LOCUS       NZ_JAGKQT010000001     23546 bp    DNA     linear   CON 29-AUG-2024
DEFINITION  Priestia filamentosa strain JURBA-X PF_3_scaffold14, whole genome
            shotgun sequence.
ACCESSION   NZ_JAGKQT010000001
VERSION     NZ_JAGKQT010000001.1
KEYWORDS    WGS; RefSeq.
SOURCE      Priestia filamentosa
  ORGANISM  Priestia filamentosa
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Priestia.
REFERENCE   1  (bases 1 to 92059)
  AUTHORS   Murthy,S., Govardhana,M., Sharma,G. and Belur Satyan,K.
  TITLE     Whole Genome Sequencing of Drought-tolerant Plant-Growth Promoting
            and Florescent Bacillus filamentosus JURBA-X
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 92059)
  AUTHORS   Murthy,S., Govardhana,M., Sharma,G. and Belur Satyan,K.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-MAR-2021) Institute of Bioinformatics and Applied
            Biotechnology (IBAB), Jain University, Electronic City Phase I,
            Bengaluru, Karnataka 560100, India
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: nextflow-tychus v. 0.23.0
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 600.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_018971125.1-RS_2024_08_29
            Annotation Date                   :: 08/29/2024 03:01:25
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,686
            CDSs (total)                      :: 4,602
            Genes (coding)                    :: 4,566
            CDSs (with protein)               :: 4,566
            Genes (RNA)                       :: 84
            rRNAs                             :: 7, 10, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 8 (5S, 16S)
            tRNAs                             :: 62
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 36
            CDSs (without protein)            :: 36
            Pseudo Genes (ambiguous residues) :: 0 of 36
            Pseudo Genes (frameshifted)       :: 14 of 36
            Pseudo Genes (incomplete)         :: 23 of 36
            Pseudo Genes (internal stop)      :: 10 of 36
            Pseudo Genes (multiple problems)  :: 11 of 36
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 22:40:31
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 46147
            Orig. end                         :: 69693
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JAGKQT010000001.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..23546
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="azole-containing-RiPP"
                     /region_number="1"
                     /rules="((YcaO or TIGR03604) and (((thio_amide and (PF06968
                     or PF04055 or PF07366)) or Lant_dehydr_C or Lant_dehydr_N
                     or (PF06968 or PF04055 or PF07366)) or (goadsporin_like or
                     PF00881 or TIGR03605)) or TIGR03882 or TIGR03603 or
                     thiostrepton or TIGR03602)"
                     /tool="antismash"
     cand_cluster    1..23546
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="((YcaO or TIGR03604) and (((thio_amide
                     and (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /kind="single"
                     /product="azole-containing-RiPP"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..23546
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:13546](+)"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..13546
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="1"
     misc_feature    complement(252..267)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 20.33"
                     /tool="antismash"
     gene            377..766
                     /gene="rpsK"
                     /locus_tag="J2M30_RS00295"
     CDS             377..766
                     /GO_component="GO:0005840 - ribosome [Evidence IEA]"
                     /GO_function="GO:0003735 - structural constituent of
                     ribosome [Evidence IEA]"
                     /GO_process="GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /gene="rpsK"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016998822.1"
                     /locus_tag="J2M30_RS00295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="30S ribosomal protein S11"
                     /protein_id="WP_019394046.1"
                     /transl_table=11
                     /translation="MARKTNTRKRRVKKNIESGIAHIRSTFNNTIVTITDMQGNAISWS
                     SAGALGFRGSRKSTPFAAQMAAETAAKTGMENGLKTLEVTVKGPGAGREAAIRALQAAG
                     LEVTAIKDVTPVPHNGCRPPKRRRV"
     gene            941..1885
                     /locus_tag="J2M30_RS00300"
     CDS             941..1885
                     /EC_number="2.7.7.6"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA]"
                     /GO_function="GO:0046983 - protein dimerization activity
                     [Evidence IEA]"
                     /GO_process="GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003178382.1"
                     /locus_tag="J2M30_RS00300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="WP_019394045.1"
                     /transl_table=11
                     /translation="MIEIEKPKIETVEISDDGKFGKFVVEPLERGYGTTLGNSLRRILL
                     SSLPGAAVTSIQIDGVLHEFSTIPGVVEDVTNIILNVKKLALKIYSDEEKTLEIDVQGK
                     GVVTAADIQGDSDVEILNPDLHIATLETDAQFRMRLTAQTGRGYDAAVENKHEDQPIGV
                     IPIDSIYTPVTRVSYYVENTRVGQMTNFDKLTLDVWTDGSIEPEKAVALGAKILTEHLN
                     IFVGLTDEAQKAEIMVEKEEDQKEKVLEMTIEELDLSVRSYNCLKRAGINTVQELANKT
                     EEDMMKVRNLGRKSLEEVKAKLEELGLGLRKDD"
     gene            1922..2284
                     /gene="rplQ"
                     /locus_tag="J2M30_RS00305"
     CDS             1922..2284
                     /GO_component="GO:0005840 - ribosome [Evidence IEA]"
                     /GO_function="GO:0003735 - structural constituent of
                     ribosome [Evidence IEA]"
                     /GO_process="GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /gene="rplQ"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388025.1"
                     /locus_tag="J2M30_RS00305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="50S ribosomal protein L17"
                     /protein_id="WP_040056346.1"
                     /transl_table=11
                     /translation="MGYQKLGRTSAQRKALLRDLATDLIISERIETTEPKAKELKSVVE
                     KLITLGKRGDLHARRQAAAYIRHEVANEETGQDAVQKLFSDVATRYADRQGGYTRIMKL
                     GPRRGDGAPMAIIELV"
     misc_feature    2348..2364
                     /note="TFBS match to NtrC, Nitrogen regulatory protein C,
                     confidence: medium, score: 21.87"
                     /tool="antismash"
     gene            2460..3299
                     /locus_tag="J2M30_RS00310"
     CDS             2460..3299
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019394043.1"
                     /locus_tag="J2M30_RS00310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="WP_019394043.1"
                     /transl_table=11
                     /translation="MSNSVIEVKDLYFRYEEDGPYVLNNLSLNVYKGEWLAIAGHNGSG
                     KSTLAKILNGLILPEQGSVKVADLMLTEDSVWDVRRHIGMVFQNPDNQFVGSTVEDDVA
                     FGLENNGFPYEEMRKRVGEAIEVVGMKGFEQYEPHRLSGGQKQRIGIAGVVAMAPDVIL
                     LDEATSMLDPKGRSEVLETIRLLKNQRNLTIISITHDLNEVAKADRAIVLNKGELFATG
                     TPAEIFELGSKLTEIGLDFPFASQISHVLRDKGISLEHIHLTTDNLVEELWRLYSKM"
     gene            3275..4147
                     /locus_tag="J2M30_RS00315"
     CDS             3275..4147
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019394042.1"
                     /locus_tag="J2M30_RS00315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="WP_019394042.1"
                     /transl_table=11
                     /translation="MEIIFKNVEHRYQLKTPFERLALEDVSLSIPSGQFVSLIGHTGSG
                     KSTVIQHLNALLKPTKGSIQIGDRTIESGKKEKHLKEIRKRVGVVFQFPEHQLFDETVE
                     KDICFGPMNFGVSEEEAKKRANELATIVGLPKEVLQKSPFDLSGGQMRRVAIAGILAME
                     PQVLVLDEPTAGLDPRGRNEIMNLISSLNKEQGLTIVFVTHSMEDAAQYADRIIVMDKG
                     KVSMSGTPKEIFKQHEKLKEIGLDIPEPLQFILDLEQRLGVSLSHEAITFKKAVEEVTK
                     LFGGQAHDE"
     gene            4137..4934
                     /locus_tag="J2M30_RS00320"
     CDS             4137..4934
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019394041.1"
                     /locus_tag="J2M30_RS00320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="WP_019394041.1"
                     /transl_table=11
                     /translation="MMNNMIIGQYVPGDSFIHRMDPRAKLIIVFLYVAVIFLANNIVSY
                     SIIGLFAILSVLVSRVPIYFIIKGLKPILFIIIFTFLLHIFMTREGEVIANIGFLKIYE
                     GGVIQGIYISLRFLFLILLTTLLTLTTTPIEVTDGMETLLHPLKKVRFPVHELALMMSI
                     SLRFIPTLMDETDKILKAQTARGVDFSSGPLKDRLKAVVPLLIPLFISAFKRAEELATA
                     MEARGYQGGEGRTKYRQLSWGSIDTMALVIFVIVAAALFIVRV"
     gene            4947..5690
                     /gene="truA"
                     /locus_tag="J2M30_RS00325"
     CDS             4947..5690
                     /EC_number="5.4.99.12"
                     /GO_function="GO:0003723 - RNA binding [Evidence IEA]"
                     /GO_function="GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA]"
