LOCUS       NZ_CP076538            24058 bp    DNA     circular CON 16-DEC-2024
DEFINITION  Amycolatopsis aidingensis strain YIM 96748 chromosome, complete
            genome.
ACCESSION   NZ_CP076538
VERSION     NZ_CP076538.1
KEYWORDS    RefSeq.
SOURCE      Amycolatopsis aidingensis
  ORGANISM  Amycolatopsis aidingensis
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Pseudonocardiales; Pseudonocardiaceae; Amycolatopsis.
REFERENCE   1  (bases 1 to 7657695)
  AUTHORS   Li,R.
  TITLE     YIM 96748 draft genome
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 7657695)
  AUTHORS   Li,R.
  TITLE     Direct Submission
  JOURNAL   Submitted (08-JUN-2021) Yunnan University, Yunnan Institute of
            Microbiology, 121 Street, Yunnan 650000, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdevono v. 2.04
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 57.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_018885265.1-RS_2024_12_16
            Annotation Date                   :: 12/16/2024 14:59:15
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,118
            CDSs (total)                      :: 7,060
            Genes (coding)                    :: 6,941
            CDSs (with protein)               :: 6,941
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 44 of 119
            Pseudo Genes (incomplete)         :: 87 of 119
            Pseudo Genes (internal stop)      :: 2 of 119
            Pseudo Genes (multiple problems)  :: 13 of 119
            CRISPR Arrays                     :: 4
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 14:56:56
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 4950586
            Orig. end                         :: 4974644
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP076538.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..24058
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-i"
                     /region_number="26"
                     /rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..24058
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="lanthipeptide-class-i"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..24058
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:14058](+)"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..14058
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
     gene            complement(546..3131)
                     /locus_tag="KOI47_RS22640"
     CDS             complement(546..3131)
                     /EC_number="3.4.22.-"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012242.5"
                     /locus_tag="KOI47_RS22640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="caspase, EACC1-associated type"
                     /protein_id="WP_216206977.1"
                     /transl_table=11
                     /translation="MRKRALLIANQVYDDPRWTELPGAAGDAQQLAEVLGSRAIGEFDV
                     TVVPDKDARTVRRDIEEFFATAEQDDLLLLHMSCHGQVSATRELHFVARDTESAYLAAT
                     GISAQFVNDCIDESRARRTVLLLDCCFSGGYTRGLRQRGAQDEPVVGKRFQGHGKAVIT
                     ACSALQYAYESTVLSKPAGEPSVFTSAVIEGMSTGLADQDSDGQVSVEDLYRFVSMRVA
                     QQVANQKPELSMDRLSGTIYLARNIRALYQGHEAEPPIPAAIHRAVVNGEPWERFGATL
                     GLERLLDDVQTGNAAREALVPLTRDADEAVAERALAVWREKVGSAVPIAVGLAAERTVE
                     PTSHSVGIDFGTTNSVVAVLVDGRPVVVSNHLGVQLTPSVVTIQGSVVDVGAVAKDQAH
                     LRPSTTIAEVKRALGTGRSFVVADAEYSAENVAAFILDQLRRDAERYLGEPVGDAVITI
                     PAHYGVAERDALSRAARLAGLNAVRMINEPAAAALAAGSALGDKEQTILVFDLGGGTLD
                     VSVVELGEGVVEIRATSGDERLGGSDWDQRLLDWLVELAIEASGVDPRSDSTAAWRLRK
                     EAEKAKIELSHATTARVHLPYLAQADGLPVHLDVTLDRIAFERRTTDLVERCRRKVMDV
                     LRDVGISADEVDLVAAVGGSAALPAISRMLTSLGDSPIPLAEVDPYTAVAVGAALQGGV
                     LKGEVKDVLPLDVTPLSLGIATKGGVFTRLIERNTTLPTKRSEIFTTADDNQTTVAVQV
                     FQGDHDLAEDNKKVGVIELTDLPPVPQGVPQIEVLVDIDANGAVHVTVTDLGSGTRANK
                     RLSEATVMAGSEAAGAHAGLDEVMPTQLDEKDRPAPAEEWSAVVGNDLD"
     misc_feature    complement(1308..1310)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(3107..3442)
                     /locus_tag="KOI47_RS22645"
     CDS             complement(3107..3442)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="KOI47_RS22645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_216206980.1"
                     /transl_table=11
                     /translation="MDHLDAVGFGGPEFLRELSSEVVDPLWVVIDNGKGDSEHLVNDTG
                     EVAEATTENDVDPWSESRVASAARGSAAVLAPRLIARDNGSEQHGESVLAIADTLGAQI
                     CASGRCS"
     gene            3478..3711
                     /locus_tag="KOI47_RS22650"
     CDS             3478..3711
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="KOI47_RS22650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_216206983.1"
                     /transl_table=11
                     /translation="MVVSIVVAVATSPVLVSLAGVLREWVNRRNKRSMVIRDGDRSMEV
                     TGYDAQDIAVFLGKCQPSGQPEREPGAPDEPA"
     gene            complement(4211..4582)
                     /locus_tag="KOI47_RS22655"
     CDS             complement(4211..4582)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025569.5"
                     /locus_tag="KOI47_RS22655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="CPCC family cysteine-rich protein"
                     /protein_id="WP_216206987.1"
                     /transl_table=11
                     /translation="MEAEYPCPCCGHLMFTEPPGSHEICEVCFWEDDAVQLRWPDWSGG
                     ANTPALIDAQRAYAELGAMEFRFTGLVRTATPSEPVDDGWRPIDLAVDNVELQGVNSAP
                     WPTDHTSLYWWRPNYWRRS"
     gene            4705..4986
                     /locus_tag="KOI47_RS22660"
     CDS             4705..4986
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="KOI47_RS22660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_216206989.1"
                     /transl_table=11
                     /translation="METEDTNDKMEETFFADCQWELRAGAVAGQVLPDRHQRLLDLFAQ
                     PAAGGEVLRLRPSAVLTFVNGRVRDRHPRQAPLKAARRRARRTTATSA"
     gene            complement(5058..5541)
                     /locus_tag="KOI47_RS22665"
                     /pseudo=""
     CDS             complement(5058..5541)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005156674.1"
