LOCUS       NZ_CP076538            22559 bp    DNA     circular CON 16-DEC-2024
DEFINITION  Amycolatopsis aidingensis strain YIM 96748 chromosome, complete
            genome.
ACCESSION   NZ_CP076538
VERSION     NZ_CP076538.1
KEYWORDS    RefSeq.
SOURCE      Amycolatopsis aidingensis
  ORGANISM  Amycolatopsis aidingensis
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Pseudonocardiales; Pseudonocardiaceae; Amycolatopsis.
REFERENCE   1  (bases 1 to 7657695)
  AUTHORS   Li,R.
  TITLE     YIM 96748 draft genome
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 7657695)
  AUTHORS   Li,R.
  TITLE     Direct Submission
  JOURNAL   Submitted (08-JUN-2021) Yunnan University, Yunnan Institute of
            Microbiology, 121 Street, Yunnan 650000, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdevono v. 2.04
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 57.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_018885265.1-RS_2024_12_16
            Annotation Date                   :: 12/16/2024 14:59:15
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,118
            CDSs (total)                      :: 7,060
            Genes (coding)                    :: 6,941
            CDSs (with protein)               :: 6,941
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 44 of 119
            Pseudo Genes (incomplete)         :: 87 of 119
            Pseudo Genes (internal stop)      :: 2 of 119
            Pseudo Genes (multiple problems)  :: 13 of 119
            CRISPR Arrays                     :: 4
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 14:56:56
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 7112937
            Orig. end                         :: 7135496
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP076538.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22559
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="crocagin"
                     /region_number="34"
                     /rules="(PhyH and Carbam_trans_N)"
                     /tool="antismash"
     cand_cluster    1..22559
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PhyH and Carbam_trans_N)"
                     /kind="single"
                     /product="crocagin"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22559
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12559](+)"
                     /cutoff="10000"
                     /detection_rule="(PhyH and Carbam_trans_N)"
                     /neighbourhood="10000"
                     /product="crocagin"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12559
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PhyH and Carbam_trans_N)"
                     /neighbourhood="10000"
                     /product="crocagin"
                     /protocluster_number="1"
     gene            complement(237..662)
                     /locus_tag="KOI47_RS32670"
     CDS             complement(237..662)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1164: transposase
                     IS3/IS911 family protein"
                     /gene_kind="other"
                     /inference="COORDINATES: protein motif:HMM:NF013677.5"
                     /locus_tag="KOI47_RS32670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="transposase"
                     /protein_id="WP_216210941.1"
                     /transl_table=11
                     /translation="MGRRGYPPEFRWKVLDLVEAGRRVADVARDLGISDRSIYTWRRQD
                     RIDRGLEPGLSSVEKAELTAAKQRIAELEAELAVHRRAGKLLKEAVPQKLGTLRSRRWL
                     RKACRSRWPAGYLGVGVRLLRLAIPATNQPGRSGTPG"
     gene            complement(835..>1098)
                     /locus_tag="KOI47_RS32675"
                     /pseudo=""
     CDS             complement(835..>1098)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011689697.1"
                     /locus_tag="KOI47_RS32675"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="FLDYDPEIRRVLCSTNAIESLNARCRKAVRARGHFPTEQAALKCL
                     YLVTRSLDPTGKGQARWTMRWKPALNAFATTFGDRWPSAQKY"
     gene            1162..1395
                     /locus_tag="KOI47_RS36575"
     CDS             1162..1395
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1164: transposase
                     IS3/IS911 family protein"
                     /gene_kind="other"
                     /inference="COORDINATES: protein motif:HMM:NF013677.5"
                     /locus_tag="KOI47_RS36575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="transposase"
                     /protein_id="WP_408629873.1"
                     /transl_table=11
                     /translation="MAVIRRVAGQLDVHPEALRTWVKRAEIDAGTAAGRTSDDAARIAE
                     LEREVRELRRANEILKTASAFFAAAELDRKTK"
     gene            1966..3831
                     /locus_tag="KOI47_RS32685"
     CDS             1966..3831
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1041:
                     transcriptional regulator, SARP family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF013124.5"
                     /locus_tag="KOI47_RS32685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="AfsR/SARP family transcriptional regulator"
                     /protein_id="WP_216210946.1"
                     /transl_table=11
                     /translation="MTGTFQQPDLVQEAAPRLRILGPLEVEGLAAPVHVTAPRQRVLLA
                     MLLLGANQVISNDRLADAVWGGSPPNTVRSQIQICVAALRQQLAETRLGTCIETKPQGY
                     LLRTADHELDAHIFERFAEAGHIAAKHGDHMSASAAYRSALALWRGTPLEDIDSPVVQA
                     ALVRLVEQRMTVIEDCFRVELELGRHHQLIGELKQLVAQNPLRERLRVLLMLGLHRAGR
                     KAEALEEYLAARRVLMDELGLEPSLELRELERGILADDPGLMLPADVEVRVPRSSAPSM
                     LPSDISDFTGREQFMARSRQYLVSASHTRATPILAITGGGGVGKSAAAVHLAHQVTTAF
                     PDGVLYADLGGSSDRADASEILLQFLRALGVPDERIPARTAERAALYRTTATGKRVLVL
                     LDDAVDERQVEPLLPGHPSSGVVITSRARLVGLPGARLFSMEALDRHDALRLLGTLVGR
                     ERVAVEPKAAQELVERCDALPLALRIAATRLTVRPHWTIEQIVRLLADGTRRLDVLAHG
                     GLSVRASIEVTYRRLDAQAKRLLLRLASLEDSEFDAGTATSLLGLDELEATNILETLVD
                     AYLVRVVRGTAGETRYRLSGLVRAFAAEPQSVQGRAARQARDPAA"
     gene            3895..5406
                     /locus_tag="KOI47_RS32690"
     CDS             3895..5406
                     /NRPS_PKS="Domain: Beta_elim_lyase (196-339). E-value:
                     4e-08. Score: 24.8. Matches aSDomain:
                     nrpspksdomains_KOI47_RS32690_Beta_elim_lyase.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1180: Decarboxylase, pyridoxal-dependent"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012503.5"
                     /locus_tag="KOI47_RS32690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="pyridoxal-dependent decarboxylase"
                     /protein_id="WP_216210947.1"
