622505.1"
                     /transl_table=11
                     /translation="MERRRTRRVRLAAGAAVVLALLFAGAATVASARGDGSGEESGNTR
                     VPAASSADAGFARDMAVHHQQAVEMSFVVRDRTDDEDVRRLAYDIANTQANQRGMLLGW
                     LDLWELPKVAPGGEPPMAWMEGGGRHAHGGHHSDGDASGSGGGSGDGDGDGVLMAGMAS
                     RSELARLGRLDGEQAEVFFLQLMTDHHKGGVAMAEACASQCSVPAERRLARGMVEGQRS
                     ELGLMRDMLAERGAAPRS"
     gene            19307..19732
                     /locus_tag="KV381_RS09135"
                     /old_locus_tag="KV381_09135"
     CDS             19307..19732
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018511825.1"
                     /locus_tag="KV381_RS09135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_09135"
                     /product="CBS domain-containing protein"
                     /protein_id="WP_030622500.1"
                     /transl_table=11
                     /translation="MTTAKDIMHSGARWIPAHETLDRAAQLMREHNVGALPVSANGDSD
                     RMVGIITDRDIVVGCVAKGHDPAKVTAGDLAQGTPRWIEAEAGVDAVLEEMQTHRIRRL
                     PVVENKKLVGMISEADLAQHLTEEQIAGWAEKVYSRS"
     misc_feature    19806..19821
                     /note="TFBS match to CsoR, Copper-responsive repressor,
                     confidence: weak, score: 23.35"
                     /tool="antismash"
     misc_feature    19806..19822
                     /note="TFBS match to RicR, Copper-responsive regulator,
                     confidence: weak, score: 23.3"
                     /tool="antismash"
     misc_feature    complement(19807..19822)
                     /note="TFBS match to CsoR, Copper-responsive repressor,
                     confidence: weak, score: 24.12"
                     /tool="antismash"
     gene            19833..20270
                     /locus_tag="KV381_RS09140"
                     /old_locus_tag="KV381_09140"
     CDS             19833..20270
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018511824.1"
                     /locus_tag="KV381_RS09140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_09140"
                     /product="hypothetical protein"
                     /protein_id="WP_030622498.1"
                     /transl_table=11
                     /translation="MAGTARSGSGTFGRLMLLAALLFGIVTMHTVGHPAEHSDVSAAVT
                     TTTASTAEHMVPAAPVAGPSHPAAHGSPGSDAPMGGMDPLSVCLAVLGVWGLALVGARL
                     LGARADRRPLGTPVGAGLPLALLPNPPPPISVLASVSVLRI"
     misc_feature    complement(20277..20288)
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 18.46"
                     /tool="antismash"
     misc_feature    20329..20347
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 19.64"
                     /tool="antismash"
     misc_feature    complement(20340..20353)
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 17.78"
                     /tool="antismash"
     gene            20343..21959
                     /locus_tag="KV381_RS09145"
                     /old_locus_tag="KV381_09145"
     CDS             20343..21959
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003969531.1"
                     /locus_tag="KV381_RS09145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_09145"
                     /product="multicopper oxidase family protein"
                     /protein_id="WP_030622496.1"
                     /transl_table=11
                     /translation="MPMQPTRRSVLGAALAVAGTGALAACSGGGSGHGGSHSPGGGAQD
                     SGTYVSPGGKEVRAAEAARGSGPVREVSLTATRTRLDLGGGTTVASWAYGDRLPGREVR
                     VTAGDTLALTLANHLPAPTSLHWHGLALRNDMDGVPGLTQRDIAPGADFGYRFAVPHPG
                     TYWFHPHSGVQQDRGLYAPLIVEDPKEPLAYDREWVVVLDDWVDGVDGSTPDAVLKELS
                     RGMSSGGMSSEGTSEGGGGMDHGAHTMSGAETEEPGRAGPSRMMMGARSALLGGDAGDV
                     AYPHYLVNGRVPEDPSSFSARPGDRIRLRIINAGGDTAFRVALGGHRMTVTHTDGFPVR
                     HATGDALLLGMGERYDVLVTAEDGVFPLTALAEGKKASALAVLRTGSGRAPAASVRPEE
                     LDGKLIEAGRLAPDPAVALARRAPDRTIQMRLTGGMARYDWAFDGQPYSAEQRRPVEAG
                     ERVRVVFDNGTAMWHPLHLHGHTFALGGNAAGARKDTAIVLPHRSLTVEFDADNPGLWM
