LOCUS       NZ_JAHTMR010000013     22172 bp    DNA     linear   CON 21-AUG-2024
DEFINITION  Pseudomonas sp. PD9R Contig_13_consensus_sequence, whole genome
            shotgun sequence.
ACCESSION   NZ_JAHTMR010000013
VERSION     NZ_JAHTMR010000013.1
KEYWORDS    WGS; RefSeq.
SOURCE      Pseudomonas sp. PD9R
  ORGANISM  Pseudomonas sp. PD9R
            Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales;
            Pseudomonadaceae; Pseudomonas.
REFERENCE   1  (bases 1 to 214502)
  AUTHORS   Tournay,R., Firrincieli,A., Parikh,S. and Dominic,S.
  TITLE     Isolation and characterization of arsenic-tolerant endophytes and
            the potential of endophytic biofilms in arsenic tolerance
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 214502)
  AUTHORS   Tournay,R., Firrincieli,A. and Doty,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUL-2021) School of Environmental and Forest Sciences,
            University of Washington, 4000 15th Ave NE, Seattle, WA 98195, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 23-JAN-2020
            Assembly Method                   :: Geneious Prime v. 2020.0.3
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 158.0x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_019200975.1-RS_2024_08_21
            Annotation Date                   :: 08/21/2024 05:49:47
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,297
            CDSs (total)                      :: 6,222
            Genes (coding)                    :: 6,093
            CDSs (with protein)               :: 6,093
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 61
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 2 of 129
            Pseudo Genes (frameshifted)       :: 24 of 129
            Pseudo Genes (incomplete)         :: 110 of 129
            Pseudo Genes (internal stop)      :: 10 of 129
            Pseudo Genes (multiple problems)  :: 15 of 129
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 02:28:33
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 58754
            Orig. end                         :: 80926
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JAHTMR010000013.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22172
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="redox-cofactor"
                     /region_number="1"
                     /rules="(cds(PF04055 and (TIGR04085 or SPASM)) and
                     (TIGR02111 or TIGR03966) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]))"
                     /tool="antismash"
     cand_cluster    1..22172
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(cds(PF04055 and (TIGR04085 or SPASM))
                     and (TIGR02111 or TIGR03966) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]))"
                     /kind="single"
                     /product="redox-cofactor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22172
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12172](+)"
                     /cutoff="20000"
                     /detection_rule="(cds(PF04055 and (TIGR04085 or SPASM)) and
                     (TIGR02111 or TIGR03966) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]))"
                     /neighbourhood="10000"
                     /product="redox-cofactor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12172
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cds(PF04055 and (TIGR04085 or SPASM)) and
                     (TIGR02111 or TIGR03966) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]))"
                     /neighbourhood="10000"
                     /product="redox-cofactor"
                     /protocluster_number="1"
     gene            complement(465..2819)
                     /locus_tag="KUF73_RS22755"
                     /old_locus_tag="KUF73_22760"
     CDS             complement(465..2819)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016704067.1"
                     /locus_tag="KUF73_RS22755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KUF73_22760"
                     /product="glucose/quinate/shikimate family membrane-bound
                     PQQ-dependent dehydrogenase"
                     /protein_id="WP_218440265.1"
                     /transl_table=11
                     /translation="MNNSGAAAGSKWLLVGLGVLIALIGLGLAGGGGYLIALGGSWYFL
                     LMGLAMLVSGLMIARRKPAGAWLYGLALIMTAIWAVWDAGFEYWPLVSRVLTFAVIGLV
                     VVLIYPTLVRASGASAGRGAYGVAGILGVGIVATMAYMFVPTHVVKASSEPTVIPVAPG
                     TEQKDWAHWGNTTAGNRFAALDQINKGNIDKLQVAWTFRTGDIPQSTGAGAEDQNTPLQ
                     IGDTVYTCTAYGKVFALDADTGAQRWKFDPQGSAPNWQRCRGLGYSETPASSDNQPTAC
                     TKRLFLPTGDARLIAINAETGKPCEEFGNKGTVDLKTDMGEVKPGYYQQTSTPLVAGNV
                     VIVGGRVADNYSTGEPPGVVRAYDVRSGELVWAWDPGNPNTTKRPPAGETYTRGTPNVW
                     SAMSYDAKLGLVYLPTGNATPDFFGGQRTEFDDKWNSSIVAIDVKTGQVRWHFQTTHHD
                     LWDFDLPAQPLLYDVPDDKGGTQPALAQVTKQGEIFLLNRETGVPIARVEERPVPQGHV
                     PGERYSPTQPFSVDMPSIGNKTLTESDMWGATPFDQLMCRIQFKGMRHEGVYTPPGMDR
                     ALQFPGSLGGMNWGSVSVDPNTNYMFVNDMRLGLANYMIPRDKIGAGASGIEMGVVPQE
                     GTPFGAMRERFLSAAGIPCQKPPFGTMSAIDLKTHKLMWQVPVGTVQDTGPLGIRMHLP
                     IPIGMPTLGASLATQSGLLFFAGTQDFYLRAFDTGNGNEIWKARLPVGSQSGPMTYVSP
                     KTGKQYILLTVGGARQSTDRGDYVIAYALPE"
     gene            3005..3466
                     /locus_tag="KUF73_RS22760"
                     /old_locus_tag="KUF73_22765"
     CDS             3005..3466
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1120: AsnC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020798842.1"
                     /locus_tag="KUF73_RS22760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KUF73_22765"
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="WP_031319160.1"
                     /transl_table=11
                     /translation="MPDTRPPVLDEIDRQLIAALQLNARESVAMLARQLGIARTTVTSR
                     LARLEKAKVITGYGVRLGQRVVDGGLQAYVGITVQPRSGKEVLRRLSAMAQVQQLCAVS
                     GEFDYVAWLRTDSPEQLDQLLDQIGSVDGVEKTTTSIILSSKIDRGQPV"
     gene            3688..5370
                     /locus_tag="KUF73_RS22765"
                     /old_locus_tag="KUF73_22770"
     CDS             3688..5370
                     /EC_number="1.-.-.-"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008147187.1"
                     /locus_tag="KUF73_RS22765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KUF73_22770"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_218440266.1"
                     /transl_table=11
                     /translation="MNKNNRHPADGKKPVTIFGPDFPFAFDDWIEHPAGLGSIPEHNHG
                     AEVAIVGGGIAGLVAAYELMKLGLKPVVYEASKMGGRLRSQAFNGAEGIIAELGGMRFP
                     VSSTAFYHYVDKLGLQTKPFPNPLTPASGSTVIDLEGQTHYAQKLSDLPALFQEVADAW
                     ADALEAGSQFSDIQQAIRDRDVPRLKELWNTLVPLWDDRTFYDFVATSKAFAKLSFHHR
                     EVFGQVGFGTGGWDSDFPNSMLEIFRVVMTNCDDHQHLVVGGVEQVPLGIWRHVPERCA
                     HWPAGTSLSSLHNGAPRTGVKKIAHAEGGRFAVTDNWGDTREYAAVLTTCQSWLLTTQI
                     ECDESLFSQKMWMALDRTRYMQSSKTFVMVDRPFWKDKDPETGRDLMSMTLTDRLTRGT
                     YLFDNGDDKPGVICLSYSWMSDALKMLPQPVEKRVKLALDALKKIYPKVDIAARIIGDP
                     ITVSWEADPHFLGAFKGALPGHYRYNQRMYAHFMQDDMPAEQRGIFIAGDDVSWTPAWV
                     EGAVQTSLNAVWGIMKHFGGATHAENPGPGDVFNEIGPIALPE"
     gene            5383..6177
                     /locus_tag="KUF73_RS22770"
                     /old_locus_tag="KUF73_22775"
     CDS             5383..6177
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1294: Nitrilase/cyanide hydratase and apolipoprotein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007947815.1"
                     /locus_tag="KUF73_RS22770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KUF73_22775"
                     /product="carbon-nitrogen hydrolase family protein"
                     /protein_id="WP_218440267.1"
                     /transl_table=11
                     /translation="MRVALYQCPPLPLDVAGNLQRLQQLAQEAKGADLLVLPEMFLTGY
                     NIGVDAVSVLAEVHNGESAQQIARIAKSAGIAILYGYPERTEDGQIYNAAQLIDANGER
                     LCNYRKTHLFGDLDRSMFSPGTNDFPVVELNGWKLGLLICYDLEFPENARRLALDGVEL
                     ILVPTANMIPFDFIADVTVRSRAFENQCYVAYANYCGHEGDIHYCGQSSIAAPDGSRIA
                     QAGLDEALIVGELDRQLMVDSRAANRYLLDRRPELYGDLNKR"
     gene            6220..8649
                     /gene="pqqF"
                     /locus_tag="KUF73_RS22775"
                     /old_locus_tag="KUF73_22780"
     CDS             6220..8649
                     /EC_number="3.4.24.-"
                     /GO_function="GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /GO_process="GO:0018189 - pyrroloquinoline quinone
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="pqqF"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M16"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M16_C"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007936525.1"
                     /locus_tag="KUF73_RS22775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KUF73_22780"
                     /product="pyrroloquinoline quinone biosynthesis protein
                     PqqF"
                     /protein_id="WP_218440268.1"
                     /sec_met_domain="Peptidase_M16 (E-value: 6.3e-37, bitscore:
                     120.4, seeds: 24, tool: rule-based-clusters)"
                     /sec_met_domain="Peptidase_M16_C (E-value: 1.2e-08,
                     bitscore: 28.7, seeds: 139, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSALNHLRPHTETLANGLRVTLRHAPELKRCAAALRVAVGSHDVP
                     LAWPGLAHFLEHLLFLGTERFPAGQGLMAYVQRHGGQVNARTSERTTDYFFELPPLAFA
                     GGLERLSDMLAHPYMNLEDQQREREVLQAEFIAWSQDATAQQQLTLFDGVAETHPLRGF
                     HAGNRDSLPVPQPEFQQALLDFFQQYYQTGQMTLSLVGPQNLEELKALAQAFAEAIPEG
                     NSIAQQAATPLMGDSDKSYQQVNERRLDLLFALEALPDSSPEALEFLCHWLNAAKPEGL
                     LAELQNRGWAEKLKAAPLYQFAGQALLHIEFTRDTNTQPTAIRDLLMDWLGFFAQQDWS
                     GLRDEYAALLQRQQQVSSALQLARLDSERHEAGLSEHGVTALQQILQQLRAVDNFTGQW
                     QLPTPNPFLRAESAAPNAGLIRGQTSAHRGLRTFAQDRSRSRRERSPMQFSQALPDNSA
                     EGAVYVRWRLDAAPGNHLQSRLAKHLQPLCEEAHQAGVDVSFSAAGNEWRLKMTGLQEP