                     /GO_process="GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /GO_process="GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /gene="truA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000439681.1"
                     /locus_tag="J2M30_RS00325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="WP_040056345.1"
                     /transl_table=11
                     /translation="MRRIQCTVAYDGTLFSGYQIQPNARTVQEEIEKALTRLHGGKEVK
                     IHASGRTDASVHAKGQVFHFDTTSTISVSQLKRGANALLPEDIVVVDTKETAEDFHARF
                     SVKKKEYRYKVLCSKSRDVFLRHYMHHVPYELDRKVMKEAIKGIIGTHDFTSFCSAKTE
                     IEDKVRTIYEAEIIEEGDVLTFRFVGNGFLYNMVRILVGTLLDLGNGKSFTKDISGMLE
                     AKNRTLTGKTAPGHGLYLWKVYYDN"
     gene            5834..6271
                     /gene="rplM"
                     /locus_tag="J2M30_RS00330"
     CDS             5834..6271
                     /GO_component="GO:0005840 - ribosome [Evidence IEA]"
                     /GO_function="GO:0003735 - structural constituent of
                     ribosome [Evidence IEA]"
                     /GO_process="GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /gene="rplM"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388030.2"
                     /locus_tag="J2M30_RS00330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="50S ribosomal protein L13"
                     /protein_id="WP_019394039.1"
                     /transl_table=11
                     /translation="MRTTYMAKASEVERKWLVIDAEGKTLGRLASEVASILRGKHKPTY
                     TPHVDTGDHVIILNAAKIELTGKKLTDKIYYRHSQHPGGLKSRTALEMRTNYSEKMLEL
                     AIRGMLPKGSLGRQMFKKLHVFAGDTHPHEAQKPEVYELRG"
     gene            6292..6684
                     /gene="rpsI"
                     /locus_tag="J2M30_RS00335"
     CDS             6292..6684
                     /GO_component="GO:0005840 - ribosome [Evidence IEA]"
                     /GO_function="GO:0003735 - structural constituent of
                     ribosome [Evidence IEA]"
                     /GO_process="GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /gene="rpsI"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002009728.1"
                     /locus_tag="J2M30_RS00335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="30S ribosomal protein S9"
                     /protein_id="WP_019394038.1"
                     /transl_table=11
                     /translation="MAQVQYYGTGRRKSSVARVRLVPGNGNIVVNGREIENYLSSAALR
                     EVVKQPLAATETLGNYDVLVNVNGGGFTGQAGAIRHGIARALLQADPEYRATLKPEGLL
                     TRDARMKERKKYGLKGARRAPQFSKR"
     misc_feature    7041..7054
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.16"
                     /tool="antismash"
     gene            7118..7330
                     /locus_tag="J2M30_RS00340"
     CDS             7118..7330
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="J2M30_RS00340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_046218146.1"
                     /transl_table=11
                     /translation="MEESNFTEKDISTVETSILSSVEASTVIIISVTWFDTRLQSIQWF
                     GEMIMLIFITGLSIGENKVADKGKC"
     gene            7648..7890
                     /locus_tag="J2M30_RS00345"
     CDS             7648..7890
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:TIGR03601.1"
                     /locus_tag="J2M30_RS00345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="heterocycloanthracin/sonorensin family
                     bacteriocin"
                     /protein_id="WP_308281797.1"
                     /transl_table=11
                     /translation="MLNVDDFQATQAVPWDQNQYYTDQDRQFVGVGVGFGRCFSCFNCF
                     NCFSCFRCFNCFNCYNCARCSRCSRCGGGRCGGGS"
     aSDomain        8049..8345
                     /aSDomain="Heterocycloanthracin_C_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing C protein in a
                     heterocycloanthracin LAP cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_J2M30_RS00350_Heterocycloanthracin_C_
                     RRE.1"
                     /evalue="8.10E-52"
                     /identifier="RREFam011.1"
                     /label="J2M30_RS00350"
                     /locus_tag="J2M30_RS00350"
                     /protein_end="99"
                     /protein_start="0"
                     /score="164.2"
                     /tool="antismash"
                     /translation="MANLNPSMRLKVKRDTFYLPEPNRGVYFRNNLSSFRIEGSGIDQW
                     VEKLLPMFNGEYTLGNLTNGLPGPYRDRIYEIAEVLYTNGYVRDLSQDLPHQLS"
     gene            8049..10004
                     /locus_tag="J2M30_RS00350"
     CDS             8049..10004
                     /GO_process="GO:0030152 - bacteriocin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR03693"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Heterocycloanthracin_C_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thiopeptide_F_RRE"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019394033.1"
                     /locus_tag="J2M30_RS00350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="putative thiazole-containing bacteriocin
                     maturation protein"
                     /protein_id="WP_085118984.1"
                     /sec_met_domain="TIGR03693 (E-value: 2e-232, bitscore:
                     765.5, seeds: 2, tool: rule-based-clusters)"
                     /sec_met_domain="Heterocycloanthracin_C_RRE (E-value:
                     2.8e-51, bitscore: 164.2, seeds: 5, tool:
                     rule-based-clusters)"
                     /sec_met_domain="Thiopeptide_F_RRE (E-value: 3e-15,
                     bitscore: 48.7, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MANLNPSMRLKVKRDTFYLPEPNRGVYFRNNLSSFRIEGSGIDQW
                     VEKLLPMFNGEYTLGNLTNGLPGPYRDRIYEIAEVLYTNGYVRDLSQDLPHQLSDYHLK
                     KHASQIEFVDNLVGSGAARFQVFRQGKVLAVGSGPILNSLVSSLIESGLTKIQVLITDE
                     VPTNRQRLKELVEHARKIDPEVDLKEVPQKKEDWREIVQPFDSILYVSQEGKLEKLRHL
                     HAICREEKKIFLPAICFQQIGLAGPLVHPDSEVCWETAWRRLHHSVLSKNEQSPAFSVT
                     PGSLLANVIVFELFKEVTGVMELEQKNRFFLLDLDTLEGDWHSFLPHPLVTRSISAEWV
                     EDVGSRLQVVLEKVDSSKSLLYFNQLTSEESGIFHIWGEEDLKQLPLAQCRVQAVDPLS
                     EGPAELMRDTICSGLTHEEARREAGLTGIETYASRMVNLIVNTLPLNKNVDGSLVGLEE
                     IVGIGAGESFVEGVGRGLQKCLAEELSKQQLNQKYSVSRVQLNFIEDERSRFYLEALTT
                     IQGAPIIGIGKEVYGFPVVWVGTKDGWYGSADLNITMALQKTLQQALIKVQNKSDSSNE
                     LACEVTSVLLEEKMPVSLSIPACEERIQTDILQGAMEILKRNGKRVSVFELRLEPVFKE
                     QLNGVFGVLLREEESQ"
     aSDomain        8070..8312
                     /aSDomain="Thiopeptide_F_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing F protein in a thiopeptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_J2M30_RS00350_Thiopeptide_F_RRE.1"
                     /evalue="8.70E-16"
                     /identifier="RREFam004.1"
                     /label="J2M30_RS00350"
                     /locus_tag="J2M30_RS00350"
                     /protein_end="88"
                     /protein_start="7"
                     /score="48.7"
                     /tool="antismash"
                     /translation="MRLKVKRDTFYLPEPNRGVYFRNNLSSFRIEGSGIDQWVEKLLPM
                     FNGEYTLGNLTNGLPGPYRDRIYEIAEVLYTNGYVR"
     gene            10001..11947
                     /locus_tag="J2M30_RS00355"
     CDS             10001..11947
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: TIGR03604"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: TIGR03882"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: YcaO"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019394032.1"
                     /locus_tag="J2M30_RS00355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="TOMM precursor leader peptide-binding protein"
                     /protein_id="WP_216700535.1"
                     /sec_met_domain="TIGR03882 (E-value: 1.1e-47, bitscore:
                     154.8, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="YcaO (E-value: 1.7e-77, bitscore: 253.9,
                     seeds: 127, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR03604 (E-value: 2.2e-128, bitscore:
                     420.8, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSFVLVVGEGMLADRVSEELSVYHLVIRKSNFEEGVPRNTDLVL
                     FLDDEWKPSVHQKAEEVLRKTGTPWLRGFVSFGEGVVGPLVRPGAAGCSQCADMRRLMG
                     GRDRTEMWEVQQRLAATGGRGSDPWASSPGLLQMAYLIGVEVQNLLQGDQAYSEGKIYI
                     IDLKTMKSSWHSFLPNPLCPVCGQLPDDSQTLARISLQPSPKIDSGIFRCRQLDEMKKM
                     IVKDYLDNRTGLLNSKMYDLVTPFADASVNLPMFAGDEGTAGRTHSYAESVLTAILEGL
                     ERHCGLEPRGKRTVIHDSFRNLENQALNPLKVGIHAKEQYAQPGFPFKSFDPDRSINWV
                     WGYSLLEERPILVPELLAYYSVGCGSQGFVYETSNGCALGGSLEEAIFYGIMEVVERDS
                     FLMTWYAKLNLPRLDPFTADDQELELMVERMRVVAGYDLYLYNSTMEHGIPSIWAIAKN
                     KKEKGLNLICAAGAHLDPVRAVKSAVHELAGMMLNLDEKFEANQEEYERMLHDSSLVRQ
                     MDDHGMLYGLPQAEERLSFLLDDNGPMQSFKEEFKWKSNHTDLTDDLQDILQVFRQLNL
                     DVVIVDQTTPETIRNGLYCVKVLIPGMLPMTFGHHLTRLTGLERIFRVPMELGYTNKPL
                     TPGQLNPHPHPFP"
     gene            11969..13546
                     /locus_tag="J2M30_RS00360"
     CDS             11969..13546
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: PF00881"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003252868.1"