                     VHCHNVYHAEAGMMAVLGYRS"
     misc_feature    22064..22084
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: medium, score: 28.77"
                     /tool="antismash"
ORIGIN
        1 cacgagacgt ggggctcgat ggcgtcgggc aacttcaaga acatgtcgaa ccagtacgcg
       61 gcgatgccgt cgatgcacat cggctggtcg ctctggtgcg gcctgacgat cttcgccctg
      121 gcctcggcgc cctgggcccg cattctgggc ctgctctacc cgacgctcac cctcgtggtc
      181 atcgtggcca ccgccaacca cttctggctg gacgcggtgg gcggcatggc ctgcctcgcg
      241 ttcggttacg cgatctcccg cgtctggtac ggctcactgc cgcaccggct gccgaagcgg
      301 gtgcccaccg ggtccggcga cgggaagagc cggctgaccg ggctgcgcgc cgccagactg
      361 ccgcgcccgg cgtcggagcc gaagccggag acggagccgg agacggagac ggaaacggcc
      421 ggggcgcgca gggcgtagtc ctcgtacggc gaggaacggg gtgtggggcg gacgtcgtgt
      481 ccgccccaca ccctgttcgc ccggtcgggg ccgctacccc cggtgcccgt cagcccgccc
      541 ggcgcttgag ggcgccctta tcagcccctc ctgcgtttga ggagcggggt ccgggccccg
      601 ggagcgaacg cttaagacgc cgccccgtag aaccgctcct ccaccaccgc ccgagccctc
      661 cgagtgatcc gccgatagtc gtccaacatg tccccgacat gccccggctc gtaccccagg
      721 taccgcccca ccgccgtcat ctcccgcgcc tcggacggaa acgtgtcgcc cggccgcccc
      781 cgcaccagca tcaccgcgtt gcgcacccgc gtggccagca cccacgcctc gtccagcgtc
      841 tccgcgtcct ccgccggaat cagccccgcc gcacacgcgg cggccagcgc ctcgcgcgtc
      901 cgcgtcgtcc gcagccccgg ctccgaccac ccgtgccgca tctgcatcag ctgcacggtc
      961 cactcgacat cgctcagccc gccccgcccc agcttcgcgt ggagcgtggg gtccgcgccg
     1021 cgcggcatcc gctcggactc catccgcgcc ttgagccggc ggatctcgcg tacggcgtcc
     1081 tcgccgagcc cttccatcgg ataccgcaac ggatcggcca gctcgatgaa cgcgcgcccc
     1141 aactccgcgt cgcccgccac cggttcggcc cgcagcagcg cctggctctc ccagaccagc
     1201 gaccagcgcc ggtagtaggc ctcgtacgac ttgagcgtgc gcaccatcgg cccggtcctg
     1261 ccctccggcc gcagatcggc gtcgatgagc aacggcgggt cggcggtcgg cagttggagc
     1321 agtctccgca tctcccccac gaccgcgttg gccgcccgcc ccgcctcctc gtcgctcacg
     1381 ccctcgcgcg gctgatggac gaagaggacg tccgcgtcgg agccgtaacc cagctcgtgc
     1441 ccgccgaagc ggcccatgcc gatgacggcg aaccgggtcg gcagcgtgtc gccccaccgc
     1501 tctcggacgg cggcccgcag cgcgcccgcg atggtggcgg cgttgaggtc ggtgacggcc
     1561 gagccgacgc ggtcgacgag cgccccgtgg tcctgctcgg cggggctgtc ctcggtgccg
     1621 tacgagccga tgaggtcggc ggccgtcgta cggaacagct cgcgccggcg caccccgcgc
     1681 accaccgcga cggccgactc cgcgtccccg gcccgcccca ccgcggccag cacctcctgg
     1741 tccaggtggg cccgggtgcg gggggtgagc ccctccggat cgccgaggat cgccaccgcc
     1801 tccggggccc gcatgagcag gtccggggcg aggcggccgg cggagaggac ccgggcgagg
     1861 ttctccgcgg ccgcgccctc gtcgcgcagg agccgcaggt accacggggt cttgccgagc
     1921 gcgtcggaca ccttgcggaa gccgaggagc ccggcgtccg ggtcggcgga gtccgcgaac
     1981 cagccgagca gcaccggcag cagcgtgcgc tggatggcgg ccttgcggga gaccccggag
     2041 gagagggcct ccaggtgccg cagggcggcg gccgggtcgg cgtacccgag ggcctccagg
     2101 cggtgggccg cggccttcgc gctgagccgg gactcggcgg gggccagctg ggcgacggcg
     2161 tccagcaacg gccggtagaa gatcttctcg tgcagccgcc gtacgacgga ggcgtgccgc
     2221 ttccacgcct tgttcagctc ggccaccggg tcggtgcgca tcccgagcga ccggccgagc
     2281 cgccgcagat ccgcctcgtc ctcggggacg aggtgggtgc ggcgcatccg gtagagctgg
     2341 atccggtgct ccatggagcg caggaagcgg tacgcctcat cgagctgcgc ggcgtccgca
     2401 cgtccgacgt aaccgccctc ggcgagcgcc cgcagcgcct ccagggtgga gccgctgcgc
     2461 agcgaggcgt cactgcggcc gtgcaccaac tggaggagct ggacggcgaa ttcgacgtca
     2521 cggaggccgc cggggccgag cttcagctcg cgctcgatgc ggtcggcggg gatgttgtcg
     2581 acgacgcggc ggcgcatctt ctgcacgtcg gggacgaagt tctcccggtc ggcggcgccc
     2641 cagacgagcg gcgacaccgc ctcgacgtac tccgcgccca gctcggggtc gccggccacc
     2701 gcgcgggcct tcaacagggc ctggaactcc caggtcttgg cccagcgctg gtagtaggcg
     2761 aggtgcgagc tgagggtgcg caccagcggc ccgttgcgcc cctcggggcg gaggttggcg
     2821 tcgacctccc agatggtgcc ctcggcggtg gtctcggagc agatccgcat catgtgggcg
     2881 gccagccggg tggcggcctg catcgccttg gtctcgtcga ccccgtcgcg cgcctccccg
     2941 acgaagatca cgtcgacgtc ggagacgtag ttcagctccc gcccgccgca cttgcccatc
     3001 gccacgacgg cgagccggca ctgcgccgcg tcctcgggcg cggccgtgcg ggcgatggcg
