LOCUS       NZ_JAHTMR010000001     10840 bp    DNA     linear   CON 21-AUG-2024
DEFINITION  Pseudomonas sp. PD9R Contig_1_consensus_sequence, whole genome
            shotgun sequence.
ACCESSION   NZ_JAHTMR010000001
VERSION     NZ_JAHTMR010000001.1
KEYWORDS    WGS; RefSeq.
SOURCE      Pseudomonas sp. PD9R
  ORGANISM  Pseudomonas sp. PD9R
            Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales;
            Pseudomonadaceae; Pseudomonas.
REFERENCE   1  (bases 1 to 986672)
  AUTHORS   Tournay,R., Firrincieli,A., Parikh,S. and Dominic,S.
  TITLE     Isolation and characterization of arsenic-tolerant endophytes and
            the potential of endophytic biofilms in arsenic tolerance
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 986672)
  AUTHORS   Tournay,R., Firrincieli,A. and Doty,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUL-2021) School of Environmental and Forest Sciences,
            University of Washington, 4000 15th Ave NE, Seattle, WA 98195, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 23-JAN-2020
            Assembly Method                   :: Geneious Prime v. 2020.0.3
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 158.0x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_019200975.1-RS_2024_08_21
            Annotation Date                   :: 08/21/2024 05:49:47
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,297
            CDSs (total)                      :: 6,222
            Genes (coding)                    :: 6,093
            CDSs (with protein)               :: 6,093
            Genes (RNA)                       :: 75
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 61
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 2 of 129
            Pseudo Genes (frameshifted)       :: 24 of 129
            Pseudo Genes (incomplete)         :: 110 of 129
            Pseudo Genes (internal stop)      :: 10 of 129
            Pseudo Genes (multiple problems)  :: 15 of 129
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 02:28:33
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 496490
            Orig. end                         :: 507330
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JAHTMR010000001.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..10840
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..10840
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..10840
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[5000:5840](+)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..5840
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     misc_feature    418..431
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 18.87"
                     /tool="antismash"
     gene            complement(988..1830)
                     /locus_tag="KUF73_RS02280"
                     /old_locus_tag="KUF73_02280"
     CDS             complement(988..1830)
                     /GO_function="GO:0070403 - NAD+ binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008021754.1"
                     /locus_tag="KUF73_RS02280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KUF73_02280"
                     /product="NAD-dependent protein deacetylase"
                     /protein_id="WP_218436411.1"
                     /transl_table=11
                     /translation="MLDHPIREQLDRLQQLMADRPFVVLTGAGISTPSGIPDYRDNQGV