                     /transl_table=11
                     /translation="MVANRNLWETGYLPAGGADGLERLRELVNGGLDILRDTASRRVGP
                     VAPGGPAGVAAAAAELFRRLDPAGGNRDRDAFGDLVRAYATWSVDLTHHAAVARMQCAP
                     AVEAAAADLIATVTNQSLHAWESGPFALELERWLVSWLVALVGYDPGAGGTFTAGGSVS
                     NLMALLLARDHNLSRRVGAATFRDGVTGLGVRPVVLCTAATHFSIARSVGIVGLGSGSI
                     LRVPDDEKGRMIPDAADRMLAELPDDRPPVALVACAGTTDFGEVDPLPELAAIARRHGV
                     WLHADAAYGGGALFSQRLKTMLTGIEQVDSITLDLHKFGWTPASSGVFLVRRAEFLDSW
                     SGQTTTLNADDDKVAGYYGRYESSLQATRRVDALKIATVLLTLGEQGLGDMVEACHRQA
                     LHAARRILGEPRLELAAEPALSTVVFRYLPESAGDADAFNGELRRRLMAEGKVLMARTR
                     VPRPDGDPVFLKLMLLNPETTSDQIDEIVADVLAVAARMETAVPA"
     aSDomain        4483..4911
                     /aSDomain="Beta_elim_lyase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_KOI47_RS32690_Beta_elim_lyase.1"
                     /evalue="4.00E-08"
                     /label="KOI47_RS32690_Beta_elim_lyase.1"
                     /locus_tag="KOI47_RS32690"
                     /protein_end="339"
                     /protein_start="196"
                     /score="24.8"
                     /tool="antismash"
                     /translation="VVLCTAATHFSIARSVGIVGLGSGSILRVPDDEKGRMIPDAADRM
                     LAELPDDRPPVALVACAGTTDFGEVDPLPELAAIARRHGVWLHADAAYGGGALFSQRLK
                     TMLTGIEQVDSITLDLHKFGWTPASSGVFLVRRAEFLDS"
     gene            5539..6678
                     /locus_tag="KOI47_RS32695"
     CDS             5539..6678
                     /EC_number="1.14.19.-"
                     /GO_process="GO:0006629 - lipid metabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012699.5"
                     /locus_tag="KOI47_RS32695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="fatty acid desaturase"
                     /protein_id="WP_216210948.1"
                     /transl_table=11
                     /translation="MLPAVFALPLTLLTGKPHAGQRPFRITPTVHLVNAMLSVSSGLAL
                     SAGALAWTGWWLLLLLPGWAMTLHGIRNLRMMIFHQCAHRNMWGRRKLDALLGRVLSAL
                     LLIQHYDTYSAEHVRDHHALHHMTLRDPTVQAFLLTLRLRPGMTRRQMWRMAMAKTFSP
                     GFHARFFVARICSYCSAATRIERTVFLCSVLTLAALVSWLGLWTFVLVAWLPPGTVFFQ
                     MSNVLRLCVKHTFPAAGVTERRGRDYFAGLTNAIFLGEAAPAPGLAWPKRMRAWARWWL
                     RMAFVHFPARYLVLTGDTVCHDFHHRYPMSNNWANYIFAREADFTKGHPGWPPYRHVWG
                     LAAGVNVVFDSLAAADATEYDPERLTAVNRRDLFLAFDD"
     misc_feature    5719..5721
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            6713..7150
                     /locus_tag="KOI47_RS32700"
     CDS             6713..7150
                     /GO_function="GO:0031419 - cobalamin binding [Evidence
                     IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013226629.1"
                     /locus_tag="KOI47_RS32700"
                     /note="Presence of a B(12) (cobalamin)-binding domain
                     implies dependence on cobalamin itself, in one of its
                     several forms, or in some unusual lineages, dependence on a
                     cobalamin-like analog.; Presence of a B(12)
                     (cobalamin)-binding domain implies dependence on cobalamin
                     itself, in one of its several forms, or in some unusual
                     lineages, dependence on a cobalamin-like analog.; Presence
                     of a B(12) (cobalamin)-binding domain implies dependence on
                     cobalamin itself, in one of its several forms, or in some
                     unusual lineages, dependence on a cobalamin-like analog.;
                     Presence of a B(12) (cobalamin)-binding domain implies
                     dependence on cobalamin itself, in one of its several
                     forms, or in some unusual lineages, dependence on a
                     cobalamin-like analog.; Presence of a B(12)
                     (cobalamin)-binding domain implies dependence on cobalamin
                     itself, in one of its several forms, or in some unusual
                     lineages, dependence on a cobalamin-like analog; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /product="cobalamin-dependent protein"
                     /protein_id="WP_232376406.1"
                     /transl_table=11
                     /translation="MTGEDRQGAPLVILGVAESDAHAVANRLIEMYLRAQGYLVVNLGV
                     CTPLTDFADALAAHPEAVAVLIGSLNGHAYDDLRDLPALRAAGWLDRPVVVGGNLSVDG
                     AEGHAGLHALGVDHVARDEHELLALLDQLCSPVARSLGEGR"
     misc_feature    7162..7177
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: medium, score: 21.58"
                     /tool="antismash"
     gene            7252..8574
                     /locus_tag="KOI47_RS32705"
     CDS             7252..8574
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013226630.1"
                     /locus_tag="KOI47_RS32705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="methylaspartate mutase"
                     /protein_id="WP_232376407.1"
                     /transl_table=11
                     /translation="MDVLRAADASGRPVIQPRCGVGGHQQMVDLLRDLERVDSAILSVT
                     IDSYTRLGRFGSAERLLHDRPADLNGYPLVAHGWQRGRDLVSAVETPLEVRHGSPDARR
                     LFAVSVASGILSFEGGGLGYNLPYSKNVPLSTSLDAWRRVDASCGLLSREGVIVDRELF
                     GTLTAVLVPPSISLAVTMLEARAAAGEGVTCLSIAYPQGGQVHQDVAALRAIRPLARRY
                     VSAEVEVYPVLHEFMGAFPRTTTAADALILHGGLVARLGGATKIVSKTSQEARRIPDVV
                     ANAHGVRTAALGASSLFDFVEVDEARVAEEQYWIEREVAELVEPVLDDGDLTGAIERAF
                     RAGRLDVPFSASLHARSDVVPCRDRYGAIRYGTLGALPFSGAALRRNAASLAESPEPRD
                     GRSQSPIERVSADINYFVNLDGTRPRPLPAVPSPPFARKSR"
     gene            8571..10004
                     /locus_tag="KOI47_RS32710"
     CDS             8571..10004
                     /NRPS_PKS="Domain: Aminotran_3 (46-385). E-value: 2.9e-92.
                     Score: 301.2. Matches aSDomain:
                     nrpspksdomains_KOI47_RS32710_Aminotran_3.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1013: aminotransferase class-III"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020497043.1"
                     /locus_tag="KOI47_RS32710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="aspartate aminotransferase family protein"
                     /protein_id="WP_216210950.1"
                     /sec_met_domain="Aminotran_3 (E-value: 1.8e-91, bitscore:
                     305.5, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKVPSTPKNDQAISPAERDRLVREAHRAHVFQPWSAQAHVAPFPV
                     AGAEGRYFWDHQGNRYLDFSSQFVNLNIGHAHPKVVAAIKEQAERLCTIAPHFANEQRS
                     EAARLIAELTPGDLTKIFFTSGGAEANEHAVRMTRLFTGRHKVLSAYRSYHGATSTAIH
