LOCUS       NZ_CP079114            10399 bp    DNA     linear   CON 06-SEP-2024
DEFINITION  Streptomyces sp. WY228 chromosome.
ACCESSION   NZ_CP079114
VERSION     NZ_CP079114.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. WY228
  ORGANISM  Streptomyces sp. WY228
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8286721)
  AUTHORS   Qin,S.
  TITLE     Volatile organic compounds produced by endophyte Streptomyces sp.
            WY228 mediate plant growth and salt stress tolerance by activating
            hormonal signaling and anthocyanin biosynthesis,
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 8286721)
  AUTHORS   Qin,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUL-2021) Key lab of biotechnology of medicinal
            plants, Jiangsu Normal University, No. 101 Shanghai Road, Xuzhou
            221116, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Canu v. 1.5
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 100.0x
            Sequencing Technology             :: Oxford Nanopore
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_019287315.1-RS_2024_09_06
            Annotation Date                   :: 09/06/2024 06:02:41
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,303
            CDSs (total)                      :: 7,213
            Genes (coding)                    :: 7,059
            CDSs (with protein)               :: 7,059
            Genes (RNA)                       :: 90
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 155
            CDSs (without protein)            :: 154
            Pseudo Genes (ambiguous residues) :: 0 of 155
            Pseudo Genes (frameshifted)       :: 83 of 155
            Pseudo Genes (incomplete)         :: 99 of 155
            Pseudo Genes (internal stop)      :: 10 of 155
            Pseudo Genes (multiple problems)  :: 36 of 155
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 03:35:29
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1668170
            Orig. end                         :: 1678569
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP079114.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..10399
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="ectoine"
                     /region_number="8"
                     /rules="ectoine_synt"
                     /tool="antismash"
     cand_cluster    1..10399
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="ectoine_synt"
                     /kind="single"
                     /product="ectoine"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..10399
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[5000:5399](+)"
                     /cutoff="20000"
                     /detection_rule="ectoine_synt"
                     /neighbourhood="5000"
                     /product="ectoine"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..5399
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="ectoine_synt"
                     /neighbourhood="5000"
                     /product="ectoine"
                     /protocluster_number="1"
     gene            complement(340..1440)
                     /locus_tag="KV381_RS07090"
                     /old_locus_tag="KV381_07090"
     CDS             complement(340..1440)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Amidohydro_1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006123619.1"
                     /locus_tag="KV381_RS07090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_07090"
                     /product="amidohydrolase family protein"
                     /protein_id="WP_030627401.1"
                     /sec_met_domain="Amidohydro_1 (E-value: 5.9e-18, bitscore:
                     63.9, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDQEEQRVLRVKGRVLVGPDEVRDELWAVDGRITYERPPGADRA
                     VTVTGWALPGLVDAHCHVGLDAHGPVDAATAEKQALADREAGTLLIRDAGSPSDTRWVD
                     DREDLPKIIRAGRHIARTRRYIRNYAHEIEPGDLVAYVAREARRGDGWVKLVGDWIDRD
                     AGDLTACWPRGELAAAIAEAHRLGARVTAHCFAEESLTDLVEAGIDCIEHATGLTEETI
                     PLFAERGVAIVPTLVNIATFPDLAAGGEAKFPRWSAHMRQLYERRYDTVRAAYDAGIPV
                     YVGTDAGGSLAHGLVAGEVAELVKAGIPPLEALSATAWGARRWLGRPVLEEGAPADLVV
                     YDEDPRADVRVLAAPRHIVLNGRVIG"
     gene            1529..2635
                     /locus_tag="KV381_RS07095"
                     /old_locus_tag="KV381_07095"
     CDS             1529..2635
                     /NRPS_PKS="Domain: Aminotran_5 (16-286). E-value: 3.6e-28.
