LOCUS       NZ_JAGKQT010000023     24690 bp    DNA     linear   CON 29-AUG-2024
DEFINITION  Priestia filamentosa strain JURBA-X PF_18_scaffold2, whole genome
            shotgun sequence.
ACCESSION   NZ_JAGKQT010000023
VERSION     NZ_JAGKQT010000023.1
KEYWORDS    WGS; RefSeq.
SOURCE      Priestia filamentosa
  ORGANISM  Priestia filamentosa
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Priestia.
REFERENCE   1  (bases 1 to 600861)
  AUTHORS   Murthy,S., Govardhana,M., Sharma,G. and Belur Satyan,K.
  TITLE     Whole Genome Sequencing of Drought-tolerant Plant-Growth Promoting
            and Florescent Bacillus filamentosus JURBA-X
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 600861)
  AUTHORS   Murthy,S., Govardhana,M., Sharma,G. and Belur Satyan,K.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-MAR-2021) Institute of Bioinformatics and Applied
            Biotechnology (IBAB), Jain University, Electronic City Phase I,
            Bengaluru, Karnataka 560100, India
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: nextflow-tychus v. 0.23.0
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 600.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_018971125.1-RS_2024_08_29
            Annotation Date                   :: 08/29/2024 03:01:25
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,686
            CDSs (total)                      :: 4,602
            Genes (coding)                    :: 4,566
            CDSs (with protein)               :: 4,566
            Genes (RNA)                       :: 84
            rRNAs                             :: 7, 10, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 8 (5S, 16S)
            tRNAs                             :: 62
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 36
            CDSs (without protein)            :: 36
            Pseudo Genes (ambiguous residues) :: 0 of 36
            Pseudo Genes (frameshifted)       :: 14 of 36
            Pseudo Genes (incomplete)         :: 23 of 36
            Pseudo Genes (internal stop)      :: 10 of 36
            Pseudo Genes (multiple problems)  :: 11 of 36
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 22:40:31
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 458850
            Orig. end                         :: 483540
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JAGKQT010000023.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..24690
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="betalactone"
                     /region_number="1"
                     /rules="(HMGL-like and AMP-binding)"
                     /tool="antismash"
     cand_cluster    1..24690
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(HMGL-like and AMP-binding)"
                     /kind="single"
                     /product="betalactone"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..24690
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[10000:14690](-)"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..14690)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="1"
     misc_feature    complement(867..880)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.93"
                     /tool="antismash"
     misc_feature    complement(1164..1179)
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 20.1"
                     /tool="antismash"
     gene            1178..2029
                     /locus_tag="J2M30_RS22590"
     CDS             1178..2029
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019394157.1"
                     /locus_tag="J2M30_RS22590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="WP_216701208.1"
                     /transl_table=11
                     /translation="MENIYIHIAEQMPSMSKANMKIAKYILENPNTVPFLTADKLAKIT
                     KVSHATVVRFATFLGCSGYPELQQYMQNSAQQQLTTTDRLKISKEVYNDEDQGIYDIFL
                     DDISNIKSTFEKLDIDMFKQAVDRLIQAKRVYIVANRSATALGVFLQYYFQFLLDKVEL
                     IHSIETVSERLYDLNKDDVVIGISFARYTKSTIQVLEYAKEREASTIAITDNLLSPLIP
                     YADMPLTASSQMPTFIDSFVAPLSLINALIISVGRGREEKFQNKLESLEEIWEKFDIFY
                     KK"
     misc_feature    complement(1202..1215)
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: medium, score:
                     16.06"
                     /tool="antismash"
     gene            complement(3218..3487)
                     /locus_tag="J2M30_RS22595"
     CDS             complement(3218..3487)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019394154.1"
                     /locus_tag="J2M30_RS22595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_019394154.1"
                     /transl_table=11
                     /translation="MLKVKVKVKDKRFSIPVPYTVLNLVSLIVTSKRINRLINKAIEKD
                     GSKFIFPEIERKDLKLLLQGFSKYSGVILVETRLKDGTEVEVKL"
     gene            complement(3491..3880)
                     /locus_tag="J2M30_RS22600"
     CDS             complement(3491..3880)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013058378.1"
                     /locus_tag="J2M30_RS22600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_019394153.1"
                     /transl_table=11
                     /translation="MKDEISRVLTLVEEGKIDKEKASELINILQGKDQPELVTINKEVP
                     YGNKMLKIRVSSEEGDNVNVNLPINLVKAVLKVGTNIAEKIPEAEKYVKDINIDLLIEA
                     IENELDGQIVDITSSKGDKVFVVIE"
     gene            complement(3880..4251)
                     /locus_tag="J2M30_RS22605"
     CDS             complement(3880..4251)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019394152.1"
                     /locus_tag="J2M30_RS22605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF2089 domain-containing protein"
                     /protein_id="WP_019394152.1"
                     /transl_table=11
                     /translation="MAYPLLTNCPVCTKALKITKLQCNHCQTTVENEFEVSRLAALGQE
                     QLHFIEIFLKCRGNIKEVEKELGISYPTVRGKLDEIISTLGYSSQKKPEVDKKKIVSLL
                     EKGEITAEKAIQLLKEGEV"
     misc_feature    4321..4334
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 23.23"
                     /tool="antismash"
     misc_feature    4322..4335
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: strong, score: 24.21"
                     /tool="antismash"
     misc_feature    complement(4512..4526)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 22.67"
                     /tool="antismash"
     gene            complement(4916..5548)
                     /locus_tag="J2M30_RS22610"
     CDS             complement(4916..5548)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019394151.1"
                     /locus_tag="J2M30_RS22610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_019394151.1"
                     /transl_table=11
                     /translation="MNKKTVVLCVSIVGALTMSSLSGCASEEKSPTINTDTSQKQTNLQ
                     KYTKYPEKNGNQDEEFDLVGTLDKETQDELTLIIDNEKVKIPKRNTFEKEDEINGDIKG
                     ELVKIEVNTKGQNAESLELTPQAKANDEGIYEKESDGDYNVIGKLINETSNEVTIEVHN
                     GKKTYTKANDFEKDVDNKSQDIQGKIVRLEVKKNNKVESLEVESEDQ"
     misc_feature    complement(5694..5708)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 22.4"
                     /tool="antismash"