                     RRGRQPMMYQEFLSAPESRRRYWARAMLGWPRVRQAQPNVAHDTLARLQSTRQISGLIT
                     QNVDTLHDQAGSHDVIELHGSLHRVLCLDCGKRSERDSIQHLMEAQNPYLAGVDAVQAP
                     DGDTLLDAAFEARFQVPHCPHCAGERMKPDVVFFGENVAQETAAKAMAAVEKAAGLLVV
                     GSSLMAYSAFRLCRAVVDQGKPLLAINLGKTRADDILDLKIEGSCEQLLPLLAQRLFN"
     gene            complement(1976..3022)
                     /locus_tag="KUF73_RS02285"
                     /old_locus_tag="KUF73_02285"
     CDS             complement(1976..3022)
                     /EC_number="2.1.-.-"
                     /NRPS_PKS="Domain: oMT (164-270). E-value: 6.7e-12. Score:
                     36.1. Matches aSDomain: nrpspksdomains_KUF73_RS02285_oMT.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1042: O-methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019582146.1"
                     /locus_tag="KUF73_RS02285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KUF73_02285"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_218436412.1"
                     /transl_table=11
                     /translation="MDEARLNDFMGKLVNDMGGAAMLANVILGEELGLYRAMADSQPTS
                     PETLADKTGCNPRLVREWLSAHAASGYMEHVDGQFRLPEEQALALAIEDSPVYIAGGIG
                     VVASFFHDKDKLVKAMRGDGALPWGDHHPCMFSGTERFFRPGYKAHLIAEWLPALDGVV
                     AKLEAGAKVADIGCGHGASTVIMAQAFPDSRFVGFDYHAPSVTVATQRAEEGGVSSRAR
                     FFQGTAKSYPGDDYDLVCYFDCLHDMGDPVGAAKHAYESLKPDGTVLLVEPFANDSLDD
                     NITPVGRLFYAASTFICTPNSLSQEVGLGLGAQAGEARLRKVFTEAGFSSFRRATETPF
                     NLILEARK"
     aSDomain        complement(2213..2530)
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_KUF73_RS02285_oMT.1"
                     /domain_subtypes="oMT"
                     /evalue="6.70E-12"
                     /label="KUF73_RS02285_oMT.1"
                     /locus_tag="KUF73_RS02285"
                     /protein_end="270"
                     /protein_start="164"
                     /score="36.1"
                     /tool="antismash"
                     /translation="KLEAGAKVADIGCGHGASTVIMAQAFPDSRFVGFDYHAPSVTVAT
                     QRAEEGGVSSRARFFQGTAKSYPGDDYDLVCYFDCLHDMGDPVGAAKHAYESLKPDGTV
                     LL"
     misc_feature    complement(3238..3251)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 17.57"
                     /tool="antismash"
     misc_feature    3240..3253
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 19.61"
                     /tool="antismash"
     misc_feature    3241..3254
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 17.75"
                     /tool="antismash"
     misc_feature    3242..3255
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 18.08"
                     /tool="antismash"
     misc_feature    complement(3245..3259)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 19.75"
                     /tool="antismash"
     gene            3522..4856
                     /locus_tag="KUF73_RS02290"
                     /old_locus_tag="KUF73_02290"
     CDS             3522..4856
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010455516.1"
                     /locus_tag="KUF73_RS02290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KUF73_02290"
                     /product="acetamidase/formamidase family protein"
                     /protein_id="WP_218436413.1"
                     /transl_table=11