                     Score: 90.4. Matches aSDomain:
                     nrpspksdomains_KV381_RS07095_Aminotran_5.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_5"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1139: aminotransferase class V"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006123620.1"
                     /locus_tag="KV381_RS07095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_07095"
                     /product="alanine--glyoxylate aminotransferase family
                     protein"
                     /protein_id="WP_030627406.1"
                     /sec_met_domain="Aminotran_5 (E-value: 6.3e-22, bitscore:
                     76.7, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTHPFLDLPPLTADRFAAIERSVARLLATEQDVVITQGEALLPLE
                     GCIRSGARPGSTALNVVTGPYGQTFGNWLRDCGAQVVDLAVPFHTAVTAGQVAEALAAH
                     PEIDFVSLVHAEAATGNTNPVAEIGEVVRAHGALFMLDAVASVGAEPLLPDAWGVDLCV
                     IGAQKAMGGPAGVSAVSVSARAWERMAANPAAPRRSYLSLLDWKERWIDGGRKALPHAP
                     AQLEMLGLEACVARIEDTGLDTVMARHASAAAATRAGAVALGGGLEPYVHAARDAAPVA
                     TTLRAPAGTDAAALVAHALAADPSLPLVAGGGALSKEMIRVNHYGADATRDAVLSSLAA
                     LGSALTDAGLRVDIDAARAAVSETWPGR"
     aSDomain        1577..2386
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_KV381_RS07095_Aminotran_5.1"
                     /evalue="3.60E-28"
                     /label="KV381_RS07095_Aminotran_5.1"
                     /locus_tag="KV381_RS07095"
                     /protein_end="286"
                     /protein_start="16"
                     /score="90.4"
                     /tool="antismash"
                     /translation="AAIERSVARLLATEQDVVITQGEALLPLEGCIRSGARPGSTALNV
                     VTGPYGQTFGNWLRDCGAQVVDLAVPFHTAVTAGQVAEALAAHPEIDFVSLVHAEAATG
                     NTNPVAEIGEVVRAHGALFMLDAVASVGAEPLLPDAWGVDLCVIGAQKAMGGPAGVSAV
                     SVSARAWERMAANPAAPRRSYLSLLDWKERWIDGGRKALPHAPAQLEMLGLEACVARIE
                     DTGLDTVMARHASAAAATRAGAVALGGGLEPYVHAARDAAPVATTLRA"
     misc_feature    complement(2728..2742)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 15.79"
                     /tool="antismash"
     misc_feature    complement(2751..2768)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 14.5"
                     /tool="antismash"
     misc_feature    2760..2777
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 14.75"
                     /tool="antismash"
     misc_feature    complement(2762..2777)
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: medium,
                     score: 17.62"
                     /tool="antismash"
     misc_feature    2772..2787
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: weak, score: 16.03"
                     /tool="antismash"
     misc_feature    2906..2918
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 17.04"
                     /tool="antismash"
     misc_feature    complement(2918..2932)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.51"
                     /tool="antismash"
     gene            2943..3473
                     /gene="ectA"
                     /locus_tag="KV381_RS07100"
                     /old_locus_tag="KV381_07100"
     CDS             2943..3473
                     /EC_number="2.3.1.178"
                     /GO_function="GO:0033816 - diaminobutyrate
                     acetyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0019491 - ectoine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="ectA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015607778.1"
                     /locus_tag="KV381_RS07100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_07100"
                     /product="diaminobutyrate acetyltransferase"
                     /protein_id="WP_078611306.1"
                     /transl_table=11
                     /translation="MTAAPADFARARSEFLSIDTPRVEDGAAIWRIARDSQVLDLNSSY