                     /locus_tag="J2M30_RS00360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SagB family peptide dehydrogenase"
                     /protein_id="WP_040056342.1"
                     /sec_met_domain="PF00881 (E-value: 2e-09, bitscore: 30.4,
                     seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSLEEFLHNLHFDIDKANQPNWEADWEDAPLAYKLYRGLPVVPLS
                     TEVPLTLTGGEPPARLDLNRVGHFLWYVFGFTQLSQSVFPMDSPEQDSYPLQSYRRFAP
                     SGGALYPNELYVYLKVEGLPDGVYYYDVAHHSLVLLREGNFDSYLAKALGNRCDISSCF
                     GTVFVSTMFWKNFFKYNNFAYRLQGLDAGVLIGQLMEVAKRFGFASGVYFQFLDTAINH
                     LLGLSEQKESVYSVIPLSVEVTIWSTNGRNLCENVISKELRQELPAIQPEYLERSLNVK
                     EYPMITAMNAASKLDSTWSFRVIGERGAAERMDSAVALPHIEPLSYDLAEACRNRFSPD
                     MDFVLGRVSQQQLATLLLEATGSFSYRNDLDEAYRSNDSRVTIYSCLYNVEGITNGAYY
                     YDSTEHLLREICPGDYRLHLQTGMSLDNVNLLQVPLCLHVVGDKEFYKTELGYRGYRIQ
                     QMEAGMLVQRLLLAAQALGMGGHPLLGFDANLSDELYKIDQQGKTSLIQIPIGPYRPRP
                     WLRGSLHS"
     misc_feature    13682..13694
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 20.68"
                     /tool="antismash"
     gene            14056..14403
                     /locus_tag="J2M30_RS00365"
     CDS             14056..14403
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="J2M30_RS00365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_197064160.1"
                     /transl_table=11
                     /translation="MSKIIEDEHYYNNCYKVIDDILEFERVYMVDEYQFNKETYEMLGK
                     IYKSLPCYLRDYVDFPHWYGCEEKGDQYFISVSFEMSGLQFWGNVPITQFSQWEKALHE
                     GIEDFPFKYQS"
     gene            14434..15483
                     /locus_tag="J2M30_RS00370"
     CDS             14434..15483
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0010181 - FMN binding [Evidence IEA]"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1251: luciferase
                     family protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019394029.1"
                     /locus_tag="J2M30_RS00370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="WP_216700536.1"
                     /transl_table=11
                     /translation="MEIGISTFVETTPDVKTGEVISHAQRIREVVEEIVLADQVGLDVF
                     GVGEHHREDYASSSPAVILAAAASQTNNIRLTSAVTVLSSADPVRVFQDFATLDGISNG
                     RAEIMAGRGSFIESFPLFGYDLRDYEELFDEKLDLLLKLQTSEKITWSGKHRPAIENLG
                     VYPRPVQKPLPIWIGSGGNQESVIRAGLLGLPLVLAIIGGSPLHFAPLVELYKKAAEHA
                     GHDSSKLKVASHSHGFIADDTETATDNFFPPTQYAMNKLGKERGWGPYNRSSFDAARSF
                     EGALYVGDADTVAEKIIHLRKEVGIERFMLHVPVGTMPHEDVMRAIELLGTKVAPKVKA
                     EVARWESIQ"
     gene            complement(15515..18055)
                     /locus_tag="J2M30_RS00375"
     CDS             complement(15515..18055)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019394028.1"
                     /locus_tag="J2M30_RS00375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="NACHT domain-containing protein"
                     /protein_id="WP_046218151.1"
                     /transl_table=11
                     /translation="MAELERHEEFAALLSKGVKSLKHHPNYKIKRNRSESASLGQSYLD
                     KIAYQIGVSSNTIKSWMGQMGLKYIPGRIDDGKLFGILWTIIKEEYMNKEWFTNVLATT
                     SIPTITPPIPIWVASCFRKAKILRNDSSFGPPNEGEINEVISKLFDSHPSHPTSEIKEE
                     PLMHNLPTRGSGQFIGRHQELEVIRQWIHSPSPVCLIAGWAGMGKTTIALEAAYLCIEQ
                     INRNQEWPVFKHIIWINGDWKGLSFNDFLDTIAYQLGRAEQIDKSIAEKRLVVRNVLAI
                     YSQQQPLLLIVDSIDTAESEIYEFVMGLPQGVKVILTARENLNQKYKAGFLEINTIQLK
                     GFEEGEASDFFSYEISRHLQTYPSSTKKTKIEQLLNIPLNVQKELILATAGNPKALSLS
                     IAYILDNNIPVEQLIQKIRNAGYSLVELFDFLFGSTWDKCNEDTQRLWQVLCFFHSPPD
                     EKSWATAAGLDSRKFHYAVERLRTHALVQQNYIGDKPHYLAHQTVVTYGKQHLDADEDF
                     EKNSRKRWSQYYIQYLDTHLKREQPQFIYWSYLLGRDLEELKQEWPNILKALEWASKHA
                     EKELVMNLILRLSHFLSRVNLPLRIQYGLEAADYAHQMNDKISEALIRIDIIGWALMEV
                     NKLEEAYSQIEEGLLILKATDEIHQEAHDLKIWGLALKAKFFLKTDRIKEAKNILKKIC
                     SVPVIPVIKHRVLLMQGDFCLLTKNYKEAIHFYELANEKSMLYGGEKTIEAYFNLGLAY
                     MHCDFYEKAEKMFNNLLYNQNKPNQIELIYCYYGKAQILARKRKYKEAYDLNEKVINLI
                     HSWEPIINIRQEVEEFHKSMNENLLKNTNIRDGI"
     misc_feature    complement(18100..18118)
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: medium, score: 27.7"
                     /tool="antismash"
     gene            18297..19358
                     /locus_tag="J2M30_RS00380"
     CDS             18297..19358
                     /NRPS_PKS="Domain: PKS_ER (18-269). E-value: 8.8e-15.
                     Score: 46.5. Matches aSDomain:
                     nrpspksdomains_J2M30_RS00380_PKS_ER.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1040: alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388496.1"
                     /locus_tag="J2M30_RS00380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="NAD(P)-dependent alcohol dehydrogenase"
                     /protein_id="WP_120045901.1"
                     /sec_met_domain="ADH_N (E-value: 8.2e-37, bitscore: 118.1,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 5.5e-34, bitscore:
                     109.7, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTNNVPTTMKAAVMHSIRDIRIETLPVPQLKDDEVLVKVMAVGIC
                     GSDLHYYTDGRIGHYKVEKPIILGHECAGEVAAIGANVNRVKVGDRVAVEPGVTCGTCE
                     ACKEGRYNLCPDVEFLATPPVDGAFVQYIKMRQDFVFQIPDTLSYEEAALIEPFSVGIH
                     AAARTKLQAGEIVAIMGMGPVGLMAVVAAKAVGASQIIVTDLEPLRLEAAKEMGATHTI
                     NVAEQDPMDEISKITRGKGVDVAWETAGNPAALQSALSSLRRGGRLAIVGLPAQNEIPL
                     NIPFIADNEVDIYGIFRYANTYPKGINFLSSGVVDAKKLVTDRYRLEDTMEAMERALNH
                     KNECLKIVVYPNQ"
     aSDomain        18351..19103
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_J2M30_RS00380_PKS_ER.1"
                     /evalue="8.80E-15"
                     /label="J2M30_RS00380_PKS_ER.1"
                     /locus_tag="J2M30_RS00380"
                     /protein_end="269"
                     /protein_start="18"
                     /score="46.5"
                     /tool="antismash"
                     /translation="DIRIETLPVPQLKDDEVLVKVMAVGICGSDLHYYTDGRIGHYKVE
                     KPIILGHECAGEVAAIGANVNRVKVGDRVAVEPGVTCGTCEACKEGRYNLCPDVEFLAT
                     PPVDGAFVQYIKMRQDFVFQIPDTLSYEEAALIEPFSVGIHAAARTKLQAGEIVAIMGM
                     GPVGLMAVVAAKAVGASQIIVTDLEPLRLEAAKEMGATHTINVAEQDPMDEISKITRGK
                     GVDVAWETAGNPAALQSALSSLRRGGRLA"
     gene            19447..20847
                     /locus_tag="J2M30_RS00385"
     CDS             19447..20847
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0015486 -
                     glycoside-pentoside-hexuronide:cation symporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0006812 - monoatomic cation transport
                     [Evidence IEA]"
                     /GO_process="GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019394026.1"
                     /locus_tag="J2M30_RS00385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="glycoside-pentoside-hexuronide (GPH):cation
                     symporter"
                     /protein_id="WP_216700537.1"
                     /transl_table=11
                     /translation="MIERERTAIEENSNKKLSYSNSRLSWIERFGYGLGDMSYNIIFQF
                     VNAYLLFYYTDIGGISPGVIATLFIVVRVLDAIFDPIMGVILDKTNTRWGKARPYLLWV
                     SIPFGLFTVLCFTTPNFGANGNIAYAYITYILLGMTFSMQTIPVNSLTGRITNNIQERT
                     ILTTTRMILVYIGILLSISCATPLANALGGENQAVGFQLTAIIYAAVSIVLNLMSFSTV
                     RERVAPKKSKKHSIKKMLSVLFKNKPLLILASSFLAFAIGFNIKLSTMVYYFTYNVDRK
                     DLVFMGTLLFFGAALISNLFIPYFSDRWGRKKVMIVTAALSLFTYAGLQFTSYSSLTLI
                     FILLFASGFFTTPLNTLAWGMVADCVDYAEWKTGVRADGVVISSMSFTNKLGVALAGSF
                     AALYLGRNGYVANTEQTINSLDAIKNMNALVPGVFILLSIIIICFYPLNEKKYKKMIEE
                     LNQRPSYK"
     gene            20903..21886
                     /locus_tag="J2M30_RS00390"
     CDS             20903..21886
                     /EC_number="2.7.1.-"
                     /GO_function="GO:0016301 - kinase activity [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1276: PfkB domain protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019394025.1"
                     /locus_tag="J2M30_RS00390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="carbohydrate kinase"
                     /protein_id="WP_040056337.1"
                     /transl_table=11
                     /translation="MQNTVKKKASVVCIGELLIDFFCTDIDVDLTRGKQFLKNAGGAPA
                     NVSAAIAKLGGDALFSGKVGDDSFGYFLKQTLENLNVDTSMLVMDKEAITTLAFVSLTN
                     DGERDFMFHRGADALLTIDDINQDKIDSAKILHFGSATALLENPFQETYLTLMKKANED
                     GIFTSFDPNYRMDLWRGRIDEFVDLAKVAISSSDFVKVSEEELHLITDTIDNLAGINVL
                     HGLGAKIVAVTLGKKGTLLSNGKRAELIKSVPIVAVDSTGAGDAFVGATLYKLAGKENL
                     EDVHMNFEQLYEIISFANKVGAHVCTKIGAIAALPNIEELHELSIS"
     gene            22097..22867
                     /locus_tag="J2M30_RS00395"
     CDS             22097..22867
                     /EC_number="1.1.1.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0070403 - NAD+ binding [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KR (10-129). E-value: 2.3e-11.
