LOCUS       NZ_CP075604            22982 bp    DNA     circular CON 12-SEP-2024
DEFINITION  Enterococcus faecalis strain 1207/14 chromosome, complete genome.
ACCESSION   NZ_CP075604
VERSION     NZ_CP075604.2
KEYWORDS    RefSeq.
SOURCE      Enterococcus faecalis
  ORGANISM  Enterococcus faecalis
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3264821)
  AUTHORS   Wardal,E., Sadowy,E., Zabicka,D. and Hryniewicz,W.
  TITLE     VanA Enterococcus faecalis in Poland
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 3264821)
  AUTHORS   Wardal,E., Sadowy,E., Zabicka,D. and Hryniewicz,W.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2021) Molecular Microbiology, National Medicines
            Institute, Chelmska 30/34, Warsaw 00-725, Poland
  REMARK    Nucleotide sequence updated by submitter
REFERENCE   3  (bases 1 to 3264821)
  AUTHORS   Wardal,E., Sadowy,E., Zabicka,D. and Hryniewicz,W.
  TITLE     Direct Submission
  JOURNAL   Submitted (21-MAY-2021) Molecular Microbiology, National Medicines
            Institute, Chelmska 30/34, Warsaw 00-725, Poland
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Unicycler v. 0.4.7
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 400.0x
            Sequencing Technology :: Oxford Nanopore MinION; Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_018986755.2-RS_2024_09_12
            Annotation Date                   :: 09/12/2024 05:12:56
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,549
            CDSs (total)                      :: 3,463
            Genes (coding)                    :: 3,375
            CDSs (with protein)               :: 3,375
            Genes (RNA)                       :: 86
            rRNAs                             :: 4, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 35 of 88
            Pseudo Genes (incomplete)         :: 43 of 88
            Pseudo Genes (internal stop)      :: 19 of 88
            Pseudo Genes (multiple problems)  :: 9 of 88
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 15:43:58
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 423331
            Orig. end                         :: 446313
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP075604.2.
            On Aug 11, 2021 this sequence version replaced NZ_CP075604.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from National Medicines
            Institute, Poland.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22982
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-ii"
                     /region_number="1"
                     /rules="cds(LANC_like and DUF4135)"
                     /tool="antismash"
     cand_cluster    1..22982
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22982
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12982](+)"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12982
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     misc_feature    846..862
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: medium, score: 21.28"
                     /tool="antismash"
     misc_feature    complement(2705..2716)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 18.15"
                     /tool="antismash"
     misc_feature    complement(3053..3066)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 18.44"
                     /tool="antismash"
     gene            3611..4006
                     /locus_tag="KKP64_RS17505"
     CDS             3611..4006
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="KKP64_RS17505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_233032318.1"
                     /transl_table=11
                     /translation="MSVAPSQLGQVIVLLDGKATHKAAVERNGTGSFIRLDNVLKAIPE
                     TINDLKNEQADIQLNVRQAKEQLEKPFEHEDELKVLLQRQTTLNLSIEMGEATLPETEK
                     SVVAPVLVKPKQLEDSQLQQETHNLSQ"
     gene            4100..4378
                     /locus_tag="KKP64_RS02100"
                     /old_locus_tag="KKP64_02105"
     CDS             4100..4378
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358248.1"
                     /locus_tag="KKP64_RS02100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KKP64_02105"
                     /product="hypothetical protein"
                     /protein_id="WP_216788134.1"
                     /transl_table=11
                     /translation="MSYKTSEAHRRASKKYRQENKETERINTYRRTARLYINKHSDIFD
                     LFQLQELLNKRFLTLLNDENLKDKDDLLKEYLSRQKEGLKKEDKEGD"
     gene            4380..4769
                     /locus_tag="KKP64_RS02105"
                     /old_locus_tag="KKP64_02110"
     CDS             4380..4769
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358249.1"
                     /locus_tag="KKP64_RS02105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KKP64_02110"
                     /product="hypothetical protein"
                     /protein_id="WP_002358476.1"
                     /transl_table=11
                     /translation="MFFIEYIFIWSEKIVDLLIGSLLKLVTWILQLIGQGFTYLIGQTS
                     PTSATHGALLFLAFVLVIGLGIIAVYLSPLLAVGLFIFLPLTLIALKYTLGWVVLFGIA
                     YFAYRMIKKLIHSIIYFFKAKEATE"
     gene            4787..5122
                     /locus_tag="KKP64_RS02110"
                     /old_locus_tag="KKP64_02115"
     CDS             4787..5122
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010717550.1"
                     /locus_tag="KKP64_RS02110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KKP64_02115"
                     /product="thioredoxin fold domain-containing protein"
                     /protein_id="WP_002358477.1"
                     /transl_table=11
                     /translation="MKQTVHAVLYTKPHCIQCKMSTKLMDELGLPYENTYYGNSEETNS
                     IEVDSQNDRKRSWSEQKVEKLKAKYGIHSLPLIKIIDDETEEELEYWAGFKPDRIKYWQ
                     AINVKDK"
     gene            5126..5539
                     /locus_tag="KKP64_RS02115"
                     /old_locus_tag="KKP64_02120"
     CDS             5126..5539
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358478.1"
                     /locus_tag="KKP64_RS02115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KKP64_02120"
                     /product="hypothetical protein"
                     /protein_id="WP_002358478.1"
                     /transl_table=11
                     /translation="MDKMIDFIEKCFAVGWTIFFGGFFVFVTVGMCRSVLDDRWILFFG
                     LVVLFLFFLGAFLFGLQKCISLFSIRKSTLKLKKAAHFISISAFLYMGIFYSVISITSP
                     KENVGKLAIFGWVAFVFTAVSYWHDYRQFKGKR"
     gene            5553..5699
                     /locus_tag="KKP64_RS02120"
                     /old_locus_tag="KKP64_02125"
     CDS             5553..5699
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010717552.1"