                     /locus_tag="KOI47_RS22665"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="DinB family protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MSAEDVIDQPVRVQFEAFLDEHRGALGRCFGQADRGAGVPIVGAV
                     PDYAAGPSQACDVHREGLVRRSPHLPVACRDRYPRDTGRVLHPR"
     gene            5637..5993
                     /locus_tag="KOI47_RS22670"
     CDS             5637..5993
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="KOI47_RS22670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_216206993.1"
                     /transl_table=11
                     /translation="MDTEREHDRWTATERECGYIRARLRLLTTAQGGRLTSICSGYRAH
                     WAFPPDVDQERHDAPLTLEQARTLAPGEDAMVRLHPLVPDLWPQVAVGLRLSMLEGARV
                     VGLADVMETVSPVP"
     gene            complement(7634..8797)
                     /locus_tag="KOI47_RS22675"
     CDS             complement(7634..8797)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="KOI47_RS22675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_216206995.1"
                     /transl_table=11
                     /translation="MGKRHRTNQPRRSLPGPARPPLRPHPSGDLALGPGSDLGTLLDAL
                     RLFGTPPHRIQALLDLVTQNARSDSSTLLSPATHFGITAVQRGSCPLDHDLLGQLQRSV
                     TAITRQVGSTPFVRLQLQLAPIVESCRRLLQRDHPGQHDELARLATHTYALAARLAFET
                     RDDQLATALYTDATAVAGQLKDRNHRATVRTSHTMVTLHATNDLDTARTIAHAATIDAH
                     QGSSYAVRARAHAVHAEICARAGQTREAGAALDRAWRTVEQLTSDDPHSGFNADRLHGF
                     DGLCALHAGDANRAHDSLAHSLNALKTSRDAVQRGIVSTDLALARLRLGDPACADLLHK
                     AIDITATTGGRVPAQRIRLARQHLRPWRTEHFLTELDDHIHDSLIGR"
     gene            complement(8992..9453)
                     /locus_tag="KOI47_RS22680"
     CDS             complement(8992..9453)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016701133.1"
                     /locus_tag="KOI47_RS22680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DNA-processing protein DprA"
                     /protein_id="WP_216206998.1"
                     /transl_table=11
                     /translation="MARHVTITGARSIPPQTEADLPGLFGDYLRPFADPDATFYLGGAA
                     GIDTAALDWLASHTQADLTVVVPCTVADQPAAAGEVIRRWQRAGRLTGVVELHADTLGA
                     SAYHARNRWMVDRSRFVIAFPHGTDPASGTWYTVNYAAEQDKPRLVVPV"
     misc_feature    9643..9658
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 21.35"
                     /tool="antismash"
     gene            9767..9919
                     /locus_tag="KOI47_RS36500"
     CDS             9767..9919
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LD_lanti_pre"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:TIGR04363.1"
                     /locus_tag="KOI47_RS36500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="FxLD family lanthipeptide"
                     /protein_id="WP_216207000.1"
                     /sec_met_domain="LD_lanti_pre (E-value: 4.5e-12, bitscore:
                     44.4, seeds: 21, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTVLTGEPGGVFDLDVRMETERILSEAVACQTEDGCGHTCQISA
                     CVSQL"
     gene            10001..12958
                     /locus_tag="KOI47_RS22690"
     CDS             10001..12958
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lanthipeptide_LanB_RRE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1155: Lantibiotic dehydratase domain protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF016615.5"
                     /locus_tag="KOI47_RS22690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="lantibiotic dehydratase"
                     /protein_id="WP_216207002.1"
                     /sec_met_domain="Lant_dehydr_N (E-value: 2.4e-174,
                     bitscore: 579.7, seeds: 73, tool: rule-based-clusters)"
                     /sec_met_domain="Lanthipeptide_LanB_RRE (E-value: 6.2e-12,
                     bitscore: 44.8, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Lant_dehydr_C (E-value: 5.7e-22, bitscore:
                     77.3, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPEVGYRHRGTGVLRASAQQVTPAWWPALSDARDCRAWLGEVWPT
                     VAVAVRHASPVLACGVEAILAGRPRSGRKVRRAALAVVRYVLRFQRSTPFGLFAGVAPL
                     TVSSTSSVRFGQQHRPVARPDHRWLHQVINRLKACSELLAQLDVVFHDAVERQGERLVL
                     AGPEVVSVRCTPAVRFVRRHAAGPVRVGVLAEALAAAFPGAGDAAVLVRSLLEHGFLVS
                     SLRAPSTVTDPLGFLTDSLQALDTEGTAVASLVNELGEIRRALDGHNQHPCEQARTELA
                     ARMQAIAGVPRGVLSVDLRLDGQVRLPERVVREMERAADVLARVAREHTGSRAWREYFT
                     AFCERFGTGTLVPLRLLVDPACGVGWPQGYPAGPAQGGRHVFSERDRLLLSWAAEATAG
                     GRREFELDAGAVDALAAVGGNPEVAPPHVDLGARIHAASTAALDRGEFRLTVAPGRAAG
                     TFSSRFTPLVPEAGLEAVFAGLPTITEGAVAAQVSCAPLYPGGENVARVPRCLPEIVSV
                     GEHEPAAIGVDDLAITATRHRLHLVSLSRRRVVEPLVLHALAPKQQPPLARLLGELPGA
                     LGTGWLGFDWGPVAGSLPFLPRLRHGRVILAPAQWRLTRHELPADTAGRDRALARWQAA
                     WGCPDRVQLRDFDQQLPLDLAVPAHREVLAHHLHGSEEAVLIESPEPGADGWLEGRPHL
                     VVLPLASRRRPEPAPRVESLPVLTHQHGHPPGSAHSGWLYAKLYLPAHRVDRLLVHQLP
                     DLLVELGERDWWFVRYPRTRDGDEPDHLRLRIRTTGDADKVLAALTTWADRLREDGLLS
                     RGALDTYYPETGRYRAIHDAERLFAADSRLVLACLTHRPGGVSPVAATGLSLFELAAAF
                     LGDRQHAADWLHHRAPRAVPGRAAVDQVIRLARGWPDTAEPAEVAAAHRDHGEAVRRYR
                     HALPADTDLDACLHALLHMHHNRALGVDPELEAVCLRLARQAATTWHTTHPGRSS"
     aSDomain        10451..10681
                     /aSDomain="Lanthipeptide_LanB_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing LanB protein in a class I
                     lanthipeptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_KOI47_RS22690_Lanthipeptide_LanB_RRE.
                     1"
                     /evalue="2.40E-14"
                     /identifier="RREFam001.1"
                     /label="KOI47_RS22690"
                     /locus_tag="KOI47_RS22690"
                     /protein_end="227"
                     /protein_start="150"
                     /score="44.8"
                     /tool="antismash"
                     /translation="HDAVERQGERLVLAGPEVVSVRCTPAVRFVRRHAAGPVRVGVLAE
                     ALAAAFPGAGDAAVLVRSLLEHGFLVSSLRAP"
     gene            12955..14058
                     /locus_tag="KOI47_RS22695"
     CDS             12955..14058
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1140: Lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF017000.5"
