Select genomic region:
Overview
1.1
1.2
2.1
9.1
14.1
14.2
14.3
18.1
19.1

### Identified secondary metabolite regions using strictness 'relaxed'

NZ_JAGKQT010000018.1 (Priestia filamentosa)

Region | Type | From | To | Similarity Confidence | Most similar known cluster
--- | --- | --- | --- | --- | ---
Region 1.1 | T3PKS | 177,308 | 218,396 |
Region 1.2 | terpene | 456,049 | 476,867 |

NZ_JAGKQT010000022.1 (Priestia filamentosa)

Region | Type | From | To | Similarity Confidence | Most similar known cluster
--- | --- | --- | --- | --- | ---
Region 2.1 | terpene | 56,602 | 78,458 |

NZ_JAGKQT010000023.1 (Priestia filamentosa)

Region | Type | From | To | Similarity Confidence | Most similar known cluster
--- | --- | --- | --- | --- | ---
Region 9.1 | betalactone | 458,851 | 483,540 | Low | fengycin | NRPS:Type I

NZ_JAGKQT010000003.1 (Priestia filamentosa)

Region | Type | From | To | Similarity Confidence | Most similar known cluster
--- | --- | --- | --- | --- | ---
Region 14.1 | terpene-precursor | 444,197 | 465,075 |  |
Region 14.2 | lassopeptide | 884,190 | 908,043 | Medium | paeninodin | ribosomal:unmodified
Region 14.3 | NRP-metallophore,NRPS | 926,942 | 978,576 | High | bacillibactin/bacillibactin E/bacillibactin F | NRPS:Type I

NZ_JAGKQT010000001.1 (Priestia filamentosa)

Region | Type | From | To | Similarity Confidence | Most similar known cluster
--- | --- | --- | --- | --- | ---
Region 18.1 | azole-containing-RiPP | 46,148 | 69,693 |

NZ_JAGKQT010000007.1 (Priestia filamentosa)

Region | Type | From | To | Similarity Confidence | Most similar known cluster
--- | --- | --- | --- | --- | ---
Region 19.1 | lanthipeptide-class-ii,cyclic-lactone-autoinducer | 70,661 | 100,236 | Low | locillomycin/locillomycin B/locillomycin C | NRPS:Type I+PKS

Region | Type | From | To | Similarity Confidence | Most similar known cluster
--- | --- | --- | --- | --- | ---
Region 1.1 | T3PKS | 177,308 | 218,396 |
Region 1.2 | terpene | 456,049 | 476,867 |
Region 2.1 | terpene | 56,602 | 78,458 |
Region 9.1 | betalactone | 458,851 | 483,540 | Low | fengycin | NRPS:Type I
Region 14.1 | terpene-precursor | 444,197 | 465,075 |  |
Region 14.2 | lassopeptide | 884,190 | 908,043 | Medium | paeninodin | ribosomal:unmodified
Region 14.3 | NRP-metallophore,NRPS | 926,942 | 978,576 | High | bacillibactin/bacillibactin E/bacillibactin F | NRPS:Type I
Region 18.1 | azole-containing-RiPP | 46,148 | 69,693 |
Region 19.1 | lanthipeptide-class-ii,cyclic-lactone-autoinducer | 70,661 | 100,236 | Low | locillomycin/locillomycin B/locillomycin C | NRPS:Type I+PKS

No secondary metabolite regions were found in these records:
  NZ_JAGKQT010000004.1 (Priestia filamentosa)
  NZ_JAGKQT010000021.1 (Priestia filamentosa)
  NZ_JAGKQT010000010.1 (Priestia filamentosa)
  NZ_JAGKQT010000024.1 (Priestia filamentosa)
  NZ_JAGKQT010000016.1 (Priestia filamentosa)
  NZ_JAGKQT010000006.1 (Priestia filamentosa)
  NZ_JAGKQT010000013.1 (Priestia filamentosa)
  NZ_JAGKQT010000019.1 (Priestia filamentosa)
  NZ_JAGKQT010000017.1 (Priestia filamentosa)
  NZ_JAGKQT010000009.1 (Priestia filamentosa)
  NZ_JAGKQT010000012.1 (Priestia filamentosa)
  NZ_JAGKQT010000008.1 (Priestia filamentosa)
  NZ_JAGKQT010000015.1 (Priestia filamentosa)
  NZ_JAGKQT010000005.1 (Priestia filamentosa)
  NZ_JAGKQT010000002.1 (Priestia filamentosa)
  NZ_JAGKQT010000020.1 (Priestia filamentosa)
  NZ_JAGKQT010000011.1 (Priestia filamentosa)
  NZ_JAGKQT010000014.1 (Priestia filamentosa)

Compact view
NZ_JAGKQT010000018.1 - Region 1 - T3PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 177,308 - 218,396 nt. (total: 41,089 nt) Show pHMM detection rules used
T3PKS: (Chal_sti_synt_C or Chal_sti_synt_N)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
binding site
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
Tailoring
MIBiG comparison
KnownClusterBlast
SubClusterBlast
TFBS Finder
NRPS/PKS domains
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Tailoring functions
Tailoring enzymes detected in this region
Oxidoreductases: dehydrogenase oxidoreductase
J2M30_RS17680: alcohol dehydrogenase

smcogs
  SMCOG1040: alcohol dehydrogenase

J2M30_RS17785: oxidoreductase

smcogs
  SMCOG1079: oxidoreductase

J2M30_RS17850: oxidoreductase

smcogs
  SMCOG1079: oxidoreductase

Transferases: methyltransferase
J2M30_RS17755: isoprenylcysteine carboxyl methyltransferase

smcogs
  SMCOG1150: isoprenylcysteine carboxyl methyltransferase

Hydrolases: dehalogenase hydrolase
J2M30_RS17670: metallo-beta-lactamase family protein

smcogs
  SMCOG1170: metallo-beta-lactamase family protein

J2M30_RS17700: beta-lactamase

smcogs
  SMCOG1053: beta-lactamase

J2M30_RS17715: haloalkane dehalogenase

smcogs
  SMCOG1262: haloalkane dehalogenase

Ligases: synthase
J2M30_RS17760: chalcone and stilbene synthase domain protein

smcogs
  SMCOG1024: chalcone and stilbene synthase domain protein

Similar gene clusters
Shows areas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | T3PKS | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000282.3 |  | 0.55 | PKS | 2-methoxy-5-methyl-6-(13-methyltetradecyl)-1,4-benzoquinone, 2-methoxy-5-methyl-6-(13-methyltetradecyl)phenol | Streptomyces griseus subsp. griseus NBRC 13350
BGC0001831.3 |  | 0.54 | PKS | alkylpyrone-407, alkylpyrone-393 | Myxococcus xanthus DK 1622
BGC0001962.3 |  | 0.49 | PKS | hierridin B, hierridin C | Cyanobium sp. LEGE 06113
BGC0002332.2 |  | 0.48 | PKS | 4-hydroxy-6-pentadecylpyran-2-one, 4-hydroxy-6-(2-oxoheptadecyl)pyran-2-one, Adipostatin A | Candidatus Entotheonella sp.
BGC0001735.5 |  | 0.42 | other (other) | pentostatine, vidarabine | Streptomyces antibioticus
BGC0001521.3 |  | 0.41 | NRPS | auriculamide | Herpetosiphon aurantiacus DSM 785
BGC0002402.2 |  | 0.41 | terpene | Yossoside I, Yossoside II, Yossoside III, Yossoside IV, Yossoside V | Spinacia oleracea
BGC0002407.3 |  | 0.40 | other (other), saccharide | angustmycin A, angustmycin C | Streptomyces angustmyceticus
BGC0001267.3 |  | 0.40 | terpene | elymoclavine, Agroclavine I | Claviceps fusiformis
BGC0002571.2 |  | 0.40 | NRPS | pyoverdine DC3000 | Pseudomonas syringae pv. tomato str. DC3000

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000282.3 |  | 0.55 | PKS | 2-methoxy-5-methyl-6-(13-methyltetradecyl)-1,4-benzoquinone, 2-methoxy-5-methyl-6-(13-methyltetradecyl)phenol | Streptomyces griseus subsp. griseus NBRC 13350
BGC0001831.3 |  | 0.54 | PKS | alkylpyrone-407, alkylpyrone-393 | Myxococcus xanthus DK 1622
BGC0001962.3 |  | 0.49 | PKS | hierridin B, hierridin C | Cyanobium sp. LEGE 06113
BGC0002332.2 |  | 0.48 | PKS | 4-hydroxy-6-pentadecylpyran-2-one, 4-hydroxy-6-(2-oxoheptadecyl)pyran-2-one, Adipostatin A | Candidatus Entotheonella sp.
BGC0001735.5 |  | 0.42 | other (other) | pentostatine, vidarabine | Streptomyces antibioticus
BGC0001521.3 |  | 0.41 | NRPS | auriculamide | Herpetosiphon aurantiacus DSM 785
BGC0002402.2 |  | 0.41 | terpene | Yossoside I, Yossoside II, Yossoside III, Yossoside IV, Yossoside V | Spinacia oleracea
BGC0002407.3 |  | 0.40 | other (other), saccharide | angustmycin A, angustmycin C | Streptomyces angustmyceticus
BGC0001267.3 |  | 0.40 | terpene | elymoclavine, Agroclavine I | Claviceps fusiformis
BGC0002571.2 |  | 0.40 | NRPS | pyoverdine DC3000 | Pseudomonas syringae pv. tomato str. DC3000

Similar known clusters from MIBiG 4.0
Shows clusters from the MIBiG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.
Click on an accession to open that entry in the MIBiG database.

No significant matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.

No significant matches found.

Transcription Factor Binding Sites
Detailed information for Transcription Factor Binding Site hits, including surrounding genes where applicable.
The strand of the match is shown by an arrow underneath the match.
Detailed documentation is available here.
Binding sites found:
PerR
Description: Peroxide regulator
Species: Bacillus & Staphylococcus sp.
Score: 28.14 out of 28.14
Confidence: strong
PerR
Description: Peroxide regulator
Species: Bacillus & Staphylococcus sp.
Score: 25.44 out of 28.14
Confidence: medium
CodY
Description: Regulator of stationary phase and virulence in Gram-positive bacteria
Species: Bacillus, Lactococcus & Streptococcus sp.
Score: 25.04 out of 27.78
Confidence: strong
CodY
Description: Regulator of stationary phase and virulence in Gram-positive bacteria
Species: Bacillus, Lactococcus & Streptococcus sp.
Score: 23.50 out of 27.78
Confidence: medium
MogR
Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 22.90 out of 26.06
Confidence: medium
FuR variant 1
Description: Ferric Uptake Regulator
Species: Bacillus, Pseudomonas, Yersinia sp.
Score: 24.70 out of 29.38
Confidence: medium
FuR variant 1
Description: Ferric Uptake Regulator
Species: Bacillus, Pseudomonas, Yersinia sp.
Score: 25.54 out of 29.38
Confidence: medium
MogR
Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 22.52 out of 26.06
Confidence: medium
MogR
Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 23.52 out of 26.06
Confidence: medium
MogR
Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 23.95 out of 26.06
Confidence: medium
ColR
Description: Phenol-responsive regulator
Species: Pseudomonas putida KT2440
Score: 23.09 out of 30.25
Confidence: medium
ColR
Description: Phenol-responsive regulator
Species: Pseudomonas putida KT2440
Score: 24.96 out of 30.25
Confidence: medium
MogR
Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 23.39 out of 26.06
Confidence: medium
CcpA
Description: Catabolite control protein A
Species: Streptococcus & Clostridium sp.
Score: 19.78 out of 20.97
Confidence: strong
CodY
Description: Regulator of stationary phase and virulence in Gram-positive bacteria
Species: Bacillus, Lactococcus & Streptococcus sp.
Score: 23.30 out of 27.78
Confidence: medium
ZuR variant 1
Description: Zinc-responsive repressor
Species: Streptomyces coelicolor
Score: 22.98 out of 28.19
Confidence: medium
LexA variant 3
Description: Repressor of DNA damage response
Species: Escherichia coli str. K-12 substr. MG1655
Score: 28.89 out of 32.93
Confidence: strong
Additional weak hits (5):
FuR variant 1
Description: Ferric Uptake Regulator
Species: Bacillus, Pseudomonas, Yersinia sp.
Score: 22.50 out of 29.38
Confidence: weak
ColR
Description: Phenol-responsive regulator
Species: Pseudomonas putida KT2440
Score: 22.73 out of 30.25
Confidence: weak
FuR variant 1
Description: Ferric Uptake Regulator
Species: Bacillus, Pseudomonas, Yersinia sp.
Score: 23.36 out of 29.38
Confidence: weak
ZuR variant 2
Description: Zinc-responsive repressor
Species: Pseudomonas protegens Pf-5
Score: 25.17 out of 33.14
Confidence: weak
LexA variant 1
Description: Repressor of DNA damage response
Species: Streptomyces coelicolor
Score: 20.80 out of 29.65
Confidence: weak
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A domain glossary is available here, and an explanation of the visualisation is available here.
Selected features only
Show module domains
TFBS Finder
TFBS definitions
Shows descriptions for Transcription Factor Binding Site models

Regulator | Description
--- | ---
CcpA | Catabolite control protein A
CodY | Regulator of stationary phase and virulence in Gram-positive bacteria
ColR | Phenol-responsive regulator
FuR variant 1 | Ferric Uptake Regulator
LexA variant 3 | Repressor of DNA damage response
MogR | Repressor of flagellar motility genes
PerR | Peroxide regulator
ZuR variant 1 | Zinc-responsive repressor

NZ_JAGKQT010000018.1 - Region 2 - terpene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 456,049 - 476,867 nt. (total: 20,819 nt) Show pHMM detection rules used
terpene: (PT_phytoene_like or phytoene_synt or Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA or TS_Pyr4)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
binding site
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
Tailoring
MIBiG comparison
KnownClusterBlast
SubClusterBlast
Terpene
TFBS Finder
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Tailoring functions
Tailoring enzymes detected in this region
Transferases: aminotransferase
J2M30_RS19145: aminotransferase class V

smcogs
  SMCOG1139: aminotransferase class V

Hydrolases: deacetylase
J2M30_RS19080: acetylornithine deacetylase

smcogs
  SMCOG1247: acetylornithine deacetylase

Similar gene clusters
Shows areas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | terpene | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000923.3 |  | 0.40 | other (other) | paerucumarin | Pseudomonas aeruginosa PAO1
BGC0000846.5 |  | 0.38 | other (other) | tabtoxin | Pseudomonas syringae
BGC0000925.5 |  | 0.37 | other (other) | quinolobactin | Pseudomonas fluorescens
BGC0001221.5 |  | 0.34 | other (phenazine) | marinophenazine A, phenaziterpene A | Streptomyces sp. CNQ-509
BGC0001387.5 |  | 0.31 | other (other) | nucleocidin | Streptomyces calvus
BGC0002443.3 |  | 0.30 | PKS | mycemycin C, mycemycin A, mycemycin B | Streptomyces olivaceus
BGC0001940.3 |  | 0.30 | PKS | pyxidicycline A, pyxidicycline B | Pyxidicoccus fallax
BGC0000197.5 |  | 0.29 | PKS, saccharide | aranciamycin | Streptomyces echinatus
BGC0000193.3 |  | 0.27 | PKS | aclacinomycin | Streptomyces galilaeus
BGC0001540.5 |  | 0.27 | other (other) | CC-1065 | Streptomyces zelensis

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000923.3 |  | 0.40 | other (other) | paerucumarin | Pseudomonas aeruginosa PAO1
BGC0000846.5 |  | 0.38 | other (other) | tabtoxin | Pseudomonas syringae
BGC0000925.5 |  | 0.37 | other (other) | quinolobactin | Pseudomonas fluorescens
BGC0001221.5 |  | 0.34 | other (phenazine) | marinophenazine A, phenaziterpene A | Streptomyces sp. CNQ-509
BGC0001387.5 |  | 0.31 | other (other) | nucleocidin | Streptomyces calvus
BGC0002443.3 |  | 0.30 | PKS | mycemycin C, mycemycin A, mycemycin B | Streptomyces olivaceus
BGC0001940.3 |  | 0.30 | PKS | pyxidicycline A, pyxidicycline B | Pyxidicoccus fallax
BGC0000197.5 |  | 0.29 | PKS, saccharide | aranciamycin | Streptomyces echinatus
BGC0000193.3 |  | 0.27 | PKS | aclacinomycin | Streptomyces galilaeus
BGC0001540.5 |  | 0.27 | other (other) | CC-1065 | Streptomyces zelensis

Similar known clusters from MIBiG 4.0
Shows clusters from the MIBiG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.
Click on an accession to open that entry in the MIBiG database.