                     MPTVLEHVLKELANTDADFLCDESTAVALMPIRQLLKALPDHCLEQTAVSDDAKQLWSS
                     ARWDGLAIGLSAQTQAAMGLALSRIPGTPDNQLTLPPSIHTQHLWHTVATGSSEHALLL
                     FCPTPSQEIADEAAWRLLAHVCQTPFYQRLRVELQLGYAVFSDLRQIHGQTGLLFGVQS
                     PSVAPLDLLLHIEQFLSGLPDMIRNLDDISFIALRQTLANQFESTAMPNAEAAELLWQG
                     KLAGRSSDYLKQLPQVILQIDQAALVGAAQRLNQAEGGWRCLASAACPGSPWQVAK"
     gene            8805..8879
                     /gene="pqqA"
                     /locus_tag="KUF73_RS22780"
                     /old_locus_tag="KUF73_22785"
     CDS             8805..8879
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_process="GO:0018189 - pyrroloquinoline quinone
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="pqqA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003444522.1"
                     /locus_tag="KUF73_RS22780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KUF73_22785"
                     /product="pyrroloquinoline quinone precursor peptide PqqA"
                     /protein_id="WP_003444522.1"
                     /transl_table=11
                     /translation="MAWTKPAYTDLRIGFEVTMYFASR"
     gene            8961..9872
                     /gene="pqqB"
                     /locus_tag="KUF73_RS22785"
                     /old_locus_tag="KUF73_22790"
     CDS             8961..9872
                     /GO_process="GO:0018189 - pyrroloquinoline quinone
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="pqqB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017701795.1"
                     /locus_tag="KUF73_RS22785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KUF73_22790"
                     /product="pyrroloquinoline quinone biosynthesis protein
                     PqqB"
                     /protein_id="WP_218440269.1"
                     /transl_table=11
                     /translation="MFVQILGSAAGGGFPQWNCNCVNCAGFRDGSLNARARTQSSIAIS
                     DDGVNWVLCNTSPDIRAQLQSFAPMQPGRALRDTGISAIILMDSQIDHTTGLLMLREGC
                     PHQVWCTDMVHEDLSTGFPLFTMLNHWNGGLNWNRIELDQSFSIPACPNLRFTPLPLRS
                     AAPPYSPHRFDPHPGDNIGLIVEDLGTGGKLFYAPGLGKVDAPLLEIMAGSDCLLVDGT
                     LWDDDEMQRRGVGTRSGREMGHLAQNGPGGMLEVLGQLPKQRKVLIHINNTNPILDEDS
                     PERAELDRRDVEVAYDGMSIVL"
     gene            10001..10753
                     /gene="pqqC"
                     /locus_tag="KUF73_RS22790"
                     /old_locus_tag="KUF73_22795"
     CDS             10001..10753
                     /EC_number="1.3.3.11"
                     /GO_process="GO:0018189 - pyrroloquinoline quinone
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="pqqC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: TIGR02111"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007926092.1"
                     /locus_tag="KUF73_RS22790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KUF73_22795"
                     /product="pyrroloquinoline-quinone synthase PqqC"
                     /protein_id="WP_218440270.1"
                     /sec_met_domain="TIGR02111 (E-value: 1.5e-129, bitscore:
                     423.9, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDTPMSPDEFEAALRAKGAYYHIYHPYHVAMYEGRATREQIQGW
                     VANRFYYQVNIPLKDAAILANCPDREIRREWIQRLLDHDGAPGEDGGIEAWLRLGQAVG
                     LDPDQLRSQELVLPGVRFAVDAYVNFARRASWQEAASSSLTELFAPQIHQSRLDSWPQH
                     YPWIDPAGYEYFRTRLGQARRDVEHGLAITLQHYTTREGQERMLEILQFKLDILWSMLD
                     AMSMAYELNRPPYHSVTEQRVWHKGITL"
     gene            10750..11025
                     /gene="pqqD"
                     /locus_tag="KUF73_RS22795"
                     /old_locus_tag="KUF73_22800"
     CDS             10750..11025
                     /GO_function="GO:0048038 - quinone binding [Evidence IEA]"
                     /GO_process="GO:0018189 - pyrroloquinoline quinone
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="pqqD"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004419445.1"
                     /locus_tag="KUF73_RS22795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KUF73_22800"
                     /product="pyrroloquinoline quinone biosynthesis peptide
                     chaperone PqqD"
                     /protein_id="WP_218440271.1"
                     /sec_met_domain="PqqD_RRE (E-value: 2.1e-35, bitscore:
                     113.9, seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 1.6e-15, bitscore: 50.7,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSFDRSKTPTWRPGYRFQYEPAQKGHVLLYPEGMIKLNESAALIG
                     GLIDGERDVAAIIVELDQQFPGVPELGDDIEQFMEVARAQHWIELA"
     aSDomain        10753..11019
                     /aSDomain="PqqD_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing protein in a pyrroloquinoline
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_KUF73_RS22795_PqqD_RRE.1"
                     /evalue="3.20E-36"
                     /identifier="RREFam006.1"
                     /label="KUF73_RS22795"
                     /locus_tag="KUF73_RS22795"
                     /protein_end="90"
                     /protein_start="1"
                     /score="113.9"
                     /tool="antismash"
                     /translation="SFDRSKTPTWRPGYRFQYEPAQKGHVLLYPEGMIKLNESAALIGG
                     LIDGERDVAAIIVELDQQFPGVPELGDDIEQFMEVARAQHWIEL"
     gene            10997..12172
                     /gene="pqqE"
                     /locus_tag="KUF73_RS22800"
                     /old_locus_tag="KUF73_22805"
     CDS             10997..12172
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /GO_process="GO:0018149 - peptide cross-linking [Evidence
                     IEA]"
                     /GO_process="GO:0018189 - pyrroloquinoline quinone
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="pqqE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: TIGR04085"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: PF04055"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: SPASM"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PTHR43273"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) QueE"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007936504.1"
                     /locus_tag="KUF73_RS22800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KUF73_22805"
                     /product="pyrroloquinoline quinone biosynthesis protein
                     PqqE"
                     /protein_id="WP_256345672.1"
                     /sec_met_domain="PTHR43273 (E-value: 8.2e-32, bitscore:
                     104.1, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 2.7e-26, bitscore: 86.5,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 2.8e-09, bitscore: 30.9,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="QueE (E-value: 6.3e-07, bitscore: 22.6,
                     seeds: 32, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 8.8e-11, bitscore: 35.8,
                     seeds: 166, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 4.5e-09, bitscore:
                     30.2, seeds: 281, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLSTGSNLPDSASDKLPPKPEIGLPLWLLAELTYRCPLQCPYCSN
                     PLDFAEQGKELSTEQWLKVFREAREMGAAQLGFSGGEPLVRQDLAELIAEARKLGFYTN
                     LITSGIGLTEQKISDFKKAGLDHIQISFQASDEQVNNLLAGSKKAFAQKLEMARAVKAH
                     GYPMVLNFVTHRHNIDKIDRIIELCIALEADFVELATCQFYGWAQLNRVGLLPTREQLV
                     RAERITNEYRAKLEAEGHPCKLIFVTPDYYEERPKACMNGWGSIFLTVTPDGTALPCHG
                     ARQMPVQFPNVRDHSMQHIWYDSFGFNRFRGHDWMPEPCRSCDEKEKDFGGCRCQAFML
                     TGDASNADPVCSKSQHHGVILKAREEAEHATQTIEQLAFRNERNSRLIAKS"
     gene            12138..13961
                     /locus_tag="KUF73_RS22805"
                     /old_locus_tag="KUF73_22810"
     CDS             12138..13961
                     /EC_number="3.4.-.-"
                     /GO_function="GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S9"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007904207.1"
                     /locus_tag="KUF73_RS22805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KUF73_22810"
                     /product="S9 family peptidase"
                     /protein_id="WP_218440272.1"
                     /sec_met_domain="Peptidase_S9 (E-value: 6e-48, bitscore:
                     156.6, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNETHASSPKAEPFSAANAVAAGIDFAELQLGVHGLFWNEYRPED
                     AACRIWHWRDGVAKCLTPSGFSVRSRVYEYGGGAFCLTDDGVVFVNEADQQLYRQSLHG
                     EPAVLTSGVCRYGDLQFADGQVLAVEEHRDRHRLVAIDLADGSHHLLAEGADFYAAPTL
                     SPDARRLAWIEWSRPDQPWTATRLMVAERLDDGGFAPPRCVAGDNAQESLQQPRFDDSG
                     RLFCLTDRGGFWQPWMESANGLSSLPSAAADHGPAPWQLGGCTWLPLGETRYLASWSEG
                     GFGRLGLCGATCEDFTGDYSRFRHLALDEHFIYCIAASPISSSAVIAIDRHTREVKKLA
                     GGITPLPTQQISVPQTLRYPSGSGEAHGFFYPAMTSDAKPPLVVFIHGGPTSACYPMLD
                     PRIQYWTQRGFAVADLNYRGSSGYGRAYRQALHLSWGDVDVEDACAVVSHLAERGLING
                     DKAFIRGGSAGGYTTLCALAFHKVFRAGASLYGVSDPVALGRATHKFEGDYLDWLIGDP
                     AQDAERYAARTPLLHASNISVPVIFFQGELDAVVVPQQTRDMVSALQSNGILVEAHYYA
                     DERHGFRKAVNQAHALEQEWLFYRRVMEIAG"
     gene            complement(14068..14226)
                     /locus_tag="KUF73_RS22810"
                     /old_locus_tag="KUF73_22815"
     CDS             complement(14068..14226)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_249258.1"
                     /locus_tag="KUF73_RS22810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KUF73_22815"
                     /product="YqaE/Pmp3 family membrane protein"
                     /protein_id="WP_003228885.1"
                     /transl_table=11
                     /translation="MDFIRIIIAILLPPLGVFLQVGFGGAFWLNILLTLCGYIPGIVHA
                     VYIIAKR"
     misc_feature    complement(14211..14225)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 19.14"
                     /tool="antismash"
     gene            complement(14434..15717)
                     /locus_tag="KUF73_RS22815"
                     /old_locus_tag="KUF73_22820"
     CDS             complement(14434..15717)
                     /NRPS_PKS="Domain: Aminotran_3 (45-360). E-value: 3.6e-82.