     3061 agcgcggcgc gcagggtggc ggtggcgagg tcggccagtt cggcggcggt ctgggcgagg
     3121 tcggtggtgc cgcacacgtc ccgggcggcg agggtgagca ggcaccggcg gtaggcgacc
     3181 cgcagcgagt ccgggtcgac cgcgtcggcg agcccccgct cgaactcggc gaccccgggg
     3241 tgcaggtcga tcgcctcgta ggtcacgagc gcctgccagt cgcgcggatg ccgggccaga
     3301 tggtcgccga gcgcctccga cgcgccgagc accccgagga gccggtcgcg caggggtttg
     3361 gcggtgacga gggtgtcgag cagcacctgc cgctcgtccg ccgtctcggc ctccacgatc
     3421 cggaccagtc cgcgcaggga cagatccgga tcggcggtgg ccccgagcgc ctccaggagg
     3481 accggatccg accgtacgga ggcgagcgcg tccaggtcga ggagctgctc ggcggcggac
     3541 gggtcggtga atccgtgccg cagcaaccgg gtgaacgtac tgctcctgcg ccccggcacc
     3601 gtcgtcattg cacgctctcc cgccgcccga accgatctgc gtaactgctc ggccgcttcg
     3661 ttcgccggcg tcacagctct ccgagcctag tcctgtgccg atgaattcgg ggcgggggcg
     3721 gagtccaccc atggggaaag cacctgacag caccccttga cgccctcccg gaggaaccat
     3781 gtccacgacc gaacgccccc ggcccgcccg tggccggagg cggccgccgt gctcaccgac
     3841 gccccgctgt actggctgtc cacggtccgc ccggacggcc gcccccatgt cacgccgctg
     3901 atcggcgtct ggtccgacgg cgccctccac ttctgcacgg gcccgcagga gcgcaaggcg
     3961 cacaacctgg cggccaaccc cgaggtggtc ctgacgacgg gcgcgaacac cctggactcc
     4021 gggttcgacg tcgtggtgga gggccgggcg gaccgggtga cggaccacga gcggctgacc
     4081 gccctggccc gggagtggga ggcgaagtac ggctccgact ggcacttcga cgtcgaggac
     4141 ggcagcttcg tccaggcgga ggcgggccac gcccaggtgt tcgcggtccg cccccgtacg
     4201 gccttcggtt tcggcaaggg ggagccgtac agccagacgc gctaccgctt cgggtgatcc
     4261 tcgaaggggc tgttcgccgc cgtcccgacg aggacggtgg cgtacagctc ctcggagacc
     4321 aggacccggg ggctcagccc ggcggcgcgc aggaccccga ccgccgtgtc gcgctgccgc
     4381 tcgctcgcct ccaccagcag gctgccgccc ggcgcgagcc atgcgggcgc ttcggcggcg
     4441 acccggcgca tgacgtcgag gccgtcgccg cccccgtcca gggcgacgcg cggttcgtgg
     4501 acgcgggcct cggcgggcag cagctcgacg tcgtcggtgg ggacgtaggg gacgttggcc
     4561 agcagtacgt cgacccggcc gcgcagggcg gcgggaagag gagcgaagag atcgccctcg
     4621 tacacctggc ccagctcgcc gacgttgcgc cgggcgcagc gcacggcggc gggttcgacg
     4681 tcgcaggcgt gcagttcggc ggcctccgac gcggcggcca gggcgacgcc gagcgcgccg
     4741 gacccgcagc agaggtcgac gacgacggcc cggcggggcg cgagggcggc ggcctgcgcc
     4801 accaggaatt ccgtacgccg gcggggtacg aagacgccgg ggtccacggc gtagcggcgg
     4861 ccgtggaact ccgcccagcc caggacgtgt tcgaggggca gcccggcggc gcggcgctcg
     4921 acgagggcgg acagtccgtc cggggatgcg gcggcctcgt ggaggaggcg ggcctcgtcc
     4981 tcggcgaaga cacagccggc gcgacggagg gcgacgacgg tggaggcgaa gagggcggtg
     5041 gagaaggaga gagcggggtg aaccggcata cgagcgaagc ctttcgggaa aaccgatggg
     5101 cgctccgcga tcgtcctaga ccgtccgatc agccgctgcg ggtgctggtg cttgtgctgg
     5161 cgctgctgct gccggtcgtc cgatgtgatc gcgcggggtg agcacccagc ctgatccagc
     5221 ggtaatgggt ctcacctcct cggtcgatct catcgttccc gtggcgtacg ggggtcgcaa
     5281 cagtacaaca gcccgcttcc gcaccccgtg cgagggcgcg aaagcgggcg gtacgagccg
     5341 tgcgggggct cagagatcca cactgtcccg cagcttggtg ggcgtcagga acagcgaggc
     5401 gatgacaccg accacggcta tgccggccga gatgaggaag atgtgcccgg tggcctcccc
     5461 gtaggcggcc cggacgacgt cctggacctg gggcggcatg gcggcgacgt tgagggtgga
     5521 tccgccggat ccggaggcgg ccggatcgat tcccagcttc gtcagcccgt cggcgatctt
     5581 gttcgcgacc tgatgggcga ggaccgcgcc gaggacggag acgcccatgg tgccgccgag
     5641 ggagcggaag aaggtgatgg ccccgctggc cgcgccgatc tcgctgagcg gaacggtgtt
     5701 ctggaggacg agcaccaggt tctgcatcga catgccgacc ccggcgccga cgccgagcat
     5761 gccggccgac accaggacga gcgaggtccg gtggtcgatg aaggagaggc cgaggaagcc
     5821 gagggcgagg acgaccacac cggcgacgat gaacggcttg accttgccgg tcttcgacac
     5881 gaggcgtccg gcgacggtgg aggagacgag cacgcccgcc atcagcggaa tggtgaggag
     5941 tcccgcctcg gtcggcgagt agccgcgtcc gatctggaag tactgcccga ggaagaccgc
     6001 accgccgaac atggccatgc cgacggcgag gctggcgacg atggcgaggg cggggtcccg
     6061 gcggcgtacg acgtgcagcg gaacgaccgg ctccttgacg cgcgcctcga cgagaacggc
     6121 cgccgtcagg atgacgacgc ttcccccgac catcagtgcg ctctgccagg agagccagcc
     6181 gaagtcgtcg ccgacgaagg tgacccagag gagcaggagg ctgaccccgg cggcgatgag
     6241 ggaggcgccg aggtagtcga ccttggtgtc gggccggcgg acctcgacga ggtgcagggt
     6301 gcgggcgagc atcacggagg cgagcagcgt gaagggcacg gcgatgaaga agcaccagcg