No significant matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.

No significant matches found.

Detailed terpene predictions
Detailed information for terpene domains. Shows possible products of a terpene cluster and lists the subtype and expected reactions for each terpene-related domain.
Product predictions:

Class | Subclass | Product name | Chain length | Initial cyclisations | Functional groups
--- | --- | --- | --- | --- | ---
triterpene | C30 carotenoid | diapophytoene | C30 | acyclic | none
triterpene |  | squalene | C30 | acyclic | none
triterpene |  | PSPP | C30 | acyclic | PP
tetraterpene | C40 carotenoid | phytoene | C40 | acyclic | none
triterpene |  | hydroxysqualene | C30 | acyclic | OH

Genes with terpene domains:
J2M30_RS19120: PT_phytoene_like
Domain 1 (14 - 254): Prenyltransferase; Phytoene synthase like
Subtype: unknown

Reactions:
  FPP → diapophytoene
  FPP → squalene
  FPP → PSPP
  GGPP → phytoene
  PSPP → hydroxysqualene

Transcription Factor Binding Sites
Detailed information for Transcription Factor Binding Site hits, including surrounding genes where applicable.
The strand of the match is shown by an arrow underneath the match.
Detailed documentation is available here.
Binding sites found:
CodY
Description: Regulator of stationary phase and virulence in Gram-positive bacteria
Species: Bacillus, Lactococcus & Streptococcus sp.
Score: 22.70 out of 27.78
Confidence: medium
MogR
Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 23.28 out of 26.06
Confidence: medium
MogR
Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 23.52 out of 26.06
Confidence: medium
RutR
Description: Regulator of the pyrimidine and purine metabolism
Species: Escherichia coli str. K-12 substr. MG1655
Score: 21.27 out of 26.85
Confidence: medium
AbrC3
Description: Antibiotic production activator
Species: Streptomyces coelicolor
Score: 17.05 out of 18.16
Confidence: strong
CcpA
Description: Catabolite control protein A
Species: Streptococcus & Clostridium sp.
Score: 19.78 out of 20.97
Confidence: strong
CodY
Description: Regulator of stationary phase and virulence in Gram-positive bacteria
Species: Bacillus, Lactococcus & Streptococcus sp.
Score: 25.15 out of 27.78
Confidence: strong
ToxT
Description: Regulator of MSHA biosynthesis
Species: Vibrio cholerae O395
Score: 18.57 out of 18.57
Confidence: strong
ToxT
Description: Regulator of MSHA biosynthesis
Species: Vibrio cholerae O395
Score: 18.57 out of 18.57
Confidence: strong
CodY
Description: Regulator of stationary phase and virulence in Gram-positive bacteria
Species: Bacillus, Lactococcus & Streptococcus sp.
Score: 25.45 out of 27.78
Confidence: strong
Additional weak hits (1):
PsrA
Description: Oleic acid responsive regulator
Species: Pseudomonas sp.
Score: 20.14 out of 25.88
Confidence: weak
Terpene
TFBS Finder
Glossary
Glossary showing acronyms and their full names.

Acronym | Full name
--- | ---
FPP | Farnesyl diphosphate
GGPP | Geranylgeranyl diphosphate
PP | Diphosphate
PSPP | Presqualene diphosphate

TFBS definitions
Shows descriptions for Transcription Factor Binding Site models

Regulator | Description
--- | ---
AbrC3 | Antibiotic production activator
CcpA | Catabolite control protein A
CodY | Regulator of stationary phase and virulence in Gram-positive bacteria
MogR | Repressor of flagellar motility genes
RutR | Regulator of the pyrimidine and purine metabolism
ToxT | Regulator of MSHA biosynthesis

NZ_JAGKQT010000022.1 - Region 1 - terpene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 56,602 - 78,458 nt. (total: 21,857 nt) Show pHMM detection rules used
terpene: (PT_phytoene_like or phytoene_synt or Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA or TS_Pyr4)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
binding site
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
Tailoring
MIBiG comparison
KnownClusterBlast
SubClusterBlast
Terpene
TFBS Finder
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Tailoring functions
Tailoring enzymes detected in this region
Hydrolases: peptidase
J2M30_RS20050: gamma-glutamyltranspeptidase

smcogs
  SMCOG1274: gamma-glutamyltranspeptidase

Similar gene clusters
Shows areas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | terpene | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001535.3 |  | 0.43 | other (other) | branched-chain fatty acids | Streptomyces filamentosus
BGC0000670.4 |  | 0.35 | terpene | thalianol, thaliandiol, thalianin | Arabidopsis thaliana
BGC0001736.3 |  | 0.31 | NRPS | pepteridine A, pepteridine B | Photorhabdus laumondii subsp. laumondii TTO1
BGC0000663.5 |  | 0.30 | terpene | hopene | Streptomyces coelicolor A3(2)
BGC0000249.5 |  | 0.28 | PKS | nogalamycin | Streptomyces nogalater
BGC0002359.3 |  | 0.25 | NRPS | dudomycin A | Streptomyces albus subsp. chlorinus
BGC0002789.2 |  | 0.25 | PKS | pentamycin, filipin | Streptomyces lavendulae strain YAKB-15
BGC0001394.5 |  | 0.24 | NRPS, PKS | phenalamide A2 | Myxococcus stipitatus DSM 14675
BGC0001567.4 |  | 0.24 | NRPS | cysteoamide | Streptomyces lincolnensis
BGC0001737.3 |  | 0.24 | NRPS, PKS | phenalamide | Corallococcus coralloides

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001535.3 |  | 0.43 | other (other) | branched-chain fatty acids | Streptomyces filamentosus
BGC0000670.4 |  | 0.35 | terpene | thalianol, thaliandiol, thalianin | Arabidopsis thaliana
BGC0001736.3 |  | 0.31 | NRPS | pepteridine A, pepteridine B | Photorhabdus laumondii subsp. laumondii TTO1
BGC0000663.5 |  | 0.30 | terpene | hopene | Streptomyces coelicolor A3(2)
BGC0000249.5 |  | 0.28 | PKS | nogalamycin | Streptomyces nogalater
BGC0002359.3 |  | 0.25 | NRPS | dudomycin A | Streptomyces albus subsp. chlorinus
BGC0002789.2 |  | 0.25 | PKS | pentamycin, filipin | Streptomyces lavendulae strain YAKB-15
BGC0001394.5 |  | 0.24 | NRPS, PKS | phenalamide A2 | Myxococcus stipitatus DSM 14675
BGC0001567.4 |  | 0.24 | NRPS | cysteoamide | Streptomyces lincolnensis
BGC0001737.3 |  | 0.24 | NRPS, PKS | phenalamide | Corallococcus coralloides

Similar known clusters from MIBiG 4.0
Shows clusters from the MIBiG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.
Click on an accession to open that entry in the MIBiG database.

No significant matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.

No significant matches found.

Detailed terpene predictions
Detailed information for terpene domains. Shows possible products of a terpene cluster and lists the subtype and expected reactions for each terpene-related domain.
Product predictions:

Class | Subclass | Product name | Chain length | Initial cyclisations | Functional groups
--- | --- | --- | --- | --- | ---
triterpene | hopanoid |  | C30 | hopanoid skeleton | unknown
triterpene | polypodane |  | C30 | polypodane skeleton | unknown

Genes with terpene domains:
J2M30_RS20030: T2TS
Domain 1 (4 - 617): Type 2 terpene synthase
Subtype: Squalene substrate

Reactions:
  squalene → hopanoid
  squalene → polypodane

Transcription Factor Binding Sites
Detailed information for Transcription Factor Binding Site hits, including surrounding genes where applicable.
The strand of the match is shown by an arrow underneath the match.
Detailed documentation is available here.
Binding sites found:
IolR
Description: Regulator of the inositol catabolism
Species: Caulobacter crescentus CB15
Score: 19.45 out of 23.79
Confidence: medium
CodY
Description: Regulator of stationary phase and virulence in Gram-positive bacteria
Species: Bacillus, Lactococcus & Streptococcus sp.
Score: 22.12 out of 27.78
Confidence: medium
CRP
Description: Cyclic AMP receptor protein
Species: Escherichia coli str. K-12 substr. MG1655
Score: 17.40 out of 19.26
Confidence: medium
MogR
Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 22.53 out of 26.06
Confidence: medium
Additional weak hits (7):
ClgR
Description: Caseinolytic protease gene regulator
Species: Corynebacterium glutamicum ATCC 13032
Score: 20.67 out of 30.22
Confidence: weak
LuxO
Description: Repressor of luminescence
Species: Vibrio campbellii ATCC BAA-1116
Score: 21.78 out of 26.12
Confidence: weak
CopR
Description: Copper-responsive regulator
Species: Lactococcus lactis subsp. lactis Il1403
Score: 23.64 out of 30.97
Confidence: weak
NtrC
Description: Nitrogen regulatory protein C
Species: Pseudomonas putida KT2440
Score: 20.57 out of 29.72
Confidence: weak
SypG
Description: Regulator of biofilm formation and host colonization
Species: Vibrio fischeri ES114
Score: 22.26 out of 29.25
Confidence: weak
DosR
Description: Hypoxia stress response regulator
Species: Mycobacterium tuberculosis H37Rv
Score: 20.48 out of 29.51
Confidence: weak
ColR
Description: Phenol-responsive regulator
Species: Pseudomonas putida KT2440
Score: 22.52 out of 30.25
Confidence: weak
Terpene
TFBS Finder
Glossary
Glossary showing acronyms and their full names.
No acronyms to display
TFBS definitions
Shows descriptions for Transcription Factor Binding Site models

Regulator | Description
--- | ---
CRP | Cyclic AMP receptor protein
CodY | Regulator of stationary phase and virulence in Gram-positive bacteria
IolR | Regulator of the inositol catabolism
MogR | Repressor of flagellar motility genes

NZ_JAGKQT010000023.1 - Region 1 - betalactone
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 458,851 - 483,540 nt. (total: 24,690 nt) Show pHMM detection rules used
betalactone: (HMGL-like and AMP-binding)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
binding site
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
Tailoring
MIBiG comparison
KnownClusterBlast
SubClusterBlast
TFBS Finder
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Tailoring functions
Tailoring enzymes detected in this region
Oxidoreductases: dehydrogenase
J2M30_RS22650: acyl-CoA dehydrogenase

smcogs
  SMCOG1006: acyl-CoA dehydrogenase

Transferases: carboxylase transferase
J2M30_RS22620: acetyl-CoA carboxylase, carboxyl transferase,

smcogs
  SMCOG1059: acetyl-CoA carboxylase, carboxyl transferase,

J2M30_RS22640: acetyl-CoA carboxylase biotin carboxylase

smcogs
  SMCOG1090: acetyl-CoA carboxylase biotin carboxylase

Lyases: hydratase
J2M30_RS22625: enoyl-CoA hydratase

smcogs
  SMCOG1023: enoyl-CoA hydratase

Ligases: ligase synthase
J2M30_RS22630: 2-isopropylmalate synthase

smcogs
  SMCOG1271: 2-isopropylmalate synthase

J2M30_RS22645: AMP-dependent synthetase and ligase

smcogs
  SMCOG1002: AMP-dependent synthetase and ligase

Similar gene clusters
Shows areas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | betalactone | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001166.5 |  | 0.55 | NRPS | HC-toxin | Alternaria jesenskae
BGC0002284.3 |  | 0.51 | other (other) | corynecin III, corynecin I, corynecin II | Rhodococcus sp. H-CA8f
BGC0000706.3 |  | 0.43 | saccharide | kanamycin | Streptomyces kanamyceticus
BGC0000131.5 |  | 0.43 | PKS | pyrrolomycin | Streptomyces sp. UC 11065
BGC0000234.5 |  | 0.42 | PKS | jadomycin | Streptomyces venezuelae ATCC 10712
BGC0001103.5 |  | 0.42 | NRPS, PKS | mycosubtilin | Bacillus subtilis subsp. spizizenii ATCC 6633
BGC0001095.5 |  | 0.41 | NRPS | fengycin | Bacillus velezensis FZB42
BGC0001464.3 |  | 0.40 | other (other) | tetrabromopyrrole | Pseudoalteromonas sp. PS5
BGC0001463.4 |  | 0.40 | other (other) | 2,3,4,5-tetrabromopyrrole | Pseudoalteromonas piscicida
BGC0000003.3 |  | 0.39 | PKS | AF-toxin | Alternaria alternata

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001166.5 |  | 0.55 | NRPS | HC-toxin | Alternaria jesenskae
BGC0002284.3 |  | 0.51 | other (other) | corynecin III, corynecin I, corynecin II | Rhodococcus sp. H-CA8f
BGC0000706.3 |  | 0.43 | saccharide | kanamycin | Streptomyces kanamyceticus
BGC0000131.5 |  | 0.43 | PKS | pyrrolomycin | Streptomyces sp. UC 11065
BGC0000234.5 |  | 0.42 | PKS | jadomycin | Streptomyces venezuelae ATCC 10712
BGC0001103.5 |  | 0.42 | NRPS, PKS | mycosubtilin | Bacillus subtilis subsp. spizizenii ATCC 6633
BGC0001095.5 |  | 0.41 | NRPS | fengycin | Bacillus velezensis FZB42
BGC0001464.3 |  | 0.40 | other (other) | tetrabromopyrrole | Pseudoalteromonas sp. PS5
BGC0001463.4 |  | 0.40 | other (other) | 2,3,4,5-tetrabromopyrrole | Pseudoalteromonas piscicida
BGC0000003.3 |  | 0.39 | PKS | AF-toxin | Alternaria alternata

Similar known clusters from MIBiG 4.0
Shows clusters from the MIBiG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.
Click on an accession to open that entry in the MIBiG database.
Location:
Identifier
Identity
Coverage
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.

No significant matches found.