                     /locus_tag="KKP64_RS02120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KKP64_02125"
                     /product="hypothetical protein"
                     /protein_id="WP_010706732.1"
                     /transl_table=11
                     /translation="MENTNDRRANYKDSVKKRLTELEIGLRIQDKQIVKNYKMKKAKAK
                     RRD"
     gene            5707..6180
                     /gene="ssb"
                     /locus_tag="KKP64_RS02125"
                     /old_locus_tag="KKP64_02130"
     CDS             5707..6180
                     /GO_function="GO:0003697 - single-stranded DNA binding
                     [Evidence IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /GO_process="GO:0006281 - DNA repair [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /GO_process="GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="ssb"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002365876.1"
                     /locus_tag="KKP64_RS02125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KKP64_02130"
                     /product="single-stranded DNA-binding protein"
                     /protein_id="WP_002358253.1"
                     /transl_table=11
                     /translation="MINNVTLVGRLANDVDLRYTSSGIAVGQFRLAVNRNFTNQSGERE
                     ADFISCAIWRKAAESLANYARKGSLLGITGRIQTRNYDNQQGQRVYVTEVIVENFQLLE
                     SKEISEQRRANASTPVTNGQQANNQQQTPLPDPLDPFSKESSPVNISDDDLPF"
     gene            6213..6635
                     /locus_tag="KKP64_RS02130"
                     /old_locus_tag="KKP64_02135"
     CDS             6213..6635
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002404183.1"
                     /locus_tag="KKP64_RS02130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KKP64_02135"
                     /product="hypothetical protein"
                     /protein_id="WP_002358479.1"
                     /transl_table=11
                     /translation="MPKNYKIITLDFQEKTVKFNPLQAWRDALQADLEAKNYTTFVPEM
                     YFPDAPVDESIDLYTLNNKLVVLEPTKRLVMFRNMHFSIVFHQQTEDRLLLETNTLASG
                     IDAVLLANKFQEEKEIIQKHANYLLQIFVSEGNEDE"
     gene            6628..7017
                     /locus_tag="KKP64_RS02135"
                     /old_locus_tag="KKP64_02140"
     CDS             6628..7017
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002404182.1"
                     /locus_tag="KKP64_RS02135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KKP64_02140"
                     /product="hypothetical protein"
                     /protein_id="WP_010706731.1"
                     /transl_table=11
                     /translation="MNKKLLGLVSLAILTLLFLGGCGNKNLNEVLTDGTGKWELQSLDD
                     TSHSAKIAFFTTGKANFLSGNNEIELEYKVNEKNTEIELIRPNSTDSMVKLTSIKIIDN
                     KTIEAASQQGGSGDQEKVKLTKINN"
     gene            7123..8459
                     /locus_tag="KKP64_RS02140"
                     /old_locus_tag="KKP64_02145"
                     /pseudo=""
     CDS             7123..8459
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002404181.1"
                     /locus_tag="KKP64_RS02140"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="KKP64_02145"
                     /product="hypothetical protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MEKRDILILSSFVFVVMLIYNFGIKQMEFGDDAFFLKQFTHDFQS
                     NYYEFLKFRYNEWTSRLVIEIVLTQAVQHVFLWRVLNAIAMSIVAIVPALLINSDNRRR
                     GLIIGTGMSLLIPASMINNAGWIATTTNYVWVMAAALLSIWPIMNYIRGKSVNWLSFIL
                     SLVFLIYATNQEQMVVIMLVSLLVLAGILYLSKMNILITLPHIAIVIASLVFILTCKGN
                     AARNVQETKQWLPNFSSYSIFDKLQIEYSSTLKALFFEWSPLMLAFVLLILTAGLVKNG
                     TLVKKMISGIPLLTYLICTRFNTIIDQTYDIVSGKTYMSLVVLLTGLVFLYVIGIFGAS
                     NNPLEFLSVIFLLILGVGSRIMMGFSPTIWVSGSRTYYFTYVLIMMSGVYLISQLPENN
                     QSRTFT"
     gene            complement(8905..9105)
                     /gene="cylR2"
                     /locus_tag="KKP64_RS02145"
                     /old_locus_tag="KKP64_02150"
     CDS             complement(8905..9105)
                     /codon_start=1
                     /gene="cylR2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002370931.1"
                     /locus_tag="KKP64_RS02145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KKP64_02150"
                     /product="cytolysin regulator CylR2"
                     /protein_id="WP_002358483.1"
                     /transl_table=11
                     /translation="MIINNLKLIREKKKISQSELAALLEVSRQTINGIEKNKYNPSLQL
                     ALKIAYYLNTPLEDIFQWQPE"
     misc_feature    complement(9091..9106)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: medium, score: 24.29"
                     /tool="antismash"
     gene            9509..9715
                     /gene="cylL-L"
                     /locus_tag="KKP64_RS02150"
                     /old_locus_tag="KKP64_02155"
     CDS             9509..9715
                     /codon_start=1
                     /gene="cylL-L"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358485.1"
                     /locus_tag="KKP64_RS02150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KKP64_02155"
                     /product="lanthipeptide cytolysin subunit CylL-L"
                     /protein_id="WP_002358485.1"
                     /transl_table=11
                     /translation="MENLSVVPSFEELSVEEMEAIQGSGDVQAETTPVCAVAATAAASS
                     AACGWVGGGIFTGVTVVVSLKHC"
     CDS_motif       9509..9580
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MENLSVVPSFEELSVEEMEAIQGS"
                     /locus_tag="KKP64_RS02150_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       9581..9715
                     /prepeptide="core"
                     /locus_tag="KKP64_RS02150_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="2.00"
                     /molecular_weight="4019.5"
                     /monoisotopic_mass="4017.0"
                     /core_sequence="GDVQAETTPVCAVAATAAASSAACGWVGGGIFTGVTVVVSLKH
                     C"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MENLSVVPSFEELSVEEMEAIQGS"
                     /leader_location="[9508:9580](+)"
                     /alternative_weights="4037.6"
                     /alternative_weights="4055.6"
                     /alternative_weights="4073.6"
                     /alternative_weights="4091.6"
                     /alternative_weights="4109.6"
     gene            9749..9940
                     /gene="cylL-S"
                     /locus_tag="KKP64_RS02155"
                     /old_locus_tag="KKP64_02160"
     CDS             9749..9940
                     /codon_start=1
                     /gene="cylL-S"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358181.1"
                     /locus_tag="KKP64_RS02155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KKP64_02160"