                     LTGDPRRWPNDTGAAGVVHFVPPYLYRSAFDARTEAEECRRALDHLEQMICFEGPRTIA
                     AVILEPVIGTGGVLVPPAGYLPGVRALCDEHGIALIVDEVMTGFGRTGRWFGVDHWDVV
                     PDLLTFSKGVNSGYVPLGGVAITARIADFFADRPYPGGLTYSGHPLACAAAVAATRAMA
                     DERVVEHASWLGEQVLGPGLRDIAEAHPCVGEVRGLGVMWAIELVRDRDTREMLVPYAA
                     TGTDTAPVDEVMAECQRRGLWPFANFNRVHVLPPCNTTEDEARKGLGMLDEALTVADSR
                     VTAGSRRGRPRGPRTGDIE"
     aSDomain        8709..9725
                     /aSDomain="Aminotran_3"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_KOI47_RS32710_Aminotran_3.1"
                     /evalue="2.90E-92"
                     /label="KOI47_RS32710_Aminotran_3.1"
                     /locus_tag="KOI47_RS32710"
                     /protein_end="385"
                     /protein_start="46"
                     /score="301.2"
                     /tool="antismash"
                     /translation="GAEGRYFWDHQGNRYLDFSSQFVNLNIGHAHPKVVAAIKEQAERL
                     CTIAPHFANEQRSEAARLIAELTPGDLTKIFFTSGGAEANEHAVRMTRLFTGRHKVLSA
                     YRSYHGATSTAIHLTGDPRRWPNDTGAAGVVHFVPPYLYRSAFDARTEAEECRRALDHL
                     EQMICFEGPRTIAAVILEPVIGTGGVLVPPAGYLPGVRALCDEHGIALIVDEVMTGFGR
                     TGRWFGVDHWDVVPDLLTFSKGVNSGYVPLGGVAITARIADFFADRPYPGGLTYSGHPL
                     ACAAAVAATRAMADERVVEHASWLGEQVLGPGLRDIAEAHPCVGEVRGLGVMWAIELV"
     gene            10001..11707
                     /locus_tag="KOI47_RS32715"
     CDS             10001..11707
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     crocagin: Carbam_trans_N"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015102407.1"
                     /locus_tag="KOI47_RS32715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="carbamoyltransferase N-terminal domain-containing
                     protein"
                     /protein_id="WP_216210951.1"
                     /sec_met_domain="Carbam_trans_N (E-value: 4.2e-67,
                     bitscore: 225.7, seeds: 4, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIICGLKLTHDGAVALLDGDRLVFSVEIEKLANNRRYSDMPDLRV
                     IPEILASFGCRVADVDEWVIDGWDGDVSRDLELADHGRAITLTVGPYRESASSPSLTSP
                     SLTGQFTIDGKELVYTSYPHAAGHLAGTYCSSPFADRGEPSFVLIWDGGLFPRLYWVDP
                     DRGVDNGGELFPLIGHAYAMAGLSFGPFRGLPQKTKTDELSVAGKLMAYIALGKADTPV
                     IDVLRETFHETFESKTPEAVRYRETIGGFGSLFEPSRAPVNAFLGKVRDRVEALGVPDE
                     DVLASFHQFLEELLVERIEAKVREWKGDGPWNLCFAGGCALNINWNSALRARSLFGEMW
                     VPPFPNDSGSALGVATLGMIQHRGIGPITWHPQSGSALGPVTEVPCGWTSRRAAAAEVA
                     RLLHESGEPVVVLEGRAELGPRALGGRSIIAPAADPAMKDRLNDIKNRESYRPVAPICL
                     VEEAPKIFDPGTPDPYMLFDHDVREGWASRIPAVIHLDGTARLQTVSSDDFPEIAALLA
                     EYHKLSGIPVLCNTSANFNGSGFFPDVASAIEWGRVARVWSEGVLYERTGS"
     gene            11723..12559
                     /locus_tag="KOI47_RS32720"
     CDS             11723..12559
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     crocagin: PhyH"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF017532.5"
                     /locus_tag="KOI47_RS32720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="phytanoyl-CoA dioxygenase family protein"
                     /protein_id="WP_216210952.1"
                     /sec_met_domain="PhyH (E-value: 2.3e-32, bitscore: 111.6,
                     seeds: 39, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRLTKPQLDRYHRDGFLELDRALSAEETQVLREAFARDCDVPGPH
                     RVLEDDRTVRAVYASHQRQREFAALVRDRRLLAPARQLLGDQVYVYQLKINSKSPFTGE
                     GWSWHQDYPAWRIADSLAEPRQVNVAVFLDDVDEFNGPVVFVPGSHRFGPLHLDRTPDA
                     KSDQHIDPDDIALTREQLAKLVDAGAMVAPKGPAGTVVFFSSEVVHGSGVNISPYPRHL
                     LIVTYNDVSNPPSWRGEPRPGYVVCRDNDPLTYLDDPLGPWTVRRAATVPVSEDIR"
     misc_feature    11999..12001
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            12823..14031
                     /locus_tag="KOI47_RS32725"
     CDS             12823..14031
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="KOI47_RS32725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_216210953.1"
                     /transl_table=11
                     /translation="MDDAGIFSFAHDLEALFGLLVALPSRLFDGDLGRFCEAVGITARQ
                     AALMARLPDPAPCYGRADAYHDGTGLKLLEFNVGSEIGGIDTAHVALALTQVDAFRAFA
                     EENELAYVDTGKRVTDAIRAAAEPLTGGTDPVVALVEPDGLMHEYLEEDRSFQQMLSDL
                     GLDTLLGEVGELQHRAGRLHLHGRPVDIVLRYFTEKEIAGQTASERAVEMVARAHEEGR
                     VVLWTTMRSKLAASKACFGLLSDSRCREAFSADEIALIERVLPWTRILDDVETEVEGQT
                     VRLLEYCREARTGLLIKPHLGHDGVGIVAGWRVTDAEWRDALESAAAAGAIVQRRVISR
                     PEPMIDPESGEVEHWGCTWSVFVVPDGYAGTTMRTVTLDNRSERRCLAPIFQYPASTYG
                     GAR"
     misc_feature    13324..13326
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            14028..14873
                     /locus_tag="KOI47_RS32730"
     CDS             14028..14873
                     /GO_function="GO:0016829 - lyase activity [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF015297.5"
                     /locus_tag="KOI47_RS32730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="CoA ester lyase"
                     /protein_id="WP_216210956.1"
                     /transl_table=11
                     /translation="MKYTRYCRSMLSTPALQTDRFRKSHEADADICMVDLEDSIPPWDK
                     DTARNLAARFFVPPAPARCAIRINTLTTPDGLRDLLAIRDYPTKPAIVVVPMVESPRDI
                     EVAESVLVRTCPDVEFLAVVETPRGVENANAIAAASPRLRALIFGSADYSFLAGVRLAW
                     DTLVHARARLVNAARAAGIEVIDAPTFEISEHATIKEDAVRAHDLGFSGKIAIHPRQVP
                     VINEAFSPDTATLEKARRIVAAGQENGRKIAVVDGAMVGIPFFEASQHLIEEFGDLLHS
                     "
     gene            14888..16150
                     /locus_tag="KOI47_RS32735"
     CDS             14888..16150
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Aminotran_1_2 (60-397). E-value:
                     3.6e-10. Score: 31.4. Matches aSDomain:
                     nrpspksdomains_KOI47_RS32735_Aminotran_1_2.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1109: 8-amino-7-oxononanoate synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF005697.0"
                     /locus_tag="KOI47_RS32735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="WP_216210958.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 4.2e-08, bitscore:
                     31.4, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTDTGALERVLGAHRYRNTEKMLRMSDPVWLAAASEGLINLNVE
                     AASNNKMIIPESGHEFINLCSSAYLGLNFHPKVIEGAIDVLREAGTTGLLTSNARIRHR
                     TLGRLEEELGELFRATALVGVSCTALSFGILPLVAAGYLAEGGARVMVYDRFCHFSMAY
                     VKPITADESLVLTAPHNDLNYLEDVCKKYPRVAYIADGAYSMGGAAALDGLQELQDRYG
                     LFLYLDDSHSLSITGEHGEGFTRSQIEMNPLSIIVSTLNKGFGSNGGVAMLGRPELYPF