                     /locus_tag="KOI47_RS22695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="lanthionine synthetase C family protein"
                     /protein_id="WP_232376181.1"
                     /sec_met_domain="LANC_like (E-value: 1.7e-33, bitscore:
                     114.6, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAQSLADGPAGQALLALERDQDARDWLAAMVAEPVRAHPDEVSL
                     FEGAPAVAFTLAATRMADTQDVLDGHVRWITRARLKAAHHRLAAGALADTREFDLISGL
                     TGLGAYLLRRGGNHELLRDVLRYLVRLTHPHRGGLPGWWARSGPTGPGPGWHGGHGNPG
                     MAHGIAGPLALLALAMLRGIVVSGQAAAIDRVGTWLDRWRCGTPPRVWWPEAITRAEHD
                     RGEAFRPGPGRPSWCYGTPGITRALHLAGRALDDPARQHLAEEILALCVTDEAQLAQLA
                     DVSLCHGWAGLLHTAWRASHHSDRIATALPRLLHGLTDRLARRPPAGQGLLTGTAGALL
                     AQHAARTNTPPVTRWDACLLLNDEGTR"
     gene            14055..15299
                     /gene="fxlM"
                     /locus_tag="KOI47_RS22700"
     CDS             14055..15299
                     /GO_function="GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="fxlM"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PCMT"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:TIGR04364.1"
                     /locus_tag="KOI47_RS22700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="methyltransferase, FxLD system"
                     /protein_id="WP_216207005.1"
                     /sec_met_domain="PCMT (E-value: 2.1e-44, bitscore: 150.5,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNHATTSSPADLRETMITSVKQAGYAQRPEVERALRRVPRHEFVP
                     EADLDTAYDPWQAVITHRFTDGTALSCASAPSVVAMMLDQLAVEPGNAVLEIGAGTGYN
                     ASLLAELTNQDTHVVTIDLDGGVTTHATRNLAATGYHGVRVVTGDGALGVPEHGPYDRI
                     IATVSPWDIPTAWWQQLTPGARLVVPLRWRGQTRSVAFAHHNGRLVADSIELCGFVPLV
                     TDDDGELSAPITADGTIHLHWDRDQPVDPTVLHGVLDRPSNTAWSGVSIAGDEPHDGIW
                     LRLTVTDLRTCRLNAPADTPPEICAPISPLRAPALVDGTSLAYLTLRRHQGSGPSRWEL
                     GAIGHGPAATELATHLCDELRAWSIDRDRRKPNLTAYPADTPEHELTGTIIDKAHSKLV
                     LTYDTDEPHEHRYRA"
     gene            15317..15622
                     /locus_tag="KOI47_RS22705"
     CDS             15317..15622
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="KOI47_RS22705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_216207008.1"
                     /transl_table=11
                     /translation="MNESADHGITGSSIEIDNQCYARAVVLRGGLPALAIGYGGTDTVL
                     SAGPRLQDAAIAKEFAITLASAALAFAGGCTVRLTQRHNQHEPAQPRLNEHDSPDH"
     misc_feature    complement(15769..15784)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 17.13"
                     /tool="antismash"
     gene            15946..16566
                     /locus_tag="KOI47_RS22710"
     CDS             15946..16566
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF042914.1"
                     /locus_tag="KOI47_RS22710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SAV_915 family protein"
                     /protein_id="WP_216207009.1"
                     /transl_table=11
                     /translation="MDPDEVPRQAPDGLYLLTTPTGHGGVIELWTLRDGTSAVMGYSSI
                     GRLMVACGSGQPFRHMAADEVESTCESIGAKVVVVDTVPPGGRRYPEVDSRDQPDLPLL
                     DAEDPDQPVVYVPSRPYRAGQRDAVLELQPHEGRLTLLAYTSRELLEEGCGPYQAWVSI
                     PSHLLEEAAWRVGAEAVLFNPVLSEESRHAAPVLDWTRRDNNR"
     gene            16578..16919
                     /locus_tag="KOI47_RS22715"
     CDS             16578..16919
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="KOI47_RS22715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_216207012.1"
                     /transl_table=11
                     /translation="MGGNEGFSYSTAGLESVVSQLREGARHLDEANEAAVEMVDAGGSS
                     EIVGKALADLLMSSVNSAATMDNAAGKVDAAKGSYHDIENTNEGAMRKKQHDIMEDYPD
                     VHDMNVPLN"
     gene            16948..18174
                     /locus_tag="KOI47_RS22720"
     CDS             16948..18174
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="KOI47_RS22720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_216207015.1"
                     /transl_table=11
                     /translation="MGQALNTQVNGSSGTCVEAADWLAKLYSQAHQAAAAAAGARGTAE
                     ADWHGPAQEAFHEATTNVDTHTRAIADRAFECEWALRDFADSLDSINAKMDDALAKATA
                     AGLRAEGPFIIAPEAPAAPKLLPTGPCGTADATAIMQQNQEAIAAYNNGPLATYNAKAA
                     AYNECKAIVNQARNLEQTAHETLRAAMGKATETANDTVSSLFTWVSQTRSYVGGGENSR
                     RLAAAKAERLFAQSKFLNDFALGAVSDTNPAQQRILNRAAELANDGGKQQTRAQQFEKW
                     VKMIPKDVRDVVTRYPGQGAVERLSEHSNVKVPDFSSRMLRSVPYVGAGLTVVNESIGA
                     AKGEQSWGRAAADTAAAIGGGALGGALTGAVAGSAFGPFGTVVLGLAGGFGGAMFAQDI
                     VAGFAGDGK"
     gene            18187..18927
                     /locus_tag="KOI47_RS22725"
     CDS             18187..18927
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="KOI47_RS22725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_216207018.1"
                     /transl_table=11
                     /translation="MAGHHRRKTPQRTWHEFPQLPPRPNPDTGEPLPPHAPGYSGPDHP
                     GNNPRLAGPMFGPPEPPPGMGPCLAWHRDDITGNIRRYIVALAILALGSSVLSLLRGDT
                     FGDALTYWPVWIVIVVFAYLMSDPLTFKTMSAGADWLQWGTRKRWYHRTPRAGHVKFYD
                     LVSITASGSGITIYLRLEDTEGNVLYRMPHALQQNRHIWDLLYNGILHSVANGAEIDNL
                     AIKALRLDETQALQLRQQISTTDD"
     gene            complement(19091..23128)
                     /locus_tag="KOI47_RS22730"
     CDS             complement(19091..23128)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="KOI47_RS22730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_216207021.1"
                     /transl_table=11
                     /translation="MSTYGLHRYAASPEEPVPVDSDGFLKLDSKSGVVPVSLLPTLSRN
                     FALLAAGGAGKTTTTTALVAVEPDAEYVETPLETRDKLENLISGAAGTKKTLYFDALDE
                     AVASDQFILRWLARELGRPGAADGYWRLSCRAAAWDRVFATSLPDFKTWKLLPLDRVTA
                     AAVVGEAVGAADFDGAAFIEAAAAAGLGRLSGCLSQLIAVARFWHGRGVLPDTAVEAME
                     YEVAHLLQETNSQRLRDLPADRAMRIAMRLAAFETFSGTQAFAVSTSGAPSTLTVDQLP
                     SEPEPVETARAIDPADYRDVLDTALFDTGPAGAVVFRHQSYVEYSTAAYLVERKLQPGQ
                     VPALLGVHSNGLLPTSRLGVAAWLGALQPGLVESLVHANALMFASSGAATELPSDAIRA
                     AVVAALLDHAASGKIHTDWRVDPALLVHTSLEAELSQSLKALQRSQQLWWIARLAAAGQ
                     CTGLAAALVEAAVDTQWYPYARRATVIAVGELGDNDIITGLASILDQDEDPDHQVRAAV