                     /product="lanthipeptide cytolysin subunit CylL-S"
                     /protein_id="WP_002358181.1"
                     /transl_table=11
                     /translation="MLNKENQENYYSNKLELVGPSFEELSLEEMEAIQGSGDVQAETTP
                     ACFTIGLGVGALFSAKFC"
     CDS_motif       9749..9856
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MLNKENQENYYSNKLELVGPSFEELSLEEMEAIQGS"
                     /locus_tag="KKP64_RS02155_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       9857..9940
                     /prepeptide="core"
                     /locus_tag="KKP64_RS02155_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="2.00"
                     /molecular_weight="2632.0"
                     /monoisotopic_mass="2630.3"
                     /core_sequence="GDVQAETTPACFTIGLGVGALFSAKFC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MLNKENQENYYSNKLELVGPSFEELSLEEMEAIQGS"
                     /leader_location="[9748:9856](+)"
                     /alternative_weights="2650.0"
                     /alternative_weights="2668.0"
     gene            10001..12982
                     /locus_tag="KKP64_RS02160"
                     /old_locus_tag="KKP64_02165"
     CDS             10001..12982
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368286.1"
                     /locus_tag="KKP64_RS02160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KKP64_02165"
                     /product="type 2 lanthipeptide synthetase LanM family
                     protein"
                     /protein_id="WP_002358487.1"
                     /sec_met_domain="DUF4135 (E-value: 1.4e-93, bitscore:
                     311.6, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 8.8e-50, bitscore:
                     167.0, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEDNLINVLSINERCFLLKQSGNEKYDIKNLQAWKERKSVLKQDD
                     LDYLIKYKYESLDNFGLGITPIENFPDKEVAIQYIKDQSWYIFFESILDSYNDSEEQLL
                     EVDASYPFRYFLQYARLFLLDLNSELNICTKEFIINLLENLTQELIHLTSKTLVLDLHT
                     FKKNEPLKGNDSSKRFIYYLKKRFNSKKDIIAFYTCYPELMRITVVRMRYFLDNTKQML
                     IRVTEDLPSIQNCFNIQSSELNSISESQGDSHSRGNTVSTLTFSDGKKIVYKPKINSEN
                     KLSDFFEFLNKELEADIYTVKKVTRNTYFYEEYIDNIEINNTEEVKKYYERYGKLIGIA
                     FLFNVTDLHYENIIAHGEYPVIIDNETFFQQNIPIEFGNSATVDAKYKYLDSIMVTGLV
                     PYLAMKDKSDSKDEGVNLSALNFKEQSVPFKILKIKNTFTDEMRFEYQTHIMDTAKNTP
                     IMNNEKISFISYEKYIVTGMKSILMKAKDSKKKILAYINNNLQNLIVRNVIRPTQRYAD
                     MLEFSYHPNCFSNAIEREKVLHNMWAYPYKNKKVVHYEFSDLIDGDIPIFYNNISKTSL
                     IASDGYLVEDFYQESALNRCLNKINDLCDEDISIQTVWLEIALNIYNPYKYINDLKNQN
                     SNKYIYTGSELNSKIIQACQKIEKKIFKRAIFNKKTNTVNWIDIKLDQDWNVGILNNNM
                     YDGLPGIFVFYVALKYITKNHKYDYVIECIKNSIYTIPSEDILSAFFGKGSLIYPLLVD
                     YRLNNDINSLNVAVEIADMLIEKKSINNGELKNDWIHGHNSIIKVLLLLSEITEDEKYR
                     KFSLEIFEKLSEEPYFNFRGFGHGIYSYVHLLSKFNRIDKANSLLHKIKESYFEEEPKN
                     NSWCKGTVGELLATIELYDDNISNIDINKTIAYKNKDCLCHGNAGTLEGLIQLAKKDPE
                     TYQYKKNKLISYMLNDFEKNNTLKVAGSEYLESLGFFVGISGVGYELLRNLDSEIPNAL
                     LFEL"
     gene            12994..15138
                     /locus_tag="KKP64_RS02165"
                     /old_locus_tag="KKP64_02170"
     CDS             12994..15138
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002415198.1"
                     /locus_tag="KKP64_RS02165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KKP64_02170"
                     /product="peptidase domain-containing ABC transporter"
                     /protein_id="WP_002358488.1"
                     /sec_met_domain="Peptidase_C39 (E-value: 1.7e-41, bitscore:
                     138.7, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKRLKYVAQGEHSECALACITMLLNYYGNQSTLVELREKYGVPKG
                     GLTIKNIRTVFDEYGFDVSTFKSSFSNYLDLPTPVISYWNNQHFVVIEKIKKKKILILD
                     PASNKRWIDISEFKKNFSNILIYAHKKKTKKEGERKQFFLKSFIFTKFKRYFFSLIILS
                     FVSQLLLLLIPIATKYSIDNIRSFQEIPTYILLLILTSFFSVLYVVQYLKSSVVAEFQY
                     EFDFKLMFSYIDKLFSMPLMYFSNRSTGELVFRANLNIYIRQILSQKVITTLIDSLFLG
                     IYLFLMVNYSILLTIIALVLISLIAFLSIINSHTIKRFVDKEIMEQGNVQRIITEAIEG
                     IETIKSANAEKSFLLNWKNMFTSQLLITKNKNRYIAIFGILPEIIQSVMPALFLIIGIK
                     LIINNSLSLGSLIGFVSIVTMVMKPILSLVSSYNDFLLLNVYFQKLSEVLTYEEKNNFN
                     NKIGNVGKEEFIYRVNNVYYTISVFEKNILNGISFDIRKGDKVAIVGRSGSGKSTLLKL
                     LAGLLQPSNGEILYEGYPLSNNSNNRRNIFYVNQNAHIFNETIEKNISLEFKPNSSINE
                     KKRLKESMNKSKMDEVLLGIPQYEKTIVSENGSNFSGGQRQKIALARAFYSNVNTLLLD
                     EPTSAMDNISEFEVFSNLLDEKRTVITVAHRISTVKNFDKIILMDNGEIVCIGEHEDLI
                     ENSELYRSLYYKKQQFGGTK"
     gene            15135..16373
                     /locus_tag="KKP64_RS02170"
                     /old_locus_tag="KKP64_02175"
     CDS             15135..16373
                     /GO_function="GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S8"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1075: alkaline serine protease, subtilase family"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358184.1"
                     /locus_tag="KKP64_RS02170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KKP64_02175"
                     /product="S8 family serine peptidase"
                     /protein_id="WP_002404803.1"
                     /sec_met_domain="Peptidase_S8 (E-value: 5.4e-36, bitscore:
                     121.9, seeds: 43, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKRGFTYILISYIFLTLGTTGYASDLSNNISFFIDNSQTTAIEE
                     IESELSSEKVDYIQEIGLVSFKNLDDSDRKFIGKYFNVSEGKKLPDFKPEEVNSSILNI
                     NILNKDFKSFNWPYKKILSHIDPVKEQLGKDITIALIDSGIDRLHPNLQDNNLRLKNYV
                     NDIELDEYGHGTQVAGVIDTIAPRVNLNSYKVMDGTDGNSINMLKAIVDATNDQVDIIN
                     VSLGSYKNMEIDDERFTVEAFRKVVNYARKNNILIVASAGNESRDISTGNEKHIPGGLE
                     SVITVGATKKSGDIADYSNYGSNVSIYGPAGGYGDNYKITGQIDAREMMMTYYPTSLVS
                     PLGKAADFPDGYTLSFGTSLATPEVSAALAAIMSKNVDNFKDSNEVLNTLFENADSFID
                     KNSMLKYKEVRIK"
     gene            16374..17357
                     /locus_tag="KKP64_RS17510"
     CDS             16374..17357
                     /GO_function="GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358185.1"
                     /locus_tag="KKP64_RS17510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="site-2 protease family protein"
                     /protein_id="WP_002368282.1"
                     /transl_table=11
                     /translation="MKFISPMIFTLLLVIFTLVFELNLVSTAYFSLLLSIFVHELGHLV
                     FGLFNKVRPESLIFGFIKLSWEKQFKVRLNTQWGFFGGLFRYKPTTFNNKKILRLLTGG