                     SYLLWCRDFAATSVVARGENGEPIAFVTGYIRPDRPRTLVVWQVAVDQAHRGKGLAATL
                     LDALTARVAADQGLSSVETTITPDNTASDRLFTSYAQRHDVALEQEVLFDGALFPEGTH
                     LPEVLYRIGPFAA"
     gene            3649..4911
                     /gene="ectB"
                     /locus_tag="KV381_RS07105"
                     /old_locus_tag="KV381_07105"
     CDS             3649..4911
                     /EC_number="2.6.1.76"
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /GO_function="GO:0047307 - diaminobutyrate-pyruvate
                     transaminase activity [Evidence IEA]"
                     /GO_process="GO:0019491 - ectoine biosynthetic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_3 (28-363). E-value: 4.7e-72.
                     Score: 234.8. Matches aSDomain:
                     nrpspksdomains_KV381_RS07105_Aminotran_3.1"
                     /codon_start=1
                     /gene="ectB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1013: aminotransferase class-III"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014156968.1"
                     /locus_tag="KV381_RS07105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_07105"
                     /product="diaminobutyrate--2-oxoglutarate transaminase"
                     /protein_id="WP_030088675.1"
                     /sec_met_domain="Aminotran_3 (E-value: 8.3e-77, bitscore:
                     257.3, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTITPPALSVFETLESEVRSYCRGWPAVFDRAQGARLTDEDGHTY
                     LDFFAGAGSLNYGHNNPVLKRALIDYIERDGITHGLDMATTAKRAFLETFQNVILRPRD
                     LPYKVMFPGPTGTNAVESALKLARKVKGRESVVSFTNAFHGMSLGSLAVTGNAFKRAGA
                     GIPLVHGTPMPFDNYFDGTVPDFLWFERLLEDQGSGLNKPAAVIVETVQGEGGINVARA
                     EWLRALKELCERQDMLLIVDDIQMGCGRTGGFFSFEEAGIVPDIVTLSKSISGYGLPMS
                     LCLFKPELDIWEPGEHNGTFRGNNPAFVTAAAALDAYWADGQMEKQTLARGEQVEQTLL
                     AICAEEPTAQFRGRGLVWGMEFEDPARASAVCARAFELGLLLETSGPQSEVVKLLPPLT
                     VTPEELDEGLRTLARCVRETA"
     aSDomain        3733..4737
                     /aSDomain="Aminotran_3"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_KV381_RS07105_Aminotran_3.1"
                     /evalue="4.70E-72"
                     /label="KV381_RS07105_Aminotran_3.1"
                     /locus_tag="KV381_RS07105"
                     /protein_end="363"
                     /protein_start="28"
                     /score="234.8"
                     /tool="antismash"
                     /translation="FDRAQGARLTDEDGHTYLDFFAGAGSLNYGHNNPVLKRALIDYIE
                     RDGITHGLDMATTAKRAFLETFQNVILRPRDLPYKVMFPGPTGTNAVESALKLARKVKG
                     RESVVSFTNAFHGMSLGSLAVTGNAFKRAGAGIPLVHGTPMPFDNYFDGTVPDFLWFER
                     LLEDQGSGLNKPAAVIVETVQGEGGINVARAEWLRALKELCERQDMLLIVDDIQMGCGR
                     TGGFFSFEEAGIVPDIVTLSKSISGYGLPMSLCLFKPELDIWEPGEHNGTFRGNNPAFV
                     TAAAALDAYWADGQMEKQTLARGEQVEQTLLAICAEEPTAQFRGRGLVWGMEFE"
     gene            5001..5399
                     /locus_tag="KV381_RS07110"
                     /old_locus_tag="KV381_07110"
     CDS             5001..5399
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ectoine: ectoine_synt"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006123624.1"
                     /locus_tag="KV381_RS07110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_07110"
                     /product="ectoine synthase"
                     /protein_id="WP_006123624.1"
                     /sec_met_domain="ectoine_synt (E-value: 1.3e-53, bitscore:
                     178.9, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIVRSFSDIENTDRHVKAASGTWESKRIVLAKEKVGFSLHETVLY
                     AGTETSMWYANHIEAVLCTEGEAELTNDETGEKHWITPGTMYLLDGHERHTMRPKTDFR
                     CVCVFNPPVTGREDHDENGVYPLLTEEG"
     gene            5403..6296
                     /gene="thpD"
                     /locus_tag="KV381_RS07115"