     gene            complement(5859..6872)
                     /locus_tag="J2M30_RS22615"
     CDS             complement(5859..6872)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014460649.1"
                     /locus_tag="J2M30_RS22615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="YeiH family protein"
                     /protein_id="WP_239695510.1"
                     /transl_table=11
                     /translation="MLLRTEVKKLSSFALWFVGIGFTFIIALMGYGLAKVPGFNHVGQL
                     ACAIVIAVIYRQMWGYPESIRSGVEFSSKRLLRFAIILFGLKLNIDVVIHQGLGLLVRD
                     VGTIVFSIFLTVLIAKWLKADASLSLLLGIGTGVCGAAAIAAVSPILKAKEKDTAIGAG
                     IIALVGTIFAIGYTILRPYIGLTDVQYGIWAGVGLHEIAHVALAAAPGGRDALAIGLLA
                     KLGRVFLLVPLSFILMYWMKRTGKVQEDTKIEFPWFLIGFIMMSVFGSYVLGKYIIISK
                     NIMNDISGLTTFILTMAMVGLGLNVSLKDLRTKAFKPLIAMFITSILLSFFTFLIM"
     gene            complement(7619..9157)
                     /locus_tag="J2M30_RS22620"
     CDS             complement(7619..9157)
                     /EC_number="6.-.-.-"
                     /GO_function="GO:0016874 - ligase activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1059: acetyl-CoA carboxylase, carboxyl transferase,"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019394148.1"
                     /locus_tag="J2M30_RS22620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="acyl-CoA carboxylase subunit beta"
                     /protein_id="WP_046217401.1"
                     /transl_table=11
                     /translation="MDMKPLQQILEERVERIKKGGALKYHEKNTEQGKLFVRDRLKQLF
                     DPGFELEDALFANCMAGELPADGVVTGMGKINGQVVCVMANDSTIKAGSWGSRTVEKII
                     RIQETAEKLRIPLIYLVDSAGARITDQVEMFPGRRGAGRIFYNQVKLSGKVPQICLLFG
                     PSAAGGAYIPAFCDIVIMVDKNASMYLGSPRMAEMVIGEKVTLEEMGGARMHCSVSGCG
                     DVLAKNEEEAISIARNYLSYFPANFSEKPPVHEAVAPKQMKKSLEELIPANQNSPFNMH
                     DLINGIIDEGSFFEIKKLFATELITGLARMDGKPIGIIANQPRVKGGVLFHDSADKAAK
                     FINLCDAYHIPLLFLVDVPGFMIGTKVERAGIIRHGAKMISAMAEATVPKISVIVRKAY
                     GAGLYAMAGPAFEPDACLALPSASIAVMGPEAAVNAVYANKIAVLPEEEKAAFIAEKRA
                     EYKEDIDIYRLASEMVIDGVIPANSLRDELTKRFEAYSSKYLIFSERKHPVYPV"
     gene            complement(9188..9970)
                     /locus_tag="J2M30_RS22625"
     CDS             complement(9188..9970)
                     /EC_number="4.2.1.17"
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: ECH (8-252). E-value: 3.2e-73. Score:
                     238.0. Matches aSDomain:
                     nrpspksdomains_J2M30_RS22625_ECH.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1023: enoyl-CoA hydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019422141.1"
                     /locus_tag="J2M30_RS22625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="enoyl-CoA hydratase"
                     /protein_id="WP_046217402.1"
                     /transl_table=11
                     /translation="MNKMILVNRLENGIVMITLNRPEAANALSLQMLGELQEAVLLCKY
                     DRTIRCVVITGGGEKAFCAGADLKERADMDQIQVRKTLALIRENINDLESLPQPIIAAV
                     NGVALGGGTELALACDIRIASETAKLGLTETSLGIIPGAGGTQRLPRLVGKGRAKELIF
                     TARRIDAAEALEIGLVEHTAPSNHLIKKALEIAGQIVRNGPIAVAQAKFAIDKGYDVDM
                     NTGLAIEQSAYEVTIPSKDRLEGLQAFKEKRTPIYIGE"
     aSDomain        complement(9215..9946)
                     /aSDomain="ECH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_J2M30_RS22625_ECH.1"
                     /evalue="3.20E-73"
                     /label="J2M30_RS22625_ECH.1"
                     /locus_tag="J2M30_RS22625"
                     /protein_end="252"
                     /protein_start="8"
                     /score="238.0"
                     /tool="antismash"
                     /translation="RLENGIVMITLNRPEAANALSLQMLGELQEAVLLCKYDRTIRCVV
                     ITGGGEKAFCAGADLKERADMDQIQVRKTLALIRENINDLESLPQPIIAAVNGVALGGG
                     TELALACDIRIASETAKLGLTETSLGIIPGAGGTQRLPRLVGKGRAKELIFTARRIDAA
                     EALEIGLVEHTAPSNHLIKKALEIAGQIVRNGPIAVAQAKFAIDKGYDVDMNTGLAIEQ
                     SAYEVTIPSKDRLEGLQAFKEK"
     gene            complement(10001..10900)
                     /locus_tag="J2M30_RS22630"
     CDS             complement(10001..10900)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: HMGL-like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1271: 2-isopropylmalate synthase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019394146.1"
                     /locus_tag="J2M30_RS22630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hydroxymethylglutaryl-CoA lyase"
                     /protein_id="WP_040057466.1"
                     /sec_met_domain="HMGL-like (E-value: 2.2e-55, bitscore:
                     183.2, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKWPKNITIKEVGPRDGLQNEKDFISTEDKISLINQLSASGLKSI
                     EITSFVNPKWIPTLSDATAVATGITKVPGVTYTALVPNQKGLERAFEANVDEVAVFMST
                     SETHNLKNINKSISDTFPILRNLVQKTLAVGKPSRGYVSTVFGCPYEGPIDINEVIRVS
                     ETLFEMGINELSLGDTIGVANPKQVQELLEVFLKRFPADKLAMHFHDTRGTALANVLVS
                     LEMGITTFDSSIGGLGGCPYAPGASGNVATDDLLYMLHGMEIHTGVDQKKLLSASQFIQ
                     KKIGRPLPSKSLQASTSQ"
     gene            complement(10935..11147)
                     /locus_tag="J2M30_RS22635"
     CDS             complement(10935..11147)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013876843.1"
                     /locus_tag="J2M30_RS22635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein subunit"
                     /protein_id="WP_046217403.1"
                     /transl_table=11
                     /translation="MSEIVASMAGNVWKVLVKVGDQVEEGQDVVILESMKMEIPIAAES
                     GGTVKEVKVNEGEFVNEGDIIVKVE"
     gene            complement(11161..12522)
                     /locus_tag="J2M30_RS22640"
     CDS             complement(11161..12522)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Dala_Dala_lig_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1090: acetyl-CoA carboxylase biotin carboxylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019394144.1"
                     /locus_tag="J2M30_RS22640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="WP_019394144.1"
                     /sec_met_domain="Dala_Dala_lig_C (E-value: 5.6e-14,
                     bitscore: 47.3, seeds: 12, tool: rule-based-clusters)"
                     /sec_met_domain="ATP-grasp (E-value: 1.7e-09, bitscore:
                     32.8, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFKKVLIANRGEIAVRVIRTCKALGIITVAVHSEADADAPHVKMA
                     NEAHLIGGSRVAESYLNIDKILEVARLTKAQAIHPGYGLLSENAEFARRCGKEGLIFIG
                     PSPEVISKMGSKIQSRKAMEEAGVPVVPGITYPLADAEEAVEAADFIGYPVMLKASAGG
                     GGIGMQVVHSGDEIRKAFAGNQKRATDFFGDGTMYIEKFVENPRHIEIQILADGFGNTV
                     YLWERECSIQRRHQKVVEEAPSSFLSETTRRKMGEAAVKAAKSIGYKNAGTIEFLVDEE
                     QNFYFLEMNTRLQVEHPVTEEITGLDLVEKQLKIAGDEALDFSQEEVKREGHAIEVRIY
                     AEDPKTFFPSPGKITKLELPKGSGIRHELAVHDQSVVTPFYDPMIAKLIVKGNDRDDAI
                     NRLHGALVDYHIEGIKTNIPMLKEVIAHPAFRSGDTTTDFVGKYLKTKKTNNAE"