     6361 ccagccgagc caggaggcgt cggtgatgaa cccgccgagc agcggaccgc cgacggtggc
     6421 gacggccatg acaccgccga ggtagccgtt gtagcggccg cgctccttcg ggctgatcat
     6481 cgcggcgatg atcacctgca caagcacctg gagcgcgccc atcccgagcc cctggacagc
     6541 gcggaaggcg atcaactgct cggtggactg ggcgaaccca caggcgaccg acgagacgac
     6601 gaagatcccg atggctatct ggagcagcag cttcttgctg aacaggtcgg cgagcttgcc
     6661 ccagatcggg gtggaggccg tggaggccag gagggtcgcg gtgacgaccc aggtgtactg
     6721 cgactgcgtg ccgtcgaggg acccgatgat ctgcgggagg gcgaccgaga ccacggtgct
     6781 gctgatcatc gccacgaaca ggacgatgag cagcccgctc agggaccgca ggacgtggcg
     6841 gtggtccatg ggtgcggcgg cgggggcccc ggccggggcg gcggtgtctg ctgcgctcac
     6901 gcgcaacctc cggaaagttc gtacgagagg cccgtacgag gcggtggcca cgggctggtc
     6961 cgcgcgcgac gccggtacgg gagggagaag acttcaccat acatgcacac tgcgcaattt
     7021 tgcccactgc gcaacaatct cggaccccgg gggataatgc ccccatggac agcagcaccg
     7081 cgggaccggg cctccgggaa cgcaagaagg aagccacccg ccaggccgtg cacgaggcga
     7141 ccctgcgcct gacggtggaa cacggcttcg accacgtgac ggtcgaggcg gtggcggacg
     7201 cagccggaat ctcccgccgg acgttctcca actacttcac caacaaggag gacgccctcc
     7261 tctacggcga ggaacagcag atcagggccc tggtccgcac ggtccgcgac cgccccaccg
     7321 acgaacccgc ctggccggcc ctgcgcgcgg cggtggccca gttcgcggac cgggtggcac
     7381 cccccgaacg tgagtgggcg atccgcaccc gcctggcgat gcgccacccc tccctcctgg
     7441 cccgccaact ggccaaccac gccaccctcg aacgcgacct ggccgaagcc gtggccaccc
     7501 gcccgggccc gtcctccgcc ccggtccgcc cgatcgtcct ggcggcgggc ttcctgtcct
     7561 cgctccggat cgcgatgcgc atgtggatcg aggaggacct ggcacgggag ccggcggcgg
     7621 tgatcgacga gatcctggac gagatggggc gggggttcgt gtgagggtga gtgatctggc
     7681 cgtccccgca aggcctcagc agccggccag tgcctcgcgc aacgtgttcc ccgtacgccc
     7741 gggaagtgac tggcacaacg actcgacccg ggagcggacc aagccgcccc ggtaggcagg
     7801 gggaagctga cgccagacat cgagggcgag gccggccgca gtggtcggat cgccgtccgc
     7861 ccggacgcag gccgcaccat cgacggcgac cagcgcgcga gtcatgacgg acggggcctt
     7921 ggtgagcgcg agtgcggact cctgctcggc ataggcctcg cgggtccgcc ccatgagcgt
     7981 gaacgcctgg gaaaggtgca cgtggtgctt ctgcggcggg tagccgaacc aggtatcggc
     8041 cacctgcgcc gaatcgagtc gcgccgcggt ggcgcgggcg tcaccgaccg ctcgcagcgc
     8101 tccctcccgg tccccgacgg aggcgagtga cctcgcagtc acggccgcgg ccagagcagc
     8161 ggcagcactc ggagaccggc cggcttcggc tcgggctcgc atggccatca ctgcggcggc
     8221 gttcggggct ccgtagttca gcggcaccat cgcgtgccga ctgagcaccc aggcgagcat
     8281 gtggcgatcg ccggactcgc gagcggcctg ctcggccgtg gcgaaccagc cgaccgcgtc
     8341 ccgttgctcg cctcgatcat gctggatgac agccaccaag ccggtgatgc cggcggccgt
     8401 gcgcgccagg tctttgcgca ccgcagccgg gtgagggcgt ccgagaagct cccgcagcag
     8461 gtcgagatcg actttcatct gctccagcac ttcatggggc ggacgccccc gatatccacc
     8521 gcgatgacgt tcgaatgccc cgttcagata ggcgagatca ctgccgtccg aggcggacag
     8581 gcccgcattg atcccctgcc gcgcctccga gatgtccggc acccccgcca ttcccgtagc
     8641 cgccgctgcc acgccgagaa actgacgtcg gtccactacc gagccctcct ccctcttttc
     8701 ttgatcaatc agccgataga gccttcgatg acgtcggctg gccacgacgg cacgcacgat
     8761 ttcctccgtg gacctgccgt agcactcggc gagcagtgcg tgccagatcg gcgtgggcag
     8821 gcgccgctcg gtctcccagc gcttcaaatt ctccgggtcg aaccactttc cgccctgagc
     8881 cgcttgtaac accgacgctt gttcttcacg tgtcaggcca gccgcttcac ggcttcccct
     8941 cagcagtgcc ccgatgcctt ccggtgccat catgcccgtc ccccaagctc ctggaagtgt
     9001 catgtcgatt tctggccccc caaagcggcc ccccggcagg aatttgcacc actggatggc
     9061 ccacgactgt tgtcccgtaa cggagttgag taaacaccag caggcgtaac gaccggatgg
     9121 aacaagcctt tcccgagagt gggcatccca ttcgagtcca gggcgtgttc cgacgaaagg
     9181 gattctcgtg aggcatgtga gctgccaaag cttctacttg gtgcgcgccg acacttcggc
     9241 ggcgatcagc cgtcggcggc tgctcgccct cgtcagcgcc tggcacctgc ccaaggacga
     9301 ggacagccac ctggccatga ccacggtggt ctcggaactg gtcaccaacg ccgtgtctca
     9361 cggagccggc gatctgctca cggtgaccgt gcgtgcggac atcggccgaa gcaggctctt
     9421 gatcgaagtc cacgacagct ccccggttct gccccggttc cgacgcccga gccttgactc
     9481 cgaaagcggc cggggcatgg tgctcgtcga gcacctgtcg atcgcctgcg gagccgagaa
     9541 cacctcgcgg ggcaagcggg tctgggcaga gctggccctg cccatggagc catcggccaa