                     Score: 268.0. Matches aSDomain:
                     nrpspksdomains_KUF73_RS22815_Aminotran_3.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1013: aminotransferase class-III"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020796022.1"
                     /locus_tag="KUF73_RS22815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KUF73_22820"
                     /product="aspartate aminotransferase family protein"
                     /protein_id="WP_218440273.1"
                     /sec_met_domain="Aminotran_3 (E-value: 2.2e-87, bitscore:
                     286.8, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNLFNLRRPSPSLDDLVADDSFQSRGDTFSSECLMPSVERPKQVF
                     VRGQGSWLWDNDDRAYLDFSQGGGANSLGHSPKALVNAITAQAQSLINPGFGLHNRGML
                     NLAERLCAGTGSDQAYLLNSGSEACEAAIKLARKWGQQHRGGASRIIVANNACHGRSLG
                     TISASDSSTLVNRFEPQLSGFSHVPFNDLPALHAAVDERTVAIMLEPIQSEAGVIPATA
                     HYLKGVERLCRELGILLILDEVQTGIGRCGTLLAEQSFGVRADIVVLGKGLGGGVPVAA
                     LLARGRACCFETGEMTGTHHGNALMTAAGLVVIDSVQDKGFLKHVEESAQHLREGLQRL
                     SHRYGHGQLRGQGLLWGLTLSDDSADAVVKAALYEGLLLNAPQPDCLRFTPALTVSKAN
                     IDEMLLRLARAFSRVRTAQLQCRKGIAV"
     aSDomain        complement(14638..15582)
                     /aSDomain="Aminotran_3"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_KUF73_RS22815_Aminotran_3.1"
                     /evalue="3.60E-82"
                     /label="KUF73_RS22815_Aminotran_3.1"
                     /locus_tag="KUF73_RS22815"
                     /protein_end="360"
                     /protein_start="45"
                     /score="268.0"
                     /tool="antismash"
                     /translation="VRGQGSWLWDNDDRAYLDFSQGGGANSLGHSPKALVNAITAQAQS
                     LINPGFGLHNRGMLNLAERLCAGTGSDQAYLLNSGSEACEAAIKLARKWGQQHRGGASR
                     IIVANNACHGRSLGTISASDSSTLVNRFEPQLSGFSHVPFNDLPALHAAVDERTVAIML
                     EPIQSEAGVIPATAHYLKGVERLCRELGILLILDEVQTGIGRCGTLLAEQSFGVRADIV
                     VLGKGLGGGVPVAALLARGRACCFETGEMTGTHHGNALMTAAGLVVIDSVQDKGFLKHV
                     EESAQHLREGLQRLSHRYGHGQLRGQGLLWGLTL"
     gene            15887..16804
                     /locus_tag="KUF73_RS22820"
                     /old_locus_tag="KUF73_22825"
     CDS             15887..16804
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015097090.1"
                     /locus_tag="KUF73_RS22820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KUF73_22825"
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_218440274.1"
                     /transl_table=11
                     /translation="MDFKQLRYFVAVYEEGHVGRAAERLSISQPALSQQIRHLEQNLEV
                     SLFERSSKRLLPTLAAHTLYNHALPLLDGLQRAREALGNFKGQALRTLAIGVLQTVHTS
                     LVPQMLERVRKAQPHLVVQIYELTGLEIEKRLLNGSLDIGISYLPPRQPGLHGVMLYED
                     ELTLVIPADHPLREFKKVSMSQAAELPMLLLGEEFQIRQIWQAQLASLGRRPQVQAELN
                     NMVGILDSLPHTRLATVLPGRSQKEYGNQELLWKPLSEPRVPLKVGLVCRDVQRQQASL
                     ALLRTLLEEVMNRPDERLNSPPTM"
     gene            complement(17031..18809)
                     /locus_tag="KUF73_RS22825"
                     /old_locus_tag="KUF73_22830"
     CDS             complement(17031..18809)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006: acyl-CoA dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_249199.1"
                     /locus_tag="KUF73_RS22825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KUF73_22830"
                     /product="acyl-CoA dehydrogenase C-terminal
                     domain-containing protein"
                     /protein_id="WP_218440275.1"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 1.3e-13, bitscore:
                     45.2, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 6.7e-17, bitscore:
                     55.1, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 2.3e-23, bitscore:
                     76.6, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MADYKAPLRDMRFVLNEVFEVAKLWAELPALAETVDAETVEAILE
                     EAGKVTSKSIAPLSRAADEEGCHWADGAVTTPAGFPQAYQTYAEGGWVGVGGDPTYGGM
                     GMPKAVSAQVEEMVNSASLAFGLYPMLTAGACLSINNHASEELKAAYLPNMYAGIWAGS
                     MCLTESHAGTDLGIIRTKAEPQADGSYKVSGTKIFITGGEHDLTENIIHLVLAKLPDAP
                     AGPKGISLFLVPKFMVNADGSLGARNPANCGSIEHKMGIQASATCVMNFDEAVGYLVGE
                     PNKGLAAMFTMMNYERLGVGIQGLATGERSYQNAVEYARDRLQSRSPTGAQNKDKVADP
                     IIVHPDVRRMLLTMKASNEGGRAFSTYVAMQLDTAKFSEDATTRKRAEDLVALLTPVAK
                     AFLTDLGLETTVHGQQIFGGHGYIREWGQEQLVRDVRITQIYEGTNGIQALDLVGRKIV
                     GSGGAFYNLFADEIRHFTATASADLAEFTKPLNDAVTTLDELTAWVLDRAKNNPNEIGA
                     ASVEYLQAFGYTAYAYMWALMAKAAFGKEAQDDFYASKLGTARFYFARLLPRIHSLSAS
                     VKAGSEPLFLLDAAQF"
     misc_feature    complement(18934..18949)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 20.73"
                     /tool="antismash"
     gene            complement(18998..20794)
                     /locus_tag="KUF73_RS22830"
                     /old_locus_tag="KUF73_22835"
     CDS             complement(18998..20794)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006: acyl-CoA dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_249198.1"
                     /locus_tag="KUF73_RS22830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KUF73_22835"
                     /product="acyl-CoA dehydrogenase C-terminal
                     domain-containing protein"
                     /protein_id="WP_218440276.1"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 3e-16, bitscore:
                     53.7, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 6.6e-20, bitscore:
                     64.8, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 2.3e-26, bitscore:
                     86.3, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPEYKAPLRDMRFLIDHVFDFHSNYAALGATDASPDMVSAILEEG
                     AKFCENVLAPLNRIGDEEGCHFDNGVVTTPTGFKQAFAQYVEGGWHGLAADPAYGGQGL