                     /old_locus_tag="KV381_07115"
     CDS             5403..6296
                     /EC_number="1.14.11.55"
                     /GO_function="GO:0016706 - 2-oxoglutarate-dependent
                     dioxygenase activity [Evidence IEA]"
                     /codon_start=1
                     /gene="thpD"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PhyH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014156966.1"
                     /locus_tag="KV381_RS07115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_07115"
                     /product="ectoine hydroxylase"
                     /protein_id="WP_030088678.1"
                     /sec_met_domain="PhyH (E-value: 1.1e-38, bitscore: 132.3,
                     seeds: 39, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTEVRADLYPSRGAAEMTTPRQDPVIWSAPGAPGPIVAKDLQSY
                     EHDGFLSIEQLITPDEVAVYQAELDRLISDPAIRADERSIVEKQTQNVRSVFEVHRISE
                     VFAGLVRDERVVGRARQILGSDVYVHQSRINVKPGFGASGFYWHSDFETWHAEDGLPNM
                     RTVSVSIALTENFDTNGGLMIMPGSHKSFLGCAGETPKDNYKKSLQMQDAGTPSDEALT
                     KMADRHGIRLFTGKAGSATWFDCNAMHGSGDNITPYARSNVFIVFNSVENAAEEPFAAP
                     IRRPEFIGARDFTPVK"
     gene            6397..7431
                     /locus_tag="KV381_RS07120"
                     /old_locus_tag="KV381_07120"
     CDS             6397..7431
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010070337.1"
                     /locus_tag="KV381_RS07120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_07120"
                     /product="VOC family protein"
                     /protein_id="WP_218784919.1"
                     /transl_table=11
                     /translation="MSSHVRHITIDCSDAYGLGAFWAQVLDAPLSDEDSPGDPEALVEA
                     PGTAILFVRVEDPKQTKNRVHLDIQPQDRSRDEEVERLLALGATLVGDHRRPNGRGWVT
                     LADPEGNEFCVECSAAERAALTGTRLPVTADDVTSAVRLAVDALAGAPADRWDTPAGSL
                     TWTCWETVEHLSDDLFAYAAQLGPRTPPLDHDVPYRWAPDREGGPHNAVFADRTAGTAG
                     LLATLEASGALLASMARTTPPGVRSYHGYGISDPEGFAAMGVVETLVHTYDLAEGLGLE
                     WSPSPALCDRVLARLFPDAPAGGDRWTVLLWATGRAELPGHPRRTSWRWDGRPPADQTA
                     SSAG"
     gene            complement(7407..8477)
                     /locus_tag="KV381_RS07125"
                     /old_locus_tag="KV381_07125"
     CDS             complement(7407..8477)
                     /GO_function="GO:0010181 - FMN binding [Evidence IEA]"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1217: NADH:flavin oxidoreductase/NADH oxidase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003969934.1"
                     /locus_tag="KV381_RS07125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_07125"
                     /product="alkene reductase"
                     /protein_id="WP_030088682.1"
                     /transl_table=11
                     /translation="MTTAFDPIDLSGTPLANRIALAPMTRSRAGEGGTATELTATYYAQ
                     RASAGLVITEGIQPSAVGQGYPSTPGLHSAEQVASWRTVTDAVHAKGGRIFAQIMHAGR
                     IGHPVLLPDGLVPVSASPVRAEGQVYTHVGPKDFVEPHELTDAEVRATVADFVTAARNA
                     VEAGFDGVELHGANGYLIHQFLAPNTNLRTDAWGGSDEARTRFAVEVVKAVAAEIGPER
                     TALRISPGNPYNDIDEPAPEATYTALVREIEPLGLAYLHILEAVPIRELTLALRKAFSG
                     TVVINVHSDGPTGPGDHTVIDDGIADLISYGALFLANPDLPARLKAGGPFNTPDPSTFF
                     GGDAQGYTDYPALDAV"
     gene            8673..9179
                     /locus_tag="KV381_RS07130"
                     /old_locus_tag="KV381_07130"
     CDS             8673..9179
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1284:
                     transcriptional regulator, MarR family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018957688.1"
                     /locus_tag="KV381_RS07130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_07130"
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="WP_218784920.1"
