LOCUS       NZ_CP076538            22350 bp    DNA     circular CON 16-DEC-2024
DEFINITION  Amycolatopsis aidingensis strain YIM 96748 chromosome, complete
            genome.
ACCESSION   NZ_CP076538
VERSION     NZ_CP076538.1
KEYWORDS    RefSeq.
SOURCE      Amycolatopsis aidingensis
  ORGANISM  Amycolatopsis aidingensis
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Pseudonocardiales; Pseudonocardiaceae; Amycolatopsis.
REFERENCE   1  (bases 1 to 7657695)
  AUTHORS   Li,R.
  TITLE     YIM 96748 draft genome
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 7657695)
  AUTHORS   Li,R.
  TITLE     Direct Submission
  JOURNAL   Submitted (08-JUN-2021) Yunnan University, Yunnan Institute of
            Microbiology, 121 Street, Yunnan 650000, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdevono v. 2.04
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 57.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_018885265.1-RS_2024_12_16
            Annotation Date                   :: 12/16/2024 14:59:15
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,118
            CDSs (total)                      :: 7,060
            Genes (coding)                    :: 6,941
            CDSs (with protein)               :: 6,941
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 44 of 119
            Pseudo Genes (incomplete)         :: 87 of 119
            Pseudo Genes (internal stop)      :: 2 of 119
            Pseudo Genes (multiple problems)  :: 13 of 119
            CRISPR Arrays                     :: 4
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 14:56:56
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 3874413
            Orig. end                         :: 3896763
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP076538.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22350
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="20"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..22350
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22350
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:12350](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12350)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    complement(691..711)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 19.9"
                     /tool="antismash"
     gene            760..1362
                     /locus_tag="KOI47_RS36290"
     CDS             760..1362
                     /GO_function="GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013646.5"
                     /locus_tag="KOI47_RS36290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_216217764.1"
                     /transl_table=11
                     /translation="MQKTVTIVGAGLGGLTLARVLQAHGVAATIYEGEASATARAQGGL
                     LDIHEETGQVALRAAGLYDEFRALVRPGEDAKRVVDRHGTILLDRPTDPRSARPEVDRG
                     ELRRLLIDSLAPGPSGGATSSPRSGTTRRAASTSPSRRVPPSAPTSSSARTAPGRRSGR
                     CSPRPSRATAVPASSGSPSPRAAGTTARAWPRSAAAH"
     gene            1335..1994
                     /locus_tag="KOI47_RS36450"
     CDS             1335..1994
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1087: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: protein motif:HMM:NF013646.5"
                     /locus_tag="KOI47_RS36450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="WP_408629830.1"
                     /transl_table=11
                     /translation="MATIGSGTLMAVAPGQGIIVHRDADGGVRGYVALNKPDEWMRSID
                     FGDPTAGLHRLAHEFDGWSPLLTALVTGSDVEPWLRPIHALPVGLSWNRVPGVTLVGDA
                     AHLMSPFAGEGANLAMYDGADLARELAGHPDVETALAAYEKRLFPRSREVAAHSAHNLE
                     TFFGQEAPHSVVTLCGGSAQAVKSAVRQPWSSGGASGRSRSTATSDSSSCRSPHRR"
     gene            complement(<2018..2134)
                     /locus_tag="KOI47_RS36455"
                     /pseudo=""
     CDS             complement(<2018..2134)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012655.5"
                     /locus_tag="KOI47_RS36455"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="TetR family transcriptional regulator"
                     /pseudo=""
                     /transl_table=11
                     /translation="MVRPGGRSARVQESVHEAVRALIAESGREALTVPLVAAR"
     gene            complement(2205..3596)
                     /locus_tag="KOI47_RS17725"
     CDS             complement(2205..3596)
                     /GO_function="GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1105: amidase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020494783.1"
                     /locus_tag="KOI47_RS17725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="amidase"
                     /protein_id="WP_216204553.1"
                     /transl_table=11
                     /translation="MQLPDLTLAEASDAIRERRVSPVELVDSILDHIDQVEPRLQAYVA
                     VQADQARSAARDAEREIVAGRIRGALHGVPMGLKDLIDVAGTATTASSRVRAEHRADSD
                     STVFARLRTAGAILLGKTHTHEFAYGLTTPQTHNAWDQTRVAGGSSGGSAIAVAARIAT
                     FALGTDTGGSIRVPASLNGVVGLKPTYGLVSRHGVTSLSWSLDHVGQITRTVEDASLVL
                     SVLAGHDPRDPASLPCTDGDYRPGPVADLTGLRVGVPRNYYFDHVDPHVDAVVRTAIDR
                     LADLGAHLVEVEIPMTRYIQATQWGLMVPEATAYHERSLRAVPDLYAADVRALLEAGEL
                     ITAGDYLRAQRARTLMRQAWARLLDEVDVIAAPTVPMTAVPANLETITWSDGTVESVSD
                     AYVRLCAPANLTGIPSLSLPVGHDPAGMPIGMQLLGRPRSEAVLLRVGHAHAQTQPARP
                     LAPMA"
     gene            complement(3583..3807)
                     /locus_tag="KOI47_RS17730"
     CDS             complement(3583..3807)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010695949.1"
                     /locus_tag="KOI47_RS17730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_216204555.1"
                     /transl_table=11
                     /translation="MSAVELTPSEAARLAARAGLPLNDVRHTGVAVTANHIHSVVSILR
                     ELDFGDTPPASAYRAEEENTRKVTADAAA"
     misc_feature    complement(3863..3879)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 16.81"
                     /tool="antismash"
     misc_feature    complement(3876..3891)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 17.51"
                     /tool="antismash"
     gene            3905..4828
                     /locus_tag="KOI47_RS17735"
     CDS             3905..4828
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010695947.1"
                     /locus_tag="KOI47_RS17735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="WP_216204557.1"