                     PIFSLFFTLTFFVKIEFFQYFSLFNFSIFLITAVPFNFNGFMNDGYNIYKLVTKDYIFE
                     MYYIVSNSLLNKYNQSTFLNSNEVCKIIKKNKELPLYVLNTFLLYVIYEYLIDKNNRKL
                     KLIYPILSKEDKILNNKSYLQNFYLANLYMIEYILSVDNKQTFKKINLKILDSISRSRI
                     KYLNFKCSKSADDEISQSMTEFSNIIKNYSDQTSTMIIAEKQWVQN"
     gene            17890..19548
                     /locus_tag="KKP64_RS02180"
                     /old_locus_tag="KKP64_02185"
     CDS             17890..19548
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002404684.1"
                     /locus_tag="KKP64_RS02180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KKP64_02185"
                     /product="DNA/RNA helicase domain-containing protein"
                     /protein_id="WP_002404684.1"
                     /transl_table=11
                     /translation="MDIMNTTKDDQLINSMLRLCDDSIVHNPEQFFRKKELQNLYQFSE
                     KLLPVLTNIPKADNYFIGHSVSIGITRQFDVLRFSAKKVVNIELKDCMPSKGLEAIKSQ
                     LIKNQFFLKVLGKEIISCTYVADIEKIYTLTADDELNVLEFERLGELIPLDSLDVNELE
                     SQQLTNFIISPYSETDRFVSHTYFLTDQQLTKKYEIIQSNSKKIGVIGGAGTGKSILLF
                     DLAQTWVKEGKKVLVIFVGQLNNYMSISEKFGFEIVPIRLMNRKEILEGAYDIVIVDEA
                     QRLMTDQYEFLIKLETKIILSVDRSQTLHPSEADRNIEGEIEVNPNFKVVKLGEKIRTD
                     KELADFISKLMNLSARNISPHDYNNISINYFESREVAKDFIDNKVAHDCWISIEFTEYV
                     TQFTGTKKKSMISNRSLSAHEVVGKEYDKVIIVIDNLVRRGRDGKLIYLSGEEWYPYLE
                     MRLLLEALTRVRSKLMLVVVNNADMYVDIQRNLLSWKNDQLAGIKTYDKELNYDGWDNA
                     IGNLEIHVNGIMYKASKVEYIEKTRKVKVSYFAVE"
     gene            19693..20313
                     /locus_tag="KKP64_RS02185"
                     /old_locus_tag="KKP64_02190"
     CDS             19693..20313
                     /GO_function="GO:0000150 - DNA strand exchange activity
                     [Evidence IEA]"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367722.1"
                     /locus_tag="KKP64_RS02185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KKP64_02190"
                     /product="recombinase family protein"
                     /protein_id="WP_002404683.1"
                     /transl_table=11
                     /translation="MFRKGEEILPIYGYSRVSTSNQDYKTQIQKLEKAGAEKIFSEKYT
                     GTKKEGRKELEELLSIVKHGDKVLVTKIDRLARSIVDLNSIISSLNHSGVTITFLDNAL
                     TFEPNKSDSMQTLMMNMLGSFAQFERDLIVTRTQEGKQWHRANNKNYREGRPKRVLNDK
                     YKHALELMETNSMREVERKTGISLSTLKRIKKQAKEEQLLNEK"
     gene            20456..21181
                     /locus_tag="KKP64_RS02190"
                     /old_locus_tag="KKP64_02195"
     CDS             20456..21181
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010784116.1"
                     /locus_tag="KKP64_RS02190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KKP64_02195"
                     /product="hypothetical protein"
                     /protein_id="WP_002358492.1"
                     /transl_table=11
                     /translation="MSESVGIILGAVIALFGTIVTNYFTMKKTRLQEEKNSDRFLKKLK
                     AEEEIELKTFEHNIVMNNREHIPNAARDIVVEINQLFDSTEELVFNYPGTGYTGERPSI
                     LFSSTIDHLITGFPNSMEDIKELSNTWYHSNKKFKNVIFENSMFFPTELMNEIWEYEKY
                     CSDIKDYFYGRYSSIKSEEEFSAKKNEYQEQVDKYVFIQKDGIASYTHSVLSIYNTVKK
                     SRSDLVNKINTYQKQKTGF"
     gene            21226..21393
                     /locus_tag="KKP64_RS02195"
                     /old_locus_tag="KKP64_02200"
     CDS             21226..21393
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358494.1"
                     /locus_tag="KKP64_RS02195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KKP64_02200"
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="WP_002358494.1"
                     /transl_table=11
                     /translation="MATIRIDDELKHNADKMFDEVGINTLIAGEMFLNRFVKTGKFPFD
                     IEIIFYQPNT"
     gene            complement(21755..21877)
                     /locus_tag="KKP64_RS17515"
     CDS             complement(21755..21877)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="KKP64_RS17515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_256332644.1"
                     /transl_table=11
                     /translation="MIRPHVDRLKRWQELKVKNRPVSLAKDYDGLFFVVFIADF"
     gene            21981..22181
                     /locus_tag="KKP64_RS02200"
                     /old_locus_tag="KKP64_02205"
     CDS             21981..22181
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002362428.1"
                     /locus_tag="KKP64_RS02200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KKP64_02205"
                     /product="hypothetical protein"
                     /protein_id="WP_002404680.1"
                     /transl_table=11
                     /translation="MNFGYLNFGIKDAILAIVIFIILLLTILFHWSALEFVFSLGAVVI
                     AFFAGNMKQDKRVVEKQNKKK"
     misc_feature    complement(22846..22864)
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: medium, score: 26.64"
                     /tool="antismash"
ORIGIN
        1 accaatgtcc cttcaggaat tacaagagaa gatggtagcg ttcagccacc gatgactatg
       61 aacaattatt tccataaaca tatgctgacg catacgttgg gtaggtatca tttcaaaaac
      121 tatcgaggag gaacgtatac gcttaatcca agagaagaaa aaccttggca gacagaatta
      181 ccaaaggttt taaacacgat ggacggtcaa tttctctctg caaaaacaat gaaattatcc
      241 ttaccagagg tattgccgac tgtagaagaa caaaaagaag ctactattga ttcaaatatt
      301 cttaaattta gctttggtga gaaaaatggt gaaatttatt atcacggtct tgatggagta
      361 aaaaaacagg aattaaaatc aacacagaaa aaaaggttgc agcaaatgat tcagcttcgc
      421 gatcttgttt ctgaggtgat tgattatcaa caagacttgg attttgaatc gtcgatcttt
      481 gaagaaaaac tccaccgtct aaatgaatct tatgataaat tcgaacggaa gtatggctat
      541 ctaaacaatt caaccaatac tcgtttgttt tatgaggatg atcgatttgc acttttaatg
      601 tccattgaag tgccgcaaaa agatggttct tataccaagt ctgccatttt ccgagaagca
      661 acgattcgtc caattgaacc tgttataagc gtacactctg ctttagaagc actcaatcat
      721 agtttagcta aacaagggaa agtagatatt ccttatatga ccaaactcta caatgttcct
      781 gaaacacagc tgctagaaga attgaaaggg catatatttg ttgatgtaga gaaatatatc
      841 gaaaatgatg aaaagctagc caacagttat gtaacaaaag aagcctttct ttcaggagat
      901 gtgaagaaga aattaacctt atcaaaagcg ctggcaaaga aaaattctct ttttgaagag
      961 aatgtaaaag ccttaaaacc tgttattcct aaagacttag gtattgaaga catttcttac
     1021 gagcttggag caagttggct cccactagaa atctatcatg acttcatgga agaacggttt
     1081 cagttacctc cgttttatat taataaccaa caagtagcaa tagaatacaa tgagtttaca
     1141 gacacatatc atgtaaaagg aaaatccgct caccgttcta ttctggttac taatgaatat
     1201 ggaacggaac gagcaaatgc gtatcaattg ttagaaaaat ctttgaattt taaaacaatt
     1261 tctgtttatg atcaagtaga aaaagatgtc aatggtgaaa ggaaaaaagt ttctgtttta
     1321 aatgttgatg aaaccatgtt ggcacgaaca aaacaagatc gactaaaaaa agaatttaaa