                     /transl_table=11
                     /translation="MTTGHAAPAEESCTDALPTTAIGGPVSHAVSRVARLHRIAAGKAL
                     KGVELYPGQELLMMHLWDRGAVRQTELIRSLELDPSTVTKMLQRLEQTGHVRRRPDPAD
                     RRAVLVEATDESCALHTAVEAAWGSLEEHTLAGLDPAERAELARLLAKVEENLCRETAD
                     CPDRR"
     gene            complement(9211..10269)
                     /locus_tag="KV381_RS07135"
                     /old_locus_tag="KV381_07135"
     CDS             complement(9211..10269)
                     /NRPS_PKS="Domain: Aminotran_5 (19-347). E-value: 4.3e-23.
                     Score: 73.7. Matches aSDomain:
                     nrpspksdomains_KV381_RS07135_Aminotran_5.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_5"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1139: aminotransferase class V"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012381431.1"
                     /locus_tag="KV381_RS07135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KV381_07135"
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="WP_218784921.1"
                     /sec_met_domain="Aminotran_5 (E-value: 6.2e-16, bitscore:
                     57.0, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTILAPIQAAAVEFAPEVTYLNTSSWGLLPRRTIAAVKALADENA
                     VGRREGAGSFDAVEAARVGFARLAGVHPDRVATGGSVTVHVGLIAASLPAGAEVLCPEG
                     EFASVVSPFALRGDLRVRYAPLADLAGAVRPSTDLVAFSAVQSADGRVADLAAVRAAAA
                     AHGARTLLDATQAAGWFPLDAGAYDYTVTGGFKFLLCPRGTSFLTVTEEAQDTLPPLFA
                     GWVSAGAPWASNYGPLERLAPTARGFDEPPAFLSYHGAEHSLALLAEVGPDALHAHATG
                     LAARLRAGLTGLGREVVPGESAIVSVPGLQGRRDDLMKAGIAVSAPAGNLRISCHLYNT
                     EADVDRVLEFLA"
     aSDomain        complement(9229..10212)
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_KV381_RS07135_Aminotran_5.1"
                     /evalue="4.30E-23"
                     /label="KV381_RS07135_Aminotran_5.1"
                     /locus_tag="KV381_RS07135"
                     /protein_end="347"
                     /protein_start="19"
                     /score="73.7"
                     /tool="antismash"
                     /translation="YLNTSSWGLLPRRTIAAVKALADENAVGRREGAGSFDAVEAARVG
                     FARLAGVHPDRVATGGSVTVHVGLIAASLPAGAEVLCPEGEFASVVSPFALRGDLRVRY
                     APLADLAGAVRPSTDLVAFSAVQSADGRVADLAAVRAAAAAHGARTLLDATQAAGWFPL
                     DAGAYDYTVTGGFKFLLCPRGTSFLTVTEEAQDTLPPLFAGWVSAGAPWASNYGPLERL
                     APTARGFDEPPAFLSYHGAEHSLALLAEVGPDALHAHATGLAARLRAGLTGLGREVVPG
                     ESAIVSVPGLQGRRDDLMKAGIAVSAPAGNLRISCHLYNTEADVDRV"
ORIGIN
        1 tggaaccccc acaagagaca tggagccacc ggcacggtcc aatgggggac atcgcccgtg
       61 ccggcggcct cgactccgtg aatctttacg cactgagggt gaactggcgg atacctggcg
      121 tgagttcacc ccaaaggggg gtttccgcgc gcacattcga atctttcggc acgcgcgttc
      181 cccggtgtca ctcgtttcac ccggctccgg tcgtacggca cccgaacaca ccggacgaca
      241 ccacgacgta cacagaggtg cttcaacgag ccggggccgc ctccgtcact gcccgtcaac
      301 acagcgccgc gccgcccccg acacggcacc gcgccgccgt cagccgatca cgcgcccgtt
      361 cagcacgatg tgccgaggag ccgccagcac ccgcacgtcc gcgcgcggat cctcgtcgta
      421 cacgaccagg tcggccgggg cgccctcctc cagcaccggc cgccccagcc agcgcctggc
      481 tccccacgcg gtggcggaga gggcctccag cggcgggatg cccgccttga ccagctcggc
      541 gacctcgccc gcgaccaggc cgtgcgccag cgagccgccc gcgtcggtgc cgacgtagac
      601 cgggatgccc gcgtcgtacg cggcgcgcac ggtgtcgtag cggcgttcgt acagctgccg
      661 catatgggcg gaccagcggg ggaacttggc ctcgccgccc gccgcgaggt ccgggaaggt
      721 ggcgatgttg accagcgtcg ggacgatcgc gaccccgcgt tcggcgaaga gcgggatggt
      781 ctcctcggtg aggccggtgg catgctcgat gcagtcgatg cccgcctcga ccaggtcggt
      841 gagcgactcc tcggcgaagc agtgcgcggt gacccgggcg ccgagccggt gcgcctcggc
      901 gatggccgcc gccagctcgc cgcgcggcca gcaggcggtc aggtccccgg cgtcgcggtc
      961 gatccagtcc cccaccagct tgacccagcc gtccccgcgc cgggcctccc gggccacgta
     1021 cgcgacgagg tcgccgggct cgatctcatg ggcgtagtta cggatgtagc ggcgggtcct