                     /transl_table=11
                     /translation="MSKPSPNTAAGVPSATPPCWTVGDVTVHRIDEVLLPPATGPWLLP
                     GATTDLVGREEWLRPDFADSDGILQLHSHSFAFEKDGMRVLVDTAIGNGKTRANPAWHK
                     LSTGYLDNLRAAGFSPDSIDLVLLTHLHTDHVGWNTHEVDGTWVPTFGNARYVTSRTER
                     DFWAGYDMDEPRRHMFEDSVVPVEEAALLDLVDVPADGVEIASGLRLLPTPGHTPGHLA
                     IQLTSQGKTALITGDCIHHPVQFAHPAIGSCVDIHPEHSEATRRRMLAALADTDALVLG
                     THFPPPTAGRVVSHGNSYRMTSVPAA"
     misc_feature    4895..4909
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.91"
                     /tool="antismash"
     misc_feature    5342..5355
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.47"
                     /tool="antismash"
     gene            5694..>6035
                     /locus_tag="KOI47_RS36460"
                     /pseudo=""
     CDS             5694..>6035
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012464.5"
                     /locus_tag="KOI47_RS36460"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MTNTGSTFRRRPGILGRLGGRRRVGGLGRGGRAEERPAPDPPARR
                     GRPPRPGDRFTVAEQYRLCRDVADILAVREWCRAHSMKLRVLSGIVNLAAPDATTTMLV
                     NVLVSVGQFQ"
     gene            complement(6107..7447)
                     /locus_tag="KOI47_RS17745"
     CDS             complement(6107..7447)
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012296.5"
                     /locus_tag="KOI47_RS17745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="cytochrome P450"
                     /protein_id="WP_216204561.1"
                     /sec_met_domain="p450 (E-value: 1.4e-80, bitscore: 270.0,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAVPALATGGLPLVGHLLPLRRERRLAFLDSLRRHGSVVRIKLGP
                     RTIYLVTEAEMAREVLVVQAGSFDKGEGGAQLRVLVGNGVLTSERETHRRQRRLLQPHF
                     HRNRMAGYAEAMRQEIEQLSTTWRDGQRLDVRTEMHGLLLGITIRALLPSSIGTLHGDF
                     RRDFPLALREVQRRMFNPVRALTSRLPTPRNQRHARLLAGLHQAAAHAIATHHKAEAKD
                     TDLLTTLTGARDPDTGEPLSDTEIRDQVMTMLATGGETSTSALSWAFHELGRHPDLEER
                     LHTEVDQVLGGRAARYEDLPRLELTGRIISEVLRCYPPAWMISRRALADVDLGGYHVPA
                     GSPVLVIPYIVHRDPAVFPDPHRFDPDRWLPDRPTRIPHDAVIPFGAGVRKCIADHFAV
                     IETTLTLATLAGRWRLRPLPDHPVRPVTATTLVPEGLVMRAERRGGW"
     gene            complement(7556..9751)
                     /gene="helR"
                     /locus_tag="KOI47_RS17750"
     CDS             complement(7556..9751)
                     /codon_start=1
                     /gene="helR"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019814344.1"
                     /locus_tag="KOI47_RS17750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="RNA polymerase recycling motor ATPase HelR"
                     /protein_id="WP_216204566.1"
                     /transl_table=11
                     /translation="MSAQGYEEELRSERSHVAGLYARLDAERTRVRGAYEAALRGNGET
                     PMERDVEVRALSSEAKRLDVADAGLCFGRLDTESGGQLYIGRIGLFDEENAYDPVLLDW
                     RAPAARAFYVATGANPENMRRRRQFHTRGRQVLDFTDEVFGRPGEDERGDTALLAAVNA
                     PRGAGMRDIVATIQAEQDEIIRLDHPGVLVIEGGPGTGKTVVALHRVAYLLYTQRERME
                     RHGVLVVGPNPAFLDHIGRVLPSLGESDVVFMTPGDLLPGMRVTAEDTPEAARLKGSLR
                     ILDVLAAAVADRQRLPEQPVPITLGDVTVRIDAETAEWAIEEARASGRPHNEARAVFTE
                     IVTYVLTERAIARIGRGWLTREDRKAWEELRTDLLKQLAEDERFTAAVDELWPVLTPET
                     LLAELYSSPERLRAAGADQALWRAQGDAWTVPDVPLLDELVDLLGRDKAVDKAAERVAE
                     RQRRAEAEYAADVMDAMKLDREEMDEDVMLAAENLLYAEDLADRFVERDTRDLAERAAA
                     DRDWTYRHIVVDEAQELSEMDWRVLMRRCPGRSFTVVGDLAQRRSAAGATSWDAMLEPY
                     VPGRWVYRSLSVNYRTPAEIMAVAAALLAEFAPGLQPPESVRSCGVEPWSRRVTEEELR
                     PAIEEFVQEEAGREGTSVVIGPPGVPGAVRPAETKGLEFDAVLVVEPMRILADGPRGAA
                     ELYVALTRATQRLGVLHQGRLPRALAGLGAPAGARPA"
     misc_feature    9776..9785
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 14.45"
                     /tool="antismash"
     gene            complement(10001..11122)
                     /locus_tag="KOI47_RS17755"
     CDS             complement(10001..11122)
                     /GO_function="GO:0010333 - terpene synthase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0046246 - terpene biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF040195.4"
                     /locus_tag="KOI47_RS17755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="terpene synthase family protein"
                     /protein_id="WP_216204570.1"
                     /sec_met_domain="T1TS (E-value: 8.8e-63, bitscore: 211.8,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTDPCGKITAHSSKENDMPVVDLPVFDIPFPARSSPEVARARTA
                     NVARMKSHGMLGTPEAEHWYLSWDLGQGAGYAYPMAVGEDLDLAVDQFAFFFVFDDQFD
                     GPLGRDPARVATFVDDLIAVLYRPAGRPSPRGSSPLVTFFADMWERSQQGMPAAWITRA
                     AHNFEYYLAAHAAEAMDRVNAHVPSWEHFLHVRRGAGATRLMVDYGERFGHFTVPLALF
                     HTPQYRMMRQVGIDVPLLCNDVHSVYKEAPRGDVDNAVLVVEREHGCTRDEALRAVRDM
                     VIHDHIPRFQRLEQELPRICATLRLDDEQCTAVDKSVAAIKMWIAGYHQWEIETDRYTP
                     EGTIPADRPNYVEDLVITGNGSHRPESRQRHPQ"
     gene            complement(11119..11298)
                     /locus_tag="KOI47_RS17760"
     CDS             complement(11119..11298)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF014456.5"
                     /locus_tag="KOI47_RS17760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_216204572.1"
                     /transl_table=11
                     /translation="MDKRVLLAAPRGYCAGVERAVAIVGRALELHGAPVYVRHQIVHNT
                     HTTTNLNTGNRGLP"
     gene            complement(11313..12350)
                     /locus_tag="KOI47_RS17765"
     CDS             complement(11313..12350)
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004561481.1"
                     /locus_tag="KOI47_RS17765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_216204575.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 2.4e-59, bitscore:
                     199.5, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MASPSLTDTTAAPAVLQQARSLTVPALRQAIATLHPRLAQVAGYH
                     CGLTDQHGRPAPARVGKMLRPALVFLSARSTGVPAERLASEGVVAGAVAVQLVHEFSLL
                     HDDIMDRDRTRRGRPTAWAVHGVDTALLAGDALLALAVSTLAEHPQAEAVLAEAVVGLC
                     AGQADDLAFETRTTVTVADWERMAIGKTGGLICAACQLGALLTEADSRAIAVLGTAGTQ
                     LGLAFQAMDDWLGIWGDPKVTGKPAGADVAARKRSLPIVVTLTDADPAAQRLAAILATD