     gene            complement(12723..14690)
                     /locus_tag="J2M30_RS22645"
     CDS             complement(12723..14690)
                     /EC_number="6.2.1.1"
                     /NRPS_PKS="Domain: AMP-binding (92-526). E-value: 5.2e-84.
                     Score: 274.1. Matches aSDomain:
                     nrpspksdomains_J2M30_RS22645_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019394143.1"
                     /locus_tag="J2M30_RS22645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="acetate--CoA ligase"
                     /protein_id="WP_046217405.1"
                     /sec_met_domain="AMP-binding (E-value: 3.5e-93, bitscore:
                     307.6, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDINGISQVVANSKLIFPNKEKVRSTSIGSIEAFQELLRQSQEDP
                     AAFWDSAARDLVWYEPWKETISGQLPDFRFFVDGISNPSVNLLDRHIANGAGNRTALIW
                     EGENGDTKFYTYNMLLAKVNRFANVLRSFGVKKGDCVAIFLPNLAEACIAVLACFRIGA
                     IYNTIFSGYSEKSLKDRLISFEPKIVVTADATERRGKAIRLKEKVDQVVPTIPSVEAVI
                     VVSRLGLEVPMKEGRDYWWHELTKTASIVCEPERIEANEGGIVFYTSGTTGKPKGVVHS
                     GMAFVIQNYTYAKYHMDHHNDDVFWCTADIGWLTMHIWGITGALANGVTTVVYEGAVDY
                     PEKNRFYQIIEKYRVNKLFTAPTALRMLKSMGEKPLEQFDLSCLDVISLVGEPFDTETW
                     HWTYEVLGKKKVYINNTWGQTETAGSPIAGAAWLTPMKPGSAGTQFLGAVFNVVNEEGN
                     PVKSGQLGNLVIRKPFPMLCRTLWKEPERYYASYFSQVEGSYYASDLALIDKDGYIWVV
                     GRSDDALNVAGHRLSTLEMESAVLECEGIFECAVIGIPDEIKGEVPLVFARLADGFEDN
                     EEMIERINRSIIQQIGKIASPKAIIMTNMLPKTVSGKIMRRLLKEIVATGKVAGDITGL
                     EDPSTVVEIQKIVASKLSAI"
     aSDomain        complement(13113..14414)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_J2M30_RS22645_AMP-binding.1"
                     /evalue="5.20E-84"
                     /label="J2M30_RS22645_AMP-binding.1"
                     /locus_tag="J2M30_RS22645"
                     /protein_end="526"
                     /protein_start="92"
                     /score="274.1"
                     /specificity="substrate consensus: Ala"
                     /tool="antismash"
                     /translation="ANGAGNRTALIWEGENGDTKFYTYNMLLAKVNRFANVLRSFGVKK
                     GDCVAIFLPNLAEACIAVLACFRIGAIYNTIFSGYSEKSLKDRLISFEPKIVVTADATE
                     RRGKAIRLKEKVDQVVPTIPSVEAVIVVSRLGLEVPMKEGRDYWWHELTKTASIVCEPE
                     RIEANEGGIVFYTSGTTGKPKGVVHSGMAFVIQNYTYAKYHMDHHNDDVFWCTADIGWL
                     TMHIWGITGALANGVTTVVYEGAVDYPEKNRFYQIIEKYRVNKLFTAPTALRMLKSMGE
                     KPLEQFDLSCLDVISLVGEPFDTETWHWTYEVLGKKKVYINNTWGQTETAGSPIAGAAW
                     LTPMKPGSAGTQFLGAVFNVVNEEGNPVKSGQLGNLVIRKPFPMLCRTLWKEPERYYAS
                     YFSQVEGSYYASDLALIDKDGYIWVVGRSDDALNV"
     CDS_motif       complement(13848..13898)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_J2M30_RS22645_0001"
                     /evalue="8.10E-07"
                     /label="NRPS-A_a3"
                     /locus_tag="J2M30_RS22645"
                     /protein_end="281"
                     /protein_start="264"
                     /score="21.6"
                     /tool="antismash"
                     /translation="VFYTSGTTGKPKGVVHS"
     gene            complement(14737..15876)
                     /locus_tag="J2M30_RS22650"
     CDS             complement(14737..15876)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006: acyl-CoA dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019422145.1"
                     /locus_tag="J2M30_RS22650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="acyl-CoA dehydrogenase"
                     /protein_id="WP_048896805.1"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 7.9e-37, bitscore:
                     121.7, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 1.6e-27, bitscore:
                     90.9, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 6.7e-55, bitscore:
                     180.7, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNFDLTKEQEMIRKLIRDFSEAEVAPGADERDRTGAFPYEMFSKL
                     AELGIMGLPFPEQYGGGDADTISFAIVVEELSRVCASAGITYSAHISLGGEPLNLFGTH
                     EQKEKYLTPICTGESFGAFGLTEPNAGSDAGGTQTTAVLDGEEWVINGSKCFITNASYA
                     KHLAVTAVTDRSKGINGISAFIVPTNAPGFTVINNYEKMGLQSSNTTELILENVRVPKD
                     NLLGTEGEGFKQFLATLDGGRIGIGAMAVGLAQGAYEKSLQYAKERKQFGKSLSNFQAI
                     QFKLADMAMNIEIARNMVYKAAWLKEQGRIFKKEAAYAKLFASEICMRACDQAIQIHGG
                     YGYMKEYQVERFFRDAKLLEIGEGTSEVQRMVIAKQIGC"
     misc_feature    16143..16159
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 20.81"
                     /tool="antismash"
     gene            16692..17138
                     /locus_tag="J2M30_RS22655"
     CDS             16692..17138
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019394141.1"
                     /locus_tag="J2M30_RS22655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="RDD family protein"
                     /protein_id="WP_019394141.1"
                     /transl_table=11
                     /translation="MDHVIKPAGFWIRLLGNLLDGVIVSIPLTLIVFLLTGEVNENDPV
                     ISILGFIYTVAVPILWSGYTIGKRIVGVRIVKVNGKKLGIGAMLLRVLVAGIVYSLTLG
                     IALIVSLFMVVFRKDKRSLHDLMAGTYVTYAKPHEMEDKHTVAS"
     gene            complement(17440..18036)
                     /locus_tag="J2M30_RS22660"
     CDS             complement(17440..18036)
                     /EC_number="2.1.1.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003183757.1"
                     /locus_tag="J2M30_RS22660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_046217406.1"
                     /transl_table=11
                     /translation="MENNVFEQIAKRYDTEERIELAKIIVKEVRTELQNSKSSSLIDYG
                     SGTGLIGLELSDLVDSILLVDSSKQMLEVAEAKISQKEITNSTVLYSDFTQGTPDLKAD
                     IVLMSLVLLHIPDTKKILQELFNVLNDEGKLVVIDFDKNHKINHPKVHNGFSHEELKKT
                     LSEVGFKSIKITTFYHGNHIFMNQDASMFISSSIK"
     gene            <18144..>18233
                     /locus_tag="J2M30_RS23775"
                     /pseudo=""
     CDS             18144..>18233
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016766568.1"
                     /locus_tag="J2M30_RS23775"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="HAD family hydrolase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MTWLSFYTKEFSMNGVKDENILKETLSLNN"
     gene            complement(18687..19511)
                     /locus_tag="J2M30_RS22665"
     CDS             complement(18687..19511)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019394139.1"
                     /locus_tag="J2M30_RS22665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="STAS domain-containing protein"
                     /protein_id="WP_046217407.1"
                     /transl_table=11
                     /translation="MRNSNNDIQEMIHYVKAKREDFQQKLLSEAVNVAEVIHDILKQGN
                     IDLLKNAERLVVYILENNDQDIVVFAKQEGVAWAQYSLTLAFKLEWVQAIRRSLWKTIY
                     EYQSEFNLPSIREDFFELEERINNNIDQFLNTFFLSYSDFKDELIHRQRKNVEHLSVPI
                     IPISPTVAILPLIGTIDSYRMDTIEEKVLTDIARTRIHTLIMDLSGITDMEVVVIDHFH