     1081 ggcgatgtgc cggccggccc tgatgatctt cggcagatcc tcgcggtcgt cgacccaccg
     1141 ggtgtcggag ggcgatccgg cgtcccggat cagcagcgtt ccggcctccc ggtcggcgag
     1201 cgcctgcttc tcggcggtgg ccgcgtcgac cgggccgtgc gcgtccaggc ccacatggca
     1261 gtgcgcgtcg accagaccgg gcagcgccca gccggtgacg gtcaccgcgc ggtccgcgcc
     1321 gggcggccgc tcgtaggtga tccgcccgtc cacggcccac agttcgtccc gcacctcgtc
     1381 cgggccgacg agcacccggc ccttcacccg cagcacccgc tgttcctcct gatcactcat
     1441 aggcggcact gtacgaggcc gccggagggc cgtcggtagg ctgccggtgt ctttccgacc
     1501 gccgcacgca cccgaagaga gccccaccgt gacgcacccc ttcctcgacc tcccgccgct
     1561 caccgccgac cgcttcgcgg cgatcgaacg gtccgtggcc cggctcctcg ccacggagca
     1621 ggacgtcgtc atcacccagg gcgaggcgct gctgccgctg gagggctgca tccgcagcgg
     1681 cgcgcggccc ggctcgaccg cgctgaacgt ggtcaccggc ccctacgggc agaccttcgg
     1741 caactggctg cgggactgcg gcgcgcaggt cgtcgacctc gcggtgccct tccacacggc
     1801 ggtgacggcc ggccaggtcg ccgaggcgct cgccgcgcac ccggagatcg acttcgtctc
     1861 gctggtgcac gcggaggcgg cgaccggcaa caccaatccg gtcgcggaga tcggcgaggt
     1921 ggtccgggcg cacggcgcgc tgttcatgct ggacgcggtc gcctcggtgg gcgccgagcc
     1981 gctgctgccg gacgcctggg gcgtcgacct gtgcgtgatc ggcgcgcaga aggccatggg
     2041 cgggccggcc ggggtctccg cggtgtcggt gagcgcgcgg gcctgggagc ggatggccgc
     2101 caacccggcc gccccgcgcc gctcctacct ctccctcctg gactggaagg agcgctggat
     2161 cgacgggggc cgcaaggcgc tgccgcacgc cccggcgcag ctggagatgc tgggcctgga
     2221 ggcctgtgtg gcgcggatcg aggacacggg cctggacacg gtgatggccc gccacgcctc
     2281 ggcggccgcg gcgacccggg cgggtgcggt ggcactgggc ggcggtctgg agccgtacgt
     2341 ccacgccgcg cgggacgccg ctccggtggc cacgacgctg cgcgccccgg cggggaccga
     2401 cgccgccgcg ctggtcgcgc acgcgctggc ggccgatccc tcgctcccgc tcgtcgcggg
     2461 cggcggggcg ctgtccaagg agatgatccg ggtcaatcac tacggggcgg atgcgacgcg
     2521 ggacgcggtg ctgtcctcgc tcgcggctct ggggtcggcg ctgaccgatg cgggcctgcg
     2581 ggtcgatatc gatgctgccc gggccgccgt ttcggaaacc tggccgggcc gctgatattc
     2641 ataatgcggg gagctgcttt atcgaaagca gctccccgca ttcttctgcc cgctttcccg
     2701 gtacctaaac gcggaagttt ttcgggcatc gaacttcgtg attcggacac gtctcaggag
     2761 agttacaacc ctgtgaccga ctccacatcg gcggcgttat gcccgaaaaa ttcgggacaa
     2821 agagcctgaa aaaccacccg gatcatggcg gatctcgcgc acgcctgata acacacgaag
     2881 gcgcttcacc caacccttca cgtcgatgca atttcgaaat ttgctgggta aattcaattc
     2941 ccatgaccgc cgcaccagca gattttgccc gtgcccgaag cgaattcctc agtatcgaca
     3001 ccccacgagt ggaggacgga gccgcgatct ggcgcatcgc ccgcgactcc caggtcctgg
     3061 acctgaactc ctcgtacagc tacctgctgt ggtgtcgtga cttcgccgcg acctccgtcg
     3121 tcgcccgtgg cgagaacggc gagcccatcg ccttcgtgac gggctacatc cggcccgacc
     3181 gcccccggac cctcgtcgtc tggcaggtgg ccgtggacca ggcccaccgc ggcaaggggc
     3241 tggccgccac tctgctggac gcgctgaccg cccgggtcgc cgccgaccag ggcctgtcgt
     3301 ccgtggagac gacgatcacc ccggacaaca ccgcatccga ccggctgttc acgtcctacg
     3361 cccagcgcca cgacgtcgcg ctggagcagg aggtgctctt cgacggcgcg ctgttccccg
     3421 aagggacgca tctgcccgag gtgctctacc ggataggccc gttcgccgcc tgaccggcct
     3481 gttcgccggc cgcacccgcc cggccgccac cccggcgtac ccgacccgta cgcccggcct
     3541 cccagacttt tcgcgccggc cgaccacccg gcgcggtccc ggccgcctcc gtgcggcggg
     3601 gagcactcga ccaccgcccg tcacaccccc tcacgcagga gatccgctgt gaccatcacc
     3661 ccgcccgcac tgagcgtctt cgagaccctt gagtccgagg tccgcagcta ctgccgcggc
     3721 tggcccgccg tgttcgaccg cgcccagggc gcccggctga ccgacgagga cggccacacc
     3781 tacctggact tcttcgccgg ggccggttcg ctgaactacg gccacaacaa cccggtgctg
     3841 aaacgagcgc tgatcgacta catcgagcgc gacggcatca cccacggtct cgacatggcg
     3901 accaccgcca agcgcgcgtt cctggagacg ttccagaacg tgatcctgcg gccgcgcgac
     3961 ctgccgtaca aggtgatgtt ccccggcccg accggcacca acgccgtcga gtcggcgctg
     4021 aagctggccc gtaaggtcaa gggccgcgag tccgtcgtct cgttcaccaa cgccttccac
     4081 ggcatgtcgc tgggctcgct ggccgtcacc ggcaacgcgt tcaagcgggc cggtgccggg
     4141 atcccgctgg tgcacggcac cccgatgccg ttcgacaact acttcgacgg cacggtcccc