                     IDVLYPKLMSTRTLLAALRPRSSYPVGYDYYYSRSLGELADRIPPTDLPLALDWLRQLD
                     DKSIARRYDRFVEGLLRQAWEHSDDTAVRQMLARMLVSASWRLQSREGRTTLPWIEREA
                     DRRHSLVLEMAAIQEDSWQAIILMGLLGSHDVEWLLDEVDTCPPSTAASLAECLARIQI
                     VDMTAALADRLLSLQPSHPAYDATHSLRGSVDMSSEIAQFQRKHAVAMQKAAEARTQAQ
                     EQAKLALNNALTHVDVDPGSWWQIPVLVQQARQGDAAPSGGHDLTAWPGWNELQPEDAA
                     KVVDTGIRYLEAHTPNPATWTPLISWTSDQVMPDWAGVYLLTTLVWHYPNKLSDVQLDV
                     WRRWISAIVAVPVFAGDDPDDLRGLLLDAIPTELRPVLADHAINHLEVLHAAGEHLSAY
                     GFYQHVVLEFADRMVAWLLDVSETSPTADELLSLVVRASATETALDLCHRLRNEPDSPL
                     AARAKELLPGLDPNSALDELTSADHTSAQVAAVVSRINSAGLDHDHVLSAARLLLDTFP
                     YHNDPPMRSGAVEPEDTARRLRSNLLQQLASAGRVDDLFTLLAHREDIEQQILGQYLAT
                     ARARQADLAVKAISPQTLLDLLRSADARLVRDDADLLTVILHQLDNLQHHLTHSTAFQE
                     IWGGNIPHSEDSITDWVKRRLKDRLSEGVVVDREVQAKRVKPKGVGTRIDGVATTFTET
                     KGTARVLFEAKLANNSEVLTAMRAQLIDRYLIPEGRRHGILLIYWIHPDRRPSGRGWPK
                     NLHPDKDALRATLKEQADAELKNGFHITPVILDITPPEGFAGKDNSKPKHDNTTDSSPE
                     GP"
     misc_feature    complement(19700..19702)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    23509..23520
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 19.28"
                     /tool="antismash"
ORIGIN
        1 ccaccagacg aacggcaggt cctcatgggc gcgtgcctca tgcgcggtca ggtccgggcc
       61 gccctgtggg acgctctcga acgggtcgtc gatcagcgag aacgcatgcc cgccctcgtt
      121 ctcgaagatg accgcatgga aggttccgcc gccggggtta cccgcgccga tcccgaccga
      181 caggcgagcg acgtgcgggt ctgccccagt ggtccaaccg aatgcgtacg aggccagctc
      241 accctgcggc ccgacaaact ccccgaacgc acgtcgatcc attcccgtaa cagccttcgt
      301 gggcacctcg accagcgcac cctccagcac ctgaacatcc acgcccgcac gatagccgat
      361 caagaaacca ctctctcagg tacacgccac ccctctgcca cttggctacc cggacacaca
      421 cagcggcacg agcggatggt tgacagatgt cgctgaccat cgtccccgat ggcagggata
      481 caccgaacat ctacaagttc gtcgcggtgg agttcaccgg cgtcccgcgg cagtcctcct
      541 ggtcgtcagt cgaggtcgtt gccgaccacc gcggaccact cctccgccgg tgcgggtcga
      601 tccttttcgt caagctgggt aggcatgacc tcgtcgagac ccgcgtgtgc tcctgcggct
      661 tcggaaccag ccatcacggt cgcctccgac agtcgcttgt tggcccgggt tccgctgccg
      721 aggtcggtca ccgtgacgtg cacggcccca ttcgcgtcga tgtcgacgag gacctcgatc
      781 tgcggtacgc cctggggcac cggaggcagg tcggtgagtt cgatgacgcc gaccttcttg
      841 ttgtcttcgg ccaggtcgtg gtcgccctgg aagacctgga cggccacggt ggtctggttg
      901 tcgtcggcgg tggtgaagat ctccgagcgc ttggtcggga gggtggtgtt gcgctcgatg
      961 agcctggtga acaccccgcc cttggtcgcg atgcccagcg acagcggggt cacgtcgagc
     1021 ggcaaaacgt ccttgacctc gcctttgagc acaccgcctt gcagcgcggc gccgaccgcg
     1081 accgccgtgt acgggtcaac ctcggccagt gggatcgggc tgtcgccgag ggacgtgagc
     1141 atccgcgaga tggccgggag tgccgcggag ccgcccacgg cggcgacgag gtccacctcg
     1201 tcagccgaga tgccgacgtc ccggaggacg tccatgacct tccgcctgca ccgttcgacg
     1261 agatccgtgg tccggcgctc gaacgcgatg cggtccaagg tgacgtctaa gtgcacgggt
     1321 agcccgtcag cctgggccag gtagggcagg tgcacgcgag cggtggtggc gtgcgagagc
     1381 tcgatcttgg ccttctctgc ctccttgcgc agtcgccacg ccgcagtgga gtccgaccgc
     1441 gggtcgacac cgctcgcctc gatcgcgagt tcgaccagcc agtcgagcag cctctggtcc
     1501 cagtccgacc cgccgaggcg ctcgtcgccg ctggtcgcgc ggatctcaac gaccccctcg
     1561 ccgagctcca cgactgagac gtccagtgtt ccgccaccga ggtcgaacac aaggatggtc
     1621 tgctccttgt cgccaagtgc ggaacccgcc gccaacgcag ccgccgcagg ctcgttgatc
     1681 atccgcacgg cgttgagacc ggcgaggcgc gcggcgcggc tcaaggcgtc ccgctcagcg
     1741 acgccgtagt gcgcggggat agtgatgacc gcatcgccca ccggctctcc gaggtacctt
     1801 tccgcatccc gcctgagctg gtcgaggatg aatgccgcca cgttctcggc actgtactcc
     1861 gcgtcggcga cgacaaagga ccggccagtc cccaacgccc gcttgacctc ggcgatcgtg
     1921 gtactcgggc gcaggtgcgc ctggtccttc gcgacggctc cgacatccac caccgatccc
     1981 tggatggtga cgacgctggg cgtgagctgc acgcccaggt ggttcgacac gaccacgggg
     2041 cggccgtcga ccaggacggc aaccaccgag ttcgtcgtgc caaagtcgat cccgacgctg
     2101 tgcgacgtgg gctcgaccgt ccgctcggcc gccagtccga ccgcgatcgg gacggcgctg
     2161 cccaccttct cccgccacac ggccagggcc cgctccgcca cagcctcgtc cgcgtcccgt
     2221 gtcagcggca ccagcgcctc tcgcgcagcg ttgccggtct ggacgtcgtc gaggagccgc
     2281 tcgagcccga gtgtggcccc gaagcgctcc cagggctctc cgttcaccac cgcgcgatgg
     2341 atcgcggcgg gtatcggtgg ctcagcctcg tggccctgat acagagcgcg gatgttgcgc
     2401 gcgaggtaga tggtcccgct gaggcggtcc atggacagct cgggcttctg attcgcgacc
     2461 tgttgcgcca cgcgcatgct gacgaagcgg tagaggtcct ccacgctgac ctgaccgtcg
     2521 gagtcctgat ccgccaggcc ggtgctcatc ccttcgatca ccgcggaggt gaagaccgag
     2581 ggctctcctg ccggcttgct cagcaccgtg gactcgtagg cgtactgcag ggccgagcat
     2641 gctgtgatga ccgctttacc gtggccctgg aaacgcttgc cgaccacagg ctcgtcctgc
     2701 gcgccccgtt gtcggaggcc acgcgtgtag ccgccactga agcagcagtc cagcagcagt
     2761 actgtcctgc gggcgcggga ctcatcgata cagtcgttga cgaactgggc ggagatacca
     2821 gtggccgcga ggtaggcgga ctcggtgtcc cgcgcgacga agtgcagctc acgagtagcg
     2881 gagacctgcc catggcagga catgtgcagc agaagcaggt cgtcctgctc cgcggtggca
     2941 aagaactcct cgatgtccct gcgcacggtc ctggcgtcct tgtcgggcac gacggtgaca
     3001 tcgaactcgc cgatcgcccg ggacccgagc acctcggcga gctgctgggc atcacctgcc
     3061 gcgcccggca gctcggtcca gcgcgggtcg tcgtacacct ggttcgctat gagcagcgcc
     3121 cgcttgcgca aatctgagct cccaaggtgt cagcgatcgc gaggaccgac tctccgtgtt
     3181 gttcgctacc gttatcccgc gcgatcaatc gcggcgcaag gacggcggcc gagcctcggg
     3241 cggccgacgc cacccgcgat tcgctccacg gatccacgtc gttctccgtc gttgcctcgg
     3301 cgacctcgcc ggtatcgttg accaagtgct cactatctcc cttgccgttg tcgatgacga
     3361 cccagagcgg gtcgacgacc tcactcgaca actcgcgcag gaactcaggg ccaccgaagc
     3421 cgaccgcgtc gaggtgatcc atgccccggt cccggagggc gccaggtcgt ctgcggggtg
     3481 gtcgtctcga tcgtcgtcgc tgtggcgacc tcgccggtgt tggtgtccct ggccggtgtc
     3541 ctgcgcgaat gggtcaatcg gcggaacaaa cgcagcatgg tgatccgcga cggcgaccgg
     3601 tcgatggagg taaccggcta cgacgctcag gatatcgccg ttttcctggg caagtgtcag
     3661 ccttcggggc aaccggagcg ggagcccggt gcacctgacg agcccgcctg acgccatccg
     3721 tggcgacctg gttacaagca gcgaaccgcc ccaccagtct gaacatgcgc tctcggcaga
     3781 agagtgcacg ctttgcggca tgacaggacg ttggaaaaga agcggaccgc ttcgccgcgg
     3841 cgctgtggcg ctcaagctgc gaggcgtcac gcgcgccagc tgatgtacgt caaaccgatg