                     LTRHGGPIGWSQNIEVTSVGASLASAEIHRSSELGELQHKLQENIDYFDQRYPTKFAGN
                     NLPVRLVPVGDADRSVRLSGELFRRGYYSSAVFFPIVPRGKAALRVMIRADISKDALGG
                     FIDTVEELTADSDADEAPAHG"
     aSDomain        15068..16078
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_KOI47_RS32735_Aminotran_1_2.1"
                     /evalue="3.60E-10"
                     /label="KOI47_RS32735_Aminotran_1_2.1"
                     /locus_tag="KOI47_RS32735"
                     /protein_end="397"
                     /protein_start="60"
                     /score="31.4"
                     /tool="antismash"
                     /translation="FINLCSSAYLGLNFHPKVIEGAIDVLREAGTTGLLTSNARIRHRT
                     LGRLEEELGELFRATALVGVSCTALSFGILPLVAAGYLAEGGARVMVYDRFCHFSMAYV
                     KPITADESLVLTAPHNDLNYLEDVCKKYPRVAYIADGAYSMGGAAALDGLQELQDRYGL
                     FLYLDDSHSLSITGEHGEGFTRSQIEMNPLSIIVSTLNKGFGSNGGVAMLGRPELYPFL
                     TRHGGPIGWSQNIEVTSVGASLASAEIHRSSELGELQHKLQENIDYFDQRYPTKFAGNN
                     LPVRLVPVGDADRSVRLSGELFRRGYYSSAVFFPIVPRGKAALRVMIRADISKDAL"
     gene            16143..16670
                     /locus_tag="KOI47_RS32740"
     CDS             16143..16670
                     /GO_function="GO:0016829 - lyase activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020634809.1"
                     /locus_tag="KOI47_RS32740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MaoC family dehydratase"
                     /protein_id="WP_216210961.1"
                     /transl_table=11
                     /translation="MDEGPTGYRRVGVQRYRETVGFYYEEFTVGDVFEHRPGRTITEMD
                     NVLMSMLGMNASPLHIDAAYMKHTRWEQPIVSSLVTLGIVGGMTARSTSGRAVANLGWD
                     NIRLLSPVLAGDTLYAETEIMMKRPSQSYTDHGIVGCRTLGIKSTGEKVISFDRSFLVP
                     MREHSRDAEVGY"
     gene            complement(16828..18290)
                     /locus_tag="KOI47_RS32745"
                     /pseudo=""
     CDS             complement(16828..18290)
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020641976.1"
                     /locus_tag="KOI47_RS32745"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="IS1634 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MQIVHSSRQGSRDIEHIGSAHDDVELELLRTVARQRMTAGQGELE
                     LSLDASPEAGGPLPITASRMGHLWDALSSAYEVLGFDAAADGDEVFRQLVLARIIEPSS
                     KLDALRVLEEAGIAPVSYRTLKRRLPLYAADAWRERLAALCAHHVGLGPATYVLYDVTT
                     LYFETDTGDGFRESGFSKERRLEPQITVGLLTDAAGFHSWSTRSRATRPRSPRCCPRSP
                     RSWPPTVCTTWSSSPMPE"
     misc_feature    complement(18213..18215)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(18443..19015)
                     /locus_tag="KOI47_RS32750"
     CDS             complement(18443..19015)
                     /EC_number="2.7.7.49"
                     /GO_function="GO:0003723 - RNA binding [Evidence IEA]"
                     /GO_function="GO:0003964 - RNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006278 - RNA-templated DNA biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012307.5"
                     /locus_tag="KOI47_RS32750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="reverse transcriptase/maturase family protein"
                     /protein_id="WP_216210964.1"
                     /transl_table=11
                     /translation="MLKVNKDGEVREMRDAATVLEIIRERGRRGLPLERVYRCLFNPDL
                     FLLAYGKLYRNKGAMTPGVTSETVDGMNLGKIEAIITVLRQERYRWTPVRRTYIEKKNS
                     SKKRPLGLPTWSDKLLQEVLRLILEAYYEPQFSDRSHGFRPGRGCHTALQEIYHQWHGT
                     VWFIEGDITDCFGSLSHSIMRSVLAET"
     gene            complement(19561..21024)
                     /gene="ltrA"
                     /locus_tag="KOI47_RS32755"
     CDS             complement(19561..21024)
                     /EC_number="2.7.7.49"
                     /GO_function="GO:0003964 - RNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0000373 - Group II intron splicing
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="ltrA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013672260.1"
                     /locus_tag="KOI47_RS32755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="WP_216210966.1"
                     /transl_table=11
                     /translation="MPKDAPLNSGALEQPDVGSFRRVSEMQAKLHRWASADPGRRFDDL
                     FNLVHDPATLRVAWERVASNAGARTAGSDGVTVARIERDIGALEFLGGIRIVVKDGSFR
                     PQPVRERLIPKPVGSGKVRRLGIPTVIDRVVQAALKLVLEPIFEADFHPVSFGFRPKRR
                     AHDAIADIHLFGSRGYEWVLDADIEACFDTIDHVALMDRVRARVTDKRVLTLVKSFLKA
                     GVLTELGEERDTPTGTPQGGILSPLLANIALSVLDEYMHRDWRPGGWMSTENRRHRHRR
                     LGLPTWRLVRYADDFVVMVFGTRDHVVALREEIAQVFAPMGLRLSPTKTRIVHIRDGFD
                     FLGFRIRWRIKKGTRDQWRLYTFVGDRPVRSLKARIRALTRRTSQQDLRAVLIRINRIT
                     RGWAEYFRHAVAKHTFDRLAYFIWWRIVRWVKTKRRWRWKDVHRWLRTPTGWRPIAADG
                     IELRNIAATPVTRYRRRSIPNPWPCTNHA"
     gene            complement(<21615..21972)
                     /locus_tag="KOI47_RS36020"
                     /pseudo=""
     CDS             complement(<21615..21972)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020639690.1"
                     /locus_tag="KOI47_RS36020"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MAAEMIKQAQEQGMALTGPDGLLGQLTKTVLEIRAGRGDDRAPGA
                     CQAR"
ORIGIN
        1 acgattcggt gcccctgccg tgaagtcacg tttgacccag tcccgagcga tctcatccgg
       61 cttggcgcgt tgccacttcg gccggcccat ggccccggca agcccggctc ggtgcatgag
      121 catctccacc gcaccatgcc cgaccacgac gccacggccc agccgcagtt cggcgtgcac
      181 ccggcggctg ccgtggatac cgtgcgaact ctgatgaatc tcggtgatca cctcggtcag
      241 ccaggcgtgc cggatcgacc gggctgatta gtggccggga tcgccagtcg tagaagccgg
      301 actccgacac ccaagtaccc ggcaggccac ctggatcggc aggccttcct cagccatcgc
      361 cgcgatcgca gcgtaccgag cttttggggc accgcctcct tcagcaactt cccggcccgc
      421 cggtgcacag ccagttcggc ctccaactcg gcgatacgct gcttcgccgc ggtcagctcg
      481 gccttctcaa cgctgctcag cccgggttcc agcccgcgat cgatccgatc ctgccgcctc
      541 caggtgtaga tcgaccggtc gctgataccc agatcacgcg cgacgtcggc aaccctgcga
      601 ccggcctcga ccaagtccag caccttccat cggaactccg gcggataccc acgccgtccc
      661 ataccaccct ctccttcaag atcgagtggc acaagaatcc aacaactcgc ctccgaagaa
      721 gccgggacac accactccca ttccttgagg agaatggcgt catggcacga tcttcacggc
      781 acccggctga gagagtgggg tctgtaacgg aatcggtggg ttcggcattg ctggctagta
      841 cttctgtgcg ctcggccaac ggtcaccgaa cgtggtcgcg aacgcgttga gcgctggctt
      901 ccaccgcatc gtccacctcg cctggccctt gccggtcggg tcgagcgagc gggtgaccag
      961 gtacagacac ttcagcgcgg cttgctcggt cgggaagtga cctcgtgccc gcacggcctt
     1021 acgacaccgc gcgttcagcg actcgatcgc gttggtggag cacaacacac gcctaatttc