Transcription Factor Binding Sites
Detailed information for Transcription Factor Binding Site hits, including surrounding genes where applicable.
The strand of the match is shown by an arrow underneath the match.
Detailed documentation is available here.
Binding sites found:
MogR
Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 24.21 out of 26.06
Confidence: strong
MogR
Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 22.93 out of 26.06
Confidence: medium
RpoN
Description: Regulator of nitrogen assimilation and virulence
Species: Salmonella & Vibrio sp.
Score: 16.06 out of 18.46
Confidence: medium
MogR
Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 23.23 out of 26.06
Confidence: medium
CodY
Description: Regulator of stationary phase and virulence in Gram-positive bacteria
Species: Bacillus, Lactococcus & Streptococcus sp.
Score: 22.67 out of 27.78
Confidence: medium
ArcA
Description: Repressor of carbon oxidation
Species: Escherichia coli str. K-12 substr. MG1655
Score: 19.83 out of 21.55
Confidence: medium
ZuR variant 1
Description: Zinc-responsive repressor
Species: Streptomyces coelicolor
Score: 22.40 out of 28.19
Confidence: medium
Additional weak hits (5):
CopR
Description: Copper-responsive regulator
Species: Lactococcus lactis subsp. lactis Il1403
Score: 26.05 out of 30.97
Confidence: weak
DasR
Description: N-acetylglucosamine dependent repressor
Species: Streptomyces coelicolor
Score: 20.10 out of 27.04
Confidence: weak
GnfM
Description: Regulator of nitrogen-fixation genes
Species: Geobacter sulfurreducens PCA
Score: 20.81 out of 27.55
Confidence: weak
LuxO
Description: Repressor of luminescence
Species: Vibrio campbellii ATCC BAA-1116
Score: 21.78 out of 26.12
Confidence: weak
NrtR
Description: NAD synthesis repressor
Species: Streptomyces coelicolor
Score: 24.03 out of 35.63
Confidence: weak
TFBS Finder
TFBS definitions
Shows descriptions for Transcription Factor Binding Site models

Regulator | Description
--- | ---
ArcA | Repressor of carbon oxidation
CodY | Regulator of stationary phase and virulence in Gram-positive bacteria
MogR | Repressor of flagellar motility genes
RpoN | Regulator of nitrogen assimilation and virulence
ZuR variant 1 | Zinc-responsive repressor

NZ_JAGKQT010000003.1 - Region 1 - terpene-precursor
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 444,197 - 465,075 nt. (total: 20,879 nt) Show pHMM detection rules used
terpene-precursor: (PT_FPPS_like and not PT_HPP)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
binding site
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
Tailoring
MIBiG comparison
KnownClusterBlast
SubClusterBlast
Terpene
TFBS Finder
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Tailoring functions
Tailoring enzymes detected in this region
Transferases: carboxylase
J2M30_RS03125: acetyl-CoA carboxylase biotin carboxylase

smcogs
  SMCOG1090: acetyl-CoA carboxylase biotin carboxylase

Ligases: synthase synthetase
J2M30_RS03155: Polyprenyl synthetase

smcogs
  SMCOG1182: Polyprenyl synthetase

J2M30_RS03160: 1-deoxy-D-xylulose-5-phosphate synthase

smcogs
  SMCOG1110: 1-deoxy-D-xylulose-5-phosphate synthase

Similar gene clusters
Shows areas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | terpene-precursor | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0002283.2 |  | 0.49 | terpene | sodorifen | Serratia plymuthica
BGC0001361.3 |  | 0.49 | terpene | sodorifen | Serratia plymuthica 4Rx13
BGC0002397.2 |  | 0.47 | terpene | astallatene | Arabidopsis thaliana
BGC0002400.2 |  | 0.44 | terpene | boleracene | Brassica oleracea var. oleracea
BGC0000665.5 |  | 0.39 | other (other), terpene | xiamycin, indosespene, sespenine, dixiamycin A, dixiamycin B, sulfadixiamycin A, sulfadixiamycin B, sulfadixiamycin C | Streptomyces sp. HKI0576
BGC0002398.2 |  | 0.39 | terpene | (-)-ent-quiannulatene | Arabidopsis thaliana
BGC0000668.5 |  | 0.38 | other (other), terpene | 12-epi-hapalindole C isonitrile, 12-epi-hapalindole E, 12-epi-fischerindole U isonitrile, fischerindole L, 12-epi-fischerindole I isonitrile, welwitindolinone A isonitrile, welwitindolinone B isothiocyanate, welwitindolinone C isothiocyanate, N-methylwelwitindolinone C isothiocyanate, N-methylwelwitinsolinone C isonitrile, 3-epi-welwitindolinone B isothiocyanate, 3-(Z-2'-isocyanoethenyl)-indole | Hapalosiphon welwitschii UTEX B 1830
BGC0000641.3 |  | 0.38 | terpene | carotenoid | Enterobacteriaceae bacterium DC416
BGC0002284.3 |  | 0.38 | other (other) | corynecin III, corynecin I, corynecin II | Rhodococcus sp. H-CA8f
BGC0000639.3 |  | 0.38 | terpene | carotenoid | Enterobacteriaceae bacterium DC260

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0002283.2 |  | 0.49 | terpene | sodorifen | Serratia plymuthica
BGC0001361.3 |  | 0.49 | terpene | sodorifen | Serratia plymuthica 4Rx13
BGC0002397.2 |  | 0.47 | terpene | astallatene | Arabidopsis thaliana
BGC0002400.2 |  | 0.44 | terpene | boleracene | Brassica oleracea var. oleracea
BGC0000665.5 |  | 0.39 | other (other), terpene | xiamycin, indosespene, sespenine, dixiamycin A, dixiamycin B, sulfadixiamycin A, sulfadixiamycin B, sulfadixiamycin C | Streptomyces sp. HKI0576
BGC0002398.2 |  | 0.39 | terpene | (-)-ent-quiannulatene | Arabidopsis thaliana
BGC0000668.5 |  | 0.38 | other (other), terpene | 12-epi-hapalindole C isonitrile, 12-epi-hapalindole E, 12-epi-fischerindole U isonitrile, fischerindole L, 12-epi-fischerindole I isonitrile, welwitindolinone A isonitrile, welwitindolinone B isothiocyanate, welwitindolinone C isothiocyanate, N-methylwelwitindolinone C isothiocyanate, N-methylwelwitinsolinone C isonitrile, 3-epi-welwitindolinone B isothiocyanate, 3-(Z-2'-isocyanoethenyl)-indole | Hapalosiphon welwitschii UTEX B 1830
BGC0000641.3 |  | 0.38 | terpene | carotenoid | Enterobacteriaceae bacterium DC416
BGC0002284.3 |  | 0.38 | other (other) | corynecin III, corynecin I, corynecin II | Rhodococcus sp. H-CA8f
BGC0000639.3 |  | 0.38 | terpene | carotenoid | Enterobacteriaceae bacterium DC260

Similar known clusters from MIBiG 4.0
Shows clusters from the MIBiG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.
Click on an accession to open that entry in the MIBiG database.
Location:
Identifier
Identity
Coverage
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.

No significant matches found.

Detailed terpene predictions
Detailed information for terpene domains. Shows possible products of a terpene cluster and lists the subtype and expected reactions for each terpene-related domain.
Product predictions:

Class | Subclass | Product name | Chain length | Initial cyclisations | Functional groups
--- | --- | --- | --- | --- | ---
sesquiterpene precursor |  | FPP | C15 | acyclic | PP

Genes with terpene domains:
J2M30_RS03155: PT_FPPS_like
Domain 1 (32 - 291): Prenyltransferase; Farnesyl diphosphate synthase like
Subtype: Farnesyl diphosphate synthase, bacterial

Reactions:
  IPP, DMAPP → FPP

Transcription Factor Binding Sites
Detailed information for Transcription Factor Binding Site hits, including surrounding genes where applicable.
The strand of the match is shown by an arrow underneath the match.
Detailed documentation is available here.
Binding sites found:
ToxT
Description: Regulator of MSHA biosynthesis
Species: Vibrio cholerae O395
Score: 18.57 out of 18.57
Confidence: strong
RpoN
Description: Regulator of nitrogen assimilation and virulence
Species: Salmonella & Vibrio sp.
Score: 16.73 out of 18.46
Confidence: medium
CodY
Description: Regulator of stationary phase and virulence in Gram-positive bacteria
Species: Bacillus, Lactococcus & Streptococcus sp.
Score: 23.50 out of 27.78
Confidence: medium
MogR
Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 22.90 out of 26.06
Confidence: medium
MogR
Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 23.73 out of 26.06
Confidence: medium
CcpA
Description: Catabolite control protein A
Species: Streptococcus & Clostridium sp.
Score: 19.77 out of 20.97
Confidence: strong
Additional weak hits (3):
CelR
Description: Cellobiose uptake repressor
Species: Streptomyces coelicolor
Score: 20.05 out of 30.11
Confidence: weak
CelR
Description: Cellobiose uptake repressor
Species: Streptomyces coelicolor
Score: 19.47 out of 30.11
Confidence: weak
HipB
Description: Bacterial antitoxin HipB
Species: Escherichia coli BL21(DE3)
Score: 22.70 out of 33.73
Confidence: weak
Terpene
TFBS Finder
Glossary
Glossary showing acronyms and their full names.

Acronym | Full name
--- | ---
DMAPP | Dimethylallyl diphosphate
FPP | Farnesyl diphosphate
IPP | Isopentenyl diphosphate
PP | Diphosphate

TFBS definitions
Shows descriptions for Transcription Factor Binding Site models

Regulator | Description
--- | ---
CcpA | Catabolite control protein A
CodY | Regulator of stationary phase and virulence in Gram-positive bacteria
MogR | Repressor of flagellar motility genes
RpoN | Regulator of nitrogen assimilation and virulence
ToxT | Regulator of MSHA biosynthesis

NZ_JAGKQT010000003.1 - Region 2 - lassopeptide
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 884,190 - 908,043 nt. (total: 23,854 nt) Show pHMM detection rules used
lassopeptide: (PF13471 and Asn_synthase or micJ25 or mcjC)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
binding site
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
Tailoring
MIBiG comparison
KnownClusterBlast
SubClusterBlast
Lasso peptides
TFBS Finder
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Tailoring functions
Tailoring enzymes detected in this region
Hydrolases: hydrolase
J2M30_RS05390: asparagine synthase (glutamine-hydrolyzing)

smcogs
  SMCOG1177: asparagine synthase (glutamine-hydrolyzing)

Similar gene clusters
Shows areas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | lassopeptide | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001356.4 |  | 0.70 | ribosomal | paeninodin | Paenibacillus dendritiformis C454
BGC0001634.3 |  | 0.53 | ribosomal | keywimysin | Streptomyces sp. NRRL F-5702
BGC0000571.3 |  | 0.50 | ribosomal | burhizin | Paraburkholderia rhizoxinica HKI 454
BGC0002322.3 |  | 0.47 | ribosomal | citrocin | Citrobacter pasteurii
BGC0001779.5 |  | 0.46 | ribosomal | siamycin | Streptomyces nodosus
BGC0000623.3 |  | 0.43 | ribosomal | plantaricin W α, plantaricin W β | Lactobacillus plantarum
BGC0001229.4 |  | 0.42 | ribosomal | SBI-06990 A1, SBI-06989 A2 | Streptomyces bingchenggensis BCW-1
BGC0000517.4 |  | 0.42 | ribosomal | haloduracin β, haloduracin α | Bacillus halodurans C-125
BGC0000513.3 |  | 0.42 | ribosomal | Ery-9, Ery-6, Ery-8, Ery-7, Ery-5, Ery-4, Ery-3 | Saccharopolyspora erythraea NRRL 2338
BGC0000617.5 |  | 0.40 | ribosomal | coagulin | Bacillus coagulans

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001356.4 |  | 0.70 | ribosomal | paeninodin | Paenibacillus dendritiformis C454
BGC0001634.3 |  | 0.53 | ribosomal | keywimysin | Streptomyces sp. NRRL F-5702
BGC0000571.3 |  | 0.50 | ribosomal | burhizin | Paraburkholderia rhizoxinica HKI 454
BGC0002322.3 |  | 0.47 | ribosomal | citrocin | Citrobacter pasteurii
BGC0001779.5 |  | 0.46 | ribosomal | siamycin | Streptomyces nodosus
BGC0000623.3 |  | 0.43 | ribosomal | plantaricin W α, plantaricin W β | Lactobacillus plantarum
BGC0001229.4 |  | 0.42 | ribosomal | SBI-06990 A1, SBI-06989 A2 | Streptomyces bingchenggensis BCW-1
BGC0000517.4 |  | 0.42 | ribosomal | haloduracin β, haloduracin α | Bacillus halodurans C-125
BGC0000513.3 |  | 0.42 | ribosomal | Ery-9, Ery-6, Ery-8, Ery-7, Ery-5, Ery-4, Ery-3 | Saccharopolyspora erythraea NRRL 2338
BGC0000617.5 |  | 0.40 | ribosomal | coagulin | Bacillus coagulans

Similar known clusters from MIBiG 4.0
Shows clusters from the MIBiG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.
Click on an accession to open that entry in the MIBiG database.
Location:
Identifier
Identity
Coverage
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.

No significant matches found.

Lasso peptide predictions
Lists the possible core peptides for each biosynthetic enzyme. Each core peptide shows the leader and core peptide sequences.
Includes CompaRiPPson results for any available databases, with a detailed explanation here.
Lassopeptides - No core peptides found.
Transcription Factor Binding Sites
Detailed information for Transcription Factor Binding Site hits, including surrounding genes where applicable.
The strand of the match is shown by an arrow underneath the match.
Detailed documentation is available here.
Binding sites found:
MogR
Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 24.21 out of 26.06
Confidence: strong
MogR
Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 24.03 out of 26.06
Confidence: strong
MogR
Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 22.93 out of 26.06
Confidence: medium
MogR
Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 22.64 out of 26.06
Confidence: medium
CodY
Description: Regulator of stationary phase and virulence in Gram-positive bacteria
Species: Bacillus, Lactococcus & Streptococcus sp.
Score: 25.98 out of 27.78
Confidence: strong
ANR
Description: Anaerobic transcriptional regulator
Species: Pseudomonas putida KT2440
Score: 21.28 out of 26.33
Confidence: medium
ZuR variant 1
Description: Zinc-responsive repressor
Species: Streptomyces coelicolor
Score: 26.93 out of 28.19
Confidence: strong
LexA variant 2
Description: Repressor of DNA damage response
Species: Bacillus subtilis subsp. subtilis str. 168
Score: 20.09 out of 24.78
Confidence: medium
Additional weak hits (2):
DosR
Description: Hypoxia stress response regulator
Species: Mycobacterium tuberculosis H37Rv
Score: 21.67 out of 29.51
Confidence: weak
MatP
Description: Cell cycle regulator
Species: Escherichia coli str. K-12 substr. MG1655
Score: 19.63 out of 25.75
Confidence: weak
Lasso peptides
RREFinder
TFBS Finder
Core peptide predictions
Lists the possible core peptides in the region. Each core peptide lists the number of disulfide bridges, possible molecular weights, and the scores for cleavage site prediction and RODEO.
No core peptides found.
RRE predictions
RREfinder results sidepanel.

lassopeptide protocluster (884189...908043)
J2M30_RS05405
  RRE type: Stand_Alone_Lasso_RRE
  Location: 0 - 72
  Score: 77.2

TFBS definitions
Shows descriptions for Transcription Factor Binding Site models

Regulator | Description
--- | ---
ANR | Anaerobic transcriptional regulator
CodY | Regulator of stationary phase and virulence in Gram-positive bacteria
LexA variant 2 | Repressor of DNA damage response
MogR | Repressor of flagellar motility genes
ZuR variant 1 | Zinc-responsive repressor

NZ_JAGKQT010000003.1 - Region 3 - NRP-metallophore,NRPS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 926,942 - 978,576 nt. (total: 51,635 nt) Show pHMM detection rules used
NRP-metallophore: (VibH_like or Cy_tandem or (cds(Condensation and AMP-binding) and ((IBH_Asp and not SBH_Asp) or IBH_His or TBH_Asp or CyanoBH_Asp1 or CyanoBH_Asp2 or IPL or SalSyn or (EntA and EntC) or (GrbD and GrbE) or (FbnL and FbnM) or PvdO or PvdP or (Orn_monoox and not (KtzT or MetRS-like)) or Lys_monoox or VbsL)))
NRPS: cds(Condensation and (AMP-binding or A-OX) and not alpha_am_amid)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
binding site
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
Tailoring
MIBiG comparison
KnownClusterBlast
SubClusterBlast
TFBS Finder
NRPS/PKS modules
NRPS/PKS domains
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Tailoring functions
Tailoring enzymes detected in this region
Oxidoreductases: dehydrogenase
J2M30_RS05725: short-chain dehydrogenase/reductase SDR

smcogs
  SMCOG1001: short-chain dehydrogenase/reductase SDR

Transferases: PPTase acetyltransferase aminotransferase
J2M30_RS05675: acetyl-CoA acetyltransferase

smcogs
  SMCOG1124: acetyl-CoA acetyltransferase

J2M30_RS05760: 4'-phosphopantetheinyl transferase

smcogs
  SMCOG1012: 4'-phosphopantetheinyl transferase

J2M30_RS05775: aminotransferase

smcogs
  SMCOG1019: aminotransferase

Hydrolases: hydrolase
J2M30_RS05740: isochorismatase

smcogs
  SMCOG1027: isochorismatase

Isomerases: isomerase mutase
J2M30_RS05730: isochorismate synthase

smcogs
  SMCOG1018: isochorismate synthase

J2M30_RS05790: phosphoglycerate mutase

smcogs
  SMCOG1101: phosphoglycerate mutase

Ligases: ligase synthase
J2M30_RS05680: AMP-dependent synthetase and ligase

smcogs
  SMCOG1002: AMP-dependent synthetase and ligase

J2M30_RS05735: AMP-dependent synthetase and ligase

smcogs
  SMCOG1002: AMP-dependent synthetase and ligase

J2M30_RS05745: condensation domain-containing protein

smcogs
  SMCOG1127: condensation domain-containing protein

J2M30_RS05820: cobalamin synthesis protein/P47K family protein

smcogs
  SMCOG1178: cobalamin synthesis protein/P47K family protein

Similar gene clusters
Shows areas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | NRP-metallophore | NRPS | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | --- | ---
BGC0001185.5 |  |  | 1.02 | NRPS | bacillibactin | Bacillus velezensis FZB42
BGC0000309.5 |  |  | 0.88 | NRPS | bacillibactin | Bacillus subtilis subsp. subtilis str. 168
BGC0000401.5 |  |  | 0.86 | NRPS | paenibactin | Paenibacillus elgii B69
BGC0002695.2 |  |  | 0.78 | NRPS | bacillibactin, bacillibactin E, bacillibactin F | Bacillus sp. WMMC1349
BGC0001132.4 |  |  | 0.76 | NRPS | xenotetrapeptide | Xenorhabdus nematophila ATCC 19061
BGC0001833.4 |  |  | 0.75 | NRPS | icosalide A, icosalide B | Burkholderia gladioli
BGC0001825.4 |  |  | 0.74 | NRPS | xenematide | Xenorhabdus nematophila AN6/1
BGC0001128.4 |  |  | 0.73 | NRPS | gamexpeptide C | Photorhabdus laumondii subsp. laumondii TTO1
BGC0002286.3 |  |  | 0.71 | NRPS | ririwpeptide A, ririwpeptide B, ririwpeptide C | Photorhabdus laumondii subsp. laumondii TTO1
BGC0001758.4 |  |  | 0.71 | NRPS | rhizomide A, rhizomide B, rhizomide C | Paraburkholderia rhizoxinica HKI 454