                     KVLDGINMMGCKSVITGLRPELVREMIHLGINFNQKAITKGTLQQSLKDYLL"
     misc_feature    complement(19656..19673)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: medium, score: 19.83"
                     /tool="antismash"
     gene            complement(19784..20263)
                     /locus_tag="J2M30_RS22670"
     CDS             complement(19784..20263)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019394138.1"
                     /locus_tag="J2M30_RS22670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF2306 domain-containing protein"
                     /protein_id="WP_216701210.1"
                     /transl_table=11
                     /translation="MEIFNIILIIHIVCGIICLLFGLLAMSAPKRRGIHTKWGEVYHAS
                     YVGVFITAITLSILRWEEIAYLFYVAFFSYSFAIYGYLAGKRRWGNWLNHHIRGMLGSY
                     IGAVTALLVNIGDMLPLLNKLPKLWFWFLPTIVGVPIASIVVKKYRGGKKENINL"
     misc_feature    20346..20366
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 24.03"
                     /tool="antismash"
     misc_feature    20506..20518
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 21.78"
                     /tool="antismash"
     gene            complement(20533..20862)
                     /locus_tag="J2M30_RS22675"
     CDS             complement(20533..20862)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411497.1"
                     /locus_tag="J2M30_RS22675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="cupin domain-containing protein"
                     /protein_id="WP_026009694.1"
                     /transl_table=11
                     /translation="MEKINLLEITKDIKDQHVNFAVSDVNNHCLRIAVFSGEYEWHYHS
                     NSDELFMVLEGELLIDLKDKDTVVLKPNDTILIPAGTVHRTRAKQRTINLCFEDKNADT
                     IIIDK"
     gene            complement(20937..21608)
                     /locus_tag="J2M30_RS22680"
     CDS             complement(20937..21608)
                     /EC_number="3.5.-.-"
                     /GO_function="GO:0016812 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds, in cyclic amides
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013058484.1"
                     /locus_tag="J2M30_RS22680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="cyclase family protein"
                     /protein_id="WP_046217409.1"
                     /transl_table=11
                     /translation="MKRKKYIDLSHTIQDGIITYKGLPAPIICDYLSREESRKHYGEGT
                     EFQIGKIEMVSNTGTYIDVPFHRYANGKDLSEIPIDKMAGLEGVTIHIDKNKKEINEDV
                     FYDLDIEGKAVLIHTGWDQYWNTDQYFENHPYLTEKAAQYLVDKKAALVGIDSVNIDNT
                     SGKDRPVHTTLLGKEIFIVEHLCNLKQISTENFLFYAVSPKIKDFGTFPVRAFAEIPNK
                     L"
     misc_feature    complement(21646..21661)
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 26.05"
                     /tool="antismash"
     gene            complement(21894..23180)
                     /locus_tag="J2M30_RS22685"
     CDS             complement(21894..23180)
                     /EC_number="2.7.1.-"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016301 - kinase activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019394135.1"
                     /locus_tag="J2M30_RS22685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="four-carbon acid sugar kinase family protein"
                     /protein_id="WP_216701212.1"
                     /transl_table=11
                     /translation="MGQIIGVVADDTTGANDIGIMFSNKGYKAKVQIFEEEMNVKGDAD
                     VVIVDTDSRLDLDNLSYQKVYGATEKLQETGCSMFFKKTCSVFRGNIGKEFDAMLDALG
                     EEFAVISLAFPKNGRTTIGGMHTVYGQPLEYSAFANDPVHPMKESDLVSILQKKTLRKV
                     TFVDLSIVRQGATVLRRTIEEIRKHFNYCIIDSETQSDLTIVAEAIHDYKILGGSSAIA
                     EELPKFLGKRSTHNLVTDLNIEDQNGVLVVSGSLTPQTRAQTAHLISSGVPYKVFDSRK
                     VFSPVEYDKEVMRVSLESQKLLIQGEDVLIMADNNKDIILETKEMGKKLEIDPLSISKM
                     VSAAISDITKVIVDQVDLKRLIVAGGDTAGTVSRKLDIKGNYVLKEIETGLPSGLAIGR
                     HMLIVLKSGSFGGEEFLSLAIKHLKNLSR"
     gene            complement(23203..23871)
                     /locus_tag="J2M30_RS22690"
     CDS             complement(23203..23871)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019394134.1"
                     /locus_tag="J2M30_RS22690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="class II aldolase/adducin family protein"
                     /protein_id="WP_040057459.1"
                     /transl_table=11
                     /translation="MNYKQQLMNTGKYLISNQLAWGTSGNISVRTDPDEMLITASGTYM
                     ANLSEDDFVKFNISTGQNYSERKASKETPMHLGIYQKREDINAVLHSSPFYTTLFSCSN
                     EAIISKLFVETMYYLEDIAYVDYFHPGSQELAEAVTAQASNANIIIMKNHGVVVLDESL
                     LEAQMRLQTLEMACHMILKAKESGIKLSLIPQKTVQSFLNESFYKPRKTVNHSIKPSNK
                     "
ORIGIN
        1 gaaaattcta agagatcacg cacatgaatt agcaggtgtt attctagaac caattcaagg
       61 tggttttatc cctgctaatc aagattttat gacaggtctt cgcaaaatta cagaaaagct
      121 gaatattgta ttaatcttcg acgaagtaaa aactgggttt agattatcac ttggtggtgc
      181 acaaaaaatt tatgggatta aaccagatat tacagcttta ggaaaagttc ttggtggtgg
      241 tttccctata ggagctattg gtgggaagaa agagatgatg atgattagtt ctgctagaga
      301 tggtcgcgac attttaacag caggtgcaga aaataccgat aaacaagacc ctctatatca
      361 tagtggaaca tacaatggtc atccaactat actttcagca ggattagcaa cgattaatgt
      421 actagaacaa gaaggtacaa tggacaaatt atttgcaaga actcaattac taagaaaaca
      481 gttagaggaa atctataaat cttatggatt aactatgcaa acacttggca tggggagtat
      541 ttttaatatt atccttggtg aaggagatat aagaaattat cgtgatatga gcaaaactaa
      601 tacaaaatta cgaaaacaaa ttgattatga attgttgaag ttaggtattt atacaaaacc
      661 acttaatcgc tactcaatgt cagtagtgca cactgaagaa gatgtacatc gtacagtagc
      721 agcacatgat gaagccatca aacgtgtttt aaataaataa gcgttcttca ctaaagctaa
      781 agaaggaaaa atagagctat aacaggtgtg tatccttaca cctctttata gctctatttt
      841 ctattcaatg agtacaatca tctctttttt atgaaaaaat attagaataa gtaaacagat
      901 tgttaccaac accttttaga aaaaattaaa ggctatatac tataagataa tcctgaaata
      961 tgtttcccct ttaaaataag agaagaatta gcttctagaa ataatatttt aaaatctcga
     1021 attcacctta ttccttatat aggtttgcta cacatttaga atgatataca atctatataa
     1081 gatgagtatt tttagtttat aatcttaact atatccttca aactaaagcc ttaatatagt
     1141 ttataacatt aacaaaataa ggagattgtc taaacctatg gaaaatatat atatacacat
     1201 cgcagagcaa atgcctagta tgagtaaggc aaatatgaaa atagctaaat atattttaga
     1261 aaaccctaat acagttccct ttttaaccgc agataaatta gcaaaaatca caaaagttag
     1321 ccatgccact gttgtacggt ttgccacttt tttaggttgt tctggttatc cagagttaca
     1381 acaatatatg caaaattctg cgcaacaaca gttgacaaca accgatagat taaaaatttc
     1441 taaagaggtt tacaatgatg aagaccaagg aatatatgat atctttttag atgatatctc
     1501 aaacataaaa tcaacttttg agaaattgga catcgatatg tttaaacaag cagtagacag
     1561 gcttatacag gctaaaagag tgtatattgt agcgaatcga agcgctacag ccttaggcgt
     1621 atttttacaa tactactttc aatttctctt agataaagtt gagctgatac actcaataga
     1681 aacagtgtca gagcgtttgt atgatttgaa taaggatgat gtagttattg gcattagctt
     1741 tgcgagatat acgaaaagca ccatacaagt tctagagtac gccaaagaaa gagaagcttc
     1801 tactatagca ataacagata atcttttatc acctcttatc ccatacgcag acatgccatt
     1861 aacagcatcg agtcagatgc ctacttttat cgattcattt gtggcacccc ttagtttaat