                     PSSLGLVISEMIASSNTSWGMYPGLTHGAMSAIHAHGTEEQKQTYLSKLTAGQWTGTMC
                     LTEAHCGTDLGIIKTRAVPQADGSYAISGSKIFISAGEHDMSDNIIHLVLAKLPDAPAG
                     TKGISLFIVPKFLPDASGEAGERNGVTCGSIEHKMGIKASATCVLNFDEAKGLLIGEAN
                     KGLNCMFTMMNHARLGTGMQGLCLGEASFQGAIKYANDRLQMRALTGPKAPEKVADPII
                     VHPDVRRMLLTMKAFNEGNRALTYFTAQLLDAAHLSADEAARQDAEDLLAFLTPICKAF
                     MTDTGLEVTNLGMQVFGGHGFIREWGMEQLVRDCRIAPIYEGTNGIQALDLLGRKVLGS
                     QGKLLKGFTKIVHKFCATNAEHPQLASYVAQLNGLNQQWGELTTRIGVAAMKNPDEVGA
                     ASVDYLMYSGYIILGYLWLRMALVAQAQLEAGNGDADFCTAKLATSEFYFKRLLPRTAA
                     HRAAIEAGSDCLMRLPAELFSL"
     gene            complement(20880..22172)
                     /locus_tag="KUF73_RS22835"
                     /old_locus_tag="KUF73_22840"
     CDS             complement(20880..22172)
                     /EC_number="2.7.7.65"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1025: diguanylate cyclase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015097093.1"
                     /locus_tag="KUF73_RS22835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KUF73_22840"
                     /product="GGDEF domain-containing protein"
                     /protein_id="WP_218440277.1"
                     /transl_table=11
                     /translation="MPRSSAVRFSHFLPSLLLLLAGLAAAYVKDLNVFFTSLFNVLPTL
                     VLLLGGAYCAVYRRQRELFLMVTVYIAYFLLDTQTDYYRDNGKVRDDAAVVFHLCCLLL
                     PLLFGVFGAWQERTHLFQDMVARFAVLLAVGSVALGLEQSYPHALLIWLSEIRWPALHG
                     AWMSLIQLSYPVFIASFVLLAYQYWRNPRPLHAAQLVGLLGLFWMLPKTFILPFTLNIM
                     CSQVMLMIAAAVAHEAYQMAFRDELTGLPGRRALNERMQRLGRNYVLAMSDVDHFKKFN
                     DTHGHDVGDQVLRLVASKLSKIGGGGKAYRYGGEEFALVFAGKTLEECMPHLEVIRESI
                     ATYNIHLRNQDSRPQDDSQGRQRRSGSQASSVSVTVSIGVAERLEQRTPEQVLKSADEA
                     LYSAKGAGRNCVVAYGQTRRGAVRMDAATVE"
ORIGIN
        1 cctacgccaa agacaccgac cgccacgctt gggctgcgca ttacctgacg gcgatgagca
       61 aagctgtgat cgatgatgtg acgaaggtgc tggagcgagg gccggatcga ccgaagaagg
      121 gagcagatcc atcgaacttg cgaatgatca cagcagcgta gaagtcccaa aaatggcctt
      181 atcgatccct ttttgggact tgtccactga aaaagccaag cttccccttc ggcaaaagca
      241 gcgagagcac ttatgccaaa cctggtttac ccgcaacaca cctgccatgc ctatggttgc
      301 ttcagcagct aagcacaaat tgagcggggt tttttatacg gtttcgagcc attttctacc
      361 gagcctacgg ctccgcaaac atctgaaaac gtcgtaatcg acgaactcaa agtccaaaaa
      421 aagccgcgca atcgcgcggc tttttcgtac ccgcgattca gcccttactc aggcaacgca
      481 tacgcaatca cataatcccc ccgatccgtc gactgccgcg caccacccac cgtcagcagg
      541 atgtactgct tgcctgtctt cggcgataca taggtcatcg gacccgactg actacccacc
      601 ggcaaacgtg ccttccagat ctcattgccg ttgccggtat cgaaagcacg caggtagaaa
      661 tcctgagtcc ctgcgaagaa cagcaggccc gactgagtgg ccaaggaagc accaagcgtc
      721 ggcatgccga tggggatcgg caagtgcatg cgaatgccca gcgggccggt gtcttgtacg
      781 gtgccgaccg ggacttgcca catcagtttg tgggtcttga ggtcgatggc ggacatggtg
      841 ccgaacggtg gtttctggca tggaataccg gccgccgaga ggaagcgctc gcgcatggca
      901 ccgaacggcg tcccttcctg cggcaccacg cccatttcga taccgctggc cccggcaccg
      961 atcttgtcgc gagggatcat gtagttggcc aggcccaggc gcatgtcgtt gacgaacatg
     1021 tagttcgtgt tcggatcaac cgagacgctg ccccagttca tgccgcccaa ggagcccggg
     1081 aattgcaggg cgcggtccat gcccggcggg gtgtagacgc cttcgtggcg catgcctttg
     1141 aactggatgc ggcacatcaa ctggtcgaac ggcgtggcac cccacatgtc ggattcggtc
     1201 agggttttgt tgccgattga cggcatgtcc accgagaacg gttgggtcgg cgaatagcgc
     1261 tcgccgggca catggccttg tggaactgga cgctcttcaa cacgagcaat cggcacgccg
     1321 gtttcgcgat tcagcaggaa gatttcgcct tgcttggtga cttgcgccaa ggctggctgg
     1381 gtaccgccct tgtcgtccgg cacgtcgtac agcaatggtt gcgccggcag gtcgaagtcc
     1441 cacagatcgt ggtgagttgt ctggaagtgc cagcgcacct ggccggtttt cacgtcgatg
     1501 gcgacgatgg acgagttcca cttgtcgtcg aactcggtac gctggccgcc gaagaagtcc
     1561 ggggtggcgt tgccggtcgg tagatagacc agaccgagct tggcgtcgta ggacatggcc
     1621 gaccacacat tcggcgtgcc acgggtgtaa gtctcaccgg ctggcggacg tttggtggtg
     1681 ttcggattac ccggatccca cgcccacacc aactcaccgc tacgcacgtc gtaagcgcgg
     1741 accacacctg gcggttcgcc ggtggaatag ttgtccgcca cgcgaccgcc gacaatcact
     1801 acgttgcctg cgaccaacgg ggtcgaggtt tgctggtagt aaccgggctt cacttcgccc
     1861 atgtcggttt tcaggtcgac ggtgcctttg tttccgaact cttcgcacgg cttgccggtt
     1921 tcggcattga tggcgatcag acgggcatcg ccggtcggca aaaacagacg tttcgtacag
     1981 gcagttggct ggttgtccga agaagcaggg gtttcggaat agcccaggcc acggcaacgc
     2041 tgccagttgg gtgcggagcc ttgcgggtcg aacttccagc gctgggcacc ggtgtcggcg
     2101 tccagggcga agacttttcc gtaggcggtg caggtgtaga ccgtgtcacc gatttgcaac
     2161 ggggtgttct ggtcttcggc accggcgccg gtgctctgcg ggatgtcgcc ggtgcggaag
     2221 gtccaggcga cctgcaactt gtcgatattg cccttgttga tctggtccag cgcggcaaag
     2281 cgattgccgg cggtggtgtt gccccagtgc gcccagtctt tctgttcggt gcccggtgcg
     2341 accggtatta cggtgggttc actgctggcc ttgaccacgt gggttggcac gaacatgtaa
     2401 gccatggtcg ccacgatacc gacacccaga ataccggcca ctccatacgc gccacgacct
     2461 gcggacgcgc ctgaagcacg taccaatgtc ggataaatca gtacgacgac cagaccgatc
     2521 acagcgaagg tcagcacacg cgaaaccaat ggccaatact cgaatccggc atcccacacc
     2581 gcccagatcg ccgtcatgat cagtgccaga ccatacagcc aagcgcctgc cggtttgcgg
     2641 cgggcgatca tcagcccgga aaccagcatc gccagcccca tcagcaagaa gtaccagctg
     2701 ccgccaagcg caatcagata gccaccgccg ccagcgaggc cgagcccgat cagtgcaatc
     2761 agaacaccca gccccaccag caaccatttg ctgccggcgg cagccccaga attattcatg
     2821 tcggtaattt tccccatttg tgacaagggc ggaataatgt accacctagt tacttatggc
     2881 aatttgtcgc aggcagaaat gtaatgaacg gtagtgagac tagcccagac atccgtcacg
     2941 agcgctgttc agaatgtgcc tgtaacatgt ttgcccattg atctgtgctg ctggagatga
     3001 cgctttgcct gacactcgcc cgcccgttct tgacgaaatc gaccgccagt tgattgctgc
     3061 ccttcagctc aacgctcgcg aaagcgtcgc catgcttgcc cggcaactgg gcatcgcccg
     3121 caccaccgtc acttcgcgcc tggcgcggct ggaaaaggcc aaggtcatca ccggttacgg