     1381 ttatgggttt tttcagaccc taaacgtgcg caaagacttt tatctattta caatgaacga
     1441 tttaatcgga tacgtccacg aacctataac ggtgaacatt tgctttttga gggattgaat
     1501 cagcagttta cattacgacc tcatcaaaaa aatgttgtgg cgcgaattgt tgaaacagga
     1561 cgtactttga tggcgcatga agtaggtgca ggaaaaactg caagtatgat tgctgctgga
     1621 atgatgatga aagaccaggg gttgatcaaa aaaccaatgt attgtgtccc taatcattta
     1681 acagagcaat tcgggcaaga actcttgcgt ttttatccct ctaaaaaggt cttaatcact
     1741 acaaaaaaag attttgaaaa gaaaaatcga caaaaattta tttctcgtat agctacaggt
     1801 gaatacgatg ctgtcattat cggacatagt caaatggaaa agattccttt aagcaaagaa
     1861 cgtagagaat cactaattaa acgagaatta tccgaggttc gtcaaggaat taaagaatca
     1921 aaagcacaag caggtgaaag ttggagttta aagcaaatgg ttagttttga aaaacgacta
     1981 aaagaaaagt tagaagcttt gcaaaatgaa gaatataaag atcacttgct tacgtttgaa
     2041 gaattaggag tagatttctt atttgttgat gaagcacatg catacaaaaa cctttatacg
     2101 tatacaaaaa tgtccaatgt agcaggtgta aatacgtcaa atagtctacg tgcgagtgat
     2161 atgtatataa agtgccaata tttactagaa aagaatcatg gacgtggtgt cgtatttgcg
     2221 acaggtacgc ctatttccaa ttcaatgagt gaattgtata ccttacaacg gtttttacaa
     2281 cctgacgagt tagcgcgcat gcggttaacg acgtttgacc gttgggcgtc cacttttggt
     2341 gaagtagtaa gcgcacctga aataaaccca gagggaacga gcttccgaat gaaaaatcgg
     2401 tttgcgaaat ttcacaatct tcctgaatta atgcgatcct ttcaattagt ggcagatatt
     2461 caaacaagtg aacagttagc gttaccagtg cctgctattc aaacaggaaa accccaactt
     2521 attgtttctg atccaagtcc ttatcaagaa gaaaagatga ttgaactggg aaaacgtgca
     2581 gacgcaatta ggcaaaaatc ggttgaaccg catgaagata atatgttgaa aattactcac
     2641 gaagccaagt taatggcaat tgatccacgc ttattagacc caaccgttcc tgcttatcca
     2701 gaaggaaaac tatttcggtg cgtagataat gtctatcgta tttggaaaac atcggatctt
     2761 caacattcta cacaaataat tttttctgat agtgggacac caaaatcaaa tcaatttaat
     2821 gtttacgatg aagtaaaaca actgttaata aaaaaaggaa tccctgaaaa agagattgcg
     2881 tttattcatt ctgcaaaaaa tgaccgtcaa cgagaagaat tattcgaaaa agtccgtcaa
     2941 ggagaaattc gtattctctt aggaagtacc gaaaaattgg ggacaggcac gaatattcaa
     3001 gataagttgc tcgctgtcca ccatgtggat gtcccttggc gaccaagtga cttaacacag
     3061 cgtgatggac gaattgttcg tcagggtaat gaaaataaag aagttcagat ttatcgttat
     3121 gttgcaaaaa atagttttga ttcttttttg tggcaaacac aagaaaacaa actcaaattt
     3181 atcaatcaaa tcatgacaaa caaaagtatt gcacgttctg ctgaagatat tgaccagacg
     3241 atgatgtctg ctgctgaagc aaaatcaatt gctaccaata atccattgtt attagaaaaa
     3301 ttaacattag ataaaaaagt gatggagtat cagcttttac aaagtagttg gcaatcttca
     3361 cgcatttctt tattggaaaa agtggaaaca cgttacccaa aacgtttaga ggaaattcga
     3421 caaactttag aattatacga agaagatcgt caattggttg ctgaagaact aagtaaagag
     3481 ttttcaattg agttacaagg gacaatttac acagagaaaa aagaagcctt agacgtattc
     3541 aatcaactat tgcctgcacc aactgatggg acacaaaaaa aaagaaatcg ggcggtatcg
     3601 cggactatcc ttgtctgttg ctccttcaca attgggccaa gtcattgttc ttcttgatgg
     3661 aaaagcaact cacaaagcag cagttgaacg caatggaaca ggttctttta ttcgattaga
     3721 caatgtatta aaggcaatcc ctgaaacaat caacgatcta aaaaatgaac aagcagatat
     3781 tcaattaaat gtaagacaag cgaaggaaca gttagaaaaa ccatttgaac acgaagatga
     3841 attaaaagtg ttgttacaac gtcaaaccac tttaaattta tcgattgaaa tgggggaagc
     3901 gacattaccc gaaacagaaa aaagtgttgt agcgcctgtg ttggtaaaac ctaaacaatt
     3961 agaagatagt caattgcagc aagaaacgca caacttatcc caataataga ataaaacatg
     4021 tcctttttat aggtattgct tgatagatac acgtatacgt gttatcgttt agttgtacta
     4081 aaagaaagga cgtgtttttt tgagttataa aacaagtgaa gcacacagac gtgcaagtaa
     4141 aaaatatcgt caagaaaata aagaaacgga acgtataaac acgtatcggc gtactgcgcg
     4201 tttatatatc aataagcatt cggatatttt tgatcttttt cagctgcaag aactattaaa
     4261 taaacgcttt ttaacattgc ttaacgatga aaacctaaag gataaagatg atctgttaaa
     4321 agaatatcta tctcgtcaga aggaaggtct aaaaaaagaa gataaggaag gtgattaata
     4381 tgttttttat tgagtatatt tttatctggt cggagaaaat tgtagattta cttattggtt
     4441 cattattgaa gctagttact tggattctac aattaattgg acagggtttt acctacttga
     4501 tagggcagac aagccctact tcagccacac atggtgcgct actattttta gcttttgttt
     4561 tagtcattgg tttaggtata atcgctgttt acctgtcacc gttgttagca gtgggattgt
     4621 ttattttttt accacttacg ttaatcgctt taaaatatac gttaggatgg gtcgttttat
     4681 tcggaattgc ttactttgcg tatcggatga taaaaaaact cattcattct atcatttatt
     4741 tttttaaggc aaaagaagca acagaataat tactggagga gattttatga aacaaacagt
     4801 acatgcggtt ttatatacaa aaccacattg cattcaatgt aaaatgagca ccaaactgat
     4861 ggacgaatta ggattaccct atgaaaatac gtactatggt aattcagaag aaacaaactc
     4921 aattgaagtg gatagtcaga atgatcgtaa aagatcatgg agtgaacaga aagtagaaaa
     4981 gctaaaagca aagtatggta ttcatagttt gccactgatt aaaatcattg atgatgaaac
     5041 agaagaagag ttagaatatt gggcaggatt caagccagat cgtattaaat attggcaggc
     5101 tataaatgta aaggacaagt aatcgatgga taaaatgata gatttcattg agaaatgttt
     5161 tgcggtaggt tggacaattt tttttggtgg attttttgta tttgtgacag ttggtatgtg
     5221 taggtctgta cttgatgata ggtggatatt attttttggc ttagtagttt tatttctatt
     5281 tttcttaggt gctttcttgt ttggattgca aaaatgtatt tcattatttt ccatcaggaa
     5341 aagtacactg aaattaaaga aagctgcaca ctttattagt ataagtgcat tcttgtacat
     5401 gggcattttt tacagtgtga tttcgatcac gagtccaaaa gaaaatgtag gaaagttagc
     5461 aatttttggt tgggttgcct ttgtttttac agctgtttca tattggcatg actatagaca
     5521 atttaaagga aaaagataac atggagaata aaatggaaaa tacaaatgac agaagggcca
     5581 attataagga tagtgttaaa aagagactca ctgaactaga aattggcctt agaatacaag
     5641 ataaacaaat tgtaaaaaac tataaaatga aaaaagctaa agcaaaaaga agggattgaa
     5701 cgaaaaatga ttaataatgt tacgttagtt gggcgtttag ctaatgatgt ggatttaagg
     5761 tatacatcaa gtgggattgc agttggacaa tttcgtttag cagtcaatcg gaattttacc
     5821 aatcaatctg gggagcgaga agcggatttt attagttgtg cgatatggcg caaagcggca
     5881 gaatcgcttg ctaattacgc acgtaaaggt agcttacttg gaattactgg tcgtattcag
     5941 acgcgaaact atgataacca gcaaggacaa cgtgtttatg tgacagaagt gattgtagaa
     6001 aattttcaat tgttagaatc caaagaaata agcgaacaac gtcgggcgaa tgcttctacg
     6061 cctgtaacca atgggcagca ggctaataac caacaacaga caccacttcc tgatccgctt
     6121 gatcctttct caaaggagtc tagcccagta aatatttcgg atgatgattt gccattctaa
     6181 gtgtttttca atcaacgaaa ggattgattt ctatgcctaa aaattacaag ataattactt
     6241 tagattttca agaaaagact gttaagttta atccattaca agcgtggaga gatgctttac
     6301 aggcagattt agaagcaaag aactatacga cgtttgtgcc agaaatgtat ttccccgacg
     6361 caccagtcga tgagtccatt gatttatata cacttaataa taaactggtt gttttggagc
     6421 caaccaaacg actcgtgatg tttcggaata tgcacttttc gattgtcttt caccaacaga
     6481 cagaggatcg attgttgtta gaaactaaca ctttggcgtc tggtattgat gcggttttat
     6541 tagccaataa gtttcaagaa gagaaagaga ttattcagaa gcatgctaac tatctactac
     6601 aaatatttgt atcggaggga aatgaagatg aataaaaaat tactaggatt ggtatcatta
     6661 gctattctga cccttttatt tttaggtggg tgtggaaata agaacttgaa tgaagttctg
     6721 actgacggaa caggtaaatg ggaattacag tctttagatg acacgtctca ttctgcaaaa