     9601 gcgacggtcc ctctaccttc gttgcgcatc gcaagccatc gtccagcggt tcctcaacgt
     9661 gctccggcct ctcgtccgta cggggcccgg ggtcctgacg gctgtcagcg accgctgaca
     9721 gatcacgttc ctcacacccg acccggtccg ttcagcccgg cgtcaagtca cccatcgccc
     9781 aacagaagga gaacgtcatg aacccacttc agatcgcgga gaacaccgac gagaacgacc
     9841 tgctccctgt cgagatcggt gaagcgaccg tgctcaccga gggtcagggc ggcggccaga
     9901 gcgaagacaa gcgccgcgcc tacaacagct gatcccttct cgtgggtgcg ggccccagcg
     9961 cccgcaccca cgggttgacc tcgactctgg agttctgacc atgatcttcg gtggtagcgg
    10021 ttccccttcc cgaccgggat tccgacccgt gggatctcgc catctctctt cgcggctcca
    10081 cacctgggcg ctcggtgccg ttccggtccg gtccgtgacc agtcccggcg atcggcgaca
    10141 ggtgctcatc ctcgggcggt gcggagcgaa ggaatccgat ctgcaccgcc tgagtccggc
    10201 gctgcccgag gacgtcgcct ggaggtggcc aggcacctat acggtcatcg aggaatccga
    10261 agaagccgtc gtgatccata ccgacccggc ctccgctcgc cccatctatc tcgtcggcca
    10321 cgacgacggg tgggtatggt ccagctcagc ccgggctctg gcctcactca ctcgtgccac
    10381 ggtggacgtg gaacgcctcg cctgctcgat cttcctgccg tcggttcccg cgctctgcga
    10441 gggacgaaca ttcttcgcgg gtgtcggaca actcccacca gggtgccgga tcgttctgcc
    10501 ggtcgacgga agcgcccctc ggacaacaac agcgtggatt ccagatccgg acgagtctca
    10561 accacccgca gagcgtttgc gcacggcgct cttcacatcc gtcaccgaga gagtcgtgtc
    10621 ggatccagag gtctcctgtg acctctcggg cggactcgac tccacctctg tcgctgctct
    10681 cgccgctgtc gctctcccgt acggcatgcg gctcaacgcc atcacgatcc atcccgaggg
    10741 cgacaccgcg ggcgcggacc tgcgctacgc acgccaggca gcccatgcgt actccgggcg
    10801 gatcaatcac cgtctgctgg cgatgtcggc gaagcacctg ccgtacaccg cgatgtctgc
    10861 cgttccggcg accgacgaac cggctccctc cacgatcacg caggcccggc tcatggggca
    10921 gttccgctgg ttgcggcagg aatgcggaac ccgcacccat atgacgggcg acggcggcga
    10981 cagcctgttc ttccagccac ccgtccacct tgccgacctc gtccgccacg gccgcatcag
    11041 gcgtgccgtg agcgaggcat tcggctgggc caggctgcgc cgcgcgtctc ccgtaccctt
    11101 cttgcgcgac gctgtcctcg tctcgcggac ggcccgcgct cgcgccctgt ccgaactcgt
    11161 cgattccatc ggtggaaggc gacgcagcga ccatggaagg gtcggctggt ttcccctgct
    11221 gccccatccc tcgtgggccg gtgccgccgc gcctgccctg ctgagcgcca gcgcgctccg
    11281 agccgcctcg gccccggacg ggatgcctgg cctcgacgcc tcggtacgca cgctggtgga
    11341 cgaggtccgc gaagtcgcac gcaccgctgc cgcggacgcc gaactggccg cggcctcggg
    11401 gatcgatctc aacaaccctt tcctcgaccc gttggtcgtg gacgccgtac tccggacgcc
    11461 catcgacctg cgtccccctc tccactccta caaaccgctt ctgggcaagg cgatggctgg
    11521 tctattacct cgtaccgtcg caaaccggca gaccaaaggc agcttcgacg cggaccacta
    11581 cgcaggcctc cgggccaaca tgcccgaact ccttgaactg gcacacgggc accttgcaga
    11641 aatggggctg atcgatgccg cacatctggt tccgtccctg ggccaggccg cagccggcgt
    11701 gcccatgccg ctggccactc tcgagcaggc tctcagcgcc gaggcctggc tgacggcgca
    11761 cgctcgagaa cctgagcccg tgtggacctc cacgcctgcg ggaccgtgtc atgactgacg
    11821 tttcgccgtt cgctcacgcc tcccggcacg tccatgccgt cgccttcccc cacgtcctgg
    11881 ttctcatcga ctaccggacc ggccatgtgc agtgtctgct gccgaagagc gcggctcact
    11941 ggcaggaggc ggcccgatcc ggtcggctca ccgcaatgcc gccaccactg gcggcccacc
    12001 tgattcgcac aggggttctg tcccccacgc agaagcacac gccgtgggac atgccgctct
    12061 cggcaccagc gcctccggca agttggggcg gggccgagca tccggcgggg ctcacacggg
    12121 gaaccggccc cttcagcgcg gaggcagccg ctgctctcgc cgcaacatgg agcatcaagc
    12181 ggtccggtaa taggaagcgg gcgatgaacc ggctcatcgt ggctctgcgg gcgtcctcct
    12241 ccacgacgcg tcgaccggct tctcccacag aggcagcgga ggcagtccag gccgttcgcc
    12301 gttccgcgtg gcatgcgccc gtaagaactg cctgcctgga agaatcggtc gctgccacgc
    12361 tcctgctcgc gacccgacgg ctctccgtcg tctggtgtca tggaatcgcc gcggaccccg
    12421 tccgactgca cgcctgggtg cagactgtgg acggggcttc ggtcgccgaa ccgccctcga
    12481 ccctcgcgta cacaccagcg ctgaccatcg gagcccgcca tcagcaccgc ctctgaaccc
    12541 gttctctgga tcggcaccga cacctgtgcg ctcggcccgt atcgggcgga cctggtggag
    12601 acgtactggc gttgggaaca ggacccggcg ctcctggtcg gctacggacg ccagcagccg
    12661 gtgtccctgg agtcgcgcac ggagggcatc gcccatcaac tgcgcgggga caacatccgc
    12721 ttcacggtgt acgacctcgc caccggcagt ccggtaccgg cgggtgtggc cacgctgctg
    12781 cccgacccgt ccgtacgcac ggcggagtac gtcgtgatgc tcgcccccga ggcacgcgga