                     Score: 35.9. Matches aSDomain:
                     nrpspksdomains_J2M30_RS00395_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010331469.1"
                     /locus_tag="J2M30_RS00395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_046218155.1"
                     /sec_met_domain="adh_short (E-value: 2.9e-35, bitscore:
                     114.5, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short_C2 (E-value: 4.3e-36, bitscore:
                     117.7, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKANFDLTGKVAFVTGAGRGIGRTIAEGLASAGADVILLARTEGE
                     IGEAADAIAEKTGRKTLPIVCDVTNSSSIQEAVDFALQQFHKIDILINNAGTSVRKTSF
                     ELLEEEWDTVIDVNFKSVFLLSKVIGKHMVEQKWGRIINIASVASSLTLSSGTPYGPSK
                     AGVVQLTRQLANEWAKDGITVNAISPWFFKTSLNEEALDNKDFRIIIENRTPMKRLGNL
                     EELITPVIMFCSDGAGYITGQNLFVDGGVTHYGF"
     aSDomain        22127..22483
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_J2M30_RS00395_PKS_KR.1"
                     /evalue="2.30E-11"
                     /label="J2M30_RS00395_PKS_KR.1"
                     /locus_tag="J2M30_RS00395"
                     /protein_end="129"
                     /protein_start="10"
                     /score="35.9"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="VAFVTGAGRGIGRTIAEGLASAGADVILLARTEGEIGEAADAIAE
                     KTGRKTLPIVCDVTNSSSIQEAVDFALQQFHKIDILINNAGTSVRKTSFELLEEEWDTV
                     IDVNFKSVFLLSKVI"
     CDS_motif       22136..22219
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_J2M30_RS00395_0001"
                     /evalue="6.50E-05"
                     /label="PKSI-KR_m1"
                     /locus_tag="J2M30_RS00395"
                     /protein_end="41"
                     /protein_start="13"
                     /score="15.6"
                     /tool="antismash"
                     /translation="VTGAGRGIGRTIAEGLASAGADVILLAR"
     misc_feature    complement(23077..23092)
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 23.25"
                     /tool="antismash"
     misc_feature    complement(23386..23400)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 22.33"
                     /tool="antismash"
ORIGIN
        1 gcaggtgtag atatccctcg tgataagcgc gtagttatct caatgactta cgttttcgga
       61 atcggtaaag taacagctca aaaaatctta gctgaagctg gcgtttctga agatactcgc
      121 gttcgcgatc taacagaaga tgaattaaat aaaattcgtg aaattgttga cggatataaa
      181 gtagaaggag atcttcgtcg tgaagtttct ctaaacatca aacgtctaat cgaaattggt
      241 tcttaccgtg gtcttcgcca ccgtcgtagc ttaccagttc gtggtcaaca tactaaaaac
      301 aatgctcgta cacgtaaagg tccacgtcgt acagtagcta acaaaaagaa ataataagta
      361 agggaggtta tccaacatgg ctcgtaaaac aaacactcgt aaacgtcgtg tgaaaaagaa
      421 tattgagtca ggtatcgctc acattcgttc aactttcaac aatacgattg taacgatcac
      481 tgatatgcaa ggtaatgcga tttcttggtc tagtgctggt gcacttggat tccgtggatc
      541 tcgtaaatct actccattcg ctgcacaaat ggctgctgaa acagctgcta aaacaggtat
      601 ggaaaatggt ttaaaaacat tagaggttac agttaaaggc cctggtgctg gtcgtgaagc
      661 agctatccgt gctcttcaag cagcaggact tgaagtaaca gcaattaaag atgttacacc
      721 agtacctcat aatggatgcc gtccgccaaa acgtcgtcgt gtataattaa ttcatctgta
      781 tatatttcat tttatcgtct ataatgggat atgatacaga tttttttccg gtcaaatgtt
      841 gtgcacattc gggaactgtc taagagggaa tttcggttag atcatttagg atctaaatga
      901 tctaactggg gtttcgacgt tttgaaggag ggtttaataa atgatagaga ttgaaaagcc
      961 aaaaatcgaa acggtagaaa tcagcgatga tggaaagttc ggtaagttcg tcgtcgaacc
     1021 acttgagcgt ggatatggta ctactttggg taactcctta cgtcgtatcc tattatcctc
     1081 tctccctggt gctgctgtaa catctattca aatcgatggt gttttacatg agttctcaac
     1141 aattcctgga gttgttgaag acgtaacaaa catcatttta aatgtgaaga agcttgcatt
     1201 aaaaatctac tctgatgaag agaagacgtt agaaattgat gttcaaggca aaggtgttgt
     1261 aactgctgct gacattcaag gagatagtga tgttgagatc ttaaatccag atcttcatat
     1321 tgcaacactt gaaacagatg cacagttccg catgcgtcta acagctcaaa caggtcgtgg
     1381 ttatgatgct gcggttgaga acaagcatga agatcaacca attggtgtaa ttccaattga
     1441 ttcaatctac acgcctgtta cgcgcgtctc ttactatgtt gaaaatacac gcgttggtca
     1501 aatgacaaac ttcgataagc ttacgcttga tgtttggact gacggtagta ttgagcctga
     1561 aaaagctgta gcactaggtg ctaaaatcct aacagagcat ttaaacatct ttgttggatt
     1621 aacagatgag gcacaaaaag cagagattat ggttgaaaaa gaagaagatc aaaaagagaa
     1681 agttcttgaa atgacgattg aagaacttga cctttctgta cgttcttaca actgcttaaa
     1741 acgtgctggc atcaacacag tacaagagct tgcgaataaa acagaagaag atatgatgaa
     1801 agtacgtaac ttaggacgta aatctcttga agaagtgaaa gctaaacttg aagagcttgg
     1861 tcttggacta cgtaaagacg attgatagat agcgaattag taacgaagga gggaaatact
     1921 catgggatat caaaaattag gtcgtacaag tgcacaacgt aaggcacttc ttcgcgattt
     1981 agcaactgac ttaatcatca gtgagcgcat tgaaacaaca gaaccaaaag caaaagaact
     2041 taagtctgtt gtagaaaaac taatcactct tggtaaacgt ggagatctac atgctcgccg
     2101 tcaagctgca gcatacatcc gccacgaagt agcaaacgaa gagactggtc aagacgctgt
     2161 tcaaaaactt ttcagcgacg tggctactcg ttatgctgac cgtcaaggtg gctacactcg
     2221 tattatgaaa cttggacctc gtcgtggtga cggtgctcca atggctatca tcgagttagt
     2281 ttaatatatg aagttcttag ggcgtatgga ttctcttctt ttttaaagaa agtgtctgac
     2341 gcccatttga acaatatagg tgctacaagg gcgtgacagt tattctcaac tgctcaatgc
     2401 ccttttttta tatgttgaaa cgaattagcc tagaggagca tagtagaggg gggctgtata
     2461 tgtcaaactc agtcatagaa gtgaaagact tgtattttcg gtatgaagaa gatggacctt
     2521 atgtgctaaa caacttatct cttaatgttt ataagggaga atggcttgca attgcaggac
     2581 ataatggctc agggaaatca acgcttgcta aaattttaaa cggtctcatt ctacctgaac
     2641 aaggttctgt gaaagtagca gatcttatgc ttacagaaga ttctgtatgg gatgtacgtc
     2701 gccatattgg aatggtattt caaaatcctg ataatcaatt tgtaggttca acggttgaag
     2761 acgacgttgc ttttgggtta gagaataatg gctttccgta tgaagagatg agaaaaagag
     2821 taggggaagc aattgaagtt gttggaatga aagggttcga gcagtatgag ccacatcgtc
     2881 tatctggtgg gcagaagcag cgtattggta ttgctggtgt tgtcgcaatg gcacctgatg
     2941 ttatcctttt agatgaagca acatcaatgc ttgatccaaa aggacgtagt gaagttctcg
     3001 aaaccattcg tttgttaaaa aatcaacgca atctaacgat tatctccatt acccatgacc
     3061 tcaatgaagt agcgaaagct gatagagcaa ttgtcctcaa taaaggagaa ctttttgcaa
     3121 ctgggacacc tgcagagatt tttgaacttg gcagcaaatt gactgagatt ggccttgatt
     3181 ttccatttgc tagtcaaatt agtcatgttc tgagggacaa aggaatttct ttagaacata
     3241 ttcatttaac aacggacaac ttagtggagg aactatggag attatattca aaaatgtaga