     3901 aagctcggcg gcgggacgac tactctgacc gggtccgctg gctcagcgcc gctggcaggt
     3961 caaggccagg aaccgcggct actgccacgg aagcgggtac cgttgctcga tctcggctgg
     4021 cggcatcggc tccaacaggt cggtgaactg gaagccgctg tccaccgctg cgcggaggta
     4081 ggcgaactac tccgcgtcgg cgtatcccgg tggtaccgcc agaacagggg tgagcgaggt
     4141 gcgcccccgc ccgatgcaca tagctgggtg cagcccatgc catctcagcg atactcggcg
     4201 caccagagtg tcagcttcga cgccagtagt ttggtcgcca ccagtagagc gacgtgtgat
     4261 cggtcggcca aggtgcgctg ttgacaccct ggagctcgac gttgtcgacg gcgagatcga
     4321 tggggcgcca gccgtcgtcg accggctcgg atggggtggc tgtacgcacg agaccggtga
     4381 aacgaaactc catcgcaccg agttcggcgt aggcacgctg cgcatcaatc agtgcaggag
     4441 tattcgcacc gccgctccag tcaggccacc gcaactggac cgcatcgtcc tcccagaaac
     4501 acacttcgca gatctcgtgg gagcctggcg gctcagtgaa catcagatgc ccacagcacg
     4561 ggcacgggta ctccgcctcc acgatcgttc agtgtcagca cctgacagac aggagtcaac
     4621 tcgaatacca gactgtcctg aatggcatcc aagtctgcgc gatccatctg gtcgcgctga
     4681 atgtggcggt gtcagtatgc aaggttggag accgaagaca ccaacgacaa aatggaggag
     4741 acgttcttcg ccgactgtca gtgggaactt cgagcgggcg ccgttgcggg ccaggtccta
     4801 ccggatcgcc accaacgact gctcgacctg tttgcccagc ctgccgccgg tggcgaggtg
     4861 ctgcggctgc gcccaagcgc cgttctcacc ttcgtgaacg gccgcgttcg agatcgtcac
     4921 ccccgacagg cgccgctgaa agctgcgcga cggcgagccc ggaggaccac cgccaccagc
     4981 gcgtgacccc gtccacttat cggcaatagc atgccgtggg cccggtgcct cgcagcggtc
     5041 tgcgcgaaca tggcgcgcta ctggctgctg atgagttgtt cacgcaggat gtcgacgtgc
     5101 ccgcagtgct gggcgagttc gcgcagcacg tgcagataca cccaacgcag aggtagcggg
     5161 ccacggcggt tgccgtggac catgtcatct aaccccaggg acgaggtcgt gtgacgtgat
     5221 gccgcacgcg cgtcgcggtg tgcctgccgg gcagaggcga taatgtcgcc ctcatcgagg
     5281 atgaaggact cgtccggtgt cgcggggata tcgatctcgg cacgcgaccg gcaggtgagg
     5341 gcttcgtcga accagacctt ctcgatgaac gtcgcatgct tgactaggcc cagcagcgta
     5401 gtccgggacg gcaccaacga tcggcacacc tgctcctcgg tcagcctgtc caaaacacct
     5461 gccgagcgca ccccgatgct catcgaggaa cgcctcgaac tggacccgaa ccggctgatc
     5521 gatgacgtcc tcggcggaca ttgttgagag cgtggacatg tacaggacat cccagacgga
     5581 cgtccgcgaa caacacatat cggcacgggc gagtcctggg cgggcagaat cccagcatgg
     5641 acactgaacg tgagcacgac cgatggacgg cgaccgaacg tgagtgcggg tacatccgtg
     5701 cgcggttgcg gcttctcacc acggcgcaag gcggtcgcct cacctcgatc tgctcgggct
     5761 accgggcgca ctgggccttc ccgccagatg tcgatcagga acgccacgac gcgcctctga
     5821 ctctggagca agcgaggaca ctggcccctg gcgaggacgc gatggttcgc cttcacccgc
     5881 tcgtgcccga cctctggcca caagtcgcgg tgggcctgcg gctgtcgatg cttgagggag
     5941 cccgagtggt cgggctggcc gatgtcatgg agacagtctc tccggtccca tgaccgaaca
     6001 cgaccatcgg caggtgcgga tgttgctcgg ctgggctgtc tcgatcgcgg ttgtggagcg
     6061 tgcaccgcgt cgtgtttcac gtatccgggg tctctcccca gcgcggctgg ggagagggca
     6121 ctcggatgtc cacgttctcg atagggtcca cggccttgcc gagactcttg aggtggtcga
     6181 gaacgtccgc gaagctgccg atcaggatcg tcgtggcggg gcaccgggga cacggcttgt
     6241 cgcggcggca tcgagggtct ccgttgacca ggttgcgggc gtggttgtag gcactgatcg
     6301 ggtcgtcggc ccggatcagg tgccactcgc catgctggtg gtcggtgggt aggccggcgg
     6361 cgagtccggg ggctacgggg cgggtcgatg cggcaggcgt ggtggcggat gaggaagtcg
     6421 cggtcgaggg gatcgacttc gtcgtcctcg ggctggcggt cgaggtacca cgccaacgcg
     6481 tcggtgggtg gtcccggtcc ccacaacatg tcgatgggag actgcgtcgt ggtgtagaga
     6541 gcatcgaagc gccacaggtc gtccaggttc tgcgttgagg cgcgaaccag gatggtcatc
     6601 accggccctc ccagccggac atgagggagt tcggcggcag cacaggtttc cttgtcgccc
     6661 gccgagttcc aggacacggc gatcacagtg cgctggacag gtgccggatg aagccggcca
     6721 ccaggggtgg gtacatccca caggcagttg atgatctcgg ctacgtcgcg gatgctgcgg
     6781 gcggcctcga ccggggagct cagctggtag tgcgtgggat gggccgtcat gtcacgtaga
     6841 tgcttctgag tcgccgcgat ccgtcgcgcc cactgacccg gcagcagccc ttcctgctct
     6901 gcccagcgcc gcaagccgcc cagcatgccg ttaaaggatg ggatggtgct gccggatcgc
     6961 ggcaattcga ggatgcggtc cgcaggacga atattgtcga gttgatcctt gatgtcgtgg
     7021 aacgagccgc cggtcagaag cctggcggca ccggctcggt ccctgaccgg aatcccggtc
     7081 gcgtagtacg tcatgaaccg gtcccggaaa gccagctcca tgagcagccg ggcccggtcc
     7141 tcggcaaagg tgaacaggtc gtagctgagg gcaccataaa ttaacgctga tcggacctgg
     7201 tcgaaggcgt tgcgggtgtt ctccggtacc gcgtccgcca gaacgatcgc cgccatcagc
     7261 tcgtattgga aagccacggt gctctcggac gtcaagatgt gcgatccgcc cagcccccac
     7321 ggcgtgaagc cctgggtacg ccggtcgacg agccgcaact cctccagcgt gtgcggcagg
     7381 cagtctcgtc gctccgcatc cggcagtgtc tcgtcctcca cgacaggcct cctcctggac
     7441 atcagggccc gccgaccatg gcgagccgac caggatgtca caagcccggc tgccgccgca
     7501 tctgggtttg cccatcccga tccgcaccgc gcgctgcctc ggcgtagaag cttgtctcgg
     7561 ttgtcacggg ggcaacgcgg tcgcatttca cgaaatgaaa ccaggcacac cccggcacga
     7621 cggggtgtgc ggttcatcgt ccgatgagtg agtcgtgtat gtggtcgtcg agttcggtga
     7681 ggaagtgttc ggttcgccag gggcgcaggt gttgtcgggc tagccggatt cgctgtgccg
     7741 gtacgcgtcc gccggtggtg gcggtgatgt cgatggcctt gtgcaggagg tcggcgcagg
     7801 cggggtcgcc gagtcgcagt cgtgcgaggg cgaggtcggt gctgacgatg ccgcgttgaa
     7861 cggcgtcccg tgatgtcttc agggcgttga gtgagtgggc gaggctgtcg tgggcgcggt
     7921 tggcgtcgcc ggcgtggagt gcgcagagtc cgtcgaatcc gtggaggcgg tcggcgttga
     7981 acccgctgtg cgggtcgtcg gacgtgagtt gctcgacggt ccgccaggct cggtcgagtg
     8041 cggcgccggc ctcgcgggtc tggccggcgc gtgcgcagat ctcggcgtgc acggcgtgtg
     8101 cgcgggctcg aacggcgtag ctggatccct gatgggcgtc gatggtcgcg gcgtgggcga
     8161 tggtgcgggc tgtgtcgagg tcgttggtcg cgtgcagggt caccatcgtg tggctggtcc
     8221 gtaccgtcgc gcggtgattg cggtctttca gctgtccggc gacggcggtg gcgtcggtgt
     8281 agagcgcagt ggcgagttgg tcgtcgcggg tctcgaaggc cagccgtgcg gcaagggcgt
     8341 aggtgtgggt ggccagccgg gccagctcgt cgtgctgtcc ggggtggtcg cgctgcagga
     8401 gccggcggca ggactcgacg atcggcgcga gctggagctg gagccggacg aatggggtcg
     8461 atcccacctg cctggtgatc gccgtgacgg agcgctggag ctggccgagc aggtcgtggt
     8521 cgagcgggca ggagccgcgc tgaaccgccg tgatgccgaa gtgggtggct ggcgacagca
     8581 gcgtcgacga gtcgctgcgg gcgttctggg tgaccagatc aaggagcgct tggatgcggt
     8641 gcggtggcgt tccgaaaagg cggagcgcat ccagcagggt gccgagatcg gatccgggtc
     8701 ccagggccag gtcaccggag gggtgcgggc gtagaggtgg gcgagcagga cctggtagcg
     8761 atcgccgggg ctggttcgtt cggtgccgct ttcccatcgg gcgacggtgc gttggatgct
     8821 ggtgacctgg cggtgcgtca gcgaggtgac ggcaagctgg cgcgcggtgt cgcgcagtgc
     8881 tcgggccagg tcggcccagg accagccacg gccttcgcgc agctggcgca gcaggcgcgc