                     GELTTDDLAAATTALERTNAGQTTSRHARQHTDRARDAIAALTIPSDVRREWDHLISFL
                     ITRAT"
     gene            complement(12465..13568)
                     /gene="ispG"
                     /gene_synonym="gcpE"
                     /locus_tag="KOI47_RS17770"
     CDS             complement(12465..13568)
                     /EC_number="1.17.7.1"
                     /GO_function="GO:0046429 - 4-hydroxy-3-methylbut-2-en-1-yl
                     diphosphate synthase activity (ferredoxin) [Evidence IEA]"
                     /GO_process="GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /gene="ispG"
                     /gene_synonym="gcpE"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013676768.1"
                     /locus_tag="KOI47_RS17770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="flavodoxin-dependent
                     (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase"
                     /protein_id="WP_216204579.1"
                     /transl_table=11
                     /translation="MVPVTGLPLPAVRRVCRQVGVGTVLVGGGAPVSVQSMTTTLTADV
                     DATLQQIAELTAAGCDIVRVAVPSQDDADALPAIASKSTIPVVADIHFQPRYVFAAIKA
                     GCAGVRVNPGNIKRFDDRVGEIAHAARDAGVPIRIGVNAGSLDPKILDKHGGRAGAEAL
                     VESALWETSLFADHGFHDLKISVKHHDPVVMIDAYRQLAQQCDYPLHLGVTEAGPPPQG
                     VIKTATAFGALLSEGIGDTIRVSLTADPIEEVRAGEAILQALGLRPRTLDIVSCPSCGR
                     AQVDVYKMTAEVQAALDGLEVPIRVAVMGCVVNGPGEARDADLGVASGNGKGQIFVRGQ
                     VVDTVPEHEIPETLIAHAVRLAESDHR"
     misc_feature    13607..13620
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: medium, score: 20.8"
                     /tool="antismash"
     misc_feature    13900..13912
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 22.29"
                     /tool="antismash"
     gene            13937..15124
                     /locus_tag="KOI47_RS17775"
     CDS             13937..15124
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1077: phage integrase
                     family protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009078517.1"
                     /locus_tag="KOI47_RS17775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="WP_216204583.1"
                     /transl_table=11
                     /translation="MTLAVAAQGDGADKTGQERFAEFLRIYTSLNTRLAYATDLGIPLD
                     WVPGYTPPDPARRRGRSRRAAPTGLEWLPWCLRNGFGSFAEVRVEHVERWLDELAHAGY
                     SDATRGRMLSAVSAFYRKYLLREGLAEQNPAALVDRKTQHLNRSGGTPSVTARWSFEAC
                     RALLLAAYLLADRRRDGRRDRAMVEVLIGTGVRAEELVGTNLTDYRRPTGGDIGILRIH
                     GKGAKDREVALAPPVADAVDTYLAERRPPAAPAVRGQVGPTPAEPLFITSTGRRVHVSH
                     VQALLRRLCATFAPAPDAPPPRARWLRDLLGTEQAALIASHLGPLRDTIHPHSARHSYA
                     THAVERGVPPRQVQQDLGHSALSTTEGYLHDEDNIRNSGAHELAPALHRGWLAAP"
     misc_feature    complement(15238..15258)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 21.86"
                     /tool="antismash"
     gene            15243..15851
                     /locus_tag="KOI47_RS17780"
     CDS             15243..15851
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017988105.1"
                     /locus_tag="KOI47_RS17780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="dihydrofolate reductase family protein"
                     /protein_id="WP_216217366.1"
                     /transl_table=11
                     /translation="MKLTIMTQVTVDGVMQGNGATSDDRRNGFERGGWARGKGDDETRT
                     FITQTYQRAAAFLFGRRTYELFAGSWGSIDQMRAHPIGAALNETPKYLASTTLTAPRWE
                     DTTVLRGDLAAAIGELKAKPGGELQVHGSGVLTRWLLENGLVDEMTLLVIPVILGQGAR
                     LFPEAGPDLALDLVESRVDSKGVMIQVYRPDGRPQYATA"
     misc_feature    complement(15244..15258)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.8"
                     /tool="antismash"
     misc_feature    complement(15889..15903)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.23"
                     /tool="antismash"
     gene            15905..16228
                     /locus_tag="KOI47_RS17785"
     CDS             15905..16228
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020640379.1"
                     /locus_tag="KOI47_RS17785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="YciI family protein"
                     /protein_id="WP_216204586.1"
                     /transl_table=11
                     /translation="MQYLVSVIDDKSNPGSTDRRPAISAFNERLIAEGYWVFAGGLADT
                     DTATVIDNRGEQAVFSDGPFVESKEYLAGIWVWEAPDLDVALKLAAEASKVCDRKVEVR
                     PFR"
     gene            16225..17469
                     /locus_tag="KOI47_RS17790"
     CDS             16225..17469
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020640378.1"
                     /locus_tag="KOI47_RS17790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="RNA polymerase sigma factor"
                     /protein_id="WP_216204589.1"
                     /transl_table=11
                     /translation="MSDVEEAITRAHRAEWARVVAALTRRFGDLDTAEEAAAEAFATAV
                     ERWPADGVPPNPGAWLTTTANHKAIDRIRRENKRDDKHKEAQMVYDDSREPLGAIDGAI
                     EDERLRLIFTCCHPALAMQTRVALTLRMVGGLTVPEIARAFLVAETAMGQRITRAKAKI
                     KAARIPYRVPSAEDLPARVSGVLAVLFLVFNEGYLATGPGTDPVRHDLTTEAIRLTRLI
                     RALLPEDGEVAGLLALMLLTEARRTARISASRELVPLDEQDRGAWDAALIAEGHRLVRE
                     RLAAAATGVAPGRYQILAAINAVHTSARDMCDTDWSQVLALYDQLVRLDPSPIIALNRA
                     IAVAELDGPEVALADVDRLEHGLAGYHAYHATRADLLRRLGRDQESRAAYDKAIDLAGN
                     TAETAHLIRRRDRLR"
     gene            complement(17493..17927)
                     /locus_tag="KOI47_RS17795"
     CDS             complement(17493..17927)
                     /GO_function="GO:0003723 - RNA binding [Evidence IEA]"
                     /GO_function="GO:0008173 - RNA methyltransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020643340.1"
                     /locus_tag="KOI47_RS17795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="TrmH family RNA methyltransferase"
                     /protein_id="WP_216204593.1"
                     /transl_table=11
                     /translation="MAAPLWPLHGANLGTLLRSCDAAGACLAVPRLPWVPQALARGNTL
                     RRRSCVHHTGDPLRWLERQRARGVRLVGVELADEAVRLADLPAAREPTVAVLGHEQSGI
                     PPEALDLLDQAVEIPMVGHGATLNVAVAGSLVLYKLAGLL"
     gene            18221..19003
                     /locus_tag="KOI47_RS17800"
     CDS             18221..19003