     6781 atagcttttt ttactacagg aaaagcaaac tttttatctg gaaacaatga gattgaatta
     6841 gagtataagg ttaatgagaa aaatacagaa attgaattaa ttcggcctaa ttctacggat
     6901 tcgatggtta agctaactag tattaaaatc attgacaata agacaattga agcagcaagt
     6961 cagcaagggg gatcggggga tcaagaaaaa gttaagttaa caaaaataaa taactaagaa
     7021 tgagctctac acttatgatt ataagctgta aagcctaata ttctttagaa aaatatgtac
     7081 ttggaataaa tataggattg gagagaacta gtgacaggta aaatggaaaa gagagatatt
     7141 ttaattctca gtagttttgt ttttgtggta atgttaattt acaattttgg tattaaacaa
     7201 atggaatttg gggacgatgc gtttttctta aagcagttta cacatgattt tcaaagtaac
     7261 tattatgaat ttttgaagtt taggtacaat gaatggacgt ctcgattagt gattgaaata
     7321 gttctaacac aagcggtaca acacgtattt ttgtggagag ttttaaatgc tatagcaatg
     7381 tctatagtgg caattgtccc tgcactactg attaactcag ataataggcg aagaggatta
     7441 attataggta ctggcatgtc attattaatt cctgcttcga tgataaataa tgcaggatgg
     7501 atagcaacaa caacaaatta tgtttgggtc atggcagcag cgttgttaag tatttggcct
     7561 attatgaact atataagagg aaaaagtgta aattggctat cctttatttt atcgttggtt
     7621 ttcttgattt atgctacaaa ccaagaacaa atggtagtta ttatgttagt ttctttatta
     7681 gttttggcag gtattctgta tttatctaaa atgaatatct tgataacttt acctcatatt
     7741 gctattgtaa tcgctagcct tgtgtttatt ttaacatgta aggggaatgc ggcaagaaac
     7801 gtccaagaaa cgaaacaatg gttacctaat ttttctagct acagtatttt tgataagtta
     7861 caaatagagt attcgtccac tttgaaagct ttattttttg agtggtctcc attgatgtta
     7921 gcttttgtat tgctaattct tactgctgga ctagtaaaaa atgggacatt agtcaaaaag
     7981 atgattagtg gaataccgct attgacgtat ttgatttgta caagatttaa tacgattatt
     8041 gatcaaactt atgatatagt ttcaggaaaa acatatatgt cactagtagt tcttcttact
     8101 gggttggttt ttctttatgt aatagggatt tttggggcaa gtaataatcc cttagaattt
     8161 ttatcagtta tctttcttct tattttgggt gtaggaagtc gtattatgat ggggttctct
     8221 cctaccatat gggtatctgg atcaaggact tactatttca cttatgttct tataatgatg
     8281 tcaggtgtct atttaataag tcagctacct gaaaataacc aaagtagaac ctttacctga
     8341 aaataaccaa agtagaacct ttacctgaaa ataaccaaag tagaaccttt aaagtgctat
     8401 tcggatattt tctggtattg gctctattat taataatgat gtatacaaaa atattgtaaa
     8461 atgttttgct aaactttcga cagttgttga aaggacagtg tgtatactgt tgaataatta
     8521 caagtcactt cagatttaac tattttctta cagactgaat taatcaatca tttagttcta
     8581 tgagtatgcg ttagaaatga aaggctaaaa taagttataa ccttagagac tgtctccccc
     8641 caaaaagaga tagtctttac tatacatttg agcctagttt ttatttaaat gaatgtaatc
     8701 ataagtgagg gttttactga taaaaaatca gttatgatta aagtataaaa caacagtcat
     8761 aattatttat gctttaaaat ataaactgtt actatgccaa caattattcc taaaaataaa
     8821 atcagaaggg atataaactt tttcttcata cgaagcacct ttcttttaat ttaaatattc
     8881 tgtggtgaaa tttaaaaatc ttttttattc aggttgccat tgaaaaatat cttctagtgg
     8941 agtattcagg tagtaagcaa tttttaatgc taactgtaaa gaagggttat atttattttt
     9001 ttctatacca ttaatagttt gtctgctaac ttctaataaa gcagctaatt cactttggct
     9061 aatttttttt ttctctctaa ttaattttaa gttattgatt atcatttatg aagtcctctt
     9121 gttgaaaaaa agtagtaaca gagagtgcaa tatcattgat agagagaagt aatagtagat
     9181 aaaattaaag agatagtttt tagtaataac attaggtaga aaaagaaaaa tagcaactac
     9241 tataagtatg gaaaagttaa taaataagta catgtaagta gatgttaagg aaattgtata
     9301 taaaattcgc tcatcttttt ttgaatcagt cagattaaaa acaaagtaga ctacagaaat
     9361 gatatccaat aaaaaaataa aaatagccat tttggttcct cctttttgtc aagtatcact
     9421 tgacaaaaga ttaaaagctc tataatatta aattgtaaca tattatgtta tgcaatatac
     9481 aacaatttta tgatggaggg taagaattat ggaaaattta agtgtagttc ctagttttga
     9541 agaactaagt gttgaggaaa tggaagcgat tcaaggtagt ggagatgttc aggctgagac
     9601 aacaccggtg tgtgctgttg cggcgacagc tgcagcaagt agtgctgctt gtggttgggt
     9661 tggtggcggt atttttactg gagtaactgt agttgtgtct ttaaaacatt gttaaaatat
     9721 actataaaac ttagtgaggt gaagcacagt gctaaataag gaaaatcaag aaaactatta
     9781 ctctaataaa ttagaacttg ttggtccttc ttttgaagag ttaagtttag aagaaatgga
     9841 agcgattcaa ggtagtggag atgttcaggc tgagactact ccagcatgtt ttaccatagg
     9901 cttaggagta ggtgcattat tttcagctaa attttgctaa tttatatatt aagagggcta
     9961 gtttcactag ccctcttata cataaaaaag gagtgcttac atggaagata atctaataaa
    10021 tgtattaagc ataaatgaaa gatgtttttt actaaagcaa agtggtaacg agaagtacga
    10081 cattaaaaat ttacaagctt ggaaagaaag aaaaagtgtt cttaaacaag atgatttaga
    10141 ctacttgatt aaatataaat atgaatcact ggataatttt ggattaggaa taacacctat
    10201 tgaaaacttt cctgataaag aagttgcaat tcaatacatt aaagatcaat catggtatat
    10261 tttttttgaa tccattttag attcttataa tgatagtgaa gagcaattat tagaagtaga
    10321 tgctagttat ccttttagat atttcttaca atatgctcgt ttatttttac ttgatttaaa
    10381 ctcagagtta aatatttgta caaaagaatt cattattaat ttattagaaa atctaacaca
    10441 agagcttatt cacttgacaa gtaaaacatt agtgctagat ttgcatactt ttaaaaaaaa
    10501 tgaacctcta aagggaaatg atagtagcaa gcgatttatc tattatctaa aaaaaagatt
    10561 taactctaaa aaagatataa tagcttttta tacatgctat cctgagttga tgcgtattac
    10621 tgttgttaga atgagatatt ttttagataa tactaaacaa atgcttataa gagtgactga
    10681 agatttacct agcatacaaa attgttttaa catacaatcc tcagagctta actctatatc
    10741 agaatcacag ggagactctc atagtcgcgg aaatactgtt tctacactaa ctttttctga
    10801 tggaaagaag atagtataca agccaaagat taatagcgag aataaattaa gcgatttttt
    10861 tgaattttta aataaagaat tagaggcaga tatttataca gttaaaaaag ttactagaaa
    10921 tacctatttc tatgaagaat atatagataa tatagaaata aataacacag aagaagtaaa
    10981 aaaatattat gaaaggtatg gtaaactaat cggaatagct ttcttattta atgtaacaga
    11041 cttacactat gagaatataa tcgctcatgg agaataccct gttatcatag ataacgaaac
    11101 tttttttcaa caaaatattc ctatagagtt tggtaatagc gcaacagtag atgctaaata
    11161 taaatattta gattctataa tggtgacagg gctagtacca tatttagcga tgaaagataa
    11221 gtcagattcg aaagatgaag gggttaacct tagtgcgtta aactttaaag agcaaagcgt
    11281 accgttcaag atattaaaaa ttaaaaatac atttactgat gaaatgcgtt ttgaatatca
    11341 aacacacatt atggatactg caaaaaatac tccaattatg aataatgaaa aaattagttt
    11401 tatcagctat gaaaaatata tagttactgg tatgaaaagt attttaatga aagcaaagga
    11461 ttctaagaaa aaaatattgg catatattaa taataattta caaaatctta tagttagaaa
    11521 tgtaatcaga ccaacgcaaa gatatgctga tatgttggaa ttttcatacc atcctaattg
    11581 cttttctaat gcaatagaga gagaaaaagt acttcataat atgtgggcct atccatataa
    11641 gaataagaag gttgttcatt acgaattttc agacttaata gatggggata tacctatttt
    11701 ttataacaat atctcaaaaa catcattaat agctagtgac gggtacttag tagaagattt
    11761 ttatcaagaa agtgctttga atagatgcct aaataaaata aatgatcttt gtgatgaaga
    11821 tatttctatt caaaccgttt ggctagaaat tgctttgaat atttataatc catataaata
    11881 tattaatgat ttgaaaaatc aaaattcaaa taaatatatt tatactggct cagagctaaa
    11941 cagtaaaatt attcaagcat gtcagaagat agagaaaaaa attttcaaga gagctatttt
    12001 taataaaaaa accaatactg taaattggat tgacataaaa ttggatcaag attggaatgt
    12061 gggcatccta aataataata tgtacgatgg attgcctggt atattcgtat tttatgtggc
    12121 tcttaaatac attacaaaga atcataaata tgactatgta attgaatgta taaaaaattc