     3181 cgtgcgcctt ggtcagcgcg tggtggacgg tgggttgcag gcgtacgtgg ggattactgt
     3241 gcagccgcgt tctggcaagg aagtgttgcg tcggttgagc gccatggctc aggtgcagca
     3301 gctgtgtgcg gtgagtggcg aatttgatta tgtggcctgg ttgcgcacgg actcgccaga
     3361 gcagctggat cagttgctgg atcagattgg cagcgtggat ggggtggaga agacgacgac
     3421 ttcaatcatc ttgagtagca agattgatcg tgggcagccg gtttgagtct ctggctgtag
     3481 agcttcggtg tctgggctgg cctcttcgcg agcaagctcg cttctacagt gggcagtgtg
     3541 catcgacaga tcgtcatact gatcaatata ttggcaaaac gacgacactt tgcgtcttat
     3601 taacgtgttc tacgctctct agaatggctg gcatcttttc ctatactcag acgcgcactc
     3661 cgcgttcggt cgctagcaag gtcagccatg aacaagaaca atcgccatcc tgcagatggt
     3721 aaaaaaccag tcaccatttt cggcccggac tttcctttcg ccttcgacga ctggattgaa
     3781 cacccggccg gtctgggcag cattcccgaa cacaatcacg gtgccgaagt ggcgattgtc
     3841 ggcggtggca ttgcaggctt ggtggccgcg tacgaattga tgaaactggg cctcaagcct
     3901 gtcgtctacg aagcctcaaa aatgggcggt cgtctgcgct cccaggcgtt caacggtgcc
     3961 gaaggcatca ttgccgaact cggtggcatg cgtttcccgg tgtcgtctac cgcgttttat
     4021 cactacgtcg acaagcttgg cctgcaaacc aaaccgttcc cgaacccgct gacacccgcg
     4081 tcgggcagca cggtgatcga cctcgaaggc caaacccatt acgcacaaaa actgtcggat
     4141 cttcccgcac tgttccaaga agtggctgat gcctgggccg acgctctgga agccggttcg
     4201 cagttttccg atatccagca agcgatccgc gaccgcgatg tgccacgcct gaaagagctg
     4261 tggaacaccc tggttccgct gtgggacgac cgcacgttct acgacttcgt cgccacctcc
     4321 aaagccttcg ccaagctgtc gttccatcac cgcgaagtgt ttggccaggt cggttttggc
     4381 acgggcggct gggactcgga cttccccaac tcgatgctgg aaatcttccg cgtagtgatg
     4441 accaactgcg acgatcatca gcacttggta gtcggcggcg tggaacaagt gccactgggt
     4501 atctggcgtc atgtgccgga acgttgcgcg cattggcctg cgggcaccag cctcagctcc
     4561 ctgcacaacg gcgcaccgcg caccggtgtg aaaaaaatcg ctcatgccga aggtggccgt
     4621 tttgccgtca ccgacaactg gggcgacacc cgtgaatacg cggccgtgct caccacgtgc
     4681 cagagctggc tgctgaccac ccagatcgaa tgcgacgaaa gcctgttctc gcaaaagatg
     4741 tggatggccc tggaccgcac ccgttacatg caatcgtcga aaaccttcgt gatggtcgac
     4801 cgcccgttct ggaaggataa agacccagaa accggccgcg acctgatgag catgaccctc
     4861 accgatcgcc tgactcgtgg cacctacctt tttgataacg gcgacgacaa accaggcgtg
     4921 atttgcctgt cgtactcgtg gatgagcgac gcgctgaaaa tgcttccgca gccggtggaa
     4981 aaacgcgtga aactggcgct ggatgcactg aagaagatct acccgaaagt cgatattgcg
     5041 gcgcgcatca ttggcgatcc gatcaccgtg tcgtgggaag ccgacccgca tttcctcgga
     5101 gctttcaaag gtgccctgcc cggccactac cgctacaacc agcgcatgta cgcgcacttc
     5161 atgcaggacg acatgcctgc cgaacagcgc gggattttca tcgccggcga cgacgtttcg
     5221 tggacgccgg cctgggtcga aggcgcggtg cagacgtcgc tcaatgcggt gtgggggatc
     5281 atgaaacact tcggcggtgc aactcacgcc gagaatccgg gtccaggtga tgtgttcaac
     5341 gagatcggac cgatcgccct gcccgagtaa gaggaatccg aaatgcgcgt agccctttac
     5401 caatgtccgc cactgcccct ggatgtcgcc ggcaatctgc aacgcttgca gcagcttgcg
     5461 caggaagcca aaggcgccga tttgctggta ctgccggaaa tgttcctgac cggttacaac
     5521 atcggcgtcg atgccgtcag cgtgctggcg gaggtgcaca acggtgagtc ggcgcaacaa
     5581 attgcgcgca ttgccaagtc tgccgggatt gccattttgt atggctatcc cgagcgcacc
     5641 gaggacgggc agatctacaa cgccgcgcag ttgatcgacg ccaacggcga gcgcctgtgc
     5701 aactaccgca agacgcactt gttcggtgac cttgaccgtt cgatgttcag ccccggcacc
     5761 aacgatttcc cagtcgttga actcaacggc tggaaactcg gcctcctgat ttgctacgac
     5821 ctggagtttc cggaaaacgc ccggcgtctg gcccttgatg gcgtcgagct gattctggtg
     5881 ccgacggcga acatgattcc tttcgacttc attgctgacg tcaccgtccg ctcccgcgcc
     5941 ttcgaaaacc agtgttacgt cgcctacgcc aactactgcg ggcacgaagg tgacatccat
     6001 tattgcggcc aaagcagcat cgccgcgccg gatggcagcc gcattgccca ggccggtctc
     6061 gatgaagcgc tgattgttgg cgagctggat cgtcagttga tggtcgattc ccgcgccgcc
     6121 aatcgctacc tgctcgatcg tcgccccgaa ctttacggcg acctgaacaa gcgctgacta
     6181 atccgctagc atgagcgctt ctctgttctg gaagtgctca tgtctgcgct gaaccacctt
     6241 cgcccccaca ctgaaaccct ggccaacggc ctgcgggtga cgctacgcca tgcgcctgaa
     6301 ttgaagcgtt gcgctgcggc attgcgggtt gctgtcggca gccatgatgt gccgttggca
     6361 tggcccggtc tggcgcattt tcttgagcat ctgctgtttc tggggaccga gcgttttccc
     6421 gccggccagg ggctgatggc ctacgtccag cgtcatggcg ggcaggtgaa tgcgcggacc
     6481 agcgaacgca ccaccgatta ctttttcgaa ttgccgcccc tggcgtttgc cggtgggcta
     6541 gaacgcctgt cagacatgct cgcccatccg tatatgaatc tggaggatca gcagcgggaa
     6601 cgtgaagtgc tgcaggcgga atttatcgcc tggtcgcagg acgcgacggc ccagcaacag
     6661 ttgacgctgt tcgatggggt tgctgaaact catccactgc ggggctttca cgcgggtaat
     6721 cgcgacagtc tgccggtgcc acaaccggag tttcagcagg ccttgctgga tttttttcag
     6781 cagtactatc aaaccggaca aatgacgctg agtctggtcg gaccacagaa tcttgaagaa
     6841 ctgaaagcac ttgcccaggc attcgctgag gccattcccg agggaaattc gatcgcgcaa
     6901 caggctgcta cgccgctgat gggcgattcg gataaaagtt atcagcaggt gaacgagcgc
     6961 cgactggatc tgctgtttgc tcttgaagcg ctacccgatt catcgcccga agcattggag
     7021 ttcctgtgcc attggctcaa cgctgcgaaa cccgaagggt tgctggctga attgcaaaac
     7081 cgcgggtggg ccgaaaagtt gaaagccgcg ccgttgtatc aatttgccgg gcaagccttg
     7141 ctgcacatcg agttcacgcg ggacaccaat acacagccga cggcgattcg cgacctgtta
     7201 atggattggc tgggcttctt cgctcagcaa gactggagcg gattgcgcga tgaatacgca
     7261 gctctgctcc agcgccaaca gcaagtcagc agcgccctgc aattggcccg actggacagc
     7321 gaacggcacg aagccgggct atccgaacac ggcgtgacag ccctccagca aatcctgcaa
     7381 caactccgcg ctgtggataa cttcacgggc caatggcaac tgccgacacc caatccgttc
     7441 ttgcgcgccg agtctgcggc accgaacgcc gggttgattc gcggccagac cagcgcccac
     7501 cgtggcttgc gcacatttgc acaggatcgc tcgcgcagtc gccgcgaacg ttcgccgatg
     7561 cagttcagcc aagcgttgcc ggataacagc gctgaaggtg cggtgtacgt gcgctggcgc
     7621 ctcgacgcag cacctggcaa tcaccttcaa tcaaggctgg caaaacatct gcaaccgcta
     7681 tgcgaagaag cgcatcaggc aggcgtggat gtttccttca gcgcagcggg caacgaatgg
     7741 cggctgaaaa tgacggggct acaggagccg atgcctaccg tcctggaaca cgtgctgaag
     7801 gaactggcga acaccgatgc cgatttcctg tgtgatgaat caacagccgt cgcgttgatg
     7861 cctattcggc aattgctcaa ggcattgccc gatcattgcc ttgaacaaac cgccgtatcg