     1081 cgggtcatag tccagaaacg atgagctgcg tgagagggcg acgcggatgg cgttggcggg
     1141 atcgcggccg aggggcggcg gatggcagtc atccgccggg tcgcgggcca gttggatgtg
     1201 cacccggagg cgttgcggac atgggtcaag cgcgccgaga tcgacgccgg cacggcggcc
     1261 ggccgcacca gcgacgatgc tgcacggatc gctgagctgg aacgtgaggt gcgtgagttg
     1321 cggcgggcga acgagatcct gaaaacggcc tcggcgtttt tcgccgccgc ggagctcgac
     1381 cgcaagacca aatagacctt gacgtttccg ctcgtcggag ggaggttccg ctcgcggtgg
     1441 tcatcgacta tatcgacggc caccgtgagc gtgttgttga ggggaagaaa ctctgggtcg
     1501 agccgatctg cgccgtcttg aacgatgcgg gtgtgcagat cgccccgaga acgtattgga
     1561 cagcgaagaa acgcgcgccg tcgaaacgcg ttcttcgcga tgcggagctg ctcaccgaga
     1621 ttgagcgtca aacatccgtc gtttcgcatg gcaccacccg gttggcccaa agatcatcga
     1681 agtcagcctg gaagcacccg cgctgtgatc tactgtgttc cggagggcct ttcgtcttcg
     1741 cgtgtcggcg agtgtttcgg gctcggctgg ccaggtgtct tacccgcggt cgacctcggc
     1801 cgaggggcgg gcaggccaga cccatcctgc ggcgcgatgg cggcagggac atgaaggacg
     1861 ggttcgccgc atcgttgcgg ccgtagttat cagggggaac acttgaagtt aggggctgac
     1921 aatgtccaca accgaagtgc aagaccaagt cacgacccag gcgggatgac ggggacgttt
     1981 cagcagccgg acctcgtgca ggaggccgcc ccacggttga ggatcctcgg cccgctcgag
     2041 gtggaaggct tggccgcgcc tgtacatgtc actgcgcccc gtcagcgggt cctcctcgct
     2101 atgctacttc tcggcgccaa ccaggtgatc tcgaacgacc ggctggccga tgcagtgtgg
     2161 ggtggctccc caccgaacac cgtccgcagt cagatccaga tctgcgtggc tgcgctgaga
     2221 caacagctcg ccgagacgcg gctggggact tgcatcgaga ccaagccaca aggctacctg
     2281 ttgcgcacag cagaccacga gctcgacgct catatcttcg aacgtttcgc ggaagccggg
     2341 cacatcgcgg ccaagcacgg ggaccacatg agtgcctcgg cggcctaccg cagtgcgctg
     2401 gcgctatggc gaggcactcc gctagaggac attgacagcc cggtagtaca agctgcgctg
     2461 gtcaggctcg tcgaacagcg catgacagtg atcgaggact gtttccgggt cgagctcgag
     2521 ctgggccgtc accaccagct gatcggtgag ttgaaacagc ttgtcgccca gaacccgctg
     2581 cgcgaacggc ttcgtgttct gctcatgctg ggcctgcaca gggcaggccg caaggcggag
     2641 gcgctggaag agtacctggc ggcgcgccgg gtcctgatgg acgagctggg actcgaaccc
     2701 agtctggaac tccgtgagct cgaacgaggc atcctcgctg acgatcctgg acttatgctg
     2761 cccgccgacg tcgaggtccg agtgccgagg tcctcagcgc cctcaatgct gccctccgac
     2821 atctccgatt tcacgggtag ggaacagttc atggcacggt cgcgccagta cctcgtttca
     2881 gcctcgcata cacgcgcgac accgatactg gcgatcacgg gtggcggcgg ggtcggtaag
     2941 tcggccgcag ccgtgcacct ggcccaccag gtgacgaccg cgttccccga cggtgtgctc
     3001 tacgcggacc tcggcggctc gtccgaccgg gccgatgcct cggagatcct cctgcagttc
     3061 ctccgcgccc ttggcgtacc cgacgagagg attcctgcca ggactgcgga gcgcgccgcg
     3121 ctgtatcgca cgacggccac cggtaaacgc gtgctcgtcc tgctcgacga cgccgtcgac
     3181 gagcgtcagg tggagccatt gctacccggg caccccagca gtggcgtggt catcaccagc
     3241 agagcgaggc ttgtcggcct gccgggagcc cgcctgttct ccatggaagc actggatagg
     3301 cacgacgcgc tgcgactgct cggcaccctg gtcgggcggg agcgggttgc cgtcgaaccc
     3361 aaagccgccc aggagctggt ggaaaggtgc gacgcgcttc ccctggcact gcggatcgcc
     3421 gccacgcgcc tcactgtccg gccacattgg actattgagc agatcgtgcg actgctcgcc
     3481 gacggaacga ggcggctgga cgtgctggcg cacggcggtc tcagcgtccg cgcgagcatc
     3541 gaggtgacgt accgtcggct cgacgcccag gccaaacggc tcttgctgag gctcgcctcg
     3601 ctggaggatt cggagttcga cgctggtaca gcgacatcgc tgctgggact cgatgagctc
     3661 gaagcgacga acatcctcga aactctggtg gacgcctacc tggtgcgtgt cgtacgaggt
     3721 accgctgggg agacaaggta ccggctctct ggactggtca gagcgttcgc cgccgagccc
     3781 cagtcggtgc agggtagggc ggcccgacaa gctcgtgacc ctgcagcgta gcaggagatg
     3841 ccgacgattg cggaacgata ccgcttcaaa ggaccgaccc gctgtagtgt aggcatggtc
     3901 gcgaacagaa acttgtggga gaccggatat cttcctgccg gtggtgccga tggcttggag
     3961 cgtctgcgtg agctggtgaa cggcgggcta gacatcttgc gcgacaccgc cagccgccgc
     4021 gtcggacccg tggcgcccgg cggtccggcc ggggtggcgg cggccgctgc ggagctgttc
     4081 aggcggctgg atcccgcagg cggcaaccgc gatcgcgacg ccttcggcga cctcgtgcgt
     4141 gcctacgcga cctggtccgt cgacctcacc catcacgccg ccgtggcccg tatgcagtgc
     4201 gcgccggctg tcgaggccgc agcggccgac ctcatcgcga ccgtcacgaa ccagtcgctg
     4261 catgcctggg agagcggccc gttcgcgctg gaactggagc gctggctcgt cagctggctc
     4321 gtcgcgctcg tgggctacga tcccggggct ggcggaacgt tcactgcggg cggcagcgtc
     4381 tccaacctca tggctctgct gctggcccgc gaccacaacc tgtcgcgtcg agtgggtgcc
     4441 gcgactttcc gcgacggagt caccgggttg ggcgtgcgcc cggtcgtgct ctgcactgcg
     4501 gccacccact tctcgatcgc gcggtcggtc gggatcgtgg ggctgggttc cggttcgatc
     4561 ctgcgggtgc ccgacgacga gaagggccgg atgatccctg atgcggcgga ccggatgctg
     4621 gcggagctcc cggacgaccg gcccccggtc gcactggtgg cctgcgcggg tacgacggac
     4681 ttcggcgaag tcgatcccct gcccgaactg gcggccatcg cccgcaggca tggcgtctgg
     4741 ctgcacgcgg acgccgcgta cgggggcggt gcactattct ctcagcggct gaagacaatg
     4801 ctgaccggca tcgaacaagt cgactcgatc acgctggacc tgcacaagtt cggctggacg
     4861 cctgcatcgt caggcgtgtt cctggtgcgc cgtgcggagt tcctcgactc ctggtcgggg
     4921 caaacgacga cgctcaacgc cgatgacgac aaggtcgcag gctattacgg ccgctacgag
     4981 tcctccttgc aggccacccg ccgcgtcgac gctctcaaga ttgccacggt actgctcacc
     5041 ttgggagaac agggcctggg cgacatggtc gaagcctgcc atcgacaggc tctgcacgcc
     5101 gcgcggcgca tcctcggcga gcctcgcctc gaactggcgg ccgaaccggc gctcagcacg
     5161 gtcgtcttcc gctacctgcc tgaatccgcg ggtgacgcgg acgcgttcaa cggcgagcta
     5221 cggcgacgcc ttatggccga gggaaaggtg ctcatggcca ggacacgcgt gccacgtccc
     5281 gatggagacc cggtgttcct gaagctcatg ctgctcaacc cggagacgac cagtgaccag
     5341 atcgacgaga tcgtcgcgga tgtgctcgcc gtcgcggcac gaatggagac cgccgtcccc
     5401 gcgtagccag cgttgcgaca gttttctcaa ggacagcttg cccagacagg aggtggttca
     5461 gacatgagtt cgcaggtttc ggatggagtt gagctcatgt cctcctaccg taaggaccca
     5521 gttagagagt cgatgacagt gctgcccgcg gtgttcgccc tgccgctgac cctgctcacc
     5581 gggaaaccac acgccgggca gcggccgttc cgcatcaccc ccacagttca cctggtgaac
     5641 gccatgctgt cggtgtcctc cggtctcgcg ctgtcggccg gagcgctcgc ctggacggga
     5701 tggtggctgt tgctgctgtt accaggatgg gccatgacgc tgcacggcat ccgcaacctg
     5761 cgcatgatga tctttcacca gtgtgcgcac cggaacatgt ggggacgccg gaagctcgac
     5821 gcacttctgg gccgtgtcct gtcggcactg ctgctgatcc agcattacga cacgtacagc
     5881 gccgagcacg tgcgcgacca ccacgcgctg caccacatga ccttgcgcga ccccacggtg
     5941 caggccttcc tgctgaccct gcggctgaga cccggcatga cccgccgaca gatgtggcgt
     6001 atggcgatgg ctaagacatt ctccccgggc ttccacgctc gcttcttcgt cgcccggatc
     6061 tgctcctact gcagcgcggc gacccgcatc gaaaggactg tcttcctctg ctccgtactc
     6121 acgctggcgg cactggtgtc gtggctgggg ctgtggacat tcgtcctggt cgcgtggctg
     6181 ccacccggga cggtgttctt ccagatgagc aacgtgctgc ggctctgcgt caagcacacc
     6241 ttccccgccg ccggggtgac cgagcggcgc ggcagggact acttcgccgg tctgaccaac
     6301 gccatcttcc tcggtgaggc ggcgcccgcc cccggcctgg cgtggccgaa acggatgcgc
     6361 gcctgggcgc ggtggtggct gcgtatggcg ttcgtccatt ttccggcgcg ctacctcgtg
     6421 ctgaccggcg acacggtctg tcacgacttc catcaccggt atccgatgag caacaactgg