                     /translation="MTTLVSQPNLNATPVNRLRVDHYTNGIIGPSQPMLGPLADGGTLI
                     TGTPPGCWGPMITPSFEGGHEVTQPVAIVGAEIGDAVAIKIKSMRVTSLATSSGVMTFV
                     EGRYNGDPFVSKFCAKCGTEHPASHVDGIGEDAIRCNNCGAEVSAFRFSHGYVIVFDAQ
                     NQVSLTVNQDIANQLAGNASQMSALPEFAAQHSILSLARADIPGVAAHMRPFLGNIGTM
                     PSRDIPDSHNCADFGQYLINAPHRFGMTREELHAAKTDGHMDTNSIREGCVLICPVKVP
                     GAGVYMGDMHAQQGNGEIAGHATDCSGETEVSVEVVKNLTLEGPILLQNLDDLPPMARP
                     MNAEQRAKVRELGARWGQHEIEQSGPITFIGSGENLNLAVENGLTRAATVTGLPYDEVL
                     NRATITGSIDISRLPGTVRVTFLCPMDVLDRIGIGHLVREKYDLA"
     gene            5001..5840
                     /locus_tag="KUF73_RS02295"
                     /old_locus_tag="KUF73_02295"
     CDS             5001..5840
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: DUF692"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007990964.1"
                     /locus_tag="KUF73_RS02295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KUF73_02295"
                     /product="DUF692 domain-containing protein"
                     /protein_id="WP_218436414.1"
                     /sec_met_domain="DUF692 (E-value: 4.1e-118, bitscore:
                     389.2, seeds: 7, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQTPITSAKASAGLGLRRGLMKDLLAASAGHFDFLEVAPENWIGI
                     GGAHGAALRTLAERYPLSCHGLSLSLGGPSPLDVGFLQEVRVFLDHHNVPLYSEHLSYC
                     SDDGHLYDLLPLPFTEEAVLHVAARIRQAQDILGRRLAVENVSYYAAPQQDMDEVTFTN
                     AVLREADCDLLLDVNNVYVNSINHGFDPRSFLAGIDSNRVVAMHIAGHFDESDTLKIDT
                     HGASVKPAVWSLLAEAYARFGAQPTLLERDFNFPAFSELVAELQTIRRLQTQEVTRG"
     gene            5869..6588
                     /locus_tag="KUF73_RS02300"
                     /old_locus_tag="KUF73_02300"
     CDS             5869..6588
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008013747.1"
                     /locus_tag="KUF73_RS02300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KUF73_02300"
                     /product="DUF2063 domain-containing protein"
                     /protein_id="WP_371135400.1"
                     /transl_table=11
                     /translation="MGQYLRNPDHCAPPAEMNPVRAEIYRDLVFANLSSLISGTFPVLV
                     KILGDARWRSLVRIFLRDYRAKTPKFGEIAEEFVEFLASDPAALADGSWPPFMVELAHY
                     EWVEMALQQSDDQPLPVSDAGLLLECPLQVSPLTWPLAYAWPVHLVGPDYQPDTAPAQP
                     TLLLVRRVEDWSVKFSELSPLAWRLLQRIEEFPELSGHAQLQELAVEAGRTGSQTFFDN
                     GLALLRQMHDEGVLGLV"
     gene            complement(6698..7642)
                     /locus_tag="KUF73_RS02305"
                     /old_locus_tag="KUF73_02305"
     CDS             complement(6698..7642)
                     /EC_number="2.7.7.41"
                     /GO_function="GO:0004605 - phosphatidate
                     cytidylyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0016024 - CDP-diacylglycerol biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007954358.1"
                     /locus_tag="KUF73_RS02305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KUF73_02305"
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="WP_218436416.1"
                     /transl_table=11
                     /translation="MSLEVKFLWFFAAIACLLAVASLVGRVLAKRATTESAISTIENLN
                     QRVNAWWGMVIIFFVSWLLGPNATVVLFGFISLFALREFITLTPTKPGDHNALFSAFFI