     7921 gacgacgcga agcaactctg gtcgagcgcc cgctgggatg gcctggcaat cggcctgtcg
     7981 gctcagaccc aagcggcaat gggcctggcg ctgagccgta tacccggcac tccggacaat
     8041 cagctgacgc tgccgccatc gattcacacg caacatttgt ggcacaccgt cgctaccggc
     8101 tccagcgaac acgcattgct gttgttctgt ccgacaccct cccaagaaat tgccgacgaa
     8161 gccgcgtggc gtttactcgc acacgtctgt cagacgccgt tctaccaacg cctgcgggtg
     8221 gaattgcaac tcggctacgc ggttttcagt gacctgcgcc agattcacgg gcaaaccggt
     8281 ctgctgttcg gtgtgcaatc gccgagcgtc gctccgctgg atctactgct gcacattgaa
     8341 cagttcctta gcggattgcc ggacatgatc cgcaacctcg acgacatcag cttcatcgca
     8401 ctgcgtcaga ccttggctaa ccaattcgaa agcaccgcca tgcccaacgc cgaagcggcc
     8461 gagctgctct ggcagggcaa actggccggc cgctcgtcgg attatctgaa acagttaccc
     8521 caagtgattc tgcaaattga tcaagcggcg ctcgtgggtg cggcccaacg gctgaatcag
     8581 gccgaaggcg gttggcgttg cctggccagc gcggcttgcc cggggtcacc ctggcaagtg
     8641 gcaaaatgat cattaccggg gctgcaatga gctttctcaa agtttcatgg gcaattactc
     8701 agcaatattg agtaacatag ctacctaact atctgaacat ctcctgctgg aggtggacta
     8761 tatgtatagg tctcaactgt cccatcaacc taaggagcgc ccccatggcc tggaccaaac
     8821 ctgcttacac cgacctgcgt atcggctttg aagtcaccat gtacttcgcc agccgttgat
     8881 ctctgccttg gcagaaatgc agtacaacgc ctcggttatc cgaggcgttt tattttcagc
     8941 gttaaaatga tggagcgccc atgtttgtcc agattctagg ttccgccgct ggcggcggtt
     9001 tcccccaatg gaactgcaac tgcgtgaact gcgcaggctt tcgcgacggc agcctgaatg
     9061 ccagggcgcg tacccagtcg tccatcgcga tatccgatga cggcgtaaat tgggtgctct
     9121 gcaacacgtc cccggacatc cgcgcccagc tccagagctt cgccccgatg caaccgggcc
     9181 gcgccctgcg tgacaccggc atcagcgcga tcattctgat ggacagccag atcgaccaca
     9241 ccaccggcct gctgatgttg cgtgaaggtt gcccgcatca ggtctggtgc accgacatgg
     9301 tccatgaaga cctgagcacc ggtttcccgt tgttcaccat gctgaatcac tggaacggcg
     9361 gcctgaactg gaaccgcatc gaactcgacc agagcttcag catcccggcg tgcccgaacc
     9421 tgcgcttcac cccgctgcca ctgcgcagtg ccgcgccacc ctactcgccg catcgcttcg
     9481 acccgcatcc gggcgacaac atcggcctga tcgtcgaaga cctgggcaca ggtggcaaat
     9541 tgttctacgc gccaggcctg ggcaaggtcg acgcgccatt gctggaaatc atggccggca
     9601 gcgattgcct actggtggac ggcacgctgt gggacgacga tgaaatgcag cgccgcggcg
     9661 ttggcacccg ttccggtcgg gaaatgggcc acctggcgca gaacggtccc ggcggcatgc
     9721 ttgaagtgct ggggcaattg cccaaacagc gcaaagtgct tatccacatc aacaacacca
     9781 acccgattct cgacgaggat tcgccagagc gggcggagtt ggatcggcgt gatgtagaag
     9841 tggcgtacga cggcatgagt attgtgctgt agctgacggc ctctgcgcgg gcaagcctcg
     9901 ctcctgcaag ggtgccatcc aacctgtagg agcgaggctt gcccgcgaag cgtccaacca
     9961 ggcaccaaag aatccaccgg ttgtactccg gagaaccgca atgactgaca ccccaatgtc
    10021 ccccgacgaa tttgaagccg ccctgcgcgc caagggcgcc tattaccaca tctaccaccc
    10081 ctaccacgtg gcgatgtatg aaggccgggc gacccgcgag cagatccagg gctgggtcgc
    10141 caaccgcttc tactatcagg tgaacatccc cctgaaagac gccgcgatcc tcgccaattg
    10201 cccggaccgc gagatccgtc gcgagtggat tcagcgcctg ctcgaccatg acggcgctcc
    10261 cggtgaagac ggcggcatcg aagcctggct gcgcctcggt caggcggtcg gcctcgatcc
    10321 ggatcaactg cgttcccagg aactggtgct gcccggcgtt cgtttcgccg tggacgctta
    10381 cgtcaatttc gcccgccgcg ccagttggca ggaagccgcc agcagctctc tgaccgagct
    10441 gttcgcgccg cagatccacc agtcgcgcct ggacagttgg ccacagcatt acccgtggat
    10501 cgacccggcc ggctacgagt atttccgcac gcgcctgggt caggcgcgcc gcgatgtcga
    10561 gcatggtctg gcgatcacct tgcagcacta caccacccgc gagggccaag agcgcatgct
    10621 ggaaattctc cagttcaaac tggacattct ttggagcatg ctcgatgcca tgagcatggc
    10681 ttacgagctg aaccgcccgc cgtatcacag cgtgaccgaa caacgggtct ggcataaagg
    10741 aatcacctta tgagcttcga tcgcagcaag accccgacct ggcgtcccgg ctaccgtttc
    10801 cagtacgaac ccgcgcaaaa aggccatgtg ctgctgtacc cggaaggcat gattaaactc
    10861 aatgaaagcg ccgcgctgat tggcgggttg attgatggcg aacgcgacgt cgccgcgatc
    10921 attgtcgaac tcgaccaaca gttccccggc gtgcccgagc tcggtgatga tatcgagcaa
    10981 ttcatggagg tcgcccgtgc tcagcactgg atcgaacttg cctgacagcg cgtcagacaa
    11041 gttaccgccc aaaccggaaa tcggcctgcc gctgtggctg ctggccgaac tgacctatcg
    11101 ctgcccgctg caatgcccgt actgctccaa cccactggac ttcgccgagc aaggcaagga
    11161 attgagcacc gagcagtggc ttaaagtgtt tcgcgaagca cgagagatgg gcgcagcgca
    11221 gttgggtttt tccggcggtg aacccttggt gcgtcaggac ctcgcagaat tgattgccga
    11281 ggcgcgcaag ctgggtttct acaccaacct gatcacctcc ggcatcggcc tgaccgagca
    11341 aaaaatcagc gacttcaaga aggccggtct cgatcacatt cagatcagtt tccaggccag
    11401 cgacgagcaa gtgaacaacc tgttggctgg ctcgaagaag gcctttgcgc agaagctgga
    11461 aatggcccgc gcggtgaagg cgcacggcta tccgatggtg ctcaacttcg taacccatcg
    11521 gcacaacatc gataagatcg accgcatcat cgagctgtgc atcgcccttg aggcggactt
    11581 cgtcgaactc gccacttgcc agttctacgg ctgggcgcag ctcaatcggg ttggtttgct
    11641 gccgactcgg gaacaactgg tgcgcgccga acgcattacc aatgagtacc gcgccaaact
    11701 ggaagccgaa gggcatccgt gcaaactgat tttcgtcacg ccggactatt acgaagaacg
    11761 cccgaaagcc tgcatgaatg gttggggcag tatttttctg acagttacgc cagatggtac
    11821 cgcgctgcca tgtcatggcg cccgacaaat gccagtgcag tttcccaatg tgcgcgacca
    11881 cagcatgcag cacatctggt acgactcctt cggcttcaac cgctttcgcg gccacgactg
    11941 gatgcccgag ccgtgccgct cctgcgacga gaaagaaaaa gactttggcg gctgtcgctg
    12001 ccaggcattc atgctcacgg gtgacgcgag caacgccgac ccggtgtgca gcaagtcgca
    12061 gcatcacggc gtgattctca aggctcgcga agaagccgag cacgcgactc agaccatcga
    12121 acaactggcc tttcgcaatg aacgaaactc acgcctcatc gccaaaagct gaaccgttca
    12181 gcgccgccaa cgccgtcgcg gccggcatcg actttgccga gttgcagctg ggcgtccatg
    12241 gtttgttctg gaacgaatac cgaccggaag atgccgcctg ccggatctgg cattggcgcg
    12301 acggcgtggc gaaatgtctg acgccatcag gcttcagcgt gcgcagtcgg gtgtacgaat
    12361 atggcggtgg tgcgttttgt ctgaccgacg acggagtggt tttcgtcaac gaggctgacc
    12421 agcagcttta tcgtcaatca ctgcacggcg agcctgcagt cctgacgtcg ggtgtgtgcc
    12481 gttacggcga cttgcagttt gccgatggtc aggtgctggc agttgaagaa catcgtgacc
    12541 ggcatcgatt ggtagcgatt gatctggccg acggctcgca tcatttgctg gccgaaggtg
    12601 ctgactttta cgctgcaccg acattgagtc ctgacgctcg gcgcctggcc tggatcgagt