     6481 gcgaactaca tcttcgcgag ggaggccgac ttcaccaagg gacatcccgg ttggccgccc
     6541 taccggcacg tgtggggcct cgctgcagga gtcaacgtgg tgttcgactc gctcgccgca
     6601 gccgatgcga ccgaatacga cccggaacgc ctgaccgcgg tgaacaggcg cgacctgttc
     6661 ctagccttcg acgactgacc gactgcggca tgacgccccc aaggaggacg atatgactgg
     6721 cgaggatagg caaggggcgc ccctggtgat cctcggggtg gcggagagcg acgcgcacgc
     6781 ggtggcgaac cgccttatcg agatgtactt gcgggcgcag gggtatctgg tggtcaacct
     6841 cggagtctgc accccgctca ccgacttcgc cgacgcgctg gccgcgcacc cagaggcggt
     6901 ggccgtcctg atcgggagcc tcaacgggca cgcctacgac gacctgcgtg acctgccggc
     6961 actgcgcgcc gccggctggc tggaccgtcc agtcgtcgtg gggggcaacc tgtcggtcga
     7021 cggcgcggag gggcatgcag ggctccacgc gctcggtgtc gatcacgtgg cccgcgacga
     7081 gcacgaactg ctggctctgc tcgatcagct gtgttcgccg gtggctcggt ccctgggtga
     7141 ggggcgatga cgggtctgtg ggaaggtcta gacctcccgg ccgagttggt gcggaacctg
     7201 cccgctgaag cagacacact ggcccacgca cgagccatcc aactgcgtcc cgtggatgtg
     7261 ctgcgggcag ccgacgcgtc cggccggccg gtgatccagc cgcgctgcgg ggtcggtgga
     7321 caccagcaga tggtggacct gctccgcgac ctggagcgag tggattccgc gatcctgtcg
     7381 gtcaccatcg actcctacac caggctcggc cggttcgggt cggccgagcg gctactccac
     7441 gaccggcccg ccgacctcaa cggatacccg ctggtggcgc acgggtggca acgcggccgg
     7501 gacctggtct cggccgtcga gactccgctg gaggtgcggc acgggtcgcc cgacgcgcgg
     7561 cgtctgttcg cggtcagcgt cgcctcggga atcctgtcct tcgagggcgg cggccttggg
     7621 tacaacctgc cgtactcgaa gaacgtgcct ttgagcacgt cgctggacgc gtggcgccgt
     7681 gtcgacgcct cgtgcggctt gctctcgcgc gaaggtgtca tcgtggacag ggagctgttc
     7741 ggaacgctga cggccgtgct ggtgccgccc tcgatcagcc tggcggtcac catgctggag
     7801 gcccgcgccg ccgctgggga aggcgtcacc tgcctctcga tcgcctatcc gcaaggcggc
     7861 caggtgcacc aagacgtcgc ggcgctgcgg gcgatccgcc cgctcgcccg ccggtacgtg
     7921 agcgcggagg tcgaggtcta cccggtactc cacgagttca tgggtgcctt cccccgtacg
     7981 acgacggccg cggacgcgct gattctccac ggtggactcg tcgccaggct cggcggggcg
     8041 acgaagatcg tcagcaagac ctcgcaggag gcgcgacgga ttccggacgt ggtggcgaac
     8101 gctcacggtg tccgtaccgc ggcgctcggt gcgtcgagcc tgttcgactt cgtcgaagtc
     8161 gacgaggcgc gtgtcgctga ggagcagtac tggatcgagc gcgaggtcgc cgagttggtc
     8221 gagcccgtcc tggatgacgg cgatctgacc ggagccatcg agcgggcttt ccgcgcgggg
     8281 cggctagacg taccgttcag tgccagcctc cacgccaggt cggacgtggt gccgtgccgc
     8341 gaccggtacg gcgcgatccg gtacggcacc cttggagcac tgccattctc cggcgcggcc
     8401 ttgcgtcgga acgcggcctc gctggccgag agcccggagc cccgcgacgg gcgttcccag
     8461 tcaccgattg agcgggtgtc cgccgatatc aactacttcg tcaacctgga cggcacccgc
     8521 cccaggccgt tgcccgccgt cccttcccca ccgttcgcga gaaagtcacg atgaaggtgc
     8581 catcgactcc gaaaaacgac caggcgatct ctccggcgga gcgcgaccgc ctggtgcgtg
     8641 aggcgcaccg tgcccacgtg ttccagccct ggtcggcaca ggcgcatgtc gctccgttcc
     8701 ccgtggccgg ggcggaaggc cggtacttct gggatcacca gggcaaccgg tatctcgact
     8761 tctcctccca gttcgtcaac ctcaacattg ggcacgccca tccgaaggtc gtcgccgcga
     8821 tcaaggaaca ggccgaacgg ttgtgcacca tcgcgccgca cttcgccaac gagcagcgga
     8881 gcgaggcggc tcgccttata gcggagctga cgccgggaga cctcaccaag atcttcttca
     8941 cgagcggtgg agcggaggcc aatgagcacg cggttcgcat gacgaggttg ttcacggggc
     9001 ggcacaaggt gctttccgcc taccgttcct accacggtgc cacctccacg gcgatccacc
     9061 tcaccggcga ccccaggcgg tggcccaacg acaccggggc ggctggcgtc gtgcacttcg
     9121 tcccgcccta cctctaccgc tcggccttcg acgcccgcac ggaggcggag gagtgccgaa
     9181 gagcgctcga ccatctcgag cagatgatct gtttcgaggg gccgcggacg atcgcggcgg
     9241 tgatcctgga accagtcatc ggcacgggtg gcgtgctcgt cccgcctgcc ggatacctgc
     9301 cgggcgtacg cgccctgtgc gacgagcacg gcatcgcgct gatcgtcgac gaggtcatga
     9361 ccggcttcgg gcgtaccggc aggtggttcg gcgtcgatca ctgggatgtc gttcccgacc
     9421 tgctgacctt ctcgaaggga gtcaactcgg gctacgtgcc gctcggcggg gtggctatca
     9481 cggcgcgtat cgcggacttt tttgccgacc ggccctaccc cggtgggctc acctactccg
     9541 gccacccgct ggcgtgtgcg gccgcggtcg cagccacgcg ggcgatggcc gacgagcggg
     9601 tagtcgagca cgcctcctgg ctgggcgagc aggtgctggg cccggggttg cgggatatcg
     9661 ccgaggcaca tccgtgcgtg ggcgaggttc gcgggctcgg tgtcatgtgg gccatcgagc
     9721 tcgttcgcga ccgcgatacg cgggaaatgc tggtgcccta cgcggccacg ggtaccgaca
     9781 cggctccggt cgacgaggtc atggccgagt gccagcgccg cgggctgtgg cccttcgcca
     9841 acttcaaccg cgtgcacgtt cttccgccgt gcaacaccac ggaagacgag gcacggaagg
     9901 gcctcggcat gctcgacgag gcactgacgg tggccgactc ccgggtgacg gcgggatcgc
     9961 gacgcggccg tccgcgggga ccgagaacag gagacatcga atgattatct gtggtctcaa
    10021 gctgacccac gacggggcgg tcgcgctgct cgacggcgac cggttggtgt tcagtgtgga
    10081 aatcgagaaa cttgcgaaca accggcggta cagcgacatg cctgatctac gggtgattcc
    10141 ggagatcctc gcgtcgttcg gctgccgggt cgccgacgtc gacgagtggg tgatcgacgg
    10201 atgggatggc gacgtgagca gggacctcga gctcgccgac catgggaggg cgatcacgct
    10261 caccgtcggc ccgtaccgcg agtcggccag cagcccctcg ctgacgagcc cgagcctcac
    10321 gggccagttc accatcgacg gaaaagaatt ggtctatacc agttatccac atgcggccgg
    10381 ccacctcgcc ggaacctact gttcgagtcc cttcgccgac cggggtgaac cgtccttcgt
    10441 gctgatctgg gacggcggcc tattccccag gctctactgg gtcgacccgg accgcggtgt
    10501 ggacaacgga ggcgagctct ttccgttgat cgggcacgcg tacgccatgg cgggactgag
    10561 tttcggtccc ttccgcggct tgcctcagaa gaccaagacg gacgagctgt ctgtggccgg
    10621 caagctcatg gcctacatcg cgctgggaaa ggccgatacg ccggtgatcg acgtgctgcg
    10681 cgagacgttt cacgaaacct tcgaaagcaa gacaccggag gcggtgcgct accgcgaaac
    10741 gatcgggggt ttcggcagcc tcttcgaacc gtcccgcgcg ccggtgaacg cgttcctcgg
    10801 caaagtgcga gaccgcgttg aggccctcgg tgtcccggac gaggacgtgc tggcgagctt
    10861 tcaccagttc ctggaggagc tgctggtgga gcggatcgag gcgaaggtgc gcgagtggaa
    10921 gggggatggg ccgtggaacc tgtgtttcgc cggaggttgt gcgctgaaca tcaactggaa
    10981 cagcgcgctg cgcgcccgtt ccctgttcgg tgaaatgtgg gttccgccgt ttcctaacga
    11041 ctccggatcg gcgctcggcg tcgcgacgct gggcatgatc cagcaccgcg gaatcggtcc
    11101 gatcacctgg catccccagt cagggtcggc tctggggccg gtcacggagg tgccatgcgg
    11161 ctggacctcc cgtcgcgccg cggcggcgga ggtggcccgg ttgctgcacg agtcgggtga
    11221 gcccgtagtc gtgctcgagg gcagggccga gctcggcccg cgggcgctcg gcggccgcag
    11281 catcatcgcg ccagcagcgg acccggcgat gaaggacagg ctcaacgaca tcaagaaccg
    11341 cgagtcctac cgtcccgtgg cgccgatctg cctggtcgag gaggcgccga agatcttcga
    11401 cccgggcacg cccgatccgt acatgttgtt cgaccacgat gtccgtgaag gctgggcgtc
    11461 gcgcatcccg gccgtgatcc acctcgacgg aacggcccgg ctgcagaccg tctcctccga
    11521 cgacttcccc gaaatcgccg ccctgctcgc cgagtaccac aagctctcgg ggattcccgt
    11581 gctgtgcaac acgagcgcga acttcaacgg cagcggtttc tttcccgacg tcgcctcagc
    11641 gatcgaatgg ggccgggtag cccgggtctg gagcgagggc gtcctgtacg agcggaccgg
    11701 gagttgagtg gaggttcagc gtatgcgttt gaccaagccg cagctcgacc ggtaccaccg
    11761 cgacggcttc ctcgaactcg accgcgcgtt gagcgcggag gagacacagg ttctccgcga