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001185.5 |  | 0.79 | NRPS | bacillibactin | Bacillus velezensis FZB42
BGC0000309.5 |  | 0.75 | NRPS | bacillibactin | Bacillus subtilis subsp. subtilis str. 168
BGC0000401.5 |  | 0.74 | NRPS | paenibactin | Paenibacillus elgii B69
BGC0002695.2 |  | 0.71 | NRPS | bacillibactin, bacillibactin E, bacillibactin F | Bacillus sp. WMMC1349
BGC0001132.4 |  | 0.70 | NRPS | xenotetrapeptide | Xenorhabdus nematophila ATCC 19061
BGC0001833.4 |  | 0.70 | NRPS | icosalide A, icosalide B | Burkholderia gladioli
BGC0001825.4 |  | 0.70 | NRPS | xenematide | Xenorhabdus nematophila AN6/1
BGC0001128.4 |  | 0.69 | NRPS | gamexpeptide C | Photorhabdus laumondii subsp. laumondii TTO1
BGC0002286.3 |  | 0.68 | NRPS | ririwpeptide A, ririwpeptide B, ririwpeptide C | Photorhabdus laumondii subsp. laumondii TTO1
BGC0001758.4 |  | 0.68 | NRPS | rhizomide A, rhizomide B, rhizomide C | Paraburkholderia rhizoxinica HKI 454

Similar known clusters from MIBiG 4.0
Shows clusters from the MIBiG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.
Click on an accession to open that entry in the MIBiG database.
Location:
Identifier
Identity
Coverage
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.

No significant matches found.

Transcription Factor Binding Sites
Detailed information for Transcription Factor Binding Site hits, including surrounding genes where applicable.
The strand of the match is shown by an arrow underneath the match.
Detailed documentation is available here.
Binding sites found:
MogR
Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 25.47 out of 26.06
Confidence: strong
FuR variant 1
Description: Ferric Uptake Regulator
Species: Bacillus, Pseudomonas, Yersinia sp.
Score: 26.54 out of 29.38
Confidence: strong
FuR variant 1
Description: Ferric Uptake Regulator
Species: Bacillus, Pseudomonas, Yersinia sp.
Score: 27.77 out of 29.38
Confidence: strong
ZuR variant 1
Description: Zinc-responsive repressor
Species: Streptomyces coelicolor
Score: 24.73 out of 28.19
Confidence: strong
AfsR
Description: Pleiotropic regulatory for antibiotic production
Species: Streptomyces coelicolor
Score: 19.59 out of 23.05
Confidence: medium
FuR variant 1
Description: Ferric Uptake Regulator
Species: Bacillus, Pseudomonas, Yersinia sp.
Score: 25.36 out of 29.38
Confidence: medium
FuR variant 1
Description: Ferric Uptake Regulator
Species: Bacillus, Pseudomonas, Yersinia sp.
Score: 24.91 out of 29.38
Confidence: medium
SypG
Description: Regulator of biofilm formation and host colonization
Species: Vibrio fischeri ES114
Score: 22.76 out of 29.25
Confidence: medium
MogR
Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 22.64 out of 26.06
Confidence: medium
CodY
Description: Regulator of stationary phase and virulence in Gram-positive bacteria
Species: Bacillus, Lactococcus & Streptococcus sp.
Score: 23.28 out of 27.78
Confidence: medium
MogR
Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 22.34 out of 26.06
Confidence: medium
ZuR variant 1
Description: Zinc-responsive repressor
Species: Streptomyces coelicolor
Score: 22.98 out of 28.19
Confidence: medium
Additional weak hits (11):
ClgR
Description: Caseinolytic protease gene regulator
Species: Corynebacterium glutamicum ATCC 13032
Score: 21.50 out of 30.22
Confidence: weak
CelR
Description: Cellobiose uptake repressor
Species: Streptomyces coelicolor
Score: 21.22 out of 30.11
Confidence: weak
CelR
Description: Cellobiose uptake repressor
Species: Streptomyces coelicolor
Score: 19.74 out of 30.11
Confidence: weak
FuR variant 1
Description: Ferric Uptake Regulator
Species: Bacillus, Pseudomonas, Yersinia sp.
Score: 23.61 out of 29.38
Confidence: weak
FuR variant 2
Description: Ferric Uptake Regulator
Species: Caulobacter crescentus CB15
Score: 23.50 out of 32.74
Confidence: weak
FuR variant 1
Description: Ferric Uptake Regulator
Species: Bacillus, Pseudomonas, Yersinia sp.
Score: 23.49 out of 29.38
Confidence: weak
FuR variant 2
Description: Ferric Uptake Regulator
Species: Caulobacter crescentus CB15
Score: 23.38 out of 32.74
Confidence: weak
FuR variant 1
Description: Ferric Uptake Regulator
Species: Bacillus, Pseudomonas, Yersinia sp.
Score: 23.62 out of 29.38
Confidence: weak
SypG
Description: Regulator of biofilm formation and host colonization
Species: Vibrio fischeri ES114
Score: 22.33 out of 29.25
Confidence: weak
ColR
Description: Phenol-responsive regulator
Species: Pseudomonas putida KT2440
Score: 22.30 out of 30.25
Confidence: weak
ZuR variant 2
Description: Zinc-responsive repressor
Species: Pseudomonas protegens Pf-5
Score: 23.82 out of 33.14
Confidence: weak
Module view
Shows module structures for each candidate cluster in NRPS and PKS regions.
Genes are shown in predicted order, and are only present when containing at least one complete module.
A domain glossary is available here, and an explanation of the visualisation is available here.
Legend
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A domain glossary is available here, and an explanation of the visualisation is available here.
Selected features only
Show module domains
NRPS/PKS products
NRPS/PKS substrates
TFBS Finder
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 3, location 926941 - 978576:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:
  (Gly - Thr)

Direct lookup in NORINE database: strict or relaxed
Link to NORINE database query form
NRPS/PKS substrate predictions
Shows the predicted substrates for each adenylation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
J2M30_RS05680: X
AMP-binding (7..381): X
nrpys: Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr

SVM prediction details:
  Predicted physicochemical class:
    hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
  Large clusters prediction:
    N/A
  Small clusters prediction:
    N/A
  Single AA prediction:
    N/A

Stachelhaus prediction details:
  Stachelhaus sequence:
    SCNGHSLFLYGSYSLSSGAYEFYGASELSFVSVL
  Nearest Stachelhaus code(s):
  Stachelhaus code match:
    0% (weak)

J2M30_RS05735: diOH-Bz
Search NORINE for peptide: strict or relaxed
AMP-binding (30..435): diOH-Bz
nrpys: diOH-Bz

SVM prediction details:
  Predicted physicochemical class:
    hydrophobic-aromatic (Phe, Tyr, diOH-Bz, Ph-Gly, bOH-Tyr)
  Large clusters prediction:
    Hydroxy-benzoic acid derivates (diOH-Bz, Sal)
  Small clusters prediction:
    Hydroxy-benzoic acid derivates (diOH-Bz, Sal)
  Single AA prediction:
    dhb (diOH-Bz)

Stachelhaus prediction details:
  Stachelhaus sequence:
    SKSLYPLSSPGGGVQVGGAQQVYGMAEGLVNYTR
  Nearest Stachelhaus code(s):
    diOH-Bz PLPAQGVVNK (88% 8Å match)
  Stachelhaus code match:
    90% (moderate)

J2M30_RS05745: Gly - Thr
Search NORINE for peptide: strict or relaxed
AMP-binding (461..858): Gly
nrpys: Gly

SVM prediction details:
  Predicted physicochemical class:
    hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
  Large clusters prediction:
    Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)
  Small clusters prediction:
    Tiny, hydrophilic, transition to aliphatic (Gly, Ala)
  Single AA prediction:
    gly (Gly)

Stachelhaus prediction details:
  Stachelhaus sequence:
    FAMTFDISALELQALVGGETNFYGPTETTIWSSS
  Nearest Stachelhaus code(s):
    Gly DILQLGLIWK (91% 8Å match)
  Stachelhaus code match:
    90% (moderate)

AMP-binding (1509..1920): Thr
nrpys: Thr

SVM prediction details:
  Predicted physicochemical class:
    hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
  Large clusters prediction:
    Aliphatic chain or phenyl group with -OH (Ser, Thr, Dhpg, Hpg)
  Small clusters prediction:
    thr (Thr)
  Single AA prediction:
    thr (Thr)

Stachelhaus prediction details:
  Stachelhaus sequence:
    LSTHFDFSVWEGNQIFGGEINMYGITETTVHVSF
  Nearest Stachelhaus code(s):
    Thr DFWNIGMVHK (94% 8Å match)
  Stachelhaus code match:
    100% (strong)

Link to PARAS substrate predictor
TFBS definitions
Shows descriptions for Transcription Factor Binding Site models

Regulator | Description
--- | ---
AfsR | Pleiotropic regulatory for antibiotic production
CodY | Regulator of stationary phase and virulence in Gram-positive bacteria
FuR variant 1 | Ferric Uptake Regulator
MogR | Repressor of flagellar motility genes
SypG | Regulator of biofilm formation and host colonization
ZuR variant 1 | Zinc-responsive repressor

NZ_JAGKQT010000001.1 - Region 1 - azole-containing-RiPP
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 46,148 - 69,693 nt. (total: 23,546 nt) Show pHMM detection rules used
azole-containing-RiPP: ((YcaO or TIGR03604) and (((thio_amide and (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or TIGR03603 or thiostrepton or TIGR03602)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
binding site
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
Tailoring
MIBiG comparison
KnownClusterBlast
SubClusterBlast
TFBS Finder
Azole RiPPs
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Tailoring functions
Tailoring enzymes detected in this region
Oxidoreductases: dehydrogenase
J2M30_RS00380: alcohol dehydrogenase

smcogs
  SMCOG1040: alcohol dehydrogenase

J2M30_RS00395: short-chain dehydrogenase/reductase SDR

smcogs
  SMCOG1001: short-chain dehydrogenase/reductase SDR

Transferases: kinase
J2M30_RS00390: PfkB domain protein

smcogs
  SMCOG1276: PfkB domain protein

Similar gene clusters
Shows areas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | azole-containing-RiPP | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001928.2 |  | 0.47 | other (other) | (2R,3S,4S)-5-fluoro-2,3,4-trihydroxypentanoic acid | Streptomyces sp. MA37
BGC0002496.3 |  | 0.45 | NRPS | serratiochelin A, serratiochelin C, serratiochelin B | Serratia plymuthica
BGC0001174.4 |  | 0.44 | ribosomal | corynazolicin | Corynebacterium urealyticum DSM 7111
BGC0000569.5 |  | 0.43 | ribosomal | plantazolicin | Bacillus velezensis FZB42
BGC0001173.5 |  | 0.43 | ribosomal | plantazolicin | Bacillus pumilus ATCC 7061
BGC0000607.5 |  | 0.43 | ribosomal | micrococcin P1 | Macrococcus caseolyticus
BGC0000558.5 |  | 0.42 | ribosomal | sublancin 168 | Bacillus subtilis subsp. subtilis str. 168
BGC0001229.4 |  | 0.42 | ribosomal | SBI-06990 A1, SBI-06989 A2 | Streptomyces bingchenggensis BCW-1
BGC0001146.5 |  | 0.41 | ribosomal | cyclothiazomycin C | Streptomyces sp. NRRL WC-3908
BGC0002116.3 |  | 0.41 | ribosomal | darobactin A | Photorhabdus khanii HGB 1456

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001928.2 |  | 0.47 | other (other) | (2R,3S,4S)-5-fluoro-2,3,4-trihydroxypentanoic acid | Streptomyces sp. MA37
BGC0002496.3 |  | 0.45 | NRPS | serratiochelin A, serratiochelin C, serratiochelin B | Serratia plymuthica
BGC0001174.4 |  | 0.44 | ribosomal | corynazolicin | Corynebacterium urealyticum DSM 7111
BGC0000569.5 |  | 0.43 | ribosomal | plantazolicin | Bacillus velezensis FZB42
BGC0001173.5 |  | 0.43 | ribosomal | plantazolicin | Bacillus pumilus ATCC 7061
BGC0000607.5 |  | 0.43 | ribosomal | micrococcin P1 | Macrococcus caseolyticus
BGC0000558.5 |  | 0.42 | ribosomal | sublancin 168 | Bacillus subtilis subsp. subtilis str. 168
BGC0001229.4 |  | 0.42 | ribosomal | SBI-06990 A1, SBI-06989 A2 | Streptomyces bingchenggensis BCW-1
BGC0001146.5 |  | 0.41 | ribosomal | cyclothiazomycin C | Streptomyces sp. NRRL WC-3908
BGC0002116.3 |  | 0.41 | ribosomal | darobactin A | Photorhabdus khanii HGB 1456

Similar known clusters from MIBiG 4.0
Shows clusters from the MIBiG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.
Click on an accession to open that entry in the MIBiG database.

No significant matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.

No significant matches found.