    12181 aatttataca ataccatctg aagatatatt gtcagctttt tttggaaaag gaagtttaat
    12241 atatccttta cttgtagatt accgcttaaa taatgatata aactctttaa atgtagccgt
    12301 agaaattgca gacatgttga ttgaaaagaa atcgataaat aatggcgagt taaaaaatga
    12361 ttggatccac gggcataata gtataataaa agttttatta ttgttatccg agataacaga
    12421 ggatgagaag tatagaaaat tttcattaga aatttttgaa aaattatccg aagaacccta
    12481 ttttaatttt agaggattcg gacacggtat atatagctat gtccatcttc tatcaaaatt
    12541 caataggata gataaggcaa attctttact tcataaaatt aaagaatcat actttgaaga
    12601 agaacctaaa aacaatagtt ggtgtaaggg aactgtaggt gaacttttag cgacaattga
    12661 attatatgat gataacattt caaatataga tattaataaa accatagcat ataaaaataa
    12721 agattgtctg tgtcatggaa atgcaggtac tttggaaggg ctaattcaat tagctaaaaa
    12781 agatcctgaa acttatcagt ataaaaaaaa taaacttatt agctatatgc taaatgattt
    12841 tgaaaaaaat aatacactaa aggttgctgg aagtgagtat ttagaatcac taggattctt
    12901 tgtaggaatc agtggtgtgg gttatgaatt attgagaaac ctagattctg aaattccgaa
    12961 tgcattactt tttgagttat aagaggtgta attatgaaaa gattgaagta tgttgcgcaa
    13021 ggagagcata gtgaatgtgc tttagcatgt atcactatgc tacttaatta ttatggtaat
    13081 caaagtacac tagtagaact aagggaaaaa tatggggtgc ccaaaggagg actaactatc
    13141 aaaaatattc gtactgtctt tgacgaatat ggatttgatg tatcgacatt taaatcaagt
    13201 ttttcaaatt atttagatct tccgactcct gtaataagct attggaataa tcaacatttt
    13261 gtggtcatag agaaaataaa aaagaagaaa atattaatct tagatcctgc aagtaataaa
    13321 cgctggattg atatttcaga atttaaaaaa aatttttcca atatattaat atacgcacat
    13381 aagaaaaaga ctaaaaaaga aggcgaaagg aaacagtttt ttttaaagtc atttattttt
    13441 acaaaattca aaagatattt ctttagtcta ataatattat catttgtttc acaactttta
    13501 ttactcttaa ttcctattgc aacaaagtat tcgatagata atattagatc ttttcaagaa
    13561 attcctacct atattctgtt attaatatta actagttttt tttctgtttt atatgtagtt
    13621 caatacttaa aaagctctgt agtagcagaa tttcagtatg aatttgattt taaattaatg
    13681 ttttcttata ttgataaact ttttagtatg ccactaatgt attttagtaa tagatcaaca
    13741 ggagaattag tgtttagagc gaacttaaat atttatatta ggcaaatatt gtctcaaaag
    13801 gtcataacaa ctttaataga tagtcttttt ttagggatat atttgttttt aatggttaac
    13861 tattctattt tactgacaat aatagctctt gttctaatct ctttaatagc ttttttaagt
    13921 attataaatt cgcatacaat aaaaagattt gtagataaag aaataatgga acaaggaaac
    13981 gtccagagaa ttattacaga agcaattgaa ggaattgaaa caattaaatc tgctaacgca
    14041 gaaaagagct ttttgttaaa ttggaaaaac atgtttacgt ctcaactatt aattaccaaa
    14101 aataaaaata gatatatagc tatttttgga atattaccag aaatcataca aagtgtaatg
    14161 ccagctctat ttttaataat aggtataaaa ttaataatca acaattcttt gtcattagga
    14221 tcactaattg gttttgtttc tatagtaaca atggttatga agccaattct aagtttggtt
    14281 tcctcttata atgactttct actattaaat gtatattttc aaaaattatc tgaagtttta
    14341 acttatgaag aaaaaaataa ttttaataat aaaataggaa atgttggaaa agaagagttt
    14401 atttataggg ttaataatgt ttactatact atatctgttt ttgaaaaaaa tattttaaat
    14461 ggtatttctt ttgacataag aaaaggggat aaagtagcta ttgttgggag aagtgggtca
    14521 ggaaaatcta ctttactaaa actattggcg ggattgttac aaccttctaa tggagaaata
    14581 ttgtatgaag gctatccttt atcaaacaac tccaataata gaagaaacat tttttatgtt
    14641 aatcaaaatg cgcatatctt taatgaaact atcgaaaaaa atatttcttt agagtttaaa
    14701 ccgaattctt ctataaatga gaaaaaaaga ctaaaagaaa gtatgaataa atcaaaaatg
    14761 gatgaggtac ttttaggaat tcctcagtat gagaaaacta tagtatcaga aaatggtagt
    14821 aatttctctg gtggtcaaag gcaaaagatt gctttagcta gagcgttcta ttctaatgtg
    14881 aatacattac ttttagatga gcctacatct gcaatggata atatttcaga atttgaagtt
    14941 ttttctaatt tattagatga gaaaagaaca gttattaccg ttgctcacag aattagtacc
    15001 gtgaaaaact ttgataaaat tatattaatg gataatggtg aaatagtatg tattggagag
    15061 catgaggatc ttattgaaaa tagtgagtta tatcgttcac tgtattacaa aaaacaacaa
    15121 tttggaggta caaaatgaaa aaaagaggat ttacttatat tttaatctca tatatttttt
    15181 taacattagg aacaacaggt tatgcatcag atctttcaaa taatatttca ttttttattg
    15241 ataattcgca aacaactgct atagaagaaa ttgagtctga attatcttct gaaaaagtag
    15301 attatataca ggaaatagga ttagttagtt ttaaaaacct ggatgatagt gataggaagt
    15361 ttataggtaa atattttaat gtttcggaag ggaaaaaatt accagatttt aaacctgaag
    15421 aagttaatag ttctatttta aacattaata ttttaaacaa agattttaag tcttttaatt
    15481 ggccatataa aaaaatttta tctcatattg atccagtgaa agaacaacta gggaaagata
    15541 taaccatagc tctaattgac tcggggatag ataggcttca tcctaatctt caagacaata
    15601 acctaagatt aaaaaactat gttaatgata ttgagttaga tgaatatggt catggtacac
    15661 aagttgctgg agtaatagac acgattgctc caagagtaaa tttaaattct tacaaggtga
    15721 tggatgggac agatggaaac tctataaata tgcttaaagc tatagttgat gctacaaatg
    15781 atcaagtaga tataataaat gtgagtcttg gctcatataa aaatatggaa atagatgacg
    15841 aaagatttac tgtagaagca ttcagaaaag ttgttaacta tgcaagaaaa aataacattc
    15901 taattgttgc atcagcagga aatgagtcgc gtgatataag cactggtaat gaaaaacata
    15961 taccaggagg actagagtct gtaattaccg tcggagctac aaaaaagagt ggtgatattg
    16021 ctgactattc taattatggg tctaatgttt ctatatatgg tcctgcggga ggatatggtg
    16081 acaattacaa aataacagga caaattgatg ctcgtgaaat gatgatgact tattacccta
    16141 catcgctagt ttctccacta ggtaaagctg ctgactttcc agatggctat acactttctt
    16201 ttggaacaag tttagcaact ccagaagtaa gcgcagcttt agcagctatt atgtcaaaga
    16261 atgtagataa ttttaaagat tcaaatgaag tattaaatac tttatttgaa aatgctgatt
    16321 cttttataga taaaaatagc atgcttaaat acaaagaggt gagaataaaa tagatgaaat
    16381 ttatatctcc gatgatcttt acgttacttc tcgtaatctt tactcttgtt tttgaattaa
    16441 atttagtgtc tactgcatac ttttccttgt tattgtctat ctttgtacat gagttaggtc
    16501 atttagtttt tggattattt aataaagtta gaccagagtc attaatattt gggtttataa
    16561 aactttcgtg ggaaaaacag tttaaggtta gattaaatac acagtgggga ttttttggtg
    16621 gattatttag atataaacca actacgttta ataataagaa aattctgagg ttgttaaccg
    16681 gaggaccaat atttagtctt ttttttacat taactttttt tgtaaaaatt gaattttttc
    16741 aatatttttc tttatttaat ttttcaatat tcttgattac tgcagttcct tttaatttta
    16801 acgggtttat gaatgatgga tacaatatat ataaattagt tactaaggat tatattttcg
    16861 aaatgtatta tattgtatca aatagcttac ttaataaata taatcagtca actttcttaa
    16921 atagcaatga ggtatgcaaa ataataaaaa aaaataaaga attaccatta tatgtgctaa
    16981 atacattctt actgtatgtt atatatgagt atttaataga caaaaataat aggaaattaa
    17041 aactaatata cccaatactt agtaaagaag acaagatact gaataataaa agttatttac
    17101 agaattttta tttagccaat ttgtatatga tagaatatat cttatctgta gataataaac
    17161 aaacttttaa aaaaattaat ttaaaaattc tagactcaat tagtagatct agaattaaat
    17221 atctaaactt taaatgctca aaaagtgctg atgatgaaat aagccaatca atgacagaat
    17281 ttagcaatat cataaaaaat tattcagatc aaacgtcaac tatgattata gcagaaaaac
    17341 aatgggttca aaattgagat aagaaaccag ctagactgtc gacgtaaaat gataggctaa
    17401 aaaaagtgat gtgtgcttgc tacgattttt atacagtatt taatgatgta ataaataaat
    17461 tttctattaa aatatattaa ctaaaaaacc aacagggtat gccttgttgg tctttttaat
    17521 attctgattg ctactaggta agtggtaggc cattcaagtt gggcatattt catttgcgta