                     LIPLQYFLIGTHWYSMFTLLIPVYAFLLLPAIAVLSQDTEAFLERTAKIQWGVMICIYC
                     ISHAPALLLLDLEGFKGQNALLLFYLVFVVQMSDVLQYVFGKLFGRHKVAPLVSPSKTV
                     EGLVGGGLSATLIGGCMFWMTPFNFWQSLLMSLAIVVMGFLGGLVMSAIKRSLSAKDWG
                     TMIKGHGGMLDRMDSICFAAPIFFHLTRYFFSV"
     gene            complement(7639..8238)
                     /locus_tag="KUF73_RS02310"
                     /old_locus_tag="KUF73_02310"
     CDS             complement(7639..8238)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1141: acyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017338025.1"
                     /locus_tag="KUF73_RS02310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KUF73_02310"
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="WP_218436417.1"
                     /transl_table=11
                     /translation="MWISNALIAVLRLVIGVTARWESPPDLTRQRIYFANHTSHMDTLA
                     IIAALPPEARVNVKPVAAADYWGKNRFLSYISQQGLNAVLIERNPAPGTHVLEPIFDVV
                     RAGHSIIIFPEGTRSNQALPGEFKSGLYRLGESFPDVDLVPIYLENLHRSMPKGKHVPL
                     PIICTIRIGDPLPRIAGEDKQMFLERARDAIVRLSK"
     gene            complement(8225..8857)
                     /locus_tag="KUF73_RS02315"
                     /old_locus_tag="KUF73_02315"
     CDS             complement(8225..8857)
                     /EC_number="2.7.8.-"
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_function="GO:0000287 - magnesium ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA]"
                     /GO_process="GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008043298.1"
                     /locus_tag="KUF73_RS02315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KUF73_02315"
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="WP_218436418.1"
                     /transl_table=11
                     /translation="MDDNRRPIKARSSGWAKRITDTLVKKDVSPNQISVASIGFALAGA
                     LALIIDNGVLGSICCAVGIQLRLLCNLLDGMVAIEGGKKSDIGSLYNEFPDRIADSVLI
                     VGLGYAIGYADLGWFAALAAALTAYVRVFGGSIGLKQSFMGPMAKQHRMALMTAGVLLN
                     AVEVVVYATHYLLLLTLVVIAIGSAATCATRTLAISRQLKEAGHVDQ"
     gene            complement(8968..10290)
                     /locus_tag="KUF73_RS02320"
                     /old_locus_tag="KUF73_02320"
     CDS             complement(8968..10290)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008063064.1"
                     /locus_tag="KUF73_RS02320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KUF73_02320"
                     /product="ATP-binding protein"
                     /protein_id="WP_218436419.1"
                     /transl_table=11
                     /translation="MNLSMRWPRTLASRLSLIFLIGLILAQALSFGAQYYERYESAKDT
                     MLGNLETDVSTSIAILDRLPADERASWLQQLQRKNYGYLLSEGEKGAPMDMGMPDAPIA
                     MASIKDAIGKEYPMTFSDISGPNKHFQVHLKLSDGSPLTIDVRPAMVPLSPWLPIVLLG
                     QLALMLACTWLAVRIAIRPLTRLAEAVDTLDPNTHPVLLDENGPTEVAHAAKAFNAMQA
                     RIAAYLKERMQLLAAISHDLQTPITRMKLRAEFMDDCVEKDKLWNDLGEMEHLVREGVA
                     YARSIHGSTEESRRTDLDSFLDSLVFDYQDMGKDVQLNGKSAVVIDTRPHALRRVLVNL
                     TDNALKFAGAAELSVEAKADGYLSVKVMDRGPGIAEEELAQVMEPFYRVENSRNRSTGG
                     TGLGLAIAQQLALAIGGSLTLSNREGGGLCAELKLRGKAGQ"
ORIGIN
        1 tggccgtggc ccagagcctg agttttgccg tggcctgcga gcgcctgcac ctgtcgcagt
       61 cagccctgag cctgaccatc aaggcgctgg aagagggcct cggcggacgc ttgtttaccc