    12841 cgcggactgg gcacggtcgc cacccggctg gtcctcgact acgcgttcca catcaccaac
    12901 ctgcggatgg tctggctcaa ggtcctcgcc cccaacaagg cgggggtgcg cgcctacgag
    12961 aaggccggct tccgcaccgc gggaaccctt cgcgaggcgg gctattggct gggcacggtc
    13021 tgcgatgaac tcctgatgga cgcgctggca tcggagttca ccggaccgtc ggtcatcacg
    13081 gcctgacccg ccgaagccgg gcgcgcggtt acggacaacg ggttacgagt tacgggtccg
    13141 gctcacggac gaccgaagat gccggacccg aaaggagccc ggcatcaaca ccctctcccc
    13201 cgctcaggaa tccggctgat cgacgcggat ctcgtacgcg atctcccacc ggatgtccgg
    13261 cacggtgacg ttcgccgtct cgacagggcg gccgtcccgg tcgaagtacg tgcgctcgat
    13321 ctcgatgacc aggtcgccga cggagatccc gagcagattc gcctgctcac gcgtcgcgcg
    13381 ggccgggcgg ggcagctcga tgccggtggc gatgttcacg tcgatggaac gcatgcgctc
    13441 gacgacgccg agcttgccga gcggccccat ctccgggagg aggaccggcg tgccgtcggt
    13501 gatggccatc ggctcccagc tcttggcgag ttgtacgggc aggccgtcgg cgaggaactc
    13561 gtagtcggtc acgacacaga ggtcgccggg ctcgatcgcc agccgttccg cgatgtcctc
    13621 cgacgcgggg acgcgcgccg tgctggtgca ctcccagtcc gcctcgtgat cgagctcctt
    13681 catcgctgag gcgaaagggc tcttgccgtg ctgctcgcgc tgacgtgagc ggaccatgcg
    13741 ccggcgcacg cgggcccggc ggacgtacgt accggatccg gcgcggcctt cgaggatgcc
    13801 ctcgatgatc agacgttcca tggcccgctg cgccacggac tggccgacgc cgtactcctc
    13861 ggcgatccgg gcccgggacg gcagtttgtc ccccaccgcc cagtcgccgg cccgaatgcg
    13921 agcccgcaga gcatccgcca ccttcaagta cggcgtatca cgtggcattt gagcagctcc
    13981 gtgtgttcgg cgtcgatatg ggcgtcgctg ttgacaaagc taacccatca ggttgaagct
    14041 gaatactcag cattacatgg agtgacattc ggttcaccag gggagaagtg tgcgctctgc
    14101 acaagcgcgg gttgcggcgc tgaccggcat gctcgccgcc gccacaggca ccgaaccgcg
    14161 cgtcaccacc ggcctggacg ccttccgcgt cgaggccgat ctccccgccg agttgagcgc
    14221 caccgcccac acggccgtcc tggccgccct ggccacggcg gaccgctacg gccacacgct
    14281 cagccgcgcc gccgaatacg tctgggccga aatcagcaga gaggcgaacg tgaccacgac
    14341 cgaatccccg gacacggcgt accgcgccct gctcggccac accatgacct gcaccgcatg
    14401 ccggaccggc gcgatctgcc ccgacgcgac gaagctcgtc cgcgtctggc gggagacccg
    14461 tcggtgagcg ccaccagcca catcagcccc accagagacg gaggcacctg atgcgcagca
    14521 cccaccaggc gttaccggcc ccacccggga ggcccggatg atcaccctct ccgccacgga
    14581 cacccgcacc tgcgaggcgt gctggaacgc cccggtcacc gccgcccgac agacccccgc
    14641 cggccgtgac ctgatctgcg aggagtgcgc ggagggcgac tacccgcgcc gcgtcgacct
    14701 cttcccgccg ttcggcatct acggcctgac gacccgcaag ctcctgaacg acggcaaaca
    14761 cggcagcggc cccccgaaaa ccccaccgaa cccgggccca ccgctgccca acccgccacc
    14821 ggccccgtca ccgcgaggaa caccgccggt gtagcgccac cggccaccac ctgtcggcct
    14881 gtacccgtcg cgcggcgggt acggggcgta gatgccgcga aacccaggtg caccgcgcct
    14941 catgatcgct acgctgggcc gtcgcacgaa gtcggcttgc cggaggggga catgggtaca
    15001 ccaccagggt caggagcgcc ggttccacca ccaccgccgc cgtacccgcc cgcacctccc
    15061 acgcctccgc gcaccgaccc tccgcgatgg gcgtggtggg tcggcggtat cgccatcccc
    15121 ctggtcggca tcctggtgac cgtggcgttc gggggcaacg gctccggacc gaccgccgca
    15181 cccgcccccg gcccggtcga cagcgtcacg cagcccgcct cccccagcgc gtccagcacc
    15241 cctccctccg aggacgcgga cgcgacggag cccgagacgc ccgccgccac ggacaagaca
    15301 ccgtccgcct cctcatccgc gacgccggaa gccgacctca cggcgcccga cgggtacgcg
    15361 gaggcgctca gcacgatgtg gggtctcgcg cccgtcccgt gcacgcagca cgaacagcaa
    15421 ctcgtcgacc tcgacgacgg caccagccgg acggaggacg aggacaacgg cgcggtccag
    15481 gagcccggcg gtgcagagct gttgtactgg cccgacacct gcaccggaat cgccgactac
    15541 atggtgcgcg cactgcccaa cacccgcgtg ggactcctcc gcgccgacgc cccgaagtcg
    15601 ttcgactcct gccgggccgc ggcaggcacg ggtttcggcg cgcttgcgct cgcgcagcgc
    15661 cccgatcgtg agcggcgggg attcgtcgaa ggcgccgcgg tgtgctccgt cacggacaag
    15721 ggcgctgtgg cgatggcggt gatcgagcac atcgccgacg agacgaccaa cgaagtctcg
    15781 gtcagcgggc ctctctacgt ctgggccgcg gcaccctgac cacaccagga tgacgccgct
    15841 acgactgcgg gccgacagtg cgccactgtc ggcccgcagt cttacttcca ggcgctacag
    15901 caccggcagc aggttcttca gctcgaaggc cgtgacctcg ctgcggtact cctcccactc
    15961 ctgcttcttg ttgcgcagga agaagtcgaa gacgtgctcg cccagcgtct cggcgaccag
    16021 ttcgctcttc tccatcagcg agatcgcctc gcccaggttc tgcgggagcg gctcgatgcc