     3301 acatcgttat cagcttaaaa caccttttga acgattagca ttagaagatg tatcgctatc
     3361 cattccctct ggtcagttcg tatcgttaat cggtcataca ggatctggta agtcaacagt
     3421 tatccagcat ttgaatgccc ttttaaaacc aactaaaggg agtatccaaa taggagatcg
     3481 tacaattgaa agtggtaaga aagaaaagca tttaaaagaa attcgtaaac gcgttggcgt
     3541 tgtctttcag tttcctgaac atcagctttt tgatgagact gttgaaaaag atatttgttt
     3601 tggtccgatg aactttgggg tttcagaaga ggaagcgaaa aaaagggcaa atgagcttgc
     3661 tacaatagtt ggtttgccaa aggaagttct gcagaaatca ccgtttgatt taagcggtgg
     3721 acagatgcgc cgtgtggcaa ttgcaggaat tttagcaatg gaaccgcaag tgcttgttct
     3781 tgatgagcca acagcaggac ttgatccaag aggacgtaat gagattatga atttgatctc
     3841 ctctttaaat aaagaacaag gattaacgat tgtatttgta acgcacagta tggaagatgc
     3901 agcacaatat gcagatcgca ttattgtaat ggataaaggg aaagtttcaa tgagtggaac
     3961 accaaaggaa atctttaagc aacatgaaaa gcttaaagag attggactag atatcccaga
     4021 gcctctgcag ttcatattgg atctagaaca gcgtttgggc gtttccctta gtcatgaggc
     4081 tattacattt aaaaaggccg tagaagaggt cacaaagctt tttggaggac aagctcatga
     4141 tgaataatat gattattggt cagtatgttc caggagattc ttttattcat cgtatggacc
     4201 ctcgtgcaaa gcttattatt gtttttttat atgtagctgt tatttttctt gcgaataata
     4261 ttgtaagcta cagcattatt ggtttgtttg ctattttatc agtacttgta agtcgagttc
     4321 caatttattt cattattaaa ggactaaagc caatattgtt tattattata ttcacctttc
     4381 tccttcatat ttttatgacg agagaaggag aagtaatcgc gaacattggt tttctaaaga
     4441 tctatgaagg cggagttatt caagggattt atatttcgct tcggttctta ttcttaattt
     4501 tacttacaac cctgttaact cttacaacga caccaattga ggtaacagat ggcatggaga
     4561 cacttttaca tccattaaaa aaagtccgtt tccctgttca tgaattagca cttatgatgt
     4621 ctatttcgct tcgtttcatt cccactttga tggatgaaac agacaaaatc ttgaaggctc
     4681 aaacagcacg gggagtagac ttttcgagcg ggcctcttaa agatcgtcta aaggccgttg
     4741 tgccactctt aattccgctt tttattagcg cttttaaacg tgcagaagag ctagcaacag
     4801 ctatggaagc aagaggatat caaggtggag aaggacggac aaagtatcgt cagcttagct
     4861 gggggtctat tgatactatg gctcttgtca tatttgttat tgttgctgct gctctattta
     4921 tcgtaagagt ctaggagatg tgagagatgc gaagaattca atgtactgta gcatatgacg
     4981 gaacactttt ttcaggttat caaattcagc ctaatgcccg tactgtgcaa gaagagattg
     5041 aaaaagccct tacccgtctc catggaggta aggaagtgaa aatccatgcc tcaggacgta
     5101 cagatgcctc tgtccatgct aaagggcaag tgtttcactt tgatactaca agtactatca
     5161 gtgtaagcca gcttaagcga ggagctaatg cactcttgcc agaagatatt gtggtagttg
     5221 atacaaagga aacggcagaa gattttcatg ctcgttttag cgtgaaaaag aaggaatacc
     5281 gttacaaagt gctttgcagc aaaagtcgtg atgtgttctt aaggcattac atgcatcatg
     5341 ttccatacga gttagatcgt aaggtgatga aggaagctat aaagggcata attggtacac
     5401 atgatttcac gagtttttgt tcagcgaaga cggagataga agataaagtg agaacaatct
     5461 atgaagcgga aattattgaa gaaggagacg tgcttacatt tagatttgtg ggaaacggat
     5521 ttctttataa tatggttcga attttagtgg gaacacttct tgatcttggt aacggaaaaa
     5581 gttttacaaa agatatttca gggatgctag aggcgaaaaa tcgcactcta acaggcaaaa
     5641 ctgcacctgg acatgggcta tacttgtgga aagtttacta tgacaactaa acctggtgta
     5701 acatcctctt gacattggga atacaacagg ctaatataac atatgtatgt aattttaaac
     5761 ccacgattag ccccggaaat taatcgtgtt taaaataaaa cgttcgaaag ttgaaattct
     5821 aggagggtaa aacatgcgta caacttatat ggcgaaagca agtgaagtag agcgcaaatg
     5881 gcttgtaatt gacgcagaag gtaaaacttt aggtcgtctt gctagcgaag ttgcttctat
     5941 tctacgcggg aaacataaac caacttacac accacacgtt gatactggtg atcatgtaat
     6001 cattcttaat gcagcaaaaa tcgaattaac aggtaaaaaa ttgactgaca agatttacta
     6061 ccgtcacagc caacatccag gcggacttaa atctcgcacg gctcttgaaa tgcgtactaa
     6121 ctattcagag aaaatgcttg aactagcaat ccgtggaatg cttccaaaag gtagcttagg
     6181 tcgtcaaatg tttaagaaat tacatgtgtt tgcaggagac actcatccac atgaagcaca
     6241 aaaaccagaa gtttatgaac ttcgcggata atacgtaagg agggaattat attggcacag
     6301 gtacaatatt acggaacagg tcgtcgtaaa agctctgttg ctcgcgtacg tctagtacca
     6361 ggtaacggaa acatcgttgt taacggtcgt gaaatcgaga actatctttc atctgcagca
     6421 ctaagagaag ttgtaaaaca acctcttgct gcaacagaaa ctcttgggaa ctatgatgta
     6481 ttagtaaacg taaacggtgg aggattcact ggtcaagctg gagcaatccg ccacggtatc
     6541 gctcgtgcac tattacaagc agacccagaa tatcgtgcaa cactaaaacc tgaaggtcta
     6601 ttaactcgtg acgctcgtat gaaagaacgt aaaaaatacg gtcttaaagg cgctcgtcgt
     6661 gcacctcagt tctcaaaacg ttaatatttc ttatatatca acgttttaca accctttctc
     6721 ggattttcgg gaaagggttt tttatttatt tatttagata taaaataaat acctaattta
     6781 agaaattagg gtttttgctg ttgttatctt ttgatttgat aaaaagagaa tataattcct
     6841 caccatgttc aataagttct ccaacgttgg aattagttgc ttctagtatt ttatctaatg
     6901 tattaaattg aatccccatt attttcacca tttgcaataa ggctcaaagc attctgagag
     6961 attcctgtaa tctcatgcaa ttcagtcata gtcatacctt ttgtttcaac agttgtttca
     7021 gataataata cttttaatgt attttttaat agaaatttta cgtaataaaa caaggaaaaa
     7081 aacgtacttc acagctacaa aggaactttt atttaacatg gaagagtcaa actttactga
     7141 gaaggatatt agcacggtgg aaacgagtat tttatcaagt gtagaggctt caaccgtcat
     7201 tatcatttca gtcacttggt tcgatacgag gctccaaagc atccaatggt ttggtgaaat
     7261 gattatgctt atatttatca cggggctgtc gattggagaa aataaagtcg ctgataaagg
     7321 taagtgttga gtatataaat gtccaaaaat aatacactag ttctgatgat tcagccgccg
     7381 attcaggcgg ttttttgttt ttataatcgt cctgtttgcg ttttgaacgt ttttttccgg
     7441 ttccattaaa ttaggctttt gtatcagtaa caatacccat ctattgtaca tagtttgttg
     7501 aagagtattc gaaatatgta atgtattcat ttagtataca gttttttttc gatttaactc
     7561 gactgttttc atttcaagtt tctggcaccc tttgttaatt tatttgagga ggaaaagaaa
     7621 atgaatgatt ttcaaagtga acttcaaatg ttgaatgttg atgatttcca agcgactcag
     7681 gcagtccctt gggatcaaaa tcaatactat actgatcagg atcgacaatt cgttggtgtg
     7741 ggggttggtt ttggccgatg ctttagttgc tttaactgtt ttaactgctt tagttgcttc
     7801 cgttgtttta actgctttaa ctgctataac tgcgctcgtt gctcacgttg ctctagatgc
     7861 ggcggtggcc gttgtggtgg cggcagctaa gccggtaata gtttattttt ctatgttgag
     7921 aaggtcccct gcattgttgc aggggtcttt ctctataaga taagacataa cggacaaatt
     7981 gctatacata cgatggtagt ggtaatgata ttgaacattt atggttacaa ggggtaagga
     8041 ggagagagat ggcaaatttg aacccttcta tgcgtctgaa agtaaaaagg gacacgtttt
     8101 atctccctga accaaacaga ggtgtgtatt ttcgaaacaa cttaagttca ttccgtattg
     8161 aaggaagtgg gatcgatcag tgggttgaaa agttgttacc gatgttcaat ggggagtata
     8221 ctttaggaaa tttgactaat ggattgcctg gcccataccg ggaccgcata tatgaaattg
     8281 cagaagtgct gtatacgaat gggtatgttc gagatttaag ccaggacctt ccgcatcaat