      121 gcaacacccg taatgtggcg ctgaccgccg aaggcgagtc gctggtgcca ctggcgcgcc
      181 gtctgatcgc cgactgggac aatgccgagg acgaactgcg ccagcgcttc actctgcagc
      241 gcgggcgggt gaccttggcg gccatgccat cgtttgccgg caacctgttg ccgccaatcc
      301 tcaagacgtt ccgtgcccgc tacccgaaag tcaacgtcac cgtgaacgac gtgatcaacg
      361 aacaggtgct ggaaatggtc cgtgaccgtc aggtggaact gggggtggcg tttgagccga
      421 ccatgagttc gtcgctgcaa ttcaccccct tgtatatcga tcgatttgtg gcggtggtgc
      481 ctgatgattc ggcactggcc gaactcgacg aaatcgattg gcagacgctg ctcaaggaac
      541 cgttcatcac cctgcagcgc ccgtcgacgg tgcgggtcat gctggaagaa catctgcagg
      601 cgcggggaat gaaattgccg gtggaatttg aaagccacca actggcgaca gtcgggcgga
      661 tggttgccag tgggttgggg gtgagtgctg tgccagcgtt gtgcgccggg cagatgcgtg
      721 aactgggcgc gcgatgcatc accttgagcg accctgtggt ggagcgggca atcggcgtgc
      781 tgaccctgcc gggcgcagaa ctgtcggcgg cggcccaggc attgtttgat gtgcttaaag
      841 cacaattttc tctctaacac cccaccccct gtaggagctg ccgcaggctg cgatcttttg
      901 atcttgatct tcagcgattt cagcaccgcc aaaaaaccag atcaaaagat cgcagcctgc
      961 ggcagctcct acagggtatt gagttgatta gttgaagagg cgttgagcca gcaacggtaa
     1021 aagttgttcg cacgaccctt ctattttcaa atccagaatg tcatccgcgc gggttttgcc
     1081 caggttgatc gccagcaacg gcttgccctg atccaccacc gcccggcaca ggcggaacgc
     1141 cgaatatgcc atcagcgacg aaccgaccac cagcaacccg gcagcctttt ccacggcggc
     1201 catcgctttg gctgccgttt cctgggcgac gttttcgcca aagaacacca cgtcgggttt
     1261 catccgttct ccggcgcaat gcgggcaatg cggcacttga aagcgtgctt caaaggccgc
     1321 gtccagcagg gtgtcgccgt ccggcgcctg caccgcgtca acgccggcca gataaggatt
     1381 ttgtgcttcc atcaggtgct ggatcgaatc tcgctcgctg cgttttccgc agtccaggca
     1441 cagcacccgg tgcaggctgc cgtgcagttc gatcacgtca tggctaccgg cctgatcgtg
     1501 cagggtgtcg acgttctggg taatcaaccc gctgatttgt cgggtgcttt gcaagcgggc
     1561 gagggtgtcg tgggcgacgt tcggttgggc ctggcgcacc cgtggccaac ccagcatcgc
     1621 ccgcgcccaa taacgccgcc gggactcggg tgccgagaga aattcctggt acatcatcgg
     1681 ctgccggcca cgacgtacgc cctggttatc gcggtagtcc ggaatacccg agggcgtgct
     1741 gatcccggca ccggtcagga ccacgaacgg tcgatcagcc ataagctgct ggagccggtc
     1801 gagctgttct cggatcgggt ggtcgagcat gttcaacact ccggtggacc ctgggtgcat
     1861 gcagattagc atcacccctg taggagctac cgaaggctgc gatcttttga ttttgctttt
     1921 aacggcaaga tcaaaagatc gcagccttcg gcagccccta cattttggcc gtcagttatt
     1981 tgcgtgcctc cagaatcagg ttgaacggcg tttccgtggc ccggcggaaa cttgaaaatc
     2041 cggcctcggt gaacactttg cgcaaccgcg cctcgcctgc ctgggcgccg aggccgaggc
     2101 cgacttcctg ggacagcgag ttgggcgtgc agatgaaggt cgaggcggca taaaacaatc
     2161 gaccgaccgg ggtgatgttg tcgtcgagcg agtcgttggc gaacggttct accagcagca
     2221 ccgtgccgtc tggtttcaac gactcatagg cgtgtttcgc cgcgcccacc gggtcaccca
     2281 tgtcgtgcag gcagtcgaag tagcagacca ggtcatagtc gtcgccgggg tagcttttgg
     2341 ctgtgccctg gaagaaccgc gcgcgactgg agacgccacc ttcttcagcg cgttgggtgg
     2401 cgacggtgac ggagggtgcg tggtagtcga aaccgacgaa ccgcgaatcc ggaaacgcct
     2461 gggccatgat caccgtggag gcgccatgcc cgcagccaat gtccgccact ttggcaccgg
     2521 cttccagctt ggcgaccaca ccatcaagcg ccggcagcca ttcggcgatc aaatgtgcct
     2581 tgtagccagg gcggaagaac cgttccgtgc cgctgaacat gcacggatgg tgatcacccc
     2641 agggcagggc accgtcgccg cgcatcgctt tgaccagttt gtccttgtca tggaaaaacg
     2701 acgcgaccac cccgataccg ccagcaatgt agaccggtga gtcttcgatg gccaatgcca
     2761 gggcctgctc ttcgggcagg cggaactggc cgtcaacgtg ttccatgtag ccggaggcgg