     1921 aaatgccctt attatatcag tagggagagg aagagaagaa aaattccaaa ataaattaga
     1981 atctcttgaa gaaatatggg agaaattcga tattttctat aaaaaataat ctttaaatgt
     2041 cttacaatta catagtgaat aagacaaagc agattcatga agtatgaaag cacgctttgt
     2101 cttattacat tttaataaat gtacttaaaa accatcaaag attttgtaat tcaattcaat
     2161 ctaattcttt ttgtcttttc tttttaaaac gttctcttat tatcgataaa aaatatgttg
     2221 tatatgatat gaatttctag tttggataaa acttcttcaa taaagtagta aaagctcaaa
     2281 ctcgttgcca ttcaacaagt gtgagctttt tctttccctt tagttatact tttaaggacg
     2341 tgaattaaat gaaaaaatgg ttacccaagt taaataccgg tcttttcatc ttatgattat
     2401 tcattatgat taaaaacgat tctcaaattc ccttttactt tcccgttcct taaagtacgt
     2461 aatctaatgt tttgttgttc gttcataata cattttaaat taaatctgat taccgttttt
     2521 ccacgttata tcgtaaagtt cttttccatt acttgcccac ttattagcta tgtacaccct
     2581 ttctattcat gccgtttcat catacttatt tttaaaataa atttccatct tatcaggatc
     2641 agcaataaga tgattttcgg tttatgcaag ttatacttta tttagatgat ggagagatga
     2701 cgattttaaa catgtggttt ttttaaagct actccaataa tataataggc ccaacaaaag
     2761 atcagtctta tgaagagtat taaaagaact ataataagtt tttctgttat aaactctcat
     2821 ttcttgatgg tttaccgaaa taggagtaac actccaatct tcaaggaaat aacttctaaa
     2881 gattatatat tagatacgct gggagtgaaa gaggatacta attttatagg aatagcgtca
     2941 ggaaaatatg gatttacaac tttaaggaaa attcaatatt aaaaagccta atttctcaat
     3001 ttaatgcgaa gaaattaggc ttttttcctt aattcattaa agcgcccttt agtagaaaat
     3061 gggtgcgaga atcagcattg gtactgaaca gaaaatcata aaaacactgt tagtctctta
     3121 tattgactta ctactattgc taatcctata gattaggtac aaaatgacca aaaagaagaa
     3181 gctgtttcca ttaaaaaagg cgacttagaa gttttattta aagctttact tctacctcag
     3241 ttccatcctt caatctcgtt tcaacaagga taactccact gtacttagaa aatccttgca
     3301 gcaacagctt caaatctttt ctttcaattt ccgggaatat gaatttgctg ccgtcttttt
     3361 caattgcttt atttattaag cgattaatcc tttttgatgt aacaatcaaa ctaaccaaat
     3421 ttaaaaccgt atagggaaca ggaatggaaa atcgtttatc ctttactttc accttgactt
     3481 ttaacataat ttactcaatc accacgaaga ctttatcacc cttggatgag gtgatgtcaa
     3541 caatctgtcc gtccaattca ttttcaattg cttcaatgag caggtcaatg ttaatatctt
     3601 ttacatattt ttctgcctca ggtatttttt cagcaatgtt tgtccctact ttcaaaacag
     3661 cctttaccag attaattggt aaattcacat ttacattatc tccttcttca gagctcacac
     3721 gaatctttaa cattttattt ccgtatggga cttctttatt tattgtcact agctctggct
     3781 gatctttacc ttgtaaaata ttaattaatt cacttgcttt ttccttatca atctttcctt
     3841 cctccactag cgttaagact ctcgaaattt cgtccttcat tatacttccc cctcttttaa
     3901 taactgaatg gctttctctg ccgtaatttc gcctttttcc aatagcgata caattttttt
     3961 cttatctact tccggtttct tttgagagga atatcccagg gtagagataa tttcatctaa
     4021 ttttcctctg acagtcggat aggaaattcc aagttccttc tcgacttctt ttatatttcc
     4081 acgacattta agaaaaattt caataaaatg cagctgttcc tgaccgagag ccgccagtct
     4141 tgaaacttca aattcgtttt ctaccgttgt ctggcaatgg ttacactgta gcttagtaat
     4201 tttaagcgcc ttcgtgcaaa ccgggcaatt agtaagtaaa ggatatgcca tactgttctc
     4261 ctttctttca tttaatcata tcatacacta catcttttaa ttttaaaata aatatttaat
     4321 atttttataa aaaaacacga ttttatttaa taaatcaaat cacaaattaa ataaattaat
     4381 tttccaacgc gtgatttaaa ttaaaaaaca gactcattag agagtctgtc tgattgtcga
     4441 gaaagggata agaacctatt tgacacttaa agaaaggttc ttcgatctat agtgatttca
     4501 ttattttaga acattttctg aaacttttgg aagacacttt tcttcataac aaacattact
     4561 attttatcaa gaaaatcaag accataaaat taaaacaaga tgaaatcgaa aaagagtttg
     4621 tgtcgtaagt aaaggagagc ttcataacgc tctccttttt attttaataa atataagaat
     4681 aaatcaacct acaatcgtca attggtaaca acacatcaac aaggcatttt tcttaataaa
     4741 atcacttaat attttaaatt tccgttatct taccaattgc aaatttaaac tttattttgc
     4801 gtactttttg cattttactt tgtagaagga ttaacaccct gtccggaaaa ctaggatttc
     4861 ttatatcttc ctattttttt ggacagcccc ctttttccac cagtttaaga aagacttact
     4921 gatcctctga ttctacctca aggctttcca ctttattatt ttttttaact tctagacgca
     4981 ctatcttacc ttgaatatct tgagatttat tgtcaacatc cttttcaaaa tcatttgctt
     5041 ttgtataagt ttttttacca ttatgtactt ctatcgtgac ttcattactt gtttcattaa
     5101 ttagctttcc aattacgttg taatctccat ctgattcttt ttcgtaaata ccctcatcat
     5161 tagctttagc ttgaggggtt aattctaagc tttcagcatt ttgacctttt gtgtttacct
     5221 caattttcac caattcccct tttatgtccc catttatttc atcctctttt tcaaaggtat
     5281 ttctttttgg tattttgact ttttcattat caatgataag ggttaattcg tcttgtgttt
     5341 ccttatccag tgttcctact aaatcaaact cttcatcttg attaccattc ttttcgggat
     5401 acttagtgta tttctgtaga tttgtttgtt tttgagaggt atcagtgtta atggtaggag
     5461 atttttcttc actagcacat ccagaaagac tgctcatagt aagagccccc actattgaaa
     5521 cacatagcac aacggttttc ttattcatat aaacttttcc tccttcgtct acttatgatt
     5581 atattgcccg tctggctagt aaataaacaa aaagaggttt aaatcaatag atacgtctaa
     5641 caaaagtgca atgaatctct aaaactcctt atatcttcat taaattggtt tattgaaaac
     5701 aaaattcata ctctatggtg aagactgttc aatttaagaa gtccagaagg aaatattttt
     5761 ttattgatga gttttgaaaa gatgttttac gtaaaatata ttccagacaa aaaatcaaag
     5821 agacctatta tttagtccta actacatcgt tcttacctct acattattag aaatgtaaaa
     5881 aacgatagta agatagaggt gataaacata gcaatcagtg gcttaaaggc ttttgttcgg
     5941 agatctttta aacttacgtt taatcctaat cccaccatag ccatagttaa aataaaggtt
     6001 gttagacctg aaatatcatt cataatattc ttagatataa taatgtactt tcctagaaca
     6061 tagcttccaa aaacactcat cataatgaat cctattaaaa accaagggaa ttcaattttt
     6121 gtatcttcct gaacttttcc cgtacgtttc atccaataca ttaagataaa acttaatgga
     6181 acaagtagga agacccgacc taatttcgct aatagaccta ttgctaaagc atcgcgtcca
     6241 ccaggagctg cggctaaagc tacatgtgca atttcatgta gtccaacccc tgcccaaatg
     6301 ccatattgaa catctgtcaa tccgatataa ggtcttaaaa ttgtatatcc aatagcaaat
     6361 attgtcccta ccaaagcaat tataccagcc cctatagccg tatctttttc ttttgctttc
     6421 aaaatcggag aaacggctgc gatagcagct gctccacaaa ctcctgttcc aattcctaaa
     6481 aggagagata aagaagcatc tgcctttagc catttagcaa ttaaaactgt taagaaaatt
     6541 gaaaaaacaa tggttcctac atctcggact agtagaccta atccctgatg aatgactaca
     6601 tcaatattta actttaaacc aaataaaata atagcaaaac gtaatagtct cttggaagaa
     6661 aattcaactc ctgagcgtat actttcagga tacccccaca tctgacggta aattacagca
     6721 atcacaatag cacaggcaag ttgcccaacg tgattaaaac caggaacttt agccaatcca
     6781 taccccatta atgcaataat aaaagtaaac ccaatgccca caaaccataa ggcaaaagaa
     6841 gagagtttct taacttctgt gcgtaataac attgtatttt tttctttagc tgtcatattc
     6901 ttatccccaa tactaattat ttagttttaa actaaataat ttatttatac ttttactata
     6961 aaaggagata aaacattagg gaaatataga taaattatct taatgattaa taatgttaat
     7021 cgttaacatt aggggagagg aactagggta tttttatcaa caagcaattt tacatcacga
     7081 atattgttct atgctactta gaggatttga ccaagttttt acccgctgcc aaaagacaac
     7141 agtctttctt tctaaaaatt cattagggta tgcctaggag taacattccc ctcccccata
     7201 aagactcacg tgcacggtct gtcgttataa ttttatcttt aattgaagac tgtcaaacta
     7261 acttacacat catctttaag aatctcaatt tacacttcta catataaaaa aataatttga
     7321 gacttcttct acacaccata atttcttagt ttaagataaa gcctcttcaa gaaactaata
     7381 aaagctcaaa cacgttgaat gccaacgtgc ttgagctttt tcttgctttt tacatatact
     7441 tttacaaaag tctagcagct caatgaatat ttatctcttt taggtgttag agggttagat
     7501 catttttatg ttttagataa aaagttttta aaaatgcttc atcatgaatt gctttcacaa
     7561 aagattctac tgttttacct ttattcacag gacaaacctc ctcgtataaa accaaatatt