Transcription Factor Binding Sites
Detailed information for Transcription Factor Binding Site hits, including surrounding genes where applicable.
The strand of the match is shown by an arrow underneath the match.
Detailed documentation is available here.
Binding sites found:
NtrC
Description: Nitrogen regulatory protein C
Species: Pseudomonas putida KT2440
Score: 21.87 out of 29.72
Confidence: medium
MogR
Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 22.16 out of 26.06
Confidence: medium
LexA variant 3
Description: Repressor of DNA damage response
Species: Escherichia coli str. K-12 substr. MG1655
Score: 27.70 out of 32.93
Confidence: medium
Additional weak hits (4):
ClgR
Description: Caseinolytic protease gene regulator
Species: Corynebacterium glutamicum ATCC 13032
Score: 20.33 out of 30.22
Confidence: weak
LuxO
Description: Repressor of luminescence
Species: Vibrio campbellii ATCC BAA-1116
Score: 20.68 out of 26.12
Confidence: weak
CopR
Description: Copper-responsive regulator
Species: Lactococcus lactis subsp. lactis Il1403
Score: 23.25 out of 30.97
Confidence: weak
SypG
Description: Regulator of biofilm formation and host colonization
Species: Vibrio fischeri ES114
Score: 22.33 out of 29.25
Confidence: weak
(Thi)azol(in)e containing peptide predictions
Lists the possible core peptides for each biosynthetic enzyme. Predicted tail sequences are also shown, if present.
Includes CompaRiPPson results for any available databases, with a detailed explanation here.
No core peptides found.
RREFinder
TFBS Finder
Azole RiPPs
RRE predictions
RREfinder results sidepanel.

azole-containing-RiPP protocluster (46147...69693)
J2M30_RS00350
  RRE type: Heterocycloanthracin_C_RRE
  Location: 0 - 99
  Score: 164.2
  RRE type: Thiopeptide_F_RRE
  Location: 7 - 88
  Score: 48.7

TFBS definitions
Shows descriptions for Transcription Factor Binding Site models

Regulator | Description
--- | ---
LexA variant 3 | Repressor of DNA damage response
MogR | Repressor of flagellar motility genes
NtrC | Nitrogen regulatory protein C

Core peptide predictions
Lists the possible core peptides in the region. Each core peptide lists its possible molecular weights and the scores for cleavage site prediction and RODEO. If relevant, other features, such as macrocycle and amidation, will also be listed.
No core peptides found.
NZ_JAGKQT010000007.1 - Region 1 - cyclic-lactone-autoinducer,lanthipeptide-class-ii
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 70,661 - 100,236 nt. (total: 29,576 nt) Show pHMM detection rules used
lanthipeptide-class-ii: cds(LANC_like and DUF4135)
cyclic-lactone-autoinducer: (TIGR04223 or AgrB)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
binding site
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
Tailoring
MIBiG comparison
KnownClusterBlast
SubClusterBlast
Lanthipeptides
TFBS Finder
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Tailoring functions
Tailoring enzymes detected in this region
Oxidoreductases: dehydrogenase oxidoreductase
J2M30_RS09815: aldehyde dehydrogenase

smcogs
  SMCOG1017: aldehyde dehydrogenase

J2M30_RS09890: aldo/keto reductase family oxidoreductase

smcogs
  SMCOG1039: aldo/keto reductase family oxidoreductase

J2M30_RS09895: dihydropteridine reductase

smcogs
  SMCOG1159: dihydropteridine reductase

Transferases: kinase
J2M30_RS09795: PfkB domain protein

smcogs
  SMCOG1276: PfkB domain protein

Lyases: cyclase
J2M30_RS09840: lanthionine synthetase C family protein

smcogs
  SMCOG1070: lanthionine synthetase C family protein

J2M30_RS09850: lanthionine synthetase C family protein

smcogs
  SMCOG1070: lanthionine synthetase C family protein

Similar gene clusters
Shows areas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | lanthipeptide-class-ii | cyclic-lactone-autoinducer | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | --- | ---
BGC0001391.3 |  |  | 0.72 | ribosomal | thusin | Bacillus thuringiensis serovar rongseni
BGC0000517.4 |  |  | 0.50 | ribosomal | haloduracin β, haloduracin α | Bacillus halodurans C-125
BGC0000555.3 |  |  | 0.43 | ribosomal | staphylococcin C55 α, staphylococcin C55 β | Staphylococcus aureus
BGC0001311.5 |  |  | 0.43 | ribosomal | flavecins | Ruminococcus flavefaciens FD-1
BGC0000516.4 |  |  | 0.42 | ribosomal | geobacillin II | Geobacillus thermodenitrificans
BGC0000623.3 |  |  | 0.42 | ribosomal | plantaricin W α, plantaricin W β | Lactobacillus plantarum
BGC0000552.3 |  |  | 0.42 | ribosomal | SmbA, SmbB | Streptococcus mutans
BGC0001210.5 |  |  | 0.41 | ribosomal | pseudomycoicidin | Bacillus pseudomycoides DSM 12442
BGC0001229.4 |  |  | 0.40 | ribosomal | SBI-06990 A1, SBI-06989 A2 | Streptomyces bingchenggensis BCW-1
BGC0000497.3 |  |  | 0.40 | ribosomal | BHT-Aα, BHT-Aβ | Streptococcus ratti

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001391.3 |  | 0.69 | ribosomal | thusin | Bacillus thuringiensis serovar rongseni
BGC0000517.4 |  | 0.59 | ribosomal | haloduracin β, haloduracin α | Bacillus halodurans C-125
BGC0000516.4 |  | 0.55 | ribosomal | geobacillin II | Geobacillus thermodenitrificans
BGC0000555.3 |  | 0.54 | ribosomal | staphylococcin C55 α, staphylococcin C55 β | Staphylococcus aureus
BGC0001311.5 |  | 0.54 | ribosomal | flavecins | Ruminococcus flavefaciens FD-1
BGC0000623.3 |  | 0.54 | ribosomal | plantaricin W α, plantaricin W β | Lactobacillus plantarum
BGC0000552.3 |  | 0.54 | ribosomal | SmbA, SmbB | Streptococcus mutans
BGC0001210.5 |  | 0.53 | ribosomal | pseudomycoicidin | Bacillus pseudomycoides DSM 12442
BGC0001229.4 |  | 0.53 | ribosomal | SBI-06990 A1, SBI-06989 A2 | Streptomyces bingchenggensis BCW-1
BGC0000497.3 |  | 0.52 | ribosomal | BHT-Aα, BHT-Aβ | Streptococcus ratti

Similar known clusters from MIBiG 4.0
Shows clusters from the MIBiG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.
Click on an accession to open that entry in the MIBiG database.
Location:
Identifier
Identity
Coverage
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.

No significant matches found.

Lanthipeptide predictions
Shows the possible core peptides for each biosynthetic enzyme.
Includes CompaRiPPson results for any available databases, with a detailed explanation here.

#### Lanthipeptide(s) for J2M30_RS09840

J2M30_RS09845
Leader:
MKNMKELEKVTGLISEEELDQDLSEVNGA
Core:
G T P A I F S A I S A I T A V T V Q S P C P T S A C S K S C
Core with dehydrations:
G Dhb P A I F Dha A I Dha A I Dhb A V Dhb V Q Dha P Cys P Dhb Dha A Cys Dha K Dha Cys

#### antiSMASH-DB 4.0 matches for J2M30_RS09845

100.0%
NZ_JAGKQT010000007.1 and 3 others:
NZ_JAGKQT010000007.1 Lanthipeptides: J2M30_RS09845_lanthipeptide NZ_LVYL01000010.1 Lanthipeptides: A3863_RS05870_lanthipeptide NZ_LVYL01000010.1 Lanthipeptides: A3863_RS05870_lanthipeptide
Lanthipeptides: J2M30_RS09845_lanthipeptide
1
G T P A I F S A I S A I T A V T V Q S P C P T S A C S K S C
30
G T P A I F S A I S A I T A V T V Q S P C P T S A C S K S C
1
G T P A I F S A I S A I T A V T V Q S P C P T S A C S K S C
30
70.3%
NZ_CM000756.1 and 17 others:
NZ_CM000756.1 Lanthipeptides: BTHUR0011_RS14760_lanthipeptide NZ_CM000756.1 Lanthipeptides: BTHUR0011_RS14765_lanthipeptide NZ_CM000756.1 Lanthipeptides: BTHUR0011_RS14760_lanthipeptide NZ_CP031749.1 Lanthipeptides: DPQ26_RS29740_lanthipeptide NZ_CP031749.1 Lanthipeptides: DPQ26_RS29735_lanthipeptide NZ_CP031749.1 Lanthipeptides: DPQ26_RS29730_lanthipeptide NZ_CP031749.1 Lanthipeptides: DPQ26_RS29740_lanthipeptide NZ_CP031749.1 Lanthipeptides: DPQ26_RS29735_lanthipeptide NZ_CP031749.1 Lanthipeptides: DPQ26_RS29730_lanthipeptide NZ_CP036071.1 Lanthipeptides: EXW41_RS26900_lanthipeptide NZ_CP036071.1 Lanthipeptides: EXW41_RS26895_lanthipeptide NZ_CP036071.1 Lanthipeptides: EXW41_RS26900_lanthipeptide NZ_CP036071.1 Lanthipeptides: EXW41_RS26895_lanthipeptide NZ_WBPC01000036.1 Lanthipeptides: F8159_RS22545_lanthipeptide NZ_WBPC01000036.1 Lanthipeptides: F8159_RS22540_lanthipeptide NZ_WBPC01000036.1 Lanthipeptides: F8159_RS22545_lanthipeptide NZ_WBPC01000036.1 Lanthipeptides: F8159_RS22540_lanthipeptide
Lanthipeptides: BTHUR0011_RS14765_lanthipeptide
1
G T P A I F S A I S A I T A V T V Q S P C P T S A C S K S C
30
G T P A I +A I S A+T A V T Q S P C P T S A C S K S C
6
G T P A I V T A I S A V T A V T A Q S P C P T S A C S K S C
35
43.3%
NZ_PCGR01000003.1 and 1 other:
NZ_PCGR01000003.1 Lanthipeptides: CQS04_RS09625_lanthipeptide
Lanthipeptides: CQS04_RS09625_lanthipeptide
2
T P A I F S A I S A I T A V T V Q S P C P T S A C S K S C
30
T P I I+A I T + C P T+A C+++C
2
T P T I V--I T A I T G Y I S A N S C P T T A C T R A C
28
with 60 more sequence matches
Only the first 10 are displayed here.
42.1%
NC_006322.1 and 7 others:
NC_006322.1 Lanthipeptides: BLI_RS20290_lanthipeptide NZ_CP033218.1 Lanthipeptides: D9Y32_RS07810_lanthipeptide NZ_CP033218.1 Lanthipeptides: D9Y32_RS07810_lanthipeptide NZ_LQYL01000021.1 Lanthipeptides: B4090_RS08830_lanthipeptide NZ_LQYL01000021.1 Lanthipeptides: B4090_RS08830_lanthipeptide NZ_NIMP01000036.1 Lanthipeptides: CHCC14566_RS11870_lanthipeptide NZ_NIMP01000036.1 Lanthipeptides: CHCC14566_RS11870_lanthipeptide
Lanthipeptides: BLI_RS20290_lanthipeptide
2
T P A I F S A I S A I T A-V T V Q-S P C P T S A C S K S C
30
T P A S+ + I T A V T V S C P T+ C+ C
8
T P A T T S S W T C I T A G V T V S A S L C P T T K C T S R C
38
41.9%
NZ_AP026714.1 and 21 others:
NZ_AP026714.1 Lanthipeptides: PO853_RS06520_lanthipeptide NZ_CP028724.1 Lanthipeptides: C7I31_RS11270_lanthipeptide NZ_CP028724.1 Lanthipeptides: C7I31_RS11270_lanthipeptide NZ_CP092907.1 Lanthipeptides: MK744_RS03990_lanthipeptide NZ_CP092907.1 Lanthipeptides: MK744_RS03990_lanthipeptide NZ_KB944759.1 Lanthipeptides: WOA_RS09815_lanthipeptide NZ_KB944759.1 Lanthipeptides: WOA_RS09815_lanthipeptide NZ_KZ845892.1 Lanthipeptides: EB42_RS00090_lanthipeptide NZ_KZ845892.1 Lanthipeptides: EB42_RS00090_lanthipeptide NZ_KZ845958.1 Lanthipeptides: EB53_RS07695_lanthipeptide NZ_KZ845958.1 Lanthipeptides: EB53_RS07695_lanthipeptide NZ_LR607361.1 Lanthipeptides: FN738_RS03740_lanthipeptide NZ_LR607361.1 Lanthipeptides: FN738_RS03740_lanthipeptide NZ_LR607378.1 Lanthipeptides: FN751_RS00125_lanthipeptide NZ_LR607378.1 Lanthipeptides: FN751_RS00125_lanthipeptide NZ_LSFS01000007.1 Lanthipeptides: AW733_RS07745_lanthipeptide NZ_LSFS01000007.1 Lanthipeptides: AW733_RS07745_lanthipeptide NZ_NGMP01000002.1 Lanthipeptides: A5830_RS04680_lanthipeptide NZ_NGMP01000002.1 Lanthipeptides: A5830_RS04680_lanthipeptide NZ_NGMV01000001.1 Lanthipeptides: A5824_RS07985_lanthipeptide NZ_NGMV01000001.1 Lanthipeptides: A5824_RS07985_lanthipeptide
Lanthipeptides: PO853_RS06520_lanthipeptide
1
G T P A I F S A I S-A I T A V T V Q S P C P T S A C S K S C
30
G T P I I S A++ C P T S C+++C
1
G T P T I T I P I S I A V S G W I S D K T C P T S V C T R A C
31
41.9%
NZ_MLKL01000042.1:
Lanthipeptides: BKK45_RS27405_lanthipeptide
3
P A I F S A I S A I T A V T V Q S P C P T S A C S K S C
30
P A I A V+V+ C P T C+K S C
5
P E T T P A T P T I V A V S V K L-C P T G V C T K S C
31
41.7%
NZ_CP047645.1 and 5 others:
NZ_CP047645.1 Lanthipeptides: GSN02_RS17435_lanthipeptide NZ_NJRE01000008.1 Lanthipeptides: CE047_RS18550_lanthipeptide NZ_NJRE01000008.1 Lanthipeptides: CE047_RS18550_lanthipeptide NZ_VIOH01000001.1 Lanthipeptides: FLN47_RS03735_lanthipeptide NZ_VIOH01000001.1 Lanthipeptides: FLN47_RS03735_lanthipeptide
Lanthipeptides: GSN02_RS17435_lanthipeptide
1
G T P--A I F S A I S A I T A V T V Q S P--C P T S A C S K S C
30
G T P A I +A++ T S C P T S A C+ C
1
G T P V T A I I T A L T G T T F T V T L S A A S C P T S A C T N L C
34
41.7%
NZ_JALAUA010000003.1 and 1 other:
NZ_JALAUA010000003.1 Lanthipeptides: MOD32_RS04870_lanthipeptide
Lanthipeptides: MOD32_RS04870_lanthipeptide
1
G T P--A I F S A I S A I T A V T V Q S P--C P T S A C S K S C
30
G T P A I +A++ T S C P T S A C+ C
1
G T P V T A I L T A L T G T T F T V T L S A A S C P T S A C T N L C
34
40.0%
NZ_JAENHN010000066.1 and 1 other:
NZ_JAENHN010000066.1 Lanthipeptides: JHL18_RS24405_lanthipeptide
Lanthipeptides: JHL18_RS24405_lanthipeptide
1
G T P A I F S A I S A I T A V T V Q----S P C P T S A C S K S C
30
G T P A I + ++ I T T V + C T A C+ C
1
G T P A I I T I V T L I T K A T V S V A T V A V C E T G A C T S Y C
34
37.8%
NZ_PNGD01000001.1 and 1 other:
NZ_PNGD01000001.1 Lanthipeptides: CJ239_RS00165_lanthipeptide
Lanthipeptides: CJ239_RS00165_lanthipeptide
2
T P A I F S A I S A I T A V T V Q-----S P C P T S A C S K S C
30
T P I +A + V T C P T S C+K S C
2
T P T I I A A T I S F A G V T F T V T L N A G A C P T S G C T K S C
35
37.1%
NZ_CM000721.1 and 9 others:
NZ_CP015591.1 Lanthipeptides: A7A70_RS27555_lanthipeptide NZ_CP078085.1 Lanthipeptides: KU891_RS29360_lanthipeptide NZ_CP085411.1 Lanthipeptides: LIT28_RS29940_lanthipeptide NZ_CP085411.1 Lanthipeptides: LIT28_RS29935_lanthipeptide NZ_CP085411.1 Lanthipeptides: LIT28_RS29940_lanthipeptide NZ_CP085411.1 Lanthipeptides: LIT28_RS29935_lanthipeptide NZ_NUBO01000052.1 Lanthipeptides: CN575_RS29785_lanthipeptide NZ_QNUC01000031.1 Lanthipeptides: DN396_RS23040_lanthipeptide NZ_QNUC01000031.1 Lanthipeptides: DN396_RS23040_lanthipeptide
Lanthipeptides: BCERE0010_RS29355_lanthipeptide
2
T P A I F S A I S A I T A V T V Q S P C P T S A C S K S C
30
T P I A A+T A S C P T+ C+ C
11
T P T I I G A T I A V T A----S L C P T T K C T S R C
35
36.7%
NZ_CP051884.1 and 3 others:
NZ_CP051884.1 Lanthipeptides: HGK68_RS15130_lanthipeptide NZ_CP051884.1 Lanthipeptides: HGK68_RS15130_lanthipeptide NZ_CP051884.1 Lanthipeptides: HGK68_RS15130_lanthipeptide
Lanthipeptides: HGK68_RS15130_lanthipeptide
1
G T P A I F S A I S A I T A V T V Q S P C P T S A C S K S C
30
G T P + +S ++A + C P+S A C+++C
1
G T P T V V--L S I V S A W I S N N T C P S S A C T R A C
28
36.7%
NZ_CP061868.1 and 1 other:
NZ_CP061868.1 Lanthipeptides: IE339_RS06335_lanthipeptide
Lanthipeptides: IE339_RS06335_lanthipeptide
2
T P A I F S A I S A I T A V T V Q S P C P T S A C S K S C
30
T P I I+A+T + C P T++C+++C
2
T P T I--V I T A V T G Y I S T N T C P T T S C T R A C
28
J2M30_RS09860
Leader:
MKKGLFDQIAKEDMENILVEIDEHQEMAGF
Core:
N T W N T I S T S T C I A V S H F V G N D G K V C T Y T V E C V N N C R
Core with dehydrations:
N Dhb W N Dhb I Dha Dhb Dha Dhb Cys I A V Dha H F V G N D G K V Cys Dhb Y Dhb V E Cys V N N Cys R