    12661 ggagccgccc ggatcagccg tggaccgcga ctcgcttgat ggttgccgaa cgcctagacg
    12721 atggaggttt tgccccgccc cgttgcgtgg ccggcgataa cgcccaagag tcactgcaac
    12781 aacctcgatt cgatgacagc ggcaggttgt tttgtctgac ggatcgcggc ggtttctggc
    12841 agccttggat ggagtccgca aacggtctca gctcattacc aagtgccgcc gccgaccatg
    12901 gtccggcgcc ttggcaactt ggcggctgca cctggttgcc gctgggcgaa acccgctatc
    12961 tggccagttg gagcgagggc ggttttggcc gattgggtct ttgcggcgcc acgtgcgaag
    13021 atttcaccgg cgactacagc cgtttccgtc atctcgccct ggatgagcat ttcatttact
    13081 gcattgcggc atcgccgatc agttcgtcag ccgtgatagc catcgaccgt cacactcgcg
    13141 aagtgaaaaa actggccggc ggtattacac cgctgcctac ccaacagatc agcgttccac
    13201 aaaccctgcg ctacccgagc ggctccggcg aagcccacgg ctttttctac ccggcgatga
    13261 cctcggatgc aaaaccgccg ctggtggtat tcatccacgg cggcccgaca tcggcgtgct
    13321 atccgatgct ggacccgcgc atccagtact ggacgcaacg cggcttcgcc gtcgccgacc
    13381 tcaattatcg cgggagcagc ggctacggtc gggcctatcg ccaggcgctg catttgagct
    13441 ggggtgatgt cgatgtcgaa gacgcttgcg cggtggtcag ccatctcgcc gaacgcggat
    13501 tgatcaatgg tgacaaggca tttattcgcg gcggcagcgc gggcggttac accacgcttt
    13561 gcgcgctggc gttccacaag gtatttcggg ctggtgccag tctttatggc gtcagcgatc
    13621 ctgttgcgct aggtcgtgcg acgcacaaat tcgaaggcga ctatctggat tggctgatcg
    13681 gcgatcctgc gcaggatgcc gagcgctacg ccgctcgaac gccgttactg catgcgagca
    13741 acatcagcgt gccggtgatt ttttttcaag gggaactgga cgcggtggtc gtgccgcaac
    13801 agacccgcga tatggtctcg gcacttcaga gcaacggtat tctggtagaa gcccattact
    13861 acgctgatga gcgccatgga ttccgcaagg cggtaaatca ggctcacgcg ctggagcagg
    13921 agtggttgtt ttatcggcgg gttatggaga tcgccggttg aaattgtgga gttcccttcg
    13981 cgggcaagcc ccgctcctac agggatatca tttgtatctg taggcgcgag gcttgcccac
    14041 gaaagcgcct gacatcaggc cccgtactca acgcttggcg atgatataaa ccgcatgcac
    14101 gatcccaggg atgtaaccgc acaacgtcag cagaatattc agccagaacg ccccgccaaa
    14161 ccccacctgt agaaacacac ccaatggcgg cagcagaatg gcgatgatga tgcgaatgaa
    14221 atccatgggg caactcctga tcgaaatcgg ctcatgcgag ccctacagct aatcgacctg
    14281 tgccgttggt cagggttcac ttcaataatc ctgtgcacca ggcgtcgcga caagtttcgc
    14341 agccacaaaa aaacgcccca cgccaaaaaa tacaggcgtg gggcgtgcgt tataccgcga
    14401 gacggttcgg gaatttctgt agggcgtgtc tgatcagacg gcaatccctt tgcggcactg
    14461 cagttgcgcg gtgcgcacgc gggagaaggc gcgggccagg cgcaggagca tttcgtcgat
    14521 gttggctttg ctgacagtga gtgccggggt gaagcgcagg cagtcgggtt gcggagcatt
    14581 gagcagcaat ccttcgtaca acgctgcttt gactacggca tcggccgaat cgtcggacag
    14641 ggtcagtccc cagagcagtc cttgaccgcg taactgacca tggccgtagc gatgggacaa
    14701 ccgctgtaaa ccttcgcgca ggtgctgggc gctttcctcg acgtgcttaa gaaatccttt
    14761 gtcttgcaca ctgtcaatta cgaccagccc cgccgctgtc atcaacgcat tgccatgatg
    14821 ggtgccggtc atttcgccgg tttcgaaaca gcaggccctg ccccgcgcca gcaatgccgc
    14881 tacgggaaca ccaccgccca gtcctttgcc gagcacgacg atatcggcgc ggacaccgaa
    14941 ggactgttcg gcgagcaagg tgccacaacg accaatgccg gtttgcactt cgtcgagaat
    15001 cagcagaatg ccgagttcac ggcacagccg ttcgacgcct ttgaggtagt gcgcggtggc
    15061 gggaatcacc ccggcttcgc tctggatcgg ttcgagcatg atcgccacgg ttcgctcatc
    15121 cacggccgcg tgcagcgccg gcagatcatt gaacggaacg tggctgaagc ctgacaattg
    15181 cggttcgaac cggttgacca gtgtcgaact atccgacgct gaaatcgtcc ccagactacg
    15241 accgtgacag gcgttgttgg cgacgatgat ccgtgatgcg ccaccccgat gttgctggcc
    15301 ccatttgcgt gccagcttga ttgccgcttc acacgcttca ctgccgctgt tgagcagata
    15361 cgcctggtca ctgccggtgc cagcacacaa tcgctcggcg aggttgagca tgccgcgatt
    15421 atgcagacca aaaccggggt taatcagcga ttgagcctgt gccgtgatgg cgttaaccag
    15481 tgccttgggg ctgtgcccga ggctgttggc gccgccaccc tgtgaaaaat ccagataggc
    15541 acggtcatcg ttgtcccaca accaggaacc ctgaccacgg acaaaaacct gtttcggccg
    15601 ctcgacactg ggcatcagac actcgctgga aaaggtatcc ccccgggact gaaaggagtc
    15661 gtccgccacc aggtcatcca gacttgggga cgggcgacga aggttgaaca gattcatgcc
    15721 ttcaaccctc gtttgagatt ttttgtctta cctatgcaaa caccatcgaa acaatcggta
    15781 ttcatcgcgc tctgtggccc tgtaagcctt gtggatgcgg ttagactagg ctcagacgag
    15841 gcgtccagcc atttcgattt ttaagcattt tcgataagta tttcttatgg atttcaagca
    15901 actgcgttat ttcgtcgcgg tctacgaaga aggtcacgtg gggcgtgcgg ccgagcgcct
    15961 gtccatctcc cagcctgccc tgtcgcagca gattcgccac ctcgaacaaa acctcgaagt
    16021 gagcctgttc gagcgcagca gcaaacgcct gctgcctacc ctcgccgccc acacgctgta
    16081 caaccatgcc ctgcctcttc tcgacggttt gcaacgagcg cgggaagcgc tgggtaactt
    16141 caagggccaa gcgttgcgca cgctggccat tggtgtcttg caaaccgtcc acaccagtct
    16201 cgtgccacaa atgctcgagc gcgtacgcaa ggcccagccg catctggtgg tgcagattta
    16261 cgaactgacc ggattggaaa tcgaaaagcg cttgctcaac ggctcgctcg acattggtat
    16321 cagctacctg ccgccgcgcc agccgggttt gcatggtgtg atgctgtacg aagatgaact
    16381 gaccctggta atccctgcgg atcatccatt gcgggaattc aagaaagtgt ccatgagtca
    16441 ggccgcggaa ttgccgatgt tgctgctggg tgaagagttt cagatccggc aaatctggca
    16501 agcgcaatta gccagcctcg gacgtcgtcc gcaagtacag gcagaattga ataacatggt
    16561 ggggattctc gacagcctgc ctcacacccg gctggcgacc gtattgcctg gacgctcgca
    16621 aaaggaatac ggcaatcagg aactactgtg gaaacccttg agtgagccgc gcgtgccact
    16681 gaaagtcggg ttggtgtgtc gggatgtgca acggcaacag gcctcgctgg cgttgttgcg
    16741 gacattgctg gaggaagtga tgaaccggcc ggatgaacgc ttgaacagtc cgccgacgat
    16801 gtgaaacttt tctcgaggca aaagaaaacc ccgccgaagc ggggctttgc agactgtttc
    16861 cctgacatcc atttcactcc gccgtcctgg cagaatccta cgtgtccgtg ttgttgcttt
    16921 gcgcttcctg cgctacgtcc atgtgaagta gattaactgt ggatccaatt taaacctatg
    16981 ggagaacagc agcacgtcat gtaagagaat gcttacatga cgttacatct tcagaactgc
    17041 gcggcatcca gcagaaacag cggctcgctg ccggccttca ccgacgcact cagcgagtga
    17101 atccgcggca gcagacgggc gaaatagaat cgcgccgtac ccaatttact ggcgtagaaa
    17161 tcgtcctgcg cttctttgcc gaaggcagcc ttggccatca gcgcccacat gtaggcgtaa
    17221 gccgtgtaac cgaatgcttg cagatactcg actgacgccg cgccgatttc attcgggttg
    17281 tttttagcgc ggtccagtac ccaggcggtc agctcgtcga gggtggtcac ggcatcgttc
    17341 agcggtttgg tgaactccgc cagatcagcg ctggcggtgg cggtgaagtg gcgaatctcg