     7621 atacaggata gacggggtgc ttacgctcag aaaaaattag gtattttgaa gaatatgctt
     7681 caaagcgttt agttaactca tcgcgtagtg agtttgccgg aatgactcca tcaataacca
     7741 tttctgaagc aagccggtaa atatcaatat cttctttata ttccgcacgc ttttcagcaa
     7801 taaatgcagc cttctcttct tcaggtaata cagcaatttt gttggcatac acagcattga
     7861 cggctgcttc tggtcccatc acggcaattg aagcggaagg tagagccaaa caagcatctg
     7921 gttcaaacgc cgggccggcc attgcatata gacctgcacc gtatgccttt cgaacgataa
     7981 cagatatctt gggcacagtt gcctccgcca tcgcagaaat catttttgca ccatgtcgaa
     8041 tgattcctgc ccgttctacc tttgtgccaa tcataaatcc aggcacatca actaggaaca
     8101 ataacggaat atggtatgca tcacaaagat taataaattt cgcagctttg tcagcactat
     8161 catggaatag cacgccaccc tttacacgag gctgattagc tatgatgccg atcggttttc
     8221 cgtccatacg ggcaagacct gtaataagct cggtagcaaa taatttctta atctcaaaga
     8281 aagaaccttc atcaataatt ccattaataa ggtcatgcat attaaaggga gagttttgat
     8341 ttgccggaat cagctcttcc aatgatttct tcatttgttt aggtgctact gcctcatgaa
     8401 ctggcggctt ttctgaaaaa tttgccggaa agtaagaaag ataattgcgg gcaatggaaa
     8461 tagcttcctc ttcattttta gcgagtacat caccgcaccc tgatactgaa caatgcatac
     8521 gagcgccgcc catttcttcc aatgtaactt tttccccgat aaccatttcg gccatccgtg
     8581 gtgagccaag gtacattgat gcatttttat ctaccatgat aacaatatcg caaaatgccg
     8641 ggatataagc cccacctgcg gcagatggac caaacagaag acaaatttgc ggtacttttc
     8701 cagatagttt cacttgattg taaaagattc tgcctgcccc gcgacgccca ggaaacattt
     8761 ctacctgatc tgtaatcctt gctcctgctg aatctactaa ataaattagt ggtatacgaa
     8821 gtttctcagc tgtttcttga attcgaatga ttttttcaac cgtccgtgat ccccaggaac
     8881 ctgctttaat agttgaatca ttagccatca cacaaacaac ctggccatta atcttcccca
     8941 ttcctgtcac aactccatcg gcaggaagtt cccccgccat gcagtttgca aatagcgcat
     9001 cctccagttc aaagccagga tcgaataact gttttaaacg gtcccgaaca aaaagttttc
     9061 cttgttctgt gtttttttca tgatacttaa gagcaccccc ttttttaatt ctttctactc
     9121 tttcttcaag tatttgttgt agaggtttca tatccattgt ctttcctcct ctattcattc
     9181 cattttttta ttctccaata tatatggggg ttcttttttc cttaaaggcc tgtaagcctt
     9241 ctaaacgatc cttcgatgga atcgttactt cataggcact ttgctcaatg gcaagaccgg
     9301 tgttcatatc aacatcatag cctttatcaa tggcgaactt tgcttgcgcg acggcaattg
     9361 gaccatttcg gacaatttgc cctgcgattt ctaaagcttt tttaatcaaa tgatttgaag
     9421 gggccgtatg ctctactaac ccaatttcta aggcttctgc tgcatcaata cgtctcgctg
     9481 taaaaataag ttccttagcc cgtccttttc ctactaatct cggtaaacgc tgcgtcccgc
     9541 ctgcaccagg tataattccc agcgaggtct ccgttagacc aagcttcgct gtttcagaag
     9601 caatacggat atcacaagct agcgcaagtt ctgttccccc acctaacgca acaccattca
     9661 cagccgcaat aattggctgt ggtaatgatt ctaaatcatt gatattctca cggatcaaag
     9721 caagcgtctt ccgtacctga atctggtcca tatctgcgcg ttcttttaaa tcagcacccg
     9781 cacaaaaggc cttttctcca ccccctgtaa tgactacaca acggattgtc cggtcatatt
     9841 tacataatag aaccgcttct tgaagttccc ctagcatttg aagagataaa gcattagccg
     9901 cttcagggcg atttaatgta atcattacga ttccgttttc cagcctgtta actaatatca
     9961 ttttattcat attttcacct tcctcacacg gtattaatgt ctattgggag gttgaagctt
    10021 gaagactttt actaggtaaa ggtctcccaa tcttcttctg aataaattgg gatgcagata
    10081 aaagcttttt ctgatccacc ccagtgtgga tttccattcc gtgaagcata taaagtaaat
    10141 catcagttgc cacattacct gatgctccag gcgcataagg gcatcctcct aatcctccaa
    10201 tggaagaatc aaaagtggta atacccattt ctaacgatac taagacgtta gctaaggctg
    10261 ttccccttgt atcatgaaag tgcatcgcta atttatctgc cggaaatctt ttcaagaaaa
    10321 cttccaataa ctcttggacc tgctttggat tcgcaacacc aatcgtatct ccaagtgaca
    10381 gttcgttaat ccccatctca aataaggttt ctgaaactct tataacctca tttatatcga
    10441 taggcccttc atacgggcat ccaaaaacag tagaaacata acctctgctg ggttttccta
    10501 ctgcaagggt tttttggacc agatttctta agatagggaa tgtatcgcta atcgatttat
    10561 taatattttt tagattatga gtttcgctgg ttgacataaa tacagctact tcatcaacat
    10621 ttgcttcaaa cgcccgttcc aaaccttttt ggtttggaac gagagccgta taggttacac
    10681 ctggcacttt tgtaatgcct gtggcaaccg cagtggcatc tgaaagggta ggaatccatt
    10741 ttggattgac aaaggaggta atctcaatcg attttaatcc gctagcagac aattgattaa
    10801 tcaaggaaat tttatcttct gttgaaatga aatccttttc gttttgcaat ccatcccgtg
    10861 gaccaacctc tttaatggtt atattcttgg gccatttcat tgctttatca cctttcttcc
    10921 gatgatttta ggacttattc aacttttaca ataatgtctc cttcattcac aaattcaccc
    10981 tcgttcactt ttacttcttt aacagtccca ccagattcgg ctgcaatcgg aatttccatt
    11041 ttcattgatt ctaaaatcac tacatcttgg ccttcttcta cttgatctcc aactttaaca
    11101 agtactttcc acacatttcc tgccatgctt gctacgattt cactcatcat tattcctcct
    11161 ctattccgcg ttatttgttt ttttagtttt taaatacttt ccaacaaagt ccgttgtcgt
    11221 atcacctgaa cgaaatgccg ggtgggcaat gacttctttc agcattggta tatttgtttt
    11281 aattccttcg atatgataat ccactaatgc cccgtgcaga cgatttattg cgtcgtcacg
    11341 atcattccct tttacaatga gttttgcaat cattggatca taaaaaggcg taactacaga
    11401 ttgatcatga accgctaatt catgccgaat tccagatcct tttggcaatt ctaatttggt
    11461 gattttccct ggagaaggaa aaaatgtttt tggatcttct gcgtagattc tgacttcaat
    11521 cgcatgacct tcacgcttta cctcttcctg agaaaaatcc agtgcttcat cccctgcgat
    11581 tttcaattgt ttttccacta agtccaaacc tgtaatttct tctgtaactg gatgttccac
    11641 ctgcaaacgg gtgttcattt caagaaaata aaaattttgc tcttcatcta ctaaaaactc
    11701 aattgttcct gcatttttat atccaattga ttttgccgct tttactgctg cctcccccat
    11761 ttttctacga gtagtttcag aaagaaaaga tgacggagct tcctcaacga ctttttgatg
    11821 gcgacgctgg attgaacatt cacgttccca tagataaacg gtattgccaa aaccatctgc
    11881 caggatttga atttcaatat gcctagggtt ttccacaaat ttttcaatgt acatggtacc
    11941 atcgccaaag aaatcagtag cccgtttttg attccccgca aacgctttgc ggatttcatc
    12001 cccgctatgg acaacctgca tcccgatgcc gcctcctcca gcggaagctt ttagcattac
    12061 aggataacca ataaagtcag ccgcttctac cgcttcctct gcatcagcaa gaggataggt
    12121 aatcccagga accacaggga ctcctgcttc ttccatcgct tttcgtgatt ggatcttgct
    12181 gcccattttg gagataacct ctggagaagg tccaatgaat atcaggcctt ccttcccaca
    12241 gcgccgggca aattcggcat tttcggaaag cagaccgtat ccagggtgaa tagcctgtgc
    12301 ttttgttaaa cgggcgactt ctaaaatctt atcgatgttt aaataacttt ctgctacacg
    12361 cgaacctcca attaaatggg cctcattcgc catttttaca tggggagcgt ccgcatcagc
    12421 ttctgaatgt acagcaactg taataattcc tagggccttg catgtccgaa ttacccgaac
    12481 agcaatttca ccacgattag caatcaaaac ctttttgaac atactttccg ccctttctac
    12541 cttttattta ataggacttt tcggtatcat catgaagctt aaagttttat gttatggaga
    12601 tatgtgaatc tatttatagc ttcatcttta actaccaatc tagtgattac aaagaaaaag
    12661 attaaatgga atgaggcatt tgccgatcat tttatgaaca aatgaccgac ccgaataaag
    12721 cattatatag ctgataattt actagcaacg atcttctgga tttctacaac agttgatggg
    12781 tcttcaagcc ctgtaatgtc accagctacc tttcctgttg ccacaatttc ctttaataaa
    12841 cgccgcataa ttttcccact tactgttttc ggtaacatat tagtcataat tattgctttt
    12901 ggactggcaa tcttaccaat ttgttggatg atactcctat ttatccgttc tatcatctct
    12961 tcattatctt caaaaccatc agctagacga gcaaatacta aaggaacttc cccttttatt
    13021 tcatcaggaa tcccgatgac agcgcattca aaaatacctt cgcattcaag tacagcactt
    13081 tccatttcca acgtacttaa tcgatgtcct gccacattaa gcgcgtcatc agaacggcca
    13141 accacccata tatatccatc tttatctatc aatgcaagat cgctggcata ataacttcct
    13201 tctacttggc taaaatagga tgcgtaatat cgctccggtt ctttccaaag tgtacggcac
    13261 agcataggaa atggttttct aattactaag tttcctaact gaccagattt aactggattg