    11821 ggcgttcgcc cgggactgcg acgtgccggg gccccatcgg gtgctggagg acgaccggac
    11881 ggtccgggcc gtgtacgcct cgcaccagcg gcagcgcgag ttcgccgccc tcgtgcgcga
    11941 ccggcgtcta ctggcccccg cacgccagct gctgggagac caggtctacg tctaccagtt
    12001 aaagatcaac tccaagtcgc cgttcaccgg ggagggctgg tcctggcacc aggactaccc
    12061 cgcctggcgc atcgccgaca gccttgccga acctcggcag gtcaacgtgg cggtgttcct
    12121 cgacgacgtc gacgagttta acggcccagt cgtgttcgtg cccggttcgc accgcttcgg
    12181 tccgctccac ctcgaccgca cgcccgacgc gaagtccgat cagcacatcg accccgatga
    12241 catcgcgctg accagagagc agctcgcgaa actcgtcgac gcgggcgcga tggtggcccc
    12301 caaggggcct gcgggcacag tcgtattctt ctcctcggaa gtcgtgcacg gctcaggcgt
    12361 caacatctcg ccgtaccccc gtcacctact gatcgtgacc tacaacgacg tcagcaatcc
    12421 gccgagctgg cgtggcgaac cacggcccgg ttacgtcgtc tgccgggata acgatccgct
    12481 cacgtacctc gacgatccgc tcgggccgtg gaccgtgcgc cgtgccgcca cggttccggt
    12541 ctccgaggac atccgatagt gcggtgatat tcctcaaatg gaagccgtcg gcatggtcga
    12601 atcagtgaag ccgcagggtg ccaacgtatc ccgccgtaac gagcgccggt atcgcccccg
    12661 tgggaggaag ccagcatgac agaccgagtg acggcccggt acctcgaccg gtgcctggcc
    12721 ggcgaccggg gcctcgccgc cgcgatgacg gccgctaggc ggtggctgcc aggcagcctc
    12781 gacgagcgtt ggggcgatcg gctgatgtcc cgccccgcat ttgtggacga cgccgggatc
    12841 ttctccttcg cccacgacct cgaagcactc ttcgggcttc tcgtcgcgct gcccagccga
    12901 ctcttcgacg gcgacctcgg ccgattctgc gaggcggtgg gcatcaccgc gcgccaggcc
    12961 gccttgatgg cgcggctacc ggatccggca ccctgctacg gcagggctga cgcctaccac
    13021 gacggcaccg gtctaaagct gctggagttc aacgtgggta gcgagatcgg cggtatcgac
    13081 accgcccacg tcgccctggc cctcacccag gtcgacgcct tccgggcctt tgccgaggag
    13141 aacgagttgg cctacgtcga caccggtaag cgggtgaccg acgccatcag ggccgcggcc
    13201 gaaccgctga ccggcggcac cgatcccgtc gtggcgctgg tcgaacccga cggcctcatg
    13261 cacgagtatc tcgaggagga ccgctccttc cagcagatgc tgtcggacct cggcctcgac
    13321 acgttactcg gcgaagtcgg cgagctgcag caccgagccg gccgcctgca tctgcacgga
    13381 aggccggtgg acatcgtact gcggtacttc actgagaagg agatcgccgg tcagaccgcg
    13441 agcgagcggg ccgtcgagat ggtggcgcgg gcgcatgagg aaggtcgggt cgtactgtgg
    13501 acgacaatgc gcagcaagct cgctgccagc aaagcctgtt tcggcttgct gtcggactcg
    13561 cgctgtcgcg aagcgttctc cgcggacgag atcgcgctga tcgagcgggt ccttccctgg
    13621 acccggatcc tggacgacgt cgagaccgag gtggaagggc agaccgtcag gctgctcgag
    13681 tactgccgcg aggcccgcac cggtctcctc attaaaccgc acctcgggca tgatggcgtc
    13741 ggcattgtgg cgggctggcg cgtcacggac gcggagtggc gcgacgccct cgagtccgcc
    13801 gccgccgcgg gcgcgatcgt gcaacgccgg gtgatctccc ggccggagcc gatgattgat
    13861 cccgaaagcg gcgaggtgga gcactggggg tgcacctgga gcgtgttcgt cgtgccggac
    13921 ggatacgctg gcacgaccat gcggacggtc acgctggaca acaggtcgga aagacgctgc
    13981 ctggccccca tcttccaata tcccgcgagc acatatgggg gagcgcgatg aagtacacgc
    14041 ggtactgccg ttcgatgctg tcgaccccgg cgctgcagac ggaccgcttt cgcaagagcc
    14101 acgaagccga cgccgacatc tgcatggtgg acttggaaga ttccattccg ccgtgggata
    14161 aggacaccgc gcggaacctc gcggcgaggt tcttcgtccc cccggccccc gccaggtgcg
    14221 cgatacggat caacacactc acgacgccgg acgggctgcg cgatctgttg gcgattcgtg
    14281 actatccgac aaaacccgcg atcgtggtgg ttcccatggt ggagtcgcca cgtgacatcg
    14341 aggtcgcgga gagcgtcctc gtgcggacct gccccgacgt cgagttcctc gccgtggtgg
    14401 agaccccgcg tggcgtggag aacgccaacg cgatagccgc cgcgtcaccg cggctgcggg
    14461 cgctcatctt cggttccgcg gactactcgt tcttggccgg cgtgcgcctg gcctgggaca
    14521 ccctggtcca cgcgcgggcg cggctggtga acgccgcgcg agccgctggc atcgaagtca
    14581 tagacgcgcc caccttcgag atctcggagc acgcgacgat caaggaagac gccgtccgtg
    14641 cgcacgacct gggcttcagt ggcaagattg ccatccaccc gcgacaggta ccggtgatca
    14701 acgaggcgtt ctcgccggac accgcgacgc tcgagaaggc ccggcgcatc gtggccgcag
    14761 ggcaggagaa cggccggaag atcgcggtgg tcgacggcgc gatggtggga attccgtttt
    14821 tcgaggcgtc tcagcacctg atcgaggaat tcggcgacct gcttcattcc tgaccgcaag
    14881 gagagatatg agcacggata ccggcgctct ggagcgtgtt ctcggcgcgc accgataccg
    14941 caacaccgaa aagatgctgc gaatgtccga ccccgtgtgg ctcgccgcgg ccagcgaggg
    15001 tctgataaac ctcaacgtcg aggcggcgtc aaacaacaag atgatcattc ccgagagcgg
    15061 gcacgagttt atcaacctct gctccagcgc ctacctcgga ctgaacttcc atcccaaggt
    15121 cattgaaggt gccatcgacg tcctacggga ggccggcacc accggcttgt tgacgtcgaa
    15181 cgcgcggatt cggcaccgga cgctgggccg cctggaggag gagctcggcg agctgttccg
    15241 ggcgacagct ctggtcggcg tctcgtgcac ggcgctcagc ttcggcatac ttccgctggt
    15301 cgccgcagga tatctcgcag aaggcggggc gcgcgtgatg gtctacgacc gattctgcca
    15361 tttctcgatg gcttatgtca agccgatcac ggccgacgag tccctggtgc tgacggctcc
    15421 ccacaacgac ctaaactatc tcgaagacgt gtgcaagaaa tacccgcgag tggcttacat
    15481 cgccgacggt gcgtactcca tgggtggcgc cgcggcgctg gacgggctcc aagagctcca
    15541 ggaccgctat ggattgttcc tgtacctcga cgattcgcac tcgttgtcta tcaccgggga
    15601 gcacggcgaa ggtttcaccc gatctcagat cgagatgaac cccctttcga tcattgtctc
    15661 gaccctgaac aagggattcg gctccaacgg tggcgtcgcg atgctgggac ggccggaact
    15721 ctatcccttc ctcactcgcc acggagggcc gatcggctgg tcgcagaaca tcgaagtgac
    15781 cagtgtgggc gcgtcactgg ccagcgccga gatccaccgc tcgtccgaac tgggtgagct
    15841 ccagcacaaa ctccaggaga acatcgacta tttcgaccag cggtatccca ccaagttcgc
    15901 cggtaacaac ctgcccgtgc gcctcgtccc ggtgggcgat gccgaccgct ccgtccgcct
    15961 gtccggcgaa ctgttccggc gcgggtacta cagctcggcg gtcttcttcc cgatcgtacc
    16021 gcgtggcaaa gcggccctgc gtgtgatgat ccgagcggac atcagcaagg acgcactggg
    16081 cgggttcatc gacacggtcg aggagctcac cgctgactcc gacgccgacg aggctcccgc
    16141 ccatggatga ggggccgacc ggatatcggc gcgtcggtgt gcagcggtac cgggagacgg
    16201 taggcttcta ctacgaggag ttcacggtgg gcgacgtttt cgagcaccgc cccgggcgca
    16261 ccatcactga gatggacaac gtgctcatga gcatgctcgg tatgaatgcc tcaccgctgc
    16321 acatcgacgc cgcctacatg aagcacaccc gctgggagca gcctatcgtc tccagcctgg
    16381 tgaccctggg aatagtcggt ggaatgacag cgcgcagcac cagcggccgc gctgtcgcca
    16441 acctgggatg ggacaacatc cggttgcttt ccccggtcct cgcaggggac actctctatg
    16501 cggaaaccga aatcatgatg aaacgcccgt cgcaaagcta tacagatcac gggattgtgg
    16561 gttgccggac attgggtatt aagtcgactg gggaaaaggt catttctttc gaccggtcgt
    16621 ttctggtgcc catgcgtgaa cactcccggg acgccgaggt tggttactga ggtcgcaaga
    16681 cgaggagtgc ccactgggcg gattacgatc tcagggctct tgtgagcttg cggtagtttg
    16741 ttgactctgg cggctggtgg taggccgtga tttgacaggg tttcgcggtt ggttgagggt
    16801 gtgcgctatg acccgagttg ggccaattta gtgcgtagcg gcgcgggtct tgattgcgtc
    16861 gaggatctgg tggatgtcgt cgggtagcgg gtcggctgcc gtgatcacgt ggtcgccggt
    16921 ctggatgtgg atggtgcggt agcggcggat ggtcttgacg aacttcttga tggaccagcc
    16981 ggtggtgtcc tcgatccagc gggagacggc cagggcggcg aatacgatcg tcaggtgcgc
    17041 ttcgatcgac tccttggtgt ggtggaagat cgggcgtgcg gctaggtcgg acttggccat
    17101 gcggaagctt ttctcgatct ggaacagctg gcggtaggcg ccgatgacct gttcgggtgt
    17161 ggggtcagcg atgttggtga cgtagccctt catcccggcc aacgcgcggg tcttggcctc