    17401 tcagcgaaca ggttgtagaa cgccccgccg ctgccgacaa ttttacgccc gacgaggtcc
    17461 agcgcctgaa tgccgttggt gccttcgtag atttgggtga tgcgcacatc acgcaccaac
    17521 tgttcctggc cccactcgcg gatgtaaccg tgaccgccga aaatctgctg gccgtgaacc
    17581 gtggtttcca gaccaaggtc ggtaagaaac gctttggcca ccggagtcag caacgctacc
    17641 aggtcttccg cgcgcttgcg ggtggtggcg tcttcgctga acttggcggt gtccagttgc
    17701 atggccacat acgtcgagaa agcacgaccg ccttcgttcg aggctttcat ggtaagcaac
    17761 atgcgacgca cgtccgggtg gacgatgatc gggtcagcca ctttatcctt gttctgagca
    17821 ccggttggcg agcggctttg cagacggtca cgggcatatt cgacagcgtt ctggtaagag
    17881 cgctcaccgg tagcgaggcc ctgaatgcca acccccagac gttcgtagtt catcatggtg
    17941 aacatagccg caaggccttt gttcggctcg ccgaccaggt aacccacggc ttcgtcgaag
    18001 ttcatcacgc aggtcgcgga cgcctggatg cccattttgt gctcgatcga accgcagttc
    18061 gccgggttgc gtgcgcccag gctgccatcg gcgttgacca tgaacttcgg caccaggaac
    18121 agcgaaatgc ccttcggccc ggccggagcg tccggcagtt tggccagcac caggtgaatg
    18181 atgttctcgg tcaggtcgtg ttcgccgccg gtgatgaaaa tcttggtgcc actgaccttg
    18241 taggaaccgt cggcctgagg ttcggccttg gtgcggatga tccccaggtc ggtgccggcg
    18301 tgcgactcgg tcaaacacat ggaaccggcc cagataccgg catacatgtt cggcaggtac
    18361 gcggccttca gttcttcgct ggcgtggttg ttgatcgaca ggcaggcacc ggcggtcagc
    18421 atcgggtaca ggccgaacgc caggctggcg gagttgacca tttcttcgac ctgggccgaa
    18481 acagccttgg gcatgcccat tccgccgtag gtcggatcac caccgacacc gacccaaccg
    18541 ccttcagcgt aggtctgata agcctgtgga aaacctgccg gcgtggtgac ggcaccgtcc
    18601 gcccagtggc aaccttcttc gtcagccgca cggctcaggg gcgcgatgct cttgctggtg
    18661 accttgccgg cttcttcgag aatggcttcg acggtttccg catcgacggt ctcggccaac
    18721 gctggcagtt cggcccaaag tttggcgacc tcgaaaactt cattgaggac gaagcgcata
    18781 tcgcgcaggg gcgctttgta gtcagccatg gcaaacctcg caagatctat acaggtgatt
    18841 cgtaggagtg gtgctttcgt tgggcccgag tgtaacccaa caacttttgc gacacatagg
    18901 gtcagccggt gaccgttttg taatttttag tcaccgacca ttcagtcaca aaaaaagccc
    18961 gcggtcaggc gggctccttt gtatcggatt taaaagatta aagtgaaaac aactccgccg
    19021 gcaggcgcat caggcaatca ctacccgcct cgatggctgc ccgatgagcg gcagtgcgtg
    19081 gcaacaaacg cttgaagtaa aactcgctcg tcgccagttt ggccgtgcag aaatccgcat
    19141 cgccgttgcc ggcctccagc tgtgcctggg ccaccaacgc catgcgcaac cacaaatagc
    19201 caaggatgat gtagccgctg tacatcaggt aatccacaga ggcggcaccc acttcatcag
    19261 ggtttttcat cgcagccacg ccgatcctgg tggtcaactc gccccattgc tggttcaggc
    19321 cattgagttg tgccacatag cttgccaact gcggatgctc ggcgttcgtc gcgcaaaact
    19381 tgtggacgat ttttgtgaat cccttcagga gtttgccttg gctgccgaga actttgcgcc
    19441 ccagcaagtc cagcgcctga atgccgttgg tgccttcgta gataggcgcg atgcggcaat
    19501 cacgcaccag ttgctccata ccccattcac gaatgaaacc gtggccaccg aacacttgca
    19561 tgccgaggtt ggtcacttcc aggcctgtgt cggtcatgaa agccttgcag atcggggtca
    19621 ggaacgccaa gaggtcttcg gcatcctggc gcgccgcctc atctgcactc aggtgtgcag
    19681 cgtccagcaa ctgcgccgtg aagtaggtca gcgcccgatt gccttcgttg aaggccttca
    19741 tggtcagcag cattcgccgc acatccggat gaacgatgat cgggtcggca actttctccg
    19801 gtgctttcgg gcccgtcaat gcgcgcatct gcaagcggtc gttggcgtac ttgatcgcgc
    19861 cctggaaact cgcttctccc agacacaaac cctgcatgcc cgtgcccagg cgcgcgtggt
    19921 tcatcatggt gaacatgcag ttcaggccct tgttcgcctc gccgatcagc aagcctttgg
    19981 cttcgtcgaa attcagcacg caggtggccg acgccttgat gcccattttg tgttcgatag
    20041 agccgcaggt cacaccattg cgctcgccgg cctcacctga ggcatcgggc aggaatttag
    20101 gcacgatgaa cagcgaaatg cccttggtcc cggctggcgc gtccggcaat ttcgccagca
    20161 ccaggtgaat gatgttgtcg ctcatgtcgt gctcaccggc ggagatgaaa atcttgctgc
    20221 cggagatcgc gtaactgcca tcagcctgtg gcacggcgcg ggtcttgatg atgcccaggt
    20281 cggtgccgca atgggcttct gtcaggcaca tggtgccggt ccattggccg gcggtgagtt
    20341 tgctcaggta cgtctgtttt tgctcttcag tgccatgggc atggatggcc gacatggccc
    20401 cgtgggtcag gccggggtac atgccccagg aggtgttgct ggacgcgatc atctcgctga
    20461 tgaccaagcc cagagagctt ggcaatccct gacctccgta ggctggatcc gccgccagac
    20521 catgccagcc gccctccaca tattgtgcga aagcctgctt gaagcctgtc ggcgttgtga
    20581 ccacgccatt gtcgaaatgg cagccctctt cgtcgccgat acggttaaga ggcgccagca
    20641 cgttctcgca gaatttcgca ccttcttcga ggatcgcact gaccatgtcc gggctggcgt
    20701 cagtagcacc cagcgcagcg tagttgctgt gaaagtcgaa gacgtggtcg atcagaaagc
    20761 gcatgtcgcg caggggagct ttgtactcgg gcatggtcat tctccgtcag cagattgctc
    20821 aaatctactg ccgccgacca cgcctcacaa tcacagtcca gacgctgaat gcgccatcat
    20881 cactcaaccg tagcggcgtc catacgcaca gcgccacggc gggtctgacc gtacgcaacc
    20941 acgcagttac gcccggcgcc cttggcgcta taaagggcct cgtccgccga tttgagcact
    21001 tgctccgggg tgcgctgttc aagccgctcg gccacgccaa tactgacggt gaccgacaca
    21061 ctcgaagcct gggaaccgga acgacgctga cgaccctgac tatcatcctg agggcggctg
    21121 tcctggttac gcaggtgaat gttgtaagtg gcgatggatt cgcggatgac ttcgaggtgc
    21181 ggcatgcact cttcgagggt tttgccggca aacaccaggg cgaattcctc accgccgtag
    21241 cgatacgcct taccgccccc gccgattttc gacagcttgc tggccaccag tcgcagtacc
    21301 tggtcgccga catcatggcc gtgggtatcg ttgaatttct tgaagtgatc gacgtcgctc
    21361 atggccaaca cgtaattgcg tcccagccgt tgcatgcgtt cgttcaaggc gcgacgcccc
    21421 ggcaggccgg tgagctcgtc acggaacgcc atttgatagg cctcgtgcgc aacggcggcg
    21481 gcgatcatca gcatcacctg gctgcacatg atgttcaggg tgaacggcag gatgaaggtt
    21541 ttcggcaaca tccagaacag tccgagcagc cccaccagtt gtgccgcatg cagcggtcgc
    21601 gggttgcgcc agtactgata ggccagcaac acgaacgagg caatgaacac cggataggac
    21661 aactggatca ggctcatcca ggcaccatgc aacgctggcc aacggatctc cgacagccag
    21721 atcaacagcg catgcgggta actttgctca agcccgagtg ccacgctgcc cacggccagc
    21781 aataccgcaa agcgcgccac catgtcctgg aacagatggg tacgttcctg ccacgcgccg
    21841 aacacgccaa acagtagcgg cagcagcagg caacataaat gaaagaccac cgctgcgtcg
    21901 tcgcgcactt tgccgttgtc gcggtagtag tcggtctggg tgtcgagcag gaagtaggca
    21961 atgtacaccg tgaccatcag aaacagttca cgctgacgtc gataaaccgc gcagtaagca
    22021 ccgccgagca acagcaccaa ggttggcagc acgttgaaca gcgaggtgaa gaagacgttc
    22081 agatccttga cgtaagcagc cgcaagcccc gccagcaaca gcagtagtga cggcaggaaa
    22141 tgactgaaac gtacagcgga agaacgcggc aa
//