#### antiSMASH-DB 4.0 matches for J2M30_RS09860

100.0%
NZ_JAGKQT010000007.1 and 3 others:
NZ_JAGKQT010000007.1 Lanthipeptides: J2M30_RS09860_lanthipeptide NZ_LVYL01000010.1 Lanthipeptides: A3863_RS05855_lanthipeptide NZ_LVYL01000010.1 Lanthipeptides: A3863_RS05855_lanthipeptide
Lanthipeptides: J2M30_RS09860_lanthipeptide
1
N T W N T I S T S T C I A V S H F V G N D G K V C T Y T V E C V N N C R
36
N T W N T I S T S T C I A V S H F V G N D G K V C T Y T V E C V N N C R
1
N T W N T I S T S T C I A V S H F V G N D G K V C T Y T V E C V N N C R
36
71.1%
NZ_CM000756.1 and 7 others:
NZ_CM000756.1 Lanthipeptides: BTHUR0011_RS34475_lanthipeptide NZ_CP031749.1 Lanthipeptides: DPQ26_RS30450_lanthipeptide NZ_CP031749.1 Lanthipeptides: DPQ26_RS30450_lanthipeptide NZ_CP036071.1 Lanthipeptides: EXW41_RS29770_lanthipeptide NZ_CP036071.1 Lanthipeptides: EXW41_RS29770_lanthipeptide NZ_WBPC01000036.1 Lanthipeptides: F8159_RS30260_lanthipeptide NZ_WBPC01000036.1 Lanthipeptides: F8159_RS30260_lanthipeptide
Lanthipeptides: BTHUR0011_RS34475_lanthipeptide
1
N T W N T I S T S T C I A V S H F V G N D G K V C T Y T V E C V N N C R
36
N T W N T +T S T I +S G N G K V C T Y T V E C V N N C R
2
N T W N T T A T S T S I I I S E T F G N K G K V C T Y T V E C V N N C R
37
56.8%
NZ_CP017953.1 and 27 others:
NZ_CP017953.1 Lanthipeptides: BAMY_RS16400_lanthipeptide NZ_CP021011.1 Lanthipeptides: B6257_RS06480_lanthipeptide NZ_CP021011.1 Lanthipeptides: B6257_RS06480_lanthipeptide NZ_CP033054.1 Lanthipeptides: D9777_RS18850_lanthipeptide NZ_CP033054.1 Lanthipeptides: D9777_RS18850_lanthipeptide NZ_CP041784.1 Lanthipeptides: FOV14_RS15900_lanthipeptide NZ_CP041784.1 Lanthipeptides: FOV14_RS15900_lanthipeptide NZ_CP047268.1 Lanthipeptides: GKS41_RS18615_lanthipeptide NZ_CP047268.1 Lanthipeptides: GKS41_RS18615_lanthipeptide NZ_CP048002.1 Lanthipeptides: GWK37_RS05705_lanthipeptide NZ_CP048002.1 Lanthipeptides: GWK37_RS05705_lanthipeptide NZ_CP072563.1 Lanthipeptides: J6600_RS15945_lanthipeptide NZ_CP072563.1 Lanthipeptides: J6600_RS15945_lanthipeptide NZ_CP097326.1 Lanthipeptides: M5J22_RS16190_lanthipeptide NZ_CP097326.1 Lanthipeptides: M5J22_RS16190_lanthipeptide NZ_CP097784.1 Lanthipeptides: MF619_RS16160_lanthipeptide NZ_CP097784.1 Lanthipeptides: MF619_RS16160_lanthipeptide NZ_CP116014.1 Lanthipeptides: PF996_RS17895_lanthipeptide NZ_CP116014.1 Lanthipeptides: PF996_RS17895_lanthipeptide NZ_JAAKXX010000011.1 Lanthipeptides: G6H00_RS11815_lanthipeptide NZ_JAAKXX010000011.1 Lanthipeptides: G6H00_RS11815_lanthipeptide NZ_JAANHO010000006.1 Lanthipeptides: G9F75_RS12550_lanthipeptide NZ_JAANHO010000006.1 Lanthipeptides: G9F75_RS12550_lanthipeptide NZ_JAIONG010000001.1 Lanthipeptides: K8B35_RS01375_lanthipeptide NZ_JAIONG010000001.1 Lanthipeptides: K8B35_RS01375_lanthipeptide NZ_LMAG01000012.1 Lanthipeptides: ASQ47_RS06825_lanthipeptide NZ_LMAG01000012.1 Lanthipeptides: ASQ47_RS06825_lanthipeptide
Lanthipeptides: BAMY_RS16400_lanthipeptide
1
N T W N T I S T S T C-I A V S H F V G N D G K V C T Y T V E C V N N C
35
N T W N T +T S I V S +G N G K V C T T E C C
2
N T W N T T T T S L G G I L V S E V L G N K G K V C T G T K E C Q G T C
37
with 90 more sequence matches
Only the first 10 are displayed here.
56.8%
NZ_CP047645.1 and 7 others:
NZ_CP047645.1 Lanthipeptides: GSN02_RS17445_lanthipeptide NZ_JALAUA010000003.1 Lanthipeptides: MOD32_RS04860_lanthipeptide NZ_JALAUA010000003.1 Lanthipeptides: MOD32_RS04860_lanthipeptide NZ_NJRE01000008.1 Lanthipeptides: CE047_RS18560_lanthipeptide NZ_NJRE01000008.1 Lanthipeptides: CE047_RS18560_lanthipeptide NZ_VIOH01000001.1 Lanthipeptides: FLN47_RS03725_lanthipeptide NZ_VIOH01000001.1 Lanthipeptides: FLN47_RS03725_lanthipeptide
Lanthipeptides: GSN02_RS17445_lanthipeptide
1
N T W N T I S T S T-C I A V S H F V G N D G K V C T Y T V E C V N N C
35
N T W N T +T S I V S G N G K V C T T E C C
2
N T W N T T T T S V G T I L V S E V F G N K G K V C T G T K E C Q G T C
37
50.0%
NZ_JAQFWW010000002.1 and 1 other:
NZ_JAQFWW010000002.1 Lanthipeptides: PDT38_RS11330_lanthipeptide
Lanthipeptides: PDT38_RS11330_lanthipeptide
2
T W N T I S T S-T C I A V S H F V G N D G K V C T Y T V E C V N N C R
36
+W T+ T+ +C+A S +G+ G+V C T T V E C N N C R
2
S W G T L L T T L S C L A A S I M I G D K G Q V C T G T V E C Q N N C R
37
48.7%
NZ_JALGRP010000007.1 and 1 other:
NZ_JALGRP010000007.1 Lanthipeptides: MT347_RS12955_lanthipeptide
Lanthipeptides: MT347_RS12955_lanthipeptide
5
T I S T S T C I A V S H F V G N D G K V C T Y T V E C V N N C
35
T I++ T C V S G N+G+V C T T V E C N N C
8
T I T S L T C Y G V S W V A G N N G Q V C T A T V E C Q N N C
38
48.6%
NZ_VTZW01000015.1 and 1 other:
NZ_VTZW01000015.1 Lanthipeptides: FZ103_RS15850_lanthipeptide
Lanthipeptides: FZ103_RS15850_lanthipeptide
4
N T I S T S T----C I A V S H F V G N D G K V C T Y T V E C V N N C
35
N+I S +T C+A S V G N+G C T T V E C + C
3
N S I S I A T A C V S C L A-S W A V G N E G W A C T V T V E C Q D G C
37
47.4%
NZ_LT575476.1 and 1 other:
NZ_LT575476.1 Lanthipeptides: BN6628_RS02285_lanthipeptide
Lanthipeptides: BN6628_RS02285_lanthipeptide
2
T W N T I S T S-T C I A V S H F V G N D G K V C T Y T V E C V N N C R
36
+W T+ T+ C+ S+ +G+ G+V C T T V E C+N N C R
2
S W G T V L T T L A C L G A S Y A L G D K G Q V C T A T V E C I N N C R
37
47.2%
NC_017299.1 and 1 other:
NC_017299.1 Lanthipeptides: H04402_RS03105_lanthipeptide
Lanthipeptides: H04402_RS03105_lanthipeptide
12
I A V S H F V G N D G K V C T Y T V E C V N N C
35
I +S ++G N D G K V C T+T V E C N N C
9
I T L S V Y M G N D G K V C T W T V E C Q N N C
32
47.2%
NZ_CP009280.1 and 1 other:
NZ_CP009280.1 Lanthipeptides: P40081_RS01820_lanthipeptide
Lanthipeptides: P40081_RS01820_lanthipeptide
4
N T I S T S T C I A V S H F V G N D G K V C T Y T V E C V N N C
35
N T++T S T I +S +G N D G V C T++ E C+ +C
4
N T L T T S T S I F I S R G L G N D G W V C T W S K E C M P S C
35
47.2%
NZ_CP009288.1 and 3 others:
NZ_CP009288.1 Lanthipeptides: PDUR_RS25150_lanthipeptide NZ_CP076607.1 Lanthipeptides: KP014_RS01580_lanthipeptide NZ_CP076607.1 Lanthipeptides: KP014_RS01580_lanthipeptide
Lanthipeptides: PDUR_RS25150_lanthipeptide
4
N T I S T S T C I A V S H F V G N D G K V C T Y T V E C V N N C
35
N T++T S T I +S +G N+G V C T T E C+ +C
4
N T L T T S T S I L I S M T L G N N G W V C T A T K E C M P S C
35
45.9%
NZ_QKTG01000020.1 and 1 other:
NZ_QKTG01000020.1 Lanthipeptides: DEI99_RS16920_lanthipeptide
Lanthipeptides: DEI99_RS16920_lanthipeptide
5
T I S T S T C I A V S H F V G N D G K V C T Y T V E C V N N C R
36
T++T +C V S +G N D G C T T V E C +N C+
6
T V T T L S C Y G V S W A L G N D G N F C T A T V E C Q S N C K
37
45.0%
NZ_JALIRS010000003.1 and 3 others:
NZ_JALIRS010000003.1 Lanthipeptides: MOK21_RS07255_lanthipeptide NZ_JALNLQ010000002.1 Lanthipeptides: MWJ95_RS06810_lanthipeptide NZ_JALNLQ010000002.1 Lanthipeptides: MWJ95_RS06810_lanthipeptide
Lanthipeptides: MOK21_RS07255_lanthipeptide
4
N T I S T S-T C I A V S H F V G N D G K V C T Y T V E C V N N C
35
T I T S C A S+ +G N G V C T T V E C C
7
E T I L T S L A C A A A S Y I L G N P G H V C T L T V E C Q K K C
39

#### MIBiG 4.0 matches for J2M30_RS09860

33.3%
BGC0002110.3 (QKV49893.1):
Lanthipeptide: birimositide
8
T S T C I A V S H F V G N D G K V C T Y T V E C V N N C
35
T+ ++S+ +G N+G C T T E C N C
2
T T N T F S L S N A L G N N G G W C T L T K E C Q P N C
29
30.6%
BGC0000517.4 (BAB04173.1):
Lanthipeptide: haloduracin β or haloduracin α
14
V S H F V G N D G K V C T Y T V E C V N N C
35
+S +G N G C T T V E C+ +C
6
I S C R L G N K G A Y C T L T V E C M P S C
27
15.4%
BGC0001229.4 (SBI_06990):
Lanthipeptide: SBI-06990 A1 or SBI-06989 A2
25
C T Y T V E C V N N C
35
C T + E C N C
28
C T L S K E C Q P N C
38
with 1 more sequence matches
7.8%
BGC0002120.3 (NQE92413.1):
Lanthipeptide: nocathioamide A
4
N T I S T S T C I A
13
+T+S+ C A
41
H T L S S L P C C A
50
J2M30_RS09870
Leader:
MKFANKMKAA
Core:
L M N K V A N S I M L I A T F G A I N S C T F L F H E D E V P E E L Q K D N P F L D K S G R D E G L
Core with dehydrations:
L M N K V A N Dha I M L I A Dhb F G A I N Dha Cys Dhb F L F H E D E V P E E L Q K D N P F L D K Dha G R D E G L

#### antiSMASH-DB 4.0 matches for J2M30_RS09870

100.0%
NZ_JAGKQT010000007.1 and 1 other:
NZ_JAGKQT010000007.1 Lanthipeptides: J2M30_RS09870_lanthipeptide
Lanthipeptides: J2M30_RS09870_lanthipeptide
1
L M N K V A N S I M L I A T F G A I N S C T F L F H E D E V P E E L Q K D N P F L D K S G R D E G L
50
L M N K V A N S I M L I A T F G A I N S C T F L F H E D E V P E E L Q K D N P F L D K S G R D E G L
1
L M N K V A N S I M L I A T F G A I N S C T F L F H E D E V P E E L Q K D N P F L D K S G R D E G L
50
56.0%
NZ_LVYL01000010.1 and 1 other:
NZ_LVYL01000010.1 Lanthipeptides: A3863_RS05845_lanthipeptide
Lanthipeptides: A3863_RS05845_lanthipeptide
18
I N S C T F L F H E D E V P E E L Q K D N P F L D K S G R D E G L
50
I N S C T F L F H E D E V P E E L Q K+N P F L K+G E G L
1
I N S C T F L F H E D E V P E E L Q K N N P F L Y K N G G K E G L
33
17.9%
NZ_CP117772.1:
Lanthipeptides: allorf_0438568_0438768_lanthipeptide
9
I M L I A T F G A I N S C T F L F H E D E V P E E L Q K D N P
39
+ L+ G I+S + F H+ E K+N P
16
L A L L V I A G F I S S S L W F F H K H I E H E T C S K N N P
46
with 6 more sequence matches
16.0%
NZ_MIFM01000001.1 and 1 other:
NZ_NINI01000009.1 Lanthipeptides: CEV12_RS07225_lanthipeptide
Lanthipeptides: BHL22_RS00375_lanthipeptide
15
F G A I N S C T F L F H E D E V P E E L Q K D N
38
F G++ C E+E+P E+L+ ++
1
F G S L Y M C W G F L D E E E I P E K L K G N D
24
14.0%
NZ_JAQEYW010000015.1:
Lanthipeptides: PG422_RS12370_lanthipeptide
17
A I N S-C T F L F H E D E V P E E L Q K
36
A+N S C ++H+ ++P+E+++
6
A V N S R C V C I Y H Q P K M P K E M K Q
26
14.0%
NZ_LR134483.1 and 1 other:
NZ_LR134483.1 Lanthipeptides: EL241_RS01765_lanthipeptide
Lanthipeptides: EL241_RS01765_lanthipeptide
18
I N S C T F L F H E D-E V P E E L
34
+ C F L ++ E+P+E L
3
V R Q C C F L L S D E I E I P D E L
20
12.0%
NZ_FNFB01000016.1:
Lanthipeptides: allorf_081491_081622_lanthipeptide
34
L Q K D N P F L D K S G R D E
48
+ +D+P F L + R D+
4
V A Q D S P F L T F A A R D D
18
12.0%
NZ_JANYMP010000013.1:
Lanthipeptides: allorf_203043_203156_lanthipeptide
19
N S C T F L F
25
N S C T F+F
8
N S C T F I F
14
8.0%
NZ_CP084014.1 and 1 other:
NZ_CP094679.1 Lanthipeptides: K5I24_RS13140_lanthipeptide
Lanthipeptides: LCQ72_RS00060_lanthipeptide
19
N S C T F L F H E D E V P E E L Q K
36
+ C ++H+ ++P+E+++
2
S R C V C I Y H Q P K M P K E M K Q
19
allorf_071326_071475
Leader:
MALYSTSFIVGIVLASSSLMMFQASLSFM
Core:
I K Y G N S F V N F I I G G E E T Q K C
Core with dehydrations:
I K Y G N Dha F V N F I I G G E E Dhb Q K Cys