     4201 gacttcctgt ggttcgagcg actgctggag gaccagggct ccgggctgaa caagcccgcc
     4261 gccgtgatcg tggagacggt ccagggcgag ggcggcatca acgtggcccg cgccgagtgg
     4321 ctgcgcgcgc tcaaggagct gtgcgagcgc caggacatgc tgctgatcgt cgacgacatc
     4381 cagatgggct gcggccgtac cggcggcttc ttctccttcg aggaggccgg catcgtcccg
     4441 gacatcgtca cgctgtcgaa gtcgatcagc ggctacggac tgccgatgtc gctctgcctg
     4501 ttcaagccgg agctggacat ctgggagccg ggcgagcaca acggcacctt ccgcggcaac
     4561 aacccggcct tcgtcacggc cgccgccgcg ctggacgcct actgggcgga cggccagatg
     4621 gagaagcaga ccctggcccg cggcgagcag gtcgagcaga cgctgctggc catctgcgcc
     4681 gaggagccga ccgcgcagtt ccgcggccgg ggcctggtgt ggggcatgga gttcgaggac
     4741 ccggcgcgcg cctcggcggt ctgcgcccgc gccttcgagc tggggctcct gctggagacc
     4801 tcgggcccgc agagcgaggt cgtcaagctg ctgccgccgc tgaccgtcac ccccgaggaa
     4861 ctggacgagg gcctgcgcac gctggcccgc tgcgtccgcg agacagcctg acccggaacg
     4921 gccggggcag gcgcagaaga agaggtcccg ggccgcgagg cccggggccc gtgcagagaa
     4981 gagaaaggca accgctcacc gtgatcgtcc gatcgttcag tgacatcgag aacaccgacc
     5041 ggcatgtgaa ggccgcgtcc ggcacctggg agagcaagcg catcgtgctc gccaaggaga
     5101 aggtgggctt ctcgctccac gagaccgtgc tgtacgcggg cacggagacc tccatgtggt
     5161 acgcgaacca catcgaggcg gtgctgtgca ccgagggcga ggccgagctc accaacgacg
     5221 agaccggcga gaagcactgg atcacgcccg gcacgatgta tctgctggac ggacatgagc
     5281 ggcacaccat gcggcccaag accgacttcc gctgcgtgtg cgtcttcaat ccccccgtca
     5341 ccggacggga ggaccatgac gagaacggtg tctacccact gctgaccgag gagggctgaa
     5401 ccatgaccac cgaagtacgc gccgatctgt acccctcgcg cggcgccgcc gagatgacca
     5461 ctccccgcca ggacccggtc atctggtccg cgccgggcgc accgggcccg atcgtcgcca
     5521 aggacctcca gagctacgag cacgacggct tcctcagcat cgagcagctg atcacgccgg
     5581 acgaggtcgc cgtctaccag gcggagctgg accggctgat ctccgacccg gcgatccgcg
     5641 ccgacgagcg ctccatcgtc gagaagcaga cgcagaacgt gcggtccgtc ttcgaggtcc
     5701 accggatcag tgaggtcttc gccgggctgg tccgtgacga gcgggtggtg ggccgggccc
     5761 gccagatcct cggctcggac gtgtacgtcc accagtcccg gatcaatgtg aagccgggct
     5821 tcggggcctc gggcttctac tggcactcgg acttcgagac ctggcacgcg gaggacggtc
     5881 tgccgaacat gcggacggtg tccgtgtcga tcgcgctgac cgagaacttc gacaccaacg
     5941 gcgggctgat gatcatgccc ggttcgcaca agtcgttcct cggctgtgcg ggcgagacgc
     6001 cgaaggacaa ctacaagaag tcgctccaga tgcaggacgc cggcaccccg tccgacgagg
     6061 cgctgacgaa gatggccgac cgccacggca tcaggctctt cacgggcaag gccggttcgg
     6121 cgacctggtt cgactgcaac gccatgcacg gctcgggcga caacatcacc ccgtacgcgc
     6181 gcagcaatgt cttcatcgtc ttcaacagcg tggagaacgc ggccgaggag cccttcgcgg
     6241 ctccgatccg ccgccccgag ttcatcgggg cgcgggactt cactccggtg aagtagccgt
     6301 acgcaccagg gagtcggggc cgggacggta cgccgtcccg gccctgcgcg cgtaactcgc
     6361 tggaccgggg ccgggtcagc ggacagggtg tccgccatga gttcccacgt acgccacatc
     6421 acgatcgact gttccgacgc ctacggactc ggcgccttct gggcccaggt gctcgacgcc
     6481 ccgctctccg acgaggactc ccccggtgat ccggaggcgc tggtcgaggc gcccggcacg
     6541 gcgatcctct tcgtccgggt ggaggatccg aaacagacca agaaccgggt ccatctggac
     6601 atccagccgc aggaccgctc ccgggacgag gaggtcgagc ggctgctcgc gctcggggcc
     6661 acgctggtgg gcgaccaccg ccgaccgaac gggcggggct gggtgacgct cgccgatccc
     6721 gagggcaacg agttctgtgt ggagtgctcc gccgccgagc gggcggcgct gaccggcacc
     6781 cggctgccgg tgacggccga cgatgtgacc tcggcggtgc ggctcgcggt ggacgcgctg
     6841 gccggtgccc cggcggaccg ctgggacacg cccgccggaa gcctcacgtg gacctgctgg
     6901 gagacggtgg agcacctgag cgacgatctg ttcgcgtacg cggcgcagtt gggccctcgt
     6961 acgcctccgc tggaccacga tgtgccctac cggtgggcgc cggaccggga gggcgggccg
     7021 cacaacgcgg tcttcgccga ccggacggcg gggaccgccg ggctgctggc cacgctggag
     7081 gcgagcgggg cgctgctggc ctcgatggcg cggacgacgc cgcccggggt gcgctcgtac
     7141 cacgggtacg ggatctccga cccggagggc ttcgccgcga tgggcgtggt ggagaccctg
     7201 gtgcacacgt acgacctcgc cgagggcctg gggctggagt ggtcgccgtc cccggcgctc