     2821 cgtgggcgct aagccattca cgcaccaggc gggggttgca gccggtcttg tcggcgagtg
     2881 tttcagggct ggtgggctgg ctgtcggcca tggcccggta caggccgagc tcttcgccaa
     2941 ggatgacgtt ggcgagcatc gccgcgccgc ccatgtcatt caccagtttg cccatgaaat
     3001 cgttgagtct ggcctcgtcc atcacgtgtg ctccttaaca ggatcacggt ccagaggcat
     3061 tgtttgtcga ggcatgcgcc tctgggcggt ggtcgttgga atgaacagga cgattggctc
     3121 gtcctgcgtg cattaagttt agttcgcggg ccgtgtgccg gtatctgagg cgacgaaagc
     3181 cccgcggttt ggcacagaac cctgtaggcg ctgccgaagg ctgcgatctt ttgatcttga
     3241 tctttaaaaa taaaaatcaa agatcgcagc cttcggcagc ccctacaggg tgcggtgcct
     3301 ggggagtgca tgtatcccaa tgtatctaac cgacctctcg atacagtccc ccacaactcc
     3361 ggaccatccg cgaacacaga ccagatacaa acctgcgatg aactgtgaag gccgttttgg
     3421 cgccttgaaa ccgtggcggc caagaccttt tcctgaccgc cttcaaaggc ggccttcgct
     3481 cctgactctg ttccgcgcct gatgcggtca aggggacaac aatgacaacg cttgtgtcgc
     3541 aacccaacct caatgccacg ccggtcaatc gcctgcgggt cgatcactac accaacggca
     3601 tcattggccc gagccagccg atgctcggtc cgttggctga cggcggcacc ctgattaccg
     3661 gaacgccgcc gggttgttgg ggcccgatga tcacgccatc gtttgaaggc ggccatgaag
     3721 tgacgcagcc ggtggccatc gtcggtgcgg aaatcggcga tgcggtcgcc atcaagatca
     3781 aaagcatgcg cgtgacctcg ttggccacct cgtccggggt catgaccttc gttgaagggc
     3841 gttacaacgg cgatccattc gtctccaagt tctgcgccaa gtgcggtact gaacacccgg
     3901 ccagtcatgt cgatggcatc ggtgaggacg cgattcgctg taacaactgc ggtgccgaag
     3961 tcagtgcgtt tcgtttcagc cacggctacg tgattgtgtt cgatgcacag aaccaggtca
     4021 gtctgacggt caatcaggac atcgccaatc aactggccgg caatgcctcg caaatgtcgg
     4081 cgctgccgga attcgccgcg cagcattcga tcctgtcgct ggcccgtgcg gatattcctg
     4141 gtgtggccgc gcacatgcgt ccgttcctcg gcaacatcgg caccatgcct tcacgcgata
     4201 tacccgattc ccacaactgc gccgatttcg gccaatacct gatcaacgcc ccgcaccgct
     4261 ttggcatgac ccgtgaagaa ctgcacgcag ccaagactga cggccacatg gacaccaact
     4321 cgatccgcga agggtgcgtg ttgatttgcc cggtgaaagt gccgggggct ggggtgtaca
     4381 tgggcgacat gcacgcccag cagggcaacg gcgagatcgc cgggcacgcc accgattgct
     4441 ccggggaaac cgaagtgagc gtcgaagtgg tgaaaaacct gacgctggaa gggccgatcc
     4501 tcctgcaaaa cctcgatgac ttgccgccta tggcccggcc catgaacgcc gaacaacggg
     4561 ccaaagtccg tgaattgggc gcacgctggg gtcagcacga gatcgagcaa agcggcccga
     4621 tcaccttcat cggcagtggc gaaaacctca acctggcggt ggagaacggc ttgacccgtg
     4681 ccgccaccgt taccggtctg ccctacgacg aagtactcaa ccgcgccacc atcaccggct
     4741 cgatcgacat cagccgcctg ccaggcactg tgcgcgtgac gttcctgtgc ccgatggacg
     4801 tgctggatcg tatcggcatc ggtcatctgg tgcgcgagaa gtacgacctg gcgtaatgcc
     4861 gaaaacaggg tctgtaccag agtgtgtaca gacccgctgg tgatacaagc cctgccgttt
     4921 tccgtcggta cgcaacacag ccccgataca tcacttcgat taactgtgat tccgtactga
     4981 caaccgttga gacagacacc atgcaaaccc ccatcacttc agccaaggcc agcgccgggc
     5041 tcggcttgcg tcgcggttta atgaaggatc tcctggctgc atcggccggt catttcgact
     5101 ttctggaagt cgcaccggag aactggatcg gcatcggcgg cgctcatggc gcagcgctgc
     5161 gaaccctggc cgagcgctat ccgttgtctt gtcacggctt gtcattgtcc ctgggtgggc
     5221 cgtcgccgct ggacgtcgga tttctgcaag aggtgcgggt ttttctcgat catcacaacg
     5281 tgccgctgta cagcgagcac ctgagttatt gcagcgatga tggtcacctc tacgacctgt
     5341 tgccgttgcc gtttaccgaa gaagcggtgc ttcacgttgc cgcgcgcatt cgtcaggccc
     5401 aggatattct cggtcgacgc ctggcggtgg aaaacgtctc ctactacgcc gcgccccagc