    16081 catcgcgcgg cgttccgcgt cggagagggc ccagacgtcg tcgtcggcgc cggccgggag
    16141 ttcgtagccc tcctcgatgc ccttgaggcc cgcggcgagc aggaccgcgt aggtgaggta
    16201 cgggttggcg ccggagtcga tggagcggac ctctacgcgg gccgagccgg tcttgccggg
    16261 cttgtacatc gggacgcgga tgagggcgga gcggttgttg tggccccagc agatgtacga
    16321 gggggcctcg ccgcccgcgc cggccgcgcg ggaggagccg ccccagatgc gcttgtagga
    16381 gttgacccac tggttggtga cggccgagat ctccgccgcg tgcttcagga ggcccgcgat
    16441 gaaggagcgg ccgaccttgg agagctggta ctccgcgccc gactcgtaga acgcgttgcg
    16501 gtcgccctcg aagagggaga ggtgggtgtg catgcccgaa cccgggtact ccgagaacgg
    16561 cttcggcatg aacgtggcct gcacgccctg ctccagcgcc acctgcttca tcaccaggcg
    16621 gaacgtcatg atgttgtccg ccgtggagag cgcgtccgcg tagcggaggt cgatctcctg
    16681 ctggcccggg gcgccctcgt ggtggctgaa ctccaccgag atgcccatcg attccagcat
    16741 cgtgatcgcc tggcggcgga agtccatgcc cacgttctgc ggcgtgtggt cgaagtagcc
    16801 ggagctgtcc gccggggtcg ggcgggtgcc gtcgaccggc ttgttcttca gcaggaagaa
    16861 ctcgatctcg gggtgggtgt agaaggtgaa gcccaggtcg gacgtcttgg ccaggatccg
    16921 cttcagtacg tagcgcgggt ccgcgaagga cggcgagccg tccggcatca ggatgtcgca
    16981 gaacatccgc gcggtgcccg gggcttccgc gcgccagggc aggatctgga acgtgcccgg
    17041 gtccggcttg gcgatcatgt ccgactcgta gacccgggcg aagccctcga tcgccgagcc
    17101 gtcgaagccg atgccctcgt cgaaggcctg ctccagctcg gccggagcga cggcgacgga
    17161 cttgaggaac ccgaggacgt cggtgaacca cagccgcacg aagcggatgt cgcgctcctc
    17221 aagggtcctg aggacgaatt cctgctgctt gtccattgcc acatccttgc agttcagacg
    17281 gtccgtgcac caccgcccgg ggtaggggga cacagccagt atcgcgaccc gggatttcac
    17341 ccacattacg cactcggtgt gagagggagc actcggccac ccactacgat cggcgaccgt
    17401 ggcgcacggg ggcggcgacc gggtgacgac cggcattcac gcccgtccgc gcgcaccggt
    17461 ccacggaccg ttctcccgcc tcccggcccc cttcgcagaa ggacgcgacg acatgagctt
    17521 cgacccccgg tactcccagc cgcaggcctc cgacccgcgc gctcgctcca cccgcaaccg
    17581 ggccatcgcc ataggggtca gcgccgccgt cgtggccggt ctcgtcgcct tcggctcgta
    17641 cctgctgctg gagaactccg aggcgaacga gaagtccgac aacgcctcct ccgcccagga
    17701 cggcaagcac cccgacgggc acggcgactc ccacgacgac accaagggcg gggccatcga
    17761 ggggctgaag tcctgggacg ccgcgaagct cggccgccag cacgtggcgg gcaccgtgga
    17821 ctatccgatg aagcccccgg tcggcggcga ccacaacgcg tcctggatga actgcgacgg
    17881 cgacgtatac gaaaagcccc tcccggacgt caacgccgtg cactccctgg agcacggcgc
    17941 ggtctggatc acgtacaacg acacggccgc cgacgcggag gtctccaagc tcgcccagcg
    18001 cgtcaaggcc accccgttca cgctgatgag cccgtacgcc gcccaggagg gcgcgatcat
    18061 gctctccgcc tggggcaagc aggtcaccgt ggactccgcc ggcgacaagc gggtggacca
    18121 gttcctcgcc cagtacgtcc agggcgcgca gacccccgag cccggagccc cctgcaccgg
    18181 cgggctggcc acggtgccgc ggtgacggcc cgggacgtca ccgacgagcg gtcggcagct
    18241 gacggccacg accctcacgt cctcgtggag cggcggcgga cccggcgcgt ccgcctggcc
    18301 gccggtgccg ccgtcgtcct cgccctgctc ttcgcggggg ccgccacggt cgcctccgcg
    18361 cgtggcgacg gcagtggaga ggagagcgga aacacgcgtg ttcccgctgc ctcgtccgcc
    18421 gacgccgggt tcgcccggga catggccgtc caccatcagc aggccgtcga gatgtccttc
    18481 gtcgtccgcg accgcacgga cgacgaggac gtacgccgtc tcgcctacga catcgccaac
    18541 acccaggcca accagcgcgg catgctgctc ggctggctcg atctgtggga gctgcccaag
    18601 gtcgcgcccg gcggggagcc gcccatggcc tggatggaag gcgggggccg gcacgcccac
    18661 ggcgggcacc actcggacgg tgacgccagc ggtagtggtg gcggcagcgg tgacggtgac
    18721 ggtgacggcg tgctcatggc cggtatggcc agtcgctccg agttggcccg gctcgggcgg
    18781 ctcgacggcg agcaggcaga ggtgttcttt ctccagttga tgaccgacca ccacaagggc
    18841 ggtgtcgcca tggccgaggc ctgtgcgtcg cagtgctcgg ttccggccga gcggcggctc
    18901 gcccggggca tggtcgaggg gcagcggtcc gagctggggc tgatgcggga catgctcgcc
    18961 gagcggggcg ccgcgcctcg gtcctgagcc gatgagcggg cttgagccgg ggcgggccgg
    19021 agccgatgcg ggcctgagcc gatgcgggcc gcgcccggac ggcgggtgag cggtcgccgg
    19081 tgaccgtggc cggtgccggt ggccggtgcc tggtggccgg tgccggtggc cggtggccgc
    19141 gggtgcggat gcgggtgcgg gtgcgggtgc gggtgcgtca gcttgcgtcc tgtccgcagc
    19201 gcactcgaac gggtggttgc ggtcgcgcgg ccccggcggg cccacgacga tgggttgcgc
    19261 tcggggccgt acggcagtgc catcggcacg caggaggaaa tcccccatga cgaccgccaa