                     /GO_function="GO:0008276 - protein methyltransferase
                     activity [Evidence IEA]"
                     /GO_function="GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0018364 - peptidyl-glutamine methylation
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009946822.1"
                     /locus_tag="KOI47_RS17800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="putative protein N(5)-glutamine
                     methyltransferase"
                     /protein_id="WP_216217367.1"
                     /transl_table=11
                     /translation="MTATPCSLPELTSRLRAAGCVFAEEEAQLLATAARSPEHLATLVD
                     QRVTGLPLEQVLGWAWFHGLRIAVEPGVFVPRLRTGLLVRQAAALARPGAVVLDLCCGT
                     GAVGAALAATVDGLEVHAADLEPAAVRCARRNLAAAGGRVYEGDLYEPVPARLRAGVDL
                     LLVNAPYVPTDAVDLMPPEARLHEPRTALDGGADGLTVQRRVIAAAPDWLAPGGHLLIE
                     TSEPQAPRLAAACADAGLRPRIIGCPELDATIVLGAAT"
     gene            19042..20082
                     /locus_tag="KOI47_RS17805"
     CDS             19042..20082
                     /EC_number="3.5.4.4"
                     /GO_function="GO:0000034 - adenine deaminase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006146 - adenine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020665995.1"
                     /locus_tag="KOI47_RS17805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="adenosine deaminase"
                     /protein_id="WP_216204596.1"
                     /transl_table=11
                     /translation="MMGLAEFIAGIPKCELHVHIEGTLEPEMMFELAERNDLVLPYTDA
                     AQLRATYNFHDLPSFLKAYYQGMEVLLTEQDFYDLAWAYLTRAHAQNVRYAEIFFDPQA
                     HTSRGVCFGTVIRGLRRALVDAHRLLGLRAQLIMCFLRDLPAGFAMATLLESLPYKEWI
                     VGVGLDSDERGNPPSAFAAVFERARAEGYFLTMHCDVDQENTTEHIRQCLDVVGVDRID
                     HGVNALDDPALHTEIARRGLGLTVCPISNRHVRGDLGHDSLRRMLDLGLRATVNSDDPA
                     YFGGYVTENLLAVSEAAGLGEREVLRLEHNAFEIAWLPAGVRDTYLAELRAYGKDREVS
                     SRAAHA"
     misc_feature    complement(19073..19085)
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 17.22"
                     /tool="antismash"
     gene            complement(20037..21290)
                     /locus_tag="KOI47_RS17810"
     CDS             complement(20037..21290)
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016336958.1"
                     /locus_tag="KOI47_RS17810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="RNA polymerase sigma factor"
                     /protein_id="WP_216204598.1"
                     /transl_table=11
                     /translation="MSGAELEGLLRTLAPQALGAVVRRYGHFDLAEDAVQEALLAAATQ
                     WPAEGAPANPRGWLIRVAARKLTDLLRGEQARRQREDTVLQWTLPERRQAPAADRAAAD
                     ADDTLILLFLCCHPSLSPASQIALTLRAVGGLTTAEIARGFLVPEATMTRRITRAKRSI
                     TGSGKPFGMPTGAEREERLGVVLHVLYLIFNEGYATTSGPSLHRGDLAAEAIRLTRILH
                     HSLPEDSEVAGLLALMLLTDARRPARTGADGSLIPMAEQDRTRWDTSLISEGTALLSVA
                     LPQGPAGPYQLQAAIAALHDEAPSQERTDWPQILALYELLLRISDNPVTALNHAVAVAM
                     VRGARAGLDLLAELAADERLAGDHRLDAARAHLLEMAGEPARARDAYLEAAGRTTNIPQ
                     QRYLYACAARLDTSRSLP"
     gene            complement(21454..21843)
                     /locus_tag="KOI47_RS17815"
     CDS             complement(21454..21843)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009081425.1"
                     /locus_tag="KOI47_RS17815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="YciI family protein"
                     /protein_id="WP_216204601.1"
                     /transl_table=11
                     /translation="MKYILMIPGTQQDYDAMASGAQPGLTAQDMAGIDEFLRAFNQELE
                     ESGEFVDAQGLAAPVHTRRVELREGVPVVTDGPYAETQEVLAGYWIVDCASFDRATEIA
                     AKLGSGPGPQRPIDVRPVAGSEPEL"
     misc_feature    22313..22331
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 19.98"
                     /tool="antismash"
     misc_feature    complement(22314..22332)
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 19.85"
                     /tool="antismash"
ORIGIN
        1 gggcctcgac gactacttca cgcgcgactt cacccacaac atcggcgccg agatcatggg
       61 ccgcaacaag ttcggtccgc agcgcgggcc atggcaggac cacgactggc tcggctggtg
      121 gggcgacgag cctccgttcc gcaccccggt gttcgtcctg acccaccacg agcgcccgtc
      181 gttcaccctc tccgacacca tcttccactt cgtcggtggc gatccggcca cggtgctgga
      241 gcgggcgcgg gaggctgcgc agggcaagga cgtccggctc ggtggcgggc cgaccacggt
      301 ccggcagttt ctcgacgccg atctcgtcga caccatgcat gtggcggtct cgcaggtgga
      361 actcggatcc ggagtgcggc tgtgggagtc ccccgatgag ctgctcgacc ggttccacct
      421 ggagacggtg cccagcccga gcggcgtgac ccaccatctt ttctggcggc gatgactccg
      481 gcggtaagga atacgccacc gggtaccggc cgttgcgagt gcgcgacacg ctcttctgat
      541 gccagctcct tcgctggcat cacccgcgta aaccgaggat ttgctccgaa tccgaagcca
      601 ggttagattc atggtgtcgc gaaaaacgat gtcctgcggc gttgttcgcc ggacatcgcg
      661 cacacatcga tgcaggacgg ttccgatcgg tgagcgtctc cgtgccgaga tcgggcgtcc
      721 cgcccgctcc cggtgtcgac cgcaaccgag gagcgcacca tgcagaagac cgtcaccatc
      781 gtcggagcgg gactgggcgg gctgacgctc gcccgggtgc tccaagccca cggcgtcgcc
      841 gccacgatct acgagggtga ggcgtcggcg acggcgcgcg cccagggcgg cctgctcgac
      901 atccatgaag aaaccgggca ggtcgcgctc cgcgcggcgg gcttgtacga cgagttccgc
      961 gccctggtcc ggccaggcga ggacgccaag cgcgtcgtcg accgccacgg cacgatcctg
     1021 ctcgaccggc ccacggaccc ccgttcggcc cgccccgagg tagatcgcgg cgaactccgg
     1081 cgcctgctca tcgactcgct cgccccggga ccatccggtg gggccacaag ctcaccgcgc
     1141 tccggcacca cccgacgggc ggcttcgacc tcaccttcac ggcgggttcc accgtccgcg
     1201 ccgacgtcgt cgtcggcgcg gacggcgcct ggtcgaaggt ccggccgctg ctcacccagg
     1261 ccgagccgcg ctacagcggt acctgcttcc tcgggatcgc cctcgcctcg ggcggccggg
     1321 accaccgcgc gagcgtggcc acgatcggca gcggcacact gatggcggtc gcgccgggcc
     1381 agggcatcat cgtccaccgc gacgcggacg gcggtgtacg cggttacgtg gcgctgaaca
     1441 agcccgacga gtggatgcgg tcgatcgact tcggtgaccc gaccgccggt ctccaccgcc
     1501 tcgcccacga gttcgatggc tggtcgccgc tgctcaccgc gctcgtgaca ggcagcgacg
     1561 tggagccgtg gctccggccg atccacgcgc tccctgtcgg gctcagctgg aaccgggtgc
     1621 cgggcgtgac gctcgtcggc gacgccgcgc atctgatgtc gcccttcgcg ggcgaaggcg
     1681 ccaacctcgc catgtacgac ggcgccgacc tggcgcgcga gctggccggg caccccgacg
     1741 tcgagactgc gctcgccgcc tacgagaagc ggcttttccc ccgcagccgc gaggtcgccg
     1801 cccactcggc gcacaatctt gagactttct tcggccagga ggcgccgcac agcgtggtca