    13321 ccttcttcat taacaacatt aaaaactgca cctaaaaatt gagtccctgc agaaccaggt
    13381 ttcattggcg tcagccaggc tgcgcctgcg ataggagatc ccgctgtttc cgtttggccc
    13441 caagtattat tgatatatac ctttttcttt cctaaaactt catatgtcca atgccatgtt
    13501 tcagtatcaa aaggttctcc cacaagagaa atgacatcaa gacaagataa atcaaattgt
    13561 tctagtggtt tttctcccat actttttaac attctcaatg cagttggagc agtaaataac
    13621 ttattcaccc ggtatttttc aataatttga taaaagcggt tcttttctgg ataatcaacg
    13681 gctccctcat agacaacggt tgttacacca tttgctaaag caccagtaat accccaaata
    13741 tgcatcgtta accacccaat atcagcagta caccagaaaa catcatcatt gtggtgatcc
    13801 atatgatact tggcatatgt gtaattttga ataacaaaag ccattccaga atggacgaca
    13861 cctttaggtt ttcctgtcgt accacttgta tagaatacaa tccctccctc atttgcttct
    13921 attctctcag gttcacaaac gatgcttgct gtttttgtaa gctcgtgcca ccagtaatca
    13981 cgcccttctt tcattggaac ttctaaacct aagcggctga caacaatgac tgcttcaaca
    14041 gatggaatag ttggtacaac ttgatcaact ttttctttta atcgaatagc tttaccccga
    14101 cgttctgttg catccgcagt taccactatt ttgggttcaa aactgatgag acggtctttc
    14161 aatgactttt cggaataacc tgagaaaata gtgttgtaaa tagcaccaat acgaaaacac
    14221 gctaacacgg caatacatgc ttcggccagg tttggaagaa aaatagctac acaatcacct
    14281 tttttcaccc caaatgaacg aagaacattc gcaaatcgat tcacttttgc aagaagcata
    14341 ttataggtat aaaattttgt gtctccgttt tcaccctccc aaatgagagc tgtccggtta
    14401 cctgctccat tagctatatg ccggtcaagt aaattgacac ttgggttgct aatgccgtcg
    14461 acaaaaaaac gaaaatcagg gagttgtcca ctaatggttt ctttccaagg ttcataccac
    14521 acaaggtccc gggctgcgct atcccaaaaa gcagcaggat cttcttgaga ttgtcgaaga
    14581 agttcttgaa aagcttctat gcttccaata gaggtagagc gtaccttttc tttattagga
    14641 aaaataagtt tactgtttgc aactacttgt gaaattccat tgatatccat ggagttactc
    14701 ctttatcttt ttttgaaagc cgttacaaaa atgaatctag catcctattt gctttgcaat
    14761 taccatacgc tgaacttcgg atgttccttc cccaatttct agaagcttcg catcacggaa
    14821 gaatcgctca acttgatatt ctttcatata tccataacca ccatgaattt gaatagcttg
    14881 atcacatgcg cgcatgcata tttcggaagc aaataatttt gcgtatgctg cctctttttt
    14941 aaatattcgg ccttgctcct tcaaccaggc tgctttgtaa accatattcc gggcaatttc
    15001 aatattcatt gccatatcgg ccaatttaaa ttggattgcc tggaagttcg atagactttt
    15061 tccaaactgt tttctttctt tcgcatactg aagtgatttt tcataagcgc cctgtgcgag
    15121 tccaacggcc attgccccaa ttccaattct tccaccatca agggtcgcta aaaattgctt
    15181 gaaaccctct ccttctgttc ccaacagatt atctttagga acccttacat tttccaagat
    15241 taattctgtt gtatttgaag attgaagacc cattttttcg taattattga taacagtaaa
    15301 tcctggtgcg ttcgttggaa cgataaatgc gctaattcca ttaattcctt ttgagcgatc
    15361 tgttacagcc gtaacggcaa gatgtttggc atagcttgca ttagtaataa aacattttga
    15421 gccattaatg acccactcct ccccatcaag aactgcagtt gtttgtgttc ccccggcatc
    15481 ggagcctgca tttggttcag tcaaaccaaa tgccccaaat gactctcctg tacaaattgg
    15541 cgttaagtat ttctcttttt gctcatgggt accaaacaaa ttaagaggtt ctccccctaa
    15601 tgaaatatga gctgaatatg tgattcctgc tgatgcacaa acacggctta actcttcaac
    15661 gacaatggca aagctgatcg tgtcagcatc accaccaccg tattgttctg ggaatggaag
    15721 gcccatgatt cctaactctg ctaattttga aaacatttca taaggaaatg ctcccgtccg
    15781 atctcgttca tctgctccag gagcaacttc tgcttccgaa aaatcccgaa ttaacttacg
    15841 tatcatctct tgttcttttg ttaaatcaaa attcattttt caacgacctc catttattgt
    15901 cgtaacattc tagttattat tgatgaattt ttccaccttc aaaaatatac ataatcgact
    15961 ttccttttta ataattatca aaataacaac aaaactctat gcaccgaccc cctttcgata
    16021 ttttttaata tttataatta tcaatattaa aaaaatataa atctatgtat acttctatga
    16081 aaaatttgtg tgttttacac caataaacat aaatgtataa atatattaag ttctaaaagt
    16141 aaggatgata aatgaggcaa gatacattaa ctcacctgaa actaaaattc ctcatccctg
    16201 ttccaaacgt tataaattct tccttagata ttaatacgat ctttgattct atcaataaat
    16261 gaaatgattt ctatcataga agttacagac ggaaggtcta tttggatatt tgacaaaaat
    16321 caaaaatgat taattgtgga gtcatcttat tgattatttt atctacatat ttttaaatct
    16381 attaaactac atagtagttc attaataacc agcatgactt tgaatacaaa aatgcatttt
    16441 cggaataaca aggaaataaa acaggttcta gatacattaa ctttatataa taaagactta
    16501 ttagacagat caatatcaaa caactttgat tttatacctg tcatttcttc tcccctttta
    16561 caaaagggta agtatgaata aattttaaat attttatatt tttcatctga acgtatatct
    16621 atgttacgat catgtacgag tctatttata ttgataaatg ggtattgtac aaaaaaagga
    16681 ggaaatatag aatggatcat gtgataaaac cagcgggatt ttggatacgc cttttaggca
    16741 acctattaga tggtgtaatt gtcagtattc ctttaaccct cattgttttt ttacttacag
    16801 gagaagtcaa tgaaaatgac cctgttatct caattttagg gtttatctat accgttgctg
    16861 tacctatttt atggtcaggg tatacaattg gaaaacgaat cgttggtgtt agaattgtaa
    16921 aagtaaacgg aaagaagctt ggaatcggag cgatgctatt acgggttctt gtagctggaa
    16981 ttgtttatag tcttacgtta ggtattgctt taattgtgag tctttttatg gttgttttcc
    17041 gtaaagataa gagaagtctg catgatttaa tggcaggtac ctatgttaca tatgcaaaac
    17101 ctcacgaaat ggaagataaa catacagttg caagttaagt aggtaccaac tctaagtatt
    17161 acaaactgga ggttttcacc ttacttaatc tgtacaattc tgattcaaat ttttacataa
    17221 gaacaccaaa aaataagact ccctcacaga caaagggcag tcttattttt ttgatggcgt
    17281 atattcggaa ctaaccaact taaaatccct aggcgctcaa gggatctcat ctttatacag
    17341 ataaaaaaag agaaaggtaa aaagtgactt aatactttaa tatgactgct tcctttatta
    17401 gtcgagatta tatgaactaa gaaattttaa aaataaaaat cactttatgc tgctggatat
    17461 aaacattgaa gcgtcttgat tcataaagat atgattacca tgatagaatg tcgtaatttt
    17521 aattgattta aatccaactt ccgataatgt ttttttcagt tcttcatgtg aaaaaccgtt
    17581 gtgaactttc ggatgattta tcttatgatt tttatcaaaa tcaataacaa ctagctttcc
    17641 ctcatcattt aaaacgttaa acaattcttg taaaattttt ttagtatctg gaatatgaag
    17701 aaggactagt gacattaaaa ctatatctgc tttgaggtca ggagttcctt gagtaaagtc
    17761 tgaataaagt accgttgaat tagtaatttc tttttgagaa attttagctt ccgcaacctc
    17821 caacatttgc tttgatgaat caaccaacaa aatagaatct actaaatctg ataattctaa
    17881 accaattaga ccagtaccac tcccatagtc tattaaagag cttgatttac tattttgtaa
    17941 ttctgttctt acttccttaa ctataatttt agctaattca attctttctt ctgtatcata
    18001 tctttttgct atctgttcaa aaacattatt ttccatatct cactctactt tcctctttat
    18061 taaaagctag atctacatag tgatcattat atcaaaaaaa caaaaatttt aaaaatcaca
    18121 aaatagttaa atcatgtaca gtaaatacat ggctttcatt ttatacaaaa gaattcagca
    18181 tgaatggtgt aaaagacgaa aacatactaa aagaaacatt atcgttgaat aattagcaac
    18241 gggcatgaaa aagttgattt tgtaacaaag aaatcaagtg aagatgaaat tgagaatttg
    18301 cactaaaaaa atgataaagt aatctaattg ttcttctata aagtagctat atgtatcata
    18361 tacattagat taaattattc aatgtaccac atagtgccat tgaacaccta tttttagtga
    18421 gtagaagaac ctactacata tagtagtagg ctttcctgtt catgaatgta taagatatcc
    18481 aaatttagtt gttaaatttt aaccatataa gcgtttattt aaagtattat tactataaaa
    18541 aaatataacg tttacataat gttggtaata ggtagaaaaa tcttattagt atcaataagt
    18601 ttaaaatatc gtaacttatt ttcaaacaac atattttttt ataaacataa cgactttatt
    18661 ttaaatctac agtagaagat taaatgttac agtaaatagt cctttaaaga ttgctgtagt
    18721 gttccttttg ttattgcctt ttgattgaaa ttaatgccaa ggtgaatcat ctctctcacc
    18781 agttctggtc tcaatccggt aataactgac ttacacccca tcatattaat tccatccagc
    18841 actttatgaa aatgatcgat aacaaccact tccatatccg taatacctga taaatccata
    18901 attaatgtat gaatacgggt tcttgcgata tcagttagta ccttttcttc aatcgtgtcc
    18961 attcgatacg aatcaatggt tcctattaaa ggaagaatgg caacggtagg actaattggg