     8941 cccggtgtcc cgatcggtgc tcatggcatc cagtacacca tccccagcag atcagacggg
     9001 cacgaccagc cggggtttgt cctgctcggc ggcgtagttc acggtgtacc aggtgccgct
     9061 ggccggatcc gtgccgtgcg ggaaggcgat cacgaacctg ctgcggtcga ccatccatcg
     9121 gttgcgggcg tgataggccg aggcgccgag cgtgtcggcg tgcagttcga ccactccggt
     9181 gagccggccg gctcgctgcc atcggcgaat cacctcgccc gcggctgccg gctggtcggc
     9241 cacggtgcac ggcacgacaa cggtgaggtc ggcctgggtg tgactggcca gccagtccag
     9301 cgcggcggtg tcgatccccg cggctccgcc gaggtagaag gtggcgtccg ggtcggcgaa
     9361 cggccgcagg tagtcaccga acagtccggg taggtccgcc tcggtctggg gagggatcga
     9421 ccgtgcgccg gtgatcgtca cgtggcgggc caagctcgcg ctccctcccg gatgtcatcg
     9481 aatgtcatct acccacatcg tgcctggtca cgttctcatg aacgcaccgg ctgcggcgag
     9541 gctcgccccc cgacccgtcg cagccggttg cccacgccac ggggaccgtg aggaggagcc
     9601 tgctgaccac gaccacgtac ccgggtgcgg cggacgacct gctccacgtt tttggcacga
     9661 aagcgggtgg aatagcgcca ccaatgaatc aacagtgaaa atcaccccat taaatatgcg
     9721 cgcgaacggg aatggcgatt acgacaagag gagaagaggt gtcccgatga caacggtcct
     9781 caccggggaa ccaggcggcg ttttcgatct ggatgttcgg atggagacgg agcggatctt
     9841 gtccgaggcg gtggcgtgcc agaccgagga cgggtgtggg catacgtgcc agatttccgc
     9901 ctgtgtgtcg cagctgtgac tttctcgggg ttggggcctg gattcgttcc tggccccgcc
     9961 ccgggctcca cgtttgctga taggaacggg aggtgcgggg atgcccgagg tgggctaccg
    10021 gcatcgcggt acgggggtgc tgcgtgcgtc ggcgcagcag gtcacaccgg cgtggtggcc
    10081 ggccctgtcc gatgcgcggg attgccgcgc gtggctgggt gaggtgtggc cgacggtcgc
    10141 ggtggcggtg cggcatgcga gcccggtgct ggcctgcggg gtcgaggcga tcctggccgg
    10201 gcgtccgcgg tctgggcgga aggtgcgtcg cgcggccctg gccgtggtcc ggtacgtgtt
    10261 gcgtttccag cgttcgaccc cgttcggttt gttcgccgga gtcgccccgc tcacggtcag
    10321 cagcaccagc agtgtccggt tcggccagca gcatcggccg gtcgcgcggc cggatcaccg
    10381 gtggctgcac caggtgatca accggctgaa agcgtgctcg gagctgctgg cgcagctgga
    10441 tgtggtgttc cacgacgcgg ttgagcggca gggcgagcgg ctcgtgctgg cggggccgga
    10501 ggtggtgagt gtccgctgca ccccggcggt gcgattcgtg cgtcgccacg cggccggtcc
    10561 ggtccgcgtc ggcgtgttgg ccgaggcgct ggcggcggcg ttccccggtg ctggcgatgc
    10621 ggctgtgctg gtgcggtcgt tgctggagca cggtttcctg gtcagtagtc tgcgcgcgcc
    10681 gagtacggtc accgacccgc tgggcttcct taccgattcc ttgcaggcgc tcgacaccga
    10741 gggcaccgcg gtggcgtcgc tggtgaacga gctgggcgag atccgccgcg cactcgatgg
    10801 gcacaaccag cacccgtgcg agcaggcgcg gaccgagctg gccgcacgga tgcaggcgat
    10861 cgcgggcgtg ccgcgagggg tgttgtcagt ggacctgcgg ctggatggcc aggtgcgcct
    10921 gccagagcgg gtggtacggg agatggaacg ggccgccgac gtgctggccc gggtggcgcg
    10981 ggaacacact ggaagccggg cgtggcggga gtacttcacc gcgttctgcg aacggttcgg
    11041 caccggcacc ttggtcccgc tgcggctgct ggtggacccg gcctgcggcg tgggctggcc
    11101 gcagggctac cccgccgggc ccgcgcaggg cgggcggcat gtgttctccg agcgggaccg
    11161 cctgttgctg tcctgggccg ccgaggccac ggccgggggc cggcgcgaat tcgagctcga
    11221 cgccggggcg gttgatgcgc tggccgccgt gggcggcaac ccggaggtcg cgccgccgca
    11281 tgtcgacctg ggcgcgcgga ttcacgccgc cagcactgcc gcgctggatc ggggcgagtt
    11341 ccggctgacc gtggcaccgg gccgggccgc gggcactttc tcctcccggt tcaccccgct
    11401 ggttcccgaa gccgggctgg aggcggtgtt cgccgggctg cccaccatca ccgagggggc
    11461 ggttgcggcg caggtgtcct gcgcgcccct gtatcccggt ggggagaacg tcgcccgcgt
    11521 cccccgctgt ctgcccgaga tcgtctccgt cggcgaacac gagcccgccg cgatcggggt
    11581 ggacgacctg gcgatcaccg caacccgcca ccggctgcac ctggtcagcc tgtcgcgccg
    11641 ccgggtggtc gagccgctgg tgctgcacgc gctcgcgccg aagcagcagc cgccgctggc
    11701 gcgcctgctg ggcgagctgc ccggggcgct gggcacgggg tggctggggt tcgactgggg
    11761 tccggtggcc gggtcgttgc cgttcctgcc gcggctgcgc cacgggcggg tcatcctggc
    11821 tccggcgcag tggcgactca cccggcacga gctgcccgcc gacacggctg gtcgggaccg
    11881 ggcgctcgcc cggtggcagg cggcatgggg gtgtccggac cgggtgcagc tgcgggactt
    11941 cgatcagcag ttgccgctgg acctggccgt gcccgcgcac cgggaggtgc tcgcccacca
    12001 cctgcacgga tctgaggagg ccgtgctgat cgagtccccc gagcccggcg ccgacgggtg
    12061 gctggagggc cgtccgcatc tggtggtgct gcccctggcc tcccgccgca ggccggagcc
    12121 cgcgccacgg gtcgagtcgt tgcccgtgct gacccaccag cacggccacc cacccggctc
    12181 ggcccactcg gggtggctgt acgccaagct ctatctgccc gcgcaccgtg tggatcggct
    12241 gctggtgcac cagctgccgg acctgctggt cgagctgggt gagcgggact ggtggttcgt
    12301 gcgctatccc cgtacccgcg acggcgacga accggatcac ctgcggctgc gcatccgcac
    12361 caccggcgac gccgacaagg tgctcgccgc cctcaccacc tgggccgacc ggctccgcga
    12421 ggacgggctg ctgagccggg gggcgttgga cacctactac cccgagaccg gccgctaccg
    12481 cgccatccac gatgccgagc ggctgttcgc cgccgactcc cggctggtgc tcgcctgcct
    12541 cacccaccgc ccaggtgggg tgtccccggt cgcggccacc ggtctgtccc tgttcgagct
    12601 ggccgccgcg ttcctcggcg accggcagca cgccgccgac tggctacacc accgggcacc
    12661 ccgcgctgtg cccggccggg ccgcggtcga ccaggtcatc cggctcgccc gcggctggcc
    12721 ggacaccgcc gagccagccg aggtggcagc cgcacaccgg gatcacggcg aggcggtgcg
    12781 ccgctaccgg cacgccctgc ccgccgacac cgatctcgac gcctgtctcc atgcgctgct
    12841 gcacatgcac cacaaccgcg ccctcggcgt cgatccagaa ctcgaggcgg tgtgcctgcg
    12901 gctggcccgg caggccgcca ccacctggca caccacccac ccggggcggt cgtcgtgacc
    12961 gcacagtcgc tggccgacgg gcccgccggg caggcgctgc tggcgctgga acgcgaccag
    13021 gacgcccggg actggctggc cgcgatggtg gccgagcccg tgcgcgccca ccccgacgag
    13081 gtcagcctgt tcgagggagc ccccgcggtc gccttcaccc tcgccgccac ccgcatggcc
    13141 gacacccagg acgtgctgga cgggcacgtc cggtggatca cccgggcgcg gttgaaggcc
    13201 gcgcaccacc gcctcgccgc cggggcgcta gccgacacgc gcgagttcga cctcatctcc
    13261 ggcctcaccg ggctcggcgc ctacctcctg cgccgcggcg gaaaccacga gctgctgcgg
    13321 gacgtgctgc gctacctggt gcggctgacc cacccccacc gcggcggact gcccggctgg
    13381 tgggcacgca gcggccccac cggtcccggc cccgggtggc acggcgggca cggcaacccc
    13441 ggcatggcgc acggcatcgc cgggccactc gcgctgctgg cgctcgccat gctgcgcggg
    13501 atcgtcgtat ccgggcaggc cgccgccatc gaccgcgtcg gcacctggct ggaccgctgg
    13561 cgttgcggca ccccacccag ggtgtggtgg cccgaggcga tcacccgcgc cgagcacgac
    13621 cgcggcgagg ccttccgacc cggtccgggc cggccgagct ggtgctacgg cacccccggc
    13681 atcacccgcg ccctgcacct ggccggccgc gccctcgacg accccgcacg gcaacaccta
    13741 gctgaggaga tcctggcgct gtgcgtcacc gacgaagcac agctggccca gcttgcggac
    13801 gtgtcgctgt gccacgggtg ggccggcctg ctgcacactg cctggcgcgc cagccaccac
    13861 agcgaccgca tcgccaccgc tctgccccgt ctgctccacg gactcaccga ccgcctggcc
    13921 cgccggccac cggccgggca gggactgctc accggcaccg ccggggccct gctggcccag