     8341 tgtcggatta tcatcttaaa aagcatgcat cacaaattga atttgtggac aatttagttg
     8401 gttctggggc ggcccgtttt caagtttttc gtcagggcaa agtgcttgca gttggctctg
     8461 gtcctatttt aaattcattg gtttcctcgt tgattgaatc gggtttgact aagatccaag
     8521 tactaattac agacgaggtt ccgaccaata gacagaggtt aaaagaactc gtggaacatg
     8581 cacgaaaaat agatccggag gttgacttaa aggaggttcc acaaaagaag gaggattggc
     8641 gagagatagt gcagcccttt gattcaattt tgtatgtgag tcaagagggg aagctagaga
     8701 aacttagaca tcttcatgca atttgcaggg aagagaagaa aatatttctc cccgctatat
     8761 gctttcaaca gataggttta gcaggtccat tagtacatcc agattccgag gtgtgttggg
     8821 aaacagcatg gcgccgttta catcattctg tcttatctaa aaatgagcaa tcccctgcct
     8881 tctctgtcac cccgggatcg ttgttagcta atgtgatcgt gtttgaattg tttaaagagg
     8941 ttacaggtgt catggaattg gaacagaaga ataggttttt tcttctggat ttggatacat
     9001 tggagggaga ctggcattca tttttgcctc atcccctggt aacaaggagt atatctgcag
     9061 aatgggttga agatgtcgga agccggctcc aagtagtctt agagaaagtt gattcaagta
     9121 aatcacttct ttatttcaac cagttgacat cagaggaatc gggaattttc catatttggg
     9181 gggaggagga tttaaagcag cttccattag ctcagtgccg cgttcaggca gtcgacccgt
     9241 tgtcggaggg accagctgag ttgatgcgag acactatctg ttcaggtcta actcatgagg
     9301 aggcacgaag agaagcggga ctaactggga ttgaaacgta tgcgtcgcga atggttaatt
     9361 tgatcgttaa tactctgccg ctaaataaaa atgttgatgg aagtttagta ggactggagg
     9421 aaattgtcgg gattggagcg ggtgaatcgt ttgtggaagg tgttggccgt gggttgcaaa
     9481 agtgtttggc agaggagctt agcaagcaac aacttaatca gaagtattct gtttctcgag
     9541 tacagttaaa ttttatagaa gatgagagat cccggttcta tttagaagca ctgactacga
     9601 tacaaggagc accaattatc ggaataggga aggaagtgta cggctttcct gtagtgtggg
     9661 taggtacaaa agatggatgg tatggtagtg cagatttaaa tataacaatg gcgttacaga
     9721 agacattaca gcaggcactt atcaaagtac aaaacaaatc ggattcttct aatgaactag
     9781 cctgtgaggt aacgtccgta cttttggaag agaaaatgcc ggttagtctt agcattcctg
     9841 cgtgtgaaga gaggatacaa acggacatcc tacagggagc tatggaaata ttgaaacgga
     9901 atggaaaaag ggtctcggta tttgaattaa ggctcgaacc tgtttttaaa gagcaactaa
     9961 acggagtgtt tggtgttttg ctgcgagagg aggaatcaca gtgagttcct tcgtgttggt
    10021 tgtcggagaa gggatgctgg cggaccgtgt aagtgaagaa ctgtcggtat atcatctagt
    10081 tattcgtaaa tccaattttg aggaaggagt tccaagaaat actgatttgg tccttttttt
    10141 ggatgacgag tggaaaccct ctgttcatca aaaggcggaa gaagtgttac gaaagacggg
    10201 tactccctgg cttagaggct tcgtttcatt tggcgaaggt gtagttggcc cgcttgtacg
    10261 accaggtgca gcaggttgct ctcaatgtgc ggacatgaga cgtctcatgg gaggacgtga
    10321 ccgcacagag atgtgggagg tgcaacagag gctggctgcg actggaggaa ggggaagtga
    10381 cccgtgggct tcaagtcccg gacttttgca aatggcttac ctgattggag ttgaggtaca
    10441 gaatttatta caaggcgatc aagcttattc ggaaggtaag atatatataa ttgacttgaa
    10501 aacaatgaag agctcatggc attcttttct gcccaacccg ttgtgtccag tctgtggtca
    10561 attacccgac gattcacaga cattagcccg aatttcactg cagccaagtc caaaaataga
    10621 ttccggaatt ttccgatgcc gtcagttgga tgagatgaaa aaaatgattg tcaaagacta
    10681 tttggataat cgtaccggcc ttttgaatag taaaatgtat gacctagtga ctccatttgc
    10741 tgatgcgagt gtcaatctcc ctatgtttgc tggggacgag ggaacagctg gcaggactca
    10801 ttcatacgca gaaagtgtgt tgacagccat tttagaggga ttggagcggc actgtggttt
    10861 agaaccacgt ggcaaacgga cagtaatcca tgatagtttt cgtaacctgg aaaatcaagc
    10921 gctcaatcca ttgaaggtag gtatacacgc aaaagaacaa tatgcgcaac ctggttttcc
    10981 atttaaatcg tttgatcctg atcgttctat taattgggta tggggttatt cgttgctaga
    11041 agagcgtccc atcctagttc cagagctcct tgcctattac agtgttggat gtgggtcaca
    11101 aggctttgtc tatgaaactt ccaatggatg tgcgttagga ggaagtttag aggaggccat
    11161 tttctacggg attatggaag tggtcgagcg tgattcattc ctgatgactt ggtatgcgaa
    11221 gctgaacctt ccgcgactgg atccttttac agctgacgac caggagttgg aattaatggt
    11281 cgaaaggatg cgagtggtcg ctgggtatga tttgtatttg tataactcca cgatggaaca
    11341 cgggattcca agtatttggg cgattgctaa aaacaaaaag gaaaagggat tgaatcttat
    11401 ctgtgcggcc ggagctcatc tggatccggt aagggcggtg aaaagcgcag ttcacgagct
    11461 tgctggcatg atgctgaacc ttgatgaaaa atttgaggcg aaccaggaag agtatgaaag
    11521 aatgctgcat gattcttctc tggttcggca gatggatgac cacggcatgc tgtatggttt
    11581 gccgcaagca gaagagcgct taagtttttt gcttgacgac aatggcccaa tgcaatcttt
    11641 taaagaggag tttaagtgga agtcgaatca tacggatctt accgatgatt tgcaagacat
    11701 ccttcaggtg ttccgtcagt taaaccttga tgtagttata gtagaccaga cgacaccgga
    11761 aacgatacga aacggtttgt attgcgtaaa agtactgatt ccgggaatgc tgccgatgac
    11821 atttgggcat caccttaccc gcctgacagg gcttgagagg atatttcgag tccctatgga
    11881 gcttgggtat acgaataaac cattgacacc aggacagctc aatccacatc cgcatccgtt
    11941 tccataagca gtgattagga ggtataggat gagtctggaa gaatttctgc acaatctgca
    12001 ttttgatatt gataaggcaa atcagccgaa ctgggaagcg gattgggagg atgcaccgct
    12061 tgcatataaa ctctaccgtg gattaccggt tgttccattg tccacggaag taccgctgac
    12121 gcttactgga ggagaacctc ccgcaagact ggaccttaat agagttggtc attttctctg
    12181 gtatgtattc ggttttactc aattgagcca atcagtcttt ccaatggatt ccccagagca
    12241 agattcctac cctttgcagt cgtatcgacg gtttgctcct tctggtgggg cgttataccc
    12301 taacgaattg tacgtgtatt tgaaggtaga gggactccct gatggagtct actattatga
    12361 tgtagcacac catagcctgg tattgttgcg ggaagggaat ttcgattcct atttagccaa
    12421 ggcactagga aatcggtgtg acatctcctc gtgttttggt actgtctttg tgtcaaccat
    12481 gttctggaaa aattttttta aatacaacaa ttttgcatac cgactccaag gattggatgc
    12541 tggtgtgctg attggacagt taatggaggt agcgaaacgg tttggctttg cctcaggggt
    12601 gtactttcaa tttcttgata ccgcaatcaa tcatctgctt ggactatccg aacagaagga
    12661 gagcgtatat agtgtaatcc cattatcggt ggaagtcacc atctggtcta ctaacggaag
    12721 gaatctatgc gaaaatgtta tatcgaagga attgagacaa gagctgccag cgattcaacc
    12781 agaatatctc gagcgatcac ttaatgtcaa agagtatccg atgataactg cgatgaacgc
    12841 agcttctaag ctggattcca catggtcatt tcgagtgatc ggggagaggg gagctgcgga
    12901 acgtatggat tccgcggtgg cattgcctca tatagagccc ttgtcatatg atttggctga
    12961 ggcctgcaga aatcggtttt ctcccgacat ggatttcgtt ttggggaggg tgagtcaaca
    13021 acaattggct acccttcttc tagaagcaac gggttctttt tcataccgga atgatttgga
    13081 tgaagcatat aggagtaacg actctcgtgt aacaatttat agctgtttat ataatgttga
    13141 aggtattaca aatggggcgt actattatga cagcacagaa cacttgttaa gagaaatatg
    13201 cccaggagac tatcgactcc atttacagac tggaatgtct ctggataatg tgaatttgct
    13261 ccaggtacca ctttgcctgc atgtggttgg tgacaaggaa ttctataaaa cagaactagg
    13321 atacaggggc tatcgaatcc aacagatgga agcaggcatg ctcgtgcaac gattgctttt
    13381 ggctgcgcaa gctctcggga tgggagggca cccgcttctt ggatttgacg cgaatttgag