     7261 tgcgaccggg tgctggcccg gctcttcccc gacgccccgg cgggcggcga ccggtggacc
     7321 gtcctgctgt gggccaccgg ccgcgccgag ctgccgggcc acccgcgccg cacctcgtgg
     7381 cggtgggacg ggcggccccc ggcggatcag acggcgtcga gcgccgggta gtcggtgtag
     7441 ccctgggcgt cgccgccgaa gaaggtcgac gggtcggggg tgttgaacgg gccgcccgcc
     7501 ttcagccggg cgggcaggtc cgggttggcg aggaagagcg ccccgtagga gatcaggtcg
     7561 gcgatgccgt cgtcgatcac cgtgtggtcg ccgggtccgg tggggccgtc ggagtgcacg
     7621 ttgatgacga cggtcccgga gaaggccttg cgcagggcga gggtcagctc gcggatcggg
     7681 acggcctcca ggatgtgcag ataggcgagg ccgagcggct cgatctcccg gaccagcgcg
     7741 gtgtacgtgg cctccggcgc gggctcgtcg atgtcgttgt acgggttgcc gggcgagatg
     7801 cgcagtgcgg tgcgctccgg gccgatctcg gcggcgacgg ccttgacgac ctcgacggcg
     7861 aagcgggtgc gggcctcgtc ggagccgccc caggcgtcgg tgcgcaggtt ggtgttgggg
     7921 gcgaggaact ggtggatgag gtagccgttg gcgccgtgca gctcgacccc gtcgaatccg
     7981 gcctccacgg cgttgcgggc ggcagtgacg aagtcggcga cggtcgcgcg gacctcggcg
     8041 tcggtcagct cgtgcggctc gacgaagtcc ttcgggccga cgtgggtgta gacctgcccc
     8101 tcggccctga ccggggaggc gctgacgggg acgaggccgt cggggagcag gaccgggtgg
     8161 ccgatgcggc ccgcgtgcat gatctgggcg aagatcctgc cgcccttcgc gtgcaccgcg
     8221 tcggtgaccg tacgccacga ggcgacctgc tcggcgctgt gcagcccggg cgtggagggg
     8281 tagccctggc ccacggcgga cggctggatg ccctcggtga tcaccaggcc ggccgaggcg
     8341 cgctgggcgt agtaggtggc ggtgagctcg gtggcggtgc cgccctcacc ggcccggctg
     8401 cgggtcatcg gggccagggc gatgcggttg gccagcgggg tgccggacag gtcgatcggg
     8461 tcgaaagcgg tggtcatgaa ggctcccaag aaagtatgtg gtcggccaag catcggcgcc
     8521 gacggccacc atagcccatt cattggccga ccaaggtaaa gtcgtgggaa accgtcgggc
     8581 gttcagtccg gcatccggtc gggcatcatc ggaagccgcc accgaaagcc cccgccagag
     8641 cccgtccggc ccgaggaccc caggagcccg ccatgaccac cggccacgcc gcccccgcgg
     8701 aagagtcctg taccgacgcg ctgcccacga cggcgatcgg cgggccggtg agccacgccg
     8761 tctcccgggt ggcccggctg caccggatcg cggcgggcaa agcgctcaag ggggtggagc
     8821 tctacccggg gcaggaattg ctgatgatgc acctgtggga ccggggggcg gtccgtcaga
     8881 cggagctgat caggtcactg gagctggacc cgtccacggt cacgaagatg ctccagcgac
     8941 tggagcagac cgggcatgtg cgccgccgcc ccgacccggc cgaccggcgg gccgtactgg
     9001 tcgaggcgac ggacgagagc tgcgcgctgc acaccgcggt cgaggccgcc tggggcagcc
     9061 tggaggagca cacgctcgcg ggcctggacc cggccgagcg cgcggagctg gcgcggctgc
     9121 tggcgaaggt cgaggagaac ctctgccggg agaccgcgga ctgccccgac cggcgctgag
     9181 ccgtacggcc cccggacgca cgcggagcgg tcaggccagg aactccagca cccggtccac
     9241 atcggcctcg gtgttgtaga ggtggcagga gatccgcaga ttcccggccg gggccgagac
     9301 ggcgatcccg gccttcatca gatcgtcccg acggccctgc agccccggta cggagacgat
     9361 cgccgactcc ccgggcacca cctcgcgccc gagcccggtc agcccggcgc gcagccgcgc
     9421 cgcgagcccg gtggcgtgcg cgtgcagggc gtcggggccg acctccgcga gcagggcgag
     9481 ggagtgctcc gccccgtggt acgagaggaa ggcaggcggc tcgtcgaagc cgcgggcggt
     9541 cggggcgagg cgctccagcg ggccgtagtt gctcgcccag ggcgcaccgg cggagaccca
     9601 gccggcgaag agcggcggca gggtgtcctg cgcctcctcg gtgaccgtca ggaacgacgt
     9661 accgcgcggg cagagcagga acttgaagcc accggtgacg gtgtagtcgt acgccccggc
     9721 gtccagcggg aaccagcccg ccgcctgggt ggcgtccagc agggtccggg ccccgtgcgc
     9781 cgcggcggcc gcgcggacgg cggcgaggtc ggcgacccgg ccgtcggccg actgcaccgc
     9841 ggagaaggcg accaggtcgg tcgagggccg tacggccccg gcgaggtccg cgagcggcgc
     9901 gtaccgtacg cgcagatcgc cgcggagcgc gaacgggctg accacggagg cgaactcgcc
     9961 ctcgggacag aggacttcgg caccggccgg cagcgaagcg gcgatcaggc cgacgtgcac
    10021 ggtgacggaa ccgccggtgg cgacccggtc ggggtggacc ccggcgagcc gggcgaaccc
    10081 gacccgggcg gcctcgaccg cgtcgaagct gcccgccccc tcccgccggc cgacggcgtt
    10141 ctcgtcggcc agggccttga cggcggcgat cgtccggcgg ggcagcagac cccagctgga
    10201 ggtgttgagg taggtgacct cgggcgcgaa ttcgacggct gcggcttgga tgggcgcgag
    10261 gatcgtcata cgtccaccct gaagccccct caacccaaag tcaattactg agagttaagg
    10321 ggtgcaccca aggatcgctt atgtatcact ggtgaaccgc gtccgccgga gctcagctcc
    10381 ccgggacctc gcaggcccc
//