    19021 ataataggta cagatagatg ttccacattt tttctttgcc tatgaattaa ttcgtcttta
    19081 aaatctgaat agcttaggaa aaatgtattt agaaactgat caatgttgtt attgattcgt
    19141 tcctctaact caaaaaaatc ttctctaata ctaggtaagt taaattcaga ttgatattca
    19201 taaattgttt tccataagga tcttcttatc gcctgaaccc attcaagttt aaaagctaaa
    19261 gtaagcgaat attgagccca agcgacccct tcctgtttag caaatacaac aatatcttga
    19321 tcattgtttt ctaaaatata aacaactaat ctttcagcat tctttaagag atcaatatta
    19381 ccttgcttta gaatatcgtg aataacctct gcaacattta cggcttctga taacaacttc
    19441 tgttgaaaat cttctctctt agccttaaca tagtgaatca tttcttgaat atcattattg
    19501 ctattcctca ttgaatgtaa cccctttcag aacaacctta taatatcccc ctaattctgt
    19561 attataactc gaatatacaa gatatcgcta attctaaccg gcccctatag tagaaaaaat
    19621 cccgcttcct tacgacaacc actcttattg tacctttaac aaaggtttaa ctatataatt
    19681 atatatgcat atgaacctac gaaactgttc atcatattca tgtatttccc aaaacgaaaa
    19741 aactactgat taggcacagt agttttctat ttctatcttt ccttcataaa tttatatttt
    19801 cttttttgcc acctctgtac tttttcacca cgatagatgc tattggtaca cctacaatag
    19861 tgggtaaaaa ccaaaaccac aatttcggaa gtttatttaa taaagggagc atatctccaa
    19921 tgttaactaa aagggctgtt acagcaccga tataagaacc caacatacct ctaatatgat
    19981 gattaagcca atttccccac cgtcttttac ctgcaagata accataaatc gcaaaggaat
    20041 aagaaaaaaa agctacataa aacaaataag ctatttcttc ccatcgtaat atagataaag
    20101 taatggcagt aataaatact ccaacgtaag aagcatggta gacttcaccc cattttgtat
    20161 gaatccctct tcttttgggg gctgacatgg ctaggagccc gaaaagcaaa catattattc
    20221 cacacacaat gtgaatgatt aaaattatgt taaaaatctc cacaataact cctccttatt
    20281 ttatcgttag gagtagaaaa aacggctatt tatttgattt aaacgtacgt taatcaacta
    20341 aaatcatctt ctccatatga ctattatata accttaacat tttaaaaatt agtgcattat
    20401 ctcatcattg agatatgaga tttatcatat tatttttagt tcgcataatg ctgtttatca
    20461 ggatctatct ttatataggc aaaaggcatt taagaaacat cttaaatgcc ttttgcaatc
    20521 ttcatgttat ttttacttat cgatgataat agtatcagcg tttttatctt caaaacagag
    20581 atttatcgtt ctttgtttag ctctagtcct atgaacagtt ccagctggaa taagtattgt
    20641 atcatttggt tttaaaacaa cggtatcctt atctttgaga tcaattaaca attcaccttc
    20701 taaaaccata aatagttcat ctgaattaga atgataatgc cattcgtatt cacctgaaaa
    20761 aacggcaata cgaagacagt gattattgac atcagacacg gcaaaattca catgttgatc
    20821 tttaatatcc tttgtaatct ccagaagatt gatcttttcc aaatctattt tttctatcat
    20881 tttaattctc ctttgatttt taaggggatt ctaatataat aaactatgtt gtgtaactat
    20941 agtttatttg gaatttctgc aaaggctcta actggaaaag tcccaaagtc tttgattttt
    21001 ggggaaacag cataaaataa aaagttttca gttgaaattt gttttaagtt gcataaatgt
    21061 tcaacgatga aaatttcttt ccctaataaa gtggtatgta caggacgatc tttacctgac
    21121 gtattatcta tattcacaga atcaatccca actaaagcag cttttttatc cactaaatat
    21181 tgtgcagctt tctccgttaa atatggatga ttttcaaagt attgatctgt attccagtat
    21241 tggtcccaac ctgtgtgaat aaggacggct tttccttcaa tatcaaggtc ataaaacacg
    21301 tcttcattaa tctctttttt atttttatca atatgaatgg taactccttc tagaccagcc
    21361 atcttatcaa ttggtatttc cgatagatct ttgccattag catacctatg aaatggaaca
    21421 tcaatataag ttcctgtatt agacaccatt tctatttttc caatttgaaa ttctgttcct
    21481 tctccataat gttttcggga ttcttctcga cttaaataat cacaaatgat tggagcagga
    21541 agccctttat aagttataat gccatcttga atcgtatggc tcaaatcaat atattttttt
    21601 ctcttcatat tataatcaca ctctcctttt atattaataa aagcggttta catatggaaa
    21661 ttttatcata tttttctttt tagaatgtat attatataaa cctaggttac ataaaacttt
    21721 tcaaggaagt aacaaaagca caaacccgtg attaacaaca agtttgtgct gtttcttttc
    21781 cttaatgtat acttttgtgg acggtaatta aattgaaaag ttcgaatatt atttttgaga
    21841 ttctgtacat aaagatatac agagaagaaa attactatct cctcttcttc attttagcgc
    21901 gagaggtttt ttagatgttt aatggcaaga gacagaaatt cttcccctcc aaaactacct
    21961 gatttcaaaa ctattagcat atggcgtccg atggctaatc ctgatggtaa acctgtttca
    22021 atctctttca acacatagtt tccctttatg tccaactttc tactgactgt tccagcagta
    22081 tctccacctg ctacaatgag tctttttaaa tcaacttgat ctacaataac ctttgtgata
    22141 tctgagattg cggcagatac catcttgcta attgaaagag ggtcaatttc taattttttg
    22201 cccatctcct tagtctctaa gataatgtct ttattgttgt cggccatgat taaaacatct
    22261 tctccttgaa ttaacagctt ttgagattct agggaaacac gcataacttc tttatcatat
    22321 tcaacaggtg aaaatacttt tctagagtca aaaactttat aagggactcc agaagaaata
    22381 aggtgtgctg tttgcgctct tgtttgagga gttaaacttc ctgaaacaac aagtactcca
    22441 ttttgatctt caatgtttaa atcggtcact aagttatgtg tagatctttt ccctaaaaat
    22501 ttaggcaact cttcggctat agctgaactt ccacctaaaa ttttgtaatc atggattgct
    22561 tcagctacaa tagttaaatc tgattgagtt tcgctatcaa taatacaata attgaaatgc
    22621 tttcttattt cttcaattgt ccgtcgtaaa actgttgctc cttgtcttac aatagataaa
    22681 tctacaaatg tcacttttct aagggttttc ttttgtaaaa tggatactaa atctgactcc
    22741 ttcataggat gcacaggatc attagcaaat gctgaatatt ctaatggctg tccataaaca
    22801 gtatgcattc ctcctattgt tgttctccca ttcttcggga aagctaaact aataacagca
    22861 aattcctcac cgagcgcatc tagcatagca tcaaactctt tgccaatatt tccacggaaa
    22921 actgaacatg tcttcttgaa aaacatagaa catcctgtct cttgtaattt ctctgtagct
    22981 ccatacactt tttgatagct taaattatcc aagtctaacc gactatctgt atctacaata
    23041 acgacatcag catccccttt aacattcatt tcttcctcaa atatttgaac tttagctttg
    23101 tatcccttat tactaaacat aattcctata tcgtttgctc cggtggtatc atcagctacc
    23161 actcctatta tttgtcccat tactatccct cttttctatc tttcatttat tactaggctt
    23221 aatagaatga ttcactgtct ttcttggttt ataaaaggac tcatttaaaa aactttgtac
    23281 agttttctgt ggaattaagc taagtttaat ccctgattct tttgctttta aaatcatatg
    23341 acatgccatc tctaaagttt gtagtctcat ttgagcttct aataaagact catccaatac
    23401 tactacccca tgatttttca taatgatgat attggcgttg gatgcttgag cagttacagc
    23461 ctcagctaat tcttgtgaac cagggtgaaa atagtctacg taagcaatat cctctagata
    23521 atacatcgtt tctacaaata atttagaaat aatggcttca ttactacaag aaaacaaagt
    23581 cgtataaaat ggcgatgaat gtaagactgc gtttatgtct tcacgcttct gataaattcc
    23641 gagatgcatg ggtgtttctt tggaggcttt cctctcactg taattctgac ctgtagaaat
    23701 attaaacttt acaaaatcat cttccgatag attagccata tatgttccgg aggccgtgat
    23761 aagcatttca tcaggatcag tcctaacgct tatatttcct gatgttcccc atgctagctg
    23821 atttgagata agatactttc ctgtattcat taattgctgt ttgtaattca tgaaaaaact
    23881 ccttttatga gataaacttt tagatggaac accttcaaca atttattagt tgtttgattt
    23941 tacagttata ctactgttca tgtagatgac atattatcat gatgcaattg aaatagctcc
    24001 tgtaattaag gcaaacacga ttaacatgag ggataaaata ataactggaa taagcgcata
    24061 acgttgaaat gctcctaaat ctctcctgat aagctctaat aatacccaca gcggggcaga
    24121 agttggaccc atagaatgta aaggctgccc aattactcct gcccttgcta tttcgatagg
    24181 atttattcca tattcagaag ccgattgagc cagaacaggc aaggcaccaa agaagaatgc
    24241 atcgtttgac ataagaaagc ttaatggcag actaattaat ccaacaataa tggtgaagaa
    24301 aggccctaag gattctggaa caatttggag taaatcagat gccattgaat ctaccatttt
    24361 tgtttcagat aatatccctg tgaaaattcc agctcctaac actaacatga caactggcac
    24421 agcatgacta gcattttctt taatcacgct tttttgttct gcaagattag gatgattaac
    24481 agaaagagcg attacaaaac ctataataaa taaaatagga agaggtgcta gacccaagat
    24541 tagggctatc ataagagcaa gcgttaataa aaagttaaac caaattaact taacattttt
    24601 aggaggattg tctgcaacag ttgcggccat ttcattgttg ctctccatac ttttattgac
    24661 tctttctaaa tgtataattc caatcctttt
//