    13441 tgatgaactc tataaaatag atcaacaagg aaagaccagt ctaatccaaa tccccattgg
    13501 tccctatcgc cctcgtcctt ggctgagggg aagtttgcac agctaattaa ggtatagagc
    13561 aatatgtact tagttatagg ttaagaaaac tacttcctta tatttaatat ataaataaaa
    13621 gaacgtaaaa atacagtctt aaaggcgatc gtcatgcacc tcagttctca aaacgttaat
    13681 tttacgtttt gcaaaaccct ttctcggatc tctgaggaag ggtttttttg tttatttaaa
    13741 taaatttctc ttttttaaca atatatgcaa tggtattaaa aactagccgc tgtttctcta
    13801 actacaagtt atcgtgagta tatttctttt ttattgacac ctaaggcatt attattgaga
    13861 ttatagtgtt aattagaatg cacaaaagta gaaaggcaaa atacatttta cttttattta
    13921 ggacaagtac agaaactata aatactcttt ccaatacata taagctattg ctacttgtaa
    13981 ggtctgtaaa ttcagttgtt ggagcttatg gacaagataa tataaaggct aaataacata
    14041 aggagaagaa cggtgatgag caaaattata gaagatgaac attattacaa taattgctac
    14101 aaagttatag acgatatatt agaatttgaa cgagtatata tggtagatga ataccaattt
    14161 aataaagaga catatgaaat gctagggaag atatataaga gcttgccatg ttatttaaga
    14221 gattacgttg atttccctca ttggtatggt tgcgaagaga aaggggatca atactttatt
    14281 agtgtttcat ttgaaatgtc tggactacag ttctggggga acgtgccgat cacacaattt
    14341 tcgcaatggg aaaaagcctt gcatgaaggg atagaagact ttccttttaa atatcaatca
    14401 taaaggccgt aattctgaag gaggataaga taaatggaga taggaattag tacctttgta
    14461 gaaacaactc cagatgtaaa aacaggagaa gtaattagtc atgcacaacg cattcgagaa
    14521 gtagtagagg aaattgttct ggcagatcaa gttgggttag acgtatttgg ggtaggagag
    14581 catcatcgtg aagactatgc ttcttcttct cctgctgtta tattggcagc agcggcttca
    14641 cagaccaata atattcgctt aacaagtgct gttactgttc tttcctcagc agatcctgtt
    14701 cgcgtttttc aagactttgc aacgcttgat ggcatttcaa atgggcgtgc tgagattatg
    14761 gcaggaagag ggtcttttat tgagtcattt ccgctctttg gttatgattt aagagattat
    14821 gaagaactgt ttgatgaaaa gctagatttg cttttaaagc tacaaacgtc tgagaagatt
    14881 acatggagcg gaaagcatag accagctatt gagaatttag gtgtctaccc aaggcctgtc
    14941 caaaaaccgt taccaatttg gattggaagt ggaggaaacc aagagtctgt tataagggca
    15001 gggcttctcg gacttccact tgtgttggcg attatcgggg gcagcccgct tcattttgct
    15061 ccgcttgtgg agctatacaa aaaagcagca gaacatgcag gtcatgactc atccaaatta
    15121 aaagtggctt cccattctca tgggtttatt gcagatgata cagaaacagc tactgataat
    15181 ttttttcctc ctacacaata tgcgatgaac aagcttggaa aagaacgtgg ctggggacct
    15241 tataaccgct caagcttcga tgcggcccga agctttgaag gagctcttta cgtaggggat
    15301 gcagatacag tagcggagaa gattattcat ctgcgtaagg aggttgggat agaacgcttt
    15361 atgcttcatg ttccggttgg gacaatgcca catgaagatg ttatgagagc cattgagctt
    15421 ctagggacaa aagtggcccc gaaagtgaag gcagaggttg cgcgctggga atcaatccaa
    15481 taaagaatgt ttaatataca aatataaggg atggctagat gccatccctt atatttgtat
    15541 tttttagtaa gttctcattc attgatttat gaaattcttc tacttcctgg cggatattaa
    15601 taattggttc ccatgagtga attaaattaa tgaccttttc atttaaatca tatgcttcct
    15661 tgtactttct ttttcgagca agtatttgag ctttgccata atagcagtag ataagctcaa
    15721 tttgatttgg tttattttga ttataaagaa ggttattgaa cattttttct gccttttcat
    15781 agaaatcgca atgcatatag gctaatccta ggttgaagta tgcttcaatc gttttttcgc
    15841 ctccgtataa catgctcttt tcatttgcta attcataaaa atgaatagct tctttataat
    15901 ttttagtcag taaacaaaaa tctccttgca ttaataaaac acgatgtttg atgacaggta
    15961 taacagggac actacatatc ttctttaata tgttctttgc ttcttttatc cggtccgttt
    16021 ttaaaaaaaa ttttgctttt aaggcaagtc cccaaatctt aagatcgtgc gcttcttgat
    16081 ggatctcatc tgttgctttt aatatgagga gtccttcttc tatttggcta tatgcttctt
    16141 ctaatttatt tacttccata agcgcccatc caataatatc aattcgaatc aaagcctcag
    16201 aaatcttatc attcatttga tgagcgtaat cagcagcctc taatccatac tgaattctta
    16261 gcggtagatt aacgcgactt agaaaatgac tgagacggag tattaaattc attactaatt
    16321 ctttctcagc atgtttactt gcccattcta aggcttttaa aatattgggc cattcttgtt
    16381 taagttcctc taaatcccga ccaagtaagt aactccaata tatgaattgt ggttgttcgc
    16441 gctttaaatg agtatctaaa tattgaatat aatactgact ccaacgcttt cttgagtttt
    16501 tctcaaaatc ctcatcagca tctaaatgtt gtttaccata agttactact gtttgatgtg
    16561 ctaaataatg tggtttatcc ccaatataat tctgttgtac aagagcatga gttcgcaacc
    16621 tctcaacagc ataatgaaat tttcgagagt ccaatccagc ggctgtagcc caacttttct
    16681 cgtcaggggg gctatgaaag aaacagagca cttgccaaag ccgttgagta tcttcattac
    16741 acttgtccca tgtactgcca aataaaaagt caaatagctc aacaagagag taaccggcat
    16801 ttcttatttt ttggataagc tgttcaacag ggatattatt atctagaata taagcaatgc
    16861 taagtgatag tgctttagga ttgccggcag tagctaaaat aagctccttt tgaacattta
    16921 aaggaatatt taataattgc tctatctttg tttttttggt tgaggaaggg taagtttgga
    16981 gatgtcgact tatttcataa gagaaaaaat ccgatgcttc cccttcctca aaccctttta
    17041 gttgaatcgt atttatttct aaaaagcctg ctttatattt ttgatttaaa ttttcacgag
    17101 cggttaaaat gaccttcact ccttgaggaa ggcccatgac aaattcataa atctcacttt
    17161 cagctgtgtc gatactgtct acaataagaa gtagaggctg ttgttgagaa taaatggcca
    17221 agacattccg gacaacaagg cgtttttctg caatagattt gtcaatttgc tctgcacgtc
    17281 ctagttggta ggcaatcgta tctaagaagt cattaaaact taatcctttc caatcgccat
    17341 taatccaaat aatatgttta aatacaggcc attcctggtt tctgtttatc tgttcaatac
    17401 ataaatatgc ggcttcaagg gctattgtag ttttacccat gcctgcccat ccggcaataa
    17461 gacaaacggg ggaaggggaa tgaatccatt gtctaataac ttctagttcc tggtgacgac
    17521 caataaattg tcctgatcct cgggtaggca agttatgcat taacggttct tcctttatct
    17581 cagacgttgg atgagaggga tgggaatcaa atagtttaga aataacctcg ttgatttctc
    17641 cttcatttgg tggaccaaat gaagaatcat ttctcaatat ctttgccttc ctaaaacaag
    17701 aagctaccca aatcggaatt ggtggtgtaa tagtaggaat tgaagttgtt gctaatacat
    17761 ttgtgaacca ttctttgttc atatactctt ccttaataat agtccacaag attccaaaaa
    17821 gttttccatc atctatccgt ccgggaatat atttcaaacc catttgcccc atccaactct
    17881 taatggtgtt agaagaaaca cctatttgat atgcaatctt atctaaataa gattgaccta
    17941 gagaggcgct ctcacttctg tttcttttta ttttgtaatt agggtgatgc tttaatgact
    18001 taacaccctt tgatagcaag gcggcaaact cctcatgccg ttcaagttca gccatatcgc
    18061 ccactcctgt cttggttata agatgaaaag tacagtgtgg ctgtactttt atacagtgta
    18121 aaaagctact gtacaactag atagatatat acaatgaaat tgtataatac agattccaaa
    18181 atgtatgcac ttacatcata attctaggga gtatgatagt caacttgaga aatgaagagt
    18241 gttatataga aaagggatcc acattcttaa ctcttttatt agaaaggaaa atgatgatga
    18301 ctaacaatgt acctacaaca atgaaagcag cggttatgca tagtataaga gatattcgga
    18361 ttgaaacttt accagtgcca caactaaagg atgatgaggt tttagttaaa gtaatggctg
    18421 ttggaatttg tggttctgat ttacattact atacagatgg acgaattggt cactataaag