    17221 caggtcgcgg ttgacggtct tggtggcgtc ggtgagcttg acgaatcgat tgcgcttgag
    17281 ggcggttttg ccggccacgg tctgctcggc cttgcggatc tgttcgtcga tgcccttgag
    17341 cgtgcggcgt gcccggtcgt gcttgtactg gtagtaccgc atctggtctt tgcgcttgtc
    17401 ctttgtgccg gctggccagg gttggacgaa cacgtgccca tccgggatcg ctttgtcggg
    17461 gtgctcacgg cgccactcgt ccacgacgta cgggacgtcg gggatcttca tcccgaggat
    17521 gaacgagagc ccggcggcct cgatgtcttt catgttgttc tcggagatca ttccggcatc
    17581 ggcgacgatg accacgtcgt gcagaccgtg ggcggccatg aacgcggtga tcgtgggcag
    17641 catcgtggtg atctcggcct tgttgccctc gaacgcgtgg accatgagtg gaacccggcc
    17701 gcgtcggtga gcaggcccac ggtgatctgc ggttccaggc ggcgttcctt ggagaacccg
    17761 gactcacgga acccgtcgcc ggtgtcggtc tcgaagtaca aagtcgtcac gtcgtagagc
    17821 acatacgtcg ctggtcccag gccgacatgg tgggcgcaca gcgccgccag ccgctcccgc
    17881 cacgcatcgg cggcgtacaa gggaagacgg cgcttgagcg tgcggtagga caccggcgcg
    17941 atgcccgcct cctccaacac ccgcagcgcg tcgagcttgc tggacggctc gatgatccgc
    18001 gccagcacca actgccggaa cacctcatcg ccgtcggcgg cagcatcgaa cccgagcacc
    18061 tcatacgccg acgacagggc gtcccacagg tgccccatcc gggaggcggt gatcggcaac
    18121 ggtccgcccg cctccggtga ggcgtccaga ctcagctcga gctcgccctg cccggccgtc
    18181 atccgttgcc gggcgacggt cctgagcagc tctaactcga catcgtcatg ggcggaaccg
    18241 atgtgctcga tatcgcgcga gccctggcgc gaggagtgca cgatctgcac cgcacgagcc
    18301 ccggatgcgg tcttcacggt gcggatgtag gccaccagcc aacactagga ccccgactta
    18361 gtgcacaagc cccacccaac ccaccaacga actcccaggt cagcgagccg cgccgccgat
    18421 cagccccgat tcgtggccca agtcaggtct ccgccaggac cgatctcatg atcgaatggc
    18481 tcaaagaccc gaaacagtcg gtgatatcgc cctcgatgaa ccacaccgtc ccgtgccatt
    18541 ggtgatagat ctcctgcaag gcggtgtgac agccacggcc aggtcggaac ccgtgggaac
    18601 ggtcggagaa ctgcggctcg tagtacgcct ccaagatcag gcgcagcact tcttgcagca
    18661 gcttgtccga ccaggtcggc agccccagcg ggcgcttctt cgaggagttc ttcttctcga
    18721 tgtaggtgcg ccgcactggg gtccaccggt agcgctcctg ccggagcacg gtgatgattg
    18781 cctcgatctt gccgaggttc atgccgtcca cggtctcgct ggtgacccca ggagtcatcg
    18841 cccccttgtt gcgatagagc ttcccatagg caagcaggaa cagatccggg ttgaacaagc
    18901 accggtagac ccgttccaac ggcagtcctc tcctgccgcg ttcacgaatg atctccaata
    18961 cggttgcggc gtctcgcatc tcgcgtacct caccgtcctt gttgaccttg agcacctggg
    19021 tcccttcgcc cgtgtggacg gctctcccgt cctccctggc agggcgtgac tcctgcgact
    19081 actacggacc ctccgtggcc ctagggctcg cgccccgtag gccatctcga attcctcaat
    19141 gcgccagacg tatcgagcgt gacgtaggcg tcccggtccg tccccttgaa cgggctcact
    19201 gcccgtcgcc cgccgaccgg aagggttcag agcgacgaaa gtcggaatcg cccctatgct
    19261 ggcggccccg acaacagacg ccgtgtcggg aggtgtgaac gtttgcaccg ctgggaactg
    19321 ggtttcaagc agtgtggcct tcgccgtatc acgcgggcct tgcacggcca taccttcggc
    19381 gtcttcgcgg catcccgcgc tttcccgcca tgctcttgtc ccctcccggt ttcccgttca
    19441 ggtaaggcgg gtggcccaga ggtcacctcc tcccgaacct ctgccccctg cgggggcgat
    19501 ccagcgccga gttagacggc gcaccctttc aacgcaacgg gctctccacg gtttctgtcg
    19561 ttaggcgtgg ttcgtgcagg gccacgggtt ggggatgctg cgtcggcggt accgggtgac
    19621 cggtgtcgcc gcgatgttgc gcagttcgat cccgtcggcc gcgatcggcc gccaccctgt
    19681 tggggttcgt agccagcggt ggacgtcctt ccatctccag cgccgtttgg tcttgaccca
    19741 tcggacgatt cgccaccaga tgaagtaggc aagccggtcg aaggtgtgct tggccacggc
    19801 gtgtcggaag tattcagccc agccgcgtgt gatccgattg atccggatca acacggctcg
    19861 taggtcctgc tgtgatgtcc tgcgcgtcag ggcacggatt ctcgctttca gtgatcggac
    19921 gggccgatcg ccgacgaaag tgtagagccg ccactgatcg cgggtccctt tcttgattct
    19981 ccaccggatg cggaaaccca ggaaatcgaa cccgtcgcgt atgtgcacga tccgagtctt
    20041 ggtcggcgac aaacgcagac ccatcggagc gaacacctgc gcgatttcct cgcgcaacgc
    20101 caccacgtgg tccctggtgc cgaacaccat gacgacgaaa tcgtccgcat accggacgag
    20161 tcgccaggtc ggcagaccca ggcgccgatg gcggtgacgc cggttttctg tcgacatcca
    20221 accccctggc cgccagtcgc ggtgcatgta ctcgtccagc accgacaacg cgatattggc
    20281 caaaagcgga gagaggatgc ccccttgcgg cgtcccggtc ggtgtgtccc gttcctcgcc
    20341 gagctcggtc aggaccccgg ccttgaggaa cgatttcacc agcgtaagca cacgcttgtc
    20401 cgtcacccgt gcccgcacgc ggtccatcag ggccacgtgg tcgatggtgt cgaaacaagc
    20461 ctcgatgtcg gcatccaaaa cccattcgta gccgcggctc ccgaacagat ggatatcggc
    20521 gatcgcatca tgtgcccgcc gtttgggccg gaacccgaac gagaccggat gaaaatcagc
    20581 ctcaaaaatc ggttccagga ccagtttcag ggcggcctgc acaacgcggt cgatgacagt
    20641 aggaatgccc aacctgcgga ctttccccga cccgaccggc ttgggaatca accgttcccg
    20701 caccggctgc ggccgaaacg aaccgtcttt aaccacgatg cgaatgccac ccagaaactc
    20761 cagggcgccg atgtcccgct cgatccgggc gacggtgacg ccgtccgaac cagcagtacg
    20821 tgccccggca ttcgatgcga cccgttccca cgccacacgc agggttgccg ggtcgtgcac
    20881 gaggttgaac aggtcatcga accgtcggcc aggatcggcc gacgcccaac gatgaagctt
    20941 ggcctgcatt tccgataccc gacggaacga cccgacgtcg ggttgttcca gagcgccgct
    21001 attcaacggc gcatctttcg gcaatgcagc atcccttctt ctcgaaaccg ctgccgtcct
    21061 tccccctgtg accggctttc ccggcctccg agtactacga cggctccgcc ctgcccggcg
    21121 tgttcagcag acggtgtgcc tatcccgacg tgcgagctgg atgcccacca gtcgggaacc
    21181 atcaccagac agttcccgtg ttcacatgct gatcgcttgc cgaaggaggc atctgacttt
    21241 gttcccgcga tatcgccgtg actacgccgc agaccttcac cacggcctcc ctgcgaaggt
    21301 gagaatcccc gctcaggagt tccctgcctc atccaagaaa cgggtgcgca tcgcgaccgg
    21361 ccatccacca ggtttcagcc ggtgactact taggaaacgt aacacgccag ttcctcgcgt
    21421 atacctcttc gactcgtttg ccggacccgc accatccggc agttctggca cgtcccggtt
    21481 ttgtcggggc cgcttgccac cctcaccggc acctcccagt tcgggctgcc cccaacttca
    21541 acaggccgct gcgacggccc gcaggagaag gtcttccacc tcctcgcgac acaacagcgc
    21601 tttcacggcg cactctcgcc ggtggtcaac cctttcgcat acaacgacaa cacaatctca
    21661 tccacactgc ccaacctgcg ctgccgcttc ttcaccacca ctggctcgaa gctgccctcc
    21721 cgatcgcgcg gcacccgcac ctcaacctcg ccctcggcgt ccgagaccac ggtcttggcg
    21781 cgggaaccgt tgcgcacgtt cgtgccctca cggccgggct gatcagcgtg cttggcatgc
    21841 cccaggtgct cggtcatctc cgcgtccagc gcggatctcc agcaccgtct tcgtcagctg
    21901 ccccagcagc ccgtccgggc cggtcaaggc catgccctgc tcctgcgcct gcttgatcat
    21961 ctccgcggcc agccgctgct gcgcaccggc ggatcagtcg cctcggcctg cttcttcgat
    22021 gcctcactcg tcacagcatc aacagtcatc ccactccgtg cccatcccgc ctgacctcag
    22081 cccggcgtgt cgggccgaac ccaccgatct tgaaacagtc cctggtcaca caacgtgatc
    22141 agagggttac atacgttcag gtgcggtaat gccgaggagc ccgagtccgt ggttaagcgt
    22201 gcgggcggtg agctggcata gcgcgagtcg gttgctgcga gtaggttcgc tagccttcag
    22261 cacgaggcag ttttcgtaga aggccgtgaa gtcgcgggcg aggtcgtaga ggtatccgca
    22321 gaggcggtgc ggttcgaggc ttgcgctgac ttcggccaag atgctggcgt aggcgtcaag
    22381 ttccagcgcg agggcgcgtt cagcgggttc gagtgggatg ttcgggtcga tggtgacgtc
    22441 ggggtcgtcc acgttgcgga gcatggaccg gatgcgggta tgggcgtact ggaggtagac
    22501 gccggtgttg ccggtgaagg agaccatgcg gttgacgtcg aaggcgtaat ccttgaccc
//