    17581 aatttttagt atgcctgtac tgtattatta agaacttttt aatcatactt ataggaacca
    17641 tactagtaga tattttggtt ttatgagtat ctgttagaga tgaaaagtca aaatgtgtta
    17701 tatccttaga gactgttctc ccccccaaaa aaaagacagt ctttattata catttgaatg
    17761 tatgctaaaa ttgatataaa gaacagatct atctagttaa aagtacctat tatttggaat
    17821 catgggaact taattacata aatagtaaag gggattgtca tgggaagacc aataaatttg
    17881 tattcattta tggatataat gaatacaacg aaagatgatc aattaattaa ttcaatgttg
    17941 aggttatgtg atgatagtat agtacataat ccagaacaat tttttaggaa aaaggaactt
    18001 caaaatcttt atcagttttc agaaaaatta ttgccggtgt taacgaatat acctaaagct
    18061 gacaactatt ttataggaca ctctgtttca attggtataa caaggcagtt tgatgtatta
    18121 agatttagtg caaaaaaagt tgtaaatatc gagttaaaag attgtatgcc aagtaaagga
    18181 ctagaagcca taaaaagtca attaataaag aatcaattct ttttgaaagt cctaggtaag
    18241 gaaataatct catgtactta tgtagctgat atagagaaaa tctacacgtt aacagctgat
    18301 gacgaattaa atgtacttga gtttgaaaga ttaggtgaat taataccttt agatagttta
    18361 gacgtaaatg aattagaatc tcaacagctg actaatttta ttatctcacc atactcagag
    18421 acagatagat ttgtaagtca cacctatttt cttactgatc agcagctaac taaaaaatat
    18481 gaaataatac aatctaattc aaaaaaaatt ggagttattg gcggagctgg aacaggaaaa
    18541 tctattttat tatttgattt agcgcagaca tgggtaaagg aagggaaaaa agttttagta
    18601 atatttgttg gacaattaaa caattatatg tcgataagtg aaaaattcgg attcgaaatt
    18661 gttccaattc ggcttatgaa tagaaaagaa atattagaag gtgcatacga tattgtgata
    18721 gttgatgagg ctcagaggct aatgacagat cagtatgaat ttttgataaa gttagaaact
    18781 aaaattattt tatctgtaga tcgttcacaa acactacacc cttcagaagc cgatagaaat
    18841 attgaaggtg aaatagaggt taatccaaat tttaaagtgg tgaaattagg tgagaaaata
    18901 cgtacagaca aggaattggc tgactttata agtaagttaa tgaacttatc tgccagaaat
    18961 atttcacccc atgattacaa taatataagt atcaattatt ttgaatcgag ggaggttgct
    19021 aaagatttta ttgataacaa agttgctcat gactgctgga tatcgataga atttacagaa
    19081 tatgtaacac agtttactgg aaccaaaaaa aaatctatga tttctaatcg ttctctgtct
    19141 gcccatgagg tggttggaaa agaatacgat aaggttatta ttgtcataga taatttagtt
    19201 agacgtggaa gagatggtaa attaatttat ttgagtggtg aggagtggta tccttatctt
    19261 gaaatgcgat tattgttaga agcattaaca cgtgttagaa gtaagttgat gttagtagtg
    19321 gttaacaatg ctgacatgta tgttgatata caaagaaatc tactgtcctg gaaaaatgat
    19381 caattagctg gaattaaaac atacgacaaa gagctaaatt atgatggctg ggataatgcg
    19441 attggaaatt tagaaattca tgttaatggt attatgtata aagcttctaa agttgaatat
    19501 atagaaaaaa caagaaaggt aaaagtctca tatttcgcag tggaataaat ttaaagatta
    19561 ttaattaaat tagttatctt actatagtta gttgtgtctt attcaactaa aaacaaaggg
    19621 gtcataaact ttaagttttt gacctctttt gtttttcgtg ctatacttgg aattatctag
    19681 tgtcaaaaac ttatgttcag aaaaggtgag gaaattttgc ccatttatgg ttattcacga
    19741 gtgagtacta gtaatcaaga ttacaaaacc cagattcaaa aactagaaaa agccggagca
    19801 gaaaaaatat tcagtgaaaa atacacaggg actaaaaaag aaggaagaaa agaattagaa
    19861 gaactactat ctattgtaaa acatggcgat aaagttttag tgacgaaaat tgatcggcta
    19921 gctagaagta tcgttgattt aaattcgatt atctcttctt taaaccattc aggagtgact
    19981 atcaccttct tagataatgc tctaaccttt gagccaaata aaagtgattc tatgcaaaca
    20041 ttaatgatga acatgttagg gagttttgcg caatttgaaa gagatttaat cgtgacaaga
    20101 acgcaagaag gaaaacagtg gcatagagct aataataaaa attatcgaga aggacgtccg
    20161 aaaagagttc tgaatgataa atataaacat gcactagagt taatggaaac aaacagcatg
    20221 cgagaagtgg aaaggaaaac aggtatttct ttatctactc tcaaaagaat caagaaacaa
    20281 gcaaaggaag aacagttact taatgagaaa taaattagga atggtgaaca tagaaagtag
    20341 ggaaaagatt attaagttgt tggaaaatcc tttagtcttt ttatgaatta aattaattaa
    20401 atattttcgc aaaataatac aaaaattttt attattttag aagggattgt gtataatgtc
    20461 tgaatcagtg ggtattattt taggagccgt tatagcatta tttgggacta tagttacgaa
    20521 ctatttcacg atgaaaaaaa ctagattaca ggaagaaaaa aatagtgata gatttttaaa
    20581 aaaattgaaa gctgaagaag aaatagaact taaaactttt gagcataaca ttgttatgaa
    20641 caatagagaa cacattccaa atgcggctag agatatagta gttgaaatta atcaattatt
    20701 tgattctaca gaagaattag tttttaacta tcctggaacg ggttatacag gagaacgacc
    20761 atcaatttta tttagtagta caattgatca tttaattaca gggtttccaa attcaatgga
    20821 agatataaaa gaactaagta atacatggta tcattctaat aagaaattca agaacgttat
    20881 atttgaaaat tcaatgtttt ttcccactga attaatgaat gagatttggg aatatgaaaa
    20941 atattgtagt gatattaagg attattttta tgggcgttat tctagtataa aaagtgaaga
    21001 ggaatttagt gcaaaaaaaa atgaatatca agaacaagtt gataaatatg tttttattca
    21061 aaaagatggg atagcaagtt acactcatag tgtacttagt atttataata cagtaaagaa
    21121 atctagatcg gatttagtaa ataagataaa cacgtatcag aaacaaaaaa caggttttta
    21181 atatcttaat aaaaacggag caaatagtgg aaaggaggcc gagatatggc aacgattaga
    21241 attgatgatg aattaaaaca taatgcagat aaaatgtttg atgaagtggg aataaatacg
    21301 ttgattgcag gtgaaatgtt tttgaataga tttgttaaga ctggaaaatt tccatttgat
    21361 attgagataa ttttttatca gccgaatact taaacattgt ggatgtactc aatttaaatg
    21421 taatagctgc aaaaaagaat gcaaattata tcaaggaaac tatgttgtaa ttgatgaaaa
    21481 acaaatgaac tagatcaaaa taatggaaaa ggagattttt aaatatgtac ttttaataat
    21541 tgaaaaatta tgaaggattt attacgcatg aacgttggta gagttcaacg tgtcgaatat
    21601 ggtataataa gcaagtagaa agtttatggc ggttggctaa acccaaaaga aatggggtga
    21661 tgcctatgtt gatttttggc tttactcctg gaaaggaata aatgtgtctg tatttgaagc
    21721 attgatgttt tcgatgactt tcgcaacatt gattctaaaa atcagcgata aaaacaacaa
    21781 aaaatagacc gtcataatct ttggccagac tgacaggtct atttttgact tttaattctt
    21841 gccaccgctt taaacggtct acatggggac gtatcacgag tacggcctct tttcaatact
    21901 tattataaca gtaactatta aaataatcta gtaaagtagc tatcaaatta tataactaaa
    21961 gtaaaaaggt ggagagtttt atgaattttg gctatttgaa ttttggaata aaagacgcaa
    22021 ttctagcaat tgttatattt attatcttac ttttgacaat attgtttcat tggtcagctt
    22081 tagaatttgt tttttcttta ggtgcagtag tgattgcttt ttttgctgga aatatgaaac
    22141 aggataaaag agttgtagaa aaacaaaata aaaagaaatg atacacaagg aatgaataag
    22201 gcttacaaac ctgaaaataa aaaattgagg tagtttccca atagagtttt accaattagc
    22261 atagtgttat tgtgcttagt aagtagcaac catttgtttt tttgacactt ttctgaaact
    22321 atacatgata aattttctag agaacttaat acggaaatag gtgataaatt atattctcaa
    22381 gaaattgctt taaataaaaa attagctgat caagtttctt tatttggttc acaatatttc
    22441 tccgcatttc taaagttatt agaattgaac cctgatagtg atttgaaaag aattattata
    22501 gcttttttag agttactttt aggctcttta ggacaaaaac tagtatctca attaaatgaa
    22561 gaactatttg aaaaagcacc gactactgtt aatatattcg atgatattag tggtattttt
    22621 aatataaact attctagcgt tgggaaagtt ggaatggaaa tcgtaattaa tcaaacaaga
    22681 gaaccagtag acaagaatac tgacatcaat aaaatattta ttgaattagg aaagacaata
    22741 ctggaacaaa tttatagtca aacgttggat tatcaatcat tgatagatag tcattttcgt
    22801 tatttataca atccaaaatc tcaatgggca aaatttacta aaattgctgt atttttatac
    22861 actgttcagc gatatatcaa gaatcaaaca aatatagatg aagataaaat taaaaatggt
    22921 ccaggatttt accacgattt aattgatata caaaatgatt ttgatttaca tgcaattgga
    22981 ac
//