    18481 tagaaaaacc aattattctt ggccatgaat gcgcaggaga agtggccgct attggagcta
    18541 atgttaatag ggtgaaagtt ggggatcgtg ttgcagttga acctggtgtt acttgcggga
    18601 catgtgaagc ctgtaaggaa ggaagatata atctttgtcc agatgtagag tttttagcaa
    18661 ctcctcctgt tgatggggca tttgttcaat atataaaaat gagacaggac tttgtttttc
    18721 aaattccaga taccctttca tatgaagaag cagctttaat tgaacctttt tcagtaggaa
    18781 ttcatgcagc agcaagaaca aagcttcaag caggcgagat agtagctatt atgggaatgg
    18841 gaccagttgg tttgatggct gttgtggcag ctaaagcagt tggggcaagt caaattatcg
    18901 taacagactt agaaccatta cgacttgaag cggcaaaaga aatgggagca acacatacaa
    18961 ttaatgttgc agaacaagac cctatggatg agattagcaa gattacacgt ggcaagggcg
    19021 tagacgttgc gtgggaaaca gcgggaaacc cagctgctct tcaatctgct ctttcttcct
    19081 tacgacgtgg tggaagactt gcaattgtag ggctgcctgc tcaaaatgaa attcctctta
    19141 atattccatt tattgcagat aacgaagttg atatttatgg tatctttcgt tatgccaaca
    19201 catatccaaa aggaattaat tttctctctt caggggtagt tgatgctaaa aaattagtta
    19261 ctgatcgata tagactagag gatacgatgg aagctatgga acgagcactc aaccataaaa
    19321 atgaatgttt aaaaattgtt gtgtatccaa atcaataaat agaaaagaga aatagacgtg
    19381 cagattaata tcttttaatc tgcatcacaa cacataacaa tgaaaacgga ttctaggggt
    19441 gtagttatga tagagagaga acgaaccgca atagaagaaa attcgaataa gaagctgtct
    19501 tattcaaatt ctcgcttatc atggatagaa cgatttgggt atggacttgg ggatatgtcc
    19561 tacaatatta tctttcaatt tgtgaatgcg tatctacttt tttattacac agatattggt
    19621 ggaatctcac caggggttat tgcaacatta tttattgttg tgcgtgtact agatgctatc
    19681 tttgatccaa taatgggtgt cattttagat aaaacaaata caagatgggg aaaagcaaga
    19741 ccatatttat tatgggtttc cattcctttt gggttattca ctgtactatg ttttacaaca
    19801 ccgaactttg gagcaaatgg aaacatagcc tatgcttata ttacgtatat cctattaggg
    19861 atgacattta gtatgcaaac aatccctgtt aacagtttaa cagggcgcat cacaaataac
    19921 atccaagaaa gaacaatatt aacaacaacg cgtatgattc ttgtttatat tggaatcctt
    19981 ctgtctatct catgtgcaac gccacttgcg aatgccttag gaggagagaa tcaagccgtt
    20041 ggatttcaat taacagctat catttatgca gcagtaagta ttgttctaaa tcttatgagt
    20101 ttctctacgg tccgcgagag agttgcaccg aaaaaaagta agaaacacag tattaagaaa
    20161 atgttatcag tattatttaa aaataaacca ttacttattt tagcttcgtc ctttttagcc
    20221 tttgcaattg gatttaatat taagttaagt acaatggtgt actactttac gtataatgtt
    20281 gatcgtaaag atttagtatt tatgggaaca ctattatttt tcggagcagc tttaattagt
    20341 aatttattta ttccgtactt ctctgatcga tggggaagaa agaaagttat gatcgtaaca
    20401 gcagcactat cgttgtttac ttatgctgga ttgcagttta catcatattc gtctctcacc
    20461 ttaatcttta ttttactctt tgcttcaggc ttttttacaa cccctctgaa tacacttgct
    20521 tgggggatgg ttgcagactg cgtagattat gcagaatgga aaacaggagt aagagcagat
    20581 ggggtagtaa tctctagtat gagttttaca aataaactag gggttgcctt agctggatcg
    20641 tttgcagcgc tttatttagg aaggaacgga tatgtagcaa atacagaaca aaccattaat
    20701 tctttagatg ctattaaaaa tatgaatgca ttagtgccag gagtatttat cttactgtcc
    20761 attattatta tttgtttcta tcctttaaat gagaagaagt ataaaaagat gatagaagag
    20821 ttaaatcaaa gaccttccta taaataagaa gaaacatatg ttatgccttt ttaaagtcaa
    20881 aaaataaaat gagagtgata aaatgcaaaa caccgtaaag aaaaaagcat cagttgtttg
    20941 tattggagag ctattaattg atttcttttg tacagatatt gatgttgatt taacaagagg
    21001 aaaacagttt ttaaaaaatg ctgggggtgc ccctgctaat gtctctgctg ccattgctaa
    21061 gctaggtgga gatgccttat ttagtggaaa ggtaggggat gactcttttg gctacttttt
    21121 aaaacaaaca ttagagaatc tcaatgtaga tacttcaatg cttgtgatgg acaaggaagc
    21181 aataacaact ctagcatttg tatctttaac aaacgatgga gagcgagatt tcatgttcca
    21241 tagaggagca gatgcgttgc tcacaataga tgatattaat caagataaaa tagatagtgc
    21301 taagattcta cactttggat ctgcaacagc attattagaa aacccttttc aagagacata
    21361 tttaacactt atgaaaaaag ctaatgagga tggaatattc acctcgtttg atccaaatta
    21421 tcgtatggat ttgtggagag ggagaataga tgagtttgta gatcttgcaa aagtagctat
    21481 ttcttcaagt gactttgtta aagtaagcga agaggaatta caccttatta cagacactat
    21541 agataatcta gcaggtatta atgttcttca tggccttggt gctaaaattg ttgccgttac
    21601 tctaggtaaa aaggggacgc ttctatctaa tgggaagagg gcagagctta ttaaaagcgt
    21661 tccaatcgtt gctgttgatt ctacaggagc aggagatgcc tttgttggag caacattata
    21721 taaactagca ggtaaggaaa atcttgaaga tgtccatatg aattttgaac aactgtatga
    21781 aattatttct tttgccaata aagtgggggc tcatgtttgt acgaaaatag gagcaatagc
    21841 tgccttgcca aatattgagg aacttcatga gttgagtata agttagttga tatagacaga
    21901 tacaaagaca aaaggctaag caatgcacta tttccttgct tagttttttt gtctttattt
    21961 tataactggc tcaagtaaaa agaaaaggat aaacgttagc atgaaagaat ttaaagggta
    22021 aatattatgt aagaggtctt taacggagct cataaaggga acataataaa cgcagaatat
    22081 tggagggagt aacacattga aagcaaattt tgacttaaca ggtaaagtcg catttgttac
    22141 aggggcggga agaggaatag gaagaacaat agctgaagga ttagcaagtg ctggagctga
    22201 tgttatcctt ttagcaagaa cggaaggtga gattggggag gctgctgatg ctattgctga
    22261 aaagacagga agaaaaactt taccgattgt gtgcgatgta acgaacagtt cctctatcca
    22321 agaagctgtt gattttgctc ttcagcaatt tcataaaatt gatattttaa ttaataatgc
    22381 tggaacaagc gtgagaaaga cgagcttcga gctgttagaa gaagaatggg acactgtaat
    22441 agatgtgaac tttaaatctg ttttcttgct ctcaaaagtt attggaaagc atatggtgga
    22501 acagaaatgg ggccgaatta ttaatatagc ttctgttgct tcttctttaa cattatcatc
    22561 tggaactcca tatggaccaa gtaaagctgg agttgttcaa ctaacacgtc agttagcaaa
    22621 tgaatgggct aaggacggga taacagtaaa tgcaataagt ccgtggttct ttaaaacgtc
    22681 cttgaatgaa gaagctttag ataataagga ctttagaata ataatagaaa atcgtacccc
    22741 tatgaagaga ttaggaaatc ttgaagaatt gattacacct gttattatgt tttgttcaga
    22801 tggagcaggc tacataacag gacagaattt atttgtagat gggggagtaa cgcattacgg
    22861 cttttgataa taactgagta agaagagtta tttatttacc ataatcgttt taaatgaaga
    22921 atgtatcgca atatgatgat ataagaaatt ctgaattatt gtagagaaaa tgcaccaaat
    22981 cattatgatt tggtgcattt tctaagttat tactattggc attttagaac taaaactggg
    23041 ctttaagtat ggaagtatca ctatcttatt ttgctttttt acaattgaaa attgttaagg
    23101 gaagatgccc taacttgtta ttttttctga agtacggaag aatttttaga ttttctttcc
    23161 gatactttta agaactctta ttcttgatga gctatatcag gaacaatgca tttaaaagga
    23221 ataggtgatg aaaggacaat agatgtatta gcatgaccaa acggaagcag ggaatctata
    23281 agctgactta aatgcttcat acttgaaaca gcagctttca gtaaatagtt aacagaacca
    23341 gttaatcgat ggcattcaat aatattagga ttttctaaaa tccatttctc aaattctgaa
    23401 taggatttta ttcgtaggtc acttagctgg ataaatacga ggatatccct tccaattgca
    23461 gaagtagcca cgcgtgcact aaatccctcg ataatgcctt tttcttgtaa gcgctttaat
    23521 ctttcagaaa tactaggacg acttag
//