     1861 cgctgtgcgg aggctcggcc caggctgtca agtcagcggt caggcagccg tggtcttccg
     1921 ggggtgcctc ggggcgcagt cgttcgacgg ccacgtccga cagcagctcc tgcagatcgc
     1981 cccaccgccg gtagatcgtc gacggtgtga ctccggctcg ggccgcgacc aggggcacgg
     2041 tcaatgcctc ccggcccgat tccgctatca gggcgcgtac ggcttcgtgc accgattctt
     2101 ggacccgggc gctgcgcccg cccgggcgca ccatcggttt gcgactcacc gcaccacctt
     2161 aaagcgaagc gattgcctta tcgcggagga gctggtcggc ccgctcaggc catgggtgcg
     2221 agcgggcggg ccggttgtgt ctgcgcgtgg gcgtgtccga cgcgcaggag tacggcctcg
     2281 gagcgggggc gtccgagcag ctgcatgccg atcggcatgc ccgccgggtc gtggcccacc
     2341 ggtagggaaa gcgaggggat gccggtgagg ttggcgggag cgcacagccg cacgtaggca
     2401 tcggagacgc tctcgaccgt accgtcggac caggtgatcg tctccaggtt ggccggtacc
     2461 gcggtcatcg ggaccgtcgg ggcggcgatc acgtcgacct cgtcgagcag gcgtgcccag
     2521 gcctgccgca tcagggtccg ggcgcgctga gcgcgcaggt agtccccggc ggtgatcagc
     2581 tcgccggctt cgagcagggc gcggacgtcc gccgcgtaga ggtctggcac ggcccgcagg
     2641 ctccgttcgt ggtaggcggt ggcctcgggg accatcaggc cccattgagt ggcctggatg
     2701 tagcgggtca tcgggatctc gacctcgacg aggtgggcgc cgaggtcggc gagccggtcg
     2761 atggcggtcc ggaccacggc gtctacgtgc ggatcgacgt ggtcgaagta gtagttgcgt
     2821 ggcaccccga cgcgcagccc ggtcaggtcg gccactgggc ccggccggta gtcgccgtcg
     2881 gtgcagggca gggaggccgg atcccgcggg tcgtgtccgg ccaggacgga caggacgagg
     2941 gaggcgtcct cgacggtgcg ggtgatctgg ccgacgtggt ccagtgacca ggacagcgac
     3001 gtcacgccgt ggcgggagac gaggccgtag gtgggcttga ggccgacgac tccgttgagc
     3061 gaggcgggta cgcggatcga gccgccggtg tcggtgccga gagcgaatgt ggcgatgcgc
     3121 gccgcgacgg cgatggcgga gccgccgctg gatccgcctg cgacgcgcgt ctggtcccag
     3181 gcgttgtgcg tctgcggtgt cgtcaggccg taggcgaact cgtgtgtgtg ggtcttgccg
     3241 agcagaatcg cgccggccgt cctgagccgt gcgaacaccg tgctgtcgga gtcggcgcgg
     3301 tgctcggcgc ggaccctgga gctggcggtg gtggctgtgc cggcaacgtc gatgaggtcc
     3361 ttcaggccca tggggacacc gtgcagggcg ccgcggatcc ggcctgccac gatctcgcgt
     3421 tctgcgtcgc gggccgcgct gcgcgcctgg tccgcctgca ccgccacgta ggcctgcagg
     3481 cggggttcca cctgatcgat gtgatcaagg atcgagtcga ccagttctac gggggatacg
     3541 cggcgttccc gaatcgcgtc cgaggcttcg gcgagggtca gatcaggcag ctgcatcggc
     3601 agtcaccttt cgcgtgttct cctcttccgc gcggtaggcg gaggcgggtg gggtgtcgcc
     3661 gaagtccagt tcccgcagga tggacacgac ggagtggatg tggttggcgg tgaccgctac
     3721 gccggtgtgg cggacgtcgt tgagcggtag accggcacgg gcggccaggc gggctgcctc
     3781 cgagggggtg agttcgacag cggacatgag gcccctccag catctaaagg ctaactgttt
     3841 gctttagtgg acactaggcg ctacggtacc ttaaagcaaa tgaattgctt tagcgaggag
     3901 ttccatgtct aagccgtccc cgaacactgc tgccggcgtc ccctccgcca ccccgccctg
     3961 ctggacggtc ggcgacgtga ccgtccatcg catcgacgag gtgctcctgc ctcctgcgac
     4021 cggtccctgg ctgctgcccg gcgccaccac ggacctggtg ggccgggagg agtggctgcg
     4081 acccgacttc gcggactcgg acggcattct ccagctccac agccacagtt tcgcgttcga
     4141 gaaggacggg atgcgggtgc tggtcgacac cgccatcggc aacggcaaga cgcgggcaaa
     4201 cccggcctgg cacaagctca gcacgggcta cctggacaac ctgcgcgcgg cgggattctc
     4261 cccggactcc atcgacctgg tcctgctcac ccacctgcac accgaccacg tcgggtggaa
     4321 cacgcacgag gtggacggaa catgggtgcc caccttcggc aacgcccgct acgtgacctc
     4381 ccgcaccgag cgggacttct gggccggcta cgacatggac gagccgcgtc ggcacatgtt
     4441 cgaagactct gtggttccgg tggaggaggc agctctgctc gaccttgtcg acgtccccgc
     4501 agacggcgtc gagatcgcct cgggactgcg gctgctgccc acgcctgggc acacgcccgg
     4561 ccacctcgcc atccagctga ccagtcaggg taagacagcg ctgatcaccg gcgactgcat
     4621 ccaccacccc gtccagttcg cccaccccgc catcggctcc tgcgtcgaca ttcatcctga
     4681 gcattccgag gccacccgac gccggatgct ggccgcgctc gccgacaccg acgccctcgt
     4741 cctgggcacg cacttcccgc cgcccaccgc tggccgtgtg gtctcgcacg ggaacagcta
     4801 ccggatgact tccgttcccg cagcctgacc cagatcagaa ggcctggcat tgaaaacaag
     4861 acgggcgccg ctactgggga ctgggtcatc cgtcgtactt ttcgttccaa tgtccctcgc
     4921 gagccgatca ttagcgggcg gacggggacg gtccagagcg gctagcagac cgcggaacta
     4981 ctactcgaac tcggcgcgac gcagacggac gaaggtgcca ttgccgttgc cgcaccgcac
     5041 gatcagctcc gaatccgcga gccaacttcc tgatcccgct gccgaatgcg atacttcggt
     5101 tcagtacgaa cccgagcact gagtcctggt tctggtgact gcgggccctc gggttcagga
     5161 tgaggaaccc caagtttggg ggaacccact tacttcccag tactcctgct cagcctccag
     5221 acgcgagaac atcaactttt tcggcgcgat cgaggtcgat atcgagggcg agctggcgca
     5281 gctcgggccg accggatacc ggccgctccg tgtccgcgac accctgttct gacgacgtgg
     5341 gtccttcccg atcaacggtg gcgtccgcca cgccgccacg aggtcatcgc ggtgcaggcg
     5401 ctggtcgatc accggcaggt acgccacggc gtcgcggccc gtccctcatc cagtgcttgg
     5461 aaggcgtcgg cgagtacgtc catctcgacg tcgattcgct tctgctcggc gagggtgcgc
     5521 tgctggctca ggggctccca gtagcgttaa cgaattttcg gtcgcatata gccgtgacct
     5581 gcggtgatgt tgtcgaggtt tgtcgcggat cgcggccgtg gtaagggccg cggtgaggac
     5641 gttggcggaa gcgctggaca gccactcctg ggtgagcgcc tccagcgccg gcgttgacga
     5701 acacgggctc aactttccgc cggcgtcccg gaatccttgg caggctgggc ggacggcgcc
     5761 gggtcggcgg gctcggccgt ggtggtcggg cggaagagcg cccagcgcca gacccacctg
     5821 ctcgacgagg ccggcctccc cggcccggcg accggttcac cgtcgcggag cagtaccggc
     5881 tctgccgcga cgtcgcggac atcctcgcgg tccgggaatg gtgccgcgcc cacagcatga
     5941 aactgcgcgt gctgtccggc atcgtcaact tggccgcccc cgacgcgacc accaccatgc
     6001 tggtcaacgt cctggtctcg gtcggccagt tccagcacga cctgcaatac gaactcgccc
     6061 gcgacggcct ggccgccgcc tgggcacaag gagcccgctc cggacgtcac cagccacctc
     6121 gacgttcggc gcgcatgacc agaccctccg gcaccagggt cgtggcggtc acggggcgca
     6181 ccgggtggtc gggcagcgga cgcagccgcc acctgccggc cagcgtggca agggtcaggg
     6241 tggtctcgat gaccgcgaag tggtcggcga tgcacttacg cacgccggcg ccgaacggga
     6301 tgaccgcatc gtgcgggatc cgggtgggcc ggtccggcag ccagcggtcg gggtcgaacc
     6361 gatgcgggtc cgggaacacc gccgggtcgc ggtgcacgat atacgggatc accagcaccg
     6421 ggctgcccgc ggggacgtgg tagccgccga gatcgacatc ggcgagcgcg cggcggctga
     6481 tcatccacgc gggtgggtag caccggagta cctcggagat gatccggccg gtgagctcca
     6541 ggcggggcag gtcctcgtag cgggccgcgc ggccgccgag tacctggtcg acctccgtgt
     6601 gcagccgttc ttcgaggtcc gggtggcggc cgagttcgtg gaacgcccag gacagcgcgc
     6661 tggtggacgt ctcccctccg gtggcgagca tggtcatgac ctggtcgcgg atctcggtgt
     6721 cggacagggg ctcgccggtg tccgggtcgc gggccccggt gagcgtggtc agtaggtcgg
     6781 tgtccttggc ctccgccttg tggtgggtcg cgatggcatg cgccgcggcc tggtgcagcc
     6841 cggccagcag ccgggcgtgg cgctggttgc gcggggtcgg cagcctgctg gtcagggccc
     6901 gtaccgggtt gaacatccgg cgctgcacct cgcgcagtgc cagcgggaag tcgcggcgga