#### antiSMASH-DB 4.0 matches for allorf_071326_071475

100.0%
NZ_JAGKQT010000007.1:
Lanthipeptides: allorf_071326_071475_lanthipeptide
1
I K Y G N S F V N F I I G G E E T Q K C
20
I K Y G N S F V N F I I G G E E T Q K C
1
I K Y G N S F V N F I I G G E E T Q K C
20

#### Lanthipeptide(s) for J2M30_RS09850

J2M30_RS09845
Leader:
MKNMKELEKVTGLISEEELDQDLSEVNGA
Core:
G T P A I F S A I S A I T A V T V Q S P C P T S A C S K S C
Core with dehydrations:
G Dhb P A I F Dha A I Dha A I Dhb A V Dhb V Q Dha P Cys P Dhb Dha A Cys Dha K Dha Cys

#### antiSMASH-DB 4.0 matches for J2M30_RS09845

100.0%
NZ_JAGKQT010000007.1 and 3 others:
NZ_JAGKQT010000007.1 Lanthipeptides: J2M30_RS09845_lanthipeptide NZ_LVYL01000010.1 Lanthipeptides: A3863_RS05870_lanthipeptide NZ_LVYL01000010.1 Lanthipeptides: A3863_RS05870_lanthipeptide
Lanthipeptides: J2M30_RS09845_lanthipeptide
1
G T P A I F S A I S A I T A V T V Q S P C P T S A C S K S C
30
G T P A I F S A I S A I T A V T V Q S P C P T S A C S K S C
1
G T P A I F S A I S A I T A V T V Q S P C P T S A C S K S C
30
70.3%
NZ_CM000756.1 and 17 others:
NZ_CM000756.1 Lanthipeptides: BTHUR0011_RS14760_lanthipeptide NZ_CM000756.1 Lanthipeptides: BTHUR0011_RS14765_lanthipeptide NZ_CM000756.1 Lanthipeptides: BTHUR0011_RS14760_lanthipeptide NZ_CP031749.1 Lanthipeptides: DPQ26_RS29740_lanthipeptide NZ_CP031749.1 Lanthipeptides: DPQ26_RS29735_lanthipeptide NZ_CP031749.1 Lanthipeptides: DPQ26_RS29730_lanthipeptide NZ_CP031749.1 Lanthipeptides: DPQ26_RS29740_lanthipeptide NZ_CP031749.1 Lanthipeptides: DPQ26_RS29735_lanthipeptide NZ_CP031749.1 Lanthipeptides: DPQ26_RS29730_lanthipeptide NZ_CP036071.1 Lanthipeptides: EXW41_RS26900_lanthipeptide NZ_CP036071.1 Lanthipeptides: EXW41_RS26895_lanthipeptide NZ_CP036071.1 Lanthipeptides: EXW41_RS26900_lanthipeptide NZ_CP036071.1 Lanthipeptides: EXW41_RS26895_lanthipeptide NZ_WBPC01000036.1 Lanthipeptides: F8159_RS22545_lanthipeptide NZ_WBPC01000036.1 Lanthipeptides: F8159_RS22540_lanthipeptide NZ_WBPC01000036.1 Lanthipeptides: F8159_RS22545_lanthipeptide NZ_WBPC01000036.1 Lanthipeptides: F8159_RS22540_lanthipeptide
Lanthipeptides: BTHUR0011_RS14765_lanthipeptide
1
G T P A I F S A I S A I T A V T V Q S P C P T S A C S K S C
30
G T P A I +A I S A+T A V T Q S P C P T S A C S K S C
6
G T P A I V T A I S A V T A V T A Q S P C P T S A C S K S C
35
43.3%
NZ_PCGR01000003.1 and 1 other:
NZ_PCGR01000003.1 Lanthipeptides: CQS04_RS09625_lanthipeptide
Lanthipeptides: CQS04_RS09625_lanthipeptide
2
T P A I F S A I S A I T A V T V Q S P C P T S A C S K S C
30
T P I I+A I T + C P T+A C+++C
2
T P T I V--I T A I T G Y I S A N S C P T T A C T R A C
28
with 60 more sequence matches
Only the first 10 are displayed here.
42.1%
NC_006322.1 and 7 others:
NC_006322.1 Lanthipeptides: BLI_RS20290_lanthipeptide NZ_CP033218.1 Lanthipeptides: D9Y32_RS07810_lanthipeptide NZ_CP033218.1 Lanthipeptides: D9Y32_RS07810_lanthipeptide NZ_LQYL01000021.1 Lanthipeptides: B4090_RS08830_lanthipeptide NZ_LQYL01000021.1 Lanthipeptides: B4090_RS08830_lanthipeptide NZ_NIMP01000036.1 Lanthipeptides: CHCC14566_RS11870_lanthipeptide NZ_NIMP01000036.1 Lanthipeptides: CHCC14566_RS11870_lanthipeptide
Lanthipeptides: BLI_RS20290_lanthipeptide
2
T P A I F S A I S A I T A-V T V Q-S P C P T S A C S K S C
30
T P A S+ + I T A V T V S C P T+ C+ C
8
T P A T T S S W T C I T A G V T V S A S L C P T T K C T S R C
38
41.9%
NZ_AP026714.1 and 21 others:
NZ_AP026714.1 Lanthipeptides: PO853_RS06520_lanthipeptide NZ_CP028724.1 Lanthipeptides: C7I31_RS11270_lanthipeptide NZ_CP028724.1 Lanthipeptides: C7I31_RS11270_lanthipeptide NZ_CP092907.1 Lanthipeptides: MK744_RS03990_lanthipeptide NZ_CP092907.1 Lanthipeptides: MK744_RS03990_lanthipeptide NZ_KB944759.1 Lanthipeptides: WOA_RS09815_lanthipeptide NZ_KB944759.1 Lanthipeptides: WOA_RS09815_lanthipeptide NZ_KZ845892.1 Lanthipeptides: EB42_RS00090_lanthipeptide NZ_KZ845892.1 Lanthipeptides: EB42_RS00090_lanthipeptide NZ_KZ845958.1 Lanthipeptides: EB53_RS07695_lanthipeptide NZ_KZ845958.1 Lanthipeptides: EB53_RS07695_lanthipeptide NZ_LR607361.1 Lanthipeptides: FN738_RS03740_lanthipeptide NZ_LR607361.1 Lanthipeptides: FN738_RS03740_lanthipeptide NZ_LR607378.1 Lanthipeptides: FN751_RS00125_lanthipeptide NZ_LR607378.1 Lanthipeptides: FN751_RS00125_lanthipeptide NZ_LSFS01000007.1 Lanthipeptides: AW733_RS07745_lanthipeptide NZ_LSFS01000007.1 Lanthipeptides: AW733_RS07745_lanthipeptide NZ_NGMP01000002.1 Lanthipeptides: A5830_RS04680_lanthipeptide NZ_NGMP01000002.1 Lanthipeptides: A5830_RS04680_lanthipeptide NZ_NGMV01000001.1 Lanthipeptides: A5824_RS07985_lanthipeptide NZ_NGMV01000001.1 Lanthipeptides: A5824_RS07985_lanthipeptide
Lanthipeptides: PO853_RS06520_lanthipeptide
1
G T P A I F S A I S-A I T A V T V Q S P C P T S A C S K S C
30
G T P I I S A++ C P T S C+++C
1
G T P T I T I P I S I A V S G W I S D K T C P T S V C T R A C
31
41.9%
NZ_MLKL01000042.1:
Lanthipeptides: BKK45_RS27405_lanthipeptide
3
P A I F S A I S A I T A V T V Q S P C P T S A C S K S C
30
P A I A V+V+ C P T C+K S C
5
P E T T P A T P T I V A V S V K L-C P T G V C T K S C
31
41.7%
NZ_CP047645.1 and 5 others:
NZ_CP047645.1 Lanthipeptides: GSN02_RS17435_lanthipeptide NZ_NJRE01000008.1 Lanthipeptides: CE047_RS18550_lanthipeptide NZ_NJRE01000008.1 Lanthipeptides: CE047_RS18550_lanthipeptide NZ_VIOH01000001.1 Lanthipeptides: FLN47_RS03735_lanthipeptide NZ_VIOH01000001.1 Lanthipeptides: FLN47_RS03735_lanthipeptide
Lanthipeptides: GSN02_RS17435_lanthipeptide
1
G T P--A I F S A I S A I T A V T V Q S P--C P T S A C S K S C
30
G T P A I +A++ T S C P T S A C+ C
1
G T P V T A I I T A L T G T T F T V T L S A A S C P T S A C T N L C
34
41.7%
NZ_JALAUA010000003.1 and 1 other:
NZ_JALAUA010000003.1 Lanthipeptides: MOD32_RS04870_lanthipeptide
Lanthipeptides: MOD32_RS04870_lanthipeptide
1
G T P--A I F S A I S A I T A V T V Q S P--C P T S A C S K S C
30
G T P A I +A++ T S C P T S A C+ C
1
G T P V T A I L T A L T G T T F T V T L S A A S C P T S A C T N L C
34
40.0%
NZ_JAENHN010000066.1 and 1 other:
NZ_JAENHN010000066.1 Lanthipeptides: JHL18_RS24405_lanthipeptide
Lanthipeptides: JHL18_RS24405_lanthipeptide
1
G T P A I F S A I S A I T A V T V Q----S P C P T S A C S K S C
30
G T P A I + ++ I T T V + C T A C+ C
1
G T P A I I T I V T L I T K A T V S V A T V A V C E T G A C T S Y C
34
37.8%
NZ_PNGD01000001.1 and 1 other:
NZ_PNGD01000001.1 Lanthipeptides: CJ239_RS00165_lanthipeptide
Lanthipeptides: CJ239_RS00165_lanthipeptide
2
T P A I F S A I S A I T A V T V Q-----S P C P T S A C S K S C
30
T P I +A + V T C P T S C+K S C
2
T P T I I A A T I S F A G V T F T V T L N A G A C P T S G C T K S C
35
37.1%
NZ_CM000721.1 and 9 others:
NZ_CP015591.1 Lanthipeptides: A7A70_RS27555_lanthipeptide NZ_CP078085.1 Lanthipeptides: KU891_RS29360_lanthipeptide NZ_CP085411.1 Lanthipeptides: LIT28_RS29940_lanthipeptide NZ_CP085411.1 Lanthipeptides: LIT28_RS29935_lanthipeptide NZ_CP085411.1 Lanthipeptides: LIT28_RS29940_lanthipeptide NZ_CP085411.1 Lanthipeptides: LIT28_RS29935_lanthipeptide NZ_NUBO01000052.1 Lanthipeptides: CN575_RS29785_lanthipeptide NZ_QNUC01000031.1 Lanthipeptides: DN396_RS23040_lanthipeptide NZ_QNUC01000031.1 Lanthipeptides: DN396_RS23040_lanthipeptide
Lanthipeptides: BCERE0010_RS29355_lanthipeptide
2
T P A I F S A I S A I T A V T V Q S P C P T S A C S K S C
30
T P I A A+T A S C P T+ C+ C
11
T P T I I G A T I A V T A----S L C P T T K C T S R C
35
36.7%
NZ_CP051884.1 and 3 others:
NZ_CP051884.1 Lanthipeptides: HGK68_RS15130_lanthipeptide NZ_CP051884.1 Lanthipeptides: HGK68_RS15130_lanthipeptide NZ_CP051884.1 Lanthipeptides: HGK68_RS15130_lanthipeptide
Lanthipeptides: HGK68_RS15130_lanthipeptide
1
G T P A I F S A I S A I T A V T V Q S P C P T S A C S K S C
30
G T P + +S ++A + C P+S A C+++C
1
G T P T V V--L S I V S A W I S N N T C P S S A C T R A C
28
36.7%
NZ_CP061868.1 and 1 other:
NZ_CP061868.1 Lanthipeptides: IE339_RS06335_lanthipeptide
Lanthipeptides: IE339_RS06335_lanthipeptide
2
T P A I F S A I S A I T A V T V Q S P C P T S A C S K S C
30
T P I I+A+T + C P T++C+++C
2
T P T I--V I T A V T G Y I S T N T C P T T S C T R A C
28
J2M30_RS09860
Leader:
MKKGLFDQIAKEDMENILVEIDEHQEMAGF
Core:
N T W N T I S T S T C I A V S H F V G N D G K V C T Y T V E C V N N C R
Core with dehydrations:
N Dhb W N Dhb I Dha Dhb Dha Dhb Cys I A V Dha H F V G N D G K V Cys Dhb Y Dhb V E Cys V N N Cys R