    13981 cacgccgccc gcaccaacac gccaccggtc acccggtggg atgcctgcct gctgctcaac
    14041 gacgaaggga cacgatgaac cacgccacca ccagctcacc cgccgacctg cgcgagacca
    14101 tgatcaccag cgtcaagcag gccgggtacg cccagcgccc cgaggtcgaa cgggcactgc
    14161 gccgggtccc gcggcacgag ttcgtgcccg aggccgacct ggatacggcc tacgacccct
    14221 ggcaagccgt catcacccac cgcttcaccg acggcaccgc tctctcctgc gccagcgcgc
    14281 cctccgtggt cgccatgatg ctcgaccagc tcgccgtcga acccggcaac gccgtgctgg
    14341 agatcggggc cgggaccggc tacaacgcca gcctcctcgc cgaactcacc aaccaggaca
    14401 cccacgtggt caccatcgac ctcgacggcg gcgtcaccac ccacgccacc cgcaacctgg
    14461 ccgcgaccgg ctaccacggt gtccgcgtcg tcaccggcga cggcgcgctc ggcgtccccg
    14521 aacacggccc ctacgaccgg atcatcgcca ccgtctcccc ctgggacatc cctacagcct
    14581 ggtggcaaca actcaccccc ggcgcccgtc tcgtagtccc gctgcggtgg cgcgggcaaa
    14641 cccgcagcgt cgccttcgcc caccacaacg ggcggctggt ggccgactcc atcgaactgt
    14701 gcggcttcgt ccccctcgtc accgacgacg acggcgaact ctccgccccc atcaccgccg
    14761 atggcaccat tcacctgcac tgggaccgcg accaaccggt cgaccccacg gtcctgcacg
    14821 gagtcctcga ccggccgagc aacaccgcct ggtccggcgt cagcatcgcc ggagacgaac
    14881 cccacgacgg catctggcta cgcctcactg tcaccgacct ccgcacctgc cgactcaacg
    14941 cccccgccga taccccgccc gagatctgcg cccccatctc gccgttgcgc gcgcccgccc
    15001 tcgtcgacgg aacctccctg gcctacctca ccctccgccg acaccaaggc agcggaccca
    15061 gccgctggga actcggcgcc atcgggcacg gaccagccgc caccgaactg gccacccacc
    15121 tctgcgacga actccgcgcc tggtccatcg atcgagaccg gcgcaaaccc aacctgaccg
    15181 cctaccccgc cgacaccccc gagcatgagc tgaccggcac catcatcgac aaggcccaca
    15241 gcaagcttgt cctcacctac gacaccgacg aaccacacga gcaccggtac cgtgcctgat
    15301 acggaaacgg acgttgatga acgaaagcgc cgatcacggc ataaccggat cgtcaatcga
    15361 gatcgacaac cagtgctatg cacgtgccgt ggtccttcgt ggaggactgc cggcgttggc
    15421 tatcggctac ggcggcactg acacggtctt gtccgccggt ccacggttgc aggacgctgc
    15481 gatagcgaaa gaattcgcca tcactctcgc ctcggcagcg ttggcgttcg cgggcggctg
    15541 caccgtccgt ctgacacaga gacataatca gcacgagccc gcgcagccac gcctcaacga
    15601 acacgacagc ccggatcact gacatcgcct cgacgagtgt cgatccctga cggcggatca
    15661 tgtccgattc tccggcccga ggtagctgac gctcccgagc gagcaggaca cgatccatga
    15721 ttcttcagtc cctcgccgcg ttgttgatct tatacgcgcc cgctcgaatg tgaccccaat
    15781 caccagggcc ggttcttgcg caaccgtcct gtacgcacag accctcgcgc ttacactgag
    15841 cgttcagggg gaacggtcat gtagctgagt tcggcgatcg ggaggggacc gtaggtgtcg
    15901 gggggagccg aggagcaagg tcggcacgga cgacggccac gcacagtgga cccggacgag
    15961 gtaccgaggc aggcgccgga tggcctgtac ctgctcacca cgcctacggg acatggcgga
    16021 gtcatcgagt tgtggacgct ccgtgatgga acctctgccg tgatgggtta ctcctccatc
    16081 ggtcggctga tggtggcgtg cggtagcggg cagccgttcc ggcacatggc agccgatgag
    16141 gtcgaatcga cctgcgaatc gataggtgcc aaggtcgtcg ttgtcgatac ggtgcctccc
    16201 ggtggccggc ggtatcccga ggtcgattcc cgggaccaac ccgacttgcc tctcctcgac
    16261 gccgaggatc cggaccaacc ggtcgtctat gtgccctcac ggccttaccg tgcgggtcag
    16321 cgcgatgctg tgctggagct tcaaccgcat gagggtcggc tgacactgct cgcctacacc
    16381 tcacgcgaac tactggagga agggtgcggg ccgtatcagg cgtgggtgtc gattccttct
    16441 cacctgctcg aggaagccgc ctggcgggtc ggggctgagg cggtgctgtt caaccctgtc
    16501 ctgtcggagg agtccagaca cgccgcaccg gtgctggact ggacccgccg cgacaacaac
    16561 cgataggagc atcgcacatg ggtggtaacg agggattcag ctacagcacg gccggactgg
    16621 aaagcgtggt cagccagcta cgcgagggcg cccggcacct cgacgaagcc aatgaagccg
    16681 cggtggagat ggtcgacgcc ggtggttcct cggagatcgt ggggaaggcg ctcgccgact
    16741 tgctgatgtc gtcggtcaac tccgcggcga cgatggacaa cgccgcgggc aaggtcgatg
    16801 cggcgaaggg cagctaccac gacatcgaga acaccaacga aggcgcgatg cgcaagaagc
    16861 agcacgacat catggaggac tatcccgacg tgcacgacat gaatgttccg ctgaactgat
    16921 ccgggccacc agggaagggg gagcgacatg ggacaggcgc tgaacaccca ggtcaacggc
    16981 agttcaggaa cctgcgtcga ggccgcggac tggcttgcca agctctacag ccaagcgcac
    17041 caagccgcgg cagcggccgc cggggcgcgc ggcacggccg aggccgactg gcacggcccc
    17101 gcgcaggaag cgttccacga ggccaccacg aacgtggaca cgcacacgag agccatcgcg
    17161 gaccgtgctt tcgagtgcga atgggcgttg cgggacttcg ctgactcgct ggactccatc
    17221 aatgccaaga tggacgacgc gctggccaag gccaccgcgg ccggcctgcg ggccgaaggc
    17281 cccttcatca tcgcccccga ggctcccgcg gcacccaagc tccttcccac cggcccctgc
    17341 ggcaccgccg acgccacggc gatcatgcag cagaaccagg aagccatcgc cgcgtacaac
    17401 aacgggccgc tggccacgta caacgccaaa gccgccgcct acaacgagtg caaggcgatc
    17461 gtcaaccagg cacgcaacct ggaacagacc gcgcacgaga cactccgcgc ggcgatgggc
    17521 aaggcaaccg aaacggcgaa cgacacggtc tcctcgctgt tcacctgggt ctcccagaca
    17581 cgcagctacg tcggaggagg agaaaactcc cgccgtcttg ccgcagccaa ggccgagcgc
    17641 ctgttcgcac agtcaaagtt cttgaacgac ttcgcgctcg gcgcggtctc cgacaccaac
    17701 ccagctcagc aacgcatcct gaacagggcc gcggaactcg ccaacgacgg cggcaagcaa
    17761 cagacccgcg cgcaacagtt cgagaagtgg gtaaaaatga tcccgaaaga cgtccgggac
    17821 gttgtcacgc gctatccagg acaaggcgcg gtagagcgcc tgtccgagca ctcgaatgtg
    17881 aaggtccccg acttctcctc caggatgctg cggtcggtgc cctacgtcgg tgctggcctc
    17941 accgtggtca acgaatcaat cggcgcagcc aagggcgaac agtcgtgggg acgagccgcc
    18001 gccgacacag ccgcggccat cggcggcggc gccctcggcg gggcgctgac cggcgcggtc
    18061 gccggtagcg ccttcggacc cttcggcact gtcgtcctgg gcctggccgg agggttcggc
    18121 ggcgccatgt tcgcacagga catcgtcgcc ggcttcgcag gagacgggaa ataggcgaga
    18181 cacgacatgg caggccatca ccgccgcaag acaccgcaac gtacctggca cgaattcccc
    18241 cagctaccac cccggccaaa ccccgacacc ggcgaaccac tcccccctca tgcccccggc
    18301 tactcaggcc ccgaccaccc cggcaacaac ccccggctcg ccggtcccat gttcggcccg
    18361 cccgagccac caccagggat ggggccgtgc ctggcctggc accgcgacga catcaccggc
    18421 aacatccgac gctacatcgt cgccctggcc atcctcgccc tcggcagctc cgtgctgtca
    18481 ctcctgcgcg gcgacacctt cggcgacgcc ctgacctact ggccagtatg gatcgtcatc
    18541 gtcgtcttcg cctacctgat gtcggacccg ctgaccttca aaaccatgtc cgcaggcgcc
    18601 gactggctcc aatggggaac ccggaaacgc tggtaccacc ggacaccacg cgccggccac
    18661 gtcaaattct acgacctcgt ctccatcacc gcctcaggct ccggaatcac catctacctc
    18721 agactggaag acaccgaagg aaacgtgctg taccggatgc cgcacgcact ccaacaaaac
    18781 agacacatat gggacctgct atacaacggc atcctgcact ccgtcgccaa cggagccgaa
    18841 atcgacaacc tcgccatcaa agctctccga ctagacgaaa cccaggcact gcaactacgc
    18901 caacagatct caacaacaga cgactagccc ggatctttcg cgggggcggc cgggttgggg
    18961 tccgtaacag aaacggtgtt tccggctctg gttgtcagta gctctcagcg cccggccagg