     5461 aggacatgga cgaagtgacg ttcaccaacg ccgtgctgcg cgaagcggat tgcgacctgt
     5521 tgctggacgt taacaacgtg tacgtcaact cgatcaacca tggtttcgat ccgcggtcct
     5581 ttctggccgg tatcgattcg aaccgtgtgg tggccatgca catcgccggg cacttcgatg
     5641 agtccgatac cttgaaaatc gacacccatg gcgcctcggt caaaccggcg gtgtggtcgc
     5701 tactcgccga ggcatatgcg cggttcggcg cgcaaccgac cttgctggag cgagacttca
     5761 actttccggc gttttccgaa ctggtggccg aattgcagac cattcgccgc ttgcagaccc
     5821 aggaggtgac ccgtggctaa gcgttcgctg cacgaacagc aacacagcat gggtcagtac
     5881 ctgcgcaacc ccgaccactg cgcgccaccg gccgaaatga acccggtacg agccgagatt
     5941 tatcgcgacc tggtgtttgc caacctgtcg tcgttgatca gcggcacctt tccggtgctg
     6001 gtaaagattc tgggcgatgc gcgctggcgt tcgctggtgc ggatattcct gcgcgactac
     6061 cgcgccaaaa cgccgaaatt tggtgagatc gccgaagagt tcgtcgaatt cctggcgtct
     6121 gacccggccg cgttggcgga tggatcgtgg ccgccgttca tggtggagct ggcgcactac
     6181 gaatgggtgg aaatggccct gcaacaatcc gatgaccagc cattgcctgt cagcgacgcc
     6241 gggttgttgc tggagtgtcc gttgcaggtc tcgccactga cctggccgtt ggcttacgcc
     6301 tggccggtgc atttggtcgg accggattac cagccggaca ccgcaccggc gcaacctacg
     6361 ttgctactgg ttcgccgggt cgaagactgg agtgtgaagt tttccgaatt gagcccgctg
     6421 gcgtggcggt tgttgcaacg aatcgaggaa tttcccgagc tgagcggcca tgcgcagttg
     6481 caggagttgg cggtggaggc ggggaggacc gggtcgcaga cgtttttcga taacgggttg
     6541 gcgctgttgc ggcagatgca tgacgaaggg gttttgggtt tggtgtgatc actacagtca
     6601 aaagatcgca gcctgcggca gctcttacaa atgcgatcct gcgcggttac acggccaatg
     6661 taggagctgc cgaaggctgc gatcttttga tcttcggtca aaccgagaaa aaataccgtg
     6721 tgaggtgaaa gaagattggc gccgcaaagc agatcgagtc catccggtcg agcatgccgc
     6781 cgtgcccctt gatcatggtg ccccagtcct tggcgctcaa gctgcgcttg atcgccgaca
     6841 tgaccaggcc accgagaaac cccatcacca cgatcgccag cgacatcaac agcgactgcc
     6901 agaagttgaa aggggtcatc cagaacatgc agccgccaat cagcgttgca gacagcccac
     6961 cacccaccag gccttcgacg gttttcgacg ggctcaccaa cggcgcgacc ttgtgtctgc
     7021 cgaagagctt gccgaacacg tactgcaaga catcgctcat ttgcacgacg aacaccagat
     7081 agaacagcag cagcgcgttc tggcccttga acccttcaag atcaagcagc aacagtgccg
     7141 gcgcgtggct gatgcaatag atgcagatca tcacccccca ctgaatcttt gccgttcttt
     7201 ccagaaacgc ctcggtgtcc tggctcaata ccgcaatcgc cggaagcagc aggaaggcat
     7261 ataccggaat cagcagcgtg aacatcgagt accaatgggt tccgatcagg aaatattgca
     7321 gcgggatcag gatgaaaaaa gccgaaaaca gcgcgttatg gtcacccggt ttggtgggtg
     7381 tcagggtgat gaattccctg agggcgaaca gcgagatgaa accgaacagg accactgtcg
     7441 cattcgggcc cagcaaccag gacacgaaga agataatgac catcccccac caggcattca
     7501 cgcgctgatt gagattttcg atggtcgaga tggcgctctc cgtcgtggcc cttttggcca
     7561 gcacccggcc gaccagcgaa gccaccgcca gcaggcaggc gatggcagca aagaaccaca
     7621 agaacttcac ttcaagactc atttcgacag cctcacaatc gcgtcgcgcg cgcgctccag
     7681 aaacatctgt ttgtcctcgc cggcaatcct tggcagcggg tcgccgatac ggatcgtgca
     7741 gatgatcggc aagggcacgt gcttgccctt gggcatcgag cgatgcaggt tttccaggta
     7801 gatgggcacc aggtcgacat cggggaagga ctcacccagc cgataaagcc ccgatttgaa
     7861 ctccccgggc aatgcctgat tggatcgagt gccttcgggg aagatgatga tcgaatggcc
     7921 ggcccgtacc acatcgaaaa ttggctccag cacatgggtg ccgggtgcgg gattgcgttc
     7981 aatcagaacc gcattgagcc cttgttgaga gatatacgag aggaacctgt tcttgcccca
     8041 gtaatcggcg gcggcgaccg gttttacatt gaccctggct tccgggggca gggccgcgat
     8101 gatcgccagg gtgtccatgt gactggtgtg attggcgaaa taaatgcgtt ggcgggtgag