     6961 agtcgccgtg cagcgtgccg atggaggagg gcagcagcgc ccggatggtg atgccgagca
     7021 acagaccgtg catctcggtg cggacatcga gacgctgacc gtcgcgccag gtggtcgaca
     7081 gctgctcgat ctcctgccgc atggcctcgg cgtagcccgc catccggttg cgatggaagt
     7141 gcggctgcaa cagccggcgt tgcctgcggt gggtctcccg ctccgaggtg agcacgccgt
     7201 tgccgaccag cacccgcagc tgggctccgc cctcgccctt gtcgaagctg ccggcctgca
     7261 cgaccagcac ctcgcgtgcc atctcggcct cggtcaccag gtagatggtg cgcgggccga
     7321 gtttgatccg cacgacgctg ccatgccgcc gcaacgagtc caggaacgcc agccgacgct
     7381 cacggcgcag gggcagcaga tgaccgacta gcggcagtcc acccgtggcc agcgccggaa
     7441 ccgccatgcc gcccccttcc cggaatcccg tcacggacca cgagggtagg gcagcatccc
     7501 ctggccaggg tgggaaacgg ccagatcggc agtacggatc accgctccgg ccccgctacg
     7561 ccggccgggc accggctggg gcgccgagtc cggccagggc ccgcggcagc cggccctggt
     7621 gcaggacgcc gaggcgctgg gtggcgcggg tgagggcgac gtagagctcg gccgcgccgc
     7681 gtgggccgtc ggccaggatc cgcatcggtt ccaccaccag aacggcgtcg aactccagcc
     7741 ccttcgtctc cgcgggccgg accgcgcccg gcacacccgg cggcccgatc accacgctgg
     7801 tgccctcgcg gccagcctcc tcttgcacga actcctcgat ggcggggcgc agctcctcct
     7861 cggtgacccg cctggaccag ggctccaccc cgcacgaacg gaccgactcc ggtggctgga
     7921 gccccggcgc gaactccgcg agcagggccg cggcgacggc catgatctcc gccggggtgc
     7981 ggtagttcac cgacagcgac cggtagaccc agcgtcccgg cacatacggc tccagcatcg
     8041 cgtcccagga cgtcgcaccg gccgccgacc ggcgctgggc cagatccccg accaccgtga
     8101 aggaccggcc ggggcagcgc cgcatcagca cccgccagtc catctcggac agttcctggg
     8161 cctcgtccac cacgatgtgg cggtaggtcc agtcccggtc cgcggcggcc cgttcggcga
     8221 ggtcccgggt gtcccgctcg acgaagcggt ccgcaaggtc ctcggcgtag agcaggttct
     8281 cggccgccag catgacgtcc tcgtccatct cctcgcggtc cagcttcatg gcgtccatga
     8341 cgtcggccgc gtactcggcc tcggctctcc gctgccgctc ggccacccgc tcggcggcct
     8401 tgtccaccgc cttgtcacga cccagcaggt cgaccagctc gtccagcaac ggcacgtccg
     8461 gcaccgtcca ggcatcgccc tgggcgcgcc acagcgcctg gtcggcgcca gccgcccgca
     8521 ggcgttcggg ggaggagtac agctcggcca gcagggtttc cggggtcagc accggccaca
     8581 gctcgtcgac agcggcggtg aaccgctcgt cctccgcgag ctgcttgagc aggtccgtgc
     8641 gcagctcctc ccatgccttg cggtcctccc gcgtcagcca gccgcggccg atccgggcta
     8701 tcgcccgctc ggtgagcacg tacgtgacga tctcggtgaa gaccgcgcgg gcctcgttgt
     8761 gcggccgccc gctcgccctg gcctcctcga tggcccactc cgcggtctcg gcgtcgatcc
     8821 gcaccgtgac gtcgcccagc gtgatcggta ccggttgctc cggcagccgc tgccgatcgg
     8881 cgaccgccgc cgcgagcacg tccaggatcc gcagcgaacc cttgagccgg gcggcctccg
     8941 gggtgtcctc ggcggtgacc cgcataccgg gcagcaggtc gccgggggtc atgaagacca
     9001 catcggactc acccaacgac ggcagaacgc ggccgatgtg gtccaggaac gccgggttgg
     9061 gcccgaccac gagcacaccg tgccgttcca tccgctcccg ctgggtgtag agcaggtacg
     9121 ccaccctgtg cagcgccacc acggtcttcc cggtgcccgg accgccctcg atcaccagca
     9181 cgccagggtg gtcgagccgg atgatctcgt cctgctcggc ctggatcgtc gccacgatat
     9241 cgcgcatgcc cgcaccgcgc ggcgcgttga ccgccgcgag cagcgccgtg tctccgcgct
     9301 catcctcgcc gggacggccg aacacctcgt cggtgaaatc gagcacctga cgcccccggg
     9361 tgtggaactg gcggcgcctg cgcatgttct ccgggttcgc gccggtggcg acatagaacg
     9421 cgcgcgccgc aggcgcccgc caatcgagca gtaccggatc gtacgcgttc tcctcgtcga
     9481 aaaggccgat ccggccgatg tacagctgtc cgcccgactc ggtgtccaac cggccgaaac
     9541 acagcccggc gtccgccacg tccagccgtt tcgcctcgct ggacagcgcg cgcacctcga
     9601 catcccgttc catgggtgtc tcgccgtttc cccgcaacgc cgcctcgtac gcgccccgca
     9661 ctcgcgtgcg ctcggcgtcg agccgcgcgt acagcccggc gacatgactc cgctccgacc
     9721 gcagctcctc ttcgtacccc tgagccgaca cgttccccct cacagtgaca agaaatgatg
     9781 tttgatccga cggcttcttc ctcgttcatg ggcagcacgt cgcggccccg ctggcgtgcg
     9841 gggtgcctac gcgcgagtcc atttccgcag gttgtggcct tgcccggcaa tcttgcggta
     9901 cgacccgggc cttgccgcaa gcccccggtg cgctatatgt tgagagtggc gggggagtgc
     9961 cgctccttgg gaagtcagaa accgcatcgt gagttcgaag tcattgcggg tggcgctgtc
    10021 tgctttccgg acggtgagat ccgttgcccg tgatgaccag gtcttccacg tagttgggcc
    10081 ggtctgctgg gatggtgccc tcgggcgtgt agcggtcggt ctcgatctcc cactggtggt
    10141 aaccggcgat ccacattttg atggcggcta cggacttgtc gaccgcggtg cattgctcgt
    10201 cgtcgagtcg cagtgtggcg cagattcgcg gcagttcctg ctccaggcgt tggaagcggg
    10261 ggatgtggtc gtggatgacc atgtcgcgca ccgctcgcag ggcttcatcg cgggtgcagc
    10321 cgtgttcacg ttcgacgacc agcacggcgt tgtcgacatc gccgcggggg gcctctttgt
    10381 agacggagtg cacgtcgttg cacaggaggg gcacgtcgat gccgacttgg cgcatcatgc
    10441 ggtactgggg ggtgtggaag agagcgagtg ggacggtgaa gtggccgaat cgctcgccgt
    10501 agtcgaccat caatctggta gcgcctgcgc cgcgccgcac gtggaggaag tgctcccacg
    10561 acgggacatg ggcgttgacg cggtccatgg cctcggcggc gtgggcggcc aggtagtact
    10621 cgaagttgtg ggcggcgcgc gtgatccatg cggcgggcat accttgctgg ctgcgttccc
    10681 acatgtcagc gaagaaggtc acgagcggag aggaaccgcg cggcgacggc cgtccggccg
    10741 ggcggtacag caccgcgatc aggtcgtcga cgaacgtggc cacgcgcgcc ggatcgcgtc
    10801 ccagcgggcc gtcgaactgg tcatcgaaga caaagaagaa cgcaaactgg tccaccgcca
    10861 ggtccaggtc ttcgcctacc gccatcgggt acgcgtatcc ggcgccctgg cccaggtccc
    10921 aggacaggta ccagtgctcg gcctcggggg tgccgagcat gccatgggac ttcatccggg
    10981 cgacgttggc ggtccgcgct cgcgctacct cggggctgga ccgcgcggga aacgggatat
    11041 cgaacacggg caggtccacg acgggcatgt cattctcctt ggacgagtgg gcggtgatct
    11101 ttccgcaggg atcagtggtc atggcagccc tcgattcccg gtgttgaggt ttgtcgtggt
    11161 gtgggtgttg tgcacgatct ggtgacgcac atagacgggc gctccgtgca gttccagagc
    11221 gcgtccgacg atcgcgacag cccgttccac gccggcgcag tagccgcgcg gcgcggcgag
    11281 cagtactcgt ttgtccatca ggctcggccg ttctaggtgg cgcgggtgat gaggaaactg
    11341 atcaggtggt cccactcccg ccgtacgtcg gacgggatgg tgagcgccgc gatggcatcg
    11401 cgggcgcggt cggtgtgctg gcgggcgtgg cggctggtgg tctggccggc gttggtccgt
    11461 tccagcgccg tggtggccgc cgcgaggtcg tcggtggtga gctcgccgtc ggtggcgagg
    11521 atcgcagcga gccgttgcgc ggccgggtcg gcatcggtga gtgtgacgac gatcggcagg
    11581 gagcgtttgc gggcggcgac atcggcaccg gcgggtttcc cggtgacctt cgggtcgccc
    11641 cagatcccca gccagtcgtc catggcttgg aacgccagac caagctgagt gccggctgtg
    11701 cccagcacgg cgatggctcg ggaatccgct tcggtgagca gcgcgccgag ctgacaggcc
    11761 gcgcagatca ggccgccagt cttgccgatc gccatgcgct cccagtcggc gaccgtcacc
    11821 gtcgtgcggg tttcgaacgc caggtcgtcg gcctgtcccg cgcacaaccc caccaccgcc
    11881 tcggccagga ccgcctcggc ctgggggtgc tcggcgagtg tggagaccgc cagggcgagt
    11941 agcgcgtccc cggccagcag cgcggtgtcg acgccgtgga cggcccaggc cgtggggcgc
    12001 ccccgtcgtg tccggtcgcg gtccatgatg tcgtcgtgca gcagggagaa ctcgtgtacc
    12061 agctgcaccg ccaccgcccc tgcgacaaca ccctccgagg ccaggcgctc cgcaggcacg