    19021 gcgtgaggat gtctacgggt tgccgatgat gagcactcct cgtttcgttg gcccgagcgg
    19081 ttgtaggcag ctaggggccc tcagggctgg agtccgtagt gttgtcgtgc ttcggtttac
    19141 tgttatcctt gcccgcgaat ccctccggcg gggtgatgtc gaggatgact ggtgtaatgt
    19201 ggaagccgtt cttcaactct gcgtcggcct gctctttgag agtagctcgg agcgcgtcct
    19261 tgtccgggtg gagattcttg ggccagccac gtccgctagg gcgacggtcg gggtggatcc
    19321 agtagatgag caggatgccg tggcgtctgc cttccgggat gaggtaacgg tcgatcagtt
    19381 gtgcccgcat agctgtcagg acttctgagt tgttcgccag tttcgcctcg aacagcaccc
    19441 gggctgtgcc cttggtctcg gtgaacgttg tggcaacgcc gtcgatccga gttcctacac
    19501 ctttgggctt cacgcgtttg gcttggacct cccggtccac gacgacgccc tcagagaggc
    19561 ggtctttgag gcgccgcttc acccagtcgg tgatgctgtc ctccgaatgg gggatgttgc
    19621 cgccccagat ctcctggaac gcagtgctgt gggtgaggtg gtgctgcagg ttgtcgagtt
    19681 ggtgcagaat gactgtgagt aagtcagcgt catcgcggac cagtcgggcg tcggcggagc
    19741 gtagaaggtc cagcagggtc tgcgggctga tggccttgac ggcgaggtcg gcttggcgtg
    19801 cgcgggcggt ggccaggtat tgccccagga tttgctgttc tatgtcttca cggtgtgcca
    19861 gcagagtgaa caggtcatcc acccgaccag ccgaagccag ttgctgcaga agattcgagc
    19921 gtagtctgcg ggccgtgtcc tctggctcca cagcgccact tctcatcggc gggtcgttgt
    19981 ggtacgggaa cgtgtcaagc agaagccggg cggccgagag cacgtggtcg tggtcgagcc
    20041 cagcggagtt gatcctgctg acgactgccg cgacctgtgc ggatgtgtga tccgcgcttg
    20101 tgagttcgtc gagggcggag ttcggatcca gtcctgggag cagttccttc gcgcgagcgg
    20161 ccagtggaga gtctggctcg ttgcgcagtc ggtggcacag gtcgagagcg gtctcggtcg
    20221 cacttgctcg gacgactagg gacaggagtt cgtccgcagt cgggctggtc tcggacacgt
    20281 cgagcagcca ggcgaccatc cggtcagcga actccagcac cacgtgctgg tagaacccgt
    20341 acgcggacag gtgttctcct gcggcgtgca gcacctcaag gtggtttatc gcgtggtccg
    20401 ccagcaccgg ccgcagctcg gtcgggatgg cgtcaagcag gagcccgcgc aggtcgtcag
    20461 gatcgtcgcc tgcgaagacg ggcacggcaa cgatggcgct tatccagcgg cgccagacat
    20521 ccagctgaac atcggagagc ttgtttgggt agtgccagac aagcgtggtg agtagataca
    20581 cgccggccca gtccggcatg acctgatcgc tggtccacga gatcagaggc gtccacgtgg
    20641 ctgggttcgg cgtgtgcgct tcgaggtagc ggataccggt atcgactact tttgcggcgt
    20701 cctcgggctg tagctcgttc caacccggcc atgcggtcag gtcgtgcccc cctgacggtg
    20761 cggcgtcgcc ttgtctggct tgctggacga gtacgggtat ctgccaccag gagccgggat
    20821 ccacgtcgac gtgcgtcagg gcgttgttga gggcaagctt cgcctgctcc tgggcctggg
    20881 ttcgcgcctc agcggccttc tgcatagcga cagcgtgctt acgttggaac tgggcgattt
    20941 cgctcgacat gtccacgctg ccgcgcaaag agtgggtggc gtcgtaggca gggtggctag
    21001 gctggaggct caacaaacga tcagcgagcg ccgcggtcat gtcaacgatc tggatgcgtg
    21061 ccaggcattc ggctagtgac gcggcagtag acggcgggca ggtatcgacc tcgtcgagga
    21121 gccattccac gtcgtgcgac cccaacaagc ccatcagaat gatcgcctgc cagctgtcct
    21181 cctggatggc cgccatctcc aggacgaggc tgtgccgacg atccgcttct ctttcgatcc
    21241 acggcaaggt ggtgcgtcct tcccgggact ggaggcgcca gcttgcggag acaagcatcc
    21301 gcgcgagcat ttgtcggaca gcggtgtcgt cgctgtgctc ccacgcttgc cgcagcagtc
    21361 cttcgacaaa ccgatcgtag cggcgggcaa tcgacttgtc gtcgagttgc ctcaaccagt
    21421 cgagtgcgag gggaaggtcg gtcgggggaa tgcgatcagc aagctcgccg agcgaacggc
    21481 tgtagtaata gtcgtagccc acgggatagg aggatcgtgg tcggagggcc gccagcaatg
    21541 tccgcgtgga catgagcttc gggtacagga cgtcgatgac ggccgctcgc acttgatggt
    21601 cagggtcctc gtcctggtcc aggatgctcg caagtccggt gatgatgtcg ttgtcgccca
    21661 gctcgccgac agcgatcaca gtcgcacgac gtgcgtaggg gtaccactgc gtgtcgaccg
    21721 cagcctccac caacgccgcg gcaagcccgg tgcactggcc agcggcggct aggcgggcga
    21781 tccaccagag ctgttgagac cgctgcaaag ctttcaagct ctggctcagc tctgcctcaa
    21841 gggaggtgtg gacgagcagt gcgggatcga ccctccagtc cgtgtggatc tttccgctgg
    21901 ccgcgtggtc aagcagggcg gcgaccacag ccgcacgtat cgcatccgag ggcagttccg
    21961 tcgccgcacc ggacgatgcg aacatcagag cgttggcgtg gaccaggctc tcgaccaacc
    22021 cgggttgaag cgctccgagc caggcggcca ctccaagccg actagtgggg agcagtccgt
    22081 tggagtgcac gcccagcagg gcgggaacct ggccaggttg cagcttccgc tcgaccaggt
    22141 atgcggcggt cgagtattcg acgtagctct ggtgtcggaa cacgactgcg cctgccggac
    22201 cagtgtcgaa cagcgcagta tcgagtacat cgcggtagtc ggcgggatcg atcgctctgg
    22261 ccgtttcaac gggctcaggt tcggacggca actgatcgac ggtcagcgtg ctgggagcgc
    22321 ctgaggttga gactgcgaat gcctgggtac cgctgaacgt ctcgaacgcc gccagccgca
    22381 tggcgatgcg catcgcccgg tcagcaggaa gatcgcgtag acgctgggag ttggtctcct
    22441 gaagcaggtg cgcgacctcg tactccatgg cctcgaccgc ggtgtcgggc aggaccccgc
    22501 ggccatgcca gaaccgtgcc accgcgatca actggctcag gcagcccgac agcctgccca
    22561 accccgccgc tgccgcagcc tcgatgaacg cggccccgtc gaagtcagca gcacccacag
    22621 cttccccgac taccgccgca gccgtgaccc ggtccagggg aagcagcttc cacgtcttga
    22681 agtccggcaa ggacgtggcg aagacccggt cccacgccgc tgcccggcaa gatagacgcc
    22741 agtacccatc ggcagcccca ggccgaccta gttcacgggc caaccagcgc aggatgaact
    22801 gatcgctggc aacggcctca tccaaggcgt cgaagtacaa agtcttcttc gtgcccgcgg
    22861 cccctgaaat caggttctca agcttgtcac gcgtctcaag cggagtctcg acgtactcgg
    22921 catccggctc gaccgcgacg agggcggtcg tcgtcgtggt cttgcccgcc ccacctgctg
    22981 ccaaaagggc aaagttgcgg gagagcgtcg gcaggagcga gaccggcacc acaccgctct
    23041 tgctatcaag cttcaagaag ccatcactgt cgacggggac gggctcctca ggagacgcgg
    23101 catagcggtg aaggccgtac gttgacacct caccacctca ccacaccgat gttgccttgc
    23161 gaacaccgcc acgccgacgg ctgccattcg tgtcgccatc gttggcagac acgtccggac
    23221 gtcaacctcc accgtgccga cacaccgtct gccgccaact cgggttgagc tggtggtccc
    23281 gtcgattcgg ctctgaccat cgccacgagc aacagagcgc gtgcggctcc gatacggagc
    23341 actgggagga ccgggcgacg gactcagtct cggccgccag cacctcgcgg gctcgaatca
    23401 cctcataggt ggggctgaca cgtgggaccc tgacgtcatg ctccaggtca tcacggggat
    23461 gtacttccag gatgtacggc tcaacgagac cgaacatcgc cggaccctgt atacgaacgc
    23521 gtccttctga ggcgtgacca tgtcgacata cctatcggtc atttgacgcc ggcaacagag
    23581 tggtccaccg tcaacacgat tctcgcgtac ttcaccgaac gtcttgaagc ggtcctacct
    23641 gacggcagcg acgacttcat gatctcaacc ggcggtgatg ctatcgcaga cgatctcgcc
    23701 gtcgtgcttt cgtttgcgct cggtgctacg ttcactccga accgagagaa ggccgaccga
    23761 ctgatccgtg caccgtcggg gtcactccac agtccagccc cagccgacat tcttccgcgc
    23821 accttcaccc cgcaggtcgt actcaacgat ggtgatcttg atgatctgcg cgcatttatg
    23881 atcgagttgc tggcacttaa ccgaggcgtc ttcgaacgga cgatgagggc gatgcggcgc
    23941 atcgttacgg cgagcgagcg cgtcgccgag gatccgacgc tttcctacac tgactacgtc
    24001 gccgcccttg agtcactctc gacggacgtc aaggtgcccg ctccgacttg gaaccgtc
//