     8161 gtcgggcgga ctttcccatc tggccgtgac gccgatcacc agccgaagca cggcaatcag
     8221 cgcgttactg atccacatgg ccggcctcct tcagttgcct ggagatcgcc agcgttcggg
     8281 tcgcacaggt ggcggctgag ccgatggcga tgacgaccag cgtcagcaac agcaaataat
     8341 gggtggcata aacgacaacc tcgacggcat tcaacagcac cccggcggtc atcaatgcca
     8401 tccggtgctg cttggccatc gggcccataa aactctgttt gagaccgata gagccgccaa
     8461 acacccgcac ataggccgtc agtgcggcgg ctagtgcagc aaaccagcca aggtctgcat
     8521 acccgatggc atagccgagc cctacgatca gcacgctgtc ggcaatacgg tcggggaatt
     8581 cgttgtagag gctgccgatg tccgacttct tcccgccctc gatggcaacc atgccgtcga
     8641 ggaggttgca cagcaggcgc agttgaatgc cgaccgcgca gcagatcgag ccgaggacgc
     8701 cgttatcgat aattagtgca agcgcaccgg ccagcgcaaa gccaatgctg gcgacggaga
     8761 tctggttggg ggaaacatct ttttttacca gcgtgtcggt gatccgtttc gcccaacctg
     8821 aagagcgcgc cttgatcggc cttctgttgt catccattgc ttggtgtccc tgtctcttgg
     8881 gtttcactaa gcgtatatgc aatttcaatg gattgatgtc agctgcttcc cacaatgcag
     8941 tgaccgatag tggaaagcga ctggacgtta ttggccggct ttcccgcgca atttaagctc
     9001 cgcacacaac ccaccaccct cgcgattact caacgtcaac gatcccccga tcgccaacgc
     9061 cagttgctgc gcgattgcca gacccaagcc ggtgccaccg gtgctgcggt tgcgcgaatt
     9121 ttccacgcgg tagaacggtt ccatgacctg cgccagttcc tcttcggcaa tgcccgggcc
     9181 acggtccatg actttcaccg acaggtagcc atcggccttc gcttcgaccg acaactcagc
     9241 ggcgccggcg aacttcaggg cgttgtccgt caggttgacc agcacccggc gcaaggcatg
     9301 gggacgggtg tcgatgacaa ccgcgctttt gccgttgagc tgaacgtctt tgcccatgtc
     9361 ctggtagtcg aacaccaggc tgtcgaggaa cgagtccaga tcggtgcggc gactttcttc
     9421 ggtagagcca tggatgctgc gcgcgtaggc cacgccttcg cgtaccaggt gttccatctc
     9481 gccgaggtcg ttccacagtt tgtctttttc gacgcagtcg tccatgaact cggcgcgcag
     9541 tttcatccgg gtgatcggcg tttgcaggtc gtgggagatg gccgccaaca attgcatgcg
     9601 ctctttgaga tacgccgcga tgcgcgcctg catggcattg aaggccttgg ccgcatgagc
     9661 gacttcggtc gggccatttt cgtccagcag cacggggtgg gtgttggggt cgagggtgtc
     9721 cacggcttcg gcgaggcggg tgagtgggcg gatggcgatg cgcacggcca gccaggtgca
     9781 ggcgagcatc agcgccagtt gcccgagcaa gacgatgggc aaccagggtg acaacggcac
     9841 cattgcaggc cgcacgtcga tggttagcgg gctgccgtcc gacagtttca ggtgcacctg
     9901 aaagtgcttg ttcggcccgg aaatgtcgct gaaggtcatc gggtattcct tgccgatggc
     9961 gtccttgatc gaggccatgg cgatcggcgc atcgggcatg cccatgtcca tgggcgcgcc
    10021 tttttcgccc tcactcaaca gatacccgta gtttttgcgc tgcagttgtt gcagccagct
    10081 cgcgcgttca tcggccggca agcggtcgag gatggcgatg gaggtcgata cgtcggtttc
    10141 caggttgccc agcatcgtgt ctttcgcgct ttcatagcgc tcgtaatact gcgcgccgaa
    10201 ggacagtgcc tgggcgagga tcaggccgat caagaaaatc agcgacaacc gcgaagccag
    10261 ggtacggggc caacgcatcg agagattcat gctggcgcac cgacgatttc gactggcaag
    10321 gagaacacat agccctcgct gcgcacggtc ttgatgtagg ccggttcacg ggcatcgtcc
    10381 agcaggcgct ggcgcaagcg gctcaccagc aagtcgatgg aacgatcaaa cagatcggcg
    10441 tcgcggccct gggtcaagtt gagcaactgg tcgcggttga gcacccgttg cgggtgatcg
    10501 aggaataccc gcaacaagcg atattccgca ccactgagag cgatcatggt gccgtcgcca
    10561 tcgagcaggt ggcgggccga cgtgtccagg cgccaccgcc cgaaagccag caggcggctg
    10621 gattcggtca ccaccaggtt cggcggcagc atccgtgtgc gccgtagcac agcgttgatt
    10681 cgtgccagca attcacgggc ggcgaatggc ttgaccaggt aatcgtcggc acccatttcc
    10741 aggccgatga tgcggtcggt ttcatcgttg cgggcggtga gcatcagtac cggtgtagcc
    10801 ttgtgtttgc cggaccgcag ctcgcggcag agcatcaggc
//