    19321 agacatcatg cacagcgggg cccgctggat cccggcccac gagacgctcg accgtgcggc
    19381 gcagctgatg cgcgagcaca acgtgggcgc gctgcccgtc tccgccaacg gtgactcgga
    19441 ccggatggtc ggcatcatca ccgaccgcga catcgtggtc ggctgtgtgg ccaaggggca
    19501 cgatccggcg aaggtcacgg ccggcgatct cgcgcagggc acgccccgct ggatcgaggc
    19561 ggaggccggt gtggacgcgg tcctggagga gatgcagacc caccgcatcc gtcggctgcc
    19621 cgtcgtcgag aacaagaagc tggtcggcat gatcagcgag gccgatctcg cccagcacct
    19681 caccgaggag cagatcgcgg gctgggccga gaaggtctac tcccgcagct gacacacgtg
    19741 tacgacagtg gcccggcacc ccatggcccg ctccggcgga gggtgccggg cctccgtatg
    19801 tgcgtatacc caccgggggt agggtggccc gcatggcggg tacggcgcgg agcggcagcg
    19861 ggacgttcgg gcggctgatg ctgctcgccg cgctgctgtt cgggatcgtc accatgcata
    19921 cggtcggaca tccggcggag cacagcgatg tatccgcagc ggtcaccacg actaccgcct
    19981 ccaccgccga gcacatggtc ccggccgcac ccgtcgccgg cccgtcgcac ccggcggcgc
    20041 acggctcccc cggctccgac gcccccatgg gcggcatgga tccgctctcc gtctgcctcg
    20101 ccgtcctcgg cgtctggggc ctcgcgctcg tcggcgcccg gctgctcgga gcgcgtgcgg
    20161 accggcggcc cctcggtacg ccggtggggg cggggcttcc gctcgcgctg ctgccgaatc
    20221 cgccgccgcc gatatcggtg ctcgccagcg tttcggtgct gcgtatctag gagtgggcgt
    20281 tcacctccgc ccttctccct ttcctcttcc tcgaaccaca gttcctcaga ggtgtatgca
    20341 gcatgcccat gcaacccacc cgacgctccg tgctcggcgc cgctctcgcc gtcgccggta
    20401 ccggagccct cgccgcctgt tccggcggcg gcagcggcca cggcggctcc cactcccccg
    20461 gcggcggcgc ccaggactcc ggtacgtacg tctcccccgg cggcaaggag gtccgggcgg
    20521 ccgaggcggc gcgcggctcc gggcccgtgc gcgaggtctc cctcaccgcc acccgtaccc
    20581 ggctcgacct cggcggcggt accaccgtcg cctcctgggc gtacggggac cggctgcccg
    20641 ggcgcgaggt gcgggtgacg gcgggcgaca cgctcgcgct caccctcgcc aaccatctgc
    20701 cggcgcccac ctccctgcac tggcacgggc tcgccctgcg caacgacatg gacggggttc
    20761 ccgggctgac ccagcgggac atcgcaccgg gggccgactt cggctatcgg ttcgccgtgc
    20821 cgcatccggg gacgtactgg ttccacccgc actccggcgt ccagcaggac cgggggctgt
    20881 acgcgccgct catcgtcgag gacccgaagg agccgttggc gtacgacagg gagtgggtcg
    20941 tcgtcctcga cgactgggtc gacggggtgg acgggtcgac gcccgacgcg gtgctgaagg
    21001 agctgtccag agggatgagt tccggaggga tgagttccga ggggacgagc gagggcggcg
    21061 gcgggatgga tcatggcgcg cacaccatgt ccggagcgga gacggaggag ccgggccgtg
    21121 ccgggccctc ccggatgatg atgggcgccc gcagcgcgct gctcggcggt gacgccggtg
    21181 atgtcgccta tccgcactac ctcgtcaacg ggcgggtgcc ggaggatccg tcctccttct
    21241 ccgcgcggcc cggtgaccgt atccggctgc ggatcatcaa cgccggtggc gacaccgcct
    21301 tccgggtcgc gctcggcggg caccggatga ccgtgacgca caccgacggg ttcccggtcc
    21361 ggcacgccac gggggacgcg ctgctgctgg ggatgggcga gcggtacgac gtcctcgtca
    21421 ccgccgagga cggggtcttc ccgctcaccg ccctggccga ggggaagaag gcgtccgcgc
    21481 tcgccgtgct gcggaccggg agcgggcgtg cgcctgccgc ttccgtacgg cccgaggagc
    21541 tggacgggaa gctgatcgag gcggggcggc tggcgccgga cccggcggtg gcgctggcga
    21601 ggcgtgcgcc ggaccggacg atccagatgc ggctcaccgg cgggatggcg cggtacgact
    21661 gggccttcga cgggcagccg tacagcgcgg agcagcggcg tccggtcgag gcgggcgaac
    21721 gggtgcgggt cgtcttcgac aacgggacgg ccatgtggca tccgctccat ctgcacgggc
    21781 acacgttcgc gctcggcggg aacgccgccg gggcccgtaa ggacaccgcg atcgtgctgc
    21841 cgcaccggtc gctgaccgtg gagttcgacg ccgacaaccc ggggctgtgg atggtccact
    21901 gccacaacgt ctaccacgcg gaggcgggga tgatggcggt cctcggctat cgcagctagc
    21961 cggacacccc ctgggtccca gggcttctgc gggtcggcgc acatagctgc ctccacctgc
    22021 ggtttcggcg ggccggaaca gattttgccc ggcccgccgg gacatcgcgt cagaaagacg
    22081 attacactgg cggacgtgcc tcaactacgc ctcgcactga atcagatcga ctcgaccgtc
    22141 ggcgacctcg ccggcaactc cgaggcgatc gtccactgga cccggcacgc cgccgagcag
    22201 ggcgcccacc tggtggcgtt ccccgagatg gtgctgaccg gataccccgt cgaggacctg
    22261 gccctgcggt cgtccttcgt cgaggcctcg cgacaggcgc tgcgcgcgct ggccgcccgg
    22321 ctcgacgcgg agggcttcgg cgaactgccg gtcgtcgtcg gctacctgga ccgctccgag
    22381 cacgccgcgg cgcgctacgg gcagcccgcc gggtctccgc gcaacgccgc cgccgtgctg
    22441 caccgcggcg ggatcgcgct caacttcgcc aagcaccacc tgccgaacta cggcgtcttc
    22501 gacgagttcc ggtacttcgt gccgggcgac tcgatg
//