    12121 cccgtactgc gggcggacag gaacaccagg gcggggcgga gcatcttccc gaccctggca
    12181 ggggccggcc ggccgtgctg gtcggtgagg ccgcagtggt agccggctac ctgcgcgagc
    12241 ctggggtgca gggtggcgat cgcctgccgc aaggcgggca ccgtcaggct gcgtgcctgc
    12301 tgcagaactg cgggagcggc cgttgtgtcg gtaagggacg ggctagccat gacaatcgct
    12361 cccgctgccg tcggggatgt cggagaatcg gcggagagcg gacagcaccg atccgtccag
    12421 cacgggccgg acagctccgt gatcgacgct cgtcaccgga ggggtcatcg gtgatcgctt
    12481 tcggcgagcc gtaccgcgtg cgcgatcagc gtttcgggga tctcgtgctc gggcacggtg
    12541 tccaccacct ggccgcgtac gaagatctgg cccttgccgt tgcccgaggc cacccccaga
    12601 tccgcgtccc gggcctcgcc cgggccgttg accacgcacc ccatcaccgc cacccggatc
    12661 ggcacctcca aaccgtccag cgcggcctgg acctcggcgg tcatcttgta cacatccacc
    12721 tgcgcccgcc cacacgacgg acacgagaca atgtccaacg tgcggggccg cagtcccagt
    12781 gcctgcaaga tcgcctcccc ggcccggacc tcctcaatcg ggtccgcggt caacgacacc
    12841 cggatcgtgt ccccgatccc ctccgacaac agcgcgccga aagcggtcgc tgtcttgatc
    12901 accccttgcg ggggtggccc ggcttcggtc acacccaaat gcaacggata atcgcattgc
    12961 tgcgcgagtt gccggtaggc gtcgatcatc actaccgggt catgatgctt cacgctgatc
    13021 tttagatcgt ggaaaccgtg atcggcgaac aacgacgtct cccacaacgc cgattccacc
    13081 aaagcctccg cacctgcccg cccgccatgt ttgtcgagga ttttcgggtc caggctgccc
    13141 gcgttcacac caatccggat cggcaccccc gcatcccgcg cggcgtgggc gatctcgccg
    13201 acccgatcgt cgaaacgctt gatattcccc ggattcaccc gtaccccagc acatccggcc
    13261 ttgatcgccg cgaacacata cctcggctgg aaatgaatat ccgcgacaac cggaatcgtc
    13321 gacttcgacg cgatcgctgg caacgcatcc gcatcatcct gggagggcac cgccacccgc
    13381 acaatgtcac atccagccgc agtgagctcg gcgatctgct gcaatgtggc atccacatcc
    13441 gcggtcaagg ttgtggtcat cgactgcacc gaaaccggtg caccaccccc caccagcacc
    13501 gtgccgacac ccacctgacg gcagacccga cgaaccgccg gtagcggcaa tcccgtgact
    13561 gggaccatgc acggtcacct ccaccgcatg acggtgacag agacaattgt cgcaggtcaa
    13621 cgcccccttc cggcaacacc cacacgagaa tgtgaacacg agtagtggtc gactattcac
    13681 gacaggagtg gagtgtcacc gccagaaacg cactttcacc ttctcgtgtc cacttcctga
    13741 cacggtgggc tcaccgccac cgcagacagc tcacaacact atggtcgtga ctgaggggag
    13801 gccaccttcg attcgcgggt cggtcacgcc tgcgacagcc atccgaccgg caggcactga
    13861 ctccagacgg cccccagcgc cgaaccccgt cgcgcggcgg tgacactgtc aggcgcagca
    13921 cgaggaaggg gttgtcgtga cactggccgt agccgcgcag ggcgatgggg cggacaagac
    13981 ggggcaggaa cgcttcgcgg agttcctgcg catctacacc tcgctcaaca cccggctggc
    14041 ctacgcgacc gacctcggca tccccctgga ctgggtgccg ggctacaccc cgcccgaccc
    14101 cgcccgccgc cgggggcgga gccgccgcgc ggcacccacc ggactggaat ggctgccctg
    14161 gtgcctgcgc aatgggttcg gctccttcgc cgaggtcagg gtggagcacg tcgagcggtg
    14221 gctggacgaa ctggcccacg cggggtacag cgacgccacc cggggcagga tgctgtccgc
    14281 ggtgtccgcc ttctaccgca agtacctgct ccgggaaggg ctggccgaac agaacccggc
    14341 cgcgctggtc gaccggaaga cccagcacct caaccgctcc ggcggcaccc cttcggtcac
    14401 cgcacgctgg tccttcgagg cgtgccgcgc cctgctgctg gccgcgtacc tcctggccga
    14461 ccgccgccgg gacggccgcc gcgaccgcgc gatggtcgag gtgctgatcg gcaccggcgt
    14521 gcgagcggaa gaactcgtcg gcaccaacct caccgactac cgcaggccca ctggcgggga
    14581 catcggcatc ctgcgcatcc acggcaaggg cgccaaggac cgcgaggtcg ccctcgcgcc
    14641 gccggtggcc gacgcggtgg acacctatct cgccgaacgc aggcccccgg ccgccccggc
    14701 ggtccgcggc caggtcgggc ccacacccgc ggaaccactg ttcatcacca gcaccggccg
    14761 acgcgtgcac gtctcccatg tccaggccct gctgcgcagg ctgtgcgcca ccttcgcccc
    14821 cgcgccggac gcgccgcccc cgcgcgcacg ctggctgcgg gacctgctcg gcaccgaaca
    14881 ggccgcgctg atcgccagcc acctcggccc gctccgggac accatccacc cacactcggc
    14941 ccggcactcc tacgccacgc acgccgtcga acgcggcgtg ccgccccgcc aggtgcagca
    15001 ggacctcggc cattccgccc tgtccaccac cgaggggtac ctgcacgacg aggacaacat
    15061 ccgcaactcc ggcgcgcacg agctggcgcc ggcgctgcac cgtggctggc tggccgcccc
    15121 ctagtgcggt acggatctcc cttcaagaaa cccgggaagc ggtgtcggat cggggcggtg
    15181 gtgttcgtag caggggtgag gctacccacc aggggcggcg ccaaggcaaa ggaaccgtga
    15241 tcgtgaagct gacaatcatg actcaggtca ctgtcgatgg agtgatgcag ggaaacggcg
    15301 ccacgtcgga tgaccggagg aacggattcg aacgcggcgg atgggcccgg gggaagggcg
    15361 acgacgagac caggacgttc atcacgcaga cctaccagcg cgcagcggcg ttcctgttcg
    15421 gccggcgcac ctacgagctg ttcgccggtt cctggggatc aatcgaccag atgcgtgcac
    15481 atcccatcgg tgcggccttg aacgagaccc ccaagtacct tgcctcgacc acgctcaccg
    15541 cgccgcgttg ggaggacacg accgttctcc gtggtgacct cgcggcggcc atcggtgagc
    15601 tgaaggccaa gcccgggggt gagctgcagg tgcacggcag cggcgtgctg acccggtggc
    15661 tgctggagaa cggtctggtc gacgagatga ctctgctcgt gatcccggtg atcctcggcc
    15721 agggcgcgag actgttcccc gaggccggtc cggatcttgc gctcgacctg gtggagtcgc
    15781 gggtcgactc gaagggcgtg atgatccagg tataccggcc ggacgggcgc ccgcagtatg
    15841 caacggcctg aagtcgctga ccaccgaacc acgccgtctt ggcaccacag gagatgatct
    15901 tcagatgcag tacctggttt ccgtgatcga tgacaagagc aatcccggca gcacggacag
    15961 gcggcctgcc atcagcgcgt tcaacgaacg actgatcgcc gagggctact gggttttcgc
    16021 gggcgggctc gcggacaccg atacggccac ggtcatcgac aaccggggcg agcaggcggt
    16081 gttcagcgac gggccgttcg tggagtcgaa ggagtacctc gccggcatct gggtgtggga
    16141 ggcgcccgat ctggatgtgg cgctcaagct cgccgccgag gcgtcgaagg tctgcgatcg
    16201 gaaggtcgag gtgcggccgt tccggtgagc gacgtcgagg aggcgatcac ccgggcccac
    16261 cgcgcggagt gggcgcgggt ggtggccgcc ctgaccaggc gcttcggtga cctcgacacc
    16321 gccgaggagg cggcggccga ggcgttcgcg accgccgtcg agcgatggcc ggccgacggc
    16381 gtgcccccca atcccggcgc ctggctgacc accaccgcca accacaaggc catcgaccgg
    16441 atccggcgcg agaacaagcg cgatgacaag cacaaggagg cgcagatggt gtacgacgac
    16501 tcgcgcgagc cgctcggcgc catcgacggt gcgatcgagg acgagcggct tcggctgatc
    16561 ttcacctgct gtcacccggc actcgcgatg cagacccgcg tggcgctgac gctgcgcatg
    16621 gtcggcggtc tcactgtacc cgagatcgcc agggccttcc tggtggccga gaccgccatg
    16681 gggcaacgga tcacccgcgc gaaggccaag atcaaggcgg cgcgcatccc ttaccgggtg
    16741 ccgtccgcgg aggatctccc ggcacgcgtc tccggcgtac tcgccgtcct tttcctcgtc
    16801 ttcaacgagg gctacctggc caccggcccc ggcaccgatc ccgtacgtca cgacctgacc
    16861 accgaggcga tccggctcac ccgcctgatc cgtgccctcc tgcccgagga cggtgaggtg
    16921 gccgggctgc tggcgctgat gctcctcacc gaggcccgcc gcaccgcccg gatctcggcc
    16981 agccgcgaac tggtcccgct cgacgagcag gaccgtgggg cctgggacgc ggcgctgatc
    17041 gccgagggcc atcggctggt gcgcgagcgc ctggccgctg ccgccaccgg ggtggctccc
    17101 gggcgctacc agatcctcgc cgcgatcaac gcggtgcaca cctccgcccg cgacatgtgc
    17161 gacaccgact ggtcacaggt cctcgccctc tacgaccaac tcgtccgcct cgacccctca