#### antiSMASH-DB 4.0 matches for J2M30_RS09860

100.0%
NZ_JAGKQT010000007.1 and 3 others:
NZ_JAGKQT010000007.1 Lanthipeptides: J2M30_RS09860_lanthipeptide NZ_LVYL01000010.1 Lanthipeptides: A3863_RS05855_lanthipeptide NZ_LVYL01000010.1 Lanthipeptides: A3863_RS05855_lanthipeptide
Lanthipeptides: J2M30_RS09860_lanthipeptide
1
N T W N T I S T S T C I A V S H F V G N D G K V C T Y T V E C V N N C R
36
N T W N T I S T S T C I A V S H F V G N D G K V C T Y T V E C V N N C R
1
N T W N T I S T S T C I A V S H F V G N D G K V C T Y T V E C V N N C R
36
71.1%
NZ_CM000756.1 and 7 others:
NZ_CM000756.1 Lanthipeptides: BTHUR0011_RS34475_lanthipeptide NZ_CP031749.1 Lanthipeptides: DPQ26_RS30450_lanthipeptide NZ_CP031749.1 Lanthipeptides: DPQ26_RS30450_lanthipeptide NZ_CP036071.1 Lanthipeptides: EXW41_RS29770_lanthipeptide NZ_CP036071.1 Lanthipeptides: EXW41_RS29770_lanthipeptide NZ_WBPC01000036.1 Lanthipeptides: F8159_RS30260_lanthipeptide NZ_WBPC01000036.1 Lanthipeptides: F8159_RS30260_lanthipeptide
Lanthipeptides: BTHUR0011_RS34475_lanthipeptide
1
N T W N T I S T S T C I A V S H F V G N D G K V C T Y T V E C V N N C R
36
N T W N T +T S T I +S G N G K V C T Y T V E C V N N C R
2
N T W N T T A T S T S I I I S E T F G N K G K V C T Y T V E C V N N C R
37
56.8%
NZ_CP017953.1 and 27 others:
NZ_CP017953.1 Lanthipeptides: BAMY_RS16400_lanthipeptide NZ_CP021011.1 Lanthipeptides: B6257_RS06480_lanthipeptide NZ_CP021011.1 Lanthipeptides: B6257_RS06480_lanthipeptide NZ_CP033054.1 Lanthipeptides: D9777_RS18850_lanthipeptide NZ_CP033054.1 Lanthipeptides: D9777_RS18850_lanthipeptide NZ_CP041784.1 Lanthipeptides: FOV14_RS15900_lanthipeptide NZ_CP041784.1 Lanthipeptides: FOV14_RS15900_lanthipeptide NZ_CP047268.1 Lanthipeptides: GKS41_RS18615_lanthipeptide NZ_CP047268.1 Lanthipeptides: GKS41_RS18615_lanthipeptide NZ_CP048002.1 Lanthipeptides: GWK37_RS05705_lanthipeptide NZ_CP048002.1 Lanthipeptides: GWK37_RS05705_lanthipeptide NZ_CP072563.1 Lanthipeptides: J6600_RS15945_lanthipeptide NZ_CP072563.1 Lanthipeptides: J6600_RS15945_lanthipeptide NZ_CP097326.1 Lanthipeptides: M5J22_RS16190_lanthipeptide NZ_CP097326.1 Lanthipeptides: M5J22_RS16190_lanthipeptide NZ_CP097784.1 Lanthipeptides: MF619_RS16160_lanthipeptide NZ_CP097784.1 Lanthipeptides: MF619_RS16160_lanthipeptide NZ_CP116014.1 Lanthipeptides: PF996_RS17895_lanthipeptide NZ_CP116014.1 Lanthipeptides: PF996_RS17895_lanthipeptide NZ_JAAKXX010000011.1 Lanthipeptides: G6H00_RS11815_lanthipeptide NZ_JAAKXX010000011.1 Lanthipeptides: G6H00_RS11815_lanthipeptide NZ_JAANHO010000006.1 Lanthipeptides: G9F75_RS12550_lanthipeptide NZ_JAANHO010000006.1 Lanthipeptides: G9F75_RS12550_lanthipeptide NZ_JAIONG010000001.1 Lanthipeptides: K8B35_RS01375_lanthipeptide NZ_JAIONG010000001.1 Lanthipeptides: K8B35_RS01375_lanthipeptide NZ_LMAG01000012.1 Lanthipeptides: ASQ47_RS06825_lanthipeptide NZ_LMAG01000012.1 Lanthipeptides: ASQ47_RS06825_lanthipeptide
Lanthipeptides: BAMY_RS16400_lanthipeptide
1
N T W N T I S T S T C-I A V S H F V G N D G K V C T Y T V E C V N N C
35
N T W N T +T S I V S +G N G K V C T T E C C
2
N T W N T T T T S L G G I L V S E V L G N K G K V C T G T K E C Q G T C
37
with 90 more sequence matches
Only the first 10 are displayed here.
56.8%
NZ_CP047645.1 and 7 others:
NZ_CP047645.1 Lanthipeptides: GSN02_RS17445_lanthipeptide NZ_JALAUA010000003.1 Lanthipeptides: MOD32_RS04860_lanthipeptide NZ_JALAUA010000003.1 Lanthipeptides: MOD32_RS04860_lanthipeptide NZ_NJRE01000008.1 Lanthipeptides: CE047_RS18560_lanthipeptide NZ_NJRE01000008.1 Lanthipeptides: CE047_RS18560_lanthipeptide NZ_VIOH01000001.1 Lanthipeptides: FLN47_RS03725_lanthipeptide NZ_VIOH01000001.1 Lanthipeptides: FLN47_RS03725_lanthipeptide
Lanthipeptides: GSN02_RS17445_lanthipeptide
1
N T W N T I S T S T-C I A V S H F V G N D G K V C T Y T V E C V N N C
35
N T W N T +T S I V S G N G K V C T T E C C
2
N T W N T T T T S V G T I L V S E V F G N K G K V C T G T K E C Q G T C
37
50.0%
NZ_JAQFWW010000002.1 and 1 other:
NZ_JAQFWW010000002.1 Lanthipeptides: PDT38_RS11330_lanthipeptide
Lanthipeptides: PDT38_RS11330_lanthipeptide
2
T W N T I S T S-T C I A V S H F V G N D G K V C T Y T V E C V N N C R
36
+W T+ T+ +C+A S +G+ G+V C T T V E C N N C R
2
S W G T L L T T L S C L A A S I M I G D K G Q V C T G T V E C Q N N C R
37
48.7%
NZ_JALGRP010000007.1 and 1 other:
NZ_JALGRP010000007.1 Lanthipeptides: MT347_RS12955_lanthipeptide
Lanthipeptides: MT347_RS12955_lanthipeptide
5
T I S T S T C I A V S H F V G N D G K V C T Y T V E C V N N C
35
T I++ T C V S G N+G+V C T T V E C N N C
8
T I T S L T C Y G V S W V A G N N G Q V C T A T V E C Q N N C
38
48.6%
NZ_VTZW01000015.1 and 1 other:
NZ_VTZW01000015.1 Lanthipeptides: FZ103_RS15850_lanthipeptide
Lanthipeptides: FZ103_RS15850_lanthipeptide
4
N T I S T S T----C I A V S H F V G N D G K V C T Y T V E C V N N C
35
N+I S +T C+A S V G N+G C T T V E C + C
3
N S I S I A T A C V S C L A-S W A V G N E G W A C T V T V E C Q D G C
37
47.4%
NZ_LT575476.1 and 1 other:
NZ_LT575476.1 Lanthipeptides: BN6628_RS02285_lanthipeptide
Lanthipeptides: BN6628_RS02285_lanthipeptide
2
T W N T I S T S-T C I A V S H F V G N D G K V C T Y T V E C V N N C R
36
+W T+ T+ C+ S+ +G+ G+V C T T V E C+N N C R
2
S W G T V L T T L A C L G A S Y A L G D K G Q V C T A T V E C I N N C R
37
47.2%
NC_017299.1 and 1 other:
NC_017299.1 Lanthipeptides: H04402_RS03105_lanthipeptide
Lanthipeptides: H04402_RS03105_lanthipeptide
12
I A V S H F V G N D G K V C T Y T V E C V N N C
35
I +S ++G N D G K V C T+T V E C N N C
9
I T L S V Y M G N D G K V C T W T V E C Q N N C
32
47.2%
NZ_CP009280.1 and 1 other:
NZ_CP009280.1 Lanthipeptides: P40081_RS01820_lanthipeptide
Lanthipeptides: P40081_RS01820_lanthipeptide
4
N T I S T S T C I A V S H F V G N D G K V C T Y T V E C V N N C
35
N T++T S T I +S +G N D G V C T++ E C+ +C
4
N T L T T S T S I F I S R G L G N D G W V C T W S K E C M P S C
35
47.2%
NZ_CP009288.1 and 3 others:
NZ_CP009288.1 Lanthipeptides: PDUR_RS25150_lanthipeptide NZ_CP076607.1 Lanthipeptides: KP014_RS01580_lanthipeptide NZ_CP076607.1 Lanthipeptides: KP014_RS01580_lanthipeptide
Lanthipeptides: PDUR_RS25150_lanthipeptide
4
N T I S T S T C I A V S H F V G N D G K V C T Y T V E C V N N C
35
N T++T S T I +S +G N+G V C T T E C+ +C
4
N T L T T S T S I L I S M T L G N N G W V C T A T K E C M P S C
35
45.9%
NZ_QKTG01000020.1 and 1 other:
NZ_QKTG01000020.1 Lanthipeptides: DEI99_RS16920_lanthipeptide
Lanthipeptides: DEI99_RS16920_lanthipeptide
5
T I S T S T C I A V S H F V G N D G K V C T Y T V E C V N N C R
36
T++T +C V S +G N D G C T T V E C +N C+
6
T V T T L S C Y G V S W A L G N D G N F C T A T V E C Q S N C K
37
45.0%
NZ_JALIRS010000003.1 and 3 others:
NZ_JALIRS010000003.1 Lanthipeptides: MOK21_RS07255_lanthipeptide NZ_JALNLQ010000002.1 Lanthipeptides: MWJ95_RS06810_lanthipeptide NZ_JALNLQ010000002.1 Lanthipeptides: MWJ95_RS06810_lanthipeptide
Lanthipeptides: MOK21_RS07255_lanthipeptide
4
N T I S T S-T C I A V S H F V G N D G K V C T Y T V E C V N N C
35
T I T S C A S+ +G N G V C T T V E C C
7
E T I L T S L A C A A A S Y I L G N P G H V C T L T V E C Q K K C
39

#### MIBiG 4.0 matches for J2M30_RS09860

33.3%
BGC0002110.3 (QKV49893.1):
Lanthipeptide: birimositide
8
T S T C I A V S H F V G N D G K V C T Y T V E C V N N C
35
T+ ++S+ +G N+G C T T E C N C
2
T T N T F S L S N A L G N N G G W C T L T K E C Q P N C
29
30.6%
BGC0000517.4 (BAB04173.1):
Lanthipeptide: haloduracin β or haloduracin α
14
V S H F V G N D G K V C T Y T V E C V N N C
35
+S +G N G C T T V E C+ +C
6
I S C R L G N K G A Y C T L T V E C M P S C
27
15.4%
BGC0001229.4 (SBI_06990):
Lanthipeptide: SBI-06990 A1 or SBI-06989 A2
25
C T Y T V E C V N N C
35
C T + E C N C
28
C T L S K E C Q P N C
38
with 1 more sequence matches
7.8%
BGC0002120.3 (NQE92413.1):
Lanthipeptide: nocathioamide A
4
N T I S T S T C I A
13
+T+S+ C A
41
H T L S S L P C C A
50
J2M30_RS09870
Leader:
MKFANKMKAA
Core:
L M N K V A N S I M L I A T F G A I N S C T F L F H E D E V P E E L Q K D N P F L D K S G R D E G L
Core with dehydrations:
L M N K V A N Dha I M L I A Dhb F G A I N Dha Cys Dhb F L F H E D E V P E E L Q K D N P F L D K Dha G R D E G L

#### antiSMASH-DB 4.0 matches for J2M30_RS09870

100.0%
NZ_JAGKQT010000007.1 and 1 other:
NZ_JAGKQT010000007.1 Lanthipeptides: J2M30_RS09870_lanthipeptide
Lanthipeptides: J2M30_RS09870_lanthipeptide
1
L M N K V A N S I M L I A T F G A I N S C T F L F H E D E V P E E L Q K D N P F L D K S G R D E G L
50
L M N K V A N S I M L I A T F G A I N S C T F L F H E D E V P E E L Q K D N P F L D K S G R D E G L
1
L M N K V A N S I M L I A T F G A I N S C T F L F H E D E V P E E L Q K D N P F L D K S G R D E G L
50
56.0%
NZ_LVYL01000010.1 and 1 other:
NZ_LVYL01000010.1 Lanthipeptides: A3863_RS05845_lanthipeptide
Lanthipeptides: A3863_RS05845_lanthipeptide
18
I N S C T F L F H E D E V P E E L Q K D N P F L D K S G R D E G L
50
I N S C T F L F H E D E V P E E L Q K+N P F L K+G E G L
1
I N S C T F L F H E D E V P E E L Q K N N P F L Y K N G G K E G L
33
17.9%
NZ_CP117772.1:
Lanthipeptides: allorf_0438568_0438768_lanthipeptide
9
I M L I A T F G A I N S C T F L F H E D E V P E E L Q K D N P
39
+ L+ G I+S + F H+ E K+N P
16
L A L L V I A G F I S S S L W F F H K H I E H E T C S K N N P
46
with 6 more sequence matches
16.0%
NZ_MIFM01000001.1 and 1 other:
NZ_NINI01000009.1 Lanthipeptides: CEV12_RS07225_lanthipeptide
Lanthipeptides: BHL22_RS00375_lanthipeptide
15
F G A I N S C T F L F H E D E V P E E L Q K D N
38
F G++ C E+E+P E+L+ ++
1
F G S L Y M C W G F L D E E E I P E K L K G N D
24
14.0%
NZ_JAQEYW010000015.1:
Lanthipeptides: PG422_RS12370_lanthipeptide
17
A I N S-C T F L F H E D E V P E E L Q K
36
A+N S C ++H+ ++P+E+++
6
A V N S R C V C I Y H Q P K M P K E M K Q
26
14.0%
NZ_LR134483.1 and 1 other:
NZ_LR134483.1 Lanthipeptides: EL241_RS01765_lanthipeptide
Lanthipeptides: EL241_RS01765_lanthipeptide
18
I N S C T F L F H E D-E V P E E L
34
+ C F L ++ E+P+E L
3
V R Q C C F L L S D E I E I P D E L
20
12.0%
NZ_FNFB01000016.1:
Lanthipeptides: allorf_081491_081622_lanthipeptide
34
L Q K D N P F L D K S G R D E
48
+ +D+P F L + R D+
4
V A Q D S P F L T F A A R D D
18
12.0%
NZ_JANYMP010000013.1:
Lanthipeptides: allorf_203043_203156_lanthipeptide
19
N S C T F L F
25
N S C T F+F
8
N S C T F I F
14
8.0%
NZ_CP084014.1 and 1 other:
NZ_CP094679.1 Lanthipeptides: K5I24_RS13140_lanthipeptide
Lanthipeptides: LCQ72_RS00060_lanthipeptide
19
N S C T F L F H E D E V P E E L Q K
36
+ C ++H+ ++P+E+++
2
S R C V C I Y H Q P K M P K E M K Q
19
allorf_094339_094437
Leader:
MVKEIVCMYLLVRAGA
Core:
L L L L Y L L N C F T L Y I F I
Core with dehydrations:
L L L L Y L L N Cys F Dhb L Y I F I

#### antiSMASH-DB 4.0 matches for allorf_094339_094437

100.0%
NZ_JAGKQT010000007.1:
Lanthipeptides: allorf_094339_094437_lanthipeptide
1
L L L L Y L L N C F T L Y I F I
16
L L L L Y L L N C F T L Y I F I
1
L L L L Y L L N C F T L Y I F I
16
43.8%
NZ_JH992901.1:
Lanthipeptides: allorf_3871595_3871663_lanthipeptide
5
Y L L N C F T L Y I F I
16
Y N C F T L I +
1
Y S P N C F T L N I I V
12

#### Legend:

Dha: Didehydroalanine
Dhb: Didehydrobutyrine
Transcription Factor Binding Sites
Detailed information for Transcription Factor Binding Site hits, including surrounding genes where applicable.
The strand of the match is shown by an arrow underneath the match.
Detailed documentation is available here.
Binding sites found:
CRP
Description: Cyclic AMP receptor protein
Species: Escherichia coli str. K-12 substr. MG1655
Score: 18.06 out of 19.26
Confidence: strong
Lanthipeptides
TFBS Finder
Core peptide predictions
Lists the possible core peptides in the region. Each core peptide lists the number of lanthionine bridges, possible molecular weights, and the scores for cleavage site prediction and RODEO.

J2M30_RS09845 - Class II
  Cleavage pHMM score: -0.10
  RODEO score: 0
  Monoisotopic mass: 2717.4 Da
  Molecular weight: 2719.1 Da
  Number of bridges: 3
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    2737.1 Da N = 1
    2755.2 Da N = 2
    2773.2 Da N = 3
    2791.2 Da N = 4
    2809.2 Da N = 5
    2827.2 Da N = 6
    2845.3 Da N = 7
J2M30_RS09860 - Class II
  Cleavage pHMM score: -5.80
  RODEO score: 0
  Monoisotopic mass: 3773.8 Da
  Molecular weight: 3776.2 Da
  Number of bridges: 4
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    3794.2 Da N = 1
    3812.2 Da N = 2
    3830.2 Da N = 3
    3848.3 Da N = 4
    3866.3 Da N = 5
J2M30_RS09870 - Class II
  Cleavage pHMM score: -5.40
  RODEO score: 0
  Monoisotopic mass: 5505.7 Da
  Molecular weight: 5509.2 Da
  Number of bridges: 1
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    5527.2 Da N = 1
    5545.2 Da N = 2
    5563.2 Da N = 3
    5581.3 Da N = 4
allorf_071326_071475 - Class II
  Cleavage pHMM score: -6.10
  RODEO score: 0
  Monoisotopic mass: 2210.1 Da
  Molecular weight: 2211.5 Da
  Number of bridges: 1
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    2229.5 Da N = 1
J2M30_RS09845 - Class II
  Cleavage pHMM score: -0.10
  RODEO score: 0
  Monoisotopic mass: 2717.4 Da
  Molecular weight: 2719.1 Da
  Number of bridges: 3
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    2737.1 Da N = 1
    2755.2 Da N = 2
    2773.2 Da N = 3
    2791.2 Da N = 4
    2809.2 Da N = 5
    2827.2 Da N = 6
    2845.3 Da N = 7
J2M30_RS09860 - Class II
  Cleavage pHMM score: -5.80
  RODEO score: 0
  Monoisotopic mass: 3773.8 Da
  Molecular weight: 3776.2 Da
  Number of bridges: 4
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    3794.2 Da N = 1
    3812.2 Da N = 2
    3830.2 Da N = 3
    3848.3 Da N = 4
    3866.3 Da N = 5
J2M30_RS09870 - Class II
  Cleavage pHMM score: -5.40
  RODEO score: 0
  Monoisotopic mass: 5505.7 Da
  Molecular weight: 5509.2 Da
  Number of bridges: 1
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    5527.2 Da N = 1
    5545.2 Da N = 2
    5563.2 Da N = 3
    5581.3 Da N = 4
allorf_094339_094437 - Class II
  Cleavage pHMM score: -6.90
  RODEO score: 0
  Monoisotopic mass: 1956.1 Da
  Molecular weight: 1957.5 Da
  Number of bridges: 1

TFBS definitions
Shows descriptions for Transcription Factor Binding Site models

Regulator | Description
--- | ---
CRP | Cyclic AMP receptor protein