    17221 ccgatcatcg ccctcaaccg ggccatcgcg gtcgccgagc tcgacggccc ggaggtggca
    17281 ctcgcggacg tcgaccgcct tgagcacggg ttggcgggct atcacgccta ccacgccacc
    17341 cgcgccgacc tgctccgccg gctgggccgc gaccaggagt cacgcgcggc ctacgacaaa
    17401 gccatcgacc tggcgggcaa caccgccgag accgcccacc tgatccgtcg ccgcgaccga
    17461 ctgcggtagc gcacacggat ccgggcacgt ggtcagagca atccggcgag cttgtacagc
    17521 acgagggagc ccgccacggc cacattgagc gtggcgccat ggcccaccat cgggatctcc
    17581 accgcctgat cgagcaagtc cagcgcctcc ggcggaatgc cgctctgctc gtgcccgagc
    17641 accgccaccg tgggctcccg cgcggcaggc aggtcggcga gccggaccgc ctcatcggcc
    17701 agctcgaccc cgaccagccg gacgccccgc gcccgttgcc gttccagcca gcgcagcgga
    17761 tcgccggtat ggtgtacgca gctccggcgc cgcagcgtgt taccccgcgc gagcgcctgc
    17821 ggcacccagg gcaaccgggg caccgcgaga caggcacctg ccgcgtcaca actccgcagc
    17881 agggtgccga ggttcgcacc atgcagcggc cacagcggag ccgccaccac atgaccccag
    17941 cacgaatggg aacgacggcg ccggttcgcc cggatctccc cacgggtccg ggcgcggatc
    18001 gcggcgctca ccgggcaggg gagtgatcct ccccgaacac cagaacagta ctcatcggcg
    18061 agggtgcttc gcggcgcacc ccaaaggcca tcgacgacaa cccgaccgta gccagcatac
    18121 cggcccctgc ggcgccatca tgcaccggcg ccgcttcggc accgtgcccc gcatcaggta
    18181 caaccagcac tacctggacg tgccggagca gggggtgttg atgacggcta ctccgtgctc
    18241 gctgcccgaa ctcaccagca ggctccgcgc cgcgggctgc gtgttcgccg aggaggaggc
    18301 gcagctgctc gccacggccg cgcgctcccc agaacacctc gccacgctgg tggaccagcg
    18361 ggtaaccggc ctgccactgg aacaggtcct cggctgggcc tggttccacg gcctgcggat
    18421 cgccgtggaa ccgggtgtct tcgtgccccg cctgcgcacc gggctgctcg tgcgccaggc
    18481 ggccgcactc gcacggcccg gcgcggtggt gctggacctg tgctgcggca ccggcgcggt
    18541 gggtgccgcg ctggccgcca ccgtggacgg gctcgaggtg cacgccgccg acctggaacc
    18601 cgcggcggtg cgctgcgccc gccgcaacct cgcggccgcg ggcggccggg tgtacgaggg
    18661 cgacctgtac gagccggtac cggcccggct ccgcgcgggg gtggacctgc tgctggtgaa
    18721 cgcaccctat gtccccaccg acgcggtcga cctgatgcca ccagaggccc gcctgcacga
    18781 gccgcgcacg gcgctggacg gcggtgcgga cgggctcacc gtgcagcgca gggtgatcgc
    18841 cgcggcaccg gactggctgg cacccggcgg ccacctgctg atcgagacca gcgaaccgca
    18901 ggcaccgcga ctggccgcgg cctgtgccga cgccgggttg cggccccgga tcatcggctg
    18961 ccccgagctg gacgccacca tcgtgctcgg cgcggccacc tagatcaggc cgatgtcggc
    19021 ggctgccact acgatgacgg catgatgggg ctcgccgaat tcatcgccgg tattccgaaa
    19081 tgcgagctgc acgtacatat cgagggaacg ctcgaaccgg agatgatgtt cgagctggcc
    19141 gagcgcaatg atctcgtgct gccgtatacc gacgccgcgc aactgcgcgc cacctacaac
    19201 ttccatgacc tgccgtcgtt cctgaaggcg tactaccagg gcatggaggt cctgctgacc
    19261 gagcaggact tctacgatct cgcctgggcc tacctgacca gggcgcatgc ccagaacgtt
    19321 cgctacgccg agatcttctt cgacccgcag gcgcacacct cgcgcggtgt ctgcttcggc
    19381 accgtcatcc gcggcctgcg gcgggcgctg gtggacgccc accgcctgct cggcctgcgc
    19441 gcgcaactga tcatgtgctt cctgcgcgac ctgccagcgg gatttgccat ggcgaccctg
    19501 ctggaatccc tgccgtacaa ggaatggatc gtcggggtcg ggctcgactc cgacgagcgg
    19561 ggcaacccgc cctcggcctt cgccgccgtc ttcgaacgcg cccgcgccga gggctacttc
    19621 ctcaccatgc actgcgatgt ggaccaggag aacaccaccg agcacatccg gcagtgcctg
    19681 gacgtggtcg gcgtggaccg catcgaccac ggcgtcaacg cgctggacga ccccgcgctg
    19741 cacaccgaga tcgcccgccg cggactcggc ctgaccgtgt gcccgatctc caaccgccat
    19801 gtccggggcg acctcggcca cgactcgctg cggcggatgc tggacctcgg gctgcgggcc
    19861 accgtcaact ccgacgaccc ggcgtatttc ggcggctacg tcaccgagaa cctgctcgcg
    19921 gtgagcgagg ccgccgggct gggggagcgg gaggtgctcc gcctggagca caacgcgttc
    19981 gagatcgcct ggctgcctgc gggtgtgcgg gacacctacc tcgccgagtt gcgggcctac
    20041 ggcaaggacc gggaggtatc cagccgcgcg gcacacgcgt agaggtaacg ctgttgcggg
    20101 atgttcgtgg tgcgcccggc agcctccagg taggcatccc tggcccgcgc cggttcgccg
    20161 gccatttcca gcaggtgcgc ccgggcggcg tccagccggt gatcgcccgc cagccgctcg
    20221 tcggccgcga gttccgccag caggtcgagc cccgcgcggg caccccgcac catggccacc
    20281 gccaccgcgt ggttcagcgc ggtcaccggg ttgtccgaga tacgcagcag cagttcgtac
    20341 agcgccagga tctgcggcca gtcggtccgc tcctggctgg gtgcctcgtc gtgcagcgcg
    20401 gcgatcgcgg cctggagctg gtacggcccg gccgggccct ggggtagcgc gacgctgagc
    20461 agtgccgtgc cctcgctgat gaggctggtg tcccaccggg tgcggtcctg ctcggccatc
    20521 gggatgagcg agccgtcggc gccggtgcgg gccggcctgc gcgcgtcggt gagcagcatc
    20581 aatgccagca gccctgcgac ctcgctgtcc tcgggcagcg agtggtgcag gatgcgggtg
    20641 agccggatcg cctcggccgc gaggtcgccg cggtgcaggc tcggtccgga ggtggtggcg
    20701 tacccctcgt tgaagatcag gtacagcaca tgcagcacga ccccgagccg ttcctcccgt
    20761 tcggcgccgg tgggcatgcc gaacggcttg ccgctgccgg tgatgctccg cttggccctg
    20821 gtgatccgcc gcgtcatcgt cgcctccggc acgaggaagc cacgggcgat ctccgctgtg
    20881 gtcagcccgc ccaccgcacg cagcgtcaac gcgatctgcg aggcagggga gagggagggg
    20941 tggcagcaca ggaacagcag gatcaacgtg tcgtcggcgt ccgctgccgc ccggtcggcc
    21001 gcgggggcct gccggcgctc ggggagggtc cactggagca cggtgtcctc ccgctgcctg
    21061 cgggcctgct cgccgcgcag caggtcggtc agcttgcgag cggccacccg gatcagccag
    21121 ccccggggat tggccggagc accctcggca ggccactggg tcgccgccgc cagcagcgcc
    21181 tcctgcacgg cgtcctcggc gaggtcgaag tgaccgtacc gccggacgac cgcgccgagg
    21241 gcctgcggcg ccagggtgcg cagcaggccc tccagctcgg cgccggacat ctgcccgctc
    21301 agcgcctgtt gctgaacttg cggacgcggc cggctcggcc gggctcggac acggtcacga
    21361 tcgtcacctt cgctggtcat gcgcccggcc tcgccgccgc gcgagttctt ccactcatcc
    21421 tgagcaggca aagtccagtt ccggaacagg ctttcagagt tccggctccg atcccgccac
    21481 cggccgcacg tcgatcgggc gctgcggacc gggacccgaa ccgagcttgg cggcgatctc
    21541 ggtcgcccgg tcgaagctgg cgcagtccac gatccagtag cctgccagca cctcctgggt
    21601 ctccgcgtac ggcccgtcgg tcaccaccgg cacgccttcc ctcagctcca cccgcctggt
    21661 gtgcaccggg gcggcgaggc cctgggcgtc cacgaactcg ccggattcct ccagctcctg
    21721 gttgaaggcg cgcaggaact cgtcgatccc ggccatgtcc tgcgcggtca ggccgggctg
    21781 tgcaccgctg gccatggcgt cgtagtcctg ctgggtaccg gggatcatca ggatgtactt
    21841 catggtcggc tccttcgtcg tgttcgtcat gtctttcggg gggcaggcac ctcgcgtgcc
    21901 cgcctgcatt ggatacgtcg gagccgaaca tcgggaccgg acatcctcgc gaagcgaggc
    21961 ccggatacga cttacttaac ataatgtagc ttatcggcgt tcgagatata ccaggagtcg
    22021 acggcgcact ggccgtcggt gttgttccct gcgctgcgga ccgtgccgtc cgcgcgcaga
    22081 ccgagagtgt gggtggaacc cgccgccacc gcgacgacgt cgcgccagtc tgtgacctca
    22141 cattgcccgt ggctgttgtc tccggctgca aggactcgtc cgaatgccgt gaccgcaacg
    22201 gtgtggtagc tgcccgcggc caacgccacc aagtcttccc acccatcgac gtcacacgcc
    22261 ccggtcgtcc ggtctccggt cgccaggaca cgcccgtcac ttcggagacc gacggtgtgt
    22321 agatatccag cccccacggc ggcgaggtcg
//